text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
the ecmp was found to be a more sensitive , more easily interpreted , and more consistent means of evaluating the degree of spinal injury than the ecp or the neurologic examination . | nichd_parent_of | {
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castration of males worsened their disease , whereas testosterone treatment of females ameliorated their autoimmune syndrome . | nichd_parent_of | {
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} | {
"id": "C0039082",
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clinical trials evaluating alternative surgical treatments or adjunctive therapy modalities for melanoma patients should incorporate these parameters into their assessment , especially in stage i ( localized ) disease where tumor thickness and the anatomical site of the primary melanoma are dominant prognostic factors . | nichd_parent_of | {
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[ development of a procedure for the determination , evaluation and comparison of wound traces using a digital computer ] . | nichd_parent_of | {
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this finding is of considerable diagnostic importance , and leads support to the theory that discitis is due to bacterial infection . | nichd_parent_of | {
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the quantitative range of the test has been limited to amounts exceeding 425 mg of toluene and concentrations exceeding 69 ppm of toluene in the air because of the physiological presence of hippuric acid in urine . | nichd_parent_of | {
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in 31 wasted infants ( including 4 post-mature children ) and 20 not wasted infants , the ponderal index ( 100 x w/l3 ) was determined and deviation from 'normal ' calculated . | nichd_parent_of | {
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lesion-specific genetic factors in canine congenital heart diseases : patent ductus arteriosus in poodles , defects of the conotruncal septum in the keeshond . | nichd_parent_of | {
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lesion-specific genetic factors in canine congenital heart diseases : patent ductus arteriosus in poodles , defects of the conotruncal septum in the keeshond . | nichd_parent_of | {
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} | {
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in the united states statistics on sexually transmitted diseases ( stds ) , other than gonorrhoea and syphilis , are meagre . | nichd_parent_of | {
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} | {
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in the united states statistics on sexually transmitted diseases ( stds ) , other than gonorrhoea and syphilis , are meagre . | nichd_parent_of | {
"id": "C0036916",
"name": "sexually transmitted diseases",
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} | {
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the result of this procedure depends upon the accuracy in predicting the further growth in order to determine at what age the operation should be performed . | nichd_parent_of | {
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a modified microassay procedure , using triphenyltetrazolium chloride as a germination indicator , was compared with a macroassay method proposed by the world health organization for determining the level of antibodies before and after immunization with group a meningococcal polysaccharide vaccine . | nichd_parent_of | {
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} | {
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this article reviews the current state of knowledge on the viral haemorrhagic fevers that infect man , namely smallpox , chikungunya fever , dengue fever , rift valley fever , yellow fever , crimean haemorrhagic fever , kyasanur forest disease , omsk haemorrhagic fever , argentinian haemorrhagic fever ( junin virus ) , bolivian haemorrhagic fever ( machupo virus ) , lassa fever , haemorrhagic fever with renal syndrome , and marburg and ebola virus diseases . | nichd_parent_of | {
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} | {
"id": "C0035613",
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156,
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} |
this article reviews the current state of knowledge on the viral haemorrhagic fevers that infect man , namely smallpox , chikungunya fever , dengue fever , rift valley fever , yellow fever , crimean haemorrhagic fever , kyasanur forest disease , omsk haemorrhagic fever , argentinian haemorrhagic fever ( junin virus ) , bolivian haemorrhagic fever ( machupo virus ) , lassa fever , haemorrhagic fever with renal syndrome , and marburg and ebola virus diseases . | nichd_parent_of | {
"id": "C0019104",
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59,
77
]
} | {
"id": "C0019099",
"name": "crimean haemorrhagic fever",
"pos": [
191,
217
]
} |
this article reviews the current state of knowledge on the viral haemorrhagic fevers that infect man , namely smallpox , chikungunya fever , dengue fever , rift valley fever , yellow fever , crimean haemorrhagic fever , kyasanur forest disease , omsk haemorrhagic fever , argentinian haemorrhagic fever ( junin virus ) , bolivian haemorrhagic fever ( machupo virus ) , lassa fever , haemorrhagic fever with renal syndrome , and marburg and ebola virus diseases . | nichd_parent_of | {
"id": "C0019104",
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} | {
"id": "C0023092",
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this case documents that recurrent massive hemoptysis can be successfully controlled with repeated use of this procedure and that the simultaneous placement of more than one catheter can be safe and effective therapy that is well tolerated by patients . | nichd_parent_of | {
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analysis of the social behavior revealed that , at both ages , the children assumed differentiable roles in their interactions : the infants `` '' followed '' '' by observing and imitating while the preschoolers `` '' led '' '' by drawing the infants ' attention and by assertive dominance . | nichd_parent_of | {
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} | {
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tumoral colonic lesions were detected in 105 patients with a total of 125 adenomas and 31 cancers . | nichd_parent_of | {
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} | {
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[ transketolase activity as a parameter for the vitamin b1 provision in some dermatoses ( herpes zoster , psoriasis , drug eruptions , excema , and urticaria ) ( author 's transl ) ] . | nichd_parent_of | {
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} | {
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as the usual noninvasive and invasive examination methods proved to be rather inaccurate , a new procedure , the 'lh/hcg test ' , was evaluated . | nichd_parent_of | {
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} | {
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thus a b-cell dependent splenic retention process of dth-c is discussed as the origin of dth unresponsiveness observed after priming with large doses of antigen . | nichd_parent_of | {
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immunopathological studies have shown that a vasculitis is the essential lesion in bs and this might be secondary to immune complexes inducing complement activation and damage . | nichd_parent_of | {
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} | {
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} |
outcomes of pregnancy were examined for 480 women who requested abortions at a jerusalem hospital during the years 1972 to 1975 . | nichd_parent_of | {
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} | {
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} |
antibodies to ribo-nuclease-sensitive ena ( anti-rnp ) occurred in the minority of patients with sle ( 2/72 ) and the mixed connective tissue disease syndrome ( mctd ) . | nichd_parent_of | {
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} | {
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patients were allocated to nine groups : typical ankylosing spondylitis , ankylosing spondylitis with moderate involvement without peripheral arthritis , ankylosing spondylitis with moderate involvement and with peripheral arthritis , juvenile chronic arthritis , reiter 's syndrome , yersinia arthritis , arthropathies of inflammatory bowel disease , psoriatic arthritis , seronegative and seropositive rheumatoid arthritis . | nichd_parent_of | {
"id": "C0003864",
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142,
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} | {
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"name": "psoriatic arthritis",
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} |
intracellular collagen was detected by electron microscopy in 14 sarcomas including six osteogenic sarcomas , three liposarcomas , three malignant fibrous histiocytomas , one pleomorphic rhabdomyosarcoma , and one childhood rhabdomyosarcoma . | nichd_parent_of | {
"id": "C1261473",
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} | {
"id": "C0029463",
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} |
the greatest coefficients of occupational diseases morbidity resulted from : occupational hearing impairments , infectious and invasing diseases , intoxications , pneumoconioses , vibration disease and diseases of skin and mucous membranes . | nichd_parent_of | {
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} | {
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} |
postransplant , a glomerulonephritis histologically and immunologically indistinguishable from iga nephropathy ( berger 's disease ) developed in the absence of any extrarenal manifestations of the henoch-schonlein syndrome . | nichd_parent_of | {
"id": "C0017658",
"name": "glomerulonephritis",
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} | {
"id": "C0017661",
"name": "berger 's disease",
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130
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} |
twelve cases of intracranial aneurysms occurring in infancy , childhood , and adolescence are presented and discussed . | nichd_parent_of | {
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} | {
"id": "C0001578",
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} |
the tc-pyp scan is valuable in the detection of peri-operative infarction following coronary artery surgery , and in patients with unstable angina the technique may detect small amounts of myocardial necrosis undetectable by more conventional means . | nichd_parent_of | {
"id": "C0021308",
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} | {
"id": "C0027051",
"name": "myocardial",
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199
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} |
some prognostic value can be expected in gn with the nephrotic syndrome ( ns ) : patients with steroid-sensitive ns excrete no fdp and patients with steroid-resistant ns excrete larger quantities of fdp . | nichd_parent_of | {
"id": "C0027726",
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} | {
"id": "C0403396",
"name": "steroid-sensitive ns",
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115
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} |
mention is also made of the fact that these disease may be transmitted to animals which allows an infectious genesis to be assumed . | nichd_parent_of | {
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} | {
"id": "C0009450",
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the different routes of spread of these tumors , as well as a review of the incidence of bone metastases in gynecological malignancies are discussed . | nichd_parent_of | {
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} | {
"id": "C0006826",
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it was noted that : -- patients without urologic disturbances had values under 1.5 micrograms in 12 hours in 93.4 % of the cases ; -- in 44 % of patients with non-malignant urological diseases ( urinary lithiasis ) the antigen values ranged between 1.5 and 3.0 micrograms in 12 hours ; -- patients with urothelial tumors had high values of the urinary carcinoembrionary antigen , in the range between 1.92 and 162.5 micrograms ; -- concentration of the urinary carcino-embionary antigen increases with the stage of the disease , with tumor polyploidia and in tumors with a high degree of anaplasia ; -- 10 -- 14 days after the removal of the tumor the values of the carcino-embrionary antigen show a significant decrease , even after total cystectomy but with cutaneous uretherostomy . | nichd_parent_of | {
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192
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} | {
"id": "C0451641",
"name": "urinary lithiasis",
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195,
212
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} |
as only females with raynaud phenomena showed digital artery closure , the diagnostic value of a combined finger and body cooling test in primary raynaud phenomena is high . | nichd_parent_of | {
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} | {
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} |
cape town had no proper facilities for dealing with infectious disease when , in 1894 , dr barney fuller , city moh , began a 6-year flight to establish the city hospital for infectious diseases . | nichd_parent_of | {
"id": "C0009450",
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} | {
"id": "C0205721",
"name": "hospital",
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} |
the exceptionally high rate of prevalence of intestinal protozoal infection in this population suggests that enteric protozoal infections are important among sexually transmitted diseases . | nichd_parent_of | {
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"name": "infection",
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} | {
"id": "C0036916",
"name": "sexually transmitted diseases",
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} |
numerous epidemiologic studies performed in the people 's republic of poland during the years 1966-1975 make evident that the morbidity of periodontal diseases in children and adolescents , 7-18 years of age , varies from 5.5 to 66.6 % . | nichd_parent_of | {
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57
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} | {
"id": "C0008059",
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171
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} |
in a series of 57 endarterectomies in 50 patients , 24 patients experienced postoperative headaches encompassing the entire spectrum of vascular headaches : nonspecific diffuse headaches , severe hemicranias , cluster headaches occurring early and delayed , chronic paroxysmal hemicranias , carotidynia , and eagle 's syndrome . | nichd_parent_of | {
"id": "C0018681",
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} | {
"id": "C0009088",
"name": "cluster headaches",
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it thus appears that the incidence of positive cea by immunoperoxidase staining of formalin-fixed , paraffin-embedded tumour tissue sections is much less than the frequency of blood or urinary cea elevations in patients with urothelial cancer . | nichd_parent_of | {
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} | {
"id": "C0006826",
"name": "cancer",
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} |
the echocardiographic features are a function of the size and shape of the myxoma , as well as the length and site of implantation of its pedicle . | nichd_parent_of | {
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} | {
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the authors report two new cases of cardiac disease associated with distomatosis : one case of biventricular fibroblastic parietal endocarditis affecting mainly the left side in a young female of 26 years , and one case of cardiomyopathy with atrial endocardial fibrosis , affecting especially the left ventricle in a man of 47 . | nichd_parent_of | {
"id": "C0018799",
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36,
51
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} | {
"id": "C0014118",
"name": "endocarditis",
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131,
143
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} |
the authors report two new cases of cardiac disease associated with distomatosis : one case of biventricular fibroblastic parietal endocarditis affecting mainly the left side in a young female of 26 years , and one case of cardiomyopathy with atrial endocardial fibrosis , affecting especially the left ventricle in a man of 47 . | nichd_parent_of | {
"id": "C0018799",
"name": "cardiac disease",
"pos": [
36,
51
]
} | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
223,
237
]
} |
bearing in mind the five cases reported in the literature , the authors propose a classification of cardiac disorders supposed to be due to distomatosis using three groups ( endocardial fibrosis , cardiomyopathy , myocarditis ) and relate them to a common pathogenesis based on immuno-allergic theory . | nichd_parent_of | {
"id": "C0018799",
"name": "of cardiac disorders",
"pos": [
97,
117
]
} | {
"id": "C0878544",
"name": "cardiomyopathy",
"pos": [
197,
211
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} |
bearing in mind the five cases reported in the literature , the authors propose a classification of cardiac disorders supposed to be due to distomatosis using three groups ( endocardial fibrosis , cardiomyopathy , myocarditis ) and relate them to a common pathogenesis based on immuno-allergic theory . | nichd_parent_of | {
"id": "C0018799",
"name": "of cardiac disorders",
"pos": [
97,
117
]
} | {
"id": "C0027059",
"name": "myocarditis",
"pos": [
214,
225
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} |
the disease has not been reported before in australia but has distinct similarities to an infectious leucoencephalomyelitis of young goats which has been described in north america . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
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11
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} | {
"id": "C0009450",
"name": "infectious",
"pos": [
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} |
between 1965-1972 244 individual mothers were admitted on 283 occasions accompanied by 287 children to a general hospital unit . | nichd_parent_of | {
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"name": "individual",
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22,
32
]
} | {
"id": "C0008059",
"name": "children",
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} |
hence the antigen ( s ) of tumour extracts that react with patient 's leucocytes are , at least partially , unrelated to cancer . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
27,
33
]
} | {
"id": "C0006826",
"name": "cancer",
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121,
127
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} |
there may be accompanying nonspecific immunologic abnormalities , which may denote that fibrosing alveolitis is part of the wide spectrum of diseases known as connective tissue disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
141,
149
]
} | {
"id": "C0009782",
"name": "connective tissue disorders",
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159,
186
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} |
from our trials in parastic diseases ( amoebiasis , schistosomiasis , fasciolasis , filariasis , hydatidosis , trichinosis ) and mycosis ( aspergillosis , candidiasis ) , it seems that the immuno-enzymatic labelling of the `` '' active '' '' precipitating reactions should only be taken in consideration . | nichd_parent_of | {
"id": "C0026946",
"name": "mycosis",
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129,
136
]
} | {
"id": "C0006840",
"name": "candidiasis",
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155,
166
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} |
fracture repair took longer in the latter group than in normal littermates presumably because tibial fracture occurred before the 2 week interval required for skeletal transformation from osteopetrotic to normal phenotype following transplantation of normal spleen cells . | nichd_parent_of | {
"id": "C0016658",
"name": "fracture",
"pos": [
0,
8
]
} | {
"id": "C0040185",
"name": "tibial fracture",
"pos": [
94,
109
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} |
this finding is not characteristic of this condition and clinico-pathologic correlation is needed for a definitive diagnosis . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
5,
12
]
} | {
"id": "C0011900",
"name": "diagnosis",
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124
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} |
the paper describes the use of 14 south african wild rodent species as experimental models and demonstrates the proven value of many of these as laboratory animals in research on bacterial infections ( plague , relapsing fever ) , rickettsial infections ( tickbite fever , louse typhus ) , viral infections ( poliomyelitis . rift-valley fever and other arbovirus infections , lassa fever ) , fungal infections ( histoplasmosis ) , parasitic infections ( schistosomiasis ) and in diabetes mellitus and cancer research . | nichd_parent_of | {
"id": "C0747256",
"name": "parasitic infections",
"pos": [
431,
451
]
} | {
"id": "C0036323",
"name": "schistosomiasis",
"pos": [
454,
469
]
} |
a sicilian family is described in which the alpha-thalassaemia gene is interacting in several members with beta-thalassaemia resulting in a balanced alpha/beta chain production ratio . | nichd_parent_of | {
"id": "C0039730",
"name": "thalassaemia",
"pos": [
50,
62
]
} | {
"id": "C0005283",
"name": "beta-thalassaemia",
"pos": [
107,
124
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} |
these coded records were then sampled according to various schedules and procedures and the fidelity with which each sampling schedule and procedure represented the content of the entire treatment record was evaluated . | nichd_parent_of | {
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"name": "procedure",
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82
]
} | {
"id": "C0220825",
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217
]
} |
the authors consider this disease not as a carcinoma and are not sure whether it is a true tumor at all . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
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26,
33
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
91,
96
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} |
the blood culturing technique , based upon centrifugation , has shown a ten-fold increase in isolation of fungi from blood and has provided for : quantitation or organisms , unlimited selection of media and atmospheres for primary culturing , and a 1:200 dilution of microorganisms away from serum antimicrobial factors and antibiotics . | nichd_parent_of | {
"id": "C0029235",
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} | {
"id": "C0445623",
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267,
281
]
} |
using these values as normal , csf from patients with syphilis , encephalitis , subacute sclerosing panencephalitis ( sspe ) , and multiple sclerosis ( ms ) was studied . | nichd_parent_of | {
"id": "C0014038",
"name": "encephalitis",
"pos": [
65,
77
]
} | {
"id": "C0038522",
"name": "subacute sclerosing panencephalitis",
"pos": [
80,
115
]
} |
there was arthralgia in 7 cases , vertebral pain in 7 cases and myalgia in 3 cases . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
44,
48
]
} | {
"id": "C0231528",
"name": "myalgia",
"pos": [
64,
71
]
} |
tumoral lesions were detected in 105 patients , with a total of 125 adenomas and 31 cancers ; | nichd_parent_of | {
"id": "C0027651",
"name": "tumoral",
"pos": [
0,
7
]
} | {
"id": "C0006826",
"name": "cancers",
"pos": [
84,
91
]
} |
platelet antibody determination by the pf3 test was carried out in 96 thrombocytopenic patients with various disorders , 31 repeatedly transfused patients with or without thrombocytopenia and 24 patients with autoimmune disease ( sle and myasthenia gravis ) without thrombocytopenia . | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune",
"pos": [
209,
219
]
} | {
"id": "C0026896",
"name": "myasthenia gravis",
"pos": [
238,
255
]
} |
various suggestions were made for resolving these difficulties through such means as equating samples for level of deterioration , utilizing modern , objective diagnostic techniques in the selection of samples , comparing subtypes of brain damage and schizophrenia , and using test procedures that have been shown to assess dispositional characteristics of the conditions under study , rather than their epiphenomena . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic techniques",
"pos": [
160,
181
]
} | {
"id": "C0022885",
"name": "test",
"pos": [
277,
281
]
} |
it is concluded that the individual normoglicemia is essential for the control of the diabetic woman , and that mother 's glicemia will have an effect on the fetus , producing a reduction of the gradient of mother-fetus glicemia and , on account of this , also a reduction of the hiperinsulinism reaction of the fetus with all its ill results . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
25,
35
]
} | {
"id": "C0015965",
"name": "fetus",
"pos": [
312,
317
]
} |
in comparison with ( mostly normal ) iges levels , the igea.h . concentration appears relatively elevated , not only with uveitis patients , but also with cataract patients , above all when lenticular opacity is accompanied by other ophthalmic diseases ( glaucoma , high myopia , diabetes ) . | nichd_parent_of | {
"id": "C0015397",
"name": "ophthalmic diseases",
"pos": [
233,
252
]
} | {
"id": "C0017601",
"name": "glaucoma",
"pos": [
255,
263
]
} |
three techniques are discussed : resection and reposition , considered to be procedures involving the septum only , and rhinoplasty where the operation involves the whole of the pyramid . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
"pos": [
77,
87
]
} | {
"id": "C0543467",
"name": "operation",
"pos": [
142,
151
]
} |
the globulin concentrations in colostrum were not influenced by the breed , the season , the number of calvings , the length of the dry period and the level of feeding during this period but the time of the first feeding or milking proved to be of prime importance . | nichd_parent_of | {
"id": "C0040223",
"name": "time",
"pos": [
195,
199
]
} | {
"id": "C2911686",
"name": "first feeding",
"pos": [
207,
220
]
} |
the babies fed on formula plus citrate did not make greater gains in weight , length , head circumference , skinfold thickness , or midarm muscle circumference , although they had a greater blood base excess . | nichd_parent_of | {
"id": "C1444754",
"name": "length",
"pos": [
78,
84
]
} | {
"id": "C0262499",
"name": "head circumference",
"pos": [
87,
105
]
} |
132 patients with pure mono-valvular cardiopathies ( mitral incompetence , aortic stenosis and aortic incompetence ) were classified into two groups according to the values of the systolic work index/myocardial mass ratio ( swi/mlv ) . | nichd_parent_of | {
"id": "C0018824",
"name": "valvular cardiopathies",
"pos": [
28,
50
]
} | {
"id": "C0026266",
"name": "mitral incompetence",
"pos": [
53,
72
]
} |
132 patients with pure mono-valvular cardiopathies ( mitral incompetence , aortic stenosis and aortic incompetence ) were classified into two groups according to the values of the systolic work index/myocardial mass ratio ( swi/mlv ) . | nichd_parent_of | {
"id": "C0018824",
"name": "valvular cardiopathies",
"pos": [
28,
50
]
} | {
"id": "C0003507",
"name": "aortic",
"pos": [
95,
101
]
} |
it may be that hodgkin 's disease is no nosological entity but clinical and morphological manifestation of two diseases , namely infectious granuloma in youth and true neoplasm in the elderly . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
111,
119
]
} | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
168,
176
]
} |
effect of propranolol on enzymatic and histochemical estimates of infarct size in experimental myocardial infarction . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
66,
73
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
95,
116
]
} |
it is suggested that the anti-arrhythmia effect of non-depolarizing muscle relaxants may prevent ventricular arrhythmia in patients receiving halothane . | nichd_parent_of | {
"id": "C0003811",
"name": "arrhythmia",
"pos": [
30,
40
]
} | {
"id": "C0085612",
"name": "ventricular arrhythmia",
"pos": [
97,
119
]
} |
electron microscopy of liver and spleen showed phagocytosis of f. tularensis organisms by macrophages and polymorphonuclear leucocytes , but many bacteria survived phagocytosis and were released on destruction of the cells . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
77,
86
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
146,
154
]
} |
effects of a selective inhibitor of type a monoamine oxidase -- lilly 51641 -- on behavior , sleep and circadian rhythms in depressed and schizophrenic patients . | nichd_parent_of | {
"id": "C0004927",
"name": "behavior",
"pos": [
82,
90
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
93,
98
]
} |
a quantitative study of the individual steps in the isolation of elastin from mature and fetal aortas of rabbits was carried out . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
28,
38
]
} | {
"id": "C0015965",
"name": "fetal",
"pos": [
89,
94
]
} |
3 ) assuring that where necessary , an outreach person is meeting the needs of the family and child on an intensive , sustained , caring and creative basis . | nichd_parent_of | {
"id": "C0027361",
"name": "person",
"pos": [
48,
54
]
} | {
"id": "C0008059",
"name": "child",
"pos": [
94,
99
]
} |
the prevalence of the other groups of diseases were : the psychiatric diseases 2.2 % , the urological diseases 1.4 % and the hematological diseases 0.8 % . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
38,
46
]
} | {
"id": "C0042075",
"name": "urological diseases",
"pos": [
91,
110
]
} |
the prevalence of the other groups of diseases were : the psychiatric diseases 2.2 % , the urological diseases 1.4 % and the hematological diseases 0.8 % . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
38,
46
]
} | {
"id": "C0018939",
"name": "hematological diseases",
"pos": [
125,
147
]
} |
in spite of their difficulty these methods of investigation can allow couples at risk to have normal children or heterozygous infants . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
101,
109
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
126,
133
]
} |
the organism is considered to belong to a new species of the genus mycobacterium and has been deposited in the american type culture collection , rockville , maryland , usa ( atcc 29356 ) and in the czechoslovak collection of microorganisms , czechoslovak national collection of type cultures , institute of hygiene and epidemiology , srobarova 48 , 100 42 prague 10 under the my 220/77 . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
4,
12
]
} | {
"id": "C0445623",
"name": "microorganisms",
"pos": [
226,
240
]
} |
the heritable disorder of connective tissue , now termed ehlers -- danlos syndrome , was described by chernogubov , a russian dermatologist , in 1892 . | nichd_parent_of | {
"id": "C0410787",
"name": "heritable disorder of connective tissue",
"pos": [
4,
43
]
} | {
"id": "C0013720",
"name": "ehlers",
"pos": [
57,
63
]
} |
the transformation-reformation potential of the ascomycete in vivo , the non-recognizable status of the conidial bodies , and the inability to recapture the adult autonomous form by conventional laboratory means , despite their known presence , suggests a possible relationship of this micro-organism to certain of the acute , chronic inflammatory diseases , pleomorphic tumors , granulomas , and the malignancies . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
371,
377
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
401,
413
]
} |
based upon the hypothesis that a factor most pertinent to the absence of an effective immune response in cancer is the inadequacy of the antigenic stimulus provided by the neoplasm , either in terms of weak immunogenicity of the tumor antigen or of the necessary antigen mass available to the reticuloendothelial tissues at any one time for effective sensitization , the host immune response capabilities were stimulated within a time frame synchronous with a greater release of tumor antigens . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasm",
"pos": [
172,
180
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
271,
275
]
} |
the relatively most frequent cancers were : males : skin 30 % , malignant lymphomas 13 % , primary liver cancer 11 % . | nichd_parent_of | {
"id": "C0006826",
"name": "cancers",
"pos": [
29,
36
]
} | {
"id": "C0024299",
"name": "malignant lymphomas",
"pos": [
64,
83
]
} |
the relatively most frequent cancers were : males : skin 30 % , malignant lymphomas 13 % , primary liver cancer 11 % . | nichd_parent_of | {
"id": "C0006826",
"name": "cancers",
"pos": [
29,
36
]
} | {
"id": "C0024620",
"name": "primary liver cancer",
"pos": [
91,
111
]
} |
the three patient developed a syndrome with dysesthesia and hypoesthesia after several weeks or months , and this remained fairly constant . | nichd_parent_of | {
"id": "C0392699",
"name": "dysesthesia",
"pos": [
44,
55
]
} | {
"id": "C0020580",
"name": "hypoesthesia",
"pos": [
60,
72
]
} |
these studies provide a basis for the development of serological markers of malignancy in csmc . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
76,
86
]
} | {
"id": "C0678222",
"name": "csmc",
"pos": [
90,
94
]
} |
nutritional disorders , especially hypovitaminosis a and osteodystrophies , were common ( 19.7 per cent ) , particularly in pets . | nichd_parent_of | {
"id": "C3714509",
"name": "nutritional disorders",
"pos": [
0,
21
]
} | {
"id": "C1510471",
"name": "hypovitaminosis",
"pos": [
35,
50
]
} |
the presence of complement fixing antibodies to four viruses with oncogenic potential for animals was studied in children ( including neonates and infants ) . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
113,
121
]
} | {
"id": "C0021289",
"name": "neonates",
"pos": [
134,
142
]
} |
the presence of complement fixing antibodies to four viruses with oncogenic potential for animals was studied in children ( including neonates and infants ) . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
113,
121
]
} | {
"id": "C0021270",
"name": "infants",
"pos": [
147,
154
]
} |
while other vaccinia strains , such as the elstree virus , experience a drastic increase of virulence in the immunosuppressed organism ( subjected to whole-body irradiation ) , the mva virus can not be activated not even in this situation . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
126,
134
]
} | {
"id": "C0042776",
"name": "virus",
"pos": [
185,
190
]
} |
this new-method implies a simple procedure , without serious complications that will facilitate the development of clinical studies and further investigation of the parotid gland . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
33,
42
]
} | {
"id": "C0220825",
"name": "investigation",
"pos": [
144,
157
]
} |
fine structural studies on the septa of candida albicans in vitro ( when leading a saprophytic existence ) and the organism in its invasive form ( as a pathogen in oral candidosis ) have shown that in the former the septum exhibits a unique central perforation resembling an aggregate of fine canaliculi connecting one cell to the other . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
"pos": [
115,
123
]
} | {
"id": "C0450254",
"name": "pathogen",
"pos": [
152,
160
]
} |
procedure for processing of central nervous system tissue for immunofluorescence , light , and electron microscopic evaluation . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
0,
9
]
} | {
"id": "C0220825",
"name": "evaluation",
"pos": [
116,
126
]
} |
physical signs were more helpful in diagnosis and it is considered that the presence of an effusion , quadriceps wasting , and patello-femoral crepitus are the most important clinical findings in the diagnosis of chondromalacia patellae . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
175,
192
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
200,
209
]
} |
in the search for new methods of diagnosing or suspension of intrauterine infection , bacteriologic methods were used , sections of the placenta were examined , content of igg , iga and igm immunoglobulins was determined , and neutrophilic leukocytes in peripheral blood were counted in the parturient women and their children , and in neonates polymorphonuclear leukocytes were also counted in gastric smears . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
318,
326
]
} | {
"id": "C0021289",
"name": "neonates",
"pos": [
336,
344
]
} |
there are given some data concerning the substances present in industrial oils , hardeners and epoxy resin solvents , drugs sensitizing nurses , several new sources of chromium allergens , essential oils and synthetic flavours . | nichd_parent_of | {
"id": "C0439861",
"name": "substances",
"pos": [
41,
51
]
} | {
"id": "C0002092",
"name": "allergens",
"pos": [
177,
186
]
} |
a variety of tests were performed to determine the immune status of a group of patients with scleroderma ( progressive systemic sclerosis ) . | nichd_parent_of | {
"id": "C0011644",
"name": "scleroderma",
"pos": [
93,
104
]
} | {
"id": "C0036421",
"name": "progressive systemic sclerosis",
"pos": [
107,
137
]
} |
the current diagnostic criteria are pain compatible with biliary pain in the absence of gallstones and other organic gastrointestinal disease , or other disorders which might produce abdominal pain , together with reproduction of the patient 's symptoms by cholecystokinin , or morphine , or both . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
36,
40
]
} | {
"id": "C0000737",
"name": "abdominal pain",
"pos": [
183,
197
]
} |
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