text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
[ comparative analysis of the blood sugar ( by continuous recording ) and of portal and peripheral blood insulin after glucose loading by means of duodenal catheterization in anesthetized dogs ] . | NA | {
"id": "C0005802",
"name": "blood sugar",
"pos": [
30,
41
]
} | {
"id": "C0017725",
"name": "glucose",
"pos": [
119,
126
]
} |
thiamine , thiamine monophosphate , and thiamine pyrophosphate were all equally active for the parent , whereas mutants 70-23-102 and 70-23-107 lost their ability to grow on thiamine . | NA | {
"id": "C0039845",
"name": "thiamine monophosphate",
"pos": [
11,
33
]
} | {
"id": "C0039840",
"name": "thiamine",
"pos": [
174,
182
]
} |
exogenous thiamine , on the other hand , is converted to thiamine pyrophosphate via the intermediate formation of thiamine monophosphate . | NA | {
"id": "C0039840",
"name": "thiamine",
"pos": [
10,
18
]
} | {
"id": "C0039845",
"name": "thiamine monophosphate",
"pos": [
114,
136
]
} |
an escherichia coli mutant dependent on exogenous transfer ribonucleic acid ( rna ) for bulk rna formation at 42 c has been isolated , starting from a parental strain permeable to rna . | NA | {
"id": "C0035711",
"name": "transfer ribonucleic acid",
"pos": [
50,
75
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
180,
183
]
} |
alkaline sucrose gradient centrifugation revealed occurrence of single-strand incision of uv-irradiated dna and the restitution of nicked dna at a similar rate in the recb21 res-1 and recb21 res ( + ) strains . | NA | {
"id": "C0012935",
"name": "single-strand",
"pos": [
64,
77
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
138,
141
]
} |
few free fatty acids and no non-extractable fatty acids associated with the cell wall or membrane were found . | NA | {
"id": "C0015688",
"name": "free fatty acids",
"pos": [
4,
20
]
} | {
"id": "C0015684",
"name": "fatty acids",
"pos": [
44,
55
]
} |
although the beta-glucoside kinase was previously shown to catalyze the phosphorylation of many beta-glucosides that serve as growth substrates ( i.e. , gentiobiose , cellobiose , cellobiitol , salicin , arbutin , methyl beta-d-glucoside , and phenyl beta-d-glucoside ) , mutant analysis and induction studies indicate t... | NA | {
"id": "C0017765",
"name": "glucosides",
"pos": [
101,
111
]
} | {
"id": "C0003729",
"name": "arbutin",
"pos": [
204,
211
]
} |
chloroethylthiamine was found to inhibit an entrapment of thiamine as thiamine monophosphate by blocking thiamine monophosphokinase in the cytoplasm after thiamine was taken up by the cells of escherichia coli . | NA | {
"id": "C0039845",
"name": "thiamine",
"pos": [
11,
19
]
} | {
"id": "C0039840",
"name": "thiamine",
"pos": [
155,
163
]
} |
the method detected antibody of both the immunoglobulin m and immunoglobulin g class when quantitated after ultracentrifugation and sucrose density gradient separation . | NA | {
"id": "C0003241",
"name": "antibody",
"pos": [
20,
28
]
} | {
"id": "C0021017",
"name": "immunoglobulin",
"pos": [
62,
76
]
} |
the method detected antibody of both the immunoglobulin m and immunoglobulin g class when quantitated after ultracentrifugation and sucrose density gradient separation . | NA | {
"id": "C0020861",
"name": "immunoglobulin m",
"pos": [
41,
57
]
} | {
"id": "C0021017",
"name": "immunoglobulin",
"pos": [
62,
76
]
} |
t-2 toxin ( 3-hydroxy-4 , 15-diacetoxy-8- [ 3-methylbutyryloxy ] -12 , 13-epoxy-delta ( 9 ) -trichothecene ) at concentrations of 2 mg per kg of dry corn was identified in purified extracts of the moldy corn by means of gas-liquid chromatography and mass spectrometry . | NA | {
"id": "C0039185",
"name": "t-2 toxin",
"pos": [
0,
9
]
} | {
"id": "C0040952",
"name": "trichothecene",
"pos": [
93,
106
]
} |
indirect hemagglutination ( iha ) antigen titers in 229e-infected cell cultures paralleled virus infectivity and complement fixation ( cf ) antigen titers . | NA | {
"id": "C0003342",
"name": "antigen",
"pos": [
34,
41
]
} | {
"id": "C0003320",
"name": "antigen",
"pos": [
140,
147
]
} |
when newcastle disease virus was used as the inducer , fibroblasts and amnion cells produced more interferon per 10 ( 6 ) cells than leukocytes , lymphoid cells , and heteroploid cells . | NA | {
"id": "C0016030",
"name": "fibroblasts",
"pos": [
55,
66
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
179,
184
]
} |
several other phenylurea compounds ( chloroxuron , diuron , fenuron , fluometuron , linuron , metobromuron , neburon , and siduron ) were also metabolized by the fungus , indicating that r. solani may possess a generalized ability to attack this group of herbicides . | NA | {
"id": "C0031506",
"name": "phenylurea compounds",
"pos": [
14,
34
]
} | {
"id": "C0012804",
"name": "diuron",
"pos": [
51,
57
]
} |
several other phenylurea compounds ( chloroxuron , diuron , fenuron , fluometuron , linuron , metobromuron , neburon , and siduron ) were also metabolized by the fungus , indicating that r. solani may possess a generalized ability to attack this group of herbicides . | NA | {
"id": "C0031506",
"name": "phenylurea compounds",
"pos": [
14,
34
]
} | {
"id": "C0023755",
"name": "linuron",
"pos": [
84,
91
]
} |
anion diffusion across artificial lipid membranes : the effects of lysozyme on anion diffusion from phospholipid liposomes . | NA | {
"id": "C0025256",
"name": "artificial",
"pos": [
23,
33
]
} | {
"id": "C0023828",
"name": "liposomes",
"pos": [
113,
122
]
} |
reconstitution of a calcium pump with phospholipids and a purified ca ++ - adenosine triphosphatase from sacroplasmic reticulum . | NA | {
"id": "C0001476",
"name": "calcium pump",
"pos": [
20,
32
]
} | {
"id": "C0001473",
"name": "adenosine triphosphatase",
"pos": [
75,
99
]
} |
however , in indian women with gallstones , secretion of biliary cholesterol was also significantly increased , as compared with caucasian women without stones . | NA | {
"id": "C0008350",
"name": "gallstones",
"pos": [
31,
41
]
} | {
"id": "C0006736",
"name": "stones",
"pos": [
153,
159
]
} |
ffa oxidation could not be measured at rest but exercise data showed a lower fractional oxidation of ffa ( p < 0.001 ) in the patient group ( 53+/-6 % ) compared with the controls ( 84+/-2 % ) . | NA | {
"id": "C0015688",
"name": "ffa",
"pos": [
0,
3
]
} | {
"id": "C0015684",
"name": "ffa",
"pos": [
101,
104
]
} |
when six patients were studied after reconstructive surgery , fractional oxidation of ffa had risen from a preoperative value of 47+/-8 to 90+/-10 % , other data for leg muscle ffa metabolism being unchanged . | NA | {
"id": "C0015684",
"name": "ffa",
"pos": [
86,
89
]
} | {
"id": "C0015688",
"name": "ffa",
"pos": [
177,
180
]
} |
calcitonin resistance : clinical and immunologic studies in subjects with paget 's disease of bone treated with porcine and salmon calcitonins . | NA | {
"id": "C0006668",
"name": "calcitonin",
"pos": [
0,
10
]
} | {
"id": "C0073994",
"name": "salmon calcitonins",
"pos": [
124,
142
]
} |
however , in patients with target cells the amount of cholic and deoxycholic acids in serum was approximately equal to the amount of chenodeoxycholic acid , whereas in patients with spur cells chenodeoxycholic acid ( the precursor of lithocholic acid ) predominated . | NA | {
"id": "C0011479",
"name": "deoxycholic acids",
"pos": [
65,
82
]
} | {
"id": "C0008024",
"name": "chenodeoxycholic acid",
"pos": [
193,
214
]
} |
[ xyy syndrome and trisomy 21 ( 48 , xyy , 21+ ) . a phenotype showing a combined autosomal and gonosomal chromosome aberrations ] . | NA | {
"id": "C3266843",
"name": "xyy syndrome",
"pos": [
2,
14
]
} | {
"id": "C0036868",
"name": "gonosomal",
"pos": [
96,
105
]
} |
[ clinical application of prostaglandin f2a ( p.g.f2a ) as a drug which can produce an interruption of pregnancy during the 1st trimester ] . | NA | {
"id": "C0032961",
"name": "pregnancy",
"pos": [
103,
112
]
} | {
"id": "C0032979",
"name": "1st trimester",
"pos": [
124,
137
]
} |
incubation resulted in a net loss of erythrocyte cholesterol and , simultaneously , in an increase of esterified cholesterol in plasma and alpha-lipoproteins . | NA | {
"id": "C0008377",
"name": "cholesterol",
"pos": [
49,
60
]
} | {
"id": "C0008387",
"name": "esterified cholesterol",
"pos": [
102,
124
]
} |
particles in the size range of chylomicrons , uncontaminated by lipoproteins smaller than about 700 a or by other serum proteins , emerged in the void volume of the column , and very low density lipoproteins with diameters between 400 and 700 a were separated into fractions with average standard deviation of 71 a from ... | NA | {
"id": "C0008731",
"name": "chylomicrons",
"pos": [
31,
43
]
} | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
195,
207
]
} |
particles in the size range of chylomicrons , uncontaminated by lipoproteins smaller than about 700 a or by other serum proteins , emerged in the void volume of the column , and very low density lipoproteins with diameters between 400 and 700 a were separated into fractions with average standard deviation of 71 a from ... | NA | {
"id": "C0023820",
"name": "lipoproteins",
"pos": [
64,
76
]
} | {
"id": "C0023825",
"name": "very low",
"pos": [
178,
186
]
} |
in hematoside there were also measurable amounts of c ( 18 ) -sphinganine and c ( 20 ) -sphinganine , whereas in the major gangliosides only traces of c ( 18 ) -sphinganine were detected . | NA | {
"id": "C0016897",
"name": "hematoside",
"pos": [
3,
13
]
} | {
"id": "C0017082",
"name": "gangliosides",
"pos": [
123,
135
]
} |
immune cells induced by bovine serum albumin ( bsa ) and its methylated derivative ( mbsa ) have been compared in a cooperative cell transfer system for their content of bsa-specific antibody-forming cell precursors ( afcp , b ) and bsa-specific helper ( t ) cells . | NA | {
"id": "C0007634",
"name": "cell",
"pos": [
7,
11
]
} | {
"id": "C0018956",
"name": "cell precursors",
"pos": [
200,
215
]
} |
the effect of l-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo . | NA | {
"id": "C0041249",
"name": "tryptophan",
"pos": [
16,
26
]
} | {
"id": "C0000578",
"name": "hydroxytryptophan",
"pos": [
77,
94
]
} |
the effects of 6-hydroxydopamine pretreatment on the accumulation of dopa and dopamine in brain and peripheral organs following l-dopa administration . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
24,
28
]
} | {
"id": "C0023570",
"name": "l-dopa",
"pos": [
128,
134
]
} |
[ the relationship between the weight of the fetus , the weight and surface area of the placenta and the structure of the veins of the fetal surface of the placenta ] . | NA | {
"id": "C0751992",
"name": "weight",
"pos": [
31,
37
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
57,
63
]
} |
in addition to two factors present which are known to moderate the clinical course of sickle-cell anaemia , good socioeconomic status and a relatively high hb f level , it is suggested that alpha-thalassaemia may act among other things by lowering the haemoglobin concentration in the red cells and thereby lowering thei... | NA | {
"id": "C0015936",
"name": "hb f",
"pos": [
156,
160
]
} | {
"id": "C0019046",
"name": "haemoglobin",
"pos": [
252,
263
]
} |
sjogren 's syndrome is a common accompaniment of rheumatoid arthritis and other connective-tissue diseases as well as several diseases thought to have an immunological basis . | NA | {
"id": "C1527336",
"name": "sjogren 's syndrome",
"pos": [
0,
19
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
49,
69
]
} |
[ adenine nucleotides , nad + and nadh in skeletal muscles during intensive work and in rest periods ] . | NA | {
"id": "C0001413",
"name": "adenine nucleotides",
"pos": [
2,
21
]
} | {
"id": "C0027270",
"name": "nad",
"pos": [
34,
37
]
} |
the sucrose acts as substrate for an active beta-fructofuranosidase , produced by the fungus , which in the first instance converts the disaccharide into glucose and an oligofructoside . | NA | {
"id": "C0038636",
"name": "sucrose",
"pos": [
4,
11
]
} | {
"id": "C0012611",
"name": "disaccharide",
"pos": [
136,
148
]
} |
the enzyme-catalysed exchange of the methyl hydrogen atoms of the ; virtual substrate ' monohydroxyacetone phosphate with solvent ( 2 ) h ( 2 ) o or ( 3 ) h ( 2 ) o was shown . | NA | {
"id": "C0020275",
"name": "hydrogen",
"pos": [
44,
52
]
} | {
"id": "C0011744",
"name": "h ( 2",
"pos": [
136,
141
]
} |
a reinvestigation of the behaviour of rat brain 15000g supernatant guanine deaminase isoenzymes revealed that one enzyme had sigmoidal kinetics and the other enzyme showed a hyperbolic response . | NA | {
"id": "C0022173",
"name": "isoenzymes",
"pos": [
85,
95
]
} | {
"id": "C0014442",
"name": "enzyme",
"pos": [
158,
164
]
} |
acrolein was determined by condensation of the distilled aldehyde with semicarbazide , followed by spectrophotometric measurement of the semicarbazone at 257nm and identification by paper chromatography . | NA | {
"id": "C0001204",
"name": "acrolein",
"pos": [
0,
8
]
} | {
"id": "C0001992",
"name": "aldehyde",
"pos": [
57,
65
]
} |
spermidine-stimulated s-adenosyl-l-methionine decarboxylase has an apparent half-life of 60min , identical with the half-life reported for putrescine-stimulated s-adenosyl-l-methionine decarboxylase . | NA | {
"id": "C0037871",
"name": "stimulated",
"pos": [
11,
21
]
} | {
"id": "C0034170",
"name": "putrescine",
"pos": [
139,
149
]
} |
the purified c ( 1 ) component had little ability to attack cm-cellulose or highly ordered forms of cellulose , but degraded phosphoric acid-swollen cellulose readily : cellobiose was the principal product of the hydrolysis ( 97 % ) . | NA | {
"id": "C0007648",
"name": "cellulose",
"pos": [
63,
72
]
} | {
"id": "C0007630",
"name": "cellobiose",
"pos": [
169,
179
]
} |
acid nuclear proteins differ from the histones in incorporating labelled amino acids and ( 32 ) p fairly constantly through the cell cycle . | NA | {
"id": "C0028589",
"name": "nuclear",
"pos": [
5,
12
]
} | {
"id": "C0019652",
"name": "histones",
"pos": [
38,
46
]
} |
( 1 ) pyrrolidonecarboxyl-trna was not found in incorporation experiments with rat liver preparations and [ u- ( 14 ) c ] -pyrrolidonecarboxylic acid , glutamic acid and glutamine , even though an incorporation extent of less than 2 % of the total products could have been detected . | NA | {
"id": "C0061472",
"name": "glutamic acid",
"pos": [
152,
165
]
} | {
"id": "C0017797",
"name": "glutamine",
"pos": [
170,
179
]
} |
the dna is composed of three main classes of dna , as defined by their buoyant density , rho , in cscl : a bulk dna , rho = 1.699 g cm ( -3 ) , and two satellite dnas , rho = 1.685 g cm ( -3 ) and rho = 1.669 g cm ( -3 ) . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
4,
7
]
} | {
"id": "C0012934",
"name": "satellite dnas",
"pos": [
152,
166
]
} |
the satellite dna 's from five drosophila species ( d. melanogaster , d. simulans , d. nasuta , d. virilis and d. hydei ) were analyzed and found to fall into three arbitrary cscl buoyant density classes : class i , rho = 1.661-1.669 g cm ( -3 ) , dna molecules composed of primarily da and dt moieties ; | NA | {
"id": "C0012934",
"name": "satellite dna 's",
"pos": [
4,
20
]
} | {
"id": "C0012854",
"name": "dna molecules",
"pos": [
248,
261
]
} |
[ spray drying agglomeration . 3. angle of repose and cohesive force of agglomerated salicylic acid and sodium salicylate particles ] . | NA | {
"id": "C0036079",
"name": "salicylic acid",
"pos": [
85,
99
]
} | {
"id": "C0037549",
"name": "sodium salicylate",
"pos": [
104,
121
]
} |
tissue distribution of labelled material in vitamin c-deficient guinea pigs after intravenous injection of 1- 14 c ) ascorbic acid or ( 1- 14 c ) dehydroascorbic acid . | NA | {
"id": "C0003968",
"name": "ascorbic acid",
"pos": [
117,
130
]
} | {
"id": "C0011177",
"name": "dehydroascorbic acid",
"pos": [
146,
166
]
} |
the difference in the abilities of cytoplasmic and nuclear rna to inhibit the hybridization of virus-specific rna from whole cells was shown not to be due to a difference in the molecular size of the rna species from the two cell fractions or to the specific loss of a cytoplasmic species during rna extraction procedure... | NA | {
"id": "C0035700",
"name": "nuclear rna",
"pos": [
51,
62
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
296,
299
]
} |
a 1.1-mg amount of viral rna was prepared from 17.7 mg of polysomal rna that had been purified by extraction at ph 9.0 . | NA | {
"id": "C0035736",
"name": "viral rna",
"pos": [
19,
28
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
68,
71
]
} |
rna-dna hybridization was used to show that host messenger rna synthesis continues late into the phage lytic cycle . | NA | {
"id": "C0035668",
"name": "rna",
"pos": [
0,
3
]
} | {
"id": "C0035696",
"name": "messenger rna",
"pos": [
49,
62
]
} |
it binds tightly and cooperatively to single-stranded dna , and much less tightly , if at all , to rna or double-stranded dna . | NA | {
"id": "C0012935",
"name": "single-stranded dna",
"pos": [
38,
57
]
} | {
"id": "C0012854",
"name": "double-stranded dna",
"pos": [
106,
125
]
} |
the data indicate that : ( i ) collagen is secreted as a disulfidestabilized procollagen trimer with the composition , ( pro alpha1 ) ( 2 ) .pro alpha2 ; | NA | {
"id": "C0009325",
"name": "collagen",
"pos": [
31,
39
]
} | {
"id": "C0033235",
"name": "procollagen",
"pos": [
77,
88
]
} |
in vitro assembly of tobacco mosaic virus ( tmv ) from its constituent rna and protein occurs in two steps : formation of the initial complex by interaction of the 5'-end of tmv-rna with 20s protein aggregate , and growth of the helical rod by sequential addition of protein subunits . | NA | {
"id": "C0033684",
"name": "protein",
"pos": [
79,
86
]
} | {
"id": "C0599220",
"name": "protein subunits",
"pos": [
267,
283
]
} |
the purified enzyme degraded insulin but not proinsulin , with a k ( m ) for insulin of 22 nm and a k ( i ) for proinsulin of 40 nm . | NA | {
"id": "C0021641",
"name": "insulin",
"pos": [
29,
36
]
} | {
"id": "C0033362",
"name": "proinsulin",
"pos": [
112,
122
]
} |
new 5-hydroxy- and 5-chloro-6-alkyl-1,4-benzoquinones with one or two methyl groups on the nucleus were synthesized as potential antimetabolites of plastoquinones for biological research on photosynthetic and mammalian enzyme systems ; | NA | {
"id": "C0079017",
"name": "benzoquinones",
"pos": [
40,
53
]
} | {
"id": "C0032169",
"name": "plastoquinones",
"pos": [
148,
162
]
} |
above ph 7 , and in the temperature range 303-323 degrees k , ion-diffusion potentials created by salts of monovalent cations showed that areas of the membrane activated by excitation-inducing material were only permeable to cations . | NA | {
"id": "C0022023",
"name": "ion",
"pos": [
62,
65
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
225,
232
]
} |
above ph 7 , and in the temperature range 303-323 degrees k , ion-diffusion potentials created by salts of monovalent cations showed that areas of the membrane activated by excitation-inducing material were only permeable to cations . | NA | {
"id": "C0007449",
"name": "monovalent cations",
"pos": [
107,
125
]
} | {
"id": "C0007447",
"name": "cations",
"pos": [
225,
232
]
} |
antibodies reactive with distinct regions of the staphylococcal nuclease molecule were prepared both by immunization with polypeptide fragments of nuclease and by immunization with intact nuclease followed by fractionation of the antiserum on immuno-absorbent columns bearing the corresponding fragments . | NA | {
"id": "C0003241",
"name": "antibodies",
"pos": [
0,
10
]
} | {
"id": "C0020960",
"name": "antiserum",
"pos": [
230,
239
]
} |
[ serum cholinesterase synthesis in children with liver diseases with special reference to acute icteric and anicteric hepatitis ] . | NA | {
"id": "C0023895",
"name": "liver diseases",
"pos": [
50,
64
]
} | {
"id": "C0019158",
"name": "hepatitis",
"pos": [
119,
128
]
} |
[ systematic research on mycoses . results and considerations on a large and systematic epidemiologic survey of histoplasmosis in the region of lombardy and venetia ] . | NA | {
"id": "C0026946",
"name": "mycoses",
"pos": [
25,
32
]
} | {
"id": "C0019655",
"name": "histoplasmosis",
"pos": [
112,
126
]
} |
[ treatment of pseudarthroses and ununited fractures , complicated by purulent infection , by the method of compression-distraction osteosynthesis ] . | NA | {
"id": "C0033785",
"name": "pseudarthroses",
"pos": [
15,
29
]
} | {
"id": "C0016665",
"name": "ununited fractures",
"pos": [
34,
52
]
} |
[ infection and microflora during extrafocal compression osteosynthesis in ununited fractures and pseudarthroses complicated by osteomyelitis ] . | NA | {
"id": "C0016665",
"name": "ununited fractures",
"pos": [
75,
93
]
} | {
"id": "C0033785",
"name": "pseudarthroses",
"pos": [
98,
112
]
} |
inhalation of a new anticholinergic drug , sch 1000 , in asthma and chronic bronchitis : effect on airway resistance , thoracic gas volume , blood gases and exercise-induced asthma . | NA | {
"id": "C0004096",
"name": "asthma",
"pos": [
57,
63
]
} | {
"id": "C0004099",
"name": "exercise-induced asthma",
"pos": [
157,
180
]
} |
[ effect of dopa and tyrosine on catecholamine metabolism upon electric stimulation of the sciatic nerve in rats ] . | NA | {
"id": "C0013023",
"name": "dopa",
"pos": [
12,
16
]
} | {
"id": "C0007412",
"name": "catecholamine",
"pos": [
33,
46
]
} |
effects of metopirone on urinary excretion of adrenaline , noradrenaline and vanylmandelic acid in different physiological conditions . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
46,
56
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
59,
72
]
} |
effects of vitamin k and naphthoquinones on lipid peroxide formation and oxidative demethylation by liver microsomes . | NA | {
"id": "C0042878",
"name": "vitamin k",
"pos": [
11,
20
]
} | {
"id": "C0027388",
"name": "naphthoquinones",
"pos": [
25,
40
]
} |
an ; in-vitro ' technique is described for measuring quantitatively the absorption and secretion of water and electrolytes , the short circuiting current , and the simultaneous bidirectional flux rates of ions across the healthy and diseased colonic mucosa . | NA | {
"id": "C0013832",
"name": "electrolytes",
"pos": [
110,
122
]
} | {
"id": "C0022023",
"name": "ions",
"pos": [
205,
209
]
} |
replacement of mucosal sodium chloride by potassium chloride or lithium chloride had little effect on potentials , but its replacement by mannitol or tris chloride increased the negativity of the mucosal potential , giving linear relationships against log ( 10 ) [ na ] ( m ) with slopes of 41.4 and 30.7 mv respectively... | NA | {
"id": "C0037494",
"name": "sodium chloride",
"pos": [
23,
38
]
} | {
"id": "C0008203",
"name": "chloride",
"pos": [
155,
163
]
} |
replacement of mucosal sodium chloride by potassium chloride or lithium chloride had little effect on potentials , but its replacement by mannitol or tris chloride increased the negativity of the mucosal potential , giving linear relationships against log ( 10 ) [ na ] ( m ) with slopes of 41.4 and 30.7 mv respectively... | NA | {
"id": "C0032825",
"name": "potassium chloride",
"pos": [
42,
60
]
} | {
"id": "C0008203",
"name": "chloride",
"pos": [
155,
163
]
} |
replacement of mucosal sodium chloride by potassium chloride or lithium chloride had little effect on potentials , but its replacement by mannitol or tris chloride increased the negativity of the mucosal potential , giving linear relationships against log ( 10 ) [ na ] ( m ) with slopes of 41.4 and 30.7 mv respectively... | NA | {
"id": "C0065088",
"name": "lithium chloride",
"pos": [
64,
80
]
} | {
"id": "C0008203",
"name": "chloride",
"pos": [
155,
163
]
} |
during recovery , even though new proteoglycans were formed , they were nevertheless of smaller size and lower chondroitin sulphate content than control proteoglycans . | NA | {
"id": "C0033692",
"name": "proteoglycans",
"pos": [
34,
47
]
} | {
"id": "C0033689",
"name": "chondroitin sulphate",
"pos": [
111,
131
]
} |
the rna of the blue-green alga anacystis nidulans contains three ribosomal rna species with molecular weights of 0.56x10 ( 6 ) , 0.9x10 ( 6 ) , and 1.1x10 ( 6 ) if the rna is extracted in the absence of mg ( 2+ ) . | NA | {
"id": "C0035701",
"name": "ribosomal rna",
"pos": [
65,
78
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
168,
171
]
} |
the molecular weights of enzyme , inhibitor and enzyme-inhibitor complex , determined by gel filtration are about 23500 , 15000 and 35000 respectively . | NA | {
"id": "C0014442",
"name": "enzyme",
"pos": [
25,
31
]
} | {
"id": "C0026741",
"name": "enzyme",
"pos": [
48,
54
]
} |
2-bromopalmitoyl-coa , added as such or formed from 2-bromopalmitate , inhibits the carnitine-dependent oxidation of palmitate or palmitoyl-coa , but not the oxidation of palmitoylcarnitine , by intact liver mitochondria . | NA | {
"id": "C0007258",
"name": "carnitine",
"pos": [
84,
93
]
} | {
"id": "C0030242",
"name": "palmitoylcarnitine",
"pos": [
171,
189
]
} |
however , the oxidation of these substrates ( but not of palmitate , palmitoyl-coa or palmitoyl-carnitine ) is restored by carnitine . | NA | {
"id": "C0030242",
"name": "palmitoyl-carnitine",
"pos": [
86,
105
]
} | {
"id": "C0007258",
"name": "carnitine",
"pos": [
123,
132
]
} |
behaviour of adenine nucleotides during the platelet release reaction induced by adenosine diphosphate and adrenaline . | NA | {
"id": "C0001413",
"name": "adenine nucleotides",
"pos": [
13,
32
]
} | {
"id": "C0001459",
"name": "adenosine diphosphate",
"pos": [
81,
102
]
} |
analysis of the rates and amounts of rrna and 5s rna synthesized in drosophila melanogaster bobbed mutants was done by using acrylamide-gel electrophoresis . | NA | {
"id": "C0035701",
"name": "rrna",
"pos": [
37,
41
]
} | {
"id": "C0035668",
"name": "rna",
"pos": [
49,
52
]
} |
the passive protection of mice against an intracerebral infection with bordetella pertussis , by antiserum introduced directly into the brain with the infecting organisms , was compared with the protection afforded by intraperitoneal antiserum . | NA | {
"id": "C0006015",
"name": "infection",
"pos": [
56,
65
]
} | {
"id": "C0043167",
"name": "pertussis",
"pos": [
82,
91
]
} |
too much antiserum given intracerebrally with a 50,000 challenge , but not with a 5000 challenge , inhibits protection.in some mice , virulent antibody-treated organisms which have not been killed , grow very slowly over a long period , but are eventually eliminated from the brain . | NA | {
"id": "C0020960",
"name": "antiserum",
"pos": [
9,
18
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
143,
151
]
} |
these results were confirmed by inhibition tests with specific antisera and by elution of the antibody from agglutinated rbpt antigen . | NA | {
"id": "C0020960",
"name": "antisera",
"pos": [
63,
71
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
94,
102
]
} |
[ symposium on amyloidosis among the japanese . 3. familial primary amyloidosis with nervous system involvement among the japanese ] . | NA | {
"id": "C0002726",
"name": "amyloidosis",
"pos": [
15,
26
]
} | {
"id": "C0740340",
"name": "familial",
"pos": [
51,
59
]
} |
the dibutyryl derivative of guanosine 3 ' 5'-monophosphate caused a depolarization of the postganglionic neurons , which is consistent with the possibility that guanosine 3 ' 5'-monophosphate mediates synaptic transmission at muscarinic cholinergic synapses . | NA | {
"id": "C0012055",
"name": "dibutyryl",
"pos": [
4,
13
]
} | {
"id": "C0018338",
"name": "guanosine",
"pos": [
161,
170
]
} |
[ seasonal changes in the content of catecholamines and dopa in tissues of the carp cyrpinus carpio ] . | NA | {
"id": "C0007412",
"name": "catecholamines",
"pos": [
37,
51
]
} | {
"id": "C0013023",
"name": "dopa",
"pos": [
56,
60
]
} |
formation in agar of fibroblast-like colonies by cells from the mouse pleural cavity and other sources . | NA | {
"id": "C0016030",
"name": "fibroblast",
"pos": [
21,
31
]
} | {
"id": "C0007634",
"name": "cells",
"pos": [
49,
54
]
} |
assembly of the nucleoprotein rods of tobacco mosaic virus from the protein disks and rna . | NA | {
"id": "C0028612",
"name": "nucleoprotein",
"pos": [
16,
29
]
} | {
"id": "C0033684",
"name": "protein",
"pos": [
68,
75
]
} |
growth on a deficient medium was promoted by sulphonamides and nitrofurantoin as well as by para-amino benzoic acid , para-amino salicylic acid , procaine hydrochloride , thymine , and uracil . | NA | {
"id": "C0040087",
"name": "thymine",
"pos": [
171,
178
]
} | {
"id": "C0041917",
"name": "uracil",
"pos": [
185,
191
]
} |
[ analysis of the wax ester fraction of skin surface lipids in acne vulgaris using gas chromatography ] . | NA | {
"id": "C0043076",
"name": "wax",
"pos": [
18,
21
]
} | {
"id": "C0023779",
"name": "lipids",
"pos": [
53,
59
]
} |
[ effect of vitamin a acid ( vaa ) on psoriasis . topical combined therapy using corticoids . two new vaa preparations for oral administration ] . | NA | {
"id": "C0040845",
"name": "vitamin a acid",
"pos": [
12,
26
]
} | {
"id": "C0042839",
"name": "vaa preparations",
"pos": [
102,
118
]
} |
the agonists isoprenaline , adrenaline , noradrenaline and phenylephrine produced an inhibition of the post-partum rat uterus.3 . | NA | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
28,
38
]
} | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
41,
54
]
} |
in the presence of propranolol , the agonists noradrenaline , adrenaline , and phenylephrine had an excitatory effect on the post-partum rat uterus . | NA | {
"id": "C0028351",
"name": "noradrenaline",
"pos": [
46,
59
]
} | {
"id": "C0014563",
"name": "adrenaline",
"pos": [
62,
72
]
} |
at 2 days after infection there appeared viral dna sequences cosedimenting with cellular dna during alkaline velocity centrifugation . | NA | {
"id": "C0012939",
"name": "viral",
"pos": [
41,
46
]
} | {
"id": "C0012854",
"name": "dna",
"pos": [
89,
92
]
} |
integration of sv40 dna into cellular dna did not appear to require dna synthesis , although dna synthesis followed by mitotic division of the cells enhanced the amount of viral dna integrated . | NA | {
"id": "C0012854",
"name": "dna",
"pos": [
20,
23
]
} | {
"id": "C0012939",
"name": "viral",
"pos": [
172,
177
]
} |
the difference is due to the presence in the unabsorbed antiserum of antibodies to cellular proteins that are present in purified virus preparations . | NA | {
"id": "C0020960",
"name": "antiserum",
"pos": [
56,
65
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
69,
79
]
} |
they could synthesize only phosphatidic acid and diphosphatidylglycerol from a [ ( 32 ) p ] p ( i ) precursor and not nitrogen-containing phosphoglycerides or phosphatidylinositol . | NA | {
"id": "C0162448",
"name": "phosphoglycerides",
"pos": [
138,
155
]
} | {
"id": "C0031621",
"name": "phosphatidylinositol",
"pos": [
159,
179
]
} |
on the intraperitoneal injection of [ ( 32 ) p ] p ( i ) into guinea pigs , incorporation of radioactivity into phosphatidylinositol and phosphatidic acid was much faster than into the nitrogen-containing phosphoglycerides . | NA | {
"id": "C0031621",
"name": "phosphatidylinositol",
"pos": [
112,
132
]
} | {
"id": "C0162448",
"name": "phosphoglycerides",
"pos": [
205,
222
]
} |
( 32 ) p-labelled microsomes could slowly donate phospholipid to the isolated synaptosomal ( nerve-ending ) fraction but the phospholipids of the myelin fraction did not exchange . | NA | {
"id": "C0031676",
"name": "phospholipid",
"pos": [
49,
61
]
} | {
"id": "C0771648",
"name": "phospholipids of",
"pos": [
125,
141
]
} |
three tetracarboxylate porphyrins , apart from coproporphyrin , were isolated from the faeces of patients with symptomatic cutaneous hepatic porphyria and of rats with porphyria caused by hexachlorobenzene poisoning . | NA | {
"id": "C0032712",
"name": "porphyrins",
"pos": [
23,
33
]
} | {
"id": "C0009988",
"name": "coproporphyrin",
"pos": [
47,
61
]
} |
two of the porphyrins were identified as tris- ( 2-carboxyethyl ) -carboxymethyl ethyl trimethyl porphin ( isocoproporphyrin ) and tris- ( 2-carboxyethyl ) -carboxymethyl trimethyl porphin ( de-ethyliso-coproporphyrin ) . | NA | {
"id": "C0032712",
"name": "porphyrins",
"pos": [
11,
21
]
} | {
"id": "C0009988",
"name": "coproporphyrin",
"pos": [
203,
217
]
} |
the third porphyrin , previously reported to be an analogue of coproporphyrin in which one propionate group is replaced by an alpha- or beta-hydroxypropionate group , was shown to be tris- ( 2-carboxyethyl ) -carboxymethyl- ( 1-hydroxyethyl ) -trimethyl porphin ( hydroxyisocoproporphyrin ) . | NA | {
"id": "C0032712",
"name": "porphyrin",
"pos": [
10,
19
]
} | {
"id": "C0009988",
"name": "coproporphyrin",
"pos": [
274,
288
]
} |
studies of the liver glycogen of mice during the growth of a glycogen-free and a glycogen-containing subline of the ehrlich-lettre ascites tumour . | NA | {
"id": "C0023902",
"name": "liver glycogen",
"pos": [
15,
29
]
} | {
"id": "C0017911",
"name": "glycogen",
"pos": [
81,
89
]
} |
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