text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
in these patients the incidence of panic attacks is higher , anxiety is more marked , and there are more often additional anxiety disorders ( generalised anxiety , sociophobia ) . | nichd_parent_of | {
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"name": "anxiety disorders",
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122,
139
]
} | {
"id": "C0270549",
"name": "generalised anxiety",
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} |
the number of sphenoid fractures not only exceeded those that involved the other bones of the base of the skull , including the temporal bone , but also exceeded the number of fractures of the cranial vault that could be identified with ct . | nichd_parent_of | {
"id": "C0016658",
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} | {
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in congenital orbital abnormalities and inflammatory diseases , ct readily detected ocular malformations ( microphthalmos and colobomata ) . | nichd_parent_of | {
"id": "C0000768",
"name": "congenital",
"pos": [
3,
13
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} | {
"id": "C0026010",
"name": "microphthalmos",
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an asymptomatic history , surgical stage i disease , lymphocytic thymoma cell type , and complete resection favorably influenced prognosis . | nichd_parent_of | {
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} | {
"id": "C0015250",
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in conjunction with total parathyroidectomy , this procedure has been used to treat patients with primary and secondary hyperparathyroidism who have generalized parathyroid hyperplasia . | nichd_parent_of | {
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clinical signs of synovitis , such as pain , range of motion and knee circumference , also improved . | nichd_parent_of | {
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} | {
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a 22 x 23 cm multiloculated tumour was visualized by ultrasonography , and surgery revealed a lymphangioma of mesenteric origin . | nichd_parent_of | {
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"name": "tumour",
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} | {
"id": "C0024221",
"name": "lymphangioma",
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thyrotropin receptor antibodies associated with post-operative relapse of thyrotoxicosis in a pregnancy complicated by neonatal thyrotoxicosis . | nichd_parent_of | {
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"name": "thyrotoxicosis",
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} | {
"id": "C0158983",
"name": "neonatal thyrotoxicosis",
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119,
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the use of prophylactic antibiotics , therefore , is indicated both in high-risk patients having nonelective cesarean section and in low-risk patients having elective repeat cesarean section . | nichd_parent_of | {
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"name": "cesarean section",
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109,
125
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} | {
"id": "C0473296",
"name": "elective",
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166
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} |
applications of salivary gland fna include ( 1 ) identification of nonneoplastic lesions that may respond to nonsurgical management , ( 2 ) identification of neoplasms that represent lymph node metastases rather than primary lesions of the salivary gland , ( 3 ) preliminary identification of lymphomas , and ( 4 ) preli... | nichd_parent_of | {
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167
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} | {
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"name": "malignant neoplasms",
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infection was detected in 59 % of patients overall , compared with 87.5 % of patients with pelvic inflammatory disease and 39.1 % of pregnant patients . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
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0,
9
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} | {
"id": "C0242172",
"name": "pelvic inflammatory disease",
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91,
118
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} |
long-term immunosuppression is followed by an increase of malignancies ( skin cancer , lymphomas and kaposi 's sarkoma ) . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
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58,
70
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} | {
"id": "C0024299",
"name": "lymphomas",
"pos": [
87,
96
]
} |
the overall mortality is low ( less than 1 % ) , but may be strikingly higher in children at risk : babies less than one month of age , preterm babies , infants with congenital heart- or pre-existent respiratory diseases , and those with severe immunodeficiency syndromes . | nichd_parent_of | {
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"name": "children",
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81,
89
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} | {
"id": "C0021270",
"name": "infants",
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153,
160
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} |
to test the fidelity of the pb-pk lactation model , a multiday inhalation exposure study was conducted from days 3 to 14 of lactation and a drinking water study , from days 3 to 21 of lactation . | nichd_parent_of | {
"id": "C0004927",
"name": "conducted",
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93,
102
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} | {
"id": "C0006147",
"name": "lactation",
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184,
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} |
therefore , to understand some of the quantitative and qualitative differences between proteins of human and male rat urine which confer apparent resistance to hdn in humans , urinary proteins of male f344 rats ( ca . 3 months old ) and normal human males were compared by cation exchange , gel filtration , sds-page , a... | nichd_parent_of | {
"id": "C0205556",
"name": "qualitative",
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66
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} | {
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data from the thai demographic and health survey , conducted in 1987 , confirm evidence from earlier surveys that the decline in the duration of breastfeeding evident during the 1970s came largely to a standstill in the 1980s . | nichd_parent_of | {
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"name": "conducted",
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51,
60
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} | {
"id": "C0006147",
"name": "breastfeeding",
"pos": [
145,
158
]
} |
the abbott tdx fluorescence polarization immunoassay ( fpia ) procedure for measuring cyclosporine a ( csa ) was evaluated and compared with the sandoz polyclonal radioimmunoassay ( csa ria kit ) method . | nichd_parent_of | {
"id": "C0184661",
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62,
71
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} | {
"id": "C0220825",
"name": "evaluated",
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113,
122
]
} |
a diffusely enlarged thyroid gland in the elderly is most often caused by a multinodular goiter . | nichd_parent_of | {
"id": "C0018021",
"name": "enlarged thyroid gland",
"pos": [
12,
34
]
} | {
"id": "C0342208",
"name": "multinodular goiter",
"pos": [
76,
95
]
} |
clinical signs include anorexia , vomiting , diarrhea , hemolytic anemia , kidney dysfunction , and possible liver and pancreatic abnormalities . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0003123",
"name": "anorexia",
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23,
31
]
} |
clinical signs include anorexia , vomiting , diarrhea , hemolytic anemia , kidney dysfunction , and possible liver and pancreatic abnormalities . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0042963",
"name": "vomiting",
"pos": [
34,
42
]
} |
treatments that have proven efficacious include fluid diuresis , blood transfusions as needed , general supportive care , and removal of the source of zinc . | nichd_parent_of | {
"id": "C0087111",
"name": "treatments",
"pos": [
0,
10
]
} | {
"id": "C0005841",
"name": "blood transfusions",
"pos": [
65,
83
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} |
all rabbits in group a were protected from symptoms of disease and remained alive , whereas two rabbits in group b developed clinical signs and one died . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
125,
139
]
} | {
"id": "C0011065",
"name": "died",
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148,
152
]
} |
the characteristics of muscle mass ( carcass weight , dressing percentage and proportion of lean meat ) were positively correlated with creatinine and with the total peak area or peak amplitude of growth hormone . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
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4,
19
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
45,
51
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} |
results revealed that most of the sophisticated procedures such as colonoscopy , ercp ( especially when they included therapeutic endoscopical methods ) varied largely in time . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
48,
58
]
} | {
"id": "C0087111",
"name": "therapeutic",
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118,
129
]
} |
arterial oxygenation , as measured by serial arterial blood gases ( abgs ) and in vivo polarographic pao2 during the rapid sequence induction of general endotracheal anesthesia , was evaluated in 20 asa physical class iv subjects undergoing elective coronary artery bypass grafting ( cabg ) . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
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183,
192
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} | {
"id": "C0031809",
"name": "physical",
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203,
211
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} |
routine follow-up included at least 5 physical examinations with measurement of length , weight and head circumference at the beginning of caffeine therapy , at mid therapy , at the end of the therapy and at 3 and 6 months after therapy . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
80,
86
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
100,
118
]
} |
the distribution of the infants on the growth curves according to weight , length and head circumference showed a regular increase in growth parameters . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
75,
81
]
} | {
"id": "C0262499",
"name": "head circumference",
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86,
104
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} |
in a study of suspected cases of child sexual abuse , 22 persons ( 21 men and one woman ) were identified as probable perpetrators according to the child psychiatric evaluation . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
57,
64
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
148,
153
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} |
disease , addiction , sexual frustration , unwanted separation , ageing and adolescence were identified as factors which in individual cases seemed to have influenced a person 's predisposition to abuse children sexually . | nichd_parent_of | {
"id": "C0027361",
"name": "person 's",
"pos": [
169,
178
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
203,
211
]
} |
although seven tumors were predominantly intraparenchymal masses with calcification and cyst formation , five were intra- or juxtaventricular . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
15,
21
]
} | {
"id": "C0577559",
"name": "masses",
"pos": [
58,
64
]
} |
the neoplasms were categorized into two groups on the basis of t1-weighted mr signal intensity ( relative to brain ) : high-signal-intensity masses ( short t1 ) and low-signal-intensity masses ( long t1 ) . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
4,
13
]
} | {
"id": "C0577559",
"name": "masses",
"pos": [
186,
192
]
} |
serious arrhythmia was documented in 2 patients , cardiac standstill in 1 and complete atrioventricular block in the other . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
8,
18
]
} | {
"id": "C0151517",
"name": "complete atrioventricular block",
"pos": [
78,
109
]
} |
data from 204 children and infants who underwent aortic balloon valvuloplasty between 1982 and 1986 , reported to the valvuloplasty and angioplasty of congenital anomalies registry , were reviewed . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
14,
22
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
27,
34
]
} |
the adult form of tay-sachs disease , adult gm2 gangliosidosis , is an autosomal recessive neurological disorder caused by a partial deficiency of beta-hexosaminidase a . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
28,
35
]
} | {
"id": "C0027765",
"name": "neurological disorder",
"pos": [
91,
112
]
} |
one of the major modifiable risk factors for cardiovascular disease , hypertension , is a leading cause of stroke , kidney disease , and diseases of the heart and coronary circulation . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular disease",
"pos": [
45,
67
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
70,
82
]
} |
one of the major modifiable risk factors for cardiovascular disease , hypertension , is a leading cause of stroke , kidney disease , and diseases of the heart and coronary circulation . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular disease",
"pos": [
45,
67
]
} | {
"id": "C0018799",
"name": "diseases of the heart",
"pos": [
137,
158
]
} |
pregnancy complications as a result of trauma occurred in 18 of 205 patients ( 8.8 % ) : premature labor ( n = 10 ) , placental separation ( n = 5 ) , fetal injury ( n = 1 ) , and fetal death ( n = 2 ) . | nichd_parent_of | {
"id": "C0032962",
"name": "pregnancy",
"pos": [
0,
9
]
} | {
"id": "C0022876",
"name": "premature labor",
"pos": [
89,
104
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} |
pregnancy complications as a result of trauma occurred in 18 of 205 patients ( 8.8 % ) : premature labor ( n = 10 ) , placental separation ( n = 5 ) , fetal injury ( n = 1 ) , and fetal death ( n = 2 ) . | nichd_parent_of | {
"id": "C0032962",
"name": "pregnancy",
"pos": [
0,
9
]
} | {
"id": "C0000832",
"name": "placental separation",
"pos": [
118,
138
]
} |
the prevalence of plaque reduction neutralizing antibodies to den-1 and den-2 viruses was measured in 1,295 individuals ( children and adults ) . | nichd_parent_of | {
"id": "C0027361",
"name": "individuals",
"pos": [
108,
119
]
} | {
"id": "C0008059",
"name": "children",
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122,
130
]
} |
this study compares the traditional method ( tm ) of evaluating ward performance on the surgical clerkship with four structured , single-observer methods ( ssom ) of evaluating the clinical skills demonstrated in patient workups , progress notes , physical examination , and technical performance . | nichd_parent_of | {
"id": "C0220825",
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63
]
} | {
"id": "C0031809",
"name": "physical examination",
"pos": [
248,
268
]
} |
creutzfeldt-jakob disease patients with congophilic kuru plaques have the missense variant prion protein common to gerstmann-straussler syndrome . | nichd_parent_of | {
"id": "C0022336",
"name": "creutzfeldt-jakob disease",
"pos": [
0,
25
]
} | {
"id": "C0376329",
"name": "variant prion protein",
"pos": [
83,
104
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} |
our findings show that cjd with congophilic kuru plaques should be categorized as belonging to gerstmann-straussler syndrome , not cjd , and also suggest that the variant prion protein with leu102 is closely related to the amyloidogenesis seen in subjects with congophilic kuru plaques . | nichd_parent_of | {
"id": "C0022336",
"name": "cjd",
"pos": [
23,
26
]
} | {
"id": "C0376329",
"name": "variant",
"pos": [
163,
170
]
} |
we report severe congenital encephalopathy and profound hypotonia associated with necrotizing myopathy , cardiomyopathy , and cataracts in 3 infants , including 2 sisters . | nichd_parent_of | {
"id": "C0026848",
"name": "myopathy",
"pos": [
94,
102
]
} | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
105,
119
]
} |
twenty six children with down 's syndrome had acute myeloblastic leukaemia and were significantly younger and had a higher percentage of the megakaryocytic and erythroid subtypes of acute myeloblastic leukaemia than the 713 controls . | nichd_parent_of | {
"id": "C0023467",
"name": "acute myeloblastic leukaemia",
"pos": [
46,
74
]
} | {
"id": "C0023440",
"name": "erythroid",
"pos": [
160,
169
]
} |
the 14 remaining monkeys survived rvf viral infection but , 7 showed clinical signs of illness characterized by diminished food intake , cutaneous petechiae , and occasional vomiting . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
69,
83
]
} | {
"id": "C0042963",
"name": "vomiting",
"pos": [
174,
182
]
} |
the purpose of this naturalistic study was to describe sleep and wakefulness ( s/w ) within the limits afforded by brief behavioral observations and to examine homeostasis and diurnal rhythmicity of s/w as a function of psychoactive drug intake . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
121,
131
]
} | {
"id": "C0037313",
"name": "s/w",
"pos": [
199,
202
]
} |
numerous studies performed over the past 5 years have indicated an association between hiv infection and other sexually transmitted diseases ( stds ) , particularly those involving genital ulceration . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
91,
100
]
} | {
"id": "C0036916",
"name": "sexually transmitted diseases",
"pos": [
111,
140
]
} |
the results of a slimming treatment in which the main features were : energy intake according to expected body weight for height ( normocaloric ) , exercise , education and psychological support , are evaluated after one year of experience . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
54,
62
]
} | {
"id": "C0005910",
"name": "body weight",
"pos": [
106,
117
]
} |
a case of low pressure cardiac tamponade is reported in which hypovolaemia altered the clinical findings of tamponade and complicated the diagnosis . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
87,
104
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
138,
147
]
} |
in control persons the values of w/s increased with age , whereas in families with a-t no significant differences in this parameter were noted between children and parents . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
11,
18
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
151,
159
]
} |
molecular studies of von willebrand disease : reduced von willebrand factor biosynthesis , storage , and release in endothelial cells derived from patients with type i von willebrand disease . | nichd_parent_of | {
"id": "C0042974",
"name": "von willebrand disease",
"pos": [
21,
43
]
} | {
"id": "C1264039",
"name": "type i von willebrand disease",
"pos": [
161,
190
]
} |
a procedure for measuring auditory and audio-visual speech-reception thresholds for sentences in noise : rationale , evaluation , and recommendations for use . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
2,
11
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
117,
127
]
} |
the relevance of the dna index ( di ) to malignancy grading and the relationships between mitotic score , ki-67 score , and the proportion of cells in the g1-phase ( g1pf ) of the cell cycle , as proliferative indicators , were investigated in benign ( n = 8 ) and malignant ( n = 46 ) soft tissue sarcomas . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
41,
51
]
} | {
"id": "C1261473",
"name": "soft tissue sarcomas",
"pos": [
286,
306
]
} |
correlation between histologic grade of malignancy and copy number of c-erbb-2 gene in breast carcinoma . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
40,
50
]
} | {
"id": "C0678222",
"name": "of",
"pos": [
67,
69
]
} |
to study the molecular origin of the altered regulation of butyrylcholinesterase ( buche ) in nervous system tumors , buche complementary dna ( cdna ) sequences from human glioblastoma and neuroblastoma cdna libraries were compared with buche cdnas from normal fetal and adult tissues . | nichd_parent_of | {
"id": "C0027766",
"name": "nervous system tumors",
"pos": [
94,
115
]
} | {
"id": "C0027819",
"name": "neuroblastoma",
"pos": [
189,
202
]
} |
the serum factor inducing hemorrhagic necrosis of transplantable tumors [ tumor necrosis factor ( tnf ) ] , and the macrophage hormone associated with cachexia in cancer and certain infectious diseases [ cachectin ] are known to be the same protein . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
65,
71
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
163,
169
]
} |
one fracture occurred through a perforation site and had an associated fracture of the femoral component . | nichd_parent_of | {
"id": "C0016658",
"name": "fracture",
"pos": [
4,
12
]
} | {
"id": "C0015802",
"name": "fracture",
"pos": [
71,
79
]
} |
although only a small number of children with cerebral palsy have indications for surgical treatment of dynamic or structural upper-extremity deformities , orthopedic surgery does improve function and appearance of the involved hand , particularly in spastic hemiplegia . | nichd_parent_of | {
"id": "C0007789",
"name": "cerebral palsy",
"pos": [
46,
60
]
} | {
"id": "C0154694",
"name": "spastic hemiplegia",
"pos": [
251,
269
]
} |
the three common causes of urinary obstruction in the newborn are ureteropelvic obstruction , posterior urethral valves , and ureteroceles . | nichd_parent_of | {
"id": "C0178879",
"name": "urinary obstruction",
"pos": [
27,
46
]
} | {
"id": "C0521619",
"name": "ureteropelvic",
"pos": [
66,
79
]
} |
nineteen patients with raynaud 's phenomenon ( 12 suffering from generalized scleroderma [ gs ] and seven from primary raynaud 's phenomenon [ pr ] and seven cold-tolerant healthy women underwent a cooling challenge with combined body and finger cooling . | nichd_parent_of | {
"id": "C0034735",
"name": "raynaud 's phenomenon",
"pos": [
23,
44
]
} | {
"id": "C0151445",
"name": "primary raynaud 's phenomenon",
"pos": [
111,
140
]
} |
the number of bacteremias and other central and arterial line-related infections approximated wound infection in incidence at 6.8/100 patients . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
70,
80
]
} | {
"id": "C0043241",
"name": "wound infection",
"pos": [
94,
109
]
} |
the level of 5-hiaa was significantly decreased in children early and late after the febrile convulsion as compared with the convulsion-free group , but the hva level was reduced only early after the febrile convulsion . | nichd_parent_of | {
"id": "C0036572",
"name": "convulsion",
"pos": [
93,
103
]
} | {
"id": "C0009952",
"name": "febrile convulsion",
"pos": [
200,
218
]
} |
exposure to aerosol resulted in more severe clinical signs characterised by high temperatures , dyspnoea , anorexia and coughing ; | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
44,
58
]
} | {
"id": "C0013404",
"name": "dyspnoea",
"pos": [
96,
104
]
} |
exposure to aerosol resulted in more severe clinical signs characterised by high temperatures , dyspnoea , anorexia and coughing ; | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
44,
58
]
} | {
"id": "C0003123",
"name": "anorexia",
"pos": [
107,
115
]
} |
exposure to aerosol resulted in more severe clinical signs characterised by high temperatures , dyspnoea , anorexia and coughing ; | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
44,
58
]
} | {
"id": "C0010200",
"name": "coughing",
"pos": [
120,
128
]
} |
this high-resolution method is a tool worthy of consideration for the research of csf proteins and disease-specific changes in different neurological disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
99,
106
]
} | {
"id": "C0027765",
"name": "neurological disorders",
"pos": [
137,
159
]
} |
oi fibroblasts remain on a basal level except for fibroblasts from oi type iv patients which seem to approach normal levels . | nichd_parent_of | {
"id": "C0029434",
"name": "oi",
"pos": [
0,
2
]
} | {
"id": "C0268363",
"name": "oi type iv",
"pos": [
67,
77
]
} |
typical sonographical features are polyhydramnios , hypoplasia of lungs , foetal akinesia , reduced length of proximal and distal extremities and a striking discrepancy between biparietal and abdominal diameter . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
22,
30
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
100,
106
]
} |
comparison of the hib m43p+ pilin amino acid sequence with those of pilins of other bacteria revealed strong conservation of amino- and carboxy-terminal regions in m43p+ and escherichia coli f17 , type 1c , and several members of the p pili family , as well as klebsiella pneumoniae type 3 mr/k , bordetella pertussis se... | nichd_parent_of | {
"id": "C0004611",
"name": "bacteria",
"pos": [
84,
92
]
} | {
"id": "C0006017",
"name": "bordetella pertussis",
"pos": [
297,
317
]
} |
on the other hand , all the tumors showed rapid growth and comprised a large mass in the lung parenchyma . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
28,
34
]
} | {
"id": "C0577559",
"name": "a",
"pos": [
103,
104
]
} |
the individual ratios between oxybuprocaine- and saline-instilled eyes in the niddm and iddm patients differed significantly from those in the healthy controls ( mean ratios : 2.6 , 1.9 , and 1.0 , respectively ; | nichd_parent_of | {
"id": "C0011849",
"name": "niddm",
"pos": [
78,
83
]
} | {
"id": "C0011854",
"name": "iddm",
"pos": [
88,
92
]
} |
the permeability ratios and the percentage glycosylated hemoglobin ( hbalc ) were linearly correlated in the niddm patients but not in the iddm patients ( r = 0.73 , p less than 0.001 , and r = 0.09 , p greater than 0.68 , respectively ) . | nichd_parent_of | {
"id": "C0011849",
"name": "niddm",
"pos": [
109,
114
]
} | {
"id": "C0011854",
"name": "iddm",
"pos": [
139,
143
]
} |
in addition to the typical manifestations of diffuse ( truncal ) scleroderma , including involvement of the esophagus , lungs and muscles , there were two unusual findings : large , non-sclerosing areas on the trunk simulating the disabling type of circumscribed scleroderma and high titers of anticentromere antibodies ... | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
"pos": [
65,
76
]
} | {
"id": "C0036420",
"name": "circumscribed scleroderma",
"pos": [
249,
274
]
} |
reversing the leveling procedure in each icu reduced surgical unit accuracy to an unacceptable level ; | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
23,
32
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
53,
61
]
} |
surgical therapy consisted of total resection in 15 patients , subtotal resection in 1 patient , and biopsy in 14 patients . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical",
"pos": [
0,
8
]
} | {
"id": "C0015250",
"name": "total resection",
"pos": [
66,
81
]
} |
in contrast , national birth statistics and other cross-sectional studies of these relationships suggests a decrease in mean birth weight and an increased incidence of low-weight births with parity among adolescent mothers . | nichd_parent_of | {
"id": "C0005612",
"name": "birth weight",
"pos": [
125,
137
]
} | {
"id": "C0024032",
"name": "low-weight births",
"pos": [
168,
185
]
} |
organisms of recent interest , such as bacillus , yersinia , campylobacter , listeria , sporothrix , giardia , cryptosporidium , and anisakis , are the foci of new investigations , as are the more familiar foodborne pathogens , salmonella , shigella , clostridium , staphylococcus , entamoeba and ascaris . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
0,
9
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
216,
225
]
} |
some foodborne organisms , such as parasitic protozoa , serve as hosts for unique bacterial and viral symbionts but also might become infected with mammalian viruses . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
15,
24
]
} | {
"id": "C0042776",
"name": "viruses",
"pos": [
158,
165
]
} |
failure to clear infectious virus may be due to inadequate inhibition of virus production by macrophages , a major reservoir of hiv infection . | nichd_parent_of | {
"id": "C0009450",
"name": "infectious",
"pos": [
17,
27
]
} | {
"id": "C0019693",
"name": "hiv infection",
"pos": [
128,
141
]
} |
hypersecretion of the pituitary glycoprotein hormone alpha-subunit has been reported in pituitary adenomas , particularly in clinically nonfunctioning tumors and somatotroph adenomas . | nichd_parent_of | {
"id": "C0032000",
"name": "pituitary adenomas",
"pos": [
88,
106
]
} | {
"id": "C0346302",
"name": "somatotroph adenomas",
"pos": [
162,
182
]
} |
macerated interspaces were characterized by a greater recovery of organisms with pathogenic potential , with staphylococcus aureus recovered from 36 % of patients , micrococcus sedentarius in 37 % , brevibacterium epidermidis in 54 % , corynebacterium minutissimum in 69 % , and pseudomonas species in 26 % . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
66,
75
]
} | {
"id": "C0450254",
"name": "pathogenic",
"pos": [
81,
91
]
} |
these findings suggest that leu-8/cd7 antigen deficiencies in skin lesions of mycosis fungoides/sezary syndrome do not represent generalized antigenic abnormalities of cd3+ t cells in other body compartments and that within the skin , these deficiencies are disease specific within individual patients with more than one... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
258,
265
]
} | {
"id": "C0037274",
"name": "dermatosis",
"pos": [
321,
331
]
} |
immunization of lupus mice with mab 3e10 inhibited production of native anti-dna antibodies , suppressed development of lupus kidney disease ( nephritis ) , and induced production of anti-anti-dna ( anti-id ) antibodies . | nichd_parent_of | {
"id": "C0022658",
"name": "of",
"pos": [
13,
15
]
} | {
"id": "C0027697",
"name": "nephritis",
"pos": [
143,
152
]
} |
an elisa procedure which utilized an avidin-peroxidase amplification reaction to detect and quantify the amount of fluid-phase biotinylated antigen bound to solid-phase antibody was developed to determine antibody association constants . | nichd_parent_of | {
"id": "C0005889",
"name": "fluid",
"pos": [
115,
120
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
205,
213
]
} |
this may be partly due to the nature of the vaccine virus , but because responses of adults were similar to those of leukemic children , it suggests also that both of these groups have impaired immune responses to vzv . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
"pos": [
52,
57
]
} | {
"id": "C0042338",
"name": "vzv",
"pos": [
214,
217
]
} |
interferon therapy of relapsed and refractory hodgkin 's disease : cancer and leukemia group b study 8652 . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
67,
73
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
87,
92
]
} |
a phase ii trial of alpha 2b-interferon in patients with relapsed or refractory hodgkin 's disease was conducted by the cancer and leukemia group b . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
120,
126
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
140,
145
]
} |
eleven patients with cpeo , including 5 who exhibited the complete triad of symptoms characteristic of the kearns-sayre syndrome ( i.e . cpeo , retinal degeneration and heart block ) had heteroplasmic mtdna with deletions ranging from 2.0 to 8.0 kb in length . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
85,
99
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
252,
258
]
} |
abuse often begins or escalates during pregnancy , and may result in pregnancy loss , preterm labor , low birth-weight , fetal injury , and fetal death . | nichd_parent_of | {
"id": "C0032972",
"name": "result",
"pos": [
59,
65
]
} | {
"id": "C0015927",
"name": "fetal death",
"pos": [
140,
151
]
} |
a free air temperature measurement method of predicting burns is less accurate , although , for brief exposures , a time-temperature integral of 1315 degrees c-second ( 2400 degrees f-second ) above body temperature correlates with heat transfer causing second-degree burns . | nichd_parent_of | {
"id": "C0006434",
"name": "burns",
"pos": [
56,
61
]
} | {
"id": "C0332687",
"name": "second-degree burns",
"pos": [
254,
273
]
} |
multiple regression analysis with a stepwise procedure was used to generate three predictive models for length of stay : ( 1 ) a model to be used before operation , ( 2 ) a model that combines preoperative and donor information , and ( 3 ) a model that takes preoperative , donor , and postoperative factors ( complete m... | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
45,
54
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
153,
162
]
} |
although five of these six children produced antibodies in response to hib polysaccharide protein conjugate vaccine , three of four given hib oligosaccharide crm conjugate vaccine required booster doses to respond , a pattern of response characteristic of infants less than 6 months of age . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
27,
35
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
256,
263
]
} |
aspirin has been shown to reduce the number of transient ischemic attacks ( tia ) , stroke and death in patients with multiple tia . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
84,
90
]
} | {
"id": "C0007787",
"name": "tia",
"pos": [
127,
130
]
} |
in post-phlebitic syndrome and , more particularly , in trophic disorders , they play a major part , and ought to be the object of thorough investigation , using clinical examination , the doppler and phlebography . | nichd_parent_of | {
"id": "C0220825",
"name": "investigation",
"pos": [
140,
153
]
} | {
"id": "C0031809",
"name": "clinical",
"pos": [
162,
170
]
} |
because of this , a new operation , designated the vm-plasty , was devised specifically for correction of postburn syndactyly , and this procedure was evaluated in 24 deformities . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
137,
146
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
151,
160
]
} |
pain literature is examined to demonstrate the significance of family factors in the etiology , perpetuation and treatment of chronic pain . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
0,
4
]
} | {
"id": "C0150055",
"name": "chronic pain",
"pos": [
126,
138
]
} |
the isometric twitch characteristics and passive tension-length relationship were studied in the soleus and extensor digitorum longus muscles of anaesthetized rats injected for increasing periods with triiodothyronine . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
21,
36
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
57,
63
]
} |
with continued growth , the scaffolding along which the tumor infiltrates is destroyed , growth becomes expansile , and the lymphomatous mass resembles other renal neoplasms that enlarge by appositional growth . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
56,
61
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
137,
141
]
} |
thermography is proposed as a simple and harmless procedure for the follow-up of bone and soft tissue tumors after conservative treatments . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
50,
59
]
} | {
"id": "C0087111",
"name": "treatments",
"pos": [
128,
138
]
} |
although the assay of hr from whole blood may be a very specific indicator of cell sensitivity in the field of allergy research , the present findings indicate that the conventional methods for diagnosing flour allergy in bakers such as inhalative provocation tests can not be replaced by this in vitro technique . | nichd_parent_of | {
"id": "C0430022",
"name": "methods",
"pos": [
182,
189
]
} | {
"id": "C0022885",
"name": "tests",
"pos": [
260,
265
]
} |
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