text stringlengths 57 1.72k | relation stringclasses 125
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|---|---|---|---|
stool specimens from a total of 7517 persons were examined , including specimens from 4915 children age 7-14 years in 29 localities , as well as from the total population of four of the more heavily infected localities . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
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} | {
"id": "C0008059",
"name": "children",
"pos": [
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} |
a significant correlation was noted between the presence of aneuploid stem lines and high stage disease ( p equals 0.004 ) but there was no significant correlation between ploidy status and tumor grade . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
96,
103
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
190,
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]
} |
although there was a significant difference ( p equals 0.037 ) in the incidence of disease progression in patients with diploid tumors ( 13 % ) versus those with aneuploid tumors ( 35 % ) in the total population , and kaplan-meier disease-specific survival curves demonstrated a survival advantage for patients with dipl... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
83,
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]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
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} |
between january 1987 and december 1988 the procedure was performed on 32 patients , 31 of whom submitted sperm and were available to evaluate . | nichd_parent_of | {
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"name": "procedure",
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} | {
"id": "C0220825",
"name": "evaluate",
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} |
our results indicate the potential importance of urban populations of this mammal as reservoirs for at least one important zoonotic disease , rmsf , in western texas . | nichd_parent_of | {
"id": "C0043528",
"name": "zoonotic disease",
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} | {
"id": "C0035793",
"name": "rmsf",
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} |
ct scans revealed bilateral acquired cystic disease of the kidney ( acdk ) and a mass ( phi 4 cm ) in the medial portion of the left kidney , which was angiographically a hypovascular tumor . | nichd_parent_of | {
"id": "C0012634",
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} | {
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} |
all procedures were done on an outpatient basis without anaesthesia , except for local anaesthesia for skin biopsy . | nichd_parent_of | {
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} | {
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} |
all procedures were done on an outpatient basis without anaesthesia , except for local anaesthesia for skin biopsy . | nichd_parent_of | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
56,
67
]
} | {
"id": "C0002921",
"name": "local anaesthesia",
"pos": [
81,
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]
} |
because measles causes an estimated 2 million deaths per year among children in developing countries , including a substantial proportion of infants less than nine months old -- the age at which vaccination is recommended -- there has been interest in using different strains of vaccine and higher doses to achieve immun... | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
68,
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} | {
"id": "C0021270",
"name": "infants",
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cytogenetic analysis has identified chromosome 11p13 as the smallest overlap region for deletions found in individuals with wagr syndrome , which includes wilms tumour ( a recessive childhood nephroblastoma ) , aniridia , genito-urinary abnormalities and mental retardation . | nichd_parent_of | {
"id": "C0027708",
"name": "wilms tumour",
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} | {
"id": "C1333015",
"name": "childhood nephroblastoma",
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206
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} |
this case illustrates the ineffectiveness of parenteral albumin infusions for treatment of enteral edema and demonstrates the restoration of normal intestinal absorptive capacity when ultrafiltration was instituted and the patient 's generalized edematous state was corrected . | nichd_parent_of | {
"id": "C0013604",
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} | {
"id": "C0151603",
"name": "generalized edematous",
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234,
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} |
median plasma vitamin k1 levels were comparable in mothers receiving the drug by the im route only and by both the im and oral routes ( 10.533 versus 11.928 ng/ml ; p = .460 ) . | nichd_parent_of | {
"id": "C0013153",
"name": "drug",
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} | {
"id": "C1527415",
"name": "oral routes",
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} |
this review evaluates a number of historic and physical factors and laboratory tests that may aid in the prediction of preeclampsia . | nichd_parent_of | {
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"name": "evaluates",
"pos": [
12,
21
]
} | {
"id": "C0031809",
"name": "physical",
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} |
although the overall incidence of ectopic gestation has been rising over the past 30 years , unilateral twin tubal gestation is still a relatively rare event . | nichd_parent_of | {
"id": "C0032987",
"name": "ectopic gestation",
"pos": [
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51
]
} | {
"id": "C0032994",
"name": "tubal gestation",
"pos": [
109,
124
]
} |
a review of three cases in which these disease processes coexisted demonstrates that endometriosis can easily be mistaken for tumor extension on pelvic examination , computed tomography , and even gross inspection at laparotomy , resulting in incorrect staging and inappropriate management decisions . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
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]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
126,
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]
} |
acarboxyprothrombin could be demonstrated in about 14 % at the both age of life of breast-fed children , but not in the groups of bottle-fed infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
94,
102
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
141,
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]
} |
the authors describe the history of a nine year old girl , with a disease that seemed to be hyperprostaglandin-e syndrome . | nichd_parent_of | {
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"name": "disease",
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]
} | {
"id": "C0039082",
"name": "syndrome",
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121
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} |
to assess the effects of intervention in cerebral palsy , 48 infants 12 to 19 months of age , with mild to severe spastic diplegia , were randomly assigned to receive either 6 months of infant stimulation followed by 6 months of physical therapy ( test group ) or 12 months of neurodevelopmental physical therapy ( contr... | nichd_parent_of | {
"id": "C0007789",
"name": "cerebral palsy",
"pos": [
41,
55
]
} | {
"id": "C0023882",
"name": "spastic diplegia",
"pos": [
114,
130
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} |
once the diagnosis is ensured , therapy should include appropriate rest , physical and occupational therapy , involvement of the family or a supportive caregiver , and , most important , participation of the patient . | nichd_parent_of | {
"id": "C0087111",
"name": "therapy",
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39
]
} | {
"id": "C1318464",
"name": "occupational",
"pos": [
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} |
propionic acidemia is an inherited disorder of organic acid metabolism that is caused by deficiency of propionyl-coa carboxylase ( pcc ; ec 6.4.1.3 ) . | nichd_parent_of | {
"id": "C1263739",
"name": "disorder of organic acid metabolism",
"pos": [
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]
} | {
"id": "C0268579",
"name": "deficiency of propionyl-coa carboxylase",
"pos": [
89,
128
]
} |
the presumed obstructing tumor was seen as a hypoechoic nodule near the hilum or as a well-defined hyperechoic mass inside the partially consolidated lung . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
25,
30
]
} | {
"id": "C0577559",
"name": "mass",
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]
} |
a number of humoral and cellular immune abnormalities are present in patients with early scleroderma ( systemic sclerosis ) . | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
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89,
100
]
} | {
"id": "C0036421",
"name": "systemic sclerosis",
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121
]
} |
two experiments were conducted to evaluate interhemispheric differences in late auditory evoked potentials ( aeps ) during rapid-eye-movement ( rem ) , stage 2 , and stage 4 sleep . | nichd_parent_of | {
"id": "C0004927",
"name": "conducted",
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} | {
"id": "C0037313",
"name": "sleep",
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} |
other organisms that may cause a fraction of the episodes of travelers ' diarrhea include plesiomonas shigelloides , enteroadherent e. coli , adenovirus or other viruses , and cryptosporidium . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
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} | {
"id": "C0042776",
"name": "viruses",
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162,
169
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} |
subsequent work has shown this organism to be what many consider the most important bacterial pathogen of the gut in developed countries in terms of severity of disease and prevalence . | nichd_parent_of | {
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} | {
"id": "C0450254",
"name": "pathogen",
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} |
patients were studied before and at 6 months ( blood and small-intestinal function tests ) and at 24 months ( blood tests ) postoperatively . | nichd_parent_of | {
"id": "C0022885",
"name": "tests",
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} | {
"id": "C0018941",
"name": "blood tests",
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121
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} |
the finding that locally advanced disease ( lad ) and technically unresectable disease could be rendered resectable by preoperative chemotherapy ( eap ) was important . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
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11
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} | {
"id": "C1519810",
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} |
the operative mortality rate ranges from 8.1 in patients undergoing our procedure within 48 hours from the onset of the disease to 28.4 per cent when the operation was delayed for more than 96 hours . | nichd_parent_of | {
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} | {
"id": "C0543467",
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} |
of the stroke types , subarachnoid hemorrhage was not related to any of these indicators , and intracerebral hemorrhage was related only to measured high blood pressure . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
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13
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} | {
"id": "C2937358",
"name": "intracerebral hemorrhage",
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119
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} |
the cost of therapies like bone marrow transplantation has been an important consideration for several decades . | nichd_parent_of | {
"id": "C0087111",
"name": "therapies",
"pos": [
12,
21
]
} | {
"id": "C0005961",
"name": "bone marrow transplantation",
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]
} |
no serious renal failure , renal disease , or tumors in the contralateral kidney occurred among the total group of 52 patients . | nichd_parent_of | {
"id": "C0022658",
"name": "renal",
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11,
16
]
} | {
"id": "C0022665",
"name": "tumors",
"pos": [
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} |
an increase in blood serum-alpha 1-pi level was shown to be associated with tumor advancement but could not be regarded as a marker of cancer . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
76,
81
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
135,
141
]
} |
disease was misdiagnosed in 15.5 % of cases of gastric pathology : cancer was not detected in 12.7 % whereas tumor was erroneously diagnosed in 18.5 % of patients with complicated gastric ulcer and other non-tumor pathology . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
0,
7
]
} | {
"id": "C0027651",
"name": "tumor",
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213
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} |
whatever the choice of the procedure , the surgical treatment of chronic pancreatitis remains palliative and does not alter the natural course of the disease . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
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27,
36
]
} | {
"id": "C0543467",
"name": "surgical treatment",
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61
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} |
some of the newer operations , e.g. , the beger and frey procedures , may make the necessity of a separate operation for biliary decompression superfluous . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
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67
]
} | {
"id": "C0543467",
"name": "operation",
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116
]
} |
in selected patients , it appears to be a good procedure and , possibly , the operation of choice when the disease is predominantly present in the head of the pancreas and/or the uncinate process , especially when strictures involve the common bile duct and duodenum . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
47,
56
]
} | {
"id": "C0543467",
"name": "operation",
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} |
lack of a reference person , a negative attitude on the part of parents toward the child , etc. , frustration within and outside the family have an effect on the manifestation of neuroses and on the course of their development . | nichd_parent_of | {
"id": "C0027361",
"name": "person",
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20,
26
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
83,
88
]
} |
the extent of pulmonary complications following anaesthesia and surgery was significantly correlated to patients aged greater than or equal to 70 years , preoperative chronic obstructive lung disease ( cold ) , major surgery , and to general anaesthesia involving muscle relaxants . | nichd_parent_of | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
48,
59
]
} | {
"id": "C0002915",
"name": "general anaesthesia",
"pos": [
234,
253
]
} |
patients with these new drug-associated spontaneous ventricular arrhythmias often manifested a preexisting substrate for such arrhythmias : sustained vt or vf was induced in 65 % of patients at baseline , and in 58 % of patients when tested with their previously taken antiarrhythmic drug . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
52,
75
]
} | {
"id": "C0042510",
"name": "vf",
"pos": [
156,
158
]
} |
this study evaluated the potential relation between the 2 types of arrhythmias and the effect of conventional modes and rates of pacing for bradycardia on the frequency of the associated tachyarrhythmias . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
67,
78
]
} | {
"id": "C0428977",
"name": "bradycardia",
"pos": [
140,
151
]
} |
this study evaluated the potential relation between the 2 types of arrhythmias and the effect of conventional modes and rates of pacing for bradycardia on the frequency of the associated tachyarrhythmias . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
67,
78
]
} | {
"id": "C0080203",
"name": "tachyarrhythmias",
"pos": [
187,
203
]
} |
the cardiac arrhythmia suppression trial ( cast ) is a randomized , placebo-controlled , double-blind , multicenter clinical trial involving 27 centers and more than 100 hospitals in north america and europe to test the 1-tailed hypothesis that suppression of ventricular arrhythmias in patients with left ventricular dy... | nichd_parent_of | {
"id": "C0003811",
"name": "cardiac arrhythmia",
"pos": [
4,
22
]
} | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
260,
283
]
} |
to evaluate the effect of intensity of physical activity on body fatness and fat distribution , observations of 1366 women and 1257 men who participated in the 1981 canada fitness survey were analyzed . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
3,
11
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
39,
47
]
} |
cytochemically , the tumors were divided into euploid and aneuploid types indicating low and high malignancy potential , respectively . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
21,
27
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
98,
108
]
} |
this function is a quantitative statement of a fundamentally important principle : just as blood pressure is a continuous variable that can range from low to high levels , arterionephrosclerosis is also a continuous variable that can take any degree of abnormality of arterial structure from minimal to maximal . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
19,
31
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
140,
145
]
} |
twenty-five persons were infected , including children , parents , and staff associated with two day care centers . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
12,
19
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
46,
54
]
} |
opportunities to perform procedures did not correlate with the length of time spent on surgical rotations . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
25,
35
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
87,
95
]
} |
the observations were made out of 143 hearts of subjects of different ages , and it was found that the most frequent display of the coronary sinus valve was a semilunar form ( 52 adults , 15 youngsters , 2 children , 3 newborn ) ; | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
206,
214
]
} | {
"id": "C0021289",
"name": "newborn",
"pos": [
219,
226
]
} |
in normal fetuses it was fairly constant throughout pregnancy , but of those with congenital heart disease it was raised in cases of ebstein 's anomaly , tricuspid dysplasia , atrioventricular septal defect , and complete heart block . | nichd_parent_of | {
"id": "C0152021",
"name": "of",
"pos": [
68,
70
]
} | {
"id": "C0013481",
"name": "ebstein 's anomaly",
"pos": [
133,
151
]
} |
birthweight ratio was also strongly and linearly related to body weight , length , and head circumference at 18 months ' corrected age . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
74,
80
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
87,
105
]
} |
patients with defects in the immune system caused by infection with human immunodeficiency virus are predisposed to a variety of opportunistic infections , many of which can be diagnosed by conventional or special microbiological procedures . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
53,
62
]
} | {
"id": "C0029118",
"name": "opportunistic infections",
"pos": [
129,
153
]
} |
similarly , therapeutic trials to treat this disease by apheresis of virus-bearing cells has been ineffective and has , therefore , been abandoned . | nichd_parent_of | {
"id": "C0087111",
"name": "treat",
"pos": [
34,
39
]
} | {
"id": "C0005791",
"name": "apheresis",
"pos": [
56,
65
]
} |
these metabolic abnormalities may be a direct measure of tumor metabolism , or represent alterations in the size or activity of the body cell mass , or both . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
57,
62
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
142,
146
]
} |
the occurrence of falls and the manifestations of three dimensions of agitation ( aggressive behaviors , physically nonaggressive behaviors , verbal behaviors ) were recorded in 408 nursing home residents during each of the three nursing shifts . | nichd_parent_of | {
"id": "C0004927",
"name": "behaviors",
"pos": [
93,
102
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
230,
237
]
} |
the results suggest that mild biochemical hypothyroidism may be found in proteinuric pre-eclampsia , and the concentrations of tt4 , tt3 , ft3 and tsh may reflect the severity of pre-eclampsia . | nichd_parent_of | {
"id": "C0032914",
"name": "pre-eclampsia",
"pos": [
85,
98
]
} | {
"id": "C0341950",
"name": "severity",
"pos": [
167,
175
]
} |
thus the association between chb and both anti-ro ( ss-a ) and anti-la ( ss-b ) antibodies has been demonstrated in an australian population and indicates that anti-la ( ss-b ) , as well as anti-ro ( ss-a ) antibodies may be a risk factor for the development of chb . | nichd_parent_of | {
"id": "C0003241",
"name": "antibodies",
"pos": [
80,
90
]
} | {
"id": "C0075128",
"name": "ss-a",
"pos": [
200,
204
]
} |
careful research using modern techniques , however , has shown that there is no such organism and that livingston-wheeler has apparently mistaken several different types of bacteria , both rare and common , for a unique microbe . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
85,
93
]
} | {
"id": "C0445623",
"name": "microbe",
"pos": [
220,
227
]
} |
doses from 0.02 to 1.0 microgram/kg caused transient clinical signs of porcine systemic toxicosis with reduced appetite , generalized weakness , depression , lethargy , weight loss , and in some instances , death . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
53,
67
]
} | {
"id": "C3714552",
"name": "generalized weakness",
"pos": [
122,
142
]
} |
doses from 0.02 to 1.0 microgram/kg caused transient clinical signs of porcine systemic toxicosis with reduced appetite , generalized weakness , depression , lethargy , weight loss , and in some instances , death . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
53,
67
]
} | {
"id": "C0023380",
"name": "lethargy",
"pos": [
158,
166
]
} |
doses from 0.02 to 1.0 microgram/kg caused transient clinical signs of porcine systemic toxicosis with reduced appetite , generalized weakness , depression , lethargy , weight loss , and in some instances , death . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
53,
67
]
} | {
"id": "C0011065",
"name": "death",
"pos": [
207,
212
]
} |
whereas equidae and small ruminant animals develop diseases related to infection in macrophage populations , felines , macaques and humans develop diseases related to both infection in their macrophages and elimination of their t lymphocytes . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
51,
59
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
172,
181
]
} |
in a panel of 12 human cancer cell lines [ melanoma ( 4 ) , ovary ( 2 ) , head and neck ( 3 ) , lung ( 1 ) , bladder ( 1 ) , breast ( 1 ) ] , the dose-response curves of s 10036 ( 0-100 microm ) were similar to those obtained with equimolar concentrations of bcnu and ccnu ; | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
23,
29
]
} | {
"id": "C0025202",
"name": "melanoma",
"pos": [
43,
51
]
} |
infants and children with symptomatic human immunodeficiency virus ( hiv ) infection frequently develop neurologic disease with symptoms and signs of acquired microcephaly , developmental delays , encephalopathy , pyramidal tract signs , and less often , movement disorders and ataxia . | nichd_parent_of | {
"id": "C0026650",
"name": "movement disorders",
"pos": [
255,
273
]
} | {
"id": "C0004134",
"name": "ataxia",
"pos": [
278,
284
]
} |
the palpebral fissure length was 1.94 +/- 0.17 cm ( mean +/- standard deviation ( sd ) ) and the head circumference was 34.0 +/- 1.3 cm ( mean +/- sd ) . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
22,
28
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
97,
115
]
} |
for secondary -- after initial infarction -- prevention of cardiovascular complications , the administration of aspirin and other antiplatelet agents has consistently decreased the rate of nonfatal myocardial infarction , overall mortality , or both . | nichd_parent_of | {
"id": "C0021308",
"name": "infarction",
"pos": [
31,
41
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
198,
219
]
} |
in a similar manner , individual characteristics of children at any age ( e.g. , maltreatment , at-risk status , etc . ) may also heighten their vulnerability to certain risks which require special consideration by researchers . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
22,
32
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
52,
60
]
} |
igg subclass-containing cells in the human large bowel of normal controls , non-ibd colitis , and ulcerative colitis . | nichd_parent_of | {
"id": "C0009319",
"name": "colitis",
"pos": [
84,
91
]
} | {
"id": "C0009324",
"name": "ulcerative colitis",
"pos": [
98,
116
]
} |
in non-ibd colitis , the numbers of igg1- and igg2-containing cells were increased compared to the controls , but the increases were less than uc , and there was no difference in the proportion of igg subclass compared to normal controls . | nichd_parent_of | {
"id": "C0009319",
"name": "colitis",
"pos": [
11,
18
]
} | {
"id": "C0009324",
"name": "uc",
"pos": [
143,
145
]
} |
psychiatric disorders associated with hiv infection include organic mental disorders , substance abuse disorder , affective disorders , adjustment disorders , anxiety disorders , and personality disorders . | nichd_parent_of | {
"id": "C0004936",
"name": "psychiatric disorders",
"pos": [
0,
21
]
} | {
"id": "C0003469",
"name": "anxiety disorders",
"pos": [
159,
176
]
} |
the increased sensitivity of aged mice to invasive bacterial infection documented in this series of experiments accords well with human epidemiologic experience and demonstrates the appropriateness of the model for continued investigations of sepsis in the aged . | nichd_parent_of | {
"id": "C0004623",
"name": "bacterial infection",
"pos": [
51,
70
]
} | {
"id": "C0036690",
"name": "sepsis",
"pos": [
243,
249
]
} |
as a first step towards the serological study of the epidemiology of hpv , we have synthesized the entire amino acid sequences of the 2 major viral capsid proteins of hpv type 16 , l1 and l2 , as a set of 66 synthetic 20-residue peptides with an overlap of 5 amino acids . | nichd_parent_of | {
"id": "C0021344",
"name": "hpv",
"pos": [
69,
72
]
} | {
"id": "C0999806",
"name": "hpv type 16",
"pos": [
167,
178
]
} |
( 2 ) metabolic myocardial radiopharmaceuticals have the potential to identify metabolic alterations unique to a given intrinsic cardiac disease ( e.g . cardiomyopathies ) , to assess acute metabolic changes or in delineating a specific chronic metabolic defect ( e.g . coronary artery disease ) . | nichd_parent_of | {
"id": "C0018799",
"name": "cardiac",
"pos": [
129,
136
]
} | {
"id": "C0878544",
"name": "cardiomyopathies",
"pos": [
153,
169
]
} |
the average values of propagation velocity in different types of tumors are found as 2106 , 2304 , 2677.5 , and 3586 m/s with 1.49 % , 1.04 % , and 0.74 % standard deviation in giant cell , lymphoma , chondro sarcoma , and osteogenic sarcoma , respectively . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
209,
216
]
} | {
"id": "C0029463",
"name": "osteogenic sarcoma",
"pos": [
223,
241
]
} |
a small number of bacterial agents , including enterotoxigenic escherichia coli ( etec ) , enteropathogenic e. coli ( epec ) , shigella and vibrio cholerae 01 and one virus , rotavirus , combine to cause a major proportion of the diarrheal illness of public health importance worldwide . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
"pos": [
167,
172
]
} | {
"id": "C0035870",
"name": "rotavirus",
"pos": [
175,
184
]
} |
vaccines to prevent hepatitis a -- both killed and live attenuated vaccines -- are undergoing clinical trials and may become available in the next 5 years . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccines",
"pos": [
0,
8
]
} | {
"id": "C0042211",
"name": "live",
"pos": [
51,
55
]
} |
these few cases were largely associated with oral vaccine and despite their small number have led to a reconsideration of killed vaccine as a public health measure in the united states . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
50,
57
]
} | {
"id": "C0042212",
"name": "killed vaccine",
"pos": [
122,
136
]
} |
further immune dysfunction was evident by the inability of t cells from mice with gvhd to generate a ctl response to h-2 alloantigens . | nichd_parent_of | {
"id": "C0021053",
"name": "immune dysfunction",
"pos": [
8,
26
]
} | {
"id": "C0018133",
"name": "gvhd",
"pos": [
82,
86
]
} |
interest has developed in surgically dividing the accessory pathway in patients with arrhythmias poorly controlled with medications or at risk for potentially fatal tachyarrhythmias . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
85,
96
]
} | {
"id": "C0080203",
"name": "tachyarrhythmias",
"pos": [
165,
181
]
} |
prior to serological investigation viruses from a second group of 35 patients were typed by dot blot hybridization with hpv-1 and hpv-2 dna . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
35,
42
]
} | {
"id": "C0021344",
"name": "hpv",
"pos": [
130,
133
]
} |
thirty-three patients , 8 an , 17 bulimia nervosa ( bn ) , and 8 eating disorder not otherwise specified ( ednos ) , were evaluated by bone densitometry ( radius , spine , femur ) to determine the prevalence and distribution of osteoporosis and the role of physical parameters , exercise and estrogen . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
122,
131
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
257,
265
]
} |
all three diagnostic subgroups had evidence of decreased bone density , worst in the ednos subgroup and least in the bn subgroup . | nichd_parent_of | {
"id": "C0013473",
"name": "ednos",
"pos": [
85,
90
]
} | {
"id": "C2267227",
"name": "bn",
"pos": [
117,
119
]
} |
the test procedure is divided into a control training session and a control evaluation session . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
9,
18
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
76,
86
]
} |
associations between antibodies themselves and the paucity of evidence for direct pathogenetic effects in many cases leave open the possibility that antinuclear antibodies are clues to aetiology , reporters of a past event initiating both disease and autoantibody production . | nichd_parent_of | {
"id": "C0003241",
"name": "antibodies",
"pos": [
21,
31
]
} | {
"id": "C0003243",
"name": "antinuclear antibodies",
"pos": [
149,
171
]
} |
many of these alterations parallel those observed in human patients suffering from cancer cachexia making canine lymphoma a potential model for further study of the pathogenesis and therapy of cancer cachexia . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
83,
89
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
113,
121
]
} |
among the variety of diseases in which the leukotrienes may play a symptomatic or causative role is the dermatological condition psoriasis , a chronic proliferative disease of the skin . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
21,
29
]
} | {
"id": "C0037274",
"name": "dermatological condition",
"pos": [
104,
128
]
} |
among the variety of diseases in which the leukotrienes may play a symptomatic or causative role is the dermatological condition psoriasis , a chronic proliferative disease of the skin . | nichd_parent_of | {
"id": "C0037274",
"name": "dermatological condition",
"pos": [
104,
128
]
} | {
"id": "C0033860",
"name": "psoriasis",
"pos": [
129,
138
]
} |
histopathologic study of the lung in patients suffering from complications revealed that destruction of the collateral vessels characterized by wide lumen and weak walls is responsible for the postoperative bleeding . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
"pos": [
61,
74
]
} | {
"id": "C0032788",
"name": "postoperative bleeding",
"pos": [
193,
215
]
} |
the first patient in this series , a 38-year-old woman , is the first patient in whom refractory atrioventricular node reentry tachycardia was cured surgically by a procedure designed to treat this arrhythmia . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
165,
174
]
} | {
"id": "C0087111",
"name": "treat",
"pos": [
187,
192
]
} |
these results support our procedure of performing preoperative diagnostics in order to evaluate local operability and resectability only in patients with bad physical condition . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
26,
35
]
} | {
"id": "C0220825",
"name": "evaluate",
"pos": [
87,
95
]
} |
the eight control children , who did not manifest symptoms of airway obstruction , had longer durations of intubation than did the infants who developed subglottic stenosis . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
18,
26
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
131,
138
]
} |
children , particularly infants , require large oral doses of cyclosporine to achieve immunosuppression after liver transplantation . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
0,
8
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
24,
31
]
} |
children and infants require large oral doses of cyclosporine because of the limited absorptive surface area of their intestines . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
0,
8
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
13,
20
]
} |
in other patients , the tumor appears on the ct scan as a hyperdense mass with well-defined margins and homogenous contrast enhancement ; | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
24,
29
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
69,
73
]
} |
there is a long standing position that pain , and especially chronic pain , may arise from psychological mechanisms of defence . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
39,
43
]
} | {
"id": "C0150055",
"name": "chronic pain",
"pos": [
61,
73
]
} |
the similarity scores of comparisons between a paramecium mt dna encoded protein , cytochrome b for example , and the homologous protein from a group of organisms as diverse as other protozoans , vertebrates , fungi , plants , and prokaryotes were all about the same . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
153,
162
]
} | {
"id": "C0016832",
"name": "fungi",
"pos": [
210,
215
]
} |
although technology is most commonly viewed in terms of equipment and procedures , the growing cost and complexity of drug therapy has made even this technology the target of assessment . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
70,
80
]
} | {
"id": "C0013216",
"name": "drug therapy",
"pos": [
118,
130
]
} |
pneumocystis carinii pneumonia is an important infection in the immunocompromised host , and the rate of symptomatic infections has risen dramatically with the advent of immunosuppressive therapies and infections with the human immunodeficiency virus ( hiv ) . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
47,
56
]
} | {
"id": "C0019693",
"name": "infections",
"pos": [
202,
212
]
} |
third , the expression of cd34 in malignancies appears to parallel normal cellular expression : of hematopoietic malignancies , some acute leukemias and chronic myelogenous leukemia blasts are cd34+ , but chronic lymphois leukemias , lymphomas , myelomas and non-hematopoietic malignancies are uniformly cd34- . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
34,
46
]
} | {
"id": "C0024299",
"name": "lymphomas",
"pos": [
234,
243
]
} |
a sample of children in the toddler age group was surveyed in denver , co , to determine the prevalence of giardia lamblia and to identify risk factors for the intestinal disease . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
12,
20
]
} | {
"id": "C0682053",
"name": "toddler age group",
"pos": [
28,
45
]
} |
fractures of the optic canal could be demonstrated by computed tomography in six cases and fractures of the orbital apex in another three cases . | nichd_parent_of | {
"id": "C0016658",
"name": "fractures",
"pos": [
0,
9
]
} | {
"id": "C0029184",
"name": "fractures",
"pos": [
91,
100
]
} |
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