text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
history and clinical findings supported a diagnosis of ergotism due to heavy use of ergotamine suppositories . | nichd_parent_of | {
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dysgenesis of the deep venous system was found in alobar , semilobar , and lobar holoprosencephaly , a finding helpful in diagnosis , especially of the lobar type . | nichd_parent_of | {
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} | {
"id": "C0011900",
"name": "diagnosis",
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disease of the palate may be local in nature or may reflect a systemic condition . | nichd_parent_of | {
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} | {
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an accurate diagnosis requires the evaluation of a wide range of signs and symptoms through both a history and a clinical examination . | nichd_parent_of | {
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} | {
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in dba/2 mice bearing transplanted , syngeneic p815 mastocytoma , macrophage accumulation was impaired in the tumor when the cancer grew intraperitoneally . | nichd_parent_of | {
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that interference with monocyte inflammation required a threshold number of tumor cells was consistent with an increase in tumor-associated macrophages proportional to tumor growth during early cancer . | nichd_parent_of | {
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it was demonstrated that both the value and duration of acceleration played a certain role in the pathogenesis of functional disorders of the respiratory system and atelectasis ; | nichd_parent_of | {
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} | {
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the group of patients is made up of 30 cases of germ cell tumors ( 70 % dysgerminomas ) and 29 cases of stromal tumors ( 62 % granulosa cell tumors ) . | nichd_parent_of | {
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with u.s. age-specific proportional cancer mortality for white males as a standard , the observed/expected ratio of leukaemia deaths was 5.62 ( 6 observed , 1.1 expected ) among the 146 former nuclear workers . | nichd_parent_of | {
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} | {
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126,
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the pathophysiology of hearing loss as a sequela of meningitis and the possible explanations for absence of hearing loss in viral meningitis are discussed . | nichd_parent_of | {
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} | {
"id": "C0025297",
"name": "viral meningitis",
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about 50 % of cynomolgus monkeys infected with rabies virus could be protected from the disease with human interferon which was administered at a total dose of 1 -- 10 million units per animal either intramuscularly 24 hours after infection or by intralumbar injection up to 11 days after . | nichd_parent_of | {
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although it is difficult to make quantitative comparisons between plate and suspension tests , both systems appeared to be responsive to the same dose ranges for the individual nitrosamines . | nichd_parent_of | {
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treatment should be surgical , consisting of total extirpation of the tumour with a margin of healthy tissue . | nichd_parent_of | {
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} | {
"id": "C0015250",
"name": "total extirpation",
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symptomatology was characterized by confusion and hallucination ( visual hallucinations , loss of space-time relationships , etc . ) associated with neurovegetal symptomatology ascribable to the active principles contained in the preparation used : mydriasis , disturbances in visual accomodation , dryness of the fauces... | nichd_parent_of | {
"id": "C0018524",
"name": "hallucination",
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} | {
"id": "C0233763",
"name": "visual hallucinations",
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} |
the rise in the temperature increases the general resistence of the fish organism and favours the formation of immunological reaction to hyperinfection that causes the further fall in the parasite abundance . | nichd_parent_of | {
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} | {
"id": "C0030498",
"name": "parasite",
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188,
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} |
quantitative studies of formation of this compound revealed a dose-dependent relationship between the level of its occurence in liver dna and afb1 doses over the range 0.125-1.0 mg/kg . | nichd_parent_of | {
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the radiological appearance and main features of calcifications of the basal ganglia in metabolic , toxic and hypoxemic disorders , degenerative and systemic diseases , tumors as well as infectious and parasitic lesions are described and demonstrated by typical radiographs . | nichd_parent_of | {
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120,
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} | {
"id": "C0442893",
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} |
the radiological appearance and main features of calcifications of the basal ganglia in metabolic , toxic and hypoxemic disorders , degenerative and systemic diseases , tumors as well as infectious and parasitic lesions are described and demonstrated by typical radiographs . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
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120,
129
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} | {
"id": "C0027651",
"name": "tumors",
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169,
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} |
the radiological appearance and main features of calcifications of the basal ganglia in metabolic , toxic and hypoxemic disorders , degenerative and systemic diseases , tumors as well as infectious and parasitic lesions are described and demonstrated by typical radiographs . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
120,
129
]
} | {
"id": "C0009450",
"name": "infectious",
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187,
197
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} |
lesion detectability was assessed by a data processing system which evaluated average lesion-to-background activity ratios for each patient examination . | nichd_parent_of | {
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77
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} | {
"id": "C0031809",
"name": "patient examination",
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132,
151
]
} |
serum ferritin concentrations have been estimated in 30 patients with untreated megaloblastic anaemia , 27 with addisonian pernicious anaemia . | nichd_parent_of | {
"id": "C0002888",
"name": "megaloblastic anaemia",
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80,
101
]
} | {
"id": "C0002892",
"name": "addisonian pernicious anaemia",
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112,
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} |
the premise is based on a comprehensive review of the literature relative to the risk factors applied to intracranial aneurysms and personal experience in dealing with the combination of problems of aneurysms diagnosed in association with other intracranial aneurysms , vascular malformations , neoplasms , trauma , and ... | nichd_parent_of | {
"id": "C0002940",
"name": "aneurysms",
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118,
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]
} | {
"id": "C0007766",
"name": "intracranial aneurysms",
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245,
267
]
} |
the diseases reported most frequently by the adult population of working age were cardiovascular and musculoskeletal disorders , each with prevalence rates of 200 persons per 1,000 population . | nichd_parent_of | {
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} | {
"id": "C0026857",
"name": "musculoskeletal disorders",
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101,
126
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} |
regional lymphadenectomy in patients with level iv and v disease in whom the tumors drained to a single node basin revealed occult metastases in 25 per cent of the patients and , therefore , appears warranted as prophylactic treatment . | nichd_parent_of | {
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} | {
"id": "C0027651",
"name": "tumors",
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77,
83
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} |
prediction equations have been evolved for the assessment of vital capacity , total lung capacity , and the single breath carbon monoxide transfer factor in haemoglobin ss and haemoglobin sc disease . | nichd_parent_of | {
"id": "C0002895",
"name": "haemoglobin ss",
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157,
171
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} | {
"id": "C0019034",
"name": "haemoglobin sc disease",
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176,
198
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} |
in 20 normal healthy donors its serum level was 3.57 +/- 1.62 microgram/ml ( mean +/- sd ) , and it was increased significantly in certain diseases , such as acute leukemias , cardiovascular disorders , malignancies , renal failure , systemic lupus erythematosus and sepsis . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
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139,
147
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} | {
"id": "C0007222",
"name": "cardiovascular disorders",
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176,
200
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} |
one group of animals developed clinical signs of cerebral ischemia and stroke very rapidly and often died within 12 hours . | nichd_parent_of | {
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45
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} | {
"id": "C0011065",
"name": "died",
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101,
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} |
the following complications were observed : formation of para-articular ossifications ( 7 ) , wound infection ( 1 ) , dislocation of the endoprothesis socket from the acetabulum ( 1 ) , fracture of the femur ( 2 ) , laxity of the prothesis pedicle ( 1 ) , thrombophlebitis ( 2 ) , postoperative bleeding ( 1 ) . | nichd_parent_of | {
"id": "C0009566",
"name": "complications",
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27
]
} | {
"id": "C0032788",
"name": "postoperative bleeding",
"pos": [
281,
303
]
} |
under the influence of such factors as physical , overtension , overcooling of the organism , osteochondrosis may acquire a pathogenic significance in the appearance of some diseases . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
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91
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} | {
"id": "C0450254",
"name": "pathogenic",
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124,
134
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} |
increased activities of hmp enzymes in some tumors indicated that the potential activity of the hmp in some ( but not all ) tumors of the nervous system is greater than that of cerebral cortex . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
44,
50
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} | {
"id": "C0027766",
"name": "tumors of the nervous system",
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124,
152
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} |
oedema of the umbilical cord was found to have no significance for the infant , but their placentae were significantly heavier , without signs of generalized oedema . | nichd_parent_of | {
"id": "C0013604",
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6
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} | {
"id": "C0151603",
"name": "generalized oedema",
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146,
164
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} |
the immersion procedure makes the demonstration and evaluation of soft tissue swelling and periarticular oedema easier . | nichd_parent_of | {
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} | {
"id": "C0220825",
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} |
in ocular disease , the most common cause of compromise ( and of infection with such opportunistic pathogens as the herpeviruses , many gram-negative bacteria , numerous fungi and toxoplasma ) is the topical use of corticosteroids and antibiotic-corticosteroid preparations . | nichd_parent_of | {
"id": "C0012634",
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10,
17
]
} | {
"id": "C0009450",
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} |
the incidence of whooping cough in children has decreased by at least 50 % , but the proportion of cases occurring in infants younger than 12 weeks of age has doubled to 30 % of all cases . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
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35,
43
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} | {
"id": "C0021270",
"name": "infants",
"pos": [
118,
125
]
} |
formerly most young infants acquired their illness from siblings or other children , but in the recent period adults in the household were the most common source of infection to neonates and young infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
74,
82
]
} | {
"id": "C0021289",
"name": "neonates",
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178,
186
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} |
formerly most young infants acquired their illness from siblings or other children , but in the recent period adults in the household were the most common source of infection to neonates and young infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
74,
82
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
197,
204
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} |
an exceptionally high incidence of congenital rubella syndrome ( crs ) has been noted in ryukan children who were infants in utero during an extensive rubella epidemic in the ryukyu islands in 1964 through the spring of 1965 . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
96,
104
]
} | {
"id": "C0021270",
"name": "infants",
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114,
121
]
} |
specific disorders covered are clotting factor deficiencies , hemophilia a , factor viii inhibitors , von willebrand disease , hemophilia b ( christmas disease ) , other congenital coagulation disorders , acquired deficiency of factors ii , vii , ix and x , and defibrination syndrome . | nichd_parent_of | {
"id": "C0272315",
"name": "clotting factor deficiencies",
"pos": [
31,
59
]
} | {
"id": "C0042974",
"name": "von",
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102,
105
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} |
since membranous nephropathy in patients with malignancies has been attributed to a tumor antigen-antibody complex form of glomerulonephritis , an attempt was made to implicate tumor antigens and/or renal tubular epithelial antigens in the pathogenesis of membranous nephropathy in our patient with renal cell carcinoma ... | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
46,
58
]
} | {
"id": "C0007134",
"name": "renal cell carcinoma",
"pos": [
299,
319
]
} |
since membranous nephropathy in patients with malignancies has been attributed to a tumor antigen-antibody complex form of glomerulonephritis , an attempt was made to implicate tumor antigens and/or renal tubular epithelial antigens in the pathogenesis of membranous nephropathy in our patient with renal cell carcinoma ... | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
"pos": [
123,
141
]
} | {
"id": "C0017665",
"name": "membranous nephropathy",
"pos": [
256,
278
]
} |
however , their association temporally suggests that they were related , and our immunologic studies demonstrate that tumor antigen-antibody complexes are not invariably involved in the pathogenesis of malignancy-associated membranous nephropathy . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
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118,
123
]
} | {
"id": "C0006826",
"name": "malignancy",
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202,
212
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} |
low-dose initiation and slow increment of both 8-methoxypsoralen and uva is probably a reasonable regimen for benign dermatoses such as psoriasis because it will allow enough time for the skin to become more protected , while the therapeutic results are as satisfactory as in a high-dose schedule . | nichd_parent_of | {
"id": "C0037274",
"name": "dermatoses",
"pos": [
117,
127
]
} | {
"id": "C0033860",
"name": "psoriasis",
"pos": [
136,
145
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} |
the procedure described is safe and should be routine in seizure or syncope evaluation , when a meticulous history still leaves room for doubt . | nichd_parent_of | {
"id": "C0184661",
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4,
13
]
} | {
"id": "C0220825",
"name": "evaluation",
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} |
as demonstrated in this large series , the procedure can be performed safely and efficiently on an outpatient basis , with the use of only topical anesthesia . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
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43,
52
]
} | {
"id": "C0002903",
"name": "anesthesia",
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147,
157
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} |
twenty-one of these patients had visualization of the biliary ducts without opacification of the gallbladder , a roentgenographic finding that was considered diagnostic of acute cholecystitis . | nichd_parent_of | {
"id": "C0037088",
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130,
137
]
} | {
"id": "C0011900",
"name": "diagnostic",
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158,
168
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} |
with a sufficiently large number of autopsies , the author recommends to carry out pathoanatomical analysis of the quality of the clinical diagnosis of perinatal disease separately by perinatal periods of death , groups of prematurely born and born in time , stillborns and dying newborns , and by groups of diseases typ... | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
308,
316
]
} | {
"id": "C0021053",
"name": "disease",
"pos": [
436,
443
]
} |
despite very few surgical techniques for this purpose have been described and applied clinically , although a tremendous effort has been made for the complete removal of the malignancy and the avoidance of recurrence up to the present [ 1 -- 4 , 6 ] . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical techniques",
"pos": [
17,
36
]
} | {
"id": "C0015250",
"name": "complete removal",
"pos": [
150,
166
]
} |
analytical methods of determination , investigations of stability and the behaviour of the substance in artificial gastric and intestinal fluids are the bases for the formulation of an oral preparation of 14-hydroxy-3beta- [ 4-o-methyl-alpha-l-rhamnopyranosyl ) oxy ] -14beta-bufa-4,20,22-tr ienolide ( meproscillarin , ... | nichd_parent_of | {
"id": "C0439861",
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91,
100
]
} | {
"id": "C0005889",
"name": "fluids",
"pos": [
138,
144
]
} |
procedures are described for selecting the gain and frequency response of hearing aids for deaf children and for evaluating aided hearing . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
0,
10
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
113,
123
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} |
the first experiment successfully replicated the finding that smooth pursuit eye-tracking ( spet ) performance recorded using electronsystagmographic techniques statistically differentiates between groups of clinically diagnosed shizophrenic patients and normal controls . | nichd_parent_of | {
"id": "C0037088",
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49,
56
]
} | {
"id": "C0011900",
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219,
228
]
} |
there was a loss of vasomotor tone in 48 per cent of patients with peripheral neuropathy and in 12 per cent of those without neuropathy ( p less than 0.01 ) . | nichd_parent_of | {
"id": "C0031117",
"name": "peripheral",
"pos": [
67,
77
]
} | {
"id": "C0442874",
"name": "neuropathy",
"pos": [
125,
135
]
} |
the effect of oxytocin on jaundice was independent of gestational age at birth , sex , race , epidural anaesthesia , method of delivery , and birth weight , each of which was significantly associated with neonatal jaundice . | nichd_parent_of | {
"id": "C0022346",
"name": "jaundice",
"pos": [
26,
34
]
} | {
"id": "C0022353",
"name": "neonatal jaundice",
"pos": [
205,
222
]
} |
the actions of a new type of ergolene derivative , mpme ( ( 5r , 8r ) -8- ( 4-p-methoxyphenyl-1-piperazinyl methyl ) -6-methylergolene ) , have been evaluated on central catecholamine ( ca ) neurons in the rat by means of a combined biochemical , histochemical and behavioural analysis . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
149,
158
]
} | {
"id": "C1160858",
"name": "behavioural analysis",
"pos": [
265,
285
]
} |
hence any screening program designed to detect kidney disease in schoolchildren would not prevent chronic renal failure , since at that age renal parenchymal damage seems to be irreversible . | nichd_parent_of | {
"id": "C0022658",
"name": "kidney disease",
"pos": [
47,
61
]
} | {
"id": "C0022661",
"name": "chronic renal failure",
"pos": [
98,
119
]
} |
in may 1972 , the cancer and leukemia group b initiated a randomized study comparing the effectiveness of ccnu and methyl-ccnu in patients with advanced malignant lymphomas , including hodgkin 's disease ( hd ) , lymphosarcoma ( lys ) and reticulum cell sarcoma ( rcs ) . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
18,
24
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
38,
43
]
} |
in may 1972 , the cancer and leukemia group b initiated a randomized study comparing the effectiveness of ccnu and methyl-ccnu in patients with advanced malignant lymphomas , including hodgkin 's disease ( hd ) , lymphosarcoma ( lys ) and reticulum cell sarcoma ( rcs ) . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
18,
24
]
} | {
"id": "C0024299",
"name": "lymphosarcoma",
"pos": [
213,
226
]
} |
electron microscopic studies of the epithelial tumor cells displayed large amounts of cytoplasmic microfilaments similar to those present in the extracellular amyloid masses . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
47,
52
]
} | {
"id": "C0577559",
"name": "masses",
"pos": [
167,
173
]
} |
the results indicate that these two lipid-soluble folate antagonists give similar qualitative and quantitative effects over a concentration range of from 1 to 100 micrometer . | nichd_parent_of | {
"id": "C0392762",
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98,
110
]
} | {
"id": "C1514721",
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140,
145
]
} |
the paper outline the contribution that recent diagnostic methods -- such as endoscopic retrograde cholangiopancreatography , computed tomography and ultrasonography -- have made to solution of the problem and establishes the criteria for emergency or elective operation . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic methods",
"pos": [
47,
65
]
} | {
"id": "C0041618",
"name": "ultrasonography",
"pos": [
150,
165
]
} |
a semi automated procedure for the determination of 3-methoxy-4-hydroxy-mandelic acid ( hmma ) in urine has been evaluated . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
17,
26
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
113,
122
]
} |
the regular function of the prothesis was evaluated on the basis of the physical , radiological and electrocardiographic data . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
42,
51
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
72,
80
]
} |
results indicate , that the procedure will be essential as well in evaluation as in analysis of nature and frequency of such complains by its superior presentation of intrahepatic bilestasis and functional mechanisms of the biliary system including the sphincter of oddi . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
28,
37
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
67,
77
]
} |
passive immunization has proven an important complementary method for protection of an infected organism against rabies in the very first phase after virus contact . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
96,
104
]
} | {
"id": "C0042776",
"name": "virus",
"pos": [
150,
155
]
} |
the low flows are of interest in the warming procedure of patients with hypothermia following trauma and the blood transfusion applied to infant anaesthesia . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
45,
54
]
} | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
145,
156
]
} |
the precise pathogenesis of one of the most common cutaneous disorders , diaper dermatitis , has not yet been completely established , perhaps in part because relatively little histopathological knowledge has been obtained . | nichd_parent_of | {
"id": "C0037274",
"name": "of",
"pos": [
25,
27
]
} | {
"id": "C0011974",
"name": "diaper",
"pos": [
73,
79
]
} |
scalpel scrapings provided information only on the morphology of individual spores and hyphae , while biopsies and cyanoacrylate adhesive slides demonstrated the topography of the disease as well as providing information on how the infection spreads and recurs . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
180,
187
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
232,
241
]
} |
the procedure is illustrated by its application to a project for training and evaluating use of a vibrotacile-electrotactile aid to lipreading . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
4,
13
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
78,
88
]
} |
thus , some instances of cephalothin nephropathy appear to be toxic in nature with a histologic picture of acute tubular necrosis , whereas others exhibit signs of hypersensitivity including rash , eosinophilia , and interstitial nephritis . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
37,
48
]
} | {
"id": "C0022672",
"name": "acute tubular necrosis",
"pos": [
107,
129
]
} |
thus , some instances of cephalothin nephropathy appear to be toxic in nature with a histologic picture of acute tubular necrosis , whereas others exhibit signs of hypersensitivity including rash , eosinophilia , and interstitial nephritis . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
37,
48
]
} | {
"id": "C0027707",
"name": "interstitial",
"pos": [
217,
229
]
} |
to better understand the recovery process of infants with lower respiratory tract disease due to respiratory syncytial virus , the production of interferon by 129 children ( ages 10 days to 24 months ) with rsv infection was compared to that of 20 children with influenza ( ages 1 to 36 months ) , and 37 children with p... | nichd_parent_of | {
"id": "C0042769",
"name": "disease due to",
"pos": [
82,
96
]
} | {
"id": "C0035235",
"name": "rsv infection",
"pos": [
207,
220
]
} |
to better understand the recovery process of infants with lower respiratory tract disease due to respiratory syncytial virus , the production of interferon by 129 children ( ages 10 days to 24 months ) with rsv infection was compared to that of 20 children with influenza ( ages 1 to 36 months ) , and 37 children with p... | nichd_parent_of | {
"id": "C0042769",
"name": "disease due to",
"pos": [
82,
96
]
} | {
"id": "C0021400",
"name": "influenza",
"pos": [
323,
332
]
} |
( 3 ) drug-induced , caused by drug therapy for various life-threatening diseases , and ( 4 ) chronic pancreatitis , with or without an anatomic abnormality . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
73,
81
]
} | {
"id": "C0302142",
"name": "anatomic abnormality",
"pos": [
136,
156
]
} |
the tumour represented 1.97 per cent of total medical admissions and constituted 40 per cent of all malignancies seen . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
4,
10
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
100,
112
]
} |
all of arisen tumors were diagnosed fibrosarcoma histologically and with every recurrence the aggravation of malignancy of tumors was shown . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
14,
20
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
109,
119
]
} |
traditionally , the teachings of sexuality to handicapped persons have run into objections resulting from society 's negative attitude toward the handicapped and parental apprehension regarding the decision-making skills of their children in relation to acceptable and unacceptable sexual behaviors . | nichd_parent_of | {
"id": "C0027361",
"name": "persons",
"pos": [
58,
65
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
230,
238
]
} |
malignant diseases of infancy , childhood and adolescence : psychological and social support of the patient and family . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
32,
41
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
46,
57
]
} |
the structure and replication of human leukocyte mitochondrial dna ( mtdna ) was investigated in healthy young adult males ( 23 -- 37 years old ) , middle-aged males ( 42 -- 52 years old ) with secondary polycythemia , and elderly males ( 80 -- 89 years old ) who exhibited different degrees of age-related disease syndr... | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
307,
314
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
315,
324
]
} |
the procedures and tests included are an electrocardiogram , urinalysis , complete blood count , sigmoidoscopy , tuberculin skin test , two-view chest x-ray , cardiovascular treadmill stress test , and an automated 12-channel blood chemistry test . | nichd_parent_of | {
"id": "C0022885",
"name": "tests",
"pos": [
19,
24
]
} | {
"id": "C0041290",
"name": "tuberculin skin test",
"pos": [
113,
133
]
} |
these polypoid tumors have a small epidermoid carcinomatous part and a major part with sarcoma like appearance . | nichd_parent_of | {
"id": "C0006826",
"name": "carcinomatous",
"pos": [
46,
59
]
} | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
87,
94
]
} |
it is suggested that this finding of increased metabolism of cortisol by lymphocytes from patients with different types of malignancy other than lymphoma may provide the basis for a new diagnostic aid . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
123,
133
]
} | {
"id": "C0024299",
"name": "lymphoma",
"pos": [
145,
153
]
} |
the prognostic implications of a past history of ischaemic heart disease , site of infarction , ectopic ventricular dysrhythmias ( ventricular premature beats ( vpb ) more than one in 10 sinus beats , and/or ventricular tachycardia ( vt ) , ventricular fibrillation ( vf ) , atrioventricular blocks ( avb ) , bundle bran... | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular dysrhythmias",
"pos": [
104,
128
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
208,
231
]
} |
the prognostic implications of a past history of ischaemic heart disease , site of infarction , ectopic ventricular dysrhythmias ( ventricular premature beats ( vpb ) more than one in 10 sinus beats , and/or ventricular tachycardia ( vt ) , ventricular fibrillation ( vf ) , atrioventricular blocks ( avb ) , bundle bran... | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular dysrhythmias",
"pos": [
104,
128
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
241,
265
]
} |
[ diabetes insipidus , diabetes mellitus , optic nerve atrophy , and deafness -- an autosomal recessive syndrome ( didmoad-syndrome ) ( author 's transl ) ] . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
"pos": [
104,
112
]
} | {
"id": "C0043207",
"name": "didmoad-syndrome",
"pos": [
115,
131
]
} |
to determine whether tumors containing carcinoembryonic antigen could be detected by administration of a radiolabeled , affinity-purified , goat lgg having 70 per cent immunoreactivity against carcinoembryonic antigen , 18 patients with a history of cancer of diverse histopathology received an average total dose of 1.0... | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
21,
27
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
250,
256
]
} |
these data and those of other authors working on other glycosides ( incleding digoxin ) and other species ( including newborn children ) lead to the conclusion that digitalis glycosides in new born species are excreted at a lower rate and incorporated in the body tissues at a higher rate than in adults . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
126,
134
]
} | {
"id": "C0021289",
"name": "new born",
"pos": [
189,
197
]
} |
tumor markers as sequential monitors or quantitative measures of disease and response to therapy have similarly demonstrated limited utility , related to the heterogeneity of the tumors and to the lack of a precise quantitative relationship between circulating tm levels and tumor volume or mass . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
65,
72
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
179,
185
]
} |
tumor markers as sequential monitors or quantitative measures of disease and response to therapy have similarly demonstrated limited utility , related to the heterogeneity of the tumors and to the lack of a precise quantitative relationship between circulating tm levels and tumor volume or mass . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
179,
185
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
291,
295
]
} |
the theories are presented not as iron-clad rules , but rather as guidelines to be used in selecting leadership behavior appropriate to circumstantial needs , which can vary widely in nursing . | nichd_parent_of | {
"id": "C0004927",
"name": "behavior",
"pos": [
112,
120
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
184,
191
]
} |
since the morbidity and mortality which is found in obese subjects arises primarily from cardiovascular disease in general , and coronary heart disease in particular , nutritional influences have obvious relevance to the prevention of coronary heart disease . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular",
"pos": [
89,
103
]
} | {
"id": "C0018799",
"name": "the",
"pos": [
217,
220
]
} |
arrhenius plots of initial accumulation rates are triphasic , with transitions or characteristic temperatures of 20 degrees and 9.5 degrees . at the higher temperature , the mobility of the chloretracycline , as measured by fluorescence polarization , is markedly altered . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
82,
96
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
97,
109
]
} |
in correlative electron spin resonance experiments on the partitioning of a lipid-soluble spin label , the same characteristic temperatures detected in the fluorescence studies were measured . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
112,
126
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
127,
139
]
} |
these data suggest that different probes may respond to either or both of the characteristic temperatures describing the lateral phase separation . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
78,
92
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
93,
105
]
} |
between these characteristic temperatures the chlortetracycline transport system is most intimately associated with relatively immobile lipids that are surrounded by a more mobile lipid phase . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
14,
28
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
29,
41
]
} |
if each organism acted independently , then with small infecting inocula all the organisms in nasopharynx , blood , or cerebrospinal fluid should be descended from a single bacterium . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
81,
90
]
} | {
"id": "C0004611",
"name": "bacterium",
"pos": [
173,
182
]
} |
complementary rnas ( crnas ) to hpv-1 , hpv-2 , and viruses obtained from two patients with epidermodysplasia verruciformis ( j.d . hpv and j.k. hpv ) were used in crna.dna filter hybridization experiments . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
52,
59
]
} | {
"id": "C0021344",
"name": "hpv",
"pos": [
145,
148
]
} |
the author in his present paper reports the results of studies made in an effort to reconstructively validate a method of self-imaging during childhood and adolescence . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
142,
151
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
156,
167
]
} |
in 110 patients with different malignant tumors various pharmacological substances ( ridol ( g. richter , hungary ) , arphonad ( hoffmann , switzerland ) , xavin ( chinoin , hungary ) etc . ) were used in lymphography to improve inflow of contrast medium and visualization of lymph vessels and nodes . | nichd_parent_of | {
"id": "C1254351",
"name": "pharmacological",
"pos": [
56,
71
]
} | {
"id": "C0009924",
"name": "contrast",
"pos": [
239,
247
]
} |
only rostock virus caused sicked sickness or death in ducks , 9/10 intranasally infected and 6/7 in contact birds showed clinical signs and 2/10 intranasally infected and 3/7 in contact ducks died . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
121,
135
]
} | {
"id": "C0011065",
"name": "died",
"pos": [
192,
196
]
} |
intracranial disease was successfully controlled and recurrences were prevented but patients eventually died from relapse of their systemic disease . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
13,
20
]
} | {
"id": "C0442893",
"name": "systemic disease",
"pos": [
131,
147
]
} |
the goal of investigation was to find the physical data , viz . changes of volume , pressure resistance after 1 and 24 hours , creep value of gamma-2-free amalgams ( dispersion type ) , to compare the values to each other and to those of conventional amalgams . | nichd_parent_of | {
"id": "C0220825",
"name": "investigation",
"pos": [
12,
25
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
42,
50
]
} |
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