text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
several features of the scalp hair , such as form , color , thickness , density , maximal length , tensile strength , etc . are clearly genetically determined . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
8,
16
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
90,
96
]
} |
in this review of such diseases we designate changes in the skin and hair as being infectious , toxic or allergic in origin . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
23,
31
]
} | {
"id": "C0009450",
"name": "infectious",
"pos": [
83,
93
]
} |
special attention must be paid to the depressed elderly patient with cardiovascular disease or hypertension . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular disease",
"pos": [
69,
91
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
95,
107
]
} |
if the cancer cells turn over in this way , the tumor must grow slowly , remaining as an intramucosal cancer for a relatively long period . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
48,
53
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
102,
108
]
} |
in 56 % of cases there were bilateral aneurysms and in 24 % of cases there was an associated aortic aneurysm . | nichd_parent_of | {
"id": "C0002940",
"name": "aneurysms",
"pos": [
38,
47
]
} | {
"id": "C0003486",
"name": "aortic aneurysm",
"pos": [
93,
108
]
} |
gradually added to the classical digestive symptoms and signs were those of respiratory disorders varying between asthma and the `` '' missed sudden death '' '' syndrome . | nichd_parent_of | {
"id": "C0035204",
"name": "respiratory disorders",
"pos": [
76,
97
]
} | {
"id": "C0004096",
"name": "asthma",
"pos": [
114,
120
]
} |
striking observations concerning changes manifest during the course of development from initial language acquisition through childhood and adolescence will also add to the information regarding this syndrome 's natural history and prognosis . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
125,
134
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
139,
150
]
} |
thirteen of these 16 children were among the 21 infants who had perinatal risk factors . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
21,
29
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
48,
55
]
} |
disorders included in this classification are : ehlers-danlos syndrome , pseudoxanthoma elasticum , arteriosclerosis obliterans , venous calcifications , crystal deposition disorders , and calcification resulting from neurologic disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
0,
9
]
} | {
"id": "C0027765",
"name": "neurologic",
"pos": [
218,
228
]
} |
because abnormalities in interleukin 2 ( il 2 ) production have been reported in the blood of patients with certain autoimmune diseases , we have examined the lymphocytes from patients with sjogren 's syndrome ( ss ) in which it is possible to obtain simultaneous samples of inflammatory site ( i.e. , salivary gland ) l... | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune diseases",
"pos": [
116,
135
]
} | {
"id": "C1527336",
"name": "sjogren 's syndrome",
"pos": [
190,
209
]
} |
we used sem to study 38 patients ' tumors , representing 16 histological malignancies , growing in soft agar . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
35,
41
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
73,
85
]
} |
results obtained in control patients with thrombocytopenia and increased platelet size ( may-hegglin anomaly and vwd type iib ) excluded a nonspecific increase of glycoprotein ib in the platelets of the patients with pseudo-vwd . | nichd_parent_of | {
"id": "C0042974",
"name": "vwd",
"pos": [
113,
116
]
} | {
"id": "C1280798",
"name": "pseudo-vwd",
"pos": [
217,
227
]
} |
the mean age at which venereal infection was acquired was higher for syphilis than for gonorrhoea , but the mean age at diagnosis of cancer was younger for the syphilis group ; | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
31,
40
]
} | {
"id": "C0039128",
"name": "syphilis",
"pos": [
160,
168
]
} |
a recent rise in the incidence of cancer of the testis in affluent countries and affluent social strata suggests either an iatrogenic effect analogous with adenocarcinoma of the vagina or a prenatal infection analogous with congenital rubella syndrome . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
199,
208
]
} | {
"id": "C0035921",
"name": "congenital",
"pos": [
224,
234
]
} |
bomba 's ( 1984 , journal of experimental child psychology , 37 , 609-636 ) recent report that infants respond to the orientation of a visual stimulus in a categorical-like manner . | nichd_parent_of | {
"id": "C0008059",
"name": "child",
"pos": [
42,
47
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
95,
102
]
} |
four out of seven research workers into swayback disease , a neurological disease of lambs , developed symptoms and signs of multiple sclerosis , and were reported in 1947 . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
49,
56
]
} | {
"id": "C0027765",
"name": "neurological disease",
"pos": [
61,
81
]
} |
this study compares spect images of the two tracers in six subjects : four stroke cases , one transitory ischemic attack case and one normal subject . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
75,
81
]
} | {
"id": "C0007787",
"name": "transitory ischemic attack",
"pos": [
94,
120
]
} |
the severity and course of the disease was evaluated by clinical examination , slit lamp biomicroscopy and histopathologic observations . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
43,
52
]
} | {
"id": "C0031809",
"name": "clinical",
"pos": [
56,
64
]
} |
infectious diarrhea appears to be common in diaper-age children in day care centers , but the patterns of disease differ for different pathogens and for the infant and toddler age groups . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
55,
63
]
} | {
"id": "C0021270",
"name": "infant",
"pos": [
157,
163
]
} |
infectious diarrhea appears to be common in diaper-age children in day care centers , but the patterns of disease differ for different pathogens and for the infant and toddler age groups . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
55,
63
]
} | {
"id": "C0682053",
"name": "toddler age groups",
"pos": [
168,
186
]
} |
measurements of plasma zinc and copper concentration , weight , length , head circumference , and tricipital and subscapular skinfolds were carried out at 10 and 120 days of age . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
64,
70
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
73,
91
]
} |
a defunctionalizing procedure was done as part of the initial operation in 11 of the 42 patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
20,
29
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
62,
71
]
} |
type 1 cysts , two cases whose cysts were infraduodenal and retropancreatic in position , and three cases of choledochal cysts with both proximal and distal atresia of bile ducts . | nichd_parent_of | {
"id": "C0010709",
"name": "cysts",
"pos": [
7,
12
]
} | {
"id": "C0008340",
"name": "choledochal cysts",
"pos": [
109,
126
]
} |
sociodemographic and psychodynamic similarities and differences among four subgroups of eating disordered females seeking outpatient consultations for anorexia nervosa and bulimia are presented . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disordered",
"pos": [
88,
105
]
} | {
"id": "C0003125",
"name": "anorexia nervosa",
"pos": [
151,
167
]
} |
sociodemographic and psychodynamic similarities and differences among four subgroups of eating disordered females seeking outpatient consultations for anorexia nervosa and bulimia are presented . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disordered",
"pos": [
88,
105
]
} | {
"id": "C0006370",
"name": "bulimia",
"pos": [
172,
179
]
} |
supporting the spectrum concept of eating disorders , the four diagnostic subgroups are : anorexia nervosa , restricting ; | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorders",
"pos": [
35,
51
]
} | {
"id": "C0003125",
"name": "anorexia nervosa",
"pos": [
90,
106
]
} |
a family study of eating disorders in first and second-degree relatives of anorexia nervosa and nonanorexic psychiatrically ill control probands found increased rates of anorexia-nervosa , bulimia nervosa , and subclinical anorexia nervosa in relatives of anorexic probands . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorders",
"pos": [
18,
34
]
} | {
"id": "C2267227",
"name": "bulimia nervosa",
"pos": [
189,
204
]
} |
a family study of eating disorders in first and second-degree relatives of anorexia nervosa and nonanorexic psychiatrically ill control probands found increased rates of anorexia-nervosa , bulimia nervosa , and subclinical anorexia nervosa in relatives of anorexic probands . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorders",
"pos": [
18,
34
]
} | {
"id": "C0003125",
"name": "anorexia",
"pos": [
223,
231
]
} |
a series of 27 cases is presented where eating disorders have been followed by clinical alcoholism or where alcoholic patients have shown to have clear previous episodes of anorexia nervosa or bulimia . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorders",
"pos": [
40,
56
]
} | {
"id": "C0003125",
"name": "anorexia nervosa",
"pos": [
173,
189
]
} |
a series of 27 cases is presented where eating disorders have been followed by clinical alcoholism or where alcoholic patients have shown to have clear previous episodes of anorexia nervosa or bulimia . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorders",
"pos": [
40,
56
]
} | {
"id": "C0006370",
"name": "bulimia",
"pos": [
193,
200
]
} |
these results suggest that the secretory immune system in the female mouse reproductive tract may play a role in returning the uterus to an aseptic state after mating by at least three mechanisms : direct blocking of attachment sites involved in bacterial binding to mucosal epithelium , agglutination of bacteria and th... | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
350,
359
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
422,
430
]
} |
further analysis indicated that rheumatoid factor ( rf ) positive [ ra ( + ) ] sera averaged 30.4 % clqba , significantly greater than the 3.9 % clqba in ra rf negative [ ra ( - ) ] sera ( p less than 0.01 ) . | nichd_parent_of | {
"id": "C0003864",
"name": "ra",
"pos": [
68,
70
]
} | {
"id": "C0003873",
"name": "ra",
"pos": [
184,
186
]
} |
the ahi appears to be a useful measure for further studies in ra and a valuable clinical tool in monitoring the psychological status of patients with ra . | nichd_parent_of | {
"id": "C0003864",
"name": "ahi",
"pos": [
4,
7
]
} | {
"id": "C0003873",
"name": "ra",
"pos": [
150,
152
]
} |
each group was further divided into two subgroups depending on the presence ( arrhythmia group ) or the absence ( non-arrhythmia group ) of ventricular arrhythmias . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
78,
88
]
} | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
140,
163
]
} |
cmnx was administered against gyneco-obstetrical infections such as intrauterine , intrapelvic , adnexal infections and postoperative wound infections with daily dose of 2 g and was effective in 11 cases out of 12 cases ( 91.7 % ) , and 81.8 % of bacteriological effect was obtained . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
49,
59
]
} | {
"id": "C0038941",
"name": "postoperative wound infections",
"pos": [
120,
150
]
} |
in special cases of uveitis ( behcet 's syndrome , sympathetic ophthalmia , anterior uveitis in children with jra ) cytostatic treatment seems justified . | nichd_parent_of | {
"id": "C0042164",
"name": "uveitis",
"pos": [
20,
27
]
} | {
"id": "C0042165",
"name": "anterior",
"pos": [
76,
84
]
} |
six hundred and seventy-three children ( 483 newborns and 190 older selected children ) were screened for tetrahydrobiopterin ( bh4 ) deficiency by hplc of urine pterins and bh4 load test . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
30,
38
]
} | {
"id": "C0021289",
"name": "newborns",
"pos": [
45,
53
]
} |
three different inherited disorders are known in which thiamine may exert a beneficial effect : maple syrup urine disease ( msud ) , lactic acidaemia and the syndrome of megaloblastic anaemia with sensorineural deafness and diabetes mellitus . | nichd_parent_of | {
"id": "C0019247",
"name": "inherited disorders",
"pos": [
16,
35
]
} | {
"id": "C0024776",
"name": "maple syrup urine disease",
"pos": [
96,
121
]
} |
associated abnormalities included ebstein 's anomaly ( 12 % ) , other arrhythmias ( 34 % ) , coronary artery disease ( 6 % ) , cardiomyopathy ( 6 % ) , and congenital heart disease other than ebstein 's anomaly ( 22 % ) . | nichd_parent_of | {
"id": "C0152021",
"name": "congenital heart disease",
"pos": [
156,
180
]
} | {
"id": "C0013481",
"name": "ebstein 's anomaly",
"pos": [
192,
210
]
} |
we previously proposed that abnormalities of bile acid metabolism play a pathogenetic role in myd , in which deoxycholic acid acts as a maternal factor in association with the onset of congenital myd . | nichd_parent_of | {
"id": "C0027126",
"name": "myd",
"pos": [
94,
97
]
} | {
"id": "C0410226",
"name": "congenital myd",
"pos": [
185,
199
]
} |
the immunological status of the patient was not examined , but her 10 year history of multiple mycotic abscesses and dermatophytoses suggested some abnormalities . | nichd_parent_of | {
"id": "C0026946",
"name": "mycotic",
"pos": [
95,
102
]
} | {
"id": "C0011636",
"name": "dermatophytoses",
"pos": [
117,
132
]
} |
it has been found that this characteristic is determined only by the gels ' heating temperatures . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
28,
42
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
84,
96
]
} |
similarly , with the cooperation of local universities , hospitals , and physicians , tumor and tissue registries necessary for the study of cancer incidence have been developed . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
86,
91
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
141,
147
]
} |
although the choice of therapy for this tumor remain controversial , the preferred treatment has been radiotherapy , in conjunction with surgical procedures for the mass of middle cranial fossa . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
40,
45
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
165,
169
]
} |
the results suggest that the absence of fetal breathing movements differentiates true labor from false labor . | nichd_parent_of | {
"id": "C0022864",
"name": "labor",
"pos": [
86,
91
]
} | {
"id": "C0085598",
"name": "labor",
"pos": [
103,
108
]
} |
characteristic clinical signs of the fatal mycotoxicosis caused by d. campanulata culture material in goats and sheep were anorexia , apathy , diarrhoea and ruminal stasis . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
15,
29
]
} | {
"id": "C0003123",
"name": "anorexia",
"pos": [
123,
131
]
} |
finally we describe the need to change the thinking about 'pain ' from the pathological or disease model , appropriate to acute pain , to a learning model when discussing the excess disability and suffering of chronic pain patients . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
59,
63
]
} | {
"id": "C0150055",
"name": "chronic",
"pos": [
210,
217
]
} |
this finding is specific for cerebrohepatorenal syndrome fibroblasts since cell lines of patients with childhood adrenoleukodystrophy and neuronal ceroidlipofuscinosis utilized the lipid precursors of plasmalogen biosynthesis at normal rates . | nichd_parent_of | {
"id": "C0043459",
"name": "cerebrohepatorenal syndrome",
"pos": [
29,
56
]
} | {
"id": "C0162309",
"name": "adrenoleukodystrophy",
"pos": [
113,
133
]
} |
the finding of normal microsomal biosynthetic steps was exploited to devise a novel diagnostic assay in fibroblasts and amniocytes based on the comparison of [ 3h/14c ] isotope ratios within aldehydes released from plasmalogens by acid hydrolysis . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
4,
11
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
84,
94
]
} |
benzathine penicillin g has withstood the test of time as the ideal drug to treat early , infectious syphilis and to prevent and treat group a streptococcal infections . | nichd_parent_of | {
"id": "C0009450",
"name": "infectious",
"pos": [
90,
100
]
} | {
"id": "C0039128",
"name": "syphilis",
"pos": [
101,
109
]
} |
as determined by a procedure that evaluates triply aligned sequences , the probability that the similarities among the segments described here arose by chance was no greater than 0.001 . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
19,
28
]
} | {
"id": "C0220825",
"name": "evaluates",
"pos": [
34,
43
]
} |
in recent years several lines of evidence have emerged suggesting that eating disorders in general , and bulimia in particular , are in some way linked to affective illness . | nichd_parent_of | {
"id": "C0013473",
"name": "eating",
"pos": [
71,
77
]
} | {
"id": "C0006370",
"name": "bulimia",
"pos": [
105,
112
]
} |
we also propose that the initial interaction of an organism such as a parasite and the mammalian host involves early recognition by the macrophage , thereby initiating both the humoral and cellular acute phase reactions and subsequently affects the immune response against the parasite . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
51,
59
]
} | {
"id": "C0030498",
"name": "parasite",
"pos": [
277,
285
]
} |
variations in the acute phase reaction may help to explain differences in susceptibility to infectious organisms and the presence or lack of host killing mechanisms for the parasite . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
103,
112
]
} | {
"id": "C0030498",
"name": "parasite",
"pos": [
173,
181
]
} |
the clinical picture is not very typical , except for circumscript vertebral pathology , and frequently the disease process lacks the humoral signs of inflammation and infection . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
108,
115
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
168,
177
]
} |
she displayed all major findings of this disease , e.g . oral and genital ulcers , chorioretinitis , dermatologic lesions and arthritis , as well as a severe neurological syndrome consisting of conjugated paralysis of the vertical gaze ( parinaud 's syndrome ) and disorientation . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
41,
48
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
250,
258
]
} |
the results of the diarrhoea surveillance showed that there was considerable variation between individual children . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
95,
105
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
106,
114
]
} |
the question of the cbs status of brain-fag demonstrates the need to clearly differentiate such disease features as symptom clusters , labels for those clusters , and notions of etiology . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
96,
103
]
} | {
"id": "C0039082",
"name": "symptom",
"pos": [
116,
123
]
} |
this organism and other nondiphtheria corynebacteria must be considered as potentially serious pathogens in man . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
5,
13
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
95,
104
]
} |
groups of acute and subchronic pain and groups of subchronic and chronic pain differed only in several parameters , suggesting an intermittent phase in acute pain transition into chronicity . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
31,
35
]
} | {
"id": "C0150055",
"name": "chronic pain",
"pos": [
65,
77
]
} |
interestingly , serum lactate levels markedly increase when both peep and iap are applied , a finding not explained by the fall in co . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
94,
101
]
} | {
"id": "C0085639",
"name": "fall",
"pos": [
123,
127
]
} |
with the use of a two-dimensional range-gated pulsed-doppler ultrasound system , doppler examinations of the aorta and cerebral arteries were performed in 20 normal newborn infants and in 54 infants with various forms of congenital heart disease ( i.e . patent ductus arteriosus , coarctation of the aorta , critical aor... | nichd_parent_of | {
"id": "C0152021",
"name": "of congenital heart",
"pos": [
218,
237
]
} | {
"id": "C0013274",
"name": "patent ductus arteriosus",
"pos": [
254,
278
]
} |
with the use of a two-dimensional range-gated pulsed-doppler ultrasound system , doppler examinations of the aorta and cerebral arteries were performed in 20 normal newborn infants and in 54 infants with various forms of congenital heart disease ( i.e . patent ductus arteriosus , coarctation of the aorta , critical aor... | nichd_parent_of | {
"id": "C0152021",
"name": "of congenital heart",
"pos": [
218,
237
]
} | {
"id": "C0242855",
"name": "pulmonary atresia",
"pos": [
335,
352
]
} |
the indications for operation were flexion-fractures , second- or third-grade compound fractures , vessel or nerve lesions and for easier nursing of polytraumatized patients . | nichd_parent_of | {
"id": "C0016658",
"name": "fractures",
"pos": [
43,
52
]
} | {
"id": "C0016662",
"name": "compound fractures",
"pos": [
78,
96
]
} |
positive cytologic findings are conclusive for stage d disease , while negative cytology may be accepted as definitive only when the neoplasm is well differentiated or the gleason sum is 2-3-4 . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
55,
62
]
} | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
133,
141
]
} |
a common feature for liposomes from gp of all the three viruses consisted in the formation of two morphological variants of structural complexes : filaments of various lengths and composition in them of gp and vesicles , the arrays of gp in which were similar or identical to those of viral membrane . | nichd_parent_of | {
"id": "C1521970",
"name": "feature",
"pos": [
9,
16
]
} | {
"id": "C1444754",
"name": "lengths",
"pos": [
168,
175
]
} |
the sustained high incidence of staphylococcal toxic shock syndrome ( tss ) in utah provided an opportunity to examine changes in the epidemiology of this disease during a period of greater media attention to the syndrome and increased scientific understanding of its etiology and pathogenesis . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
155,
162
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
213,
221
]
} |
apoplexy is the clinical term for sudden loss of consciousness , followed by paralysis resulting from a cerebral haemorrhage , occlusion of a cerebral artery , thrombosis , or embolism , with loss of cerebral function of the affected brain region . | nichd_parent_of | {
"id": "C0038454",
"name": "apoplexy",
"pos": [
0,
8
]
} | {
"id": "C2937358",
"name": "cerebral haemorrhage",
"pos": [
104,
124
]
} |
inflammatory changes of the hip joint in rheumatoid arthritis often lead to secundary protrusio acetabuli . | nichd_parent_of | {
"id": "C0003864",
"name": "inflammatory changes",
"pos": [
0,
20
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
41,
61
]
} |
in the course of bronchoalveolar lavages performed in 115 immunocompromised patients in order to investigate the occurrences of pneumonitis , pneumocystis carinii pneumonia was diagnosed by demonstration of cysts in bronchoalveolar lavage specimens from 11 patients . | nichd_parent_of | {
"id": "C0032285",
"name": "pneumonitis",
"pos": [
128,
139
]
} | {
"id": "C1535939",
"name": "pneumocystis",
"pos": [
142,
154
]
} |
the purpose of this study was to examine the extent of the disease , the degree of mast cell infiltration in skin and bone marrow , to evaluate the most frequently used diagnostic methods , to study some immunological functions and genetic markers , to determine the histamine metabolism and to test a new drug which inh... | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic methods",
"pos": [
169,
187
]
} | {
"id": "C0022885",
"name": "test",
"pos": [
295,
299
]
} |
the immunomodulating capabilities of the agents tested are assessed by their effects on the allergic contact reaction to oxazolone , a cell-mediated delayed hypersensitivity reaction . | nichd_parent_of | {
"id": "C0020517",
"name": "allergic",
"pos": [
92,
100
]
} | {
"id": "C0020522",
"name": "delayed",
"pos": [
149,
156
]
} |
this procedure allows a description of renal cortical morphology , split function determination and run-off evaluation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
108,
118
]
} |
this finding supports the idea of the heterogeneity of schizophrenia , and raises the possibility of developing biochemical methods to delineate the diagnostic category of schizophrenia . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
5,
12
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
149,
159
]
} |
the methodology in psychiatric genetics , including family studies , twin studies , and adoption strategies , developed during the last 70 years to a high degree of perfection , has established beyond doubt the heritability of the major psychoses , the schizophrenic and manic-depressive disorders . | nichd_parent_of | {
"id": "C0004936",
"name": "psychoses",
"pos": [
237,
246
]
} | {
"id": "C0005586",
"name": "manic-depressive disorders",
"pos": [
271,
297
]
} |
metrizamide ct myelography , highly recommended in infants and children , may be omitted in the neonate with no neurologic deficit . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
63,
71
]
} | {
"id": "C0021289",
"name": "neonate",
"pos": [
96,
103
]
} |
twelve patients had ventricular tachycardia ( vt ) as their initial arrest arrhythmia and 1 patient had bradycardia followed by ventricular fibrillation ( vf ) . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
75,
85
]
} | {
"id": "C0428977",
"name": "bradycardia",
"pos": [
104,
115
]
} |
the clinical signs and symptoms of anemia , weight loss , abdominal pain , vomiting , and intermittent intestinal obstruction can be found . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
4,
18
]
} | {
"id": "C0042963",
"name": "vomiting",
"pos": [
75,
83
]
} |
of these patients , 44 % had a p isoamylase fraction less than 0.75 of the total amylase value , a finding apparently incompatible with a diagnosis of acute pancreatitis as identified by our control group . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
99,
106
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
138,
147
]
} |
in this study , clinical findings of consecutive hospitalized patients were compared : nine with toxic shock syndrome ( confirmed by a modification of the collaborative strict case definition ) and 120 with potentially similar diagnoses ( bacteremia with shock , meningococcemia , staphylococcus aureus bacteremia , scar... | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
16,
33
]
} | {
"id": "C0011900",
"name": "diagnoses",
"pos": [
227,
236
]
} |
the question of the effect of pregnancy on renal disease in women with moderate renal insufficiency at the start of pregnancy is unanswerable on the basis of available data . | nichd_parent_of | {
"id": "C0022658",
"name": "renal disease",
"pos": [
43,
56
]
} | {
"id": "C0035078",
"name": "renal insufficiency",
"pos": [
80,
99
]
} |
glyburide and other sulfonylureas consistently enhance receptor binding in cells from patients with non-insulin-dependent diabetes mellitus , whereas no effects and mixed effects have been demonstrated in cells from patients with insulin-dependent diabetes mellitus and in normal cells , respectively . | nichd_parent_of | {
"id": "C0011849",
"name": "non-insulin-dependent diabetes mellitus",
"pos": [
100,
139
]
} | {
"id": "C0011854",
"name": "insulin-dependent diabetes mellitus",
"pos": [
230,
265
]
} |
thrombotic microangiopathy in a renal allograft may either reflect a recurrence of the patient 's original disease , i.e. , thrombotic thrombocytopenic purpura , hemolytic-uremic syndrome , or more commonly may be a manifestation of allograft rejection . | nichd_parent_of | {
"id": "C2717961",
"name": "thrombotic microangiopathy",
"pos": [
0,
26
]
} | {
"id": "C0034155",
"name": "thrombotic thrombocytopenic purpura",
"pos": [
124,
159
]
} |
the cause of this syndrome is unknown , but affected patients appear to have a high incidence of positive radioallergosorbent tests to a conjugate of human serum albumin and ethylene oxide , suggesting that ethylene oxide , a substance used to dry sterilize artificial kidneys , may be an offending allergen . | nichd_parent_of | {
"id": "C0439861",
"name": "substance",
"pos": [
226,
235
]
} | {
"id": "C0002092",
"name": "allergen",
"pos": [
299,
307
]
} |
all cases ( n = 190 ) that were pathologically diagnosed from 1975 to 1982 as hydatidiform mole , invasive mole , or choriocarcinoma were ascertained . | nichd_parent_of | {
"id": "C0020217",
"name": "hydatidiform mole",
"pos": [
78,
95
]
} | {
"id": "C0008493",
"name": "invasive mole",
"pos": [
98,
111
]
} |
twenty-two mathematical formulas purporting to quantitate fetal heart rate variability , 13 for short-term and nine for long-term variability , were examined by using artificially generated numbers representing either short-term variability or long-term variability . | nichd_parent_of | {
"id": "C0429478",
"name": "fetal heart rate",
"pos": [
58,
74
]
} | {
"id": "C2985325",
"name": "short-term",
"pos": [
218,
228
]
} |
isotretinoin is contraindicated in pregnancy because of the many reported congenital abnormalities after maternal use ( including microphthalmos , orbital hypertelorism , and optic nerve hypoplasia ) . | nichd_parent_of | {
"id": "C0000768",
"name": "congenital abnormalities",
"pos": [
74,
98
]
} | {
"id": "C0026010",
"name": "microphthalmos",
"pos": [
130,
144
]
} |
although several health habits and behaviors are commonly cited in medical and nursing textbooks as potential causes of urinary tract infection ( uti ) in women , few have been studied in a systematic fashion . | nichd_parent_of | {
"id": "C0004927",
"name": "behaviors",
"pos": [
35,
44
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
79,
86
]
} |
seventy-three tumors were squamous cell carcinomas , and the remaining 5 were cancers that originated in the salivary gland . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
14,
20
]
} | {
"id": "C0006826",
"name": "cancers",
"pos": [
78,
85
]
} |
apart from the alternative use of etomidate and methohexitone the anaesthetic procedure did not differ : after a small dose of alfentanil anaesthesia was induced by a bolus dose of the hypnotic followed by a continuous infusion of the drug . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
78,
87
]
} | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
138,
149
]
} |
[ differential diagnosis and treatment of disorders of kidney excretory function and acute kidney failure in the post-resuscitation period in patients with massive blood loss and trauma ] . | nichd_parent_of | {
"id": "C0022658",
"name": "of disorders",
"pos": [
39,
51
]
} | {
"id": "C0022660",
"name": "acute kidney failure",
"pos": [
85,
105
]
} |
because abnormal pulmonary elastolysis may be largely completed before symptoms of emphysema develop in aat-deficient persons , we also tested 6 asymptomatic adults with homozygous aat deficiency ( pizz ) and 5 pizz children . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
118,
125
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
216,
224
]
} |
these abnormalities are mainly asymmetrical body development ( hypotrophy of the leg in two cases , hemihypertrophy of body in five ) , hemihypertrophy of brain with psychomotor retardation in three patients , nevus flameus on lumbar region in one and syndactylies on hands and feet in one . | nichd_parent_of | {
"id": "C0000768",
"name": "abnormalities",
"pos": [
6,
19
]
} | {
"id": "C0332890",
"name": "hemihypertrophy",
"pos": [
136,
151
]
} |
three approaches used to treat this immunodeficiency have included wholescale immune replacement through lymphocyte transfers , bone marrow transplantation , and thymic implantation ; | nichd_parent_of | {
"id": "C0087111",
"name": "treat",
"pos": [
25,
30
]
} | {
"id": "C0005961",
"name": "bone marrow transplantation",
"pos": [
128,
155
]
} |
protrusio acetabuli , uncommon in osteo-arthritis is the commonest presentation in rheumatoid arthritis because of the concentric cartilage degradation which erodes the acetabulum medially and proximally . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
40,
49
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
83,
103
]
} |
seven patients with a rare syndrome of diabetes insipidus ( di ) , diabetes mellitus ( dm ) , optic atrophy ( oa ) , neurosensory deafness ( d ) , atony of the urinary tract , and other abnormalities ( wolfram or didmoad syndrome ) are reported . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
"pos": [
27,
35
]
} | {
"id": "C0043207",
"name": "didmoad syndrome",
"pos": [
213,
229
]
} |
we describe two children who have this disease and had clumps of blast cells in their bone marrow , a finding usually attributed to metastatic tumor . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
39,
46
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
143,
148
]
} |
fifty-one patients ( 49 % ) developed major complications of the operative field involving the gastrointestinal tract ( fistula or obstruction ) , the urinary tract ( fistula , infection , or obstruction ) , or the wound ( abscess , dehiscence/necrosis , or hemorrhage ) . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
177,
186
]
} | {
"id": "C0000833",
"name": "abscess",
"pos": [
223,
230
]
} |
in an attempt to find a rapid and simple procedure for radioimmunoassay of apolipoprotein a-1 without using organic solvents , the serum was subjected to various physical and chemical treatments which disrupt or alter high density lipoproteins ( hdl ) . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
41,
50
]
} | {
"id": "C0087111",
"name": "treatments",
"pos": [
184,
194
]
} |
in a study of the retinopathy profile of 40 patients with tropical pancreatic diabetes , a form of secondary diabetes seen in tropical countries , diabetic retinopathy was detected in 13 patients . | nichd_parent_of | {
"id": "C0035309",
"name": "retinopathy",
"pos": [
18,
29
]
} | {
"id": "C0011884",
"name": "diabetic",
"pos": [
147,
155
]
} |
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