text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
when clinical findings or laboratory findings were either positive or equivocal , then scanning techniques were used . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
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} | {
"id": "C0587081",
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while other anxiety disorders have recently become the subjects of increasing investigation , social phobia remains , except among behavior therapists , relatively unstudied . | nichd_parent_of | {
"id": "C0003469",
"name": "anxiety disorders",
"pos": [
12,
29
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} | {
"id": "C0031572",
"name": "social phobia",
"pos": [
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107
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} |
existing findings do suggest that in its own right and as a comparison for other anxiety disorders , social phobia should prove a fertile area for psychobiological and clinical investigation . | nichd_parent_of | {
"id": "C0003469",
"name": "anxiety disorders",
"pos": [
81,
98
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} | {
"id": "C0031572",
"name": "social phobia",
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however , mere phagocytosis of virus particles into cell lysosomes , which occurred when trypsin-untreated virus was used , does not appear to be related to rotavirus replication . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
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} | {
"id": "C0035870",
"name": "rotavirus",
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157,
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elisa igm assay for cysticercosis was negative in all csf samples of control groups and it was positive in 12 of the 26 csf samples of the neurocysticercosis group ( 46.2 % ) . | nichd_parent_of | {
"id": "C0010678",
"name": "cysticercosis",
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20,
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} | {
"id": "C0338437",
"name": "neurocysticercosis",
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139,
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p. falciparum malaria was cultured in vitro in the presence of sera from patients with cerebral malaria , meningitis and also after chloroquine administration . | nichd_parent_of | {
"id": "C0024530",
"name": "malaria",
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14,
21
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} | {
"id": "C0024534",
"name": "cerebral malaria",
"pos": [
87,
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recent work suggests that a standard model often used for projection of risk forward in time , the constant relative excess model , may give a surprisingly accurate picture of time to tumor for a number of cancer sites . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
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184,
189
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} | {
"id": "C0006826",
"name": "cancer",
"pos": [
206,
212
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these data confirm that pulmonary function abnormalities are common in patients with systemic sclerosis including crest syndrome . | nichd_parent_of | {
"id": "C0036421",
"name": "systemic sclerosis",
"pos": [
85,
103
]
} | {
"id": "C0206138",
"name": "crest syndrome",
"pos": [
114,
128
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} |
an enzyme-linked immunosorbent assay ( elisa ) to measure mi-2 antibody , using this antigen , was used to test the sera of 139 myositis patients : 52 had dm and 87 had pm . | nichd_parent_of | {
"id": "C0027121",
"name": "myositis",
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128,
136
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} | {
"id": "C0085655",
"name": "pm",
"pos": [
169,
171
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} |
valve prolapse in these cases may have resulted from structural and functional derangement caused by the underlying non-specific vasculitis that occurs in behcet 's disease . | nichd_parent_of | {
"id": "C0042384",
"name": "vasculitis",
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129,
139
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} | {
"id": "C0004943",
"name": "behcet 's disease",
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155,
172
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} |
the test procedure was sufficiently simple and well tolerated to be included in our routine electrophysiological investigation . | nichd_parent_of | {
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} | {
"id": "C0220825",
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the characteristic relaxation time is voltage dependent and temperature dependent ( q10 approximately equal to 3 ) suggesting that the fluctuations arise from conformational fluctuations in the channel protein . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
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4,
18
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} | {
"id": "C0039476",
"name": "temperature",
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71
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} |
antigen expressed on blast cells of patients with amonol , on those in part of patients with aml and amml , on leukocytes of patients with chronic ml , on monocytes of a patient with chronic monol . | nichd_parent_of | {
"id": "C0023467",
"name": "aml",
"pos": [
93,
96
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} | {
"id": "C0023479",
"name": "amml",
"pos": [
101,
105
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} |
marked inhibition of cytotoxicity and ability for interferon activation was detected in nk isolated from tumors ( as compared with blood ) , with that inhibition being far more pronounced in highly malignant hetr-mln-8 tumors . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
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111
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} | {
"id": "C0006826",
"name": "malignant",
"pos": [
198,
207
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} |
blood smears stained with wright-giemsa were obtained from 124 patients with pathologically confirmed cutaneous t cell lymphoma ( ctcl ) , 70 patients with various other cutaneous disorders , and ten healthy adult volunteers . | nichd_parent_of | {
"id": "C0037274",
"name": "cutaneous disorders",
"pos": [
170,
189
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} | {
"id": "C0014518",
"name": "ten",
"pos": [
196,
199
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} |
we compared growth of t ( 4 ; 11 ) leukemia to typical acute nonlymphocytic leukemia ( anl ) and acute lymphocytic leukemia ( all ) . | nichd_parent_of | {
"id": "C0023418",
"name": "typical",
"pos": [
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54
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} | {
"id": "C0023449",
"name": "acute lymphocytic leukemia",
"pos": [
97,
123
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} |
we have carried out technetium-99 pertechnetate joint scans in the elbows , knees and ankles of 23 haemophilic patients and compared the isotope uptake of the 15 patients with clinical and radiological evidence of arthritis to that of eight patients without arthritis , to 13 age-matched healthy male controls , and to 10 age-matched males with active rheumatoid arthritis . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
214,
223
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
352,
372
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} |
isotope uptake into the knee joints was significantly higher in haemophilic arthritis than in controls , haemophiliacs without arthritis , and patients with rheumatoid arthritis [ median percentage uptake of administered technetium ( tc ) dose x 10 ( 3 ) in right knee = 9.4 , 6.2 , 6.4 and 6.6 , respectively ] : and the differences from haemophilic arthritis were all significant ( p less than 0.01 , mann-whitney u test ) . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
76,
85
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} | {
"id": "C0003873",
"name": "rheumatoid",
"pos": [
157,
167
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} |
parity is a determinant of patterns of disease in working women , and the relative excess of cancer of the breast , ovary , and uterine body in professional and clerical workers probably reflected the high proportion of nulliparous women in these groups . | nichd_parent_of | {
"id": "C0030563",
"name": "parity",
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6
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} | {
"id": "C0425979",
"name": "nulliparous",
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220,
231
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} |
in addition , this final rule specifies the procedures we follow in reducing the level of federal financial participation in state administrative expenditures if a state fails to meet the conditions for initial operation , initial approval , or reapproval of an mmis . | nichd_parent_of | {
"id": "C0184661",
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54
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} | {
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211,
220
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} |
pathology reports of over 580 male patients with germ cell tumors treated between 1972 and 1982 were screened for teratomas in which malignant transformation was apparent . | nichd_parent_of | {
"id": "C0205851",
"name": "germ cell tumors",
"pos": [
49,
65
]
} | {
"id": "C0039538",
"name": "teratomas",
"pos": [
114,
123
]
} |
in four cancer patient groups ( lymphoma , sarcoma , osteosarcoma and metastatic sarcoma ) with no or minimal weight loss , most plasma amino acid levels were similar to controls . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
43,
50
]
} | {
"id": "C0029463",
"name": "osteosarcoma",
"pos": [
53,
65
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} |
in 75 ( 27 % ) the tumor foci beyond 2 cm were histologically noninvasive cancers , and in 46 cases ( 16 % ) they contained invasive cancers as well . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
19,
24
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} | {
"id": "C0006826",
"name": "cancers",
"pos": [
133,
140
]
} |
the availability of primate species infected with the serologically related stlv-iii agents that either resist disease development ( african green monkeys ) or succumb to an aids-type syndrome ( rhesus ) provide models that should aid in our attempts to develop such vaccines . | nichd_parent_of | {
"id": "C0012634",
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118
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} | {
"id": "C0039082",
"name": "syndrome",
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184,
192
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} |
acquired immunodeficiency syndrome ( aids ) is a pandemic immunosuppressive disease that predisposes to life-threatening opportunistic infections and unusual forms of neoplasms . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
76,
83
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} | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
167,
176
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} |
the spectrum of infection ranges from an asymptomatic but apparently contagious carrier state to severe immunodeficiency with opportunistic infections and neoplasms . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
16,
25
]
} | {
"id": "C0029118",
"name": "opportunistic infections",
"pos": [
126,
150
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} |
group 0 has no evident disease ( 9 patients ) , group 1 has lymphadenopathy with or without exaggerated infection ( 16 patients ) , group 2 has persistent lymphadenopathy with chronic hepatitis b surface antigenemia or profound hypergammaglobulinemia ( 7 patients ) , group 3 has oral candidiasis with or without lymphadenopathy ( 7 patients ) . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
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23,
30
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} | {
"id": "C0009450",
"name": "infection",
"pos": [
104,
113
]
} |
group 0 has no evident disease ( 9 patients ) , group 1 has lymphadenopathy with or without exaggerated infection ( 16 patients ) , group 2 has persistent lymphadenopathy with chronic hepatitis b surface antigenemia or profound hypergammaglobulinemia ( 7 patients ) , group 3 has oral candidiasis with or without lymphadenopathy ( 7 patients ) . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
104,
113
]
} | {
"id": "C0006849",
"name": "oral",
"pos": [
280,
284
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} |
treatment of refractory hodgkin 's disease with teniposide , cisplatin , hexamethylmelamine , and prednisolone : cancer and leukemia group b trial 8171 . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
113,
119
]
} | {
"id": "C0023418",
"name": "group",
"pos": [
133,
138
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} |
remission was achieved in 13 of 80 evaluable patients with acute myeloid leukemia , in one of 12 evaluable patients with acute lymphoid leukemia , and in none of 11 patients with blastic transformation of chronic granulocytic leukemia . | nichd_parent_of | {
"id": "C0023467",
"name": "acute myeloid leukemia",
"pos": [
59,
81
]
} | {
"id": "C0023479",
"name": "blastic",
"pos": [
179,
186
]
} |
we studied the effect of deoxyguanosine ( dguo ) on cellular cytarabine ( ara-c ) nucleotide accumulation of the human leukemia cell line k562 and of bone marrow blast cells derived from patients with acute nonlymphocytic leukemia . | nichd_parent_of | {
"id": "C0023418",
"name": "k562",
"pos": [
138,
142
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} | {
"id": "C0023467",
"name": "acute nonlymphocytic leukemia",
"pos": [
201,
230
]
} |
phase ii trial of carboplatin in advanced breast carcinoma : a cancer and leukemia group b study . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
63,
69
]
} | {
"id": "C0023418",
"name": "group",
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83,
88
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} |
in order to study the role of platelets in migraine and cerebrovascular disease , beta-thromboglobulin ( beta-tg ) and platelet factor 4 ( pf4 ) plasma levels , indices of in vivo platelet activation , were assayed in two groups of patients suffering from migraine ( common/classic and classic/complicated migraine , respectively ) and in one group suffering from transitory ischemic attacks ( tias ) . | nichd_parent_of | {
"id": "C0149931",
"name": "migraine",
"pos": [
43,
51
]
} | {
"id": "C0154723",
"name": "classic",
"pos": [
286,
293
]
} |
changes in erythrocyte deformability ( ed ) parameters have been investigated in 36 patients suffering from different forms of headache ( classic and common migraine ; migraine with interval headache ; chronic tension headache ) and treated with flunarizine ( 10 mg/day at bedtime ) . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
127,
135
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
168,
176
]
} |
patients with headache had undergone more recent stressful events than the control individuals , and the difference was due to patients with migraine . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
14,
22
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
141,
149
]
} |
firstly , a horizontal study on 57 patients with definite stroke and on 49 patients with tia was made . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
58,
64
]
} | {
"id": "C0007787",
"name": "tia",
"pos": [
89,
92
]
} |
following this , a longitudinal study was performed on 27 patients with definite stroke and 32 patients with tia . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
81,
87
]
} | {
"id": "C0007787",
"name": "tia",
"pos": [
109,
112
]
} |
finally , 81 patients with clinical diagnosis of cerebrovascular disease due to previous stroke or repeated tia were studied together . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
89,
95
]
} | {
"id": "C0007787",
"name": "tia",
"pos": [
108,
111
]
} |
we wanted to determine whether the microscopic evaluation of urinary sediment could be replaced by either a biochemical determination ( chemstrip-9 ) or a colorimetric staining procedure ( bac-t-screen ) , and to evaluate the feasibility of omitting from urinalyses attempts to culture urines . | nichd_parent_of | {
"id": "C0184661",
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186
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} | {
"id": "C0220825",
"name": "evaluate",
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213,
221
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} |
various degrees of bone marrow aplasia have been described in association with distinctive congenital anomalies such as the fanconi pancytopenia syndrome ( f.p.s . ) , thrombocytopenia absent radii syndrome ( t.a.r . syndrome ) the aase syndrome and diamond-blackfan anemia . | nichd_parent_of | {
"id": "C0002874",
"name": "bone marrow aplasia",
"pos": [
19,
38
]
} | {
"id": "C0015625",
"name": "fanconi pancytopenia",
"pos": [
124,
144
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} |
the aetiology of the autoimmune disorder in this subgroup may differ from that in other mg patients . | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune disorder",
"pos": [
21,
40
]
} | {
"id": "C0026896",
"name": "mg",
"pos": [
88,
90
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} |
in order to evaluate the efficacy of exercise electrocardiography ( ecg ) to identify jeopardized myocardial regions remote from the site of previous infarction , exercise ecg , left ventriculography , and coronary arteriography were performed in 90 patients with previous transmural myocardial infarction ( mi ) . | nichd_parent_of | {
"id": "C0021308",
"name": "infarction",
"pos": [
150,
160
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
284,
305
]
} |
ccta were always negative in 18 patients with systemic lupus erythematosus and were found in one out of 8 cases with sjogren 's syndrome , also positive for rheumatoid factor without clinical ra . | nichd_parent_of | {
"id": "C0003241",
"name": "ccta",
"pos": [
0,
4
]
} | {
"id": "C0035448",
"name": "rheumatoid factor",
"pos": [
157,
174
]
} |
in chronic lupus nephropathy with inactive sle maternal and fetal outcome is the same as for pregnant patients with chronic renal disease of other causes . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
17,
28
]
} | {
"id": "C0022661",
"name": "chronic renal",
"pos": [
116,
129
]
} |
eight patients with larsen 's syndrome were investigated and found to have a characteristic pattern of spinal deformity consisting of vertebral anomalies , spondylolysis , and scoliosis . | nichd_parent_of | {
"id": "C0575157",
"name": "spinal deformity",
"pos": [
103,
119
]
} | {
"id": "C0036439",
"name": "scoliosis",
"pos": [
176,
185
]
} |
eleven clinical and behavioral syndromes that can result in self-inflicted injury in childhood and adolescence are reviewed and classified . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
85,
94
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
99,
110
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} |
it is important to distinguish between depletion of soft tissues and stunting of linear skeletal growth , not only in older infants and children , but also in newborn infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
136,
144
]
} | {
"id": "C0021289",
"name": "newborn infants",
"pos": [
159,
174
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} |
the procedure , performed portably in the cardiac care unit , was selected because progressive cardiac and renal decompensation made the patient an extremely poor surgical risk . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
4,
13
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
163,
171
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} |
in some cases , ct alone may be the only imaging procedure necessary , while in other situations , ct may comprise an important portion of comprehensive imaging evaluation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
49,
58
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
161,
171
]
} |
malassezia is a common infection that must be differentiated from the cutaneous manifestations of systemic candidiasis . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
23,
32
]
} | {
"id": "C0153252",
"name": "systemic",
"pos": [
98,
106
]
} |
recognition of this normal finding -- due to lead construction -- will help avoid erroneous diagnosis of wire fracture on chest x-ray films . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
27,
34
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} | {
"id": "C0011900",
"name": "diagnosis",
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92,
101
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} |
although this procedure proved effective for up to 36 months in patients who had had no previous antireflux procedure , the displacement rate ( 3/16 = 19 % ) , reoperation rate ( 3/16 = 19 % ) , and the progressive decline in les pressure over time should make one cautious about its routine use in the surgical treatment of reflux esophagitis . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
14,
23
]
} | {
"id": "C0543467",
"name": "surgical treatment",
"pos": [
303,
321
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} |
an increase in ventricular arrhythmias in the hour prior to death was observed in about 50 % of patients and the r-on-t phenomenon , as the initiating mechanism for ventricular tachycardia , in 42 % . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
15,
38
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
165,
188
]
} |
interestingly , the finding of large numbers of igf-i and igf-ii receptors on endothelial cells suggests that these growth factors play a physiological role and are involved in vascular complications associated with diabetes . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
20,
27
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} | {
"id": "C0009566",
"name": "complications",
"pos": [
186,
199
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} |
furthermore , the technique was successfully used for hemostasis and tumor reduction in inoperable early cancer cases . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
69,
74
]
} | {
"id": "C0006826",
"name": "cancer",
"pos": [
105,
111
]
} |
the incidence of typhoid fever in vaccinees was 1.1 per 10,000 doses of ty 21a vaccine sold , which was similar to the incidence of 0.9 per 10,000 doses for the ineffective killed ty 2 vaccine . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccine",
"pos": [
34,
41
]
} | {
"id": "C0042212",
"name": "killed",
"pos": [
173,
179
]
} |
our data indicate that in tumors , abnormalities of the hemostatic system are an early phenomenon unrelated to the presence of widespread malignancy . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
26,
32
]
} | {
"id": "C0006826",
"name": "malignancy",
"pos": [
138,
148
]
} |
the electrophysiological effects of flecainide , 0.1 , 0.5 and 1.0 mg/l , on action potential characteristics were examined in normal purkinje fibers and purkinje fibers surviving infarction , at stimulation cycle lengths of 1000 and 300 ms . | nichd_parent_of | {
"id": "C1521970",
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"pos": [
94,
109
]
} | {
"id": "C1444754",
"name": "lengths",
"pos": [
214,
221
]
} |
major clinical signs in the former period were death and diarrhea , which occurred usually within a week after arrival of the guinea pigs at our institute and caused significant decrease of body weight , but those in the latter period were retarded growth and weakness which became detectable during 1-3 weeks after arrival of the animals . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
6,
20
]
} | {
"id": "C0011065",
"name": "death",
"pos": [
47,
52
]
} |
major clinical signs in the former period were death and diarrhea , which occurred usually within a week after arrival of the guinea pigs at our institute and caused significant decrease of body weight , but those in the latter period were retarded growth and weakness which became detectable during 1-3 weeks after arrival of the animals . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
6,
20
]
} | {
"id": "C3714552",
"name": "weakness",
"pos": [
260,
268
]
} |
present findings support the view that surfactant defects are of importance in the pathogenesis of respiratory disease , and that surfactant-oriented therapy may be effective in the treatment and prevention of respiratory failure . | nichd_parent_of | {
"id": "C0035204",
"name": "respiratory disease",
"pos": [
99,
118
]
} | {
"id": "C1145670",
"name": "respiratory failure",
"pos": [
210,
229
]
} |
among 9 viral diseases , such as measles , varicella , erythema infection , hand-foot and mouth disease , rubella , mumps , influenza , epidemic keratoconjunctivitis and acute hemorrhagic conjunctivitis observed in northern japan and miyagi prefecture in the past 4 years , mumps , hand-foot and mouth disease and epidemic keratoconjunctivitis were prevalent in summer . | nichd_parent_of | {
"id": "C0042769",
"name": "viral diseases",
"pos": [
8,
22
]
} | {
"id": "C0035920",
"name": "rubella",
"pos": [
106,
113
]
} |
among 9 viral diseases , such as measles , varicella , erythema infection , hand-foot and mouth disease , rubella , mumps , influenza , epidemic keratoconjunctivitis and acute hemorrhagic conjunctivitis observed in northern japan and miyagi prefecture in the past 4 years , mumps , hand-foot and mouth disease and epidemic keratoconjunctivitis were prevalent in summer . | nichd_parent_of | {
"id": "C0042769",
"name": "viral diseases",
"pos": [
8,
22
]
} | {
"id": "C0021400",
"name": "influenza",
"pos": [
124,
133
]
} |
among 9 viral diseases , such as measles , varicella , erythema infection , hand-foot and mouth disease , rubella , mumps , influenza , epidemic keratoconjunctivitis and acute hemorrhagic conjunctivitis observed in northern japan and miyagi prefecture in the past 4 years , mumps , hand-foot and mouth disease and epidemic keratoconjunctivitis were prevalent in summer . | nichd_parent_of | {
"id": "C0042769",
"name": "viral diseases",
"pos": [
8,
22
]
} | {
"id": "C0018572",
"name": "hand-foot and mouth disease",
"pos": [
282,
309
]
} |
to determine whether exercise testing performed soon after myocardial infarction may predict the degree of coronary artery disease , 78 patients performed stress testing and coronary angiography 15 +/- 5 and 64 +/- 35 days , respectively , after myocardial infarction . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
16,
19
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
246,
267
]
} |
finally the characteristics of patients at risk of cardiac rupture following myocardial infarction seem to be : absence of previous infarctions , anterior localization of ami , sustained hypertension after myocardial infarction , absence of serious hemodynamic and arrhythmic complications . | nichd_parent_of | {
"id": "C0021308",
"name": "infarctions",
"pos": [
132,
143
]
} | {
"id": "C0027051",
"name": "myocardial",
"pos": [
206,
216
]
} |
nearly 20 cases have been reported : congenital heart diseases previously reported are atrial septal defect , ventricular septal defect and hypoplastic left heart . | nichd_parent_of | {
"id": "C0152021",
"name": "congenital heart diseases",
"pos": [
37,
62
]
} | {
"id": "C0152101",
"name": "hypoplastic left heart",
"pos": [
140,
162
]
} |
in patients with acute lymphoblastic leukemia , 43 out of 52 cases ( 83 % ) were positive and , in particular , all of 12 t-cell-type acute leukemias were reactive to hh 10 . | nichd_parent_of | {
"id": "C0023449",
"name": "acute lymphoblastic",
"pos": [
17,
36
]
} | {
"id": "C1961099",
"name": "t-cell-type acute leukemias",
"pos": [
122,
149
]
} |
the distribution of the number of hla haplotypes shared by sibs affected with the same hla-linked disease can be used to obtain information on the genetics of the disease . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
98,
105
]
} | {
"id": "C0019247",
"name": "genetics",
"pos": [
147,
155
]
} |
in conclusion , improved hbfp staining method is useful in identifying early myocardial ischemia and extent of early infarcts , and explaining for sudden death due to re-attack of myocardial infarction . | nichd_parent_of | {
"id": "C0021308",
"name": "infarcts",
"pos": [
117,
125
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
180,
201
]
} |
on the basis of the hematologic and clinical findings , chronic myeloid leukemia was diagnosed in six of these cases , myelomonocytic leukemia in three cases , and acute myeloid leukemia in two cases . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical",
"pos": [
36,
44
]
} | {
"id": "C0011900",
"name": "diagnosed",
"pos": [
85,
94
]
} |
the possible genetic linkage between hla and neuraminidase deficiency was studied in a female patient with combined abnormalities of the infantile form of sialidosis type ii and congenital adrenal hyperplasia caused by 21-hydroxylase deficiency , and six members of her family . | nichd_parent_of | {
"id": "C0000768",
"name": "abnormalities",
"pos": [
116,
129
]
} | {
"id": "C0001627",
"name": "congenital adrenal hyperplasia",
"pos": [
178,
208
]
} |
it is proposed that the combination of exposure of growth plate cartilage during normal bone growth and the ability of s. aureus to adhere to this cartilage is the mechanism for initiation of infection which proceeds to an osteomyelitic abscess . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
192,
201
]
} | {
"id": "C0000833",
"name": "abscess",
"pos": [
237,
244
]
} |
the level of elevation parallels the degree of malignancy in melanoma and in tumors of mesenchymal origin . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
47,
57
]
} | {
"id": "C0025202",
"name": "melanoma",
"pos": [
61,
69
]
} |
the tumor was composed mainly of small epithelial cells of sex cord type , but also contained multiple foci in which the presence of large cells resembling germ cells warranted the diagnosis of mixed germ cell-sex cord-stromal tumor . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
4,
9
]
} | {
"id": "C1321220",
"name": "mixed germ cell-sex",
"pos": [
194,
213
]
} |
from these results it was concluded that the most reliable predictors of behavior upon awakening were : the amount of wakefulness prior to sleep , the total amount of accrued sleep , circadian time as indexed by body temperature , and depth of sleep . | nichd_parent_of | {
"id": "C0004927",
"name": "behavior",
"pos": [
73,
81
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
244,
249
]
} |
the total group included nonspecific ( viral ) pericarditis in 35 patients ( 32.4 % ) , uremic pericarditis in 30 ( 27.8 % ) ; | nichd_parent_of | {
"id": "C0031046",
"name": "pericarditis",
"pos": [
47,
59
]
} | {
"id": "C0265152",
"name": "uremic pericarditis",
"pos": [
88,
107
]
} |
these results suggest that at all ages except 18 mo , it should be possible to use the opl procedure as a vision screening tool by testing individual children with the diagnostic grating frequency appropriate for their age . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
139,
149
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
150,
158
]
} |
patients with low-tension glaucoma had headaches with or without features of migraine ( unilateral headache , nausea or vomiting , or visual prodromata ) more frequently than did any of the other groups . | nichd_parent_of | {
"id": "C0018681",
"name": "headaches",
"pos": [
39,
48
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
77,
85
]
} |
clinical signs consisted of cervical pruritus , a stiff gait involving the forelimbs , and decreased range of motion of the scapulohumeral joints . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
0,
14
]
} | {
"id": "C0033774",
"name": "pruritus",
"pos": [
37,
45
]
} |
however , trienomycin a showed no antimicrobial activity against the bacteria , fungi and yeasts examined with the exception of weak activity versus piricularia oryzae at a concentration of 1,000 micrograms/ml . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
80,
85
]
} | {
"id": "C0043393",
"name": "yeasts",
"pos": [
90,
96
]
} |
to assess the results of this combination procedure , fifty hips in forty-four children were evaluated at an average of six years postoperatively . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
42,
51
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
93,
102
]
} |
the combination osteotomy has the advantages of both the pemberton procedure and the salter operation and proved to be an excellent surgical procedure for older children whose acetabular development did not progress as well as was expected . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
67,
76
]
} | {
"id": "C0543467",
"name": "surgical procedure",
"pos": [
132,
150
]
} |
the characteristic radiologic features of this condition are minute loculations of contrast medium adjacent to the tubal lumen which range in size up to 2 mm in diameter and are clustered together over a tubal length of 1 to 2 cm . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
30,
38
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
210,
216
]
} |
this justifies the continuing use of axillopopliteal bypass in an effort to salvage those limbs imminently threatened with amputation and in which no standard reconstruction is feasible because of disease or infection . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
197,
204
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
208,
217
]
} |
these data demonstrate disordered 1,25- ( oh ) 2d production as opposed to metabolic clearance in the syndrome of absorptive hypercalciuria . | nichd_parent_of | {
"id": "C0012634",
"name": "disordered",
"pos": [
23,
33
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
102,
110
]
} |
when 177 sera from patients with fungal diseases other than paracoccidioidomycosis were tested by immunodiffusion , there were no false-positive reactions . | nichd_parent_of | {
"id": "C0026946",
"name": "fungal diseases",
"pos": [
33,
48
]
} | {
"id": "C0030409",
"name": "paracoccidioidomycosis",
"pos": [
60,
82
]
} |
our results suggest a novel mechanism by which disease can be incurred : a heritable disorder can result from a posttranslational processing abnormality caused by a point mutation . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
47,
54
]
} | {
"id": "C0019247",
"name": "heritable disorder",
"pos": [
75,
93
]
} |
both procedures caused loss of attachment and bony support from adjacent tooth surfaces involved by the surgical procedure . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
5,
15
]
} | {
"id": "C0543467",
"name": "surgical procedure",
"pos": [
104,
122
]
} |
in the absence of these organisms , and until additional periodontal pathogens have become known , the decision to continue or conclude periodontal therapy must b | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
24,
33
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
69,
78
]
} |
tumors examined were hepatomas ( five patients ) , liver metastases ( 17 ) , hemangiomas ( seven ) , biliary carcinomas ( eight ) , pancreatic carcinomas ( five ) , renal tumors ( 15 ) , adrenal tumors ( eight ) , uterine tumors ( 17 ) , bladder carcinomas ( five ) , prostatic carcinomas ( 13 ) , bone tumors ( six ) , and lung carcinomas ( 15 ) . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
0,
6
]
} | {
"id": "C0018916",
"name": "hemangiomas",
"pos": [
77,
88
]
} |
it was found that violence by young people toward their parents tended to be concentrated in households with strong manifestations of intra-family violence or aggression between the parents , between parents and children , and between siblings . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
36,
42
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
212,
220
]
} |
this procedure offered a surgical alternative to an alloy retrofilling , when the usual apexification process was not successful . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
5,
14
]
} | {
"id": "C0543467",
"name": "surgical",
"pos": [
25,
33
]
} |
it emerged that while there was not an uncritical acceptance of behavioural objectives , they were seen as having a place in the process of teaching and learning nursing . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioural",
"pos": [
64,
75
]
} | {
"id": "C0006147",
"name": "nursing",
"pos": [
162,
169
]
} |
multivariate logistic regression analysis revealed that the presenting arrhythmia was a potent and independent predictor of the ability to provoke ventricular arrhythmias at electrophysiologic study ; | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
71,
81
]
} | {
"id": "C0085612",
"name": "ventricular",
"pos": [
147,
158
]
} |
of patients presenting with sustained ventricular tachycardia , 89 % ( 81 of 91 ) had inducible ventricular arrhythmias compared with 61 ( 40 of 66 ) and 66 % ( 69 of 104 ) of patients with nonsustained ventricular tachycardia and ventricular fibrillation , respectively . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular",
"pos": [
38,
49
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
231,
255
]
} |
complex ventricular arrhythmias are defined as lown grades 4a ( couplets ) , 4b ( ventricular tachycardia ) and 5 ( r on t phenomenon ) . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
8,
31
]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
"pos": [
82,
105
]
} |
prevalence and significance of cardiovascular disease and hypertension in elderly patients with dementia and depression . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular disease",
"pos": [
31,
53
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
58,
70
]
} |
the increased attention to and appreciation of mental content in childhood especially augmented freud 's understanding of the role of drive objects , object directedness , and object choice in infancy . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
65,
74
]
} | {
"id": "C0231330",
"name": "infancy",
"pos": [
193,
200
]
} |
a tissue processing procedure was evaluated for fixation of endogenous long-chain acyl carnitine ( lca ) to facilitate autoradiographic subcellular localization of this amphiphile . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
20,
29
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
34,
43
]
} |
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