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the cytologic appearance and immunologic phenotype of the tumor cells suggest that this malignancy represents a recurrence of his original tumor .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 58, 63 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 88, 98 ] }
i report that particular features can be related to particular components , for example , oscillations depend mainly on population growth and the generation gap of the disease , while estimates of the effect of potential control strategies such as vaccination or culling can be related directly to assumptions concerning the infection term and the way it changes with population density .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 168, 175 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 325, 334 ] }
[ co-carcinogens of the initiation- ( or tumor- ) promoter type as cancer risk factors . a current problem of environmental carcinogenesis and experimental analysis of a typical etiologic model situation ] .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 41, 46 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 67, 73 ] }
the daily hemorrhage into the hematoma cavity did not correlate clearly with the maximum breadth of subdural hematoma in ct scans or carotid angiograms .
nichd_parent_of
{ "id": "C0018944", "name": "hematoma", "pos": [ 30, 38 ] }
{ "id": "C0018946", "name": "subdural hematoma", "pos": [ 100, 117 ] }
the experiments were designed to explore the role of retinal inputs compared with that of the behavioral state in the modulation of the output of thalamic lateral geniculate neurons during sleep and wakefulness in cats with intact visual pathways .
nichd_parent_of
{ "id": "C0004927", "name": "behavioral", "pos": [ 94, 104 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 189, 194 ] }
the occurrence of di after an hypoxic/ischemic insult may represent midbrain death and seems to be a clinically useful sign in the diagnosis of brain death in children .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 77, 82 ] }
{ "id": "C0006110", "name": "brain death", "pos": [ 144, 155 ] }
since the procedure is simple , well tolerated and bears little risk , and the therapeutical result is reasonably good for advanced cases , we feel justified in recommending this treatment in the form of a prospective study at least for cases in which direct surgical establishment of a catheter for implantation of a pump system is not performed .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 10, 19 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 259, 267 ] }
a more conservative surgical procedure with the aim of preserving fertility in younger women , who wish to have children , requires the secure evidence of stage ia and proof of a tumor with a low malignancy grade , given by an experienced histologist .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 179, 184 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 196, 206 ] }
it is the first-line treatment of choice in all patients with stage iii or iv of disease and where tumor deposits larger than 2 cm remain in the abdominal cavity after surgery .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 81, 88 ] }
{ "id": "C0027651", "name": "tumor", "pos": [ 99, 104 ] }
microbial organisms isolated from deep infection foci were not consistently identical with pathogens previously identified in wound drainage fluid .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 10, 19 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 91, 100 ] }
however , current evidence favors respiratory dysfunction as the primary mechanism of death in most sids babies .
nichd_parent_of
{ "id": "C0011065", "name": "death", "pos": [ 86, 91 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 100, 104 ] }
cross-reactions occurred with antibodies in the sera of patients with other parasitic infections , especially other larval cestodes and filarial parasites .
nichd_parent_of
{ "id": "C0747256", "name": "parasitic", "pos": [ 76, 85 ] }
{ "id": "C0010678", "name": "larval cestodes", "pos": [ 116, 131 ] }
a procedure was developed for investigation of the penicillins either in the pure state or in dosage forms .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 2, 11 ] }
{ "id": "C0220825", "name": "investigation", "pos": [ 30, 43 ] }
we conducted a long-term study of the circadian rhythms of temperature and sleep in the rat after lesions of the suprachiasmatic nuclei ( scn ) .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 3, 12 ] }
{ "id": "C0037313", "name": "sleep", "pos": [ 75, 80 ] }
data from the national survey of family growth conducted by the national center for health statistics were used to investigate the social correlates of breast feeding during the periods 1970-72 and 1973-75 to determine if these factors were related to the reversal in the breast feeding trend .
nichd_parent_of
{ "id": "C0004927", "name": "conducted", "pos": [ 47, 56 ] }
{ "id": "C0006147", "name": "breast feeding", "pos": [ 272, 286 ] }
the renal disease was usually associated with the nephrotic syndrome or oedema but was asymptomatic throughout in one patient .
nichd_parent_of
{ "id": "C0022658", "name": "renal disease", "pos": [ 4, 17 ] }
{ "id": "C0027726", "name": "nephrotic syndrome", "pos": [ 50, 68 ] }
lesions of letterer-siwe disease , hand-schuller-christian disease , multiple eosinophilic granuloma , and solitary eosinophilic granuloma resolved at comparable rates .
nichd_parent_of
{ "id": "C0019621", "name": "hand-schuller-christian disease", "pos": [ 35, 66 ] }
{ "id": "C0014461", "name": "eosinophilic granuloma", "pos": [ 116, 138 ] }
this review evaluates the role of local tissue factors - anatomical , physiological , physical and immunological - in this process .
nichd_parent_of
{ "id": "C0220825", "name": "evaluates", "pos": [ 12, 21 ] }
{ "id": "C0031809", "name": "physical", "pos": [ 86, 94 ] }
the prognostic value of different pretreatment laboratory and clinical findings at diagnosis was assessed in a series of 141 patients with generalized non-hodgkin 's lymphoma .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 62, 79 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 83, 92 ] }
the laboratory examinations included the following tests : cognitive capacity ( 4 tests ) , audiometry , speech understanding , visual tests , vibration threshold , posture control , reaction and movement time , tapping rate , leg extension velocity , anthropometric measurements , skin measurements , bone mineral density , physiotherapist 's examination , physician 's examination , blood analyses , isometric strength of muscles ( 5 muscles ) , anaerobic power , aerobic power and anaerobic threshold .
nichd_parent_of
{ "id": "C0022885", "name": "tests", "pos": [ 51, 56 ] }
{ "id": "C0018941", "name": "blood analyses", "pos": [ 385, 399 ] }
intraglial uptake of extravasated serum proteins has been hypothesized to be an edema-resolving mechanism in brain edema .
nichd_parent_of
{ "id": "C0013604", "name": "edema", "pos": [ 80, 85 ] }
{ "id": "C0006114", "name": "brain edema", "pos": [ 109, 120 ] }
identification of elevated serum triglycerides ( tg ) in two tumor-bearing ( tb ) animal models and recently reported in humans with cancer may be a part of this dysfunctional state .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 61, 66 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 133, 139 ] }
although the results showed that sputum clearing -- that is , changing from purulent to mucoid -- largely depended on the pathogenic organism isolated , this was not exclusively the case and in some cases sputum growing sensitive organisms failed to clear whereas clearing occurred in other samples containing resistant organisms or no obvious pathogens .
nichd_parent_of
{ "id": "C0029235", "name": "organisms", "pos": [ 230, 239 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 344, 353 ] }
for the past few years , two-dimensional diagnostic ultrasound methods have become available to veterinary medicine .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic", "pos": [ 41, 51 ] }
{ "id": "C0041618", "name": "ultrasound", "pos": [ 52, 62 ] }
this cell line was transplantable in athymic nude mice to form progressive tumors which had histology similar to that of the original cancer ( papillotubular adenocarcinoma ) .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 75, 81 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 134, 140 ] }
[ multiple chromosome aberrations in 3 generations of a family and down 's syndrome resulting from partial trisomy of chromosome 21 ( q21 -- q22 ) ] .
nichd_parent_of
{ "id": "C0008625", "name": "chromosome aberrations", "pos": [ 11, 33 ] }
{ "id": "C0013080", "name": "down 's", "pos": [ 67, 74 ] }
in adults and in children above 3 years of age , the villi were usually shaped like fingers or leaves , but in infants , ridge-shaped villi predominated .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 17, 25 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 111, 118 ] }
to answer the many questions about this procedure , it is appropriate to encourage that carefully designed randomized protocols comparing surgical revascularization and percutaneous transluminal dilatation in patients with similar clinical and epidemiologic criteria be developed .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 40, 49 ] }
{ "id": "C0543467", "name": "surgical", "pos": [ 138, 146 ] }
one of the components of nuclear grading , the size or cross-sectional area of cancerous nuclei , might by itself be a determinant of biologic behavior in rcc .
nichd_parent_of
{ "id": "C0006826", "name": "cancerous", "pos": [ 79, 88 ] }
{ "id": "C0007134", "name": "rcc", "pos": [ 155, 158 ] }
the examination of the relative areas of cancerous nuclei , herein termed nuclear sizing , appears to be a prognostic discriminant in primary rcc .
nichd_parent_of
{ "id": "C0006826", "name": "cancerous", "pos": [ 41, 50 ] }
{ "id": "C0007134", "name": "rcc", "pos": [ 142, 145 ] }
the analysis of immediate results of 271 correcting operations for congenital hydronephrosis in children has shown that the operations may be followed by such complications at the early postoperative period as aggravation of pyelonephritis ( 10 patients ) , urinal fistulas ( 8 patients ) , urinary leakage ( 4 patients ) , paraureteral abscesses ( 3 cases ) as well as postoperative bleedings ( 5 cases ) and suppuration of the operative wound ( 4 cases ) .
nichd_parent_of
{ "id": "C0009566", "name": "complications", "pos": [ 159, 172 ] }
{ "id": "C0032788", "name": "postoperative bleedings", "pos": [ 370, 393 ] }
clinical signs observed by day 7 in pigs given 10 mg/kg body weight were weakness , inactivity , anorexia , rough hair coats , and reduced body weights .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C3714552", "name": "weakness", "pos": [ 73, 81 ] }
clinical signs observed by day 7 in pigs given 10 mg/kg body weight were weakness , inactivity , anorexia , rough hair coats , and reduced body weights .
nichd_parent_of
{ "id": "C3540840", "name": "clinical signs", "pos": [ 0, 14 ] }
{ "id": "C0003123", "name": "anorexia", "pos": [ 97, 105 ] }
in the zone of exposure , foci of `` '' continued '' '' growth attributed by the authors to the clonal composition to tumor as well as foci of `` '' newly-developed '' '' carcinoma in situ accounted for by multicentricity of cancer in the larynx were observed against the background of highly-pronounced radiation injuries .
nichd_parent_of
{ "id": "C0027651", "name": "o tum", "pos": [ 116, 121 ] }
{ "id": "C0006826", "name": "of ca", "pos": [ 222, 227 ] }
[ individual variability in the subthalamic region of children and adolescents in relation to stereotaxic coordinates ] .
nichd_parent_of
{ "id": "C0027361", "name": "individual", "pos": [ 2, 12 ] }
{ "id": "C0008059", "name": "children", "pos": [ 54, 62 ] }
from our experience , four types of cancerous lesions seem prone to being missed during gross examination , namely : any small cancer with a consistency similar to that of the parenchyma of the organ in which the tumor is located , superficially invasive carcinoma , scar cancer and a radiologically occult lung cancer in the presence of a coexisting radiologically demonstrable lesion .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 213, 218 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 312, 318 ] }
the data in 104 comatose children were analysed , neonates and those with head injury being excluded .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 25, 33 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 50, 58 ] }
later on roentgen examination was introduced and later still microscopic diagnosis , more advanced diagnostic methods , e.g . endoscopy , ultrasound , isotope examination and advanced microscopic diagnosis and computerized tomography .
nichd_parent_of
{ "id": "C0430022", "name": "diagnostic methods", "pos": [ 99, 117 ] }
{ "id": "C0041618", "name": "ultrasound", "pos": [ 138, 148 ] }
the most significant feature of these fatal children diseases was the sharp contrast between the causes peculiar to neonates ( perinatal ) on the one hand and those common among post-neonates and pre-school-age children on the other .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 44, 52 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 183, 191 ] }
enlargement of the tendon as well as the muscle was a frequent finding , but a normal tendinous insertion did not preclude the diagnosis of orbital myositis .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 63, 70 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 127, 136 ] }
correlation with history , clinical findings , and therapeutic response must be considered in making the diagnosis .
nichd_parent_of
{ "id": "C0037088", "name": "clinical findings", "pos": [ 27, 44 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 105, 114 ] }
when sustained vt was induced from both sites ( 51 % ) , it was usually of the same morphologic characteristics , axis and cycle length .
nichd_parent_of
{ "id": "C1521970", "name": "characteristics", "pos": [ 96, 111 ] }
{ "id": "C1444754", "name": "length", "pos": [ 129, 135 ] }
histologically the neoplasms were tubular adenomas with small focal carcinomatous changes restricted to the gastric tumor .
nichd_parent_of
{ "id": "C0027651", "name": "neoplasms", "pos": [ 19, 28 ] }
{ "id": "C0006826", "name": "carcinomatous", "pos": [ 68, 81 ] }
during the arrest and over the subsequent 48 hours , malignant tachyarrhythmias were manifested by torsade de pointe and repeated episodes of ventricular fibrillation .
nichd_parent_of
{ "id": "C0080203", "name": "tachyarrhythmias", "pos": [ 63, 79 ] }
{ "id": "C0040479", "name": "torsade de pointe", "pos": [ 99, 116 ] }
candida arthritis is an uncommon cause of infectious arthritis that may occur in seriously ill or immunosuppressed patients .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 8, 17 ] }
{ "id": "C0003869", "name": "infectious arthritis", "pos": [ 42, 62 ] }
qualitative amniotic fluid volume was designated as normal if at least one pocket of amniotic fluid measuring 1 cm in broadest diameter was identified .
nichd_parent_of
{ "id": "C0205556", "name": "qualitative", "pos": [ 0, 11 ] }
{ "id": "C0205396", "name": "identified", "pos": [ 140, 150 ] }
mammary tumor development led to early death and precluded development of tumors of the nervous system , which require a longer latency period .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 8, 13 ] }
{ "id": "C0027766", "name": "of tumors", "pos": [ 71, 80 ] }
in an intensive study of a rural area , the authors found that 4 % of the population over age 40 was actively psychotic , with diagnoses of schizophrenia , schizoaffective disorder , and bipolar disorder .
nichd_parent_of
{ "id": "C0004936", "name": "psychotic", "pos": [ 110, 119 ] }
{ "id": "C0005586", "name": "bipolar disorder", "pos": [ 187, 203 ] }
characteristics of dcc associated with higher rates of disease among children were the presence of young , non-bowel trained children , staff who both diapered infants and prepared food on a regular basis , dcc for profit management , and dcc whose only guidelines were provided by the state .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 69, 77 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 160, 167 ] }
there was no significant difference seen in the log plasma concentration-evoked compound electromyogram ( ecemg ) response between 20-80 % paralysis for adults , children , infants , and five of the seven neonates studied .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 162, 170 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 173, 180 ] }
there was no significant difference seen in the log plasma concentration-evoked compound electromyogram ( ecemg ) response between 20-80 % paralysis for adults , children , infants , and five of the seven neonates studied .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 162, 170 ] }
{ "id": "C0021289", "name": "neonates", "pos": [ 205, 213 ] }
the blood-gas partition coefficients in children ( 1.28 , 1.78 , 2.39 , 15.0 , respectively ) , which were intermediate between those in newborns ( p less than 0.005 ) and those in adults ( p less than 0.005 ) , were not significantly different from those in elderly adults ( 1.29 , 1.79 , 2.41 , 15.0 , respectively ) .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 40, 48 ] }
{ "id": "C0021289", "name": "newborns", "pos": [ 137, 145 ] }
the increased risk for patients over 70 years of age was based on the presence of two or more preoperative diseases , the occurrence of emergency surgery and the occurrence of postoperative complications , especially surgical infection .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 107, 115 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 226, 235 ] }
these included seven cases of letterer-siwe ( ls ) disease , four cases of hand-schuller-christian disease , and four cases of eosinophilic granuloma seen at ramathibodi hospital , bangkok , thailand , during the years 1970 to 1981 .
nichd_parent_of
{ "id": "C0019621", "name": "hand-schuller-christian disease", "pos": [ 75, 106 ] }
{ "id": "C0014461", "name": "eosinophilic granuloma", "pos": [ 127, 149 ] }
laboratory studies disclosed the lesions were due to mycobacterium gordonae , an organism commonly ignored as a pathogen .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 81, 89 ] }
{ "id": "C0450254", "name": "pathogen", "pos": [ 112, 120 ] }
ultrasound gave an accurate diagnosis of 85 % in infants with germinal layer haemorrhage , 92 % in intraventricular haemorrhage , and 97 % in intracerebral haemorrhage .
nichd_parent_of
{ "id": "C0019080", "name": "haemorrhage", "pos": [ 77, 88 ] }
{ "id": "C2937358", "name": "intracerebral haemorrhage", "pos": [ 142, 167 ] }
the findings suggest a relationship between depression and some of the anxiety disorders , and between adult panic disorder and agoraphobia and transmission of anxiety disorders to children .
nichd_parent_of
{ "id": "C0003469", "name": "anxiety disorders", "pos": [ 71, 88 ] }
{ "id": "C0001818", "name": "agoraphobia", "pos": [ 128, 139 ] }
our results demonstrate that the incidence of lgs after 6 years of age does not necessarily imply a lower frequency of organic antecedents , or better neuropsychomotor development up to the onset of the syndrome or the presence of a higher rate of nonspecific seizures ( generalized or partial seizures , and mainly those with elaborate symptomatology ) .
nichd_parent_of
{ "id": "C0036572", "name": "seizures", "pos": [ 260, 268 ] }
{ "id": "C0751495", "name": "partial seizures", "pos": [ 286, 302 ] }
alcoholism , brain damage following head injury , osteo-arthritis , cervical spondylosis , rheumatoid arthritis and osteoporosis may be complicating factors in the management of odontoid fractures .
nichd_parent_of
{ "id": "C0003864", "name": "arthritis", "pos": [ 56, 65 ] }
{ "id": "C0003873", "name": "rheumatoid", "pos": [ 91, 101 ] }
thirteen siblings of children dying of sids , nine near miss sids infants and nine preterm infants with apnoea persisting beyond 40 weeks post conceptual age were monitored from a mean age of 15 days to a mean of 10 months .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 21, 29 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 91, 98 ] }
the metals zinc , iron , copper , manganese , calcium , magnesium , potassium and sodium were analysed in the livers of 67 australian infants who had died from sudden infant death syndrome ( sids ) and 29 infants who had died from other causes ( non-sids ) .
nichd_parent_of
{ "id": "C0011065", "name": "died", "pos": [ 150, 154 ] }
{ "id": "C0038644", "name": "sids", "pos": [ 250, 254 ] }
the possible biological role of heparin and/or mast cells in the surveillance of the organism against some pathogens is discussed in the light of these and other findings .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 85, 93 ] }
{ "id": "C0450254", "name": "pathogens", "pos": [ 107, 116 ] }
ventricular arrhythmias , especially ventricular fibrillation , are assumed to be a main cause of sudden death during the first 24 h of acute myocardial infarction .
nichd_parent_of
{ "id": "C0085612", "name": "ventricular arrhythmias", "pos": [ 0, 23 ] }
{ "id": "C0042510", "name": "ventricular fibrillation", "pos": [ 37, 61 ] }
thus identification of the anomalous origin of the left coronary artery from the pulmonary trunk appears to be the only reliable echocardiographic finding in this condition , and contrast cineaortography remains necessary in patients in whom the diagnosis is suspected clinically or electrocardiographically .
nichd_parent_of
{ "id": "C0037088", "name": "finding", "pos": [ 147, 154 ] }
{ "id": "C0011900", "name": "diagnosis", "pos": [ 246, 255 ] }
the effectiveness of administration of glycopyrrolate 5 and 10 micrograms kg-1 and atropine 10 and 20 micrograms kg-1 i.v . immediately before the induction of anaesthesia , to prevent arrhythmia and bradycardia following repeated doses of suxamethonium in children , was studied .
nichd_parent_of
{ "id": "C0003811", "name": "arrhythmia", "pos": [ 185, 195 ] }
{ "id": "C0428977", "name": "bradycardia", "pos": [ 200, 211 ] }
it is noted that the 15 % increase in diagnostic accuracy achieved in the present study is comparable to the proportion of breast carcinoma patients in whom disseminated disease develops despite their axillary lymph nodes being reported as tumour-free at the time of surgery .
nichd_parent_of
{ "id": "C0012634", "name": "disease", "pos": [ 170, 177 ] }
{ "id": "C0027651", "name": "tumour", "pos": [ 240, 246 ] }
in addition , one patient with diffuse scleroderma revealed a dense speckled , and two patients with the crest syndrome a discrete speckled , epidermal nuclear staining pattern by c + dif .
nichd_parent_of
{ "id": "C0036421", "name": "diffuse scleroderma", "pos": [ 31, 50 ] }
{ "id": "C0206138", "name": "crest syndrome", "pos": [ 105, 119 ] }
the leukemia intergroup study has treated 110 patients with acute nonlymphocytic leukaemia with 'high dose ' cytosine arabinoside remission induction therapy and studied the factors which were related to the outcome of therapy .
nichd_parent_of
{ "id": "C0023418", "name": "study", "pos": [ 24, 29 ] }
{ "id": "C0023467", "name": "acute nonlymphocytic", "pos": [ 60, 80 ] }
the effect of cervical suture on pregnancy outcome was studied in 194 women with a high risk ( approximately 30 % ) of having a late abortion or a preterm delivery .
nichd_parent_of
{ "id": "C0032972", "name": "pregnancy outcome", "pos": [ 33, 50 ] }
{ "id": "C0151526", "name": "preterm delivery", "pos": [ 147, 163 ] }
[ individual variability of the secretion of sex steroids , somatotropic hormone and cortisol in males at puberty ] .
nichd_parent_of
{ "id": "C1522384", "name": "steroids", "pos": [ 49, 57 ] }
{ "id": "C0086582", "name": "males", "pos": [ 97, 102 ] }
it was concluded that the procedure was associated with a very low risk of complication , but that the involvement of normal donors in such an operation justifies stringent monitoring .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 26, 35 ] }
{ "id": "C0543467", "name": "operation", "pos": [ 143, 152 ] }
birth weight , length , head circumference and bilirubin level in indian newborns in the sioux lookout zone , northwestern ontario .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 15, 21 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 24, 42 ] }
the norms for birth weight , length , head circumference and bilirubin level for native newborns have not been available .
nichd_parent_of
{ "id": "C1444754", "name": "length", "pos": [ 29, 35 ] }
{ "id": "C0262499", "name": "head circumference", "pos": [ 38, 56 ] }
malignant peripheral nerve sheath tumors are uncommon sarcomas of schwann cell or fibroblastic derivation which occasionally show histologic evidence of focal divergent differentiation to rhabdomyosarcoma , osteosarcoma , chondrosarcoma , angiosarcoma , epithelial elements , or a combination thereof .
nichd_parent_of
{ "id": "C1261473", "name": "sarcomas", "pos": [ 54, 62 ] }
{ "id": "C0029463", "name": "osteosarcoma", "pos": [ 207, 219 ] }
examination of the distribution of nse in a wide range of tumors ( n = 55 ) showed that it is relatively specific for neurons and neuroendocrine tumors .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 58, 64 ] }
{ "id": "C0206754", "name": "neuroendocrine tumors", "pos": [ 130, 151 ] }
a quantitative immunoassay procedure has been constructed to evaluate levels of ductal carcinoma antigen recognized by murine mcab f36/22 .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 27, 36 ] }
{ "id": "C0220825", "name": "evaluate", "pos": [ 61, 69 ] }
whole-body hyperthermia , spontaneous or artificially induced , can produce severe lesions that have been best described in humans : necropsies , of fatal cases of heatstroke or of individuals treated in the 1940s by hyperpyrexia , have demonstrated important lesions in the central nervous system , liver , kidney , heart , adrenal , testis , and bone marrow .
nichd_parent_of
{ "id": "C0015967", "name": "hyperthermia", "pos": [ 11, 23 ] }
{ "id": "C0392676", "name": "hyperpyrexia", "pos": [ 217, 229 ] }
these data are to be included subsequently in the tumor record of each cancer patient in the state , thus enhancing the value and usefulness of the connecticut tumor registry .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 50, 55 ] }
{ "id": "C0006826", "name": "cancer", "pos": [ 71, 77 ] }
the following injuries presented particular problems : displaced intra-articular fractures , salter i distal phalangeal fractures due to crushing injuries , displaced subcondylar fractures , and open fractures .
nichd_parent_of
{ "id": "C0016658", "name": "fractures", "pos": [ 81, 90 ] }
{ "id": "C0016662", "name": "open", "pos": [ 195, 199 ] }
triplane distal tibial fractures can occur as two- , three- , or four-part fractures with or without a fibular fracture .
nichd_parent_of
{ "id": "C0016658", "name": "fractures", "pos": [ 23, 32 ] }
{ "id": "C0149699", "name": "fibular fracture", "pos": [ 103, 119 ] }
the procedure is used to choose among competing therapies on the basis of precedence rules .
nichd_parent_of
{ "id": "C0184661", "name": "procedure", "pos": [ 4, 13 ] }
{ "id": "C0087111", "name": "therapies", "pos": [ 48, 57 ] }
[ how shall we tell the children ? ( death of a newborn infant and its impact on his siblings ) ] .
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 24, 32 ] }
{ "id": "C0021289", "name": "newborn", "pos": [ 48, 55 ] }
longevity of the implants is improved by slowing down the occasional rapid head shaking characteristic of cats , which tends to tear out implanted electrodes , by means of a small weight attached by a bar to the head .
nichd_parent_of
{ "id": "C1521970", "name": "characteristic", "pos": [ 88, 102 ] }
{ "id": "C0005910", "name": "weight", "pos": [ 180, 186 ] }
the growth of lung volumes affected by physical performance capacity in boys and girls during childhood and adolescence .
nichd_parent_of
{ "id": "C0231335", "name": "childhood", "pos": [ 94, 103 ] }
{ "id": "C0001578", "name": "adolescence", "pos": [ 108, 119 ] }
underlying diseases or prior splenectomy are predisposing factors for severe infection with a potentially fatal outcome .
nichd_parent_of
{ "id": "C0012634", "name": "diseases", "pos": [ 11, 19 ] }
{ "id": "C0009450", "name": "infection", "pos": [ 77, 86 ] }
when the data were further analyzed based on the birth weight , tobramycin kinetics changed during the second study compared to the first study in very low birth weight infants .
nichd_parent_of
{ "id": "C0005612", "name": "birth weight", "pos": [ 49, 61 ] }
{ "id": "C0282666", "name": "very low birth weight infants", "pos": [ 147, 176 ] }
sendai virus , m. pulmonis , p. aeruginosa and mhv were positive in 51.7 to 23.6 % of the colonies , and tyzzer 's organism , b. bronchiseptica and probably sda virus were also detected in more than 10 % of the rat colonies .
nichd_parent_of
{ "id": "C0029235", "name": "organism", "pos": [ 115, 123 ] }
{ "id": "C0042776", "name": "virus", "pos": [ 161, 166 ] }
chromosomal constitution of the hybrid tumors indicate that as a rule , the expression of malignancy correlates with elimination of the morphologically normal chromosome pairs no 1 , 4 , 6 , 8 .
nichd_parent_of
{ "id": "C0027651", "name": "tumors", "pos": [ 39, 45 ] }
{ "id": "C0006826", "name": "malignancy", "pos": [ 90, 100 ] }
we attempted to determine whether all cases of awta ( anirida-wilms tumor association ) or any of the following groups of patients show 11p deletion : cases of wilms tumor with congenital abnormalities other than aniridia , those without any congenital abnormalities , tumor itself in cases of wilms tumor without constitutional 11p deletion and cases of aniridia or hemihypertrophy without wilms tumor .
nichd_parent_of
{ "id": "C0000768", "name": "congenital abnormalities", "pos": [ 177, 201 ] }
{ "id": "C0332890", "name": "hemihypertrophy", "pos": [ 367, 382 ] }
we studied a total of 29 index patients including five cases of awta , four cases of wilms tumor with various congenital abnormalities , 16 cases of wilms tumor without other abnormalities , three cases of aniridia in one of which wilms tumor developed later and a case of hemihypertrophy .
nichd_parent_of
{ "id": "C0000768", "name": "abnormalities", "pos": [ 121, 134 ] }
{ "id": "C0332890", "name": "hemihypertrophy", "pos": [ 273, 288 ] }
the pattern of cancer occurrence resembles that seen in other middle-eastern populations in the frequency of respiratory cancer and lymphomas , and the apparent deficit of cervix cancer .
nichd_parent_of
{ "id": "C0006826", "name": "cancer", "pos": [ 15, 21 ] }
{ "id": "C0024299", "name": "lymphomas", "pos": [ 132, 141 ] }
cellular hypersensitivity was less common in membranous nephropathy , membranoproliferative ( i-iii ) glomerulonephritis , iga nephropathy and lupus nephritis .
nichd_parent_of
{ "id": "C0017658", "name": "glomerulonephritis", "pos": [ 102, 120 ] }
{ "id": "C0017661", "name": "iga nephropathy", "pos": [ 123, 138 ] }
twelve children were found to have the disorder and they underwent further assessment in order to establish any etiological factors or anatomical abnormalities .
nichd_parent_of
{ "id": "C0012634", "name": "disorder", "pos": [ 39, 47 ] }
{ "id": "C0302142", "name": "anatomical abnormalities", "pos": [ 135, 159 ] }
these results highlight two related but incompletely understood phenomena as follows : 1 ) a functionally truncated krebs cycle in cholesterol-rich tumor mitochondria , and 2 ) a mechanism for providing higher cytoplasmic levels of precursor metabolite intermediates which help sustain deregulated cholesterogenesis in hepatomas and other malignant neoplasms .
nichd_parent_of
{ "id": "C0027651", "name": "tumor", "pos": [ 148, 153 ] }
{ "id": "C0006826", "name": "malignant neoplasms", "pos": [ 339, 358 ] }
no cells stained positively for beta enolase in the control series of neuroblastomas , fibrosarcomas , wilms ' sarcomas , and an osteosarcoma .
nichd_parent_of
{ "id": "C1261473", "name": "sarcomas", "pos": [ 92, 100 ] }
{ "id": "C0029463", "name": "osteosarcoma", "pos": [ 129, 141 ] }
the measurement of tumour ploidy is likely to become a valuable adjunct to the clinical and histopathological assessment of cancers .
nichd_parent_of
{ "id": "C0027651", "name": "tumour", "pos": [ 19, 25 ] }
{ "id": "C0006826", "name": "cancers", "pos": [ 124, 131 ] }
comparison of these data with those obtained in the cat and monkey suggests that a constant feature of eutherian brains is the existence of a subset of efferents from each of the four neocortical sensory systems that is routed so as to provide subcortical limbic structures with modality-specific information .
nichd_parent_of
{ "id": "C1521970", "name": "feature", "pos": [ 92, 99 ] }
{ "id": "C0695347", "name": "modality", "pos": [ 279, 287 ] }
today , the best evidence for the involvement of leukotrienes in human skin disease is psoriasis .
nichd_parent_of
{ "id": "C0037274", "name": "skin disease", "pos": [ 71, 83 ] }
{ "id": "C0033860", "name": "psoriasis", "pos": [ 87, 96 ] }
thirteen children aged 5 months to 4 years were observed during a varicella epidemic in an infants ' hospital ;
nichd_parent_of
{ "id": "C0008059", "name": "children", "pos": [ 9, 17 ] }
{ "id": "C0021270", "name": "infants", "pos": [ 91, 98 ] }
the lead acetate exerts an important action on hypersensitivity reactions whether on rat mast cells degranulation ( immediate hypersensitivity ) or on contact hypersensitivity .
nichd_parent_of
{ "id": "C0020517", "name": "hypersensitivity reactions", "pos": [ 47, 73 ] }
{ "id": "C0020523", "name": "immediate hypersensitivity", "pos": [ 116, 142 ] }