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in contrast , nonsteroidal antiinflammatory drugs ( nsaid ) and dietary essential fatty acid deficiency increase survival of rats subjected to endotoxin shock , and survival time in models of septic shock .
nichd_parent_of
{ "id": "C0036974", "name": "shock", "pos": [ 153, 158 ] }
{ "id": "C0036983", "name": "septic shock", "pos": [ 192, 204 ] }
a routine evaluation for the cause of her condition was positive only for certain physical factors .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 10, 20 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 82, 90 ] }
radionucleotide bone scanning can be an excellent adjunct to the standard radiograph and clinical findings in the diagnosis of osteomyelitis .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 89, 106 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 114, 123 ] }
the prevalence of thyroid and gastric antibodies , antinuclear and rheumatoid factors , in a probability based population sample .
nichd_parent_of
{ "id": "C0003241", "name": "antibodies", "pos": [ 38, 48 ] }
{ "id": "C0035448", "name": "rheumatoid factors", "pos": [ 67, 85 ] }
[ immunological studies on dna antibodies in lupus erythematosus ( sle , cdle ) , with particular reference to photo-oxidized dna ( podna ) antibody ] .
nichd_parent_of
{ "id": "C0409974", "name": "lupus erythematosus", "pos": [ 45, 64 ] }
{ "id": "C0024141", "name": "sle", "pos": [ 67, 70 ] }
[ evaluation of visual signs in preliminary and remote examinations of patients with extracerebral damage of the optic pathway ] .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 2, 12 ] }
{ "id": "C0031809", "name": "examinations of patients", "pos": [ 55, 79 ] }
comparison of the lymphocyte transformation test with the tuberculin test in rhesus monkeys and chimpanzees .
nichd_parent_of
{ "id": "C0022885", "name": "test", "pos": [ 44, 48 ] }
{ "id": "C0041290", "name": "tuberculin test", "pos": [ 58, 73 ] }
profound deficiency of a specific enzyme , galactocerebroside beta-galactosidase , has been demonstrated in the brains , liver , and spleen of three patients with krabbe 's globoid cell leucodystrophy .
nichd_parent_of
{ "id": "C0149676", "name": "deficiency of", "pos": [ 9, 22 ] }
{ "id": "C0023521", "name": "globoid cell leucodystrophy", "pos": [ 173, 200 ] }
[ chylous ascites in children . a case of an infant with hepatic and splenic enlargement and simultaneous cytomegalovirus infection ] .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 21, 29 ] }
{ "id": "C0021270", "name": "infant", "pos": [ 45, 51 ] }
[ posttraumatic osteoma of the patellar tendon in a patient suffering from osteogenesis imperfecta ( van der hoeve 's syndrome ] .
nichd_parent_of
{ "id": "C0029434", "name": "osteogenesis imperfecta", "pos": [ 75, 98 ] }
{ "id": "C0023931", "name": "van der hoeve 's syndrome", "pos": [ 101, 126 ] }
while epithelial tumours are multifocal and pass through well-defined intermediate stages ( radication , papillomas , microcarcinomas ) to full malignancy , the early stages of sarcoma formation are rarely detected and ill-defined .
nichd_parent_of
{ "id": "C0006826", "name": "malignancy", "pos": [ 144, 154 ] }
{ "id": "C1261473", "name": "sarcoma", "pos": [ 177, 184 ] }
pitfalls of functional tests for the establishment of the etiology of cushing 's syndrome in childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 93, 102 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 107, 118 ] }
a microscopic survey made to detect the presence of bacteria in hot springs of varying temperature and ph characteristics revealed that in neutral and alkaline hot springs bacteria are found at temperatures up to the boiling point of water ( 92 degrees to 100 degrees c , depending on the altitude ) .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 106, 121 ] }
{ "id": "C0039476", "name": "temperatures", "pos": [ 194, 206 ] }
[ the c.s.f . protein formula in central nervous system diseases and especially in multiple sclerosis . study of 218 examinations ] .
nichd_parent_of
{ "id": "C0007682", "name": "central nervous system diseases", "pos": [ 33, 64 ] }
{ "id": "C0026769", "name": "multiple sclerosis", "pos": [ 83, 101 ] }
to study the extent of the hazard presented by oysters contaminated with virus , samples of whole and shucked pacific oysters contaminated with 10 ( 4 ) pfu of poliovirus lsc-2ab per ml were heat processed in four ways : by stewing , frying , baking , and steaming .
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 73, 78 ] }
{ "id": "C0206435", "name": "poliovirus", "pos": [ 160, 170 ] }
malignant tumors involving bone of nonosseous origin ( myeloma , malignant lymphoma , ewing 's sarcoma , chordoma , adamantinoma , angiosarcoma , liposarcoma ) .
nichd_parent_of
{ "id": "C0006826", "name": "malignant tumors", "pos": [ 0, 16 ] }
{ "id": "C0024299", "name": "malignant", "pos": [ 65, 74 ] }
it provides quantitative measurement in the range 2.5-10 who iu/ml and semi-quantitative measurement up to 30 who iu/ml , without the need for serial dilution .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 12, 24 ] }
{ "id": "C1514721", "name": "range", "pos": [ 44, 49 ] }
we describe the cases of four children with aplastic crises in various types of thalassaemia ( alpha and beta thalassaemias , major and intermediate forms ) .
nichd_parent_of
{ "id": "C0039730", "name": "thalassaemia", "pos": [ 80, 92 ] }
{ "id": "C0005283", "name": "beta thalassaemias", "pos": [ 105, 123 ] }
the adjusted incidence rate for bacterial meningitis was 8.6/100,000 person-years ( with a case fatality ratio of 10 % ) and was highest in children less than five years of age ;
nichd_parent_of
{ "id": "C0027361", "name": "person", "pos": [ 69, 75 ] }
{ "id": "C0008059", "name": "children", "pos": [ 140, 148 ] }
all the subjects were evaluated by digital palpatory physical examination for the presence of trigger points before each of their treatments .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 22, 31 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 53, 61 ] }
this procedure offers a simple , inexpensive and very sensitive technique for evaluating fibronectin : reproducible standard curves in the range 5-100 micrograms/l , 3 % variability in the assay , and a detection limit of 0.5 ng/well that allows accurate measurement of fibronectin in segmental bronchoalveolar lavage an...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0220825", "name": "evaluating", "pos": [ 78, 88 ] }
parallel assays of ldl cholesterol according to the new method and using quantitative lipoprotein electrophoresis as reference showed the results , in terms of the individual values and collectively , to be practically identical for a wide concentration range of various lipids and lipoproteins in the serum .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 73, 85 ] }
{ "id": "C1514721", "name": "range", "pos": [ 254, 259 ] }
here we report that such infections result in unique and selective changes in the normal levels of cns neurotransmitters some of which persist after infectious virus can no longer be detected .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 25, 35 ] }
{ "id": "C0042769", "name": "infectious virus", "pos": [ 149, 165 ] }
when the number of malignancies in these rats was compared with control and sham-operated animals , a small increase in sarcomata was observed in animals bearing metal alloy implants containing high contents of cobalt , chromium , or nickel .
nichd_parent_of
{ "id": "C0006826", "name": "malignancies", "pos": [ 19, 31 ] }
{ "id": "C1261473", "name": "sarcomata", "pos": [ 120, 129 ] }
these differences suggest a disturbance of autonomic function prior to death in some victims of sids .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 71, 76 ] }
{ "id": "C0038644", "name": "death", "pos": [ 71, 76 ] }
these measurements may more accurately assess intrauterine growth and body proportionality at birth than weight , length , and head circumference .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 114, 120 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 127, 145 ] }
these women appeared to have had more complaints during their pregnancy and menstrual periods , more complications in their obstetrical history and to be more anxious about their labour than women who chose a spontaneous onset of labour .
nichd_parent_of
{ "id": "C0022864", "name": "labour", "pos": [ 179, 185 ] }
{ "id": "C0474461", "name": "spontaneous onset of labour", "pos": [ 209, 236 ] }
all 4 measurements showed significant differences between controls , raynaud 's phenomenon and systemic sclerosis but only capillaroscopy ( mean number of enlarged capillary loops and avascular score ) was able to differentiate between primary raynauds and undifferentiated connective tissue disease .
nichd_parent_of
{ "id": "C0034735", "name": "raynaud 's phenomenon", "pos": [ 69, 90 ] }
{ "id": "C0151445", "name": "primary raynauds", "pos": [ 236, 252 ] }
this evaluation included a review of the school health records , a medical history , physical examination , and a parent-completed questionnaire assessing their child 's behaviour and social competence .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 5, 15 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 85, 93 ] }
the implications of these findings for family intervention and support programmes are considered , together with the need for research into the various ecological contexts of the individual , family , peer group and social institutions , as well as of the interactions within and between these contexts as mediators of c...
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 179, 189 ] }
{ "id": "C0008059", "name": "children", "pos": [ 380, 388 ] }
as the disease progressed , evidence of remyelination and ongoing demyelination was observed up to 65 days after infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 7, 14 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 113, 122 ] }
we describe a new procedure in which dorsal penile skin is used to correct hypospadias in circumcised patients and those in whom surgical correction usually is difficult .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 18, 27 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 129, 137 ] }
we have evaluated the effects of physical and several chemical fixatives on prostate samples obtained immediately after prostatectomies and radical cystectomies .
nichd_parent_of
{ "id": "C0220825", "name": "evaluated", "pos": [ 8, 17 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 33, 41 ] }
intestinal trichostrongyloidosis ( four of 55 ; 7 % ) , purulent bronchopneumonia ( three of 55 ; 5 % ) and septicemia ( three of 55 ; 5 % ) were the major disease syndromes seen in free-living echidnas .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 156, 163 ] }
{ "id": "C0039082", "name": "syndromes", "pos": [ 164, 173 ] }
we developed a computerized infectious disease monitor that automatically generates four types of surveillance `` '' alerts '' '' for patients with hospital-acquired infections , not receiving antibiotics to which their pathogens are susceptible , who could be receiving less expensive antibiotics , or who are receiving...
nichd_parent_of
{ "id": "C0009450", "name": "infectious disease", "pos": [ 28, 46 ] }
{ "id": "C0205721", "name": "hospital-acquired infectio", "pos": [ 148, 174 ] }
the underlying respiratory diseases included chronic pulmonary emphysema in 6 subjects , diffuse panbronchiolitis in 3 , bronchiectasis in 3 , silicosis in 2 and one each of chronic bronchitis , pulmonary fibrosis , lung cancer and old pulmonary tuberculosis .
nichd_parent_of
{ "id": "C0035204", "name": "respiratory diseases", "pos": [ 15, 35 ] }
{ "id": "C0034069", "name": "pulmonary fibrosis", "pos": [ 195, 213 ] }
the incidence of infections was low , and no serious bacterial infection occurred in these 33 patients .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 17, 27 ] }
{ "id": "C0004623", "name": "bacterial infection", "pos": [ 53, 72 ] }
to determine whether this phenomenon occurs also in vivo , 244 routine paraffin-embedded tumors including 32 sclc and 79 non-sclc ( nsclc ) lung cancers were studied for expression of beta 2-microglobulin ( beta 2m ) by an avidin-biotin coupled immunoperoxidase technique .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 89, 95 ] }
{ "id": "C0006826", "name": "sclc", "pos": [ 133, 137 ] }
the tumor factor ( s ) responsible for this lipolysis-promoting activity may account for the fat wasting that often accompanies malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 4, 9 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 128, 138 ] }
the suppressive moiety from one tumor had an apparent mass of 45 kda by gel filtration chromatography , in contrast to murine tdsf that has a mass of more than 300 kda .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 32, 37 ] }
{ "id": "C0577559", "name": "a mass", "pos": [ 140, 146 ] }
because dr4 is associated with rheumatoid arthritis ( ra ) and because a role for m tuberculosis antigens has been suggested both in experimentally induced autoimmune arthritis in rats and in ra , the dr4 associated regulation of the immune response to m tuberculosis may be relevant to the pathogenesis of ra .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 42, 51 ] }
{ "id": "C0003873", "name": "ra", "pos": [ 307, 309 ] }
on thirty-one tests carried out monthly for 7 months in seventeen patients with rheumatoid arthritis , the consensus analysis procedure ranked plasma viscosity and erythrocyte sedimentation rate in a tie for first place .
nichd_parent_of
{ "id": "C0022885", "name": "tests", "pos": [ 14, 19 ] }
{ "id": "C1176468", "name": "erythrocyte sedimentation rate", "pos": [ 164, 194 ] }
it is noteworthy that there is a significant correlation in spite of large differences in background subjects ( systemic condition , size of metastatic lesion , etc . ) and the growth rate of tumor is considered to play a very important role for determining the degree of biological malignancy of individual cancer patie...
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 192, 197 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 308, 314 ] }
in eight patients with thoracic diabetic radiculopathy at the level of t7-t12 , awms was abnormal in all and was considered to be diagnostic , whereas awms was normal in diabetic lumbar radiculopathy , patients with diabetes mellitus without radiculopathy , patients with unspecified gastrointestinal pain , and patients...
nichd_parent_of
{ "id": "C0030193", "name": "unspecified", "pos": [ 272, 283 ] }
{ "id": "C0004604", "name": "back pain", "pos": [ 347, 356 ] }
we recommend cytogenetic screening for the fragile x syndrome in all currently identified intellectually handicapped people , followed by routine screening of children newly identified as intellectually handicapped in the school system .
nichd_parent_of
{ "id": "C0027361", "name": "people", "pos": [ 117, 123 ] }
{ "id": "C0008059", "name": "children", "pos": [ 159, 167 ] }
complete occlusion of the infarct-related coronary artery is a frequent finding soon after q-wave ( transmural ) myocardial infarction .
nichd_parent_of
{ "id": "C0021308", "name": "infarct", "pos": [ 26, 33 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 113, 134 ] }
these data suggest that neurohypophysial nerve terminals prepared by a collagenase dispersion procedure may be suitable for the investigation of posterior pituitary secretion mechanisms .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 94, 103 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 128, 141 ] }
however , despite reports of occasional unexpectedly favorable outcome in surgically treated patients , these injuries have been viewed pessimistically and indeed have generally been excluded from modern studies of head injuries , which have concentrated on closed head injuries .
nichd_parent_of
{ "id": "C3263723", "name": "injuries", "pos": [ 110, 118 ] }
{ "id": "C0018674", "name": "of", "pos": [ 212, 214 ] }
babies were later separated into those without intracranial hemorrhage , those who had only subependymal hemorrhage ( seh ) , and those with intraventricular/intracerebral hemorrhage .
nichd_parent_of
{ "id": "C0151699", "name": "intracranial", "pos": [ 47, 59 ] }
{ "id": "C0240059", "name": "intraventricular/intracerebral hemorrhage", "pos": [ 141, 182 ] }
in three cases of medium-sized avm , the procedure was followed by a total excision of the lesion during the same operation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 41, 50 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 114, 123 ] }
the organisms isolated were those commonly found in other types of pelvic infection : pathogenic aerobes and anaerobes as well as commensals .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 4, 13 ] }
{ "id": "C0450254", "name": "pathogenic", "pos": [ 86, 96 ] }
in soft issue tumors , the following should be taken into consideration : malignant synovialoma , fibrosarcoma , hemangioma , lipoma , giant cell tumors , and fibromatosis .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 14, 20 ] }
{ "id": "C0018916", "name": "hemangioma", "pos": [ 113, 123 ] }
in soft issue tumors , the following should be taken into consideration : malignant synovialoma , fibrosarcoma , hemangioma , lipoma , giant cell tumors , and fibromatosis .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 14, 20 ] }
{ "id": "C0023798", "name": "lipoma", "pos": [ 126, 132 ] }
for all physicians , the diagnostic utility of pain descriptors was rated higher for acute than for chronic pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 47, 51 ] }
{ "id": "C0150055", "name": "chronic pain", "pos": [ 100, 112 ] }
the i-sm had significantly reduced birth weight , length , and head circumference but there was no difference in skinfold thickness .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 50, 56 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 63, 81 ] }
in normal weight children the activity was also found in the majority of infants , but was infrequent in older children .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 17, 25 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 73, 80 ] }
in individual children , tetanus-specific subclass responses were similar in pattern to that for total igg tetanus antibody , i.e . each igg subclass response appeared to be regulated by similar mechanisms in that child , but the regulation differed between children .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 3, 13 ] }
{ "id": "C0008059", "name": "children", "pos": [ 258, 266 ] }
two subsequent children were detected by newborn thyroid screen to have low thyroxine and markedly elevated serum thyrotropin ( tsh ) levels .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 15, 23 ] }
{ "id": "C0021289", "name": "newborn", "pos": [ 41, 48 ] }
oesophageal motor function was studied by oesophageal manometry in 48 patients with progressive systemic sclerosis : 25 with proximal scleroderma and 23 with diffuse scleroderma .
nichd_parent_of
{ "id": "C0011644", "name": "scleroderma", "pos": [ 134, 145 ] }
{ "id": "C0036421", "name": "diffuse scleroderma", "pos": [ 158, 177 ] }
these results are discussed within the context of the hypoxic state of many solid tumors and the high frequency of aneuploidy , chromosomal aberrations , and spontaneously occurring resistances to a number of cancer chemotherapeutic agents .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 82, 88 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 209, 215 ] }
the effects of diltiazem on ventricular arrhythmias and ventricular vulnerability for fibrillation , both in the very beginning of myocardial ischemia and in the early stage of myocardial necrosis , were evaluated in 13 mongrel dogs .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 28, 51 ] }
{ "id": "C0042510", "name": "ventricular", "pos": [ 56, 67 ] }
comparison of this procedure with an alternative , but irreversible , spinal preparation ( chemomyelotomy ) indicates that reversible lidocaine anesthesia does not differentially influence the activity of rat fetuses on day 19 of gestation .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 19, 28 ] }
{ "id": "C0002903", "name": "anesthesia", "pos": [ 144, 154 ] }
behavioral and electrographic observations confirmed the existence of well defined sleep states : slow-wave sleep ( sws ) and paradoxical sleep ( ps ) .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 0, 10 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 138, 143 ] }
during the second psychotic episode she developed ictal vegetative phenomena such as profuse sweating , flush , apnoea , and , above all and most alarming , periods of severe bradycardia and asystolia with clinical signs of syncope .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 206, 220 ] }
{ "id": "C0039070", "name": "syncope", "pos": [ 224, 231 ] }
in that study , we noted that in several instances malignant mesothelioma ( either intrathoracic or unspecified site ) was listed on the death certificate in such a manner as to imply that the neoplasm was either a lung cancer or a malignancy of an unspecified site .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasm", "pos": [ 193, 201 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 232, 242 ] }
in one case the procedure was performed to dislodge the foreign body into a better position for surgical retrieval .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 16, 25 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 96, 104 ] }
the authors investigated 55 determinations of synovial lactic acid in 7 groups of patients : septic arthritis , seropositive rheumatoid arthritis , seronegative rheumatoid arthritis , psoriatic arthritis , ankylosing spondylitic arthritis , reactive arthritis , mechanical fluids of osteoarthritis .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 100, 109 ] }
{ "id": "C0085435", "name": "reactive arthritis", "pos": [ 241, 259 ] }
the cardiac silhouette was radiographically enlarged in all cases , but this finding was seldom diagnostic .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 77, 84 ] }
{ "id": "C0011900", "name": "diagnostic", "pos": [ 96, 106 ] }
labour was induced in 32 high-risk twin pregnancies and the outcome compared with that in 32 twin pregnancies ending in spontaneous labour .
nichd_parent_of
{ "id": "C0022864", "name": "labour", "pos": [ 0, 6 ] }
{ "id": "C0474461", "name": "spontaneous labour", "pos": [ 120, 138 ] }
portal disconnection of the esophagus using an anastomotic button is a simple and effective procedure which can benefit many patients with cirrhosis who undergo an operation for bleeding varices on an elective or emergency basis .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 92, 101 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 164, 173 ] }
by results obtained it is put up for discussion to replace `` '' five-years-rate '' '' by `` '' three-years-rate '' '' in cases of gynecological malignancies with exception of mammary carcinoma .
nichd_parent_of
{ "id": "C0006826", "name": "cal malignan", "pos": [ 141, 153 ] }
{ "id": "C0678222", "name": "of mammary carci", "pos": [ 173, 189 ] }
cytomegalovirus ( cmv ) infections occur worldwide and are responsible for severe damage to the child in from one to five newborns per 20,000 births .
nichd_parent_of
{ "id": "C0008059", "name": "child", "pos": [ 96, 101 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 122, 130 ] }
development of procedures for the culture of rat embryos with hepatocytes from other species suggests the utility of this in vitro system for the investigation of species differences in sensitivity to chemical teratogens .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 15, 25 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 146, 159 ] }
in twelve percent of the cases stroke was caused by subarachnoid hemorrhage and in ten percent by cerebral hemorrhage .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 31, 37 ] }
{ "id": "C2937358", "name": "cerebral hemorrhage", "pos": [ 98, 117 ] }
in 15 per cent of the prevalence cases the stroke was caused by subarachnoid hemorrhage , in six per cent by cerebral hemorrhage and in the remainder by cerebral infarction or the type could not be specified .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 43, 49 ] }
{ "id": "C2937358", "name": "cerebral", "pos": [ 153, 161 ] }
eight patients ( 16 % ) suffered a stroke during follow-up , of which five were within the vascular territory of the occluded artery -- 5 patients ( 10 % ) developed tias 4 of which were ipsilateral to the occluded artery .
nichd_parent_of
{ "id": "C0038454", "name": "stroke", "pos": [ 35, 41 ] }
{ "id": "C0007787", "name": "tias", "pos": [ 166, 170 ] }
in an effort to overcome these problems we have devised a method of diverting thoracic duct lymph internally into the esophagus of the sheep , our hypothesis being that fluid and protein should be resorbed , but lymphocytes and antibodies destroyed .
nichd_parent_of
{ "id": "C0005889", "name": "fluid", "pos": [ 169, 174 ] }
{ "id": "C0003241", "name": "antibodies", "pos": [ 228, 238 ] }
after injection of cba cells , the characteristic increases in crypt length , crypt cell production rate ( ccpr ) , and intraepithelial lymphocyte ( iel ) count occurred in the jejunum of ( cba x balb/c ) f1 -- -- cba bm chimeras , but not in cba -- -- ( cba x balb/c ) f1 bm chimeras .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 35, 49 ] }
{ "id": "C1444754", "name": "length", "pos": [ 69, 75 ] }
the human il-1 family plays an important role in the pathogenesis of many diseases and functions as a key mediator of host response to various infectious , inflammatory , neoplastic , and immunologic challenges .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 74, 82 ] }
{ "id": "C0009450", "name": "infectious", "pos": [ 143, 153 ] }
these data indicate an early and fairly distinctive involvement of the nervous system in syphilis and the necessity of a wider use of non-invasive methods of examination for diagnosing latent and subclinical forms of neurosyphilis in conditions of dermatovenerological and neurological clinics .
nichd_parent_of
{ "id": "C0039128", "name": "syphilis", "pos": [ 89, 97 ] }
{ "id": "C0027927", "name": "neurosyphilis", "pos": [ 217, 230 ] }
the pathoanatomical characteristics of hemorrhages and infarcts of the hypophysis is given , the pathogenesis of these disorders is discussed , and the leading role of mechanical factors in the development of disorders of blood circulation is pointed out .
nichd_parent_of
{ "id": "C0012634", "name": "disorders", "pos": [ 119, 128 ] }
{ "id": "C0018939", "name": "the", "pos": [ 190, 193 ] }
the scleroderma ( literally , hard skin ) , or progressive systemic sclerosis ( pss ) , is a multisystem disease and can present various anaesthetic problems .
nichd_parent_of
{ "id": "C0011644", "name": "scleroderma", "pos": [ 4, 15 ] }
{ "id": "C0036421", "name": "progressive systemic sclerosis", "pos": [ 47, 77 ] }
those with pregnancy complications ( hypertension , premature labor and fetal growth retardation ) appeared to have significantly abnormal venous reactivity .
nichd_parent_of
{ "id": "C0032962", "name": "pregnancy complications", "pos": [ 11, 34 ] }
{ "id": "C0022876", "name": "premature labor", "pos": [ 52, 67 ] }
in 8 evaluated cases with clinical acute graft versus host disease ( gvhd ) , involvement of acute gvhd was histologically confirmed in the skin , liver , and/or intestine .
nichd_parent_of
{ "id": "C0018133", "name": "gvhd", "pos": [ 69, 73 ] }
{ "id": "C0856825", "name": "acute", "pos": [ 93, 98 ] }
among 10 cases ( 3 , acute myelocytic leukemia ; 4 , acute myelomonocytic leukemia ; 2 , acute monocytic leukemia ; and one , acute erythroleukemia ) in which an evaluation was possible , 5 cases ( 3 , acute myelomonocytic leukemia ; and 2 , acute monocytic leukemia ) obtained complete remission ( cr ) .
nichd_parent_of
{ "id": "C0023467", "name": "acute myelocytic leukemia", "pos": [ 21, 46 ] }
{ "id": "C0023479", "name": "acute myelomonocytic leukemia", "pos": [ 202, 231 ] }
the results suggest that acr is effective for the clinical management of elderly patients with acute nonlymphocytic leukemia , especially those with acute myelomonocytic leukemia or acute monocytic leukemia .
nichd_parent_of
{ "id": "C0023467", "name": "acute nonlymphocytic leukemia", "pos": [ 95, 124 ] }
{ "id": "C0023479", "name": "acute myelomonocytic leukemia", "pos": [ 149, 178 ] }
when these biologic factors are fully evaluated , it should be possible to predict the response to be expected from vaccination at any particular age without directly testing the vaccine in children below and above generally recommended ages for vaccination .
nichd_parent_of
{ "id": "C0005515", "name": "biologic factors", "pos": [ 11, 27 ] }
{ "id": "C0042210", "name": "vaccine", "pos": [ 179, 186 ] }
major infections after the period of initial engraftment include viral infections ( especially cytomegalovirus ) , fungal infections ( due to aspergillus and candida ) , and rarely protozoal infections .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 6, 16 ] }
{ "id": "C0042769", "name": "viral infections", "pos": [ 65, 81 ] }
major infections after the period of initial engraftment include viral infections ( especially cytomegalovirus ) , fungal infections ( due to aspergillus and candida ) , and rarely protozoal infections .
nichd_parent_of
{ "id": "C3714514", "name": "infections", "pos": [ 6, 16 ] }
{ "id": "C0026946", "name": "fungal infections", "pos": [ 115, 132 ] }
less common types of infection include suppurative thrombophlebitis , suppurative chondritis , bacterial endocarditis , urinary tract sepsis , sinusitis , intra-abdominal sepsis , and infections of the eyes .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 21, 30 ] }
{ "id": "C0037199", "name": "sinusitis", "pos": [ 143, 152 ] }
diagnosis of these infections can be complicated by underlying disease , surgery , or the prosthesis itself , making it difficult to ascertain whether abnormalities of routine diagnostic studies are caused by infection .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 63, 70 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 209, 218 ] }
the frequent isolation of skin organisms ( such as staphylococcus epidermidis ) as the pathogen can also cause confusion as to whether the culture was contaminated .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 31, 40 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 87, 95 ] }
also at risk are heterosexual partners of persons who have overt acquired immunodeficiency syndrome or who are at risk for acquired immunodeficiency syndrome , as are children born to mothers who either have acquired immunodeficiency syndrome or are members of a `` '' high-risk group . '' ''
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 42, 49 ] }
{ "id": "C0008059", "name": "children", "pos": [ 167, 175 ] }
on the other hand , features following general body growth , such as height , weight ( represented here by vertebral body height ) continues to grow until young adulthood .
nichd_parent_of
{ "id": "C1521970", "name": "features", "pos": [ 20, 28 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 78, 84 ] }
the data were used in a three-tiered validation procedure to evaluate 14 competing forms of elastance [ e ( t ) ] -resistance ( r ) left ventricle ( lv ) pump models .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 48, 57 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 61, 69 ] }
to determine the efficacy of evaluating persons ( associates ) in close contact to children with significant tuberculin reactions , we prospectively evaluated 831 associates of 297 children younger than eight years who had significant ( greater than or equal to 10 mm ) tuberculin reactions .
nichd_parent_of
{ "id": "C0027361", "name": "persons", "pos": [ 40, 47 ] }
{ "id": "C0008059", "name": "children", "pos": [ 181, 189 ] }
the development of significant dysrhythmias ( frequent premature ventricular contractions , ventricular tachycardia , bradycardia , second- and third-degree heart blocks ) after initiation into the study was similar in both groups of patients .
nichd_parent_of
{ "id": "C0003811", "name": "dysrhythmias", "pos": [ 31, 43 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 118, 129 ] }
the development of significant dysrhythmias ( frequent premature ventricular contractions , ventricular tachycardia , bradycardia , second- and third-degree heart blocks ) after initiation into the study was similar in both groups of patients .
nichd_parent_of
{ "id": "C0003811", "name": "dysrhythmias", "pos": [ 31, 43 ] }
{ "id": "C0151517", "name": "third-degree heart blocks", "pos": [ 144, 169 ] }
however , calves did not develop clinical signs of respiratory tract disease before euthanasia or death .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 33, 47 ] }
{ "id": "C0011065", "name": "death", "pos": [ 98, 103 ] }
the synergistic hemolysis-inhibition ( shi ) test , a serologic test for the detection of infection with corynebacterium pseudotuberculosis , was applied to serum samples from 196 goats and 76 sheep , including animals both with and without c pseudotuberculosis abscesses .
nichd_parent_of
{ "id": "C0009450", "name": "infection", "pos": [ 90, 99 ] }
{ "id": "C0000833", "name": "abscesses", "pos": [ 262, 271 ] }