text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
the staining pattern along the cytoplasmic membrane was specific for malignancy and occurred in 29 % of the breast carcinomas . | nichd_parent_of | {
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these preliminary data suggest that a particular pattern of cytokine changes is associated with vasculitis and that cytokines might be involved in the pathogenesis of pan/csa and wg . | nichd_parent_of | {
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"name": "vasculitis",
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} | {
"id": "C0031036",
"name": "pan",
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this highlights the areas that we do not yet understand , namely the interplay of genetic susceptibility , extrinsic agents or disorders of immune regulation which permit the autoimmune process to become sufficiently pronounced as to engender a clinical autoimmune disease . | nichd_parent_of | {
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} | {
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} |
histopathologically , these neoplasms were classified as oligodendrogliomas , ranging from early neoplastic foci to large , infiltrating malignant tumours . | nichd_parent_of | {
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"name": "neoplasms",
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"name": "malignant tumours",
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the notion that cancer is a genetic disease has gained increasing credence from the now numerous studies in which specific alterations of chromosome and of gene structure and activity in a variety of cancers have been identified , and , in particular , with the increasing awareness of the heritability of factors that predispose to the development of early , specific cancers in the offspring of parents carrying these predisposing genes . | nichd_parent_of | {
"id": "C0019247",
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immunosuppression with cyclosporine a affects host defense mechanisms which are operative against superficial candidiasis but appear superfluous in resistance to the invasive form of this mycosis , an indication for the divergent nature of host defense against the two forms of candidiasis . | nichd_parent_of | {
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in this study it was determined that while fibronectin was able to significantly increase phagocytosis of organisms grown in static broth , uptake of agitated bacteria could not be promoted . | nichd_parent_of | {
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} | {
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immunotoxicity was assessed using the enzyme-linked immunoabsorbant assay ( elisa ) for humoral immunity , a delayed-type hypersensitivity ( dth ) procedure for cell-mediated immunity , and natural killer cell ( nkc ) activity to evaluate spontaneous cytotoxicity . | nichd_parent_of | {
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the well known excess of cancer cases among boys compared to girls was due mainly to the occurrence of 90 % more lymphomas , 30 % more leukaemias and 15 % more tumours of the central nervous system ( cns ) among boys . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
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31
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} | {
"id": "C0024299",
"name": "lymphomas",
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while the increase in the incidence of cns tumours was explained at least partly by better cancer surveillance , no interpretation can be offered for the increases seen for neuroblastomas and lymphomas . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
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} | {
"id": "C0024299",
"name": "lymphomas",
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between one-sixth and one-fifth of major chd events occur among patients with previous mi or angina pectoris . | nichd_parent_of | {
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} | {
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factors such as age , time of admission to the ccu , use of thrombolytic agents , patency of the infarct related artery , left ventricular ejection fraction , smoking status as well as conventional risk factors need to be assessed before a valid comparison can be made or conclusions reached concerning trends in mortality after mi . | nichd_parent_of | {
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} | {
"id": "C0027051",
"name": "mi",
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} |
ovarian endometrioid carcinomas resembling sex cord-stromal tumors ( ecscss ) may simulate sertoli cell tumors , sertoli-leydig cell tumors ( slcts ) , and adult granulosa cell tumors ( agcts ) , both clinically and pathologically . | nichd_parent_of | {
"id": "C0206724",
"name": "sex cord-stromal tumors",
"pos": [
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66
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} | {
"id": "C0036769",
"name": "sertoli cell tumors",
"pos": [
91,
110
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} |
ovarian endometrioid carcinomas resembling sex cord-stromal tumors ( ecscss ) may simulate sertoli cell tumors , sertoli-leydig cell tumors ( slcts ) , and adult granulosa cell tumors ( agcts ) , both clinically and pathologically . | nichd_parent_of | {
"id": "C0206724",
"name": "sex cord-stromal tumors",
"pos": [
43,
66
]
} | {
"id": "C0018206",
"name": "granulosa cell tumors",
"pos": [
162,
183
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} |
the etiology of hydrocephalus was classified into 5 groups as follows : perinatal intraventricular hemorrhage 19 , congenital obstructive hydrocephalus 15 , intracranial cysts 5 , severe intracranial anomalies 4 and central nervous system infections 4 children . | nichd_parent_of | {
"id": "C0020255",
"name": "hydrocephalus",
"pos": [
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} | {
"id": "C0020256",
"name": "congenital",
"pos": [
115,
125
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} |
in patients with tumor thickness exceeding 10 mm , recurrences occurred in 58 % ( p less than 0.0048 ) , and 87 % ( p less than 0.0164 ) died of their cancer . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
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22
]
} | {
"id": "C0006826",
"name": "cancer",
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157
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} |
on the basis of certain fundamental data for pathological hearing in children and its effects on speech development an attempt is made to summarise the most important considerations regarding the primary choice of a device and the subsequent procedures of fitting to optimise the benefits over a range of ages , from the small infant to school age children . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
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} | {
"id": "C0021270",
"name": "infant",
"pos": [
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} |
we believe that clinicians and researchers who evaluate and treat adolescents should view the physical and emotional complaints of teenagers in the context of our findings . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
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} | {
"id": "C0031809",
"name": "physical",
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} |
about 60 % of the girls in g2 had living children at home , but they were more likely than those in g1 to state that they became pregnant because they wanted a baby ( g2 44 % , g1 21 % ; p less than 0.01 ) and , conversely , girls in g1 were more likely than those in g2 to state that the pregnancy was an accident and `` '' just happened '' '' ( g1 61 % , g2 37 % ; p less than 0.01 ) . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
41,
49
]
} | {
"id": "C0021270",
"name": "baby",
"pos": [
160,
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} |
cause , occurrence , and clinical signs of mastitis and anorexia in cows in a wisconsin study . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
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39
]
} | {
"id": "C0003123",
"name": "anorexia",
"pos": [
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} |
haloperoxidases have been detected in a variety of organisms , including bacteria , fungi , algae , and mammals . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
51,
60
]
} | {
"id": "C0004611",
"name": "bacteria",
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} |
haloperoxidases have been detected in a variety of organisms , including bacteria , fungi , algae , and mammals . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
51,
60
]
} | {
"id": "C0016832",
"name": "fungi",
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} |
the system provides , for the first time ever in any throwing event , the ability to critique nearly instantly in a precise , quantitative manner the crucial factors in the throw which determine the range . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
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126,
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} | {
"id": "C1514721",
"name": "range",
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199,
204
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} |
none of 21 randomly collected sputum specimens tested contained fluorescing legionellalike organisms , but 6 specimens did contain brightly fluorescing bacteria atypical in morphology for legionella species . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
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91,
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]
} | {
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"name": "bacteria",
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} |
superficially , the more lethal disease induced by beta-endorphin appeared to be a result of a mild hypothermia caused by the neuropeptide . beta-endorphin , however , did not influence the disease in nude ( nu/nu ) mice even though their core temperatures were reduced to an extent similar to that of balb/c ( +/+ ) mice , implicating the involvement of t lymphocytes in the alteration of the course of infection in normal mice . | nichd_parent_of | {
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"name": "disease",
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} | {
"id": "C0009450",
"name": "infection",
"pos": [
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} |
binding of piliated organisms to hydrophobic surfaces was significantly higher compared to both nonpiliated bacteria and the adherence of piliated rdec-1 to relatively hydrophilic surfaces . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
20,
29
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
108,
116
]
} |
the procedure for preparing the muscle pedicle beneath the cervical skin tunnel was carried out without much difficulty by carefully preparing the surgical field . | nichd_parent_of | {
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"name": "procedure",
"pos": [
4,
13
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} | {
"id": "C0543467",
"name": "surgical",
"pos": [
147,
155
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} |
because of the opportunistic nature of these organisms and the prevalence of immunodeficient conditions , the number of medically important fungi is increasing . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
45,
54
]
} | {
"id": "C0016832",
"name": "fungi",
"pos": [
140,
145
]
} |
the prognostic importance of coronary artery disease at the time of elective abdominal aortic aneurysmectomy was evaluated among 131 residents of olmsted county , minnesota who underwent elective aneurysmectomy from 1971 to 1987 and were followed up to 1988 for death and cardiac events ( cardiac death , myocardial infarction , coronary bypass surgery and angioplasty ) . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
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3
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} | {
"id": "C0027051",
"name": "myocardial",
"pos": [
305,
315
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} |
nicardipine , a new dihydropyridine calcium channel blocker , has been investigated for the treatment of coronary artery disease and heart failure . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
88,
91
]
} | {
"id": "C0018801",
"name": "heart failure",
"pos": [
133,
146
]
} |
sixty minutes after the start of infusion , 54 ( 74 % ) of 73 patients had a patent infarct-related artery ( thrombolysis in myocardial infarction [ timi ] grade 2 or 3 ) as did 67 ( 91 % ) of 74 patients at 90 min . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
84,
91
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
125,
146
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} |
thus , a procedure was developed to evaluate further the relationship between mediator release , as measured by plasma histamine concentrations , and airway obstruction in patients with allergic rhinitis challenged with inhaled ragweed antigen . | nichd_parent_of | {
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} | {
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} |
the runners ' supplementation patterns with respect to demographics , dietary quality , training habits , and race performance were investigated . | nichd_parent_of | {
"id": "C0011298",
"name": "demographics",
"pos": [
55,
67
]
} | {
"id": "C0034510",
"name": "race",
"pos": [
110,
114
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} |
three behavioral measures that can be easily collected by nursing staff significantly predicted continence levels during treatment ( multiple r , 0.79 ) and change in incontinence during treatment ( multiple r , 0.64 ) . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
6,
16
]
} | {
"id": "C0006147",
"name": "nursing",
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58,
65
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} |
the major complication of this therapy is hemorrhage , with intracranial hemorrhage having the highest morbidity and mortality . | nichd_parent_of | {
"id": "C0019080",
"name": "hemorrhage",
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42,
52
]
} | {
"id": "C0151699",
"name": "intracranial hemorrhage",
"pos": [
60,
83
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} |
rg-tsf/tgf-beta 2 also has an inhibiting effect on ctl-mediated disease in lcmv-infected mice : it prolonged the survival time of mice infected with lcmv and reduced the local swelling reaction after infection into the footpad . | nichd_parent_of | {
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64,
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} | {
"id": "C0009450",
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200,
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} |
an association of igm mab against gangliosides with peripheral neuropathies has been reported recently , but only one of five patients whose antibodies reacted with gm1 ganglioside had a neuropathy . | nichd_parent_of | {
"id": "C0031117",
"name": "peripheral neuropathies",
"pos": [
52,
75
]
} | {
"id": "C0442874",
"name": "neuropathy",
"pos": [
187,
197
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} |
we compared nine different techniques for the detection of biotinylated dna-dna hpv hybrids on hela cells with 10-50 copies of hpv 18 dna per cell . | nichd_parent_of | {
"id": "C0021344",
"name": "hpv",
"pos": [
80,
83
]
} | {
"id": "C0999807",
"name": "hpv 18",
"pos": [
127,
133
]
} |
with the one step reaction ( an avidin-horseradish peroxidase , or streptavidin-alkaline phosphatase or streptavidin-fluorescein complex ) , no labeling of hela cells was observed with any of the hpv probes , including hpv 18 . | nichd_parent_of | {
"id": "C0021344",
"name": "hpv",
"pos": [
196,
199
]
} | {
"id": "C0999807",
"name": "hpv",
"pos": [
219,
222
]
} |
purified acellular pertussis vaccine ( 12.5 micrograms of lymphocytosis promoting factor [ lpf ] and 12.5 micrograms of filamentous hemagglutinin [ fha ] ) was compared with conventional pertussis vaccine in a randomized double-blind study involving 40 children aged 4-6 y , 40 children aged 18-24 mo , and 50 infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
253,
261
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
310,
317
]
} |
infections caused by weak-bacteria , i.e. , opportunistic infections , have increased in the bacterial infections of genital organs . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
0,
10
]
} | {
"id": "C0004623",
"name": "bacterial infections",
"pos": [
93,
113
]
} |
the percentages of young people , students , children and grandchildren of the patient , the contacts of multibacillary leprosy cases , long duration of contact , bcg vaccination , fla-abs and dharmendra 's lepromin-positive responders were significantly higher in the household contacts than those in the villagers . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
25,
31
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
63,
71
]
} |
among children aged less than 5 years ( with or without diarrhea ) the viruses were more frequently observed in stools from young children ( 1-5 years old ) than from the newborn ( less than 1-year-old ) particularly those living in the bang khen slum area and in the rural khon kaen community . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
6,
14
]
} | {
"id": "C0021289",
"name": "newborn",
"pos": [
171,
178
]
} |
clinical effectiveness of the procedure is evaluated in a survey of 1,200 patients in whom it was used . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
30,
39
]
} | {
"id": "C0220825",
"name": "evaluated",
"pos": [
43,
52
]
} |
relationships between the extent of psychopathology and the occurrence of 21 major life events during five developmental periods ( prebirth , infancy , childhood , latency , and adolescence ) were examined with multiple regression and x2 analyses for 114 hospitalized male and female adolescents . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
152,
161
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
178,
189
]
} |
by analogy with autoimmune disease of the cns such as multiple sclerosis , in which excessive cell-mediated immunity is found , several possible immunological maneuvers are suggested . | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune disease",
"pos": [
16,
34
]
} | {
"id": "C0026769",
"name": "multiple sclerosis",
"pos": [
54,
72
]
} |
the qualitative descriptive approach of phenomenology was utilized to define the meaning of health for graduate nursing students . | nichd_parent_of | {
"id": "C0205556",
"name": "qualitative",
"pos": [
4,
15
]
} | {
"id": "C0018684",
"name": "health",
"pos": [
92,
98
]
} |
these studies are grouped as isolated maxillary and mandibular procedures , simultaneous two-jaw procedures , and procedures used to treat syndrome/cleft palate patients . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
63,
73
]
} | {
"id": "C0087111",
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133,
138
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} |
this study describes an attempt to define intrauterine growth retardation low birth weight preterm infants by comparing reference standards for intrauterine growth in weight , length , and head circumference on their variability across ethnic groups and cities , and on their specificity in independently classifying infants as short , thin , or having small heads . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
176,
182
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
189,
207
]
} |
these differences , as well as the potentially false overlap of classification , were attenuated when the use of gestational age as a reference standard was used only for birth length , while length itself was used ( as an alternative to gestational age ) as the reference standard for birth weight , and weight was used as the reference standard for head circumference . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
177,
183
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
351,
369
]
} |
leiomyomas associated with familial syndromes ( familial leiomyoma and alport 's syndrome ) occur in 22 % of the cases . | nichd_parent_of | {
"id": "C0039082",
"name": "syndromes",
"pos": [
36,
45
]
} | {
"id": "C1567741",
"name": "alport 's syndrome",
"pos": [
71,
89
]
} |
it remains unclear whether in utero puncture of the cyst and evacuation of its content should be justified in cases of particularly large ovarian cyst . | nichd_parent_of | {
"id": "C0010709",
"name": "cyst",
"pos": [
52,
56
]
} | {
"id": "C0029927",
"name": "ovarian cyst",
"pos": [
138,
150
]
} |
a sample of children treated by phototherapy during the neonatal period has been studied in the population of penne ( south eastern italy ) in order to confirm the association previously reported in newborns from the population of rome between neonatal jaundice and phenotypes of adenosine deaminase ( ada ) and acid phosphatase ( acp1 ) . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
12,
20
]
} | {
"id": "C0021289",
"name": "newborns",
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199,
207
]
} |
these results indicate that em-523 mimics motilin in stimulating gastrointestinal motility and that this agent may be useful treat gastrointestinal disorders such as gastric stasis , gastroesophageal reflux , and postoperative ileus , and so forth . | nichd_parent_of | {
"id": "C0017178",
"name": "gastrointestinal disorders",
"pos": [
131,
157
]
} | {
"id": "C0017168",
"name": "gastroesophageal reflux",
"pos": [
183,
206
]
} |
the accepted procedure for evaluating women with inflammatory atypia on a papanicolaou smear has changed over the years . | nichd_parent_of | {
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"name": "procedure",
"pos": [
13,
22
]
} | {
"id": "C0220825",
"name": "evaluating",
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27,
37
]
} |
when controlled for age , no apparent difference could be shown in the level of keratan sulfate in the serum of the dogs as a result of the procedure ( ligament transection or sham operation ) or time after operation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
140,
149
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
207,
216
]
} |
the seroepidemiology of infection due to rubella virus in saudi arabia was investigated in various age groups including unvaccinated children ( newborn to 15 years of age ) using a newer rubella antibody test system , the elisa with maximum sensitivity and reliability . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
133,
141
]
} | {
"id": "C0021289",
"name": "newborn",
"pos": [
144,
151
]
} |
the occlusions were associated with ipsilateral strokes in six ( 25 % ) , ipsilateral transient ischemic attacks in four ( 16 % ) , and the onset of nonhemispheric symptoms in one ( 5 % ) . | nichd_parent_of | {
"id": "C0038454",
"name": "strokes",
"pos": [
48,
55
]
} | {
"id": "C0007787",
"name": "transient ischemic attacks",
"pos": [
86,
112
]
} |
late neurologic events comprised two strokes , three transient ischemic attacks and the onset of nonhemispheric symptoms in six , which in some were disabling . | nichd_parent_of | {
"id": "C0038454",
"name": "strokes",
"pos": [
37,
44
]
} | {
"id": "C0007787",
"name": "transient ischemic attacks",
"pos": [
53,
79
]
} |
for late events by life-table analysis , the average annual rate over the first 2 years for stroke was 10 % and for transient ischemic attack 13 % . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
92,
98
]
} | {
"id": "C0007787",
"name": "transient ischemic attack",
"pos": [
116,
141
]
} |
young bears which are exposed to the virus may develop clinical disease and die as a result of the infection . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
64,
71
]
} | {
"id": "C0009450",
"name": "infection",
"pos": [
99,
108
]
} |
it was concluded that each organism had acted as an opportunistic pathogen in its compromised host . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
27,
35
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
66,
74
]
} |
cpdx-pr was administered to 37 pediatric patients with various bacterial infections ( pyelonephritis 9 , cystitis 4 , pneumonia 7 , acute bronchitis 3 , otitis media 2 , tonsillitis 10 , subcutaneous abscess 1 and purulent lymphadenitis 1 ) . | nichd_parent_of | {
"id": "C0004623",
"name": "bacterial infections",
"pos": [
63,
83
]
} | {
"id": "C0034186",
"name": "pyelonephritis",
"pos": [
86,
100
]
} |
organisms suspected as pathogens were 32 strains ( 6 strains of staphylococcus aureus , 2 of streptococcus pyogenes , 1 of enterococcus faecalis , 15 of haemophilus influenzae , 5 of haemophilus parainfluenzae and 3 of escherichia coli ) . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
0,
9
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
23,
32
]
} |
it was suggested that the autoantibodies to cytoskeletal systems associated with viral infection were mainly composed of igg in atl and of igm in infectious mononucleosis . | nichd_parent_of | {
"id": "C0042769",
"name": "viral infection",
"pos": [
81,
96
]
} | {
"id": "C0021345",
"name": "infectious mononucleosis",
"pos": [
146,
170
]
} |
these observations suggested that complement activation , probably brought about by massive bacterial infection , induced the impairment of neutrophil functions and resulted in a further breakdown of the host defence system , thereby leading to sepsis . | nichd_parent_of | {
"id": "C0004623",
"name": "bacterial infection",
"pos": [
92,
111
]
} | {
"id": "C0036690",
"name": "sepsis",
"pos": [
245,
251
]
} |
upper gastrointestinal x-ray series revealed a slow growing submucosal tumor in the anterior wall of the antrum of the stomach which was subsequently found to be lymphangioma after a partial gastrectomy . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
71,
76
]
} | {
"id": "C0024221",
"name": "lymphangioma",
"pos": [
162,
174
]
} |
the improvement of clinical findings and disappearance of auto-antibodies seen after stopping inh confirmed the diagnosis as inh-induced lupus . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
19,
36
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
112,
121
]
} |
1 ) hospital administrator 's knowledge of importance and necessity for hic ( hospital infection control ) 2 ) supporting hic administratively 3 ) constituting infection control committee and role of icc 4 ) developing an educational program and providing a work manual for the hospital infection control staff 5 ) educating and informing medical staff about hospital infection 6 ) surveillance for hospital infection 7 ) developing patient care technique 8 ) controlling the hospital environment 9 ) executing regular health examinations of all medical staff 10 ) recruiting the medical staff sufficiently three rankings of response rate about 32 elements are as follows : 1 ) hiring a full time staff member for the hic ( 66 % ) 2 ) establishing a hospital policy and standards for the hic ( 66 % ) 3 ) activating the infection control committee and taking administrative action to support the icc ( 63 % ) in addition the rankings of importance score by likert 5 scale are as follows : 1 ) washing hands scrupulously ( 4.88 ) 2 ) nurses participation as key members of the icc ( 4.75 ) 3 ) reviewing and evaluating all ongoing aseptic techniques ( 4.69 ) in conclusion , first of all , administrative support must be given to hiring a full time staff member and to organization of infection control committee for the hic in korea . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
87,
96
]
} | {
"id": "C0205721",
"name": "hospital infection",
"pos": [
399,
417
]
} |
since endogenous circulating levels of atrial natriuretic peptides are elevated during volume expansion and since atrial natriuretic peptides have been shown to blunt or block the vasoconstrictive effects of various pharmacologic agents , we examined the effect of atriopeptin ii infusion on contrast medium-induced alterations in renal blood flow . | nichd_parent_of | {
"id": "C1254351",
"name": "pharmacologic agents",
"pos": [
216,
236
]
} | {
"id": "C0009924",
"name": "contrast medium",
"pos": [
292,
307
]
} |
these procedures include ( 1 ) the cryosurgical detachment operation for treating several tears with individual , permanent plugs and ( 2 ) the balloon operation for single-tear detachments , with a temporary plug ; | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
6,
16
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
152,
161
]
} |
papillary colorimetry is a qualitative and quantitative diagnostic method that defines the displacement of the temporal and nasal color ranges on the x ; y plane of the german industrial standard ( din ) color chart . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
43,
55
]
} | {
"id": "C1514721",
"name": "ranges",
"pos": [
136,
142
]
} |
the occurrence of circulating immunological complexes was investigated in 25 children with uveitis ( 11 with an anterior and 14 with posterior uveitis ) . | nichd_parent_of | {
"id": "C0042164",
"name": "uveitis",
"pos": [
91,
98
]
} | {
"id": "C0042167",
"name": "posterior uveitis",
"pos": [
133,
150
]
} |
this nephropathy was characterized , clinically , by heavy proteinuria or the nephrotic syndrome and a rapid progression to end-stage chronic renal failure and , pathologically , by an aggressive form of focal segmental glomerulosclerosis . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
5,
16
]
} | {
"id": "C0027726",
"name": "nephrotic syndrome",
"pos": [
78,
96
]
} |
this nephropathy was characterized , clinically , by heavy proteinuria or the nephrotic syndrome and a rapid progression to end-stage chronic renal failure and , pathologically , by an aggressive form of focal segmental glomerulosclerosis . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
5,
16
]
} | {
"id": "C0022661",
"name": "end-stage",
"pos": [
124,
133
]
} |
this nephropathy was characterized , clinically , by heavy proteinuria or the nephrotic syndrome and a rapid progression to end-stage chronic renal failure and , pathologically , by an aggressive form of focal segmental glomerulosclerosis . | nichd_parent_of | {
"id": "C0022658",
"name": "nephropathy",
"pos": [
5,
16
]
} | {
"id": "C0017668",
"name": "focal",
"pos": [
204,
209
]
} |
( 2 ) disorders with a loss of multiple peroxisomal functions ( rhizomelic chondrodysplasia punctata and zellweger-like syndrome ; | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
6,
15
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
120,
128
]
} |
a novel procedure was developed for evaluating aromatase inhibitors using human enzyme in a rodent model . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
8,
17
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
36,
46
]
} |
an in vivo procedure for evaluating local effects of alpha-adrenoceptor stimuli on the lower urinary tract was developed in anesthetized dogs . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
11,
20
]
} | {
"id": "C0220825",
"name": "evaluating",
"pos": [
25,
35
]
} |
in summary , transbronchial lung biopsies have provided prompt ( within 24 hours ) serial diagnostic information that has guided successful treatment of infection ( cytomegalovirus , aspergillosis , and pneumocystis ) and rejection . | nichd_parent_of | {
"id": "C0009450",
"name": "infection",
"pos": [
153,
162
]
} | {
"id": "C0004030",
"name": "aspergillosis",
"pos": [
183,
196
]
} |
the most common underlying diseases were neoplasia ( 12 ) , diabetes with stroke ( 4 ) , neurosurgical and vascular procedures ( 4 ) , rheumatoid arthritis ( 2 ) , burns ( 2 ) , cor pulmonale ( 1 ) , and hypertension ( 1 ) . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
27,
35
]
} | {
"id": "C0027651",
"name": "neoplasia",
"pos": [
41,
50
]
} |
treatment of stroke or transient ischemic attacks should be initiated quickly as the risk of recurrence is highest immediately following the signal event . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
13,
19
]
} | {
"id": "C0007787",
"name": "transient ischemic attacks",
"pos": [
23,
49
]
} |
while the evidence for decreasing the risks of coronary disease , congestive heart failure , renal insufficiency , or total mortality is not present , such evidence does exist in younger patients with more severe hypertension . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
6,
9
]
} | {
"id": "C0018802",
"name": "congestive heart failure",
"pos": [
66,
90
]
} |
24 healthy infants with a sibling who had died from sudden infant death syndrome ( sids ) ; | nichd_parent_of | {
"id": "C0011065",
"name": "died",
"pos": [
42,
46
]
} | {
"id": "C0038644",
"name": "sudden infant death syndrome",
"pos": [
52,
80
]
} |
new insights in the structure of the hepatitis b virus ( hbv ) as well as in the immune response mechanism of the organism permit by serological testing a clear definition of the replicative state of the virus . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
114,
122
]
} | {
"id": "C0042776",
"name": "virus",
"pos": [
204,
209
]
} |
some features differed with age to a greater extent in the dorsal portion of the avcn : there were decreases in the length of terminals on bushy cells , and in the percentage of soma surface apposed by terminals , and increases in the incidence of neurons contacted by myelinated axons , in mean synaptic vesicle density , and in the amount of lipofuscin in bushy cells . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
5,
13
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
116,
122
]
} |
glycosaminoglycans , which occur in most organisms from bacteria to vertebrates , appear to be present in all amyloid deposits regardless of the protein involved . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
41,
50
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
56,
64
]
} |
ct scan showed intracerebral hematoma in the left occipital lobe , large hematoma in the left lateral ventricle and subdural hematoma in the interhemispheric region . | nichd_parent_of | {
"id": "C0018944",
"name": "hematoma",
"pos": [
29,
37
]
} | {
"id": "C0018946",
"name": "subdural hematoma",
"pos": [
116,
133
]
} |
it was shown that the bilateral injection of apomorphine or ( + ) 3ppp ( 0.1 , 0.5 and 1.0 nmol for each compound ) into the ventral tegmental area produced behavioural and ecog sleep , accompanied by a statistically-significant increase in ecog total spectrum power . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioural",
"pos": [
157,
168
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
178,
183
]
} |
the diagnostic methods with the best results are ultrasonography and ct scanning , although a checkup after the event showed that straightforward x-ray of the chest , if correctly interpreted , may be enough . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic methods",
"pos": [
4,
22
]
} | {
"id": "C0041618",
"name": "ultrasonography",
"pos": [
49,
64
]
} |
the paper presents the clinical findings in 18 patients in whom the diagnosis of thyrotoxicosis was established at the age of 65 or later . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
23,
40
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
68,
77
]
} |
two weeks later an erythema of 8 cm in diameter , spreading peripherally as well as painful inguinal lymphadenitis developed at the site of the bite with transient arthralgia and myalgia in the region of the waist and left lower limb . | nichd_parent_of | {
"id": "C0030193",
"name": "painful",
"pos": [
84,
91
]
} | {
"id": "C0003862",
"name": "arthralgia",
"pos": [
164,
174
]
} |
two weeks later an erythema of 8 cm in diameter , spreading peripherally as well as painful inguinal lymphadenitis developed at the site of the bite with transient arthralgia and myalgia in the region of the waist and left lower limb . | nichd_parent_of | {
"id": "C0030193",
"name": "painful",
"pos": [
84,
91
]
} | {
"id": "C0231528",
"name": "myalgia",
"pos": [
179,
186
]
} |
the most common type of arrhythmia among the patients under 5 was intraventricular conduction defects , whilst in the age group of 5-10 were sinus tachycardia and intraventricular conduction defects , and in the age group of 10-15 was first degree a-v block . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
24,
34
]
} | {
"id": "C0085614",
"name": "first degree a-v block",
"pos": [
235,
257
]
} |
the optimal recognition of gynecological diseases in childhood and adolescence requires gynecological examination with empathy and subtility . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
53,
62
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
67,
78
]
} |
the analysis of immunoglobulin and t-cell receptor gene structure as well as the analysis of chromosomal translocations has been of great value in defining the lineage of neoplasms , determining the clonality of abnormal lymphocyte proliferations , diagnosis and monitoring of lymphoid malignancies and determining the state of maturation of b- and t-cells . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
171,
180
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
286,
298
]
} |
patients having had a history of pain for at least 6 months were considered to have 'chronic pain , ' while those who had no history of chronic pain were grouped as 'acute pain ' patients . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
33,
37
]
} | {
"id": "C0150055",
"name": "chronic pain",
"pos": [
136,
148
]
} |
vasculitis is an inflammatory involvement with or without necrosis of blood vessels and the predominant feature of a large number of different diseases and syndromes in childhood . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
143,
151
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
156,
165
]
} |
the clinical and histologic character of these neoplasms differentiates them from kaposi 's sarcoma , hemangioendothelioma , and from conventional juvenile hemangioma . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
47,
56
]
} | {
"id": "C0018915",
"name": "hemangioendothelioma",
"pos": [
102,
122
]
} |
for long oligomers , the characteristics of the terminal regions [ length and axial profile of c+n ( a ) ] do not vary with n and , by inference , also pertain to the polyion under the same conditions . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
25,
40
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
67,
73
]
} |
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