text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
antisera were produced by the procedure which involved immunization with nka or nkb , both conjugated with keyhole limpet hemocyanin , and treatments with a tolerogenic conjugate of kassinin and a copolymer of d-glutamic acid and d-lysine ( d-gl ) to inhibit the production of cross-reactive antibodies against common c-terminal region of tachykinins . | nichd_parent_of | {
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} | {
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149
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} |
from 1979 to 1987 , 5 patients with cholecystocolonic fistula were operated on in our service , which represents 25 % of a total of 20 external biliodigestive fistulas complied over this period . | nichd_parent_of | {
"id": "C0016169",
"name": "fistula",
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54,
61
]
} | {
"id": "C0423772",
"name": "external",
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135,
143
]
} |
branhamella catarrhalis is a neisseriae-like organism that is the newest member of the family of pneumonic pathogens . | nichd_parent_of | {
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45,
53
]
} | {
"id": "C0450254",
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107,
116
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} |
until further information is known , bcg vaccinations should not be given to symptomatic hiv-infected individuals and should only be given to hiv-infected children who are asymptomatic and who reside in areas where tuberculosis is highly endemic and where the risk of tuberculosis may outweigh the potential complications of bcg immunization . | nichd_parent_of | {
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102,
113
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} | {
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"name": "children",
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155,
163
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} |
more rehospitalizations were independently related to a higher number of previous hospitalizations for heart disease , more pre-mi cardiac limitations , less cardiac lifestyle knowledge , and higher initial level of emotional distress . | nichd_parent_of | {
"id": "C0018799",
"name": "heart disease",
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103,
116
]
} | {
"id": "C0027051",
"name": "mi",
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141,
143
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} |
in 2 patients the finding of anti-ro antibodies led to the diagnosis of sjogren syndrome , which explained a succession of various autoimmune diseases , viz . glomerulonephritis , orbital lymphoma and hemolytic anemia in case 1 ; | nichd_parent_of | {
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25
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} | {
"id": "C0011900",
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the clinical signs of megaoesophagus , anorexia , constipation , dryness of all mucous membranes , reduced tear production , protrusion of the membrana nictitans , mydriasis , regurgitation and bradycardia are pathognomonic and ca n't be mistaken by any other disease . | nichd_parent_of | {
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"name": "clinical signs",
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4,
18
]
} | {
"id": "C0003123",
"name": "anorexia",
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39,
47
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} |
our experience with open reduction of calcaneus fractures and internal stabilization without joint transfixation ( n = 83 ) has shown us that the following features are mandatory in order to obtain normal postoperative foot statics and dynamics , normal joint mobility , and normal foot function : ( 1 ) restoration of the normal height , length and width of the calcaneus ; | nichd_parent_of | {
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156,
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} | {
"id": "C1444754",
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at present , the procedure for selection of patients for operation is still vague and random in denmark . | nichd_parent_of | {
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} |
in the rest of the cases the perpetrator was a relative , friend of the family or person known to the child . | nichd_parent_of | {
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"name": "person",
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82,
88
]
} | {
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"name": "child",
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} |
avoiding of recently introduced drugs , for which safety in pregnancy has not been adequately established , and using an inhaled route in preference to the oral route of administration are recommended . | nichd_parent_of | {
"id": "C0013153",
"name": "route",
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129,
134
]
} | {
"id": "C1527415",
"name": "oral",
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156,
160
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} |
the eswl group had significantly ( p less than 0.05 ) shorter duration of post-procedural pain , fewer requirements for pain medications , and decreased anxiety toward repetition of the procedure than did the sl group . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
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186,
195
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} | {
"id": "C0543467",
"name": "sl",
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209,
211
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} |
eighty-two patients were evaluated for erectile failure with a comprehensive history , physical examination , hormonal testing , noninvasive doppler examination ( pbi ) , and nocturnal penile tumescence ( npt ) . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
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25,
34
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} | {
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} |
because 42 percent of the patients with d1 disease in the mayo clinic experience have dna diploid tumors , adjuvant orchiectomy in this group results in no progression or prostate cancer death . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
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43,
50
]
} | {
"id": "C0027651",
"name": "tumors",
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98,
104
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} |
the early painful clinical signs simulating shock progressed with subnormal temperature , slow-shallow respiration and arrhythmic pulse followed by death due to respiratory failure within 96 to 120 hr . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
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18,
32
]
} | {
"id": "C0020672",
"name": "subnormal temperature",
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66,
87
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} |
the early painful clinical signs simulating shock progressed with subnormal temperature , slow-shallow respiration and arrhythmic pulse followed by death due to respiratory failure within 96 to 120 hr . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
18,
32
]
} | {
"id": "C0011065",
"name": "death",
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148,
153
]
} |
6 with mn associated with a hepatitis b virus ( hbv ) infection , 2 with idiopathic mn , and 1 with lupus nephritis . | nichd_parent_of | {
"id": "C0017665",
"name": "mn",
"pos": [
7,
9
]
} | {
"id": "C0086445",
"name": "idiopathic mn",
"pos": [
73,
86
]
} |
this leads to disorders of the menstrual cycle according to the type of hypomenstrual syndrome , polycystic degeneration of the ovaries and infertility . | nichd_parent_of | {
"id": "C0039082",
"name": "syndrome",
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86,
94
]
} | {
"id": "C0032460",
"name": "polycystic",
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97,
107
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} |
from the features obtained ( age , body weight , heredity , symptomatology , blood glucose and insulin concentrations basally and after 75 g ogtt ) subgroupings were worked out relevant for the therapy . | nichd_parent_of | {
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"name": "features",
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9,
17
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} | {
"id": "C0005910",
"name": "body weight",
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35,
46
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} |
aim of this investigation was to detect the importance of such finding for diagnosis and control of essential hypertension . | nichd_parent_of | {
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"name": "finding",
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63,
70
]
} | {
"id": "C0011900",
"name": "diagnosis",
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75,
84
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} |
in both these subjects the myoglobinuria was a secondary finding and not the cause of death . | nichd_parent_of | {
"id": "C0037088",
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57,
64
]
} | {
"id": "C0007465",
"name": "cause of death",
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} |
among 359 kidney transplantations performed from 1976 to 1986 at rostock the 4 most frequent original renal diseases were glomerulonephritis ( 280 x ) , pyelonephritis ( 74 x ) , diabetic nephropathy ( 22 x ) and polycystic kidney disease ( 14 x ) . | nichd_parent_of | {
"id": "C0022658",
"name": "renal diseases",
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102,
116
]
} | {
"id": "C0034186",
"name": "pyelonephritis",
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153,
167
]
} |
among 359 kidney transplantations performed from 1976 to 1986 at rostock the 4 most frequent original renal diseases were glomerulonephritis ( 280 x ) , pyelonephritis ( 74 x ) , diabetic nephropathy ( 22 x ) and polycystic kidney disease ( 14 x ) . | nichd_parent_of | {
"id": "C0022658",
"name": "renal diseases",
"pos": [
102,
116
]
} | {
"id": "C0022680",
"name": "polycystic kidney disease",
"pos": [
213,
238
]
} |
control and jaundiced rats did not differ with respect to clinical signs such as alertness , stance , hair coat , position of eyes , discharge from eyes and nose , and cleanliness of anal orifice . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
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58,
72
]
} | {
"id": "C0423006",
"name": "discharge from eyes",
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133,
152
]
} |
bacterial growth was expressed as colony-forming units per ml ( cfu/ml ) , reproducibility of the seeding procedure was checked , and the potential interference of h2s-producing bacteria with operation of the carbon dioxide/hydrogen systems was investigated . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
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106,
115
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} | {
"id": "C0543467",
"name": "operation",
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192,
201
]
} |
presently , in sciences three phenomena are thought of as being important in malignant diseases : the immunologic condition of the organism , the role of the virus as an etiologic factor , and the intracellular derangements . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
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131,
139
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} | {
"id": "C0042776",
"name": "virus",
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158,
163
]
} |
oogs , characterized by exophthalmos , chemosis and orbital masses , was observed in 33 ( 27.2 % ) of 121 aml patients compared with 41 children of amml without ophthalmic tumors during the same period . | nichd_parent_of | {
"id": "C0023467",
"name": "aml",
"pos": [
106,
109
]
} | {
"id": "C0023479",
"name": "amml",
"pos": [
148,
152
]
} |
it is generally considered that the presence of chemicals in the environment including carcinogens and modifiers ( promoters , inhibitors , anti-promoters , etc . ) is responsible for the geographical variation in human neoplasia including urinary bladder cancer development . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasia",
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220,
229
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
256,
262
]
} |
the presence of neoplastic clear cells is characteristic of peripheral t-cell malignancies , and is likely to be found in cd4+ lymphomas . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
78,
90
]
} | {
"id": "C0024299",
"name": "lymphomas",
"pos": [
127,
136
]
} |
in perinatal at-risk infants ( n = 11 ) , premature infants ( n = 6 ) and term infants ( n = 5 ) ultrasound is a reliable diagnostic method in the detection and follow-up of intraventricular hemorrhage and perivascular leukomalacia in preterm infants , while for the diagnosis of hypoxic-ischemic lesions , especially focal cortico-subcortical changes in term infants , besides ultrasound it is necessary to perform ct . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic method",
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122,
139
]
} | {
"id": "C0041618",
"name": "ultrasound",
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378,
388
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} |
the results obtained with current diagnostic methods such as ultrasound and computed tomography are evaluated , and the personal experience in preoperative cytological diagnosis is updated . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic methods",
"pos": [
34,
52
]
} | {
"id": "C0041618",
"name": "ultrasound",
"pos": [
61,
71
]
} |
in spain , its presentation is rare , corresponding to 10.42 % of all tumors and 0.7 % of all malignant tumors of the male . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
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70,
76
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
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110
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} |
therefore , we treated a group of thrombocythemic patients with ph-negative myeloproliferative disorders , including polycythemia vera and essential thrombocythemia , with recombinant interferon-alpha ( rifn-alpha 2a ) . | nichd_parent_of | {
"id": "C0836924",
"name": "thrombocythemic",
"pos": [
34,
49
]
} | {
"id": "C0040028",
"name": "essential thrombocythemia",
"pos": [
139,
164
]
} |
in this communication attention is called to some features of ovarian cyst formation in rats after exposure to 6 mg/100 gm body weight of dehydroepiandrosterone for 21 days . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
50,
58
]
} | {
"id": "C0005910",
"name": "weight",
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128,
134
]
} |
it was the aim of this study to evaluate incidence and criterias of postanaesthetic hypoxygenation following balanced anaesthesia with isoflurane and to estimate both the actually most valid parameter ( pso2 ) and the monitoring of choice ( pulse oximetry ) . | nichd_parent_of | {
"id": "C0523807",
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"pos": [
203,
207
]
} | {
"id": "C0034108",
"name": "pulse oximetry",
"pos": [
241,
255
]
} |
although open lung biopsy ( olb ) is frequently employed for diagnosis of pulmonary lesions in patients with hodgkin 's disease , the actual efficacy of the procedure in establishing a diagnosis in these patients , and its effect on their treatment and clinical outcome , have not been evaluated . | nichd_parent_of | {
"id": "C0184661",
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157,
166
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} | {
"id": "C0220825",
"name": "evaluated",
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286,
295
]
} |
main results : compared with a gastrointestinal disease control group ( 0.5 % +/- 0.8 % ) , specific lysis against ecac-c ( colon-derived ) among patients with inflammatory bowel disease was significantly greater in both multiply affected ( 8.4 % +/- 8.2 % ; p less than 0.01 ) and singly affected ( 5.2 % +/- 5.4 % ; p less than 0.05 ) families . | nichd_parent_of | {
"id": "C0017178",
"name": "gastrointestinal disease",
"pos": [
31,
55
]
} | {
"id": "C0021390",
"name": "inflammatory bowel disease",
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160,
186
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} |
the tumor always has a benign character in the case of pure hemangioma , therefore the results are generally satisfactory . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
4,
9
]
} | {
"id": "C0018916",
"name": "benign",
"pos": [
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} |
of the primary gn , minor abnormalities was the most common ( 22 % ) , followed by focal global sclerosis ( 20 % ) , focal segmental glomerulosclerosis ( 17 % ) , diffuse mesangial proliferative gn ( 11 % ) , focal mesangial proliferative gn ( 9 % ) , membranous gn ( 7 % ) , diffuse endocapillary gn ( 4 % ) , diffuse sclerosing gn ( 4 % ) , diffuse mesangial sclerosis ( 4 % ) , and diffuse crescentic gn ( 2 % ) . | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
15,
17
]
} | {
"id": "C0221238",
"name": "mesangial proliferative gn",
"pos": [
215,
241
]
} |
of the primary gn , minor abnormalities was the most common ( 22 % ) , followed by focal global sclerosis ( 20 % ) , focal segmental glomerulosclerosis ( 17 % ) , diffuse mesangial proliferative gn ( 11 % ) , focal mesangial proliferative gn ( 9 % ) , membranous gn ( 7 % ) , diffuse endocapillary gn ( 4 % ) , diffuse sclerosing gn ( 4 % ) , diffuse mesangial sclerosis ( 4 % ) , and diffuse crescentic gn ( 2 % ) . | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
15,
17
]
} | {
"id": "C0017665",
"name": "membranous gn",
"pos": [
252,
265
]
} |
of the primary gn , minor abnormalities was the most common ( 22 % ) , followed by focal global sclerosis ( 20 % ) , focal segmental glomerulosclerosis ( 17 % ) , diffuse mesangial proliferative gn ( 11 % ) , focal mesangial proliferative gn ( 9 % ) , membranous gn ( 7 % ) , diffuse endocapillary gn ( 4 % ) , diffuse sclerosing gn ( 4 % ) , diffuse mesangial sclerosis ( 4 % ) , and diffuse crescentic gn ( 2 % ) . | nichd_parent_of | {
"id": "C0017658",
"name": "gn",
"pos": [
15,
17
]
} | {
"id": "C0403416",
"name": "crescentic gn",
"pos": [
393,
406
]
} |
the prognosis is not significantly less in bilateral as compared in unilateral disease provided that 3 or less tumours , no extrahepatic spread at the tumour free margin more than 10 mm can be achieved . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
79,
86
]
} | {
"id": "C0027651",
"name": "tumour",
"pos": [
151,
157
]
} |
relatives of children in the nonaffective psychiatric control ( pc ) group had low rates of alcoholism , high rates of other ( anxiety ) disorder diagnoses , and intermediate rates of mdd ( accounted for by those children with separation anxiety ) . | nichd_parent_of | {
"id": "C0003469",
"name": "anxiety",
"pos": [
127,
134
]
} | {
"id": "C0003477",
"name": "separation anxiety",
"pos": [
227,
245
]
} |
a trend was evident that patients with poor histologic grade , or those with dukes ' b and c tumors that were aneuploid fared worse than those with diploid cancers . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
93,
99
]
} | {
"id": "C0006826",
"name": "cancers",
"pos": [
156,
163
]
} |
reduction in platelet-binding immunoglobulins and improvement in platelet counts in patients with hiv-associated idiopathic thrombocytopenia purpura ( itp ) following extracorporeal immunoadsorption of plasma over staphylococcal protein a-silica . | nichd_parent_of | {
"id": "C0392386",
"name": "reduction",
"pos": [
0,
9
]
} | {
"id": "C0398650",
"name": "idiopathic thrombocytopenia purpura",
"pos": [
113,
148
]
} |
although further investigation is needed , our preliminary study suggests that myocardial scanning with thallium can be a safe , fairly rapid , and useful objective parameter in the emergency department detection of suspected myocardial infarction , and in differential diagnosis of chest pain when other data such as the history , physical examination , ecg , or enzymes are inconclusive . | nichd_parent_of | {
"id": "C0220825",
"name": "investigation",
"pos": [
17,
30
]
} | {
"id": "C0031809",
"name": "physical examination",
"pos": [
332,
352
]
} |
in evaluating the outcome of pregnancies in patients not at high risk for preterm delivery ( ordinary risk patients ) we found that patients who received instruction to recognize early signs of preterm labor had babies with a higher birthweight ( 3255 +/- 548 gm ) than patients who were not so instructed ( 3200 +/- 599 gm , p = 0.03 ) . | nichd_parent_of | {
"id": "C0032972",
"name": "outcome of pregnancies",
"pos": [
18,
40
]
} | {
"id": "C0151526",
"name": "preterm",
"pos": [
194,
201
]
} |
the most effective actual diagnostic methods include ultrasonography , cat scan , and basic laboratory data , which can corroborate the clinical diagnosis of cchc with 100 % certainty . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic methods",
"pos": [
26,
44
]
} | {
"id": "C0041618",
"name": "ultrasonography",
"pos": [
53,
68
]
} |
the surgical treatment of cchc is controversial , but the surgical procedures of choice are choledochocystojejunostomy with total cyst removal , roux 's y , and cholecystectomy . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical",
"pos": [
4,
12
]
} | {
"id": "C0015250",
"name": "total",
"pos": [
124,
129
]
} |
serological surveys for antibodies , suggest that approximately 5.98 % of people had intestinal mucosal or liver invasion , but amebic dysentery may be five to 50 times more frequent than liver abscess , namely in children . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
74,
80
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
214,
222
]
} |
we examined ssep in children with various neurological disorders and found that ssep was useful for evaluating sensory functions and somatosensory damages in children who were unable to cooperate in clinical examinations . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluating",
"pos": [
100,
110
]
} | {
"id": "C0031809",
"name": "clinical examinations",
"pos": [
199,
220
]
} |
pregnancy outcomes considered were preterm delivery , low birthweight , low birthweight for gestational age , and perinatal death . | nichd_parent_of | {
"id": "C0032972",
"name": "pregnancy outcomes",
"pos": [
0,
18
]
} | {
"id": "C0151526",
"name": "preterm delivery",
"pos": [
35,
51
]
} |
pregnancy outcomes considered were preterm delivery , low birthweight , low birthweight for gestational age , and perinatal death . | nichd_parent_of | {
"id": "C0032972",
"name": "pregnancy outcomes",
"pos": [
0,
18
]
} | {
"id": "C0701826",
"name": "perinatal death",
"pos": [
114,
129
]
} |
the findings suggest that observed class differences in pregnancy outcome are attributable to the mother 's personal characteristics ( height/weight , parity ) and her lifestyle . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
117,
132
]
} | {
"id": "C0030563",
"name": "parity",
"pos": [
151,
157
]
} |
delivery in the chair conferred no benefits to mother or baby and resulted in greater mean blood loss and a higher rate of postpartum haemorrhage . | nichd_parent_of | {
"id": "C0019080",
"name": "blood loss",
"pos": [
91,
101
]
} | {
"id": "C0032797",
"name": "postpartum haemorrhage",
"pos": [
123,
145
]
} |
assessment of anatomical abnormalities by severity of dr on colour photographs correlated well with the functional abnormalities of the blood-retinal barrier ( s ) assessed by vf , especially for the macular field . | nichd_parent_of | {
"id": "C0302142",
"name": "anatomical abnormalities",
"pos": [
14,
38
]
} | {
"id": "C0000768",
"name": "abnormalities",
"pos": [
115,
128
]
} |
a clinical use in 15 burned patients was shown that in combination with enzymatic and antimicrobial drug solutions these materials accelerate healing and epithelialization of superficial burn wounds and improve treatment of deep burn wounds before autodermoplasty . | nichd_parent_of | {
"id": "C0006434",
"name": "burned",
"pos": [
21,
27
]
} | {
"id": "C0332686",
"name": "superficial burn wounds",
"pos": [
175,
198
]
} |
among patients with anl and all transplanted in relapse , the probability of relapse after day 150 was 74 % without [ corrected ] gvhd , 45 % with acute and chronic gvhd , 35 % with [ corrected ] only acute gvhd , and 34 % with only chronic gvhd ( p less than .001 ) . | nichd_parent_of | {
"id": "C0018133",
"name": "gvhd",
"pos": [
130,
134
]
} | {
"id": "C0856825",
"name": "acute gvhd",
"pos": [
201,
211
]
} |
among patients with anl and all transplanted in relapse , the probability of relapse after day 150 was 74 % without [ corrected ] gvhd , 45 % with acute and chronic gvhd , 35 % with [ corrected ] only acute gvhd , and 34 % with only chronic gvhd ( p less than .001 ) . | nichd_parent_of | {
"id": "C0018133",
"name": "gvhd",
"pos": [
130,
134
]
} | {
"id": "C0867389",
"name": "chronic gvhd",
"pos": [
233,
245
]
} |
among patients with cml in acceleration or blast crisis , the probability of relapse after day 150 was 65 % without gvhd and 36 % with acute and/or chronic gvhd ( p less than .017 ) . | nichd_parent_of | {
"id": "C0018133",
"name": "gvhd",
"pos": [
116,
120
]
} | {
"id": "C0867389",
"name": "chronic gvhd",
"pos": [
148,
160
]
} |
our results show that even after myeloablative therapy for bone marrow transplantation bcr-abl mrnas are still expressed . | nichd_parent_of | {
"id": "C0087111",
"name": "therapy",
"pos": [
47,
54
]
} | {
"id": "C0005961",
"name": "bone marrow transplantation",
"pos": [
59,
86
]
} |
during therapy , six out of eight cases showed a decrease in tumour t1 , five responding to therapy and one with stationary disease , while the two patients with progressive disease showed unchanged tumour t1 . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
124,
131
]
} | {
"id": "C0027651",
"name": "tumour",
"pos": [
199,
205
]
} |
the possibility that the inhibition of the generation of leukotriene compounds might have a significant effect in limiting a variety of inflammatory disorders was suggested by the extensive pro-inflammatory effects demonstrated by these substances , the demonstration that many inflammatory cells generate leukotrienes , and the finding that the leukotrienes can be detected in complex biological fluids in vivo . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
237,
247
]
} | {
"id": "C0005889",
"name": "fluids",
"pos": [
397,
403
]
} |
the individual vaccine components from the polyvalent vaccines when inoculated alone did not significantly suppress the lymphocyte response to mitogen . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
15,
22
]
} | {
"id": "C1514218",
"name": "polyvalent vaccines",
"pos": [
43,
62
]
} |
the main indications of pars plana vitrectomy are opacities of the vitreous without tendency to be absorbed , proliferating retinopathies , complicated retina detachment , heavy ocular injuries and states after the injuries , infective endopthalmitis and epimacular membranes . | nichd_parent_of | {
"id": "C0035309",
"name": "retinopathies",
"pos": [
124,
137
]
} | {
"id": "C0035305",
"name": "retina",
"pos": [
152,
158
]
} |
in vitro data indicate both qualitative and quantitative differences in faa protein binding : approximately 80 % is bound in humans , with two different types of binding site identified ; | nichd_parent_of | {
"id": "C0205556",
"name": "qualitative",
"pos": [
28,
39
]
} | {
"id": "C0205396",
"name": "identified",
"pos": [
175,
185
]
} |
impedance to venous return by distention of a balloon in the inferior vena cava ( ivcb ) was utilized in 10 patients , during diagnostic procedures , to reduce blood flow through the lungs at baseline and to buffer its changes during stimulation of the adrenergic system , which was obtained with mental arithmetic ( at ) and cold pressor ( cpt ) tests . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic procedures",
"pos": [
126,
147
]
} | {
"id": "C0022885",
"name": "tests",
"pos": [
347,
352
]
} |
adverse effects associated with octreotide therapy generally have been mild , including pain or burning at the injection site , abdominal pain , and diarrhea . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
88,
92
]
} | {
"id": "C0000737",
"name": "abdominal pain",
"pos": [
128,
142
]
} |
anti-sympathetic ganglia antibodies and postural blood pressure in iddm subjects of varying duration and patients at high risk of developing iddm . | nichd_parent_of | {
"id": "C0011849",
"name": "iddm",
"pos": [
67,
71
]
} | {
"id": "C0011854",
"name": "iddm",
"pos": [
141,
145
]
} |
the 457 study children , 6 , 10 and 16 years of age , had as infants received routine primary vaccination with three doses of diphtheria-tetanus-toxoid or diphtheria-tetanus-pertussis vaccine , and the 16 year-olds also had received a booster dose of tetanus with a small dose of diphtheria at the age of ten . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
14,
22
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
61,
68
]
} |
three diverse groups of fungi are responsible for these infections : the agents of phaeohyphomycosis and hyalohyphomycosis and certain yeasts . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
24,
29
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
135,
141
]
} |
cases in which there are multiple tumors are often bilateral , and this finding may create diagnostic confusion . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
72,
79
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
91,
101
]
} |
measurements were taken on body weight , muscle weight and four kind of skeletal characteristics ( skeletal weight , skeletal length , skeletal width and skeletal height ) . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
81,
96
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
108,
114
]
} |
measurements were taken on body weight , muscle weight and four kind of skeletal characteristics ( skeletal weight , skeletal length , skeletal width and skeletal height ) . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
81,
96
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
126,
132
]
} |
having a newborn child admitted to a newborn intensive care unit can be a traumatic experience for parents ; | nichd_parent_of | {
"id": "C0008059",
"name": "child",
"pos": [
17,
22
]
} | {
"id": "C0021289",
"name": "newborn",
"pos": [
37,
44
]
} |
the precise genomic site is of interest since the region 12q13-15 has been found to be consistently rearranged in neoplasia-associated chromosome abnormalities in lipomas , myxoid liposarcomas , uterine leiomyomas , and pleomorphic adenomas of the salivary gland . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
114,
123
]
} | {
"id": "C0023798",
"name": "lipomas",
"pos": [
163,
170
]
} |
effects of cyclosporin a on progressive and regressive tumors induced by two cancer lines derived from a single colon carcinoma chemically induced in the rat . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
55,
61
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
77,
83
]
} |
the frequent expression of tag-72 in actively inflamed colonic mucosa ( ulcerative colitis and other colitides ) may limit the clinical utility of this antigen for detecting colon cancer in ulcerative colitis patients by serological assay or in vivo radiolocalization techniques . | nichd_parent_of | {
"id": "C0009319",
"name": "colitides",
"pos": [
101,
110
]
} | {
"id": "C0009324",
"name": "ulcerative colitis",
"pos": [
190,
208
]
} |
candida infections are the bell-wether of progression to symptomatic hiv infection and candida oesophagitis often marks the onset of the acquired immunodeficiency syndrome ( aids ) . | nichd_parent_of | {
"id": "C0006840",
"name": "candida",
"pos": [
0,
7
]
} | {
"id": "C0239295",
"name": "candida oesophagitis",
"pos": [
87,
107
]
} |
they are considered responsible for a range of diseases in aids patients including retinitis , gastrointestinal disease , pneumonitis and , less frequently , encephalitis . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
47,
55
]
} | {
"id": "C0017178",
"name": "gastrointestinal disease",
"pos": [
95,
119
]
} |
other tumors of the nervous system evaluated included 9 medulloblastomas ( mean 17.9 % , range 5.0 % -42.0 % ) , 17 benign meningiomas ( mean 1.1 % , range 0 % -5 % ) , 15 metastatic carcinomas ( mean 16.5 % , range less than 1 % -46.0 % ) , and individual tumors of various types . | nichd_parent_of | {
"id": "C0027766",
"name": "tumors of the nervous system",
"pos": [
6,
34
]
} | {
"id": "C0025149",
"name": "medulloblastomas",
"pos": [
56,
72
]
} |
accurate quantitation of local glucose metabolic rates ( lmrglc ) of abnormal tissues such as brain tumors with the 2-deoxyglucose ( dg ) method requires knowledge of the tissue rate constants and lumped constant . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
100,
106
]
} | {
"id": "C0577559",
"name": "lumped",
"pos": [
197,
203
]
} |
the lesions are often refractory to conservative topical and surgical therapy and frequently require circumcision as a curative measure . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical",
"pos": [
61,
69
]
} | {
"id": "C0008819",
"name": "circumcision",
"pos": [
101,
113
]
} |
in this study we investigated developmental changes in the auditory p3 latency from childhood to adolescence . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
84,
93
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
97,
108
]
} |
pz : 19.27 msec/yr ) from childhood to adolescence , suggesting an increased efficiency in processing information as children mature . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
26,
35
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
39,
50
]
} |
when viewed within the context of an antigenic system that possesses widely diverse idiotypy , continued introduction of polyclonal anti-id appears eventually to : 1 ) induce polyclonal ab3 with quantitative expression of idiotypically related antibodies in preference to ab3 of ancestral ( 9-40 ) antigenic specificity , 2 ) relative to ab1 , induce a 100-fold increase in the level of ab3 antibodies that have both ancestral idiotype and ancestral antigen reactivity , and 3 ) induce polyclonal ab3 antibodies with a measurably wider range of antigenic reactivities than those of polyclonal ab1 . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
195,
207
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
536,
541
]
} |
the complexities in the nature and classification of pigment cell tumors in fish will be discussed on the basis of a survey of our collection of these tumors at the cancer institute . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
66,
72
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
165,
171
]
} |
organisms commonly regarded as pathogens were present in 25 samples ( haemophilus influenzae 17 , streptococcus pneumoniae four , other streptococci four ) . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
0,
9
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
31,
40
]
} |
pentoxifylline given in patients with vascular disease or in those with high risk of thrombosis ( diabetes , arteritis ) induces a significant decrease in plasma fibrinogen level . | nichd_parent_of | {
"id": "C0042373",
"name": "vascular disease",
"pos": [
38,
54
]
} | {
"id": "C0040053",
"name": "thrombosis",
"pos": [
85,
95
]
} |
pentoxifylline given in patients with vascular disease or in those with high risk of thrombosis ( diabetes , arteritis ) induces a significant decrease in plasma fibrinogen level . | nichd_parent_of | {
"id": "C0042373",
"name": "vascular disease",
"pos": [
38,
54
]
} | {
"id": "C0003860",
"name": "arteritis",
"pos": [
109,
118
]
} |
interaction of mbp with these organisms results in attachment , uptake , and killing of the opsonized bacteria by phagocytes . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
30,
39
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
102,
110
]
} |
a variant of cystatin c lacking the first nh2-terminal residues and having one amino acid substitution at position 68 forms amyloid deposits mainly in the walls of brain arteries , causing fatal strokes in icelandic patients with familial cerebral hemorrhage secondary to a form of an autosomal dominant amyloidosis . | nichd_parent_of | {
"id": "C0038454",
"name": "strokes",
"pos": [
195,
202
]
} | {
"id": "C2937358",
"name": "cerebral hemorrhage",
"pos": [
239,
258
]
} |
in summary , as a means of providing long-term disease-free survival and possible cure , bmt should be considered for children with all presenting poor-prognostic features , particularly certain chromosomal translocations [ t ( 4 ; 11 ) , t ( 9 ; 22 ) ] , very high wbc counts , notably if associated with a non-t immunophenotype , and , perhaps , a poor response to initial therapy with corticosteroids ( cs ) , or infants less than 6 months of age . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
118,
126
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
416,
423
]
} |
allelic frequencies and haplotypic variants for cystic fibrosis chromosomes with respect to dna markers closely linked to the cystic fibrosis locus were similar in families with cystic fibrosis with meconium ileus and those with no meconium ileus . | nichd_parent_of | {
"id": "C0010674",
"name": "cystic fibrosis",
"pos": [
48,
63
]
} | {
"id": "C0546982",
"name": "with cystic fibrosis",
"pos": [
173,
193
]
} |
in predicting response to therapy , poor prognostic factors included large tumor burdens , advanced disease stage , and chemotherapy-resistant tumors . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
100,
107
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
143,
149
]
} |
serum samples from eight dogs with primary hyperparathyroidism , seven dogs with hypercalcemic lymphosarcoma ( hypercalcemia of malignancy ) , and four dogs with primary hypoparathyroidism were submitted to the animal health diagnostic laboratory at michigan state university for intact parathyroid hormone ( pth ) assay . | nichd_parent_of | {
"id": "C0020437",
"name": "hypercalcemic",
"pos": [
81,
94
]
} | {
"id": "C0149911",
"name": "hypercalcemia of malignancy",
"pos": [
111,
138
]
} |
visual analogue scales as a measure of pain in arthritis : a study of overall pain and pain in individual joints at rest and on movement . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
39,
43
]
} | {
"id": "C0003862",
"name": "pain in",
"pos": [
87,
94
]
} |
visual analogue scales ( vas ) for overall and individual joint pain at rest and on movement were completed by 105 patients with polyarthritis as part of a study of the relationship between overall pain and pain in individual joints . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
64,
68
]
} | {
"id": "C0003862",
"name": "pain in",
"pos": [
207,
214
]
} |
the quality of pain in arthritis : the words patients use to describe overall pain and pain in individual joints at rest and on movement . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
15,
19
]
} | {
"id": "C0003862",
"name": "pain in",
"pos": [
87,
94
]
} |
there is great potential for preventive medicine , but a major immediate benefit is the newfound ability to exclude the carrier state in many people at risk and to protect fetuses from abortion when , as in most cases , they are shown to be normal by dna tests . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
142,
148
]
} | {
"id": "C0015965",
"name": "fetuses",
"pos": [
172,
179
]
} |
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