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the author describes and contrasts these patterns , and believes that this might be helpful in the differential diagnosis of cervical headaches and migraine .
nichd_parent_of
{ "id": "C0018681", "name": "headaches", "pos": [ 134, 143 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 148, 156 ] }
surgical debulking of tumors is a procedure whereby a surgically incurable malignant neoplasm is partially removed without curative intent in order to make subsequent therapy with drugs , radiation or other adjunctive measures more effective and , thereby , improve the length of survival .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 34, 43 ] }
{ "id": "C0543467", "name": "surgically", "pos": [ 54, 64 ] }
surgical debulking of tumors is a procedure whereby a surgically incurable malignant neoplasm is partially removed without curative intent in order to make subsequent therapy with drugs , radiation or other adjunctive measures more effective and , thereby , improve the length of survival .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 34, 43 ] }
{ "id": "C0013216", "name": "therapy", "pos": [ 167, 174 ] }
since the west berlin population includes a high percentage of turkish people , we can conclude from our case material that even those turkish children who were born in west berlin suffer from urolithiasis 2-2.5 times as often as german children of the same age-groups .
nichd_parent_of
{ "id": "C0027361", "name": "people", "pos": [ 71, 77 ] }
{ "id": "C0008059", "name": "children", "pos": [ 237, 245 ] }
the necessary method of treatment is thought to be an urgent operation with suturing the perforated ulcer and peritonization of all the ulcers found or a resection of the injured portion of the intestine , peritoneal dialysis , drainage of the thoracic lymph duct and intensive transfusion therapy in the postoperative p...
nichd_parent_of
{ "id": "C0087111", "name": "method", "pos": [ 14, 20 ] }
{ "id": "C0005841", "name": "transfusion", "pos": [ 278, 289 ] }
vaccinal virus was recovered for up to 16 days after vaccination from nasal secretions of all calves given live vaccine .
nichd_parent_of
{ "id": "C0042210", "name": "vaccinal", "pos": [ 0, 8 ] }
{ "id": "C0042211", "name": "live vaccine", "pos": [ 107, 119 ] }
we can recommend the use of modern detergents in pediatrics , they represent an important part of modern hygiene in childhood , especially in infancy .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 116, 125 ] }
{ "id": "C0231330", "name": "infancy", "pos": [ 142, 149 ] }
fields in which this procedure has proved of particular value are acute surgical emergencies , polytrauma , biliary surgery , post-operative complications , septic processes , palpable abdominal masses and the investigation and follow up of patients with tumours .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 21, 30 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 210, 223 ] }
thus the averaging technique may provide a non-invasive procedure to assess the successful outcome after operation for ventricular tachycardia .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 56, 65 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 105, 114 ] }
[ importance of cross reactions in evaluating the serological diagnosis of human brucellosis . ii . examination of brucellosis patients by the passive hemagglutination reaction using homologous and heterologous erythrocyte diagnostica ] .
nichd_parent_of
{ "id": "C0220825", "name": "evaluating", "pos": [ 35, 45 ] }
{ "id": "C0031809", "name": "of", "pos": [ 112, 114 ] }
in high-risk patients without clinical evidence of neoplasm , some benign squamous cells were cea positive , possibly indicating the presence of an undetected or developing cancer .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasm", "pos": [ 51, 59 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 173, 179 ] }
in this procedure approximately 10 ml cyclohexane was sprayed onto a limited area of the skin ( 5 cm2 ) to be evaluated .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 8, 17 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 110, 119 ] }
the abnormalities of respiratory movements may be reliable clinical signs of inspiratory muscle fatigue , particularly when accompanied by tachypnea and hypercapnia .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 59, 73 ] }
{ "id": "C0231835", "name": "tachypnea", "pos": [ 139, 148 ] }
however , hyponatremia within five days of onset of pneumonia occurred significantly more frequently in legionnaires ' disease ( p less than 0.0001 ) .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonia", "pos": [ 52, 61 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 104, 116 ] }
syndrome of anosmia with hypogonadotropic hypogonadism ( kallmann syndrome ) : clinical and laboratory studies in 23 cases .
nichd_parent_of
{ "id": "C0039082", "name": "syndrome", "pos": [ 0, 8 ] }
{ "id": "C0162809", "name": "kallmann syndrome", "pos": [ 57, 74 ] }
opsonic activity to three test organisms ( escherichia coli 286 and on 2 , and staphylococcus aureus ) and to 15 blood stream isolates from 14 patients was measured as serum-dependent uptake of heat-killed 14c-labeled bacteria by normal donor leukopheresis granulocytes in an in vitro assay and compared with results obt...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 31, 40 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 218, 226 ] }
the authors concluded that with halothane and increasing epi dose , sensitization constitutes a spectrum of arrhythmias , beginning with atrial and progressing to severe ventricular arrhythmias .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmias", "pos": [ 108, 119 ] }
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 170, 193 ] }
with a high index of suspicion , improving methods of diagnosis such as the immunoassays for b-hcg and ultrasonography may lower mortality rates by enabling more diagnoses to be made before rupture .
nichd_parent_of
{ "id": "C0430022", "name": "methods", "pos": [ 43, 50 ] }
{ "id": "C0041618", "name": "ultrasonography", "pos": [ 103, 118 ] }
apneas were rarely associated with significant o2 desaturation and were fewer in number than typically seen in a clinically significant sleep apnea syndrome .
nichd_parent_of
{ "id": "C0003578", "name": "apneas", "pos": [ 0, 6 ] }
{ "id": "C0037315", "name": "sleep apnea syndrome", "pos": [ 136, 156 ] }
antiperinuclear factors ( apf ) , studied in 90 patients suffering from psoriasis , were found in psoriasis without arthritis , in psoriasis with psoriatic arthritis and in psoriasis with true rheumatoid arthritis ( ra ) : respectively 57 , 36 and 43 p .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 116, 125 ] }
{ "id": "C0003872", "name": "psoriasis", "pos": [ 173, 182 ] }
antiperinuclear factors ( apf ) , studied in 90 patients suffering from psoriasis , were found in psoriasis without arthritis , in psoriasis with psoriatic arthritis and in psoriasis with true rheumatoid arthritis ( ra ) : respectively 57 , 36 and 43 p .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 116, 125 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 193, 213 ] }
vaccines prepared from live-attenuated viruses ( measles , mumps , rubella , and trivalent oral poliovirus ) can cause symptomatic viral infection of the nervous system , including measles encephalitis , which occurs in 1 of 1,000,000 vaccine recipients ;
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 39, 46 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 96, 106 ] }
the latter fraction showed a significant antimicrobial activity against gram-positive and gram-negative bacteria , fungi and yeasts .
nichd_parent_of
{ "id": "C0016832", "name": "fungi", "pos": [ 115, 120 ] }
{ "id": "C0043393", "name": "yeasts", "pos": [ 125, 131 ] }
evaluation of these records showed that there was a pattern of joint involvement and associated physical and clinical features specific to each strain and that such strain specificity was reproducible in groups of rats injected over periods up to 3 1/2 years .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 0, 10 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 96, 104 ] }
tumors typically appeared as masses of increased intensity on spin echo images and diminished intensity on inversion recovery images .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 0, 6 ] }
{ "id": "C0577559", "name": "masses", "pos": [ 29, 35 ] }
when rpg is used as the criterion for the detection of ileofemoral vein thrombosis and rv is used as the criterion for the detection of calf vein thrombosis , the combined techniques show improved sensitivity ( 92 % ) and specificity ( 93 % ) for the detection of all deep venous thromboses .
nichd_parent_of
{ "id": "C0042487", "name": "of", "pos": [ 52, 54 ] }
{ "id": "C0149871", "name": "deep venous thromboses", "pos": [ 268, 290 ] }
if the radiographic features are characteristic , and fine-needle biopsy finding negative , the diagnosis of round atelectasis can be made with assurance , and unnecessary procedures such as thoracotomy and pulmonary resection can be avoided .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 73, 80 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 96, 105 ] }
an influence of complete mechanical obstruction of the nasal passages was investigated in 6 apneic-free sons of fullblown sleep apnea patients and in 4 age-matched normal young adults without a familial history of sleep apnea .
nichd_parent_of
{ "id": "C0003578", "name": "apneic", "pos": [ 92, 98 ] }
{ "id": "C0037315", "name": "sleep apnea", "pos": [ 214, 225 ] }
we want to point out that meniere 's disease , though usually presenting itself at middle age , may well start in childhood as well as in infancy , and should be suspected whenever vomiting , without diarrhea , is associated with some hearing loss at any age -- no matter how young the patient is .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 114, 123 ] }
{ "id": "C0231330", "name": "infancy", "pos": [ 138, 145 ] }
two patients died of their disease , one died without evidence of neoplasm , and four were living and clinically free of tumor at last follow-up .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 27, 34 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 121, 126 ] }
in 9 of 16 patients having this procedure as part of an ileo-anal anastomosis ( with a pelvic ileal reservoir ) the functional results seemed to be similar to those obtained in 14 patients submitted to the same operation but with an endocavitary technique of rectal mucosectomy .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 32, 41 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 211, 220 ] }
the current results support the combination tumor theory , which means that both the carcinomatous and sarcomatous components are of common stem cell origin .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 44, 49 ] }
{ "id": "C0006826", "name": "carcinomatous", "pos": [ 85, 98 ] }
the technique and predictive value for survival of initial and restaging bone marrow examinations in small cell carcinoma ( scc ) of the lung were evaluated by 76 examinations of 72 patients .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 147, 156 ] }
{ "id": "C0031809", "name": "examinations of", "pos": [ 163, 178 ] }
after optimum techniques had been developed for transplantation and the feasibility of the procedure had been established in twenty-one rabbits , the capacity of the physeal transplants to prevent bone-bridge formation , growth arrest , and valgus deformity was evaluated in thirty-nine rabbits , three to four months ol...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 91, 100 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 262, 271 ] }
the ejection fraction decreased by greater than or equal to 0.01 and greater than or equal to 0.05 during exercise in 48 and 28 % , respectively , of the patients with coronary artery disease compared with only 8 and 2 % , respectively , of the patients with cardiomyopathy .
nichd_parent_of
{ "id": "C0018799", "name": "of the", "pos": [ 147, 153 ] }
{ "id": "C0878544", "name": "cardiomyopathy", "pos": [ 259, 273 ] }
the procedure is called cascade immunization because it involves repeated removal of antigens and production of further antisera directed against antigens in the remainder .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0020971", "name": "immunization", "pos": [ 32, 44 ] }
crude coal tar ( cct ) and certain photoreactive ingredients of cct are photosensitizing agents used in the treatment of skin diseases ( psoriasis , atopic eczema , etc . ) .
nichd_parent_of
{ "id": "C0037274", "name": "of skin diseases", "pos": [ 118, 134 ] }
{ "id": "C0033860", "name": "psoriasis", "pos": [ 137, 146 ] }
from behaviors noted in these children , together with symptoms found in published biographical and autobiographical accounts of the childhood of persons with multiple personality , a list of 20 behavioral signs was derived which should be of assistance in helping teachers and other professionals who have frequent cont...
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 146, 153 ] }
{ "id": "C0008059", "name": "children", "pos": [ 329, 337 ] }
it appears that in infant monkeys microgram amounts of c. difficile toxins a and b can produce a rapid quiet death , the cause of which is undetectable at necropsy , a situation pathologically reminiscent of crib death in human infants , although the possible clinical identity of these two conditions has yet to be esta...
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 109, 114 ] }
{ "id": "C0038644", "name": "crib death", "pos": [ 208, 218 ] }
these tumors have a particular tendency to occur in the genitourinary tract and are often mistaken clinically for malignancies .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 6, 12 ] }
{ "id": "C0006826", "name": "malignancies", "pos": [ 114, 126 ] }
group 1 ( n = 132 ) had simultaneous carotid endarterectomy and cab , group 2 ( n = 51 ) were patients having perioperative stroke following elective cab , and group 3 ( n = 169 ) had cab alone but had prior history of either asymptomatic cervical bruit , stroke/transient cerebral ischemic attack ( tia ) , or carotid e...
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 124, 130 ] }
{ "id": "C0007787", "name": "transient", "pos": [ 263, 272 ] }
our findings are most consistent with evidence that childhood and adult hypophosphatasia often represent clinical expression of the heterozygous state for alp deficiency which , when homozygous , results in the clinically severe , recessive , infantile form .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 52, 61 ] }
{ "id": "C0231330", "name": "infantile", "pos": [ 243, 252 ] }
in contrast , following active encouragement to adhere to the procedure , a dramatic improvement in operation was achieved in 1982-83 ;
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 62, 71 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 100, 109 ] }
if clinically significant embolization occurs during pta , this procedure can be attempted prior to surgical embolectomy as an alternative to local fibrinolytic therapy .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 64, 73 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 100, 108 ] }
preliminary findings indicate a correlation with such established techniques of evaluating erectile impotence as history , physical examination , penile pulse doppler tracings , and brachial-penile blood pressure index .
nichd_parent_of
{ "id": "C0220825", "name": "evaluating", "pos": [ 80, 90 ] }
{ "id": "C0031809", "name": "physical examination", "pos": [ 123, 143 ] }
of 95 consecutive patients with active variant angina who underwent ergonovine testing in the coronary care unit while off treatment , 24 ( 25 % ) developed serious ventricular arrhythmias : ventricular tachycardia in eight , bigeminy in seven , pairs in five , and frequent ventricular extrasystoles in four .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 165, 188 ] }
{ "id": "C0042514", "name": "ventricular tachycardia", "pos": [ 191, 214 ] }
two patients with recurrent unexplained syncope and no documented ventricular arrhythmia during electrocardiographic monitoring also had no inducible vt or vf .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmia", "pos": [ 66, 88 ] }
{ "id": "C0042514", "name": "vt", "pos": [ 150, 152 ] }
two patients with recurrent unexplained syncope and no documented ventricular arrhythmia during electrocardiographic monitoring also had no inducible vt or vf .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmia", "pos": [ 66, 88 ] }
{ "id": "C0042510", "name": "vf", "pos": [ 156, 158 ] }
to follow and predict the evolution of adiposity during growth , individual adiposity curves , assessed by the weight/height2 index , were drawn for 151 children from the age of 1 month to 16 yr .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 65, 75 ] }
{ "id": "C0008059", "name": "children", "pos": [ 153, 161 ] }
asplenic persons are at risk for the development of overwhelming sepsis from certain encapsulated bacteria , including meningococci .
nichd_parent_of
{ "id": "C0004611", "name": "bacteria", "pos": [ 98, 106 ] }
{ "id": "C0027575", "name": "meningococci", "pos": [ 119, 131 ] }
a giardia infected washington state child was found to participate in an infant and toddler swim class .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 36, 41 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 73, 79 ] }
a giardia infected washington state child was found to participate in an infant and toddler swim class .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 36, 41 ] }
{ "id": "C0682053", "name": "toddler", "pos": [ 84, 91 ] }
this paper details the normal anatomy of the area , and describes important modalities in evaluation of the retropharyngeal space , including physical exam , special x-ray procedures , and surgical approach .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 90, 100 ] }
{ "id": "C0031809", "name": "physical exam", "pos": [ 142, 155 ] }
a family study of psychiatric disorders in 2,003 first-degree relatives of 335 probands found increased rates of bipolar i disorder and major depression ( md ) in the relatives of probands with bipolar disorder and increased rates of md in the relatives of probands with md .
nichd_parent_of
{ "id": "C0004936", "name": "psychiatric disorders", "pos": [ 18, 39 ] }
{ "id": "C0005586", "name": "bipolar disorder", "pos": [ 194, 210 ] }
the patients were classified into 2 major groups : group i consisted of 24 patients with definite connective tissue disease -- 12 with scleroderma , including 8 with progressive systemic sclerosis ( pss ) , 6 with rheumatoid arthritis , 5 with systemic lupus erythematosus , and 1 with polymyositis ;
nichd_parent_of
{ "id": "C0011644", "name": "scleroderma", "pos": [ 135, 146 ] }
{ "id": "C0036421", "name": "progressive", "pos": [ 166, 177 ] }
the presence of ovarian hilar cells in fetuses and neonates whose mothers suffered from complications of pregnancy such as toxaemia of pregnancy , diabetes mellitus , accidental haemorrhage , hydrops foetalis and multiple pregnancy , has been investigated and compared with the presence of testicular leydig cells in sim...
nichd_parent_of
{ "id": "C0032962", "name": "complications of pregnancy", "pos": [ 88, 114 ] }
{ "id": "C0000832", "name": "accidental haemorrhage", "pos": [ 167, 189 ] }
the instrument provides for an accurate quantitative determination of blood microflow velocity , enables the measurements within a wide range of velocities and diameters of microvessels .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 40, 52 ] }
{ "id": "C1514721", "name": "range", "pos": [ 136, 141 ] }
the most striking finding was that s beta 2m gave an extremely reliable fit for survival prediction at ( 1 ) diagnosis , ( 2 ) remission , and ( 3 ) early relapse , with higher s beta 2m levels in each instance being in favor of poorer prognosis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 18, 25 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 109, 118 ] }
the results were consistent with other studies reporting associations between melanoma and poor tanning ability , a tendency to burn easily , and a history of sunburn and showed that light hair colour was the strongest risk factor for the disease .
nichd_parent_of
{ "id": "C0006434", "name": "burn", "pos": [ 128, 132 ] }
{ "id": "C0038814", "name": "sunburn", "pos": [ 159, 166 ] }
in a previously diagnosed lymphoma , aspiration aided in staging , in confirming recurrence , in the diagnosis of new and unrelated malignancy or undiagnosed infection and in assessing the evolution of a lymphoma to a more aggressive form .
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 132, 142 ] }
{ "id": "C0024299", "name": "lymphoma", "pos": [ 204, 212 ] }
a strong trend in this manner was also observed with tumors greater than or equal to 2 cm and types 3 and 5 scar cancers .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 53, 59 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 113, 120 ] }
forty-two percent of the patients achieved a complete response , and this included 50 % of patients with grade iii disease and 70 % of patients with a t1 tumor .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 115, 122 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 154, 159 ] }
only 2 of the 19 patients with low-grade tumors are known to have died of their disease and 9 of those whose tumor had spread beyond the ovary at the time of presentation were alive one or more years postoperatively .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 80, 87 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 109, 114 ] }
to characterize the frequency and severity of aberrations in energy expenditure in gi cancer patients , and to identify the potential influence of tumor characteristics in this group , the authors measured resting energy expenditure ( ree ) by indirect calorimetry in 173 patients and compared ree to predicted-energy ex...
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 153, 168 ] }
{ "id": "C0005910", "name": "body weight", "pos": [ 389, 400 ] }
correlation of serum tumor markers in advanced germ cell tumors with responses to chemotherapy and surgery .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 21, 26 ] }
{ "id": "C0205851", "name": "germ cell tumors", "pos": [ 47, 63 ] }
`` `` balanced '' '' translocations were noted in 10 children , of whom four had t ( 8 ; 21 ) associated with m2 anll , two had t ( 15 ; 17 ) and m3 anll , two had a t ( 9 ; 22 ) , one child with m5 anll had t ( 10p ; 11q ) , and an infant with congenital m5 anll had t ( 8 ; 16 ) .
nichd_parent_of
{ "id": "C0008059", "name": "e chi", "pos": [ 183, 188 ] }
{ "id": "C0021270", "name": "infa", "pos": [ 233, 237 ] }
levels of binding of dmba to dna and the distribution of individual dmba-deoxyribonucleoside adducts were similar in all cultures derived from fetuses of 13-15 days of gestation .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 57, 67 ] }
{ "id": "C0015965", "name": "fetuses", "pos": [ 143, 150 ] }
randomly chosen clones of the murine k-1735 melanoma tumor were used by raz and geiger to address the question of whether variations in actin organization in these cells may be related to their lung colonization capability in syngeneic hosts ( cancer res. , 42 : 5183-5190 , 1982 ) .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 53, 58 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 244, 250 ] }
the major tumors induced by the methoxy and methyl derivatives , both of which have high lipophilicity , were sarcomas ( fibrosarcomas and fibroanaplastic , anaplastic , and pleomorphic cell sarcomas ) in contrast to the fact that squamous cell carcinomas were the major tumors induced by mnu .
nichd_parent_of
{ "id": "C1261473", "name": "sarcomas", "pos": [ 110, 118 ] }
{ "id": "C0016057", "name": "fibrosarcomas", "pos": [ 121, 134 ] }
the results of experiments with various hypothalamic analogs in animal models of chondrosarcomas , osteosarcomas , and other tumors appear to be encouraging , but the potential clinical efficacy of lh-rh analogs in the treatment of human hormone-sensitive cancers other than breast and prostate remains to be investigate...
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 125, 131 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 256, 263 ] }
gram-negative organisms were frequent in the perioperative period and reflected either nosocomial infection or the ineffectiveness of the prophylactic antibiotic regimen used in inhibiting gram-negative pathogens .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 14, 23 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 203, 212 ] }
its analysis is important in understanding the pathogenesis of respiratory diseases and remains essential for the clinical diagnosis of most lung disorders .
nichd_parent_of
{ "id": "C0035204", "name": "respiratory diseases", "pos": [ 63, 83 ] }
{ "id": "C0024115", "name": "the", "pos": [ 110, 113 ] }
this longitudinal study has extended an earlier cross-sectional one in order to investigate the development of background activity and the topographical distribution of different eeg parameters during childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 201, 210 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 215, 226 ] }
because poa stimulation is known to initiate behavioral and electrocortical signs of sleep , it is suggested that `` '' fast units '' '' in sws with reduced discharge rates in w , may be `` '' hypnogenic '' '' cells .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 45, 55 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 85, 90 ] }
comparative study of the fluid-phase proteolytic cleavage of human complement subcomponents c4 and c2 by c1s and c1r2-c1s2 .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 25, 30 ] }
{ "id": "C0009516", "name": "complement", "pos": [ 67, 77 ] }
by extending the definition of pain into a psychogenic/organic dichotomy , the authors introduce the concept of personality variables and psychodynamic considerations that have been attributed to patients with chronic pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 31, 35 ] }
{ "id": "C0150055", "name": "chronic pain", "pos": [ 210, 222 ] }
histological examinations in all six patients revealed a typical est pattern , and in one of them another germ cell tumor , a malignant teratoma , was also found .
nichd_parent_of
{ "id": "C0027651", "name": "est", "pos": [ 65, 68 ] }
{ "id": "C0205851", "name": "germ cell tumor", "pos": [ 106, 121 ] }
complications included bacterial endocarditis in five patients ( three with aortic insufficiency and two with sepsis lenta ) , aortic insufficiency ( which was not of rheumatic or bacterial origin in three patients with conduction defects ) and thirteen patients with abnormalities of cardiac rhythm with small vsds .
nichd_parent_of
{ "id": "C0264886", "name": "conduction defects", "pos": [ 220, 238 ] }
{ "id": "C0003811", "name": "abnormalities", "pos": [ 268, 281 ] }
the recognition of this combined opportunistic fungal infection was brought about by an initial finding of birefringent calcium oxalate crystals associated with a background of acute inflammatory exudate , which is considered a strong clue to the diagnosis of infection caused by aspergillus niger .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 96, 103 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 247, 256 ] }
this finding also supports the hypothesis that the same variants tend to be transmitted and thereafter perpetuate within a family cluster .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 5, 12 ] }
{ "id": "C0242781", "name": "transmitted", "pos": [ 76, 87 ] }
the amlr has been shown to be impaired in several autoimmune disorders , such as systemic lupus erythematosus , sjogren 's syndrome , and primary biliary cirrhosis .
nichd_parent_of
{ "id": "C0004364", "name": "autoimmune disorders", "pos": [ 50, 70 ] }
{ "id": "C1527336", "name": "sjogren 's syndrome", "pos": [ 112, 131 ] }
sera from patients with other viral infections contained in most cases normal serum tk levels except in connection with measles , rubella , varicella , herpes simplex virus and cytomegalovirus infections .
nichd_parent_of
{ "id": "C0042769", "name": "viral infections", "pos": [ 30, 46 ] }
{ "id": "C0035920", "name": "rubella", "pos": [ 130, 137 ] }
the procedure of centrifugal elutriation was evaluated as a means of purifying large numbers of in situ lymphocytes from enzymatically disaggregated mouse mammary tumors .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 45, 54 ] }
this apparent constancy of the clinical picture reinforces the idea that aggressive conduct disorder is a valid , though broadly defined , psychiatric syndrome .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 92, 100 ] }
{ "id": "C0039082", "name": "syndrome", "pos": [ 151, 159 ] }
for other viruses , such as newcastle disease virus , semliki forest virus , encephalomyocarditis virus and poliovirus , treatment of cells with interferon also led to inhibition of viral protein synthesis .
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 10, 17 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 108, 118 ] }
the occurrence of these bodies in childhood crohn 's disease suggests that they may be disease-related , but their precise nature and relevance to this or other gastrointestinal disorders remain unknown .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 53, 60 ] }
{ "id": "C0017178", "name": "gastrointestinal disorders", "pos": [ 161, 187 ] }
the rr of cancers other than leukemia 10 years or more after intensive radiotherapy relative to no intensive therapy was 19.5 ( 95 % confidence limits : 4.8-80 ) .
nichd_parent_of
{ "id": "C0006826", "name": "cancers", "pos": [ 10, 17 ] }
{ "id": "C0023418", "name": "10", "pos": [ 38, 40 ] }
typical dose-effect responses were evident in urine of animals treated by all the administration routes tested ( i.p. , s.c. and per os ) , both in the presence and absence of a suspending vehicle .
nichd_parent_of
{ "id": "C0013153", "name": "administration", "pos": [ 82, 96 ] }
{ "id": "C1527415", "name": "per os", "pos": [ 129, 135 ] }
to test a possible antimutagenic activity of ethoxyquin ( eq ) in bone-marrow cells , 3 cytogenetic tests with distinct genetic end-points were applied .
nichd_parent_of
{ "id": "C0022885", "name": "test", "pos": [ 3, 7 ] }
{ "id": "C0679560", "name": "tests", "pos": [ 100, 105 ] }
the maori mortality rates were particularly high for the disease groupings of respiratory diseases , infectious diseases , genito-urinary diseases , endocrine , nutritional and metabolic disorders and diseases of the circulatory system other than coronary heart disease and cerebrovascular disease -- even when the data ...
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 57, 64 ] }
{ "id": "C0035204", "name": "respiratory diseases", "pos": [ 78, 98 ] }
the maori mortality rates were particularly high for the disease groupings of respiratory diseases , infectious diseases , genito-urinary diseases , endocrine , nutritional and metabolic disorders and diseases of the circulatory system other than coronary heart disease and cerebrovascular disease -- even when the data ...
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 57, 64 ] }
{ "id": "C0009450", "name": "infectious diseases", "pos": [ 101, 120 ] }
the results show that the boron-conjugated antibodies retain selective localization in the tumors , thus indicating their suitability for transporting boron-10 to tumors for use in neutron-capture therapy of cancer .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 91, 97 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 208, 214 ] }
using an objective scoring system , chest radiographs were reviewed in 23 cases of pneumonia due to the pittsburgh pneumonia agent ( ppa , tatlockia micdadei , legionella micdadei ) , including six cases of pneumonia with simultaneous isolation of ppa and l pneumophila ( legionnaires ' disease ) .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonia", "pos": [ 83, 92 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 272, 284 ] }
used as the initial procedure for evaluation of venous extension of hcc , ultrasound can suggest the histology ( though this must be confirmed by biopsy ) and determine the feasibility of resection .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 20, 29 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 34, 44 ] }
the disease is characterized by a deficiency in the cell-mediated immune system , which allows entrance to a host of opportunistic infections as well as tumors .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 4, 11 ] }
{ "id": "C0027651", "name": "tumors", "pos": [ 153, 159 ] }
a series of 244 renal biopsy specimens obtained from patients with glomerulonephritis included 21 from patients with membranous nephropathy ( mn ) .
nichd_parent_of
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 67, 85 ] }
{ "id": "C0017665", "name": "membranous nephropathy", "pos": [ 117, 139 ] }
a review of the clinical records of 25 patients with ivc thrombus , proved by cavography during a ten year period , showed that this form of venous thrombosis accounted for less than 5 per cent of all phlebographically documented dvt at this institution .
nichd_parent_of
{ "id": "C0042487", "name": "venous thrombosis", "pos": [ 141, 158 ] }
{ "id": "C0149871", "name": "dvt", "pos": [ 230, 233 ] }
multilobe disease at presentation was commoner in bacteraemic pneumococcal pneumonia ( 20/31 ) than in non-bacteraemic pneumococcal pneumonia ( 15/60 ) ( p less than 0.001 ) or legionnaires ' disease ( 19/49 ) ( p less than 0.025 ) .
nichd_parent_of
{ "id": "C0032285", "name": "pneumonia", "pos": [ 75, 84 ] }
{ "id": "C0023241", "name": "legionnaires", "pos": [ 177, 189 ] }
conversely , an index of animal food intake was inversely related to total stroke , significantly in hawaii , and at a suggestive level for total and hemorrhagic stroke in japan .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 75, 81 ] }
{ "id": "C0553692", "name": "hemorrhagic stroke", "pos": [ 150, 168 ] }
the mortality rates from stroke in rochester , minnesota , have declined 76 % since 1950 , and the primary cause for the declines is a decrease in the incidence of new cases of cerebral infarction and cerebral hemorrhage .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 25, 31 ] }
{ "id": "C2937358", "name": "cerebral hemorrhage", "pos": [ 201, 220 ] }