text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
conjugation was favoured on dry absorbent surfaces , e.g. , human skin , tissue and surgical gauze , whereas phage-mediated conjugation was favoured in fluids , e.g. , milk and urine . | nichd_parent_of | {
"id": "C0005889",
"name": "fluids",
"pos": [
152,
158
]
} | {
"id": "C0026131",
"name": "milk",
"pos": [
168,
172
]
} |
two distinct processes appear to have occurred : in infants who experienced patent ductus arteriosus or intracranial hemorrhage ( conditions associated with hypoxia ) where tpn may be the necessary trigger for the development of cholestasis , and in infants with gastrointestinal conditions requiring surgery or sepsis ,... | nichd_parent_of | {
"id": "C0017178",
"name": "gastrointestinal conditions",
"pos": [
263,
290
]
} | {
"id": "C0008370",
"name": "cholestasis",
"pos": [
327,
338
]
} |
at the time of admission , besides anemia , jaundice and a tendency to bleeding , the laboratory data showed , hyperbilirubinemia , elevated fdp and hemolytic anemia with fragmented red cells . | nichd_parent_of | {
"id": "C0002871",
"name": "anemia",
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35,
41
]
} | {
"id": "C0002878",
"name": "hemolytic anemia",
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165
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} |
syncytiotrophoblastic tumor cells were seen sporadically in the cancer nest , and they showed diffuse positive staining for hcg by immunohistochemical techniques . | nichd_parent_of | {
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"name": "tumor",
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22,
27
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} | {
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"name": "cancer",
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gonadal function was followed in 26 females and 12 males with galactosaemia due to deficiency of the enzyme galactose-1-phosphate ( gal-1-p ) uridyl transferase over a 4 year period . | nichd_parent_of | {
"id": "C0016952",
"name": "galactosaemia",
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62,
75
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} | {
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it requires that literature models for the role of the protonmotive force in the maintenance of wall thickness in gram-positive organisms , the adhesion of microbes to surfaces , and the transport of auxin in plants be modified . | nichd_parent_of | {
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} | {
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156,
164
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normalization of granulocyte counts was obtained with low-dose cytosine arabinoside ( ara-c ) in a patient with acute myelogenous leukemia ( aml , fab-m2 ) who had relapsed on maintenance therapy containing conventional doses of ara-c and was clinically resistant to high-dose ara-c treatment . | nichd_parent_of | {
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144
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} | {
"id": "C1879321",
"name": "fab-m2",
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147,
153
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} |
it was used for diverse hyperkeratotic skin conditions ( psoriasis , xerosis , pityriasis rubra pilaris , stuccokeratosis , seborrheic dermatitis , stasis dermatitis , pityriasis lichenoides chronica ) . | nichd_parent_of | {
"id": "C0037274",
"name": "skin conditions",
"pos": [
39,
54
]
} | {
"id": "C0033860",
"name": "psoriasis",
"pos": [
57,
66
]
} |
it was used for diverse hyperkeratotic skin conditions ( psoriasis , xerosis , pityriasis rubra pilaris , stuccokeratosis , seborrheic dermatitis , stasis dermatitis , pityriasis lichenoides chronica ) . | nichd_parent_of | {
"id": "C0037274",
"name": "skin conditions",
"pos": [
39,
54
]
} | {
"id": "C0036508",
"name": "seborrheic",
"pos": [
124,
134
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} |
a model is proposed to explain basic features of viral oncogenesis in man such as the long interval between primary infection and tumour appearance , the small number of infected individuals in whom cancer develops , and the monoclonality of the tumours . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
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136
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} | {
"id": "C0006826",
"name": "cancer",
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199,
205
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} |
proceeding from the results of the comprehensive radionuclide study and the clinical findings the diagnosis of hepatic hemangioma was established . | nichd_parent_of | {
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"name": "clinical findings",
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93
]
} | {
"id": "C0011900",
"name": "diagnosis",
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} |
the difference in risk between most clinical manifestations of analgesic nephropathy and death ( or end-stage renal disease ) may be due to the fact that most patients with nephropathy do not progress to terminal renal failure . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
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84
]
} | {
"id": "C0022661",
"name": "terminal renal failure",
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226
]
} |
when patients have unlocalizable or unresectable foci , depending on their exact pattern of seizures , electrical abnormalities , and neurologic status , other procedures may be used for surgical control of seizures . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
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170
]
} | {
"id": "C0543467",
"name": "surgical",
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} |
because of the multiplicity of the tumors and the association with tuberous sclerosis we presumed that the tumors were rhabdomyomas . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
35,
41
]
} | {
"id": "C0035411",
"name": "rhabdomyomas",
"pos": [
119,
131
]
} |
as it is known that rhabdomyomas show no , or only a minimal postnatal growth , we decided neither to perform a heart catheterization nor to treat them surgically unless the children show hemodynamical deterioration , although the tumors were huge in both neonates . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
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182
]
} | {
"id": "C0021289",
"name": "neonates",
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256,
264
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} |
a simple haematoxylin and eosin staining procedure was evaluated in the micronucleus test using rats and mice . | nichd_parent_of | {
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41,
50
]
} | {
"id": "C0220825",
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} |
therefore , this staining procedure may offer a useful alternative , for example , when evaluating rat bone-marrow smears within which considerable mast cell contamination can occur . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
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} | {
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} |
while this test , like all others , has some limitations , it is recommended that it be regularly included in all genetic testing batteries . | nichd_parent_of | {
"id": "C0022885",
"name": "test",
"pos": [
11,
15
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} | {
"id": "C0679560",
"name": "genetic",
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} |
thirty-six patients had strokes or transient ischemic attacks , 51 had cardiac ischemic events , and 45 died . | nichd_parent_of | {
"id": "C0038454",
"name": "strokes",
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24,
31
]
} | {
"id": "C0007787",
"name": "transient ischemic attacks",
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35,
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} |
the overall incidence of stroke at one year was 1.7 percent ( 1 percent in patients without previous transient ischemic attacks ) , but the incidence was 5.5 percent in patients with severe carotid-artery stenosis ( greater than 75 percent ) . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
25,
31
]
} | {
"id": "C0007787",
"name": "transient",
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101,
110
]
} |
[ the value of rapid diagnosis of sexually transmissible diseases , specifically of gonorrhea , chlamydia trachomatis infections and herpes genitalis ] . | nichd_parent_of | {
"id": "C0036916",
"name": "sexually transmissible diseases",
"pos": [
34,
65
]
} | {
"id": "C0018081",
"name": "gonorrhea",
"pos": [
84,
93
]
} |
this binding procedure could prove useful in the evaluation of oestrogen responsivity under normal and pathological conditions . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
13,
22
]
} | {
"id": "C0220825",
"name": "evaluation",
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49,
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]
} |
using the enzyme-linked immunosorbent assay ( elisa ) , we detected antibodies to interstitial ( type i ) and basement membrane ( type iv ) collagens in the sera of patients with scleroderma ( systemic sclerosis ) . | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
"pos": [
179,
190
]
} | {
"id": "C0036421",
"name": "systemic sclerosis",
"pos": [
193,
211
]
} |
endurance fitness has been measured objectively ( physical work capacity at pulse rate of 170/min w170 ) in a group of middle-aged executives , and related to a number of other physical characteristics and aspects of coronary risk status : fev1 , blood pressure , adiposity smoking habit , alcohol consumption , plasma l... | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
186,
201
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} | {
"id": "C0005823",
"name": "blood pressure",
"pos": [
247,
261
]
} |
the value of two dimensional echocardiography in identifying communications between the ascending aorta and pulmonary trunk or individual pulmonary arteries was assessed in 24 children , all of whom had either angiocardiographic and surgical or angiocardiographic confirmation alone . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
127,
137
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
176,
184
]
} |
the study shows that the usual effects of training are observed in patients on beta blockers , and that heart rate remains a useful guide to their evaluation throughout a physical training programme . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluation",
"pos": [
147,
157
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
171,
179
]
} |
an important characteristic of these length-tension curves is that normalized lengths correspond to the same absolute length in each group of vessels when the reference length has the same absolute value ( l0 and lmin in this study ) . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
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13,
27
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
169,
175
]
} |
in 35 ( 94.6 % ) of 36 malignant tumors ( anaplastic carcinoma , six ; papillary carcinoma 23 ; follicular carcinoma , five ; epidermoid carcinoma , one ; malignant lymphoma , 1 ) 201ti accumulated in the cold nodule of the 123i thyroid scan on both early and delayed scans . | nichd_parent_of | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
23,
39
]
} | {
"id": "C0024299",
"name": "malignant lymphoma",
"pos": [
155,
173
]
} |
phase ii study of amsa in patients with metastatic breast cancer : a cancer and leukemia group b study . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
58,
64
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
89,
94
]
} |
postcatheterization testing identified ranges of volume and flow-rate characteristics which included 8 ml at 15 ml/sec ( 40 cm length ) , at 11 ml/sec ( 50 cm length ) , and at 9 ml/sec ( 65 cm catheter ) . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
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85
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} | {
"id": "C1444754",
"name": "length",
"pos": [
159,
165
]
} |
the composite activities suggest possible differences in certain cancers such as small cell anaplastic lung cancer , lymphoma , leukemia , bladder and ovarian cancer , but sufficiently adequate studies to determine this have not been reported for any tumor . | nichd_parent_of | {
"id": "C0006826",
"name": "cancers",
"pos": [
65,
72
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
117,
125
]
} |
group and individual ability profiles of 89 english 4-year-olds on the mccarthy scales of children 's abilities ( msca ) are presented . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
10,
20
]
} | {
"id": "C0008059",
"name": "children 's",
"pos": [
90,
101
]
} |
in the 11 patients with ventricular arrhythmias , premature complexes were reduced by 90-98 % , and complex ectopy and runs of ventricular tachycardia were abolished ; | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
24,
47
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
127,
150
]
} |
distemper virus is very similar antigenically to measles virus , and the disease produced in ferrets by distemper is a systemic illness quite similar to measles infection in humans . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
73,
80
]
} | {
"id": "C0442893",
"name": "systemic illness",
"pos": [
119,
135
]
} |
distemper virus is very similar antigenically to measles virus , and the disease produced in ferrets by distemper is a systemic illness quite similar to measles infection in humans . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
73,
80
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
161,
170
]
} |
nine of the 13 children had evidence by tympanogram of residual otitis media with effusion ( secretory otitis media ) . | nichd_parent_of | {
"id": "C0029882",
"name": "otitis media",
"pos": [
64,
76
]
} | {
"id": "C0029883",
"name": "secretory otitis media",
"pos": [
93,
115
]
} |
the aim of this investigation was to elucidate whether colles ' fractures in middle-aged women were indicative of generalized bone loss ( osteopenia ) and whether bone mass of the axial and the appendicular skeleton was related to the extent of daily physical activity . | nichd_parent_of | {
"id": "C0220825",
"name": "investigation",
"pos": [
16,
29
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
251,
259
]
} |
the total number of septic complications ( wall abscesses , fistulas , subdiaphragmatic abscesses , septicemia , peritonitis ) , however , was significantly less ( p less than 0.05 ) in the group treated by both preoperative oral antibiotics and peroperative systemic antibiotic therapy ( 3.3 per cent ) than in either g... | nichd_parent_of | {
"id": "C0000833",
"name": "abscesses",
"pos": [
48,
57
]
} | {
"id": "C0038565",
"name": "subdiaphragmatic abscesses",
"pos": [
71,
97
]
} |
in focal neoplastic disease ct and us can be dependably employed when the histological type of the cancer is not required . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplastic disease",
"pos": [
9,
27
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
99,
105
]
} |
in 119 children , predominantly newborns and babies with sepsis , alpha 2-antiplasmin was determined by the use of the chromogenic substrate s-2251 . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
7,
15
]
} | {
"id": "C0021289",
"name": "newborns",
"pos": [
32,
40
]
} |
in 19 tumors , ten of which were stage ii cancers , a non-diploid dna stemline was observed . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
6,
12
]
} | {
"id": "C0006826",
"name": "cancers",
"pos": [
42,
49
]
} |
by means of the present clinical findings it is demonstrated that an improvement of the preoperative nutritional status goes along with a reduction of the postoperative rates of mortality and complications . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
24,
41
]
} | {
"id": "C0009566",
"name": "complications",
"pos": [
192,
205
]
} |
endocrine disorders , diabetes mellitus , drug dependence , and psychogenic alterations have to be discussed as etiologic factors . | nichd_parent_of | {
"id": "C0014130",
"name": "endocrine disorders",
"pos": [
0,
19
]
} | {
"id": "C0011849",
"name": "diabetes mellitus",
"pos": [
22,
39
]
} |
subsequent malignancies associated with carcinoma of the uterine cervix : including an analysis of the effect of patient and treatment parameters on incidence and sites of metachronous malignancies . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
11,
23
]
} | {
"id": "C0302592",
"name": "carcinoma of the uterine cervix",
"pos": [
40,
71
]
} |
these characteristics are described in the form of functional diagrams for flows from 0.3 to 1.0 l . min-1 . 100 g wet lung weight-1 ( wlw ) , for venous pressures from -8 to +14 torr , and for arterial pressures from 16 to 30 torr . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
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21
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
124,
130
]
} |
the quantitative relationships were shown not to change significantly as the transpulmonary pressure changes within the range from 3 to 10 torr . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
4,
16
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
120,
125
]
} |
in 15 dogs with primary rib neoplasms and in 2 dogs with secondary ( presumably metastatic ) rib neoplasms , the clinical signs commonly included dyspnea and a localized swelling on the thoracic wall . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical",
"pos": [
113,
121
]
} | {
"id": "C0013404",
"name": "dyspnea",
"pos": [
146,
153
]
} |
four trials were conducted with a total of 188 crossbred sows to determine the effect of feeding diets supplemented with tallow ( 0 or 8 % ) and choline chloride ( 220 or 770 mg/kg diet ) prior to parturition and during lactation on preweaning pig performance . | nichd_parent_of | {
"id": "C0004927",
"name": "conducted",
"pos": [
17,
26
]
} | {
"id": "C0006147",
"name": "lactation",
"pos": [
220,
229
]
} |
this study indicates that weight-age characteristics estimated from quarterly weights from birth to 1 yr of age and a single annual weight from 1 to 5 yr are adequate for estimating practical weight-age parameters at an early cow age . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
37,
52
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
192,
198
]
} |
since resection of this tumor with reconstructive procedures , either by massive homogenous bone-grafting or artificial joint replacement , is complicated and might cripple the patient if it fails , we propose excision and curettage with bone-grafting as the most suitable method of treatment in the majority of patients... | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
50,
60
]
} | {
"id": "C0087111",
"name": "method",
"pos": [
273,
279
]
} |
in the primovaccinated these viruses were isolated only from those with the negative excretion of polioviruses . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
29,
36
]
} | {
"id": "C0206435",
"name": "polioviruses",
"pos": [
98,
110
]
} |
skin from patients with inherited disorders of connective tissue metabolism ( eds types i-ix , marfan 's syndrome , osteogenesis imperfecta , spondyloepiphyseal dysplasia , and cutis laxa ) has been examined by light and transmission electron microscopy for defects in the collagen and elastic fibrous connective tissue ... | nichd_parent_of | {
"id": "C0410787",
"name": "inherited disorders of connective tissue",
"pos": [
24,
64
]
} | {
"id": "C0024796",
"name": "marfan 's syndrome",
"pos": [
95,
113
]
} |
skin from patients with inherited disorders of connective tissue metabolism ( eds types i-ix , marfan 's syndrome , osteogenesis imperfecta , spondyloepiphyseal dysplasia , and cutis laxa ) has been examined by light and transmission electron microscopy for defects in the collagen and elastic fibrous connective tissue ... | nichd_parent_of | {
"id": "C0410787",
"name": "inherited disorders of connective tissue",
"pos": [
24,
64
]
} | {
"id": "C0029434",
"name": "osteogenesis imperfecta",
"pos": [
116,
139
]
} |
[ parotid tumefaction in autoimmune disease ( sjogren 's syndrome ) . late metastasis of an adenocarcinoma of the kidney ] . | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune disease",
"pos": [
25,
43
]
} | {
"id": "C1527336",
"name": "sjogren 's syndrome",
"pos": [
46,
65
]
} |
it is suggested that prodromata , some symptoms of the headache and recovery phases , as well as the therapeutic effect of sleep , indicate that migraine is primarily a neurological rather than a vascular disorder . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
55,
63
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
145,
153
]
} |
the development of varicella zoster infection was studied in a population of infants under one year of age during three outbreaks of varicella in a semi-closed domiciliary institution for infants in japan . | nichd_parent_of | {
"id": "C0586989",
"name": "varicella zoster infection",
"pos": [
19,
45
]
} | {
"id": "C0008049",
"name": "varicella",
"pos": [
133,
142
]
} |
the eight features used in the index include three dermatoglyphic traits ( hallucal and forefinger pattern , and palmar triradius ) , two measurements of physical traits ( ear length and internipple distance ) , and three other clinical findings ( brushfield spots , wide-spaced first toe , and excess back neck skin ) . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
10,
18
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
176,
182
]
} |
thirteen children had intracranial thrombosis or hemorrhage , four had extremity thrombosis , and one had both an intracranial hemorrhage and an extremity thrombosis . | nichd_parent_of | {
"id": "C0019080",
"name": "hemorrhage",
"pos": [
49,
59
]
} | {
"id": "C0151699",
"name": "intracranial hemorrhage",
"pos": [
114,
137
]
} |
among them 52 subjects ( 4.33 % ) developed nonfebrile seizures after a period of eight months to five years from the first febrile convulsion ( group a ) . | nichd_parent_of | {
"id": "C0036572",
"name": "seizures",
"pos": [
55,
63
]
} | {
"id": "C0009952",
"name": "febrile",
"pos": [
124,
131
]
} |
the procedure was evaluated in a clinical setting to demonstrate its applicability to the study of moxalactam pharmacokinetics in critically ill patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
4,
13
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
18,
27
]
} |
it may be related to several different viral infections , the commonest of which is influenza a . | nichd_parent_of | {
"id": "C0042769",
"name": "viral infections",
"pos": [
39,
55
]
} | {
"id": "C0021400",
"name": "influenza",
"pos": [
84,
93
]
} |
these cases demonstrate that unchanged visual fields do not exclude tumor regrowth , and that computer tomography is indispensable in the follow-up surgically treated pituitary adenomas . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
68,
73
]
} | {
"id": "C0032000",
"name": "pituitary adenomas",
"pos": [
167,
185
]
} |
an atonia of the efferent urinary tract often with fatal complications is present in 46 % of all patients with this syndrome reported in the literature and is unfortunately not included in the acronym didmoad . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
"pos": [
116,
124
]
} | {
"id": "C0043207",
"name": "didmoad",
"pos": [
201,
208
]
} |
of these tumors 28 were benign and 30 malignant , with the commonest benign and malignant tumors being leiomyoma and lymphoma , respectively . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
9,
15
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
80,
96
]
} |
of these tumors 28 were benign and 30 malignant , with the commonest benign and malignant tumors being leiomyoma and lymphoma , respectively . | nichd_parent_of | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
80,
96
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
117,
125
]
} |
cases were aged 35-59 years and had died of chd or other cvd or had a non-fetal mi during a seven-year follow-up . | nichd_parent_of | {
"id": "C0018799",
"name": "of chd",
"pos": [
41,
47
]
} | {
"id": "C0027051",
"name": "mi",
"pos": [
80,
82
]
} |
although in four cases aspergillus had been isolated from tracheal secretions before death , the significance of this finding was not fully appreciated , and in all five the diagnosis of aspergillosis was made at necropsy . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
118,
125
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
174,
183
]
} |
if aspergillus is cultured , and hyphae are present in a fresh smear , and the patient has features of a generalised infection without an obvious site of infection , treatment for aspergillosis should be considered . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
117,
126
]
} | {
"id": "C0004030",
"name": "aspergillosis",
"pos": [
180,
193
]
} |
[ dependence of the psychological condition of infarct patients on the severity of their myocardial infarct ] . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
47,
54
]
} | {
"id": "C0027051",
"name": "myocardial infarct",
"pos": [
89,
107
]
} |
individual variables examined included marital and child-bearing patterns , educational attainments , vocational attainments , perceived parental and peer support , adaptation to prosthesis , and variables relating to general outlook on life and psychological adjustment . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
0,
10
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
51,
56
]
} |
information on the in vivo doubling time of hcg in early pregnancy can be used in more effective diagnosis of early pregnancy disorders such as ectopic pregnancy and spontaneous abortion . | nichd_parent_of | {
"id": "C0151864",
"name": "of",
"pos": [
41,
43
]
} | {
"id": "C0032987",
"name": "ectopic pregnancy",
"pos": [
144,
161
]
} |
the martius procedure is effective for most radiation-induced vaginal fistulas , and the operation is well tolerated by most patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
12,
21
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
89,
98
]
} |
intracellulare has been accompanied by clinical signs of pulmonary mycobacteriosis , i.e . persistence of the cavity in spite of antituberculous treatments reapparition of cough with sputum , general weakness . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
39,
53
]
} | {
"id": "C0010200",
"name": "cough",
"pos": [
172,
177
]
} |
intracellulare has been accompanied by clinical signs of pulmonary mycobacteriosis , i.e . persistence of the cavity in spite of antituberculous treatments reapparition of cough with sputum , general weakness . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
39,
53
]
} | {
"id": "C3714552",
"name": "general weakness",
"pos": [
192,
208
]
} |
eight quantitative first-pass ( fp ) radionuclide angiograms were performed in six children with left ventricular ( lv ) dysfunction without associated lv outflow obstruction and one infant with obstructive cardiomyopathy ( cm ) to define regional and global lv function . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
83,
91
]
} | {
"id": "C0021270",
"name": "infant",
"pos": [
183,
189
]
} |
characteristics measured were egg production , egg weight , eggshell weight , fertility , hatchability , and effects on the progeny . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
0,
15
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
69,
75
]
} |
it is concluded that opiates can significantly modify amygdaloid-kindled seizures , and that brain endorphins may play a role in the development or maintenance of an amygdaloid-kindled seizure focus . | nichd_parent_of | {
"id": "C0036572",
"name": "seizures",
"pos": [
73,
81
]
} | {
"id": "C0751495",
"name": "seizure focus",
"pos": [
185,
198
]
} |
headache subjects were of four types : migraine ( n = 26 ) , muscle contraction ( n = 39 ) , combined migraine-muscle contract ion ( n = 22 ) , and cluster ( n = 12 ) . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
0,
8
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
102,
110
]
} |
the headache groups fell along a continuum , beginning with cluster subjects , who showed only minimal distress , continuing through migraine and combined migraine-muscle contraction , and ending with muscle contraction subjects , who revealed the greatest degree of psychological disturbance . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
4,
12
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
155,
163
]
} |
serum ferritin has been analysed and bone marrow haemosiderin evaluated in 306 patients with malignancies , mostly lymphomas , and in 46 healthy controls . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
93,
105
]
} | {
"id": "C0024299",
"name": "lymphomas",
"pos": [
115,
124
]
} |
cardiovascular diseases are just as much an 'epidemic ' among the indians of south africa as among the the whites , and the 'epidemic ' of ischaemic heart disease , cerebrovascular disease and hypertensive disease is of more serious proportions in indians than in whites . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular diseases",
"pos": [
0,
23
]
} | {
"id": "C0020538",
"name": "hypertensive disease",
"pos": [
193,
213
]
} |
the 'traditional ' sexually transmitted diseases ( syphilis , gonorrhoea and so on ) have now been supplemented but not replaced by a 'second generation ' including chlamydial infections , trichomoniasis , virus diseases ( herpes simplex , hepatitis a and b ) , and protozoal infections in homosexuals . | nichd_parent_of | {
"id": "C0036916",
"name": "sexually transmitted diseases",
"pos": [
19,
48
]
} | {
"id": "C0039128",
"name": "syphilis",
"pos": [
51,
59
]
} |
the 'traditional ' sexually transmitted diseases ( syphilis , gonorrhoea and so on ) have now been supplemented but not replaced by a 'second generation ' including chlamydial infections , trichomoniasis , virus diseases ( herpes simplex , hepatitis a and b ) , and protozoal infections in homosexuals . | nichd_parent_of | {
"id": "C0036916",
"name": "sexually transmitted diseases",
"pos": [
19,
48
]
} | {
"id": "C0018081",
"name": "gonorrhoea",
"pos": [
62,
72
]
} |
the 'traditional ' sexually transmitted diseases ( syphilis , gonorrhoea and so on ) have now been supplemented but not replaced by a 'second generation ' including chlamydial infections , trichomoniasis , virus diseases ( herpes simplex , hepatitis a and b ) , and protozoal infections in homosexuals . | nichd_parent_of | {
"id": "C0042769",
"name": "virus diseases",
"pos": [
206,
220
]
} | {
"id": "C0019159",
"name": "hepatitis",
"pos": [
240,
249
]
} |
ten unselected patients completed the 32-week trial and the results , irrespective of whether the infecting organism was fungal or monilial , are recorded . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
108,
116
]
} | {
"id": "C0016832",
"name": "fungal",
"pos": [
121,
127
]
} |
skeleton , lung , kidney and liver are primary targets for intratracheally instilled 48v with uptake being much greater via the intratracheal route than by the oral route . | nichd_parent_of | {
"id": "C0013153",
"name": "route",
"pos": [
142,
147
]
} | {
"id": "C1527415",
"name": "oral route",
"pos": [
160,
170
]
} |
adult sprague-dawley male rats ( 65 days of age ) received 10 daily treatments of 0 , 200 or 400 mg benomyl/kg/day by gavage . | nichd_parent_of | {
"id": "C0087111",
"name": "treatments",
"pos": [
68,
78
]
} | {
"id": "C0041281",
"name": "gavage",
"pos": [
118,
124
]
} |
radioimmunological tests for carcinoembryonic antigen , antibodies to thyroglobulin , thyrotropin of pituitary , thyroxin and triiodothyronine were run in healthy subjects and patients suffering from cervical thyroid and extrathyroid neoplasms , e. g. nodular goiter , adenoma , cancer , chronic thyroiditis , lymphadeni... | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
234,
243
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
279,
285
]
} |
radioimmunological tests for carcinoembryonic antigen , antibodies to thyroglobulin , thyrotropin of pituitary , thyroxin and triiodothyronine were run in healthy subjects and patients suffering from cervical thyroid and extrathyroid neoplasms , e. g. nodular goiter , adenoma , cancer , chronic thyroiditis , lymphadeni... | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
234,
243
]
} | {
"id": "C0018916",
"name": "hemangioma",
"pos": [
338,
348
]
} |
demonstrating the diagnostic procedures , the authors , by presentation of one of 3 cases , evaluate the value of each procedure separately and stress that the echotomographic procedure is the most reliable in the estimating of the parenchimal structure of the expansive process . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic",
"pos": [
18,
28
]
} | {
"id": "C0041618",
"name": "echotomographic",
"pos": [
160,
175
]
} |
in addition , assessment of the abnormal phenotypic features and the data of other ( laboratory , x-ray , etc . ) examinations revealed 25 ( 3.6 % ) single gene disorders , 25 ( 3.6 % ) recognizable syndromes or associations of unknown aetiology , and in 4 cases ( 0.6 % ) environmental agents were established as possib... | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
161,
170
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
199,
208
]
} |
tests included the minnesota multiphasic personality inventory , the peabody individual achievement test , and the children and adolescent profile . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
77,
87
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
115,
123
]
} |
while sedimentation analysis revealed no basic changes in the sedimentation characteristics of 60-70 s avian myeloblastosis virus ( amv ) rna isolated under different conditions from two sources , electron microscopy exhibited differences in the length distributions of this rna . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
76,
91
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
246,
252
]
} |
in each case , the ct findings were compared with those from the standard radiographs , tomograms , and isotope bone scans as well as with the clinical findings , in regard to tumor detection , diagnosis , and extent . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
143,
160
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
194,
203
]
} |
the histopathologic type of tumor did not correlate with the size , the grade of malignancy , or the location of the mass within the stomach . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
28,
33
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
117,
121
]
} |
thus , reduced insulin clearance and excessive posthepatic delivery of the hormone both contributed to the severe fasting hyperinsulinemia ( 218 microunits/ml ) associated with the other clinical features of the syndrome ( glucose intolerance , primary amenorrhea , polycystic ovaries , hirsutism ) . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
"pos": [
212,
220
]
} | {
"id": "C0032460",
"name": "polycystic ovaries",
"pos": [
266,
284
]
} |
as holoprosencephaly without chromosome defect may be associated with other cns-related anomalies such as mental retardation , mental illness , facial paralysis , endocrine disorders , deafness , spina bifida , and myelomeningocele , we present a family in which one girl had a myelomeningocele , a brother had orbital h... | nichd_parent_of | {
"id": "C0080178",
"name": "spina bifida",
"pos": [
196,
208
]
} | {
"id": "C0025312",
"name": "myelomeningocele",
"pos": [
278,
294
]
} |
overall , the centrality of t-lymphocyte surveillance in controlling spontaneous neoplasms is challenged by the low incidence of malignancy in t cell-deficient animals . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
81,
90
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
129,
139
]
} |
also , the interval between the performance of the procedure and operation was particularly important in the patient with multiple small gallstones or small common duct stones . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
51,
60
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
65,
74
]
} |
a death resulting from this procedure prompted us to evaluate this policy by a retrospective study of 105 elective aneurysm patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
28,
37
]
} | {
"id": "C0220825",
"name": "evaluate",
"pos": [
53,
61
]
} |
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