task
stringclasses
5 values
input
stringlengths
89
339
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1nc(NC(=O)/C=C/c2cc(Br)ccc2F)sc1C ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. C1(=O)CC[C@@H](C(C)(C)C)C[C@H]1C[NH+](C)C ### Response: C[NH+](C)C[C@@H]1C[C@H](C(C)(C)C)CCC1=O
canonicalization
### Instruction: Canonicalize the following SMILES string. C1CC[C@@H]([NH+]1CC(N1[C@@H](c2ccc(cc2)C(F)(F)F)C[C@@H](O)C1)=O)CO ### Response: O=C(C[NH+]1CCC[C@@H]1CO)N1C[C@H](O)C[C@@H]1c1ccc(C(F)(F)F)cc1
functional_group
### Instruction: Does the molecule contain a halide group? O=C(CCNC(=O)c1nc2ccccn2n1)NCc1cccc(F)c1 ### Response: Yes
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CSC[C@H](C)N(C)S(=O)(=O)N1CCc2ccccc2C1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. C(C([O-])=O)[C@@H](C)NC(=O)CS[C@H]1CCS(=O)(C1)=O ### Response: C[C@H](CC(=O)[O-])NC(=O)CS[C@H]1CCS(=O)(=O)C1
canonicalization
### Instruction: Canonicalize the following SMILES string. CC([S@](=O)CCNC(c1c(Sc2c(cccc2)C#N)cccc1)=O)(C)C ### Response: CC(C)(C)[S@](=O)CCNC(=O)c1ccccc1Sc1ccccc1C#N
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]NCc1cc(CC)no1 Fragment 2: [15*][C@H]1[C@@H](C)[C@H](OC)C1(CC)CC ### Response: CCc1cc(CNC(=O)N[C@H]2[C@@H](C)[C@H](OC)C2(CC)CC)on1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1c(C(=O)NC[C@H](C)C(=O)OC(C)C)oc2c1C(=O)CC(C)(C)C2 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCCS(=O)(=O)CC(=O)N[C@@H](C)Cc1c(Cl)cccc1Cl ### Response: 3
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Cc1nn(C)cc1CN1CCN(C(=O)[C@@H]2C[C@@H]2C)CC1 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[C@@H](NC(=O)N(C)C[C@H](O)CN1CCOCC1)C(C)(C)c1ccccc1 ### Response: 4
functional_group
### Instruction: Does the molecule contain a nitro group? Cc1ccc(N(C)CC(=O)Nc2ccccc2[N+](=O)[O-])c(C)c1 ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]Nc1ccc(N[5*])cc1 Fragment 2: [5*]Nc1ccc([16*])cc1 ### Response: Cc1ccc(/C=C/C(=O)Nc2ccc(NC(=O)OC(C)(C)C)cc2)o1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]CCN1C(=O)[C@H](C)SC1=S Fragment 2: [16*]c1ccc(C)cc1 ### Response: Cc1ccc(-c2nnc(CCN3C(=O)[C@H](C)SC3=S)o2)cc1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC1=C(C(=O)CSc2nnc(-c3c[nH]c4ccccc34)o2)C[C@H](C)N1CC(F)(F)F ### Response: 3
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(=O)c1ccc(N[C@@H]2CCN(c3ccc(Cl)cc3)C2=O)cc1 ### Response: 2
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC[NH+](Cc1cccc(C(=O)NC)c1)C[C@@H]1COc2ccccc2O1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? CS(=O)(=O)N1CCC[C@@H](Cc2cncc(-c3ccc(F)cc3)n2)C1 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[C@@]1(c2ccc(C[NH3+])cc2)NC(=O)NC1=O ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(C([C@@H]2[C@H](n3c(N=C2C(=O)OC)nnn3)c2ccc(Cl)cc2)=O)cc(c(OC)cc1)OC ### Response: COC(=O)C1=Nc2nnnn2[C@H](c2ccc(Cl)cc2)[C@H]1C(=O)c1ccc(OC)c(OC)c1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CCc1ccc([C@@H]2C[C@H](C)CCN2c2ncc([N+](=O)[O-])c(N)n2)o1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a nitro group? Cc1cccc(C)c1C[NH2+][C@@H](C)CN1CC[NH+](C)CC1 ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. C[C@@H]1CCC[C@@H](CCNC(=O)N[C@@H]2C=C[C@H](CO)C2)C1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [12*]S(=O)(=O)c1cc(N)c(C)cc1OC Fragment 2: [5*]N1C[C@@H](C)S[C@H](C)C1 ### Response: COc1cc(C)c(N)cc1S(=O)(=O)N1C[C@@H](C)S[C@H](C)C1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1OC ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCCCCN(C(C)C)S(=O)(=O)c1cnn(C)c1 ### Response: 5
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CCOc1ccccc1NC(=O)COC(=O)c1c2c(nc3ccccc13)CC[C@@H](C)C2 ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [3*]Oc1ccc2c(c1)OCO2 Fragment 2: [3*]OCCN[5*] ### Response: O=C(NCCOc1ccc2c(c1)OCO2)c1cc(C2CC2)on1
canonicalization
### Instruction: Canonicalize the following SMILES string. C(=O)(CCOCC(F)(F)F)N1C[C@H](C(=O)OC)[C@@H](C)C1 ### Response: COC(=O)[C@H]1CN(C(=O)CCOCC(F)(F)F)C[C@@H]1C
canonicalization
### Instruction: Canonicalize the following SMILES string. O=S(=O)(Cc1cc(cc(c1)C)C)CCC[C@H]([NH3+])C ### Response: Cc1cc(C)cc(CS(=O)(=O)CCC[C@@H](C)[NH3+])c1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. COc1ccc(OC)c(NC(=O)Nc2cc(N3CCN(Cc4ccccc4)CC3)ncn2)c1 ### Response: 0
functional_group
### Instruction: Does the molecule contain a ketone group? C[C@@H]1CO[C@@H](C)CN1C[C@H](O)COC(C)(C)C ### Response: No
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)c1ncccc1C Fragment 2: [5*]Nc1c(C#N)cnn1C ### Response: Cc1cccnc1C(=O)Nc1c(C#N)cnn1C
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [8*]C(C)(C)C Fragment 2: [1*]C(=O)CS(=O)(=O)[C@H]([8*])C ### Response: C[C@@H](c1ccccc1)S(=O)(=O)CC(=O)Nc1cc(C(C)(C)C)no1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC[C@H]([NH2+][C@@H](C)C[C@@H]1CCCCC[NH2+]1)C(C)C ### Response: 0
functional_group
### Instruction: Does the molecule contain a amide group? CCC1(CC)[C@@H](OC)C[C@@H]1N(C)C(=O)c1cn2cccnc2n1 ### Response: Yes
functional_group
### Instruction: Does the molecule contain a nitrile group? C[C@@H](OC(=O)C1=NN([C@@H]2CCS(=O)(=O)C2)C(=O)CC1)C(=O)Nc1ccc(N2CCCCC2)cc1 ### Response: No
canonicalization
### Instruction: Canonicalize the following SMILES string. [C@@H]1(CO)CCCCN1c1ncncc1 ### Response: OC[C@@H]1CCCCN1c1ccncn1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Nc1cc(N2CCC[C@@H](c3n[nH]c(=O)n3-c3ccccc3)C2)ncn1 ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]Nc1nnc([14*])o1 Fragment 2: [1*]C(=O)C[8*] ### Response: Cc1ccc(CC(=O)Nc2nnc(-c3ccc(C)cc3)o2)cc1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(ccc(C)c1)-n1c(nnc1N1CCOCC1)SCC(NCC)=O ### Response: CCNC(=O)CSc1nnc(N2CCOCC2)n1-c1ccc(C)cc1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(cc(cc1C)C[S@](CCN=[N+]=[N-])=O)C ### Response: Cc1cc(C)cc(C[S@@](=O)CCN=[N+]=[N-])c1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? O=C(NC1CCCC1)c1ccc(Cn2nc(N3CCN(c4ccccc4)CC3)ccc2=O)o1 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCCC1(CNC(=O)C2C[C@@H](C)O[C@@H](C)C2)CC1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. O=C1NC2=NC(SCc3c(C)cccc3)=NC(=O)[C@H]2[C@@H](C(=O)Nc2ccc(cc2)F)C1 ### Response: Cc1ccccc1CSC1=NC(=O)[C@@H]2C(=N1)NC(=O)C[C@@H]2C(=O)Nc1ccc(F)cc1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC(=O)Nc1c(C)nn(-c2ccc(Cl)cc2)c1N1CCC(C(=O)NCCc2ccccc2)CC1 ### Response: 3
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(/C(N)=N/OC(=O)Cc2ccccc2[N+](=O)[O-])cc1 ### Response: 2
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(NC(=O)C)ccc(cc1)N1C[C@H](CC1=O)C(Nc1nc2ccc(cc2s1)[N+]([O-])=O)=O ### Response: CC(=O)Nc1ccc(N2C[C@@H](C(=O)Nc3nc4ccc([N+](=O)[O-])cc4s3)CC2=O)cc1
functional_group
### Instruction: Does the molecule contain a aldehyde group? COc1ccc(/C=C/C(=O)c2ccc(C)cc2)cc1O ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. C[C@H](Cc1cccs1)N(C)C(=O)N1CC[C@@H](CC(=O)[O-])C1 ### Response: 2
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC[NH+](CC)CCN1C(N)=[NH+]C[C@@]12CCCC(C)(C)C2 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]Nc1ccc(Cl)cc1Cl Fragment 2: [1*]C(=O)[C@@H]1C[C@H]([13*])NS(=O)(=O)N1C ### Response: CCn1cc([C@H]2C[C@@H](C(=O)Nc3ccc(Cl)cc3Cl)N(C)S(=O)(=O)N2)c(C)n1
canonicalization
### Instruction: Canonicalize the following SMILES string. C1[NH+](C[C@@H]2C[C@@H]2c2ccccc2)CCC(C1)C(=O)N1CCC(CC1)C ### Response: CC1CCN(C(=O)C2CC[NH+](C[C@@H]3C[C@@H]3c3ccccc3)CC2)CC1
functional_group
### Instruction: Does the molecule contain a halide group? COc1cccc(/C(C)=C/C(=O)O[C@@H]2CCS(=O)(=O)C2)c1 ### Response: No
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC(=O)Nc1cc(NC(C)=O)cc(C(=O)O[C@H](C)C2CC2)c1 ### Response: 0
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N1CCCCC[C@H]1[13*] Fragment 2: [9*]n1ccccc1=O ### Response: COc1ccc([C@@H]2CCCCCN2C(=O)Cn2ccccc2=O)cc1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1cc(cc(CNC(N2CCC[C@H](C2)CCO)=O)c1F)F ### Response: O=C(NCc1cc(F)ccc1F)N1CCC[C@@H](CCO)C1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*][NH+](C)CC[C@H](C)O Fragment 2: [4*][C@@H](C)C[8*] ### Response: C[C@H](O)CC[NH+](C)[C@@H](C)Cc1nc2ccccc2s1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1cncc([N-]S(=O)(=O)c2c(Cl)cc(Cl)cc2Cl)c1 ### Response: 2
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? Cc1cc(C)c(C(=O)[C@H]2CSCCS2)cc1C ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1([N-]S(=O)(=O)c2sc(C(=O)[O-])c(C)c2)cc(c(cc1)F)F ### Response: Cc1cc(S(=O)(=O)[N-]c2ccc(F)c(F)c2)sc1C(=O)[O-]
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Cc1cccc(C[NH+]2CCC(CNC(=O)[C@@H]3C=C4C(=O)[NH+]=c5ccccc5=C4N3C)CC2)c1 ### Response: 4
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]Nc1ccccc1 Fragment 2: [1*]C(=O)[C@@H]1CCCN([5*])C1 ### Response: COC(=O)c1cc([N+](=O)[O-])ccc1N1CCC[C@@H](C(=O)Nc2ccccc2)C1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)(C)c1cc(NC(=O)c2ccc(F)cc2)n(-c2ccccc2)n1 ### Response: 3
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(-c2oc(nn2)[C@H]([NH+](CCOC)C)C)cc(ccc1)Cl ### Response: COCC[NH+](C)[C@H](C)c1nnc(-c2cccc(Cl)c2)o1
canonicalization
### Instruction: Canonicalize the following SMILES string. c1c(ccc(Cl)c1)CN1CCN(C(CCSCC)=O)CC1 ### Response: CCSCCC(=O)N1CCN(Cc2ccc(Cl)cc2)CC1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC(C)OC(=O)c1cc(-c2ccc(/C=C3/C(=O)N(C)C(=O)N=C3[O-])o2)ccc1Cl ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(=O)Nc1cccnc1-c1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a halide group? O=C(N=C1NCCCCCN1)c1ccc(Br)cc1 ### Response: Yes
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? O=C(NCCc1ccc(Br)s1)c1ccc2ncsc2c1 ### Response: 2
functional_group
### Instruction: Does the molecule contain a ether group? CC[C@@H](CO)[NH2+]C[C@H]1C(=O)O[C@@H]2C[C@@]3(C)CCC[C@H](C)[C@@]34O[C@H]4[C@@H]21 ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [1*]C(=O)[C@H](C)O[3*] Fragment 2: [1*]C(=O)[C@@H]1CCCN([5*])C1 ### Response: C[C@H](OC(=O)[C@@H]1CCCN(S(=O)(=O)c2ccc(F)cc2)C1)C(=O)N1CCCCCC1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. O=C(NC1CCCCC1)c1cn(C2CC2)cc(C(=O)NC2Cc3ccccc3C2)c1=O ### Response: 3
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCc1ccc(NC(=O)CN2C(=O)C(c3ccc(C(C)(C)C)cc3)=NC2(C)C)cc1 ### Response: 3
functional_group
### Instruction: Does the molecule contain a carboxyl group? COc1ccc2sc(N(Cc3ccco3)C(=O)c3ccc4ncsc4c3)nc2c1 ### Response: No
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(F)c(cccc1)S(=O)(=O)/N=C(/c1cn(nc1C(C)(C)C)C)[O-] ### Response: Cn1cc(/C([O-])=N/S(=O)(=O)c2ccccc2F)c(C(C)(C)C)n1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [4*][C@H]([8*])/C([O-])=N/C(=N)N[5*] Fragment 2: [11*]Sc1ccccc1 ### Response: N=C(/N=C(\[O-])[C@H](Sc1ccccc1)c1ccccc1)Nc1nc2ccccc2o1
ring_counting
### Instruction: Count the six-membered rings in the following molecule. Nc1c(-c2ccccn2)nsc1C(=O)NCc1ccc(C(F)(F)F)cc1 ### Response: 2
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [11*]S[C@@H](C)/C([O-])=N/S(=O)(=O)c1cc(C)ccc1C Fragment 2: [4*]Cc1ccccc1 ### Response: Cc1ccc(C)c(S(=O)(=O)/N=C(\[O-])[C@H](C)SCc2ccccc2)c1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [5*]N(C)C Fragment 2: [1*]C(=O)c1cc(N[5*])ccc1F ### Response: CC(C)CC(=O)Nc1ccc(F)c(C(=O)N(C)C)c1
functional_group
### Instruction: Does the molecule contain a aromatic_ring group? C[C@H](CO)[C@H](C)NC(=O)NCCc1c[nH]c2ccc(F)cc12 ### Response: Yes
canonicalization
### Instruction: Canonicalize the following SMILES string. c1(oc(C)cc1C(=O)NCCNC(=O)C(C)C)C ### Response: Cc1cc(C(=O)NCCNC(=O)C(C)C)c(C)o1
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC(C)[S@](=O)c1ccc(C(=O)NCc2cccnc2-n2cccn2)cc1 ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. Cc1oc(cc1C1OC(=O)/C(=C\c2ccc(c(c2)F)N2CCOCC2)N=1)C ### Response: Cc1cc(C2=N/C(=C/c3ccc(N4CCOCC4)c(F)c3)C(=O)O2)c(C)o1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCOC(=O)c1c(NC(=O)c2c([N+](=O)[O-])cnn2CC)sc2c1CCCC2 ### Response: 2
ring_counting
### Instruction: Count the six-membered rings in the following molecule. CC/C=C(/C)C(=O)Nc1ccc(OC)c(OC(F)F)c1 ### Response: 1
canonicalization
### Instruction: Canonicalize the following SMILES string. O(C)c1c(cc(n(CC(Nc2ccc(C)cc2)=O)c1)CSc1ncccn1)=O ### Response: COc1cn(CC(=O)Nc2ccc(C)cc2)c(CSc2ncccn2)cc1=O
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? COc1ccc(C)cc1NC(=O)[C@@H]1COc2ccc(F)cc2C1 ### Response: 1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CCN(C[C@@H](C)C#N)C(=O)Nc1ccc2c(c1)NC(=O)[C@H](C)O2 ### Response: 3
ring_counting
### Instruction: Count the five-membered rings in the following molecule. Cc1cc(C)nc([C@@H](C#N)C(=O)CCC(=O)Nc2nccs2)n1 ### Response: 1
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [16*]c1cccc(Br)c1 Fragment 2: [4*]Cc1ccc(S(N)(=O)=O)cc1 ### Response: NS(=O)(=O)c1ccc(CN[C@@H]2CC(=O)N(c3cccc(Br)c3)C2=O)cc1
functional_group
### Instruction: Does the molecule contain a ester group? C[C@@H](C(=O)N(C)CC(=O)Nc1ccc([S@@](C)=O)cc1)n1cccn1 ### Response: No
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? C[C@@H](c1ccccc1)[C@@H](CC(=O)[O-])C(=O)[O-] ### Response: 5
ring_counting
### Instruction: Count the five-membered rings in the following molecule. CC[C@](C)([NH3+])CN1CC[NH+](CC2CC2)CC1 ### Response: 0
functional_group
### Instruction: Does the molecule contain a ketone group? CCC(=O)c1ccc(F)c(F)c1 ### Response: Yes
fragment_assembly
### Instruction: Assemble these two molecular fragments into a single molecule. Fragment 1: [9*]n1c(C)c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc12 Fragment 2: [16*]c1ccc(C)cc1 ### Response: Cc1ccc(-n2c(C)c(C)n3c4c(=O)n(C)c(=O)n(C)c4nc23)cc1
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? CC(C)[C@@H](CO)NC(=O)[C@@H](C)NC(N)=O ### Response: 4
chain_length
### Instruction: What is the length of the longest acyclic carbon chain in the molecule? [NH3+][C@H]1CCCCC[C@@H]1C(=O)OCC1CCCCC1 ### Response: 1
functional_group
### Instruction: Does the molecule contain a ether group? CCO[C@H]1C[C@@H]([O-])C12CC[NH+](Cc1cc[nH]c1)CC2 ### Response: Yes