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RESULTS |
All dose groups of Maxy-G34 enrolled 6 pts each, except the 100 μg/kg group (3 pts), and the PF group (8 pts). The mean durations of G4N in cycle 1 were 2.2 days for 10 μg/kg, 1.8 days for 30 μg/kg, 0.8 days for 45 μg/kg, 2.2 days for 60 μg/kg, and 1.7 days for 100 μg/kg Maxy-G34 groups vs. 2.0 days for PF. The rate of... |
CONCLUSION |
Once-per-cycle Maxy-G34 appears to be effective in reducing CIN with no new safety signals. Further Phase II studies are planned. [Table: see text].Renal function in patients treated with tobramycin-cefuroxime or tobramycin-penicillin G. |
In order to evaluate the potentiating effect of cefuroxime on tobramycin nephrotoxicity 21 immunocompromised patients with suspected septicaemia were randomized to treatment with either tobramycin + cefuroxime or tobramycin + penicillin G. 51Chromium-EDTA clearance, serum creatinine, serum beta 2-microglobulin, urinary... |
The manner in which ' invisible hand' describes the self regulating behavior of the economic world, the concept of the Rule of Law also appears to stand for the self regulating behavior of the world of legal systems. In this sense, rule of law is an idea that is abstract at conceptual level but actual at impac t level.... |
Programmed cell death (PCD) is required for many aspects of plant biology, including stress responses, immunity, and plant development including root and flower development. Our understanding of PCD regulation is incomplete, especially concerning regulators involved in multiple divergent processes. The botrytis-susceti... |
A cooled multichannel detector has been developed that is based on a second-generation image intensifier tube and a Reticon photodiode array. The sensitivity of the device is characterized and discussed in terms of the limiting noise sources. For use in Raman spectroscopy, the detector has been optically matched to a t... |
: Sera collected from several migratory birds of the Danube Delta, from humans and domestic birds and animals of three Romanian counties were tested by hemagglutination-inhibition reaction for the presence of antibodies to Yaba 1--Lednice 110 virus. Antibodies could be detected in only 8 of the 14 species of migratory ... |
This book examines questions of identity, nationalism, and marginalization in the contemporary Egyptian novel from a postcolonial lens. Under colonial rule, the Egyptian novel invoked a sovereign nation-state by basking in its perceived unity. After independence, the novel professed disenchantment with state practices ... |
This study responds to the changing iconographic, semiotic, and formal features of the Egyptian novel. It fulfills the critical task of identifying an emergent novelistic genre and develops historically reflexive methodologies that interpret new-consciousness novels and their mediatory role in formalizing and articulat... |
OBJECTIVE |
To investigate differences in visual function, optic disc topography, and retinal nerve fiber layer (RNFL) thickness between healthy eyes of blacks and whites. |
METHODS |
Visual function was assessed in healthy eyes of 50 blacks and 50 whites using standard automated perimetry, short-wavelength automated perimetry, and frequency doubling technology perimetry. Optic disc topography and RNFL thickness were measured using the Heidelberg Retina Tomograph and the optical coherence tomograph. |
RESULTS |
Mean standard automated perimetry mean deviations were within the normal range for both groups. Blacks had worse mean deviation values than whites using frequency doubling technology perimetry (mean +/- SD, -1.8 +/- 3.2 dB vs -0.1 +/- 2.4 dB), blacks had larger optic disc areas than whites using the Heidelberg Retina T... |
CONCLUSIONS |
Minimal racial differences in visual function were found, but race significantly affected optic disc topography and superior and inferior RNFL thickness measurements in healthy eyes. The racial differences observed for intraocular pressure could theoretically increase after correcting for central corneal thickness. Pro... |
The spatial and temporal pattern of root water uptake in partially wetted soil was studied in the root zone of a six-year old micr o-sprinkler irrigated almond tree. The water balance of about one quarter of the root zone’s wetted soil volume (2.0 x 2.0 x 0.9 m) was determined by neutron probe and te nsiometer measurem... |
In some real-time applications, it is desirable to trade off precision for timeliness. For such systems, considered typically under the imprecise computation model, a function assigns reward to the application depending on the amount of computation allotted to it. Also, many such applications run on battery-powered dev... |
Introduction Homogeneous RF excitation and reception offers advantages for absolute quantification of metabolites, drugs and cells in vivo. Capecitabine is a drug taken orally for treatment of liver metastasis in colorectal cancer. It is a prodrug that is preferentially converted to active metabolites in tumor tissue a... |
Abstract This stud reports on the influence of indomethacin upon the renin‐angiotensin sstem in three patients with Bartter's sndrome. An analogue of angiotensin II with weak agonistic properties (suc‐cinam 11 ‐val5‐phenlglcine‐acetate8‐angiotensin II) induced a fall of blood pressure and a rise of plasma renin concent... |
Immunization is a cost-effective approach aimed at improving child survival. Coverage is an indicator to monitor the progress towards achieving child survival and the strategy to reduce childhood morbidity and mortality. The study was a descriptive cross-sectional study among 300 mothers /caregivers attending a tertia... |
Keywords: determinants, vaccination, tertiary hospital, childhoodIL-17A–Mediated Protection against Acanthamoeba Keratitis |
Acanthamoeba keratitis (AK) is a very painful and vision-impairing infection of the cornea that is difficult to treat. Although past studies have indicated a critical role of neutrophils and macrophages in AK, the relative contribution of the proinflammatory cytokine, IL-17A, that is essential for migration, activation... |
Background Janus kinase 3 (JAK3) plays a critical role in intracellular signal transduction and is required for activation of lymphocytes. Oral VX-509 selectively inhibits JAK3 and improves signs and symptoms in patients with active RA. Objectives To evaluate the pharmacodynamic effect of VX-509 on inflammatory biomark... |
Mobile applications have grown from knowing basic personal information to knowing intimate details of consumer's lives. The explosion of knowledge that applications contain and share can be contributed to many factors. Mobile devices are equipped with advanced sensors including GPS and cameras, while storing large amou... |
Undergraduate students should be able to manage their finances wisely while they are living apart from their parents. Therefore, good financial literacy and attitude should be developed during college to instil positive financial behaviour. It is a cross-country study to analyse the influence of financial literacy and ... |
When a product slips in status from “must have” to “don’t need,” it is generally tossed on the scrapheap of consumer history. Just ask the people who invented the floppy disk. According to some health experts, the foreskin is the floppy disk of the male anatomy, a once-important flap ofA Note on the Fibula Praenestina |
In a recent article published in this journal, Panhuis (1984, p. 148) attempts a brief discussion of the notorious Manios inscription on the so-called fibula praenestina (CIL. I 3): Manios med FheFhaked Numasioi. The inscription, which Panhuis says is "the oldest Latin text from ca. 600 B.C.", is presented as illustrat... |
The study of leisure is one of the most significant phenomena studied by sociology and other social sciences in recent decades. Leisure time can be defined as the time that a person has after fulfilling all his/her professional, familiar, social and physiological obligations, and creates it according to his/her own des... |
ided and .....e .....ere un able [0 dererrmne thc batches involved . '111e イ ゥ セ ォ of allergrc reacno ns (includ ing serum sickness) to snake a ntivenom ゥ セ mcreased by therecipienr 'sprevious exposure to horse serum .It is not reported .....hetherTankel's flnt patient had previously rec eived hon eserum-d erived prod ... |
In recent years, remarkable market competition and economy of scale has resulted in the price erosion of wireless devices for consumer electronics. Especially for wireless data networks, IEEE project 802 provides the standards for mass markets. With ever-growing usage, the demand for ubiquitous wireless networks increa... |
Local recurrence following curative resection for colorectal cancer may be caused by the seeding of free malignant cells at the anastigmatic site. This study investigated the influence of suture material on in vitro tumor cell adherence. Radiolabeled rat colonic cancer cells (RCC5) were incubated with a variety of sutu... |
In 2000 and 2001, a new disease was observed on commercial spinach (Spinacia oleracea) in the Salinas Valley, Monterey County, CA. Initial symptoms were water-soaked, irregularly shaped leaf spots (2 to 3 mm diameter). As the disease developed, spots enlarged to as much as 1 to 2 cm, were vein-delimited, and turned dar... |
In vitro rates of lactate conversion to glucose and oxidation to CO2 were determined in livers of stress-susceptible (SS) and stress-resistant (SR) pigs because we hypothesized that livers of SS pigs had a lower capacity than livers of SR pigs to remove lactate from blood. Stress-susceptibility was determined by reacti... |
Argyria is a rare cutaneous manifestation of silver deposits in the skin, characterized by a grayish blue discoloration, particularly in sun-exposed areas. We report the case of a patient with a history of schizoaffective disorder and type 2 diabetes mellitus who presented with argyria of the face and neck. The patient... |
We show that the value of corporate diversification increased during the 2007–2009 financial crisis. Diversification gave firms both financing and investment advantages. First, conglomerates became significantly more leveraged relative to comparable focused firms. Second, conglomerates’ access to internal capital marke... |
Plasma levels of fibrinogen, factor VIIc and prothrombin fragment F1 + 2, a marker of thrombin generation in vivo, were studied in 68 subjects with serum total cholesterol (TC) levels between 135 and 349 mg/dl but without clinical evidence of cardiovascular disease and other atherosclerotic risk factors. F1 + 2 plasma ... |
Fractional delay filters (FDFs) play an important role in certain areas of digital signal processing and communication engineering, where it is desirable to generate delays that are of the order of a fraction of the sampling period. In this paper, we advocate the use of generalized cardinal exponential splines-a class ... |
We investigate the adaptive tracking problem for the longitudinal dynamics of state-constrained airbreathing hypersonic vehicles, where not only the velocity and the altitude, but also the angle of attack (AOA) is required to be tracked. A novel indirect AOA tracking strategy is proposed by viewing the pitch angle as a... |
Outcomes of cardiopulmonary resuscitation (CPR) in hospitalized patients with ESRD requiring maintenance dialysis are unknown. Outcomes of in-hospital CPR in these patients were compared with outcomes in the general population using data from the Nationwide Inpatient Sample (NIS; 2005-2011). The study population includ... |
This paper describes a new low power analog model conceived for representing three-phase arc furnaces by means of uncontrolled rectifiers and heavy capacitive smoothing. The rest of the arc furnace installation is completed with LC elements taking into account power factor compensation and the effect of the arc furnace... |
In the current cluttered context, delivering brand communication competently to the intended target audience is a big challenge. Given the multiple options available in terms of brands and channels, creating the right impact is a tough call. One format which has emerged in recent times is long-duration storytelling. As... |
Prion diseases encompass a diverse group of neurodegenerative conditions characterized by the accumulation of misfolded prion protein (PrP) isoforms. Other conformational variants of PrP have also been proposed to contribute to neurotoxicity in prion diseases, including misfolded intermediates as well as cytosolic and ... |
: The paper studies and proposed an new effective methodology for the security threats involved in using modern smart phone for accessing Internet related services and various sources. Different types of materialised mobile malware are discussed in our previous works in order to classify them for further analysis. This... |
The accuracy factor of moving object in the monitoring system is very difficult. In today's world, human interception is essential to keep track of activities. To make it easy for the human, the technologies like Artificial Intelligence, Multi-sensor data fusion performs a crucial role in this system. The following pro... |
Jones, op. cit., especially Preface. 11. See B.H. Brown, The Tariff Reform Movement in Great Britain 1881-1895 (Columbia 1943); C.J. Fuchs, The Trade Policy of Britain and her Colonies Since 1860 (London 1905). 12. G.R. Searle, The Quest for National Efficiency (Oxford 1971). 13. Ibid., 54. 14. See Royal Commission on ... |
Previous studies have illustrated the importance of T cells bearing alpha beta TCRs in the induction and development of collagen induced arthritis (CIA) in mice. However, the scope of TCR usage in CIA has yet to be clearly defined. Given the inherent diversity of the TCR repertoire, the relative flexibility of the arth... |
MOTIVATION |
One important requirement for protein design is to be able to predict changes of protein stability upon mutation. Different methods addressing this task have been described and their performance tested considering global linear correlation between predicted and experimental data. Neither is direct statistical evaluatio... |
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