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of the seven patients of the first group who were at risk of gvhd ( excluding two cases of early death ) , five developed a minimal-to-moderately severe acute gvhd and in two cases chronic gvhd ensued .
nichd_parent_of
{ "id": "C0018133", "name": "gvhd", "pos": [ 61, 65 ] }
{ "id": "C0856825", "name": "acute gvhd", "pos": [ 153, 163 ] }
of the seven patients of the first group who were at risk of gvhd ( excluding two cases of early death ) , five developed a minimal-to-moderately severe acute gvhd and in two cases chronic gvhd ensued .
nichd_parent_of
{ "id": "C0018133", "name": "gvhd", "pos": [ 61, 65 ] }
{ "id": "C0867389", "name": "chronic gvhd", "pos": [ 181, 193 ] }
they demonstrate that a one-log t-lymphocyte reduction of the marrow inoculum , when combined with cyclosporin a prophylaxis after major histocompatibility complex ( mhc ) -matched transplantation , is still associated with a considerable incidence of gvhd , whereas a two-log reduction of t-lymphocytes may provide full...
nichd_parent_of
{ "id": "C0018133", "name": "gvhd", "pos": [ 252, 256 ] }
{ "id": "C0856825", "name": "acute gvhd", "pos": [ 340, 350 ] }
clinical signs of disease included intensive basking , anorexia , lethargy , flaccid limb paralysis , stomatitis , and dermatitis .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 55, 63 ] }
clinical signs of disease included intensive basking , anorexia , lethargy , flaccid limb paralysis , stomatitis , and dermatitis .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0023380", "name": "lethargy", "pos": [ 66, 74 ] }
he classified the disorder as a `` '' nevrose , '' '' meaning a neurologic disorder without a known pathologic lesion , and found little benefit from therapies available at the time , including belladonna and ergot products .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 18, 26 ] }
{ "id": "C0027765", "name": "a neurologic disord", "pos": [ 62, 81 ] }
venous dilatation has been reported in high flow vein grafts , blood access v fistulas and rarely , proximal to traumatic av fistulas of the lower extremities .
nichd_parent_of
{ "id": "C0016169", "name": "fistulas", "pos": [ 78, 86 ] }
{ "id": "C0003855", "name": "av fistulas", "pos": [ 122, 133 ] }
adhesion is considered in terms of the attraction and repulsion forces operative as the organism approaches a substratum surface , as well as in terms of the surface free energies of the bacterium , the substratum and the liquid phase .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 88, 96 ] }
{ "id": "C0004611", "name": "bacterium", "pos": [ 187, 196 ] }
before their deaths , 4 cranes did not develop clinical signs , whereas the other 3 cranes were lethargic and ataxic , with high aspartate transaminase , gamma-glutamyl transferase , and lactic acid dehydrogenase activities , and high uric acid concentrations .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 47, 61 ] }
{ "id": "C0023380", "name": "lethargic", "pos": [ 96, 105 ] }
the similarity of lesions and the finding of inclusions diagnostic of canine distemper virus ( cdv ) in some skunks indicated that cdv may be the main cause of neurologic disease in nonrabid skunks .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 34, 41 ] }
{ "id": "C0011900", "name": "diagnostic", "pos": [ 56, 66 ] }
the frequency of l. monocytogenes-reactive t cells depended on the number and virulence of the infecting organisms , the highest sublethal dose of virulent bacteria inducing the highest frequency .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 105, 114 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 156, 164 ] }
these findings directly demonstrate the existence of multiple mutations in the ca vaccine strain , a property that may provide reliably and stably attenuated vaccines that derive their six internal genes from the ca a/ann arbor/6/60 donor strain .
nichd_parent_of
{ "id": "C0042210", "name": "vaccine", "pos": [ 82, 89 ] }
{ "id": "C0042211", "name": "attenuated vaccines", "pos": [ 147, 166 ] }
most patients are severe alcoholics , but they may have other endocrine disorders , such as diabetes mellitus , hyperuricemia , or hyperlipidemia .
nichd_parent_of
{ "id": "C0014130", "name": "endocrine disorders", "pos": [ 62, 81 ] }
{ "id": "C0011849", "name": "diabetes mellitus", "pos": [ 92, 109 ] }
an endocrine aetiology may easily be missed in a patient with relatively minor muscle stiffness , pain and cramps , such as the man described by yunus et al ( 1981 ) whose myalgia , 'arthralgia ' and muscle tenderness vanished completely within four days of taking physiological replacement doses of cortisone acetate as...
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 98, 102 ] }
{ "id": "C0231528", "name": "myalgia", "pos": [ 172, 179 ] }
an endocrine aetiology may easily be missed in a patient with relatively minor muscle stiffness , pain and cramps , such as the man described by yunus et al ( 1981 ) whose myalgia , 'arthralgia ' and muscle tenderness vanished completely within four days of taking physiological replacement doses of cortisone acetate as...
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 98, 102 ] }
{ "id": "C0003862", "name": "arthralgia", "pos": [ 183, 193 ] }
however , when leukemia involves the mucous membranes , acute myeloid leukemia ( acute monocytic and acute myelomonocytic leukemia ) is the most likely diagnosis .
nichd_parent_of
{ "id": "C0023467", "name": "acute myeloid leukemia", "pos": [ 56, 78 ] }
{ "id": "C0023479", "name": "acute myelomonocytic", "pos": [ 101, 121 ] }
while awareness of diseases by these opportunistic fungi is increasing , details of their pathogenesis are largely unknown , although ability of the host to inhibit spore germination appears to be central to resistance to infection .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 19, 27 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 222, 231 ] }
when they do occur , clinical findings and contrast dacryocystography generally are utilized to establish the diagnosis .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 21, 38 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 110, 119 ] }
tumors in proximity to the globe , wrap around the scleral-uveal coat causing no indentation but displacement of the globe from the mass effect .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 0, 6 ] }
{ "id": "C0577559", "name": "mass", "pos": [ 132, 136 ] }
analysis of the rate constants might be useful for interpreting tumor nature and predicting its malignancy .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 64, 69 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 96, 106 ] }
among the 16 children there were 2 with lipoma of the corpus callosum , 1 neonate with aneurysm of the vein of galen , 2 with agenesis of the corpus callosum , 1 newborn with a large cyst in the quadrigeminal plate cistern , 3 with a dandy-walker malformation , 5 with a posterior fossa cyst , and 2 with a chiari ii mal...
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 13, 21 ] }
{ "id": "C0021289", "name": "newborn", "pos": [ 162, 169 ] }
a series of linear measurements on computed tomography of the brain was performed in 481 children ( from newborns up to 5 years of age ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 89, 97 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 105, 113 ] }
evolutionary stages under discussion are : the self-organization of spontaneously formed biomolecules into early precursors of life ( protobionts ) , their stepwise evolution via ( postulated ) protocells to ( postulated ) progenotes and the darwinian evolution from progenotes to the three kingdoms of contemporary orga...
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 316, 325 ] }
{ "id": "C0004611", "name": "eubacteria", "pos": [ 345, 355 ] }
the antiglobulin neutralization test : a procedure for evaluating the efficacy of washing red cells for antibody elution .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 41, 50 ] }
{ "id": "C0220825", "name": "evaluating", "pos": [ 55, 65 ] }
the antiglobulin neutralization test , a procedure designed to detect neutralizing concentrations of igg , is compared with the sulfosalicylic acid test and the indirect antiglobulin test as a means of evaluating efficacy of protein removal by washing red cells prior to antibody elution .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 41, 50 ] }
{ "id": "C0220825", "name": "evaluating", "pos": [ 202, 212 ] }
an indirect enzyme linked immunosorbent assay ( elisa ) procedure was evaluated against the serum neutralisation test ( snt ) for the detection of antibodies to infectious bovine rhinotracheitis virus ( bovine herpesvirus type l ) , using 2028 sera from 166 dairy and 172 beef cattle herds .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 56, 65 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 70, 79 ] }
a comparable investigation between our results and those of existing studies used the long nozzles on those characteristics revealed that both the bubble penetration depth and the gas entrainment rate differed depending on the nozzle length ;
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 108, 123 ] }
{ "id": "C1444754", "name": "length", "pos": [ 234, 240 ] }
it has been demonstrated that con a bound hollow fiber prepared according to the procedure outlined here can be successfully used to construct glucose affinity sensor for operation in the physiological range of glucose concentrations .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 81, 90 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 171, 180 ] }
small passerine birds ( serinus canaria , carduelis chloris , carduelis carduelis , carduelis spinus , carduelis cannabina , pyrrhula pyrrhula ) showed clinical signs consisting of anorexia , prostration , weight loss , diarrhoea and dyspnoea accompanied by a high mortality rate .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 152, 166 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 181, 189 ] }
small passerine birds ( serinus canaria , carduelis chloris , carduelis carduelis , carduelis spinus , carduelis cannabina , pyrrhula pyrrhula ) showed clinical signs consisting of anorexia , prostration , weight loss , diarrhoea and dyspnoea accompanied by a high mortality rate .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 152, 166 ] }
{ "id": "C0013404", "name": "dyspnoea", "pos": [ 234, 242 ] }
clinical signs , death , virus excretion and immune response were measured in 2-week-old chickens , turkeys , quail and ducks infected by intramuscular , intranasal and contact routes with eight influenza viruses of h5 subtype .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0011065", "name": "death", "pos": [ 17, 22 ] }
five cytopathic viruses morphologically resembling rotaviruses were isolated from duck faeces in chicken kidney cell cultures using conventional methods .
nichd_parent_of
{ "id": "C0042776", "name": "viruses", "pos": [ 16, 23 ] }
{ "id": "C0035870", "name": "rotaviruses", "pos": [ 51, 62 ] }
one of the isolates , designated f-29 strain , was identified as an avian rotavirus from the following : ribonucleic acid in the viral core , virus growth in the cytoplasm , resistance to chloroform , acid and heating , partial stabilisation to molar magnesium chloride and rotavirus-like morphology by electron microsco...
nichd_parent_of
{ "id": "C0042776", "name": "virus", "pos": [ 78, 83 ] }
{ "id": "C0035870", "name": "rotavirus", "pos": [ 274, 283 ] }
detection and treatment of chlamydia infections are as important as that of other sexually transmitted diseases ( stds ) such as gc , syphilis , trichomoniasis , etc .
nichd_parent_of
{ "id": "C0036916", "name": "sexually transmitted diseases", "pos": [ 82, 111 ] }
{ "id": "C0039128", "name": "syphilis", "pos": [ 134, 142 ] }
ectopic pregnancies have been reported in distal tubal segments following tubal sterilization procedures ( metz kgp , mastroianni jr l : tubal pregnancy subsequent to transperitoneal migration of spermatozoa .
nichd_parent_of
{ "id": "C0032987", "name": "ectopic pregnancies", "pos": [ 0, 19 ] }
{ "id": "C0032994", "name": "tubal pregnancy", "pos": [ 137, 152 ] }
according to this view , the appearance of spiral arms is a consequence of the differential rotation of the galaxy and the characteristic divergence of correlation lengths for continuous phase transitions .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 123, 137 ] }
{ "id": "C1444754", "name": "lengths", "pos": [ 164, 171 ] }
flame ionization permitted determination with a coefficient of variation ranging from 10 to 27 % at the picomolar level , whereas quantitative chemical ionization mass spectrometry afforded sensitivities for poly-beta-hydroxyalkanoate constituuents in the attomolar range .
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 130, 142 ] }
{ "id": "C1514721", "name": "range", "pos": [ 266, 271 ] }
the organisms were attached to the surfaces at cell densities of approximately 5 x 10 cells cm ( diatoms ) and 5 x 10 cells cm ( bacteria ) .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 4, 13 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 129, 137 ] }
clinical signs of pruritis and focal erythematous skin lesions developed in various pigs from four and a half to 13 weeks after exposure .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0033774", "name": "pruritis", "pos": [ 18, 26 ] }
clinical signs included sudden illness or death with or without observed depression , reluctance to move , scours or fever .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0011065", "name": "death", "pos": [ 42, 47 ] }
clinical signs included sudden illness or death with or without observed depression , reluctance to move , scours or fever .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0015967", "name": "fever", "pos": [ 117, 122 ] }
quantitative comparisons between theoretical ( co ( 2 ) or hco ( 3 ) ( - ) transport ) and experimental time-courses of ( 14 ) c incorporation , over the ph range of 5.2 to 7.5 , indicate that the specific activity of extracellular co ( 2 ) , rather than hco ( 3 ) ( - ) , is the appropriate predictor of the intracellul...
nichd_parent_of
{ "id": "C0392762", "name": "quantitative", "pos": [ 0, 12 ] }
{ "id": "C1514721", "name": "range", "pos": [ 157, 162 ] }
a survey was conducted to assess the attitudes towards breastfeeding , its prevalence and duration among kuwaiti married women .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 13, 22 ] }
{ "id": "C0006147", "name": "breastfeeding", "pos": [ 55, 68 ] }
herniated disc , while not the most common cause of low back pain , is the most common reason for surgery to relieve back pain .
nichd_parent_of
{ "id": "C0030193", "name": "pain", "pos": [ 61, 65 ] }
{ "id": "C0004604", "name": "back pain", "pos": [ 117, 126 ] }
the fungus grew on both substrates and was the dominant mould on the non-autoclaved grain .
nichd_parent_of
{ "id": "C0016832", "name": "fungus", "pos": [ 4, 10 ] }
{ "id": "C0369241", "name": "mould", "pos": [ 56, 61 ] }
expectations of equally novel , highly thermostable biocatalysts and specialty chemicals from such organisms remain high but must be tempered with the laboratory realities of manipulating unusual bacteria whose growth characteristics are as yet poorly defined .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 99, 108 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 196, 204 ] }
these air quality patterns in turn serve as the data base in a two-step procedure for the identification and ranking of the most desirable monitoring locations ( step 1 ) and the removal of redundancies in spatial coverage among the desired locations ( step 2 . ) the performance of the air quality simulation model , a ...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 72, 81 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 364, 373 ] }
loving is predicated upon the dynamic synthesis of trusting , autonomous , and creative relationships during childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 109, 118 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 123, 134 ] }
since p. milioides has some leaf characteristics intermediate to c3 and c4 species , its photosynthetic response to irradiance and temperature was compared to the closely related c3 species , p. laxum and p. boliviense and to p. prionitis .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 33, 48 ] }
{ "id": "C0039476", "name": "temperature", "pos": [ 131, 142 ] }
because prepartal stress did not markedly disturb the mother 's retrieving and crouching behavior , disturbances in postpartal nursing behavior do not seem to account for the abnormal sexual behavior of male offspring as adults .
nichd_parent_of
{ "id": "C0004927", "name": "behavior", "pos": [ 89, 97 ] }
{ "id": "C0006147", "name": "nursing", "pos": [ 127, 134 ] }
in a patient with congenital heart disease , an mctc interval greater than 0.03 sec and recording of an anterior tricuspid leaflet near the apex of the heart strongly suggest the diagnosis of ebstein 's malformation .
nichd_parent_of
{ "id": "C0152021", "name": "congenital heart disease", "pos": [ 18, 42 ] }
{ "id": "C0013481", "name": "ebstein 's malformation", "pos": [ 192, 215 ] }
tumors of the human nervous system ( neuroblastomas , an ependymoma , a medulloblastoma , and a schwannoma ) obtained during surgery have been cultured organotypically by the method of wolff .
nichd_parent_of
{ "id": "C0027766", "name": "tumors of the", "pos": [ 0, 13 ] }
{ "id": "C0027819", "name": "neuroblastomas", "pos": [ 37, 51 ] }
tumors of the human nervous system ( neuroblastomas , an ependymoma , a medulloblastoma , and a schwannoma ) obtained during surgery have been cultured organotypically by the method of wolff .
nichd_parent_of
{ "id": "C0027766", "name": "tumors of the", "pos": [ 0, 13 ] }
{ "id": "C0014474", "name": "ependymoma", "pos": [ 57, 67 ] }
tumors of the human nervous system ( neuroblastomas , an ependymoma , a medulloblastoma , and a schwannoma ) obtained during surgery have been cultured organotypically by the method of wolff .
nichd_parent_of
{ "id": "C0027766", "name": "tumors of the", "pos": [ 0, 13 ] }
{ "id": "C0025149", "name": "medulloblastoma", "pos": [ 72, 87 ] }
the scintigraphically visible areas of infarction , measured using interactive computer-aided techniques , were compared subsequently with independent histologic measurements of myocardial infarct size .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 39, 49 ] }
{ "id": "C0027051", "name": "myocardial infarct", "pos": [ 178, 196 ] }
clinical signs and symptoms of nausea and vomiting , dysphagia , diplopia , dilated pupils , and dry throat occurred with great frequency , forming a diagnostic pentad .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0042963", "name": "vomiting", "pos": [ 42, 50 ] }
clinical signs and symptoms of nausea and vomiting , dysphagia , diplopia , dilated pupils , and dry throat occurred with great frequency , forming a diagnostic pentad .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0012569", "name": "diplopia", "pos": [ 65, 73 ] }
to assess the influence of diabetes mellitus on bone metabolism , we measured skeletal mass in the forearms of 35 patients with juvenile diabetes on insulin and 101 stable patients with adult-onset diabetes , on diet alone , insulin , or oral hypoglycemic agents .
nichd_parent_of
{ "id": "C0011849", "name": "diabetes mellitus", "pos": [ 27, 44 ] }
{ "id": "C0011854", "name": "juvenile diabetes", "pos": [ 128, 145 ] }
this paper presents in detail the symptomatology and findings on examination of 642 patients suffering from a variety of lower gastrointestinal disorders , such as colonic and rectal cancer , diverticular disease , crohn 's disease , and ulcerative colitis .
nichd_parent_of
{ "id": "C0017178", "name": "gastrointestinal disorders", "pos": [ 127, 153 ] }
{ "id": "C0010346", "name": "crohn 's disease", "pos": [ 215, 231 ] }
the investigation illustrates the extensive variability in the physical characteristics of plasmid dna from r factor-harboring strains .
nichd_parent_of
{ "id": "C0220825", "name": "investigation", "pos": [ 4, 17 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 63, 71 ] }
the presence of proteins in the dej did not correlate with the presence of active renal disease at the time of biopsy nor with previously documented active nephritis .
nichd_parent_of
{ "id": "C0022658", "name": "renal disease", "pos": [ 82, 95 ] }
{ "id": "C0027697", "name": "nephritis", "pos": [ 156, 165 ] }
these observations may have implications in clinical allergy since substances similar to the pertussis factor might be produced by other microbial organisms and these substances could modulate the immunologic response of individuals to common allergens .
nichd_parent_of
{ "id": "C0439861", "name": "substances", "pos": [ 67, 77 ] }
{ "id": "C0002092", "name": "allergens", "pos": [ 243, 252 ] }
the onset of clinical signs for groups 1 and 2 occurred on days 4-6 and 7-10 , respectively , with fever , anorexia , and depression .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 13, 27 ] }
{ "id": "C0015967", "name": "fever", "pos": [ 99, 104 ] }
the onset of clinical signs for groups 1 and 2 occurred on days 4-6 and 7-10 , respectively , with fever , anorexia , and depression .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 13, 27 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 107, 115 ] }
a monovalent , zonally purified , inactivated influenza b vaccine was administered to 29 children , 3 to 6 years of age , and 16 infants , 12 to 28 months of age , as a single dose of 0.25 ml containing 250 chick cell agglutinating units .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 89, 97 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 129, 136 ] }
it is felt that this procedure can be used not only for the relief of severe aortic annular stenosis but also for other forms of severe left ventricular outflow tract obstruction such as idiopathic hypertrophic subaortic stenosis and particularly in the patients who have experienced poor results with one of the known s...
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 21, 30 ] }
{ "id": "C0543467", "name": "surgical procedures", "pos": [ 319, 338 ] }
articular inflammation in patients with transient polyarthritis responded in three to seven days to aspirin , acetominophen and/or bedrest alone and rashes disappeared spontaneously .
nichd_parent_of
{ "id": "C0003864", "name": "articular inflammation", "pos": [ 0, 22 ] }
{ "id": "C0162323", "name": "polyarthritis", "pos": [ 50, 63 ] }
fifteen patients had mental disorders , including eight with personality disorders , three with schizophrenia , three with organic brain syndromes , and one with manic depressive psychosis .
nichd_parent_of
{ "id": "C0004936", "name": "mental disorders", "pos": [ 21, 37 ] }
{ "id": "C0005586", "name": "manic depressive", "pos": [ 162, 178 ] }
there was no significant difference between jugular and forearm blood in respect to either platelet-bound or free serotonin in the headache-free phase , and during migraine , the values for jugular and forearm blood were parallel .
nichd_parent_of
{ "id": "C0018681", "name": "headache", "pos": [ 131, 139 ] }
{ "id": "C0149931", "name": "migraine", "pos": [ 164, 172 ] }
there was a consistent increase in the maternal heart rate ( mhr ) and a significant rise in fetal heart rate ( fhr ) late in the infusion and in the postinfusion period .
nichd_parent_of
{ "id": "C0018810", "name": "heart", "pos": [ 48, 53 ] }
{ "id": "C0018811", "name": "fetal heart rate", "pos": [ 93, 109 ] }
when the preoperative work-up indicates that more than one procedure is indicated , we recommend that the total surgical treatment plan be carried through at one operation , although occasionally this approach may be contraindicated .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 59, 68 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 162, 171 ] }
on the basis of radiographic , transillumination , history , and clinical findings , the nine cysts that could be evaluated were diagnosed as being of the nonsecretory type of mucosal cyst .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 65, 82 ] }
{ "id": "C0011900", "name": "diagnosed", "pos": [ 129, 138 ] }
( 3 ) k1 strains are widely prevalent among infants , children , and adults and are quickly transmitted to infants .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 54, 62 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 107, 114 ] }
the clinical differentiation of hepatitis a from hepatitis b is often impossible , and only a finding of hepatitis b surface antigen in blood allows the presence of hepatitis b to be definitely diagnosed .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 94, 101 ] }
{ "id": "C0011900", "name": "diagnosed", "pos": [ 194, 203 ] }
it can be used to differentiate successfully a variety of diseases from osteomyelitis , and in conjunction with 67ga-citrate scan has become a mainstay in the work-up of the patient with infectious disease .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 58, 66 ] }
{ "id": "C0009450", "name": "infectious disease", "pos": [ 187, 205 ] }
the finding of positive lymphangiograms in 9 % of patients with stage b disease , 16 % of patients with stage c disease , and 57 % of patients with a fixation of the tumor to the pelvic or abdominal wall emphasizes the value of the procedure in limiting unnecessary surgical exploration .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 72, 79 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 166, 171 ] }
intestinal bypass is a reversible procedure which has been used with success in the surgical treatment of morbid obesity .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 34, 43 ] }
{ "id": "C0543467", "name": "surgical treatment", "pos": [ 84, 102 ] }
[ effect of disorder of the extra- and intraosseal blood supply of the mandible on the course of odontogenic infection under experimental conditions ] .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 12, 20 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 109, 118 ] }
with this set of variables the risk of coronary heart diseases can be estimated over a 30-fold range and 10 percent of the asymptomatic population identified in whom 25 percent of the coronary disease , 40 percent of the occlusive peripheral arterial disease and 50 percent of the strokes and congestive heart failure wi...
nichd_parent_of
{ "id": "C0018799", "name": "of the", "pos": [ 116, 122 ] }
{ "id": "C0018802", "name": "congestive heart failure", "pos": [ 293, 317 ] }
six months after returning to original homes there was no further growth in length or head circumference and a mean weight loss of 800 gm , thus declining to environmental norms .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 76, 82 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 86, 104 ] }
it is suggested that failure to consider an anaerobic cause in pulmonary infections , inappropriate specimens , transport and culture of anaerobic material , and the sensitivity of oral cavity-derived anaerobes to penicillin , serve to mask the true frequency of anaerobic lung infections in childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 292, 301 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 306, 317 ] }
subacute sclerosing panencephalitis ( sspe ) , a disease related to measles ( rubeola ) infection , was more common in arabs and sephardi jews than in ashkenazi jews in israel .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 49, 56 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 88, 97 ] }
the difference in birth weight between children with down 's syndrome and their siblings was estimated to be in the interval from .18 to .37 kg with 90 percent confidence , the down 's syndrome infants having the smaller mean birth weights .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 39, 47 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 194, 201 ] }
in searching for a possible cause of the uveitis in 6 patients having concurrent chronic iridocyclitis and chronic active hepatitis with serum australia antigen ( aa ) , the aqueous humor from each patient was analyzed for aa , passed through 220-mmu filters and inoculated directly into the livers of mice .
nichd_parent_of
{ "id": "C0042164", "name": "uveitis", "pos": [ 41, 48 ] }
{ "id": "C1510449", "name": "chronic iridocyclitis", "pos": [ 81, 102 ] }
the results suggest that the six positive aqueous specimens contained a viral infection agent , which may have been the core of the dane particle , and that the mouse is suitable for the laboratory investigation of type b hepatitis by the technique described .
nichd_parent_of
{ "id": "C0042769", "name": "viral infection", "pos": [ 72, 87 ] }
{ "id": "C0019163", "name": "b hepatitis", "pos": [ 220, 231 ] }
these results are interpreted as indicating a relatively less important role for immune complexes in the pathogenesis of erysipelothrix arthritis than is described for rheumatoid arthritis in persons .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 136, 145 ] }
{ "id": "C0003873", "name": "rheumatoid arthritis", "pos": [ 168, 188 ] }
our results demonstrated that mediastinal metastases occur commonly in patients with central lesions irrespective of cell type , but that the histologic tumor type has a definite influence on the frequency of mediastinal involvement in patients with parenchymal masses or peripheral lesions .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 153, 158 ] }
{ "id": "C0577559", "name": "masses", "pos": [ 262, 268 ] }
in a study of nonepithelial tumors involving the nasal cavity , paranasal sinuses , and nasopharynx , 19 lesions ( three rhabdomyomas , 16 rhabdomyosarcomas ) showed skeletal muscle differentiation .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 28, 34 ] }
{ "id": "C0035411", "name": "rhabdomyomas", "pos": [ 121, 133 ] }
such procedures have been demonstrated to be superior to evaluation via blood chemistry levels or routine skeletal radiographic surveys .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 5, 15 ] }
{ "id": "C0220825", "name": "evaluation", "pos": [ 57, 67 ] }
objective responses lasting more than 1 month occurred in 5 subjects with acute leukemias or lymphoma , 3 with transitional cell carcinomas , 2 with sarcomas , 2 with ewing 's sarcoma and 1 each with bronchogenic carcinoma , orchidoblastoma , and thymoma .
nichd_parent_of
{ "id": "C1261473", "name": "sarcomas", "pos": [ 149, 157 ] }
{ "id": "C0553580", "name": "ewing 's sarcoma", "pos": [ 167, 183 ] }
this procedure included ( a ) anesthesia for 1 to 1 1/2 hours before limb isolation , ( b ) 1/2 hour of denervation before isolation , and ( c ) perfusion after isolation for 1/2 hour at an arterial pressure of 100 mm hg and a venous pressure of 6 mm hg .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 5, 14 ] }
{ "id": "C0002903", "name": "anesthesia", "pos": [ 30, 40 ] }
these procedures have been evaluated and used to study the excretion of 3h-digoxin-12alpha and its metabolites in urines collected serially in 7 patients and in bile in one .
nichd_parent_of
{ "id": "C0184661", "name": "procedures", "pos": [ 6, 16 ] }
{ "id": "C0220825", "name": "evaluated", "pos": [ 27, 36 ] }
the use of the special ambulances markedly raised the severity of those cases of infarction admitted to hospital so that , despite appropriate therapeutic measures in the early phase , total mortaltiy of cases of myocardial infarction treated by ambulance and at hospital was 51.1 % .
nichd_parent_of
{ "id": "C0021308", "name": "infarction", "pos": [ 81, 91 ] }
{ "id": "C0027051", "name": "myocardial infarction", "pos": [ 213, 234 ] }
19 of the 24 hypoglycemic children were prematures or small for dates and it is postulated that the low glycogen stores in these infants do not meet the metabolic demands of the myocardium during its postpartum circulatory adaptation .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 26, 34 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 129, 136 ] }
the advantage of the procedure is the increased extent of the operation , the improved cosmetic result and the single stage of the procedure .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 21, 30 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 62, 71 ] }
indigenous organisms colonized the bases of papillae on the anterior tip and lateral edges of the tongue as discrete microcolonies , but bacteria were rarely observed on other papillae .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 11, 20 ] }
{ "id": "C0004611", "name": "bacteria", "pos": [ 137, 145 ] }
the initial number of cells which , after viral infection , developed into a condyloma acuminatum was estimated to be about 4,400 cells , on the basis of statistical analysis of the data in one case .
nichd_parent_of
{ "id": "C0042769", "name": "viral infection", "pos": [ 42, 57 ] }
{ "id": "C0009663", "name": "condyloma", "pos": [ 77, 86 ] }
in a clinical and roentgenographic study of spinal deformities in sixty-two patients in the later stages of duchenne muscular dystrophy , many patients had marked scoliosis and kyphosis , while others with hyperextended spines had comparatively little scoliosis .
nichd_parent_of
{ "id": "C0575157", "name": "spinal deformities", "pos": [ 44, 62 ] }
{ "id": "C0036439", "name": "scoliosis", "pos": [ 252, 261 ] }
a combination of two simple measures used in evaluation upon admission and relating to physical and mental functioning was found to predict the patient 's status at five months ( still in the hospital , dead , or discharged ) with 75 percent accuracy .
nichd_parent_of
{ "id": "C0220825", "name": "evaluation", "pos": [ 45, 55 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 87, 95 ] }
comparison of this large number of children with the few individuals in whom death occurs from chronic renal disease annually ( less than 0.03 % ) suggests that the vast majority of these children with urinary abnormalities have either no renal disease or at most a self-limited condition .
nichd_parent_of
{ "id": "C0027361", "name": "individuals", "pos": [ 57, 68 ] }
{ "id": "C0008059", "name": "children", "pos": [ 188, 196 ] }