text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
either the shi test is lacking in specificity or these titers are a reflection of a past or a current infection without any grossly visible abscesses . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
102,
111
]
} | {
"id": "C0000833",
"name": "abscesses",
"pos": [
140,
149
]
} |
from the promising results and absence of side effects of resection of the palmaris longus tendon the procedure can be recommended combined with surgical treatment of dupuytren 's contracture . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
102,
111
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
145,
153
]
} |
all 7 patients with arthritis fulfilled the criteria of the american rheumatism association for rheumatoid arthritis ( ra ) . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
20,
29
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
96,
116
]
} |
galtamycin showed low antitumor activity and was inactive against grampositive and gramnegative organisms and fungi . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
96,
105
]
} | {
"id": "C0016832",
"name": "fungi",
"pos": [
110,
115
]
} |
intranasal inoculation of weanling mice with herpes simplex virus type 2 ( hsv-2 ) provides an experimental infection that closely resembles disseminated and central nervous system hsv infections of human neonates . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
108,
117
]
} | {
"id": "C0007684",
"name": "central nervous system",
"pos": [
158,
180
]
} |
one of the children , treated as a neonate , achieved complete clinical and radiological remission from the disease after nine months , at which point treatment was stopped . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
11,
19
]
} | {
"id": "C0021289",
"name": "neonate",
"pos": [
35,
42
]
} |
a quantitative analysis of leydig cells was performed in 23 testicular biopsies of men with left varicocele and sperm count ranging from zero to 95,000 sperm/mm3 . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
2,
14
]
} | {
"id": "C1514721",
"name": "ranging",
"pos": [
124,
131
]
} |
this neoplasm typically presents in young female patients as a slowly growing mass that may attain large size . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
5,
13
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
78,
82
]
} |
the organism is protected against a possible pathogenic influence of aluminum by a number of physiological mechanisms the most important among which is a regular urine excretion . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
4,
12
]
} | {
"id": "C0450254",
"name": "pathogenic",
"pos": [
45,
55
]
} |
prolonged existence of the tumour , its big size and presence of tumour cells in vessels characterize this tumour as malignant . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
27,
33
]
} | {
"id": "C0006826",
"name": "tumour",
"pos": [
107,
113
]
} |
initial clinical impressions , based solely on history and one neurologic examination , were fairly reliable in establishing the mechanism of stroke ( ie , distinguishing among infarcts , subarachnoid hemorrhages , and parenchymatous hemorrhages ) . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
142,
148
]
} | {
"id": "C2937358",
"name": "parenchymatous hemorrhages",
"pos": [
219,
245
]
} |
the potential significance of this animal reservoir of infection to man is discussed in the light of increasing evidence that giardia is a zoonosis . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
55,
64
]
} | {
"id": "C0043528",
"name": "zoonosis",
"pos": [
139,
147
]
} |
the characteristic length in acute heart failure shifts to the range of 0.2-0.6 micron , while in congestive heart failure the range is 0.2-0.4 micron . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
4,
18
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
19,
25
]
} |
comparison diagnoses included rheumatoid arthritis and other painful conditions of the knee , exclusive of referred or para-articular pain . | nichd_parent_of | {
"id": "C0030193",
"name": "painful",
"pos": [
61,
68
]
} | {
"id": "C0003862",
"name": "articular",
"pos": [
124,
133
]
} |
the pathological changes of legionnaires ' disease pneumonia can thus be reproduced experimentally by the administration of a l. pneumophila tissue-destructive protease , suggesting that production of this protease in vivo during l. pneumophila infection may play an important role in causing the pneumonia . | nichd_parent_of | {
"id": "C0024115",
"name": "the",
"pos": [
0,
3
]
} | {
"id": "C0032285",
"name": "pneumonia",
"pos": [
297,
306
]
} |
elevated levels of a group of substances with digoxin-like immunoreactivity ( dlis ) are present in biological fluids of newborns . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
30,
40
]
} | {
"id": "C0005889",
"name": "fluids",
"pos": [
111,
117
]
} |
opc-8212 , up to 3 mg kg-1 , did not worsen 24 h coronary ligation arrhythmias , while it aggravated ventricular arrhythmias seen 48 h after coronary ligation . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmias",
"pos": [
67,
78
]
} | {
"id": "C0085612",
"name": "ventricular",
"pos": [
101,
112
]
} |
quantitative estimation of the binding parameters was made in each range of postero-anterior sections taken . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
0,
12
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
67,
72
]
} |
during a 14-year follow-up study , abused children who managed to survive the trauma of their childhood and grow up to be well-adjusted individuals were compared with a matched group of children who show , after 14 years , a high degree of psychosocial pathology . | nichd_parent_of | {
"id": "C0027361",
"name": "individuals",
"pos": [
136,
147
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
186,
194
]
} |
two phenotypic features characterize the disease : brief episodic febrile attacks of peritonitis , pleuritis or synovitis recurring from childhood or adolescence and the development of systemic amyloidosis . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
137,
146
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
150,
161
]
} |
host resistance appears to protect against cyathostome disease rather than cyathostome infection , and one manifestation of this resistance appears to be prolongation of the prepatent period . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
55,
62
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
87,
96
]
} |
during the migratory phase of the infection , clinical signs include coughing and a nasal discharge followed by depression and unthriftiness as the worms mature in the gut . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
46,
60
]
} | {
"id": "C0010200",
"name": "coughing",
"pos": [
69,
77
]
} |
during the migratory phase of the infection , clinical signs include coughing and a nasal discharge followed by depression and unthriftiness as the worms mature in the gut . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
46,
60
]
} | {
"id": "C1260880",
"name": "nasal discharge",
"pos": [
84,
99
]
} |
the clinical and pathologic findings of and therapy for such protozoal diseases as equine protozoal myeloencephalitis , toxoplasmosis , sarcocystosis , pneumocytosis , cryptosporidiosis , giardiasis , besnoitiosis , and klossiellosis are discussed . | nichd_parent_of | {
"id": "C0033740",
"name": "protozoal diseases",
"pos": [
61,
79
]
} | {
"id": "C0040558",
"name": "toxoplasmosis",
"pos": [
120,
133
]
} |
the clinical and pathologic findings of and therapy for such protozoal diseases as equine protozoal myeloencephalitis , toxoplasmosis , sarcocystosis , pneumocytosis , cryptosporidiosis , giardiasis , besnoitiosis , and klossiellosis are discussed . | nichd_parent_of | {
"id": "C0033740",
"name": "protozoal diseases",
"pos": [
61,
79
]
} | {
"id": "C0010418",
"name": "cryptosporidiosis",
"pos": [
168,
185
]
} |
fifty-seven of these proved to be sarcomas and the two most common types were malignant schwannoma ( 11 ) and fibrosarcoma ( 9 ) . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcomas",
"pos": [
34,
42
]
} | {
"id": "C0016057",
"name": "fibrosarcoma",
"pos": [
110,
122
]
} |
phase ii trial of mitoxantrone in advanced primary liver cancer : a cancer and leukemia group b study . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
57,
63
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
88,
93
]
} |
previous studies on the validity of the whq , including factor analysis , have shown that migraine and muscular headaches are not mutually exclusive categories . | nichd_parent_of | {
"id": "C0018681",
"name": "whq",
"pos": [
40,
43
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
90,
98
]
} |
tumor-associated neural markers are finding increased application in diagnostic histopathology and in the development of brain tumor therapy . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
36,
43
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
69,
79
]
} |
the illustrations often , of necessity , come from other diseases ( particularly cardiovascular disease ) , where there is considerably more experience . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
57,
65
]
} | {
"id": "C0007222",
"name": "cardiovascular",
"pos": [
81,
95
]
} |
initial coronary venous oxygen tension but not oxygen consumption was strongly correlated with a quantitative index of autoregulation ( -0.052 po2 + 2.01 , r2 = 0.86 ) over the pressure range of 120 to 80 mm hg . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
97,
109
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
186,
191
]
} |
intravenous vasodilator agents were used for 19.62 hr ( +/- 4.33 ) in the general anesthesia group vs 1.4 hr ( +/- 0.44 ) in the regional block anesthesia group ( p less than .02 ) . | nichd_parent_of | {
"id": "C0002903",
"name": "anesthesia",
"pos": [
82,
92
]
} | {
"id": "C0002911",
"name": "regional",
"pos": [
129,
137
]
} |
accumulation and defective beta-oxidation of very long chain fatty acids in zellweger 's syndrome , adrenoleukodystrophy and refsum 's disease variants . | nichd_parent_of | {
"id": "C0043459",
"name": "zellweger 's syndrome",
"pos": [
76,
97
]
} | {
"id": "C0162309",
"name": "adrenoleukodystrophy",
"pos": [
100,
120
]
} |
in zellweger 's syndrome , and to a lesser extent in infantile refsum 's disease , there was an increase in 24:0 , 26:0 , 26:1 , and a number of even longer chain fatty acids , while in the x-linked form of adrenoleukodystrophy these changes were less pronounced . | nichd_parent_of | {
"id": "C0043459",
"name": "zellweger 's syndrome",
"pos": [
3,
24
]
} | {
"id": "C0162309",
"name": "x-linked",
"pos": [
190,
198
]
} |
residual lignoceric acid beta-oxidation activity varied from approximately 15 % in zellweger syndrome up to 50 % in x-linked adrenoleukodystrophy . | nichd_parent_of | {
"id": "C0043459",
"name": "zellweger syndrome",
"pos": [
83,
101
]
} | {
"id": "C0162309",
"name": "x-linked adrenoleukodystrophy",
"pos": [
116,
145
]
} |
in zellweger 's syndrome , and possibly in infantile refsum 's disease , it is probable that this defect is secondary to a primary abnormality affecting the structure and/or function of peroxisomes , while the primary defect in x-linked adrenoleukodystrophy may be confined to a pathway specific for the oxidation of ver... | nichd_parent_of | {
"id": "C0043459",
"name": "zellweger 's syndrome",
"pos": [
3,
24
]
} | {
"id": "C0162309",
"name": "x-linked adrenoleukodystrophy",
"pos": [
228,
257
]
} |
chemotherapy for disseminated disease generally gives disappointing results , since only a minority of tumors respond and survival benefit is marginal . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
30,
37
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
103,
109
]
} |
we think the applied procedure may be valuable for evaluation of any imaging system for clinical use . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
21,
30
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
51,
61
]
} |
the diabetes mellitus occurring in these patients is clinically indistinguishable from classic type i diabetes mellitus . | nichd_parent_of | {
"id": "C0011849",
"name": "diabetes mellitus",
"pos": [
4,
21
]
} | {
"id": "C0011854",
"name": "type i diabetes",
"pos": [
95,
110
]
} |
employing animals trained to discriminate either ( + ) -amphetamine or ( +/- ) -dom from saline in a two-lever operant procedure , stimulus generalization studies were conducted to evaluate members of a series of methoxy-substituted , and related , phenylisopropylamines . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
119,
128
]
} | {
"id": "C0220825",
"name": "evaluate",
"pos": [
181,
189
]
} |
these include optimising non-pharmacological means of controlling symptoms , using the smallest doses of antiasthma drugs necessary to control symptoms , basing the decision to use a drug on its benefit-to-risk ratio , avoiding recently introduced drugs ( for which safety in pregnancy has not been adequately establishe... | nichd_parent_of | {
"id": "C0013153",
"name": "route",
"pos": [
348,
353
]
} | {
"id": "C1527415",
"name": "oral route of administration",
"pos": [
375,
403
]
} |
bipolar and referential responses correlated to the surface p300 auditory potential complex ( components n2 , p3 and n4 ) were studied in different subcortical structures of parkinsonian and epileptic patients with implanted electrodes used as an electrophysiological procedure for surgical treatment . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
268,
277
]
} | {
"id": "C0543467",
"name": "surgical treatment",
"pos": [
282,
300
]
} |
the proportion of patients with elevated plasma ld and the mean plasma ld increased with advancing stage and increasing tumour bulk for both seminoma and nsgct . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
120,
126
]
} | {
"id": "C0205851",
"name": "nsgct",
"pos": [
154,
159
]
} |
difluoromethylornithine ( dfmo ) , an irreversible inhibitor of ornithine decarboxylase , and human leukocyte interferon ( ifn-alpha ) have synergistic anti-tumor activities in vivo in b 16 melanoma and in vitro against several human cancer cell lines . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
157,
162
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
234,
240
]
} |
using a semiquantitative immunohistochemical procedure , we have evaluated the 24 hour circadian rhythm of n-acetylserotonin- and melatonin-like immunoreactivity in the retina of male hooded rats that have pigmented eyes . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
45,
54
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
65,
74
]
} |
immunoblotting analysis of cytokeratin and vimentin polypeptides of the individual genital ducts were in agreement with the immunocytochemical results obtained in 15- and 16-day-old fetuses . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
72,
82
]
} | {
"id": "C0015965",
"name": "fetuses",
"pos": [
182,
189
]
} |
forty-four subjects ( 67 aided ears ) fitted by the new procedure were evaluated by paired comparison judgments of the intelligibility and pleasantness of speech . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
56,
65
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
71,
80
]
} |
the radiographic manifestations of this colitis are nonspecific and usually mimic the findings of ulcerative colitis with diffuse mucosal ulceration or granulomatous colitis with aphthous ulceration and skip areas . | nichd_parent_of | {
"id": "C0009319",
"name": "colitis",
"pos": [
40,
47
]
} | {
"id": "C0009324",
"name": "ulcerative colitis",
"pos": [
98,
116
]
} |
the genetic determination of high-density-lipoprotein cholesterol ( hdl-c ) levels was evaluated using segregation analysis techniques in a large multigenerational kindred with a high prevalence of coronary heart disease and myocardial infarction . | nichd_parent_of | {
"id": "C0018799",
"name": "of",
"pos": [
26,
28
]
} | {
"id": "C0027051",
"name": "myocardial",
"pos": [
225,
235
]
} |
the most common complication was in pin tract infection requiring incision , drainage , and oral antibiotics in 16 patients ( 43 % ) . | nichd_parent_of | {
"id": "C0009566",
"name": "complication",
"pos": [
16,
28
]
} | {
"id": "C0038941",
"name": "infection",
"pos": [
46,
55
]
} |
patients with arthritis alone developed erythema nodosum ( 35 % ) or aphthous stomatitis more often ( 21 % ) than patients without spondylarthritis+ ( 6 % and 12 % , respectively ) . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
14,
23
]
} | {
"id": "C0949690",
"name": "spondylarthritis",
"pos": [
131,
147
]
} |
our findings indicate that gdm entails genotypic as well as phenotypic diversity and may include patients with slowly-evolving type i diabetes mellitus , as well as patients with type ii diabetes mellitus , and women with asymptomatic diabetes which antedated the pregnancy ( i.e . pregestational diabetes mellitus ) . | nichd_parent_of | {
"id": "C0085207",
"name": "gdm",
"pos": [
27,
30
]
} | {
"id": "C3828492",
"name": "pregestational",
"pos": [
282,
296
]
} |
individual rabbit fetuses in utero were injected intramuscularly with either 2.0 units protamine zinc insulin or saline at 23 days gestation after surgical reduction of litter size to 4 fetuses at 9 days gestation . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
0,
10
]
} | {
"id": "C0015965",
"name": "fetuses",
"pos": [
186,
193
]
} |
twenty-four hours after injection of insulin into individual fetal rabbits from normal litters at 23 or 27 days gestation insulin-injected fetuses were hyperinsulinaemic and euglycaemic , but had significantly higher plasma glucocorticoid concentrations than saline-injected littermates . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
50,
60
]
} | {
"id": "C0015965",
"name": "fetuses",
"pos": [
139,
146
]
} |
the piribedil test appears to possess good specificity vis a vis migraine , enabling a differential diagnosis from atypical periodic headache , a condition difficult to consider as migraine or psychogenic headache on clinical grounds alone . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
133,
141
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
181,
189
]
} |
the piribedil test appears to possess good specificity vis a vis migraine , enabling a differential diagnosis from atypical periodic headache , a condition difficult to consider as migraine or psychogenic headache on clinical grounds alone . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
133,
141
]
} | {
"id": "C0033893",
"name": "psychogenic headache",
"pos": [
193,
213
]
} |
we evaluated the physical characteristics and contrast-dose-detail performance of 11 rare-earth and three calcium tungstate screen-film systems . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
3,
12
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
17,
25
]
} |
over 100 inherited metabolic diseases , all chromosomal abnormalities and a number of major congenital malformations can already be diagnosed at relatively early stages of fetal development . | nichd_parent_of | {
"id": "C0019247",
"name": "inherited",
"pos": [
9,
18
]
} | {
"id": "C0008625",
"name": "chromosomal abnormalities",
"pos": [
44,
69
]
} |
bone marrow transplantation is increasingly used to treat a spectrum of diseases in man , including immune and genetic disorders , hematological diseases , and cancer . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
72,
80
]
} | {
"id": "C0019247",
"name": "genetic disorders",
"pos": [
111,
128
]
} |
bone marrow transplantation is increasingly used to treat a spectrum of diseases in man , including immune and genetic disorders , hematological diseases , and cancer . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
72,
80
]
} | {
"id": "C0018939",
"name": "hematological diseases",
"pos": [
131,
153
]
} |
these diseases include aplastic anemia , acute myelogenous leukemia , acute lymphoblastic leukemia , chronic myelogenous leukemia , and selected immune and genetic disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
6,
14
]
} | {
"id": "C0019247",
"name": "genetic disorders",
"pos": [
156,
173
]
} |
within birth cohorts , cross-sectional analyses of height , body mass , blood pressure and disorders -- such as bronchial asthma , allergic rhinitis , diabetes , psychiatric diagnoses and such genetic conditions as familial mediterranean fever -- point to clear ethnic differences . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
91,
100
]
} | {
"id": "C0019247",
"name": "genetic conditions",
"pos": [
193,
211
]
} |
within birth cohorts , cross-sectional analyses of height , body mass , blood pressure and disorders -- such as bronchial asthma , allergic rhinitis , diabetes , psychiatric diagnoses and such genetic conditions as familial mediterranean fever -- point to clear ethnic differences . | nichd_parent_of | {
"id": "C0019247",
"name": "genetic conditions",
"pos": [
193,
211
]
} | {
"id": "C0031069",
"name": "familial mediterranean fever",
"pos": [
215,
243
]
} |
the present report summarizes the results of a search for hemoglobinopathies in 142,171 persons in xinjiang , the results of structural analyses of abnormal hemoglobins in 134 families , and the incidence and distribution of abnormal hemoglobins and the thalassemias in eight ethnic groups or nationalities . | nichd_parent_of | {
"id": "C0019045",
"name": "hemoglobinopathies",
"pos": [
58,
76
]
} | {
"id": "C0039730",
"name": "thalassemias",
"pos": [
254,
266
]
} |
although the gross clinical appearance of the tumors in all six patients was of a large and fixed mass which might on clinical grounds be expected to contain hypoxic cells , we have observed drug binding to hypoxic regions in only two , a rapidly growing small cell lung cancer ( sclc ) and a malignant melanoma . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
46,
52
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
98,
102
]
} |
eighteen dogs had no clinical signs of disease and were referred for evaluation of a previously detected cardiac murmur , 5 dogs had congestive right-sided heart failure , and 5 dogs were examined for exercise intolerance or syncope . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
21,
35
]
} | {
"id": "C0039070",
"name": "syncope",
"pos": [
225,
232
]
} |
quantitative immunoblot analyses of seven human liver specimens disclosed two immunoreactive proteins whose total concentration varied over a 6-fold range . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
0,
12
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
149,
154
]
} |
injuries provoked and treatment instituted are described in relation to children admitted for severe abdominal contusions between 1970 and 1985 . | nichd_parent_of | {
"id": "C3263723",
"name": "injuries",
"pos": [
0,
8
]
} | {
"id": "C0009938",
"name": "contusions",
"pos": [
111,
121
]
} |
the levels of these antibodies in iga-deficient adults with and without frequent respiratory infections and children under immunosuppressive therapy for malignant disease were compared to those in normal adults and infants 1-7 months of age . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
108,
116
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
215,
222
]
} |
fifteen older individuals ( 7 to 40 months of age ) developed titers of f and g antibodies comparable to those in children who were infected with rsv . | nichd_parent_of | {
"id": "C0027361",
"name": "individuals",
"pos": [
14,
25
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
114,
122
]
} |
whereas immunoglobulin a ( iga ) antitoxin titer increases in saliva ( 44 % ) and breast milk ( 29 % ) specimens after vaccination were less frequent than in intestinal fluid ( 76 % ) , antitoxin responses in saliva and breast milk occurred in 80 to 90 % of the patients after disease . | nichd_parent_of | {
"id": "C0005889",
"name": "fluid",
"pos": [
169,
174
]
} | {
"id": "C0026131",
"name": "breast milk",
"pos": [
220,
231
]
} |
a comparison of the frequency and magnitude of antibody response in different body fluids with those in intestinal lavage fluid revealed no extraintestinal antibody that directly reflected the intestinal immunity . | nichd_parent_of | {
"id": "C0005889",
"name": "body fluids",
"pos": [
78,
89
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
156,
164
]
} |
of the 552 virus isolates , 507 were adenoviruses , 41 were polioviruses , and 4 were herpes simplex viruses ( hsv ) . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
"pos": [
11,
16
]
} | {
"id": "C0206435",
"name": "polioviruses",
"pos": [
60,
72
]
} |
recognition of this finding allows a correct diagnosis of partial or complete duplication of the renal collecting system and prevents a false impression of an intrarenal mass lesion . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
20,
27
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
45,
54
]
} |
the procedures were evaluated by speech discrimination testing , using nonsense syllables in noise , and by paired comparison judgments of the intelligibility and pleasantness of running speech . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
4,
14
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
20,
29
]
} |
low-income children participating in wic were significantly less likely to have low iron intakes than children who were eligible by income level but not participating in wic . | nichd_parent_of | {
"id": "C0008059",
"name": "wic",
"pos": [
37,
40
]
} | {
"id": "C0021270",
"name": "wic",
"pos": [
170,
173
]
} |
the percentage of children with low intakes of vitamin a and calcium did not significantly vary by household income level or by participation in wic . | nichd_parent_of | {
"id": "C0008059",
"name": "wic",
"pos": [
145,
148
]
} | {
"id": "C0021270",
"name": "wic",
"pos": [
145,
148
]
} |
apart from serving as an indication of the presence of a dry eye condition , the questionnaire results may successfully identify individuals who are at risk for developing dry eye problems at a later time , especially those individuals exposed to provocative factors such as contact lens wear . | nichd_parent_of | {
"id": "C0015397",
"name": "of the",
"pos": [
36,
42
]
} | {
"id": "C0013238",
"name": "dry eye",
"pos": [
172,
179
]
} |
twenty-seven had major gi disorders , the most common being duodenal stenosis ( ds , nine ) , gastroesophageal reflux ( ger , five ) , imperforate anus ( five ) , and hirschsprung 's disease ( four ) . | nichd_parent_of | {
"id": "C0017178",
"name": "gi disorders",
"pos": [
23,
35
]
} | {
"id": "C0238093",
"name": "duodenal stenosis",
"pos": [
60,
77
]
} |
twenty-seven had major gi disorders , the most common being duodenal stenosis ( ds , nine ) , gastroesophageal reflux ( ger , five ) , imperforate anus ( five ) , and hirschsprung 's disease ( four ) . | nichd_parent_of | {
"id": "C0017178",
"name": "gi disorders",
"pos": [
23,
35
]
} | {
"id": "C0017168",
"name": "ger",
"pos": [
120,
123
]
} |
whether the disease is related to occupation , social class , marital status , stress , infection , diet , smoking , and oral contraceptives is less certain . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
12,
19
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
88,
97
]
} |
the adoptive transfer of delayed-type hypersensitivity ( dth ) into naive recipients requires the interaction of two functionally distinct ly-1+ t cells : and i-j- cell effector cell for dth which transfers antigen-specific dth only into animals whose suppressive mechanisms have been compromised , and and i-j+ cell whi... | nichd_parent_of | {
"id": "C0020517",
"name": "dth",
"pos": [
57,
60
]
} | {
"id": "C0020522",
"name": "dth",
"pos": [
392,
395
]
} |
ltb4-like immunoreactivity from atopic dermatitis suction blister fluid cochromatographed on reverse-phase high-pressure liquid chromatography with authentic ltb4 , thus excluding cross-reaction of the ltb4-antibody with arachidonic acid or monohydroxyeicosatetraenoic acids . | nichd_parent_of | {
"id": "C0005889",
"name": "fluid",
"pos": [
66,
71
]
} | {
"id": "C0003241",
"name": "antibody",
"pos": [
207,
215
]
} |
many unvaccinated contacts living in the same household as the index case under conditions of maximum exposure , however , escaped not only the disease but also infection . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
144,
151
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
161,
170
]
} |
it was the first recognized outbreak of this organism in the united states since 1982 , when two outbreaks led to its recognition as a pathogen . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
45,
53
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
135,
143
]
} |
serological testing indicated that 7.5 % of children were infected with leishmania each year and that the ratio of disease to infection was 1:18.5 for the whole area and 1:6.5 for the section with the highest prevalence of disease . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
115,
122
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
126,
135
]
} |
the multifactorial etiologic spectrum in iliofemoral thrombosis is basically the same as in calf vein thrombosis . | nichd_parent_of | {
"id": "C0040053",
"name": "thrombosis",
"pos": [
53,
63
]
} | {
"id": "C0042487",
"name": "vein thrombosis",
"pos": [
97,
112
]
} |
the assay has been applied in the management of hydatidiform mole , invasive mole and choriocarcinoma , indicating its usefulness because of the increase in sensitivity roughly 25 times or 10 times as great as hemagglutination or hcg-beta ria assay . | nichd_parent_of | {
"id": "C0020217",
"name": "hydatidiform mole",
"pos": [
48,
65
]
} | {
"id": "C0008493",
"name": "invasive mole",
"pos": [
68,
81
]
} |
to evaluate how the physical profile differs between term and postterm fetuses , a statistical and an allometric analyses were made on 6658 cases delivered at 20 weeks of gestation or more in our hospital for last 40 years from 1940s to 1970s , by using the physical parameters such as the weight , the height and so on ... | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
3,
11
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
258,
266
]
} |
the in vitro inhibitory activities of four currently used antimycotic agents ( clotrimazole , econazole , miconazole and cyclopirox-olamine ) against 304 fungal isolates comprising 51 species from 14 genera of moulds and yeasts , using a serial dilution procedure , were studied . | nichd_parent_of | {
"id": "C0016832",
"name": "fungal",
"pos": [
154,
160
]
} | {
"id": "C0369241",
"name": "moulds",
"pos": [
210,
216
]
} |
the in vitro inhibitory activities of four currently used antimycotic agents ( clotrimazole , econazole , miconazole and cyclopirox-olamine ) against 304 fungal isolates comprising 51 species from 14 genera of moulds and yeasts , using a serial dilution procedure , were studied . | nichd_parent_of | {
"id": "C0016832",
"name": "fungal",
"pos": [
154,
160
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
221,
227
]
} |
over the range of values observed in utero , there were significant inverse correlations between the log plasma insulin level and the mean plasma concentrations of glucose , lactate , fructose and alpha-amino-nitrogen in individual intact and pancreatectomized fetuses . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
221,
231
]
} | {
"id": "C0015965",
"name": "fetuses",
"pos": [
261,
268
]
} |
especially the enzyme-linked immunoassays for detecting the early immune reaction against virus-infections ( e.g . rubella , measles , and others ) show irregular positive results , if the tests are performed in samples containing igm rheumatoid factor . | nichd_parent_of | {
"id": "C0042769",
"name": "virus-infections",
"pos": [
90,
106
]
} | {
"id": "C0035920",
"name": "rubella",
"pos": [
115,
122
]
} |
the focus of most behavioral studies on melatonin relate to sleep , arousal levels and circadian rhythms of alertness . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
18,
28
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
60,
65
]
} |
a marked reduction in tumour size indicate a radiosensitive tumour ( germ cell tumour or pineoblastoma ) and the radiation field should be extended to total cns who receives 30 gy . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
22,
28
]
} | {
"id": "C0205851",
"name": "germ cell tumour",
"pos": [
69,
85
]
} |
furthermore , the metabolism of putrescine in brain tumors was related to tumor type and appeared to correlate with the degree of malignancy . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
52,
57
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
130,
140
]
} |
applied to 55 patients with tumoral and non tumoral cns disease , the new test detects average levels of csf desmosterol in tumor bearing patients that are tenfold higher than in the absence of cns neoplasia . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
56,
63
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
124,
129
]
} |
it was also used to evaluate the lead burden of persons suspected of having elevated lead exposure at the workplace , and to assay the lead levels in urban and rural children . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
48,
55
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
166,
174
]
} |
both ex-patients and controls grew below the 25th percentile of british longitudinal standards , but the male ex-patients were heavier , and perhaps taller , than the controls for most of their childhood and adolescence . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
194,
203
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
208,
219
]
} |
in almost all the children multiple , rather than single , fetal , neonatal and infant risks were found , and along with the multiple risks , multiple time periods were found during which the risks occurred . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
18,
26
]
} | {
"id": "C0021270",
"name": "infant",
"pos": [
80,
86
]
} |
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