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METHODS |
Epithelial cells of nasal polyps (NP) and inferior turbinate (IT) were cultured without serum under stimulus of SEB 1, 10, 100 ng/ml, IL-1beta 20 ng/ml and SEB 10 ng/ml + dexamethasone 13 ng/ml for 12,24 and 48 h, respectively. The expression of IL-5 and Granulocyte-macrophage colony stimulating factor (GM-CSF) mRNA de... |
RESULTS |
(1) The expression of IL-5 and GM-CSF mRNA was time and dose-dependent, and reached to a peak under SEB 10 ng/ml for 24 h (P < 0.05). The mRNA expressed more intensively in epithelial cells from NP than IT (P < 0.05). (2) The expression of IL-5 and GM-CSF mRNA increased less under the stimulus of IL-1beta than SEB 10 n... |
CONCLUSION |
SEB showed proinflammatory effects on HNEC.Possibility Theory and Description Logics Based New Concept Extraction Approach |
The textual information volume is increasing rapidly. Searching for relevant information is becoming more and more difficult in this amount of information "Big Data". Knowledge representation and information extraction are fairly sensitive parts in the information retrieval field for the big databases. In this paper, w... |
Process Mining is an approach that uses event logs of systems or processes and turns them into valuable insights. The main characteristic of process mining techniques is that they focus on and exploit "real behavior" of a large number of stakeholders of a system or of a process. On the other hand, requirements engineer... |
ABSTRACT Through an empirical analysis of selected African countries for a period of 2006–2017, this paper explores three hypotheses suggesting that African entrepreneurship does not promote productivity except there are conducive institutional environments. The study applies panel data estimation techniques on data ob... |
Experiments have been conducted with backpropagation neural networks for Landsat thematic mapper (TM) image classification. Specifically, two nonparametric characteristics of the neural networks were tested. The first test demonstrated the flexibility of the networks by comparing the results from three classifications ... |
Different cell types, equipped with unique structure and function, synthesize different sets of proteins on the basis of different patterns of gene expression, even though their genomes are identical. Cardiac transcription factors have been reported to control a cardiac gene program and thus to play a crucial role in t... |
This paper presents the design issues, modeling, fabrication and characterization of a radome structure, a metamaterial cover over the slotted patch antenna for triband operation with center frequency 2.45 GHz. The dimensions of the slots patterned over the patch antenna are designed to control the lower resonant frequ... |
Abstract Metasurfaces have recently gained extensive interest because of their extraordinary optical behavior as artificial material interfaces with ultrahigh compactness. In this framework, dielectric platforms have newly become very promising for nonlinear nanophotonics, providing opportunities, especially for ultraf... |
The problem of fast exact and approximate searching for a pattern that contains classes of characters and bounded size gaps (CBG) in a text has a wide range of applications, among which a very important one is protein pattern matching (for instance, one PROSITE protein site is associated with the CBG [RK] - x(2,3) - [D... |
The tradition of herbal medication by plants and products of natural origin in the treatment of various diseasesexists thousands of years. Currently, despite the achievements of chemistry and biotechnology, the relevanceand popularity of the herbal medicine is quite high. The therapeutic effect peculiarity of the medic... |
The U.S. Army and the U.S. Air Force are investigating laser range-gated shortwave infrared (LRG-SWIR) imaging systems for use in target identification. When coupled to an electron-bombarded CCD, the imaging system can obtain high- resolution images at long ranges. Speckle, an image artifact inherent in laser illuminat... |
Corticosteroids are often administered prophylactically to attenuate the inflammatory response associated with cardiac surgery using cardiopulmonary bypass (CPB). However, the efficacy and safety profile of corticosteroids remain uncertain. The primary aim of this systematic review and meta-analysis was to investigate ... |
Abstract : This paper presents a unique research and development project conducted over the past four years by the George Mason University (GMU) Learning Agents Center (LAC) and the U.S. Army War College. This research synergistically integrates cutting edge artificial intelligence research, military strategy research,... |
Rotator cuff tear (RCT) and cervical spinal stenosis (CSS) are common pathologies in the elderly. Both conditions may present with lateral shoulder pain and weakness or numbness of the upper extremity, potentially affecting patients' ability to live independently. Few data are available on the incidence of CSS among pa... |
1. Marrow-iron stores were absent or reduced in twenty-three of thirty-nine patients studied within 52 months of starting maintenance haemodialysis. 2. Oral iron was given to twelve patients (group I) with absent or reduced, and to eleven patients (group II) with normal or increased marrow-iron stores. 3. A significant... |
Landslides represent great dangers that can cause fatalities and huge property damage. To prevent or reduce all possible consequences that landslides cause, it is necessary to know the kinematics of the surface and undersurface sliding masses. Geodetic surveying techniques can be used for landslide monitoring and creat... |
This paper 1 presents a rapid and robust parsing system currently used to learn from large bodies of unedited text. The system contains a multivalued part-of-speech disambiguator and a novel parser employing bottom-up recognition to nd the constituent phrases of larger structures that might be too diicult to analyze. T... |
Benzodiazepines (BZDs) are frequently used for insomnia, but the long-term use of BZDs is associated with adverse events such as dependence and withdrawal syndrome. Suvorexant (SUV), an orexin receptor antagonist, is a novel hyp-notic drug that has been shown to be effective for subjective measures of sleep onset and m... |
In this paper, a typical Li- and Ta/Sb- modified alkaline niobate-based ceramics are prepared by conventional sintering and two-step sintering respectively. The ceramics sintered by two-step sintering exhibit better electrical properties than the samples prepared by conventional sintering. The related mechanisms are al... |
BACKGROUND |
In view of the theoretical rationale for beneficial effects of DHEA and DHEAS in aging and dementia, we believe it is timely to undertake a thorough investigation of well-conducted studies in this area. This will provide a basis for confirmation of any effect of DHEA/S administration in humans, in large-scale and prope... |
OBJECTIVES |
To establish whether administration of DHEA, or its sulphate, DHEAS, improves psychological well-being and/or improves cognitive function or reduces the rate of decline of cognitive function in older adults or in individuals with dementia. |
SEARCH STRATEGY |
All available electronic databases, hand searched journals, personal communications and conference abstracts were searched for randomised controlled trials of DHEA in well-being and cognition. The total yield from searching was 415 and the detailed breakdown is given in the body of this review. |
SELECTION CRITERIA |
All relevant randomised controlled trials of DHEA or DHEAS were considered for inclusion in the review. Studies where groups are matched, rather than randomised, were also considered. |
DATA COLLECTION AND ANALYSIS |
Data for the specified outcomes were independently extracted by two reviewers (FAH & JvN) and cross-checked. Any discrepancies were discussed and resolved. Where possible and appropriate, data were pooled and the mean differences estimated. |
MAIN RESULTS |
The published DHEA trials fall into 2 categories: 1. four German studies in which DHEA was administered for a period of two weeks or less; 2. a USA study in which DHEA was administered for three months. Well-being was assessed in both sets of studies and a significant improvement was reported in the longer duration USA... |
REVIEWER'S CONCLUSIONS |
The data at present offer limited support for improvement in a sense of well-being following DHEA treatment. This effect was reported only in the longer-term study which used a crude measure of well-being. The data offer no support at present for an improvement in memory or other aspects of cognitive function following... |
Free crest spillways are hydraulically efficient and safe in operation. Since their discharge capacity is directly proportional to the crest length several types have been developed with the purpose to increase the length of the latter. Among these types traditional labyrinth weir spillways have been studied and used f... |
The difficult process of Copenhagen Meeting and the reaching of "Copenhagen agreement" without actual legal binding force, once again display that the intense competition for carbon credit and its necessity and urgency to promote low-carbon economy. With the implementation of low-carbon economy, some impact will be exe... |
This article discusses new approaches to communication studies, which integrates theory and practice of communication. The education environment is a prolific sphere of the study and implementation of new types and modes of communication in the digital space. The investigation considers the advantages of using podcasts... |
Fibromyalgia is a disorder bordering on rheumatology and psychiatry, which was included in the ICD-10 (M79.7) classification in the 1990s. It is characterised by a triad of symptoms including chronic widespread pain, sleep disturbances, and mental or physical exhaustion. According to various estimates, fibromyalgia aff... |
Prolonged antibiotic therapy is associated with antimicrobial resistance and increased mortality in preterm infants. We evaluated the impact of an automatic stop order (ASO) and C-reactive protein (CRP) on the duration of antibiotics and level of intervention in infants screened for early-onset sepsis who had negative ... |
Acoustic mapping of ocean currents with Distributed Networked Underwater Sensors (DNUS) system is an effective and energy-saving technique for monitoring oceanographic environments. Unlike the common acoustic tomography methods, this new approach can locally reconstruct ocean currents using data between neighboring sen... |
Repair of full-thickness defects of the lower eyelids poses a challenge because a graft in combination with a flap is typically used to replace either the posterior or the anterior lamella. This often results in aesthetically and functional unsatisfactory outcomes. A rotation-advancement tarsoconjunctival cheek flap, w... |
Erector spinae plane (ESP) block is an interfascial plane block where a local anaesthetic is injected in a plane preferably below the erector spinae muscle. It is supposed to work at the origin of spinal nerves based on cadaveric and contrast study. It has emerged as an effective and safe analgesic regional technique. ... |
The analysis of negative emotiogenic influence in dogs carried out according to dynamics of levels of acetylcholine and catecholamine content in peripheral blood and concomitant changes of the higher nervous activity, allows to conclude about the participation of both cholinergic and catecholaminergic neurotransmitter ... |
Quantum-behaved Particle Swarm Optimization (QPSO) is a new Particle Swarm Optimization (PSO) algorithm. Compared with Standard PSO (SPSO), it guarantees that particles converge in global optimum point in probability and this algorithm has better performance and stability. This paper introduces an improved Adaptive QPS... |
To study whether mounting an immune response is energetically costly, mice from two lines divergently selected for high (H-BMR) and low (L-BMR) basal metabolic rate (BMR) were immunized with sheep red blood cells. Their energy budgets were then additionally burdened by sudden transfer from an ambient temperature of 23 ... |
Spatial experience is an important subject in various fields, and in HCI it has been mostly investigated in the urban scale. Research on human scale spaces has focused mostly on the personal meaning or aesthetic and embodied experiences in the space. Further, spatial experience is increasingly topical in envisioning ho... |
[1] After reading this book one can only imagine that the author is a lively teacher of undergraduate philosophy students. Taking an idea and seeing where it goes is a wonderful teaching technique, sharpening our students’ abilities at critical thinking through ‘thought experiments’ [scare-quotes]. I am skeptical, howe... |
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