text stringlengths 57 1.72k | relation stringclasses 125
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|---|---|---|---|
we describe ways of raising human hybridomas that produce rf antibodies in rheumatoid arthritis ( ra ) in order to elucidate how these antibodies differ from the rf antibodies that are part of the normal immune response in man and animals , and from those in diseases other than ra , e.g . in m-components seen in mixed cryoglobulinaemia and in waldenstrom 's macroglobulinaemia . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
86,
95
]
} | {
"id": "C0003873",
"name": "ra",
"pos": [
279,
281
]
} |
if the clinical findings are ambiguous , too , differentiation may become difficult , and the only diagnosis is `` '' chronic unspecific synovitis '' '' . | nichd_parent_of | {
"id": "C0037088",
"name": "clinical findings",
"pos": [
7,
24
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
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]
} |
the behavioral excitation to l-dopa in 6-ohda-treated rats consisted of increases in sniffing and increases in locomotion and/or rearing , along with decreases in resting and sleep . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
4,
14
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
175,
180
]
} |
clinical and laboratory findings included an erythematous malar flush , proteinuria , casts in the urine and a positive antinuclear factor . | nichd_parent_of | {
"id": "C0587081",
"name": "laboratory findings",
"pos": [
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32
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} | {
"id": "C0033687",
"name": "proteinuria",
"pos": [
72,
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} |
the finding of foam cells prompted a review of other renal biopsies which were diagnosed as mpgn type i and diffuse proliferative lupus nephritis ( dpln ) , including lupus-associated mpgn . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
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11
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} | {
"id": "C0011900",
"name": "diagnosed",
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} |
this procedure provides a means to isolate cell populations treated in g2 , for the investigation of g2 arrest . | nichd_parent_of | {
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"name": "procedure",
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} | {
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gene complementation test became possible among families of a hereditary disease by this technique which was the daybreak of the genetic analyses of human hereditary diseases in laboratories . | nichd_parent_of | {
"id": "C0022885",
"name": "test",
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25
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} | {
"id": "C0679560",
"name": "genetic",
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129,
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} |
we therefore compared the effects of these metabolites to those of propafenone on action potential characteristics of canine purkinje fibers at a wide range of cycle lengths . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
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114
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} | {
"id": "C1444754",
"name": "lengths",
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behavioral control of abnormal breathing in sleep was studied to determine if an intervention procedure could reduce apnea duration and also sao2 ( blood oxygen ) desaturation levels . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
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} | {
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"name": "sleep",
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these results demonstrate that da neurone function is important in the formation of gastric ulcers in tumour-bearing animals and suggest that such compounds may be useful in cancer management . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
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} | {
"id": "C0006826",
"name": "cancer",
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174,
180
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} |
the incidence of anti-igg antibodies ( rheumatoid factors , rf ) in body fluids ( sera , synovial fluids and aqueous humor ) selected from 62 normal and 275 diseased dogs was studied . | nichd_parent_of | {
"id": "C0003241",
"name": "antibodies",
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26,
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} | {
"id": "C0035448",
"name": "rf",
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in group 2 , the recipients developed clinical signs of graft-versus-host disease ( gvhd ) after 1 week , and at the end of the 2nd week the animals showed signs of severe illness , leading to death due to gvhd . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
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} | {
"id": "C0011065",
"name": "death",
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} |
the most common psychiatric syndromes that resulted from these neuropathologic disorders were dementia syndrome ( 72 % ) , organic personality syndrome ( 14 % ) , and organic psychotic disorders ( 12 % ) . | nichd_parent_of | {
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"name": "disorders",
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} | {
"id": "C0039082",
"name": "syndrome",
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143,
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} |
since the clinical signs that characterize nph -- incontinence , difficulty walking , and dementia -- occur frequently in the elderly in association with a wide variety of disorders , attention is paid to the differential diagnosis of nph on the basis of both clinical findings and laboratory tests . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
10,
24
]
} | {
"id": "C0311394",
"name": "difficulty walking",
"pos": [
65,
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} |
medical disorders were common , and older depressed patients showed a clear excess of cardiovascular disorders . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
8,
17
]
} | {
"id": "C0007222",
"name": "cardiovascular disorders",
"pos": [
86,
110
]
} |
the data suggest that ophthalmological disorders may trigger idiopathic blepharospasm in a substantial proportion of cases predisposed to develop this condition . | nichd_parent_of | {
"id": "C0015397",
"name": "ophthalmological disorders",
"pos": [
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} | {
"id": "C0005747",
"name": "blepharospasm",
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72,
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} |
thus , the interaction of b. pertussis with neutrophils appears to be complex , reflecting both the alteration of leucocyte function by secreted virulence components of the organism and , in the absence of opsonins , the surface properties of the bacterium . | nichd_parent_of | {
"id": "C0029235",
"name": "organism",
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181
]
} | {
"id": "C0004611",
"name": "bacterium",
"pos": [
247,
256
]
} |
analysis of the ganglioside patterns of 53 tumors indicated that patients who were either disease positive 2 yr following surgery or dead of disease , had significantly ( p less than 0.005 ) less gt1b plus gd1b than tumors from patients that were disease free 2 yr post surgery . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
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} | {
"id": "C0027651",
"name": "tumors",
"pos": [
216,
222
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} |
a major finding is that motion is only perceived when the time interval between successive frames falls below about 500 ms , and the duration of each frame exceeds about 80 ms . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
8,
15
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} | {
"id": "C0085639",
"name": "falls",
"pos": [
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} |
it is assuming a pivotal role in the treatment of gram-positive infections of central nervous system or dialysis shunts , endocarditis , meningitis , and septicemia . | nichd_parent_of | {
"id": "C0007684",
"name": "of",
"pos": [
47,
49
]
} | {
"id": "C0025289",
"name": "meningitis",
"pos": [
137,
147
]
} |
the case of the heat-shock response in organisms ranging from man to bacteria is discussed . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
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]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
69,
77
]
} |
only the late eluting fraction from type 2 fluids had approximately equal immunoreactivity with both antibodies . | nichd_parent_of | {
"id": "C0005889",
"name": "fluids",
"pos": [
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49
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
101,
111
]
} |
in addition to authentic dhea-s , breast cyst fluids contain other materials that react with dhea-s antibodies . | nichd_parent_of | {
"id": "C0005889",
"name": "fluids",
"pos": [
46,
52
]
} | {
"id": "C0003241",
"name": "antibodies",
"pos": [
100,
110
]
} |
the results of the present study indicate that the 'ss susceptibility gene ' in greek patients is linked with the hla-dr5 expression gene and they support the hypothesis that the fundamental pss gene may belong to another locus . | nichd_parent_of | {
"id": "C1527336",
"name": "ss",
"pos": [
52,
54
]
} | {
"id": "C0151449",
"name": "pss",
"pos": [
191,
194
]
} |
a screening of bulimia , an eating disorder associated to obesity and anorexia nervosa , has been carried out in the city of buenos aires . | nichd_parent_of | {
"id": "C0013473",
"name": "eating disorder",
"pos": [
28,
43
]
} | {
"id": "C0003125",
"name": "anorexia",
"pos": [
70,
78
]
} |
in order to clarify the corticotrophic capacity of the fetal sheep anterior pituitary in late gestation , we have measured the relative levels of messenger rna for the acth precursor molecule pro-opiomelanocortin ( pomc ) in individual fetal sheep anterior pituitaries collected between 100 and 144 days of gestation . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
225,
235
]
} | {
"id": "C0015965",
"name": "fetal",
"pos": [
236,
241
]
} |
increased levels of endogenous growth hormone ( gh ) during childhood and adolescence result in a significant elevation of final height both in humans and in laboratory animals . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
60,
69
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
74,
85
]
} |
patients with common hand warts and simple plantar warts attending a general practice wart clinic in northern ireland were assigned to one of three treatment groups - liquid nitrogen applied weekly , daily application of wart paint ( lactic acid one part , salicylic acid one part , collodion four parts ) , or a combination of the two . | nichd_parent_of | {
"id": "C0043037",
"name": "common",
"pos": [
14,
20
]
} | {
"id": "C0042548",
"name": "plantar warts",
"pos": [
43,
56
]
} |
to investigate the toxic potential of rapid intravenous quinine administration in severe malaria , the pharmacokinetic properties of low-dose quinine dihydrochloride injection ( 4 mg/kg body weight , equivalent to 3.3 mg base/kg ) followed one hour later by infusion of 16 mg/kg over 3 h were studied in 7 patients with cerebral malaria . | nichd_parent_of | {
"id": "C0024530",
"name": "malaria",
"pos": [
89,
96
]
} | {
"id": "C0024534",
"name": "cerebral malaria",
"pos": [
320,
336
]
} |
clinically , the intraocular inflammation was most frequently an asymptomatic , chronic , non-granulomatous , iridocyclitis which was bilateral in 71 % of cases . | nichd_parent_of | {
"id": "C0042164",
"name": "intraocular inflammation",
"pos": [
17,
41
]
} | {
"id": "C1510449",
"name": "chronic",
"pos": [
80,
87
]
} |
25 of 42 patients with s. mansoni infections had detectable circulating antigen while sera from all of 45 normal subjects and patients with other parasitic infections did not react . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
34,
44
]
} | {
"id": "C0747256",
"name": "parasitic infections",
"pos": [
146,
166
]
} |
the harmful effects of the disease may be masked in these more active and gregarious children , particularly when infections are mild and other parasitic infections and nutrional deficiencies are common . | nichd_parent_of | {
"id": "C3714514",
"name": "infections",
"pos": [
114,
124
]
} | {
"id": "C0747256",
"name": "parasitic infections",
"pos": [
144,
164
]
} |
human immunodeficiency virus ( hiv ) is a cytoplasmic retrovirus which is transmitted via body fluids , especially through blood products and sexual contact , and is the causative agent of the acquired immunodeficiency syndrome ( aids ) . | nichd_parent_of | {
"id": "C0005889",
"name": "body fluids",
"pos": [
90,
101
]
} | {
"id": "C0456388",
"name": "blood products",
"pos": [
123,
137
]
} |
protozoal diseases were constituted of 15 cases of amebiasis , 7 cases of leishmaniasis ( imported ) and 5 cases of pneumocystis carinii infections . | nichd_parent_of | {
"id": "C0033740",
"name": "protozoal diseases",
"pos": [
0,
18
]
} | {
"id": "C0023281",
"name": "leishmaniasis",
"pos": [
74,
87
]
} |
the objective is to evaluate the relative importance of physical after-effects , socio-economic characteristics , social and environmental factors on the degree of social integration subsequently achieved . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
20,
28
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
56,
64
]
} |
left ventricular ejection fraction , regional wall motion , hospital mortality rate , and reocclusion rate of the infarct-related coronary artery after thrombolytic therapy were examined in 164 consecutive patients who were admitted within 12 hours of the onsets of their symptoms of acute myocardial infarction . | nichd_parent_of | {
"id": "C0021308",
"name": "infarct",
"pos": [
114,
121
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
290,
311
]
} |
older agents , alone or in combination , possess equivalent or greater activity against gram-positive and anaerobic organisms and most community-acquired gram-negative enteric pathogens . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
116,
125
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
176,
185
]
} |
we evaluated the effects of an 8-week progressive muscle-relaxation therapy regimen on the headache activity of 10 elderly tension-headache subjects . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
91,
99
]
} | {
"id": "C0033893",
"name": "headache",
"pos": [
131,
139
]
} |
however , a polysomnogram conducted on this subject at the end of the study revealed a fragmented sleep pattern secondary to periodic movements of sleep ( nocturnal myoclonus ) . | nichd_parent_of | {
"id": "C0004927",
"name": "conducted",
"pos": [
26,
35
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
147,
152
]
} |
these encouraging but preliminary results call for further controlled evaluations of the efficacy of this behavioral treatment package for sleep-maintenance insomnia . | nichd_parent_of | {
"id": "C0004927",
"name": "behavioral",
"pos": [
106,
116
]
} | {
"id": "C0037313",
"name": "sleep",
"pos": [
139,
144
]
} |
the studied material included cases with pituitary adenoma characterized by excessive secretion of growth hormone ( somatotropinoma ) , prolactin ( prolactinoma ) or alpha subunits of glycoprotein hormones ( alphoma ) , and those with hormonally inactive adenoma . | nichd_parent_of | {
"id": "C0032000",
"name": "pituitary adenoma",
"pos": [
41,
58
]
} | {
"id": "C0033375",
"name": "prolactinoma",
"pos": [
148,
160
]
} |
such features as high incidence of thyroid enlargement of low degree ( ob and i ) , higher incidence of goiter in women than in men , absence of cases with hypothyroidism , and low incidence of nodular goiter , characterize the observed endemia++ as mild . | nichd_parent_of | {
"id": "C0018021",
"name": "goiter",
"pos": [
104,
110
]
} | {
"id": "C0018023",
"name": "nodular goiter",
"pos": [
194,
208
]
} |
similarly , implanted biomaterials tend to potentiate bacteria on their surfaces so that normally friendly special or opportunistic organisms become virulent pathogens . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
132,
141
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
158,
167
]
} |
we have noticed that eeg records with no or small changes we met in patients whose clinical symptoms disappeared during 10 days from the beginning of the disease , where with the neurological syndrome lasting for a longer period , the number of the records with more severe changes was considerably larger . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
154,
161
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
192,
200
]
} |
the results of this treatment were evaluated immediately after the treatment and one and two years later , using a numerical scale of neurological examination in the scales of motor efficiency a . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluated",
"pos": [
35,
44
]
} | {
"id": "C0027853",
"name": "neurological examination",
"pos": [
134,
158
]
} |
the problems related to the distribution in the territory of live and modified antirabies vaccines , the immunological value of inactivated vaccines , the connections between sylvatic rabies and bat rabies ( or pseudorabies ) , are discussed . | nichd_parent_of | {
"id": "C0042210",
"name": "vaccines",
"pos": [
90,
98
]
} | {
"id": "C0042212",
"name": "inactivated vaccines",
"pos": [
128,
148
]
} |
in order to examine the effect of sleep position on sleep apnea episodes , seven male patients diagnosed as having obstructive sleep apnea syndrome without any organic complication of the upper airway were studied while lying in a supine or lateral position during an all-night polysomnographic study . | nichd_parent_of | {
"id": "C0037315",
"name": "sleep apnea",
"pos": [
52,
63
]
} | {
"id": "C0520679",
"name": "obstructive sleep apnea syndrome",
"pos": [
115,
147
]
} |
reports that immunizations with leukemia-derived hybrid cells prolonged the survival of leukemic mice led us to attempt an analogous approach in two adult patients with acute myeloid leukemia ( aml ) . | nichd_parent_of | {
"id": "C0023418",
"name": "derived",
"pos": [
41,
48
]
} | {
"id": "C0023467",
"name": "acute myeloid leukemia",
"pos": [
169,
191
]
} |
report is given on thymectomies in childhood and adolescence which produce in general excellent results . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
35,
44
]
} | {
"id": "C0001578",
"name": "adolescence",
"pos": [
49,
60
]
} |
in addition to their importance in human disease , studies of these viruses are helping to provide new insights into the molecular mechanisms of gene regulation , fundamental aspects of the immune system , and of the origin , cellular and molecular pathogenesis of human tumors . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
41,
48
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
271,
277
]
} |
major causes of referral were cataract , glaucoma , fundus changes , headaches/migraine/eye pain and lowered visual acuity ; | nichd_parent_of | {
"id": "C0018681",
"name": "headaches",
"pos": [
69,
78
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
79,
87
]
} |
significant proteinuria developed in all but one patient and nephrotic-range proteinuria was noted in 21 per cent . | nichd_parent_of | {
"id": "C0033687",
"name": "proteinuria",
"pos": [
12,
23
]
} | {
"id": "C0445118",
"name": "nephrotic-range proteinuria",
"pos": [
61,
88
]
} |
in chronic feeding studies with rats , the incidence of tumors and malignant tumors in test groups was lower than that in the control . | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
56,
62
]
} | {
"id": "C0006826",
"name": "malignant tumors",
"pos": [
67,
83
]
} |
the presurgical symptoms were pain , headache , joint pain , mastoid pain , infection , food impaction and orthodontic need . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
30,
34
]
} | {
"id": "C0003862",
"name": "joint pain",
"pos": [
48,
58
]
} |
other conditions which are known to be associated with sudden death include : dilated or congestive cardiomyopathy , hypertrophic cardiomyopathy , mitral valve prolapse , valvular heart disease , wolff-parkinson-white syndrome , myocarditis , congenital heart disease , electrolyte abnormalities , long qt syndromes , proarrhythmic effects of drugs , and less common conditions such as myocardial tumors and pulmonary hypertension . | nichd_parent_of | {
"id": "C0152021",
"name": "congenital heart disease",
"pos": [
243,
267
]
} | {
"id": "C0023976",
"name": "long qt syndromes",
"pos": [
298,
315
]
} |
surprisingly , these high concentrations were not associated with a clear therapeutic effect in dermatoses ( e.g . psoriasis ) which are usually responsive to oral retinoids . | nichd_parent_of | {
"id": "C0037274",
"name": "dermatoses",
"pos": [
96,
106
]
} | {
"id": "C0033860",
"name": "psoriasis",
"pos": [
115,
124
]
} |
surgical therapy should be directed at complete removal of the tumor as recurrence has been reported if a less than complete resection has been performed . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical",
"pos": [
0,
8
]
} | {
"id": "C0015250",
"name": "complete",
"pos": [
116,
124
]
} |
in conclusion : in the order of importance , antecedent endocarditis , bioprostheses and aortic position are risk factors in the development of pve . | nichd_parent_of | {
"id": "C0014118",
"name": "endocarditis",
"pos": [
56,
68
]
} | {
"id": "C0340359",
"name": "pve",
"pos": [
144,
147
]
} |
congenital abnormalities presented include holoprosencephaly , hydranencephaly , agenesis of the corpus callosum with interhemispheric cyst , porencephaly , schizencephaly , and arachnoid cyst . | nichd_parent_of | {
"id": "C0010709",
"name": "cyst",
"pos": [
135,
139
]
} | {
"id": "C0078981",
"name": "arachnoid cyst",
"pos": [
178,
192
]
} |
tricuspid regurgitation was detected in 399 of 4670 children ( 8.5 % ) with congenital heart disease and in 26 of 106 newborns ( 25 % ) with respiratory distress . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
52,
60
]
} | {
"id": "C0021289",
"name": "newborns",
"pos": [
118,
126
]
} |
one of the patients had known congenital heart disease and heart surgery in the past , and the diagnosis of pda was missed both on catheterization and in the operating room . | nichd_parent_of | {
"id": "C0152021",
"name": "congenital heart disease",
"pos": [
30,
54
]
} | {
"id": "C0013274",
"name": "pda",
"pos": [
108,
111
]
} |
although weak associations between individual autoantibody parameters and the other immunogenetic markers were detected , there were no significant hla , c4 or gm association with either ana subsets or rf , a finding which agrees with , and also extends previous hla studies of predominantly seropositive ra cohorts . | nichd_parent_of | {
"id": "C0003241",
"name": "ana",
"pos": [
187,
190
]
} | {
"id": "C0035448",
"name": "rf",
"pos": [
202,
204
]
} |
the neurofibromatosis clinic of the children 's hospital of philadelphia is a multidisciplinary clinic that provides a setting in which the diagnosis of neurofibromatosis can be made and follow-up of children with neurofibromatosis coordinated . | nichd_parent_of | {
"id": "C0162678",
"name": "neurofibromatosis clinic",
"pos": [
4,
28
]
} | {
"id": "C0027831",
"name": "neurofibromatosis",
"pos": [
214,
231
]
} |
it therefore is assisting physicians in better understanding the full expression of these heritable disorders , such as the extent of optic pathway involvement in optic nerve glioma , the presence of hamartomas in ts , and abnormal myelination in sturge-weber syndrome . | nichd_parent_of | {
"id": "C0019247",
"name": "heritable disorders",
"pos": [
90,
109
]
} | {
"id": "C0038505",
"name": "sturge-weber syndrome",
"pos": [
247,
268
]
} |
however , the rossavik procedure can be used to generate individual growth curve standards for weight estimates , a characteristic not shared with other weight estimation procedures . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
116,
130
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
153,
159
]
} |
demonstration of hpv 16 dna in siha cells ( siha cells only contain 1-2 hpv genome copies ) was possible only by use of digoxigenin-labeled hpv 16 gene probes , as well as an improved purification of the sample dna from vector contaminations . | nichd_parent_of | {
"id": "C0021344",
"name": "hpv",
"pos": [
17,
20
]
} | {
"id": "C0999806",
"name": "hpv 16",
"pos": [
140,
146
]
} |
nevertheless , more research is needed to further clarify the complex relationships between hysteria , depression and pain , and to more exactly determine the relative importance of hysterical and depressive features in chronic pain patients . | nichd_parent_of | {
"id": "C0030193",
"name": "pain",
"pos": [
118,
122
]
} | {
"id": "C0150055",
"name": "chronic pain",
"pos": [
220,
232
]
} |
epoxides are intermediates in the metabolism of many alkenes and aromatic compounds in higher organisms and in microorganisms . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
94,
103
]
} | {
"id": "C0445623",
"name": "microorganisms",
"pos": [
111,
125
]
} |
the results indicate that hmpao brain spect is valuable for the detection of rcbf abnormalities in seizure patients and that patients with partial seizures have mostly several abnormally perfused areas in their brains . | nichd_parent_of | {
"id": "C0036572",
"name": "seizure",
"pos": [
99,
106
]
} | {
"id": "C0751495",
"name": "partial seizures",
"pos": [
139,
155
]
} |
one of them was in deep coma , with severe ventricular arrhythmias and had several episodes of ventricular fibrillation controlled with defibrillatory procedures . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
"pos": [
43,
66
]
} | {
"id": "C0042510",
"name": "ventricular fibrillation",
"pos": [
95,
119
]
} |
features of the immune deficiency include absence of plasma cells at mucosal sites , reduction in weight of thymus and spleen relative to body weight , and low serum levels of some immunoglobulin ( ig ) isotypes . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
0,
8
]
} | {
"id": "C0005910",
"name": "body weight",
"pos": [
138,
149
]
} |
moulds or fungi that grow in grains and seeds during storage and transport cause germination decrease , visible mouldiness , discoloration , musty or sour odours , caking , chemical and nutritional changes , reduction in processing quality , and form of mycotoxins . | nichd_parent_of | {
"id": "C0016832",
"name": "fungi",
"pos": [
10,
15
]
} | {
"id": "C0369241",
"name": "mouldiness",
"pos": [
112,
122
]
} |
whereas defined selenium deficiency diseases are well characterized in animals , analogous syndromes in humans are unknown or occur only rarely under conditions of extreme selenium depletion . | nichd_parent_of | {
"id": "C0012634",
"name": "diseases",
"pos": [
36,
44
]
} | {
"id": "C0039082",
"name": "syndromes",
"pos": [
91,
100
]
} |
the development of stroke in patients with sickle hemoglobinopathies and the possible role of platelets and antiplatelet therapy in cerebrovascular accidents in sickle-cell anemia are discussed . | nichd_parent_of | {
"id": "C0019045",
"name": "hemoglobinopathies",
"pos": [
50,
68
]
} | {
"id": "C0002895",
"name": "sickle-cell anemia",
"pos": [
161,
179
]
} |
to clarify the state of vitamin d production by the developing kidney , firstly , we measured serum levels of 1,25 ( oh ) 2d and 24,25 ( oh ) 2d in humans of different ages ( pregnant and nonpregnant women , adult males , children and newborn infants ) and secondly , we measured 1 alpha- and 24-hydroxylase activity in the kidney mitochondria of rats at different ages . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
"pos": [
222,
230
]
} | {
"id": "C0021289",
"name": "newborn infants",
"pos": [
235,
250
]
} |
vasculitis is rare in childhood , apart from henoch-schonlein purpura , and paediatric nephrologists see few cases of wegener 's granuloma or microscopic polyarteritis . | nichd_parent_of | {
"id": "C0042384",
"name": "vasculitis",
"pos": [
0,
10
]
} | {
"id": "C2347126",
"name": "microscopic",
"pos": [
142,
153
]
} |
in summary , the newer immunologic methods discussed in this paper have proven useful for advancing our understanding of disease pathogenesis in several epidermal and subepidermal blistering diseases of the skin . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
121,
128
]
} | {
"id": "C0037274",
"name": "diseases of",
"pos": [
191,
202
]
} |
in cardiovascular diseases such as hypertension , drug therapy may improve survival and the drug of choice is the one that interferes least with health-related well-being , otherwise known as the quality of life . | nichd_parent_of | {
"id": "C0007222",
"name": "cardiovascular diseases",
"pos": [
3,
26
]
} | {
"id": "C0020538",
"name": "hypertension",
"pos": [
35,
47
]
} |
in students ( men ) of the 2nd course maximum oxygen uptake and some physiological features ( rest systolic rate , vital lung capacity , the strength of flexors of both hands ) and somatic ones ( body weight , height ) specific to a marked degree of physical fitness were assessed . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
83,
91
]
} | {
"id": "C0005910",
"name": "body weight",
"pos": [
196,
207
]
} |
after assessment for tumour response , autologous bone marrow ( abm ) was collected from five patients in good clinical state who had shown a partial response ( pr ) and no bone marrow involvement with tumour . | nichd_parent_of | {
"id": "C0027651",
"name": "tumour",
"pos": [
21,
27
]
} | {
"id": "C0282609",
"name": "bone marrow",
"pos": [
173,
184
]
} |
the characteristics of this condition include a cleft spine revealed by plain x-ray , vesicorectal disturbances , local findings ( such as a tumor , dimpling , and angioma in the lumbosacral region ) , and deformities of the feet . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
141,
146
]
} | {
"id": "C0018916",
"name": "angioma",
"pos": [
164,
171
]
} |
lumbar nerve root anesthesia using a local anesthetic was performed in 100 cases of sciatica . | nichd_parent_of | {
"id": "C0002903",
"name": "anesthesia",
"pos": [
18,
28
]
} | {
"id": "C0002921",
"name": "local anesthetic",
"pos": [
37,
53
]
} |
possession of the antigen hla b27 affects severity and prognosis of the arthritis and is more often associated with spondylitis and reiter 's syndrome . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
72,
81
]
} | {
"id": "C0038012",
"name": "spondylitis",
"pos": [
116,
127
]
} |
histopathological features were bilateral spheroid formation in specific brain stem nuclei and in the dorsal horn ( especially in and about clarke 's column ) along the length of the spinal cord . | nichd_parent_of | {
"id": "C1521970",
"name": "features",
"pos": [
18,
26
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
169,
175
]
} |
neoplasms were found in 85 % of rats from the tb group compared with 11 % in the lb group while only a single tumour ( a haemangioma of the uterus ) was observed in the controls . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasms",
"pos": [
0,
9
]
} | {
"id": "C0018916",
"name": "haemangioma",
"pos": [
121,
132
]
} |
characteristics measured , including age , weight , scrotal circumference , and reaction time , were all unrelated to bulls serving capacity in both experiments , as well as to breeding soudness examination scores for bulls in experiment 1 . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
0,
15
]
} | {
"id": "C0005910",
"name": "weight",
"pos": [
43,
49
]
} |
this study was conducted to assess the effects of endophyte-infected acremonium coenophialum tall fescue ( ky-31 ) seed ( 80 % infected ) on lactation in cd-1 dams and suckling performance of pups as measured by pup survival and growth rates . | nichd_parent_of | {
"id": "C0004927",
"name": "conducted",
"pos": [
15,
24
]
} | {
"id": "C0006147",
"name": "lactation",
"pos": [
141,
150
]
} |
a pilot research program conducted on 195 adolescents aged 14 to 18 shows a number of significant correlations between quantitative and qualitative aspects of friendships and various aspects of mental health , the number of friends and of close friends as well as the quality of interactions and the degree of intimacy lead to positive correlations with various signs such as emotional wavelength , control of one 's environment and absence of psychopathological symptoms . | nichd_parent_of | {
"id": "C0205556",
"name": "qualitative",
"pos": [
136,
147
]
} | {
"id": "C0018684",
"name": "health",
"pos": [
201,
207
]
} |
during the 10 years , modifications of the surgical procedure and myocardial preservation were introduced ( ie , complete resection of the pulmonary trunk made anastomosis easier ; since 1982 , cardioplegia in both coronary systems has been used , and left atrial-to-aortic assistance was introduced ) . | nichd_parent_of | {
"id": "C0543467",
"name": "surgical procedure",
"pos": [
43,
61
]
} | {
"id": "C0015250",
"name": "complete resection",
"pos": [
113,
131
]
} |
headache and especially migraine , with incidences of up to 50 % and 10 % , respectively , are the most common painful conditions to be treated in the pediatric age group . | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
0,
8
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
24,
32
]
} |
the criteria for interpreting these phenomena in the context of migraine disorder , even if they are not accompanied by headache , are : the reaction to migraine therapy ; | nichd_parent_of | {
"id": "C0018681",
"name": "headache",
"pos": [
120,
128
]
} | {
"id": "C0149931",
"name": "migraine",
"pos": [
153,
161
]
} |
by transverse ultrathin serial sections , precise measurements where made on the following cytological characteristics : the length , diameter and average number by unit surface area for the myofilaments ; | nichd_parent_of | {
"id": "C1521970",
"name": "characteristics",
"pos": [
103,
118
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
125,
131
]
} |
when a finding of either heterophilia or hyper-fibrinogenaemia was taken into account , the number of samples in which the diagnosis was confirmed was increased to 77 % . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
7,
14
]
} | {
"id": "C0011900",
"name": "diagnosis",
"pos": [
123,
132
]
} |
entero-like virus was mainly found in the first two weeks of life , whilst reovirus and rotavirus were principally found from the second week on . | nichd_parent_of | {
"id": "C0042776",
"name": "virus",
"pos": [
12,
17
]
} | {
"id": "C0035870",
"name": "rotavirus",
"pos": [
88,
97
]
} |
in 116 cases ( 31 % ) viruses were isolated or detected , consisting of 25 reo-viruses , 17 rotaviruses , 14 adenoviruses plus demonstration of haemorrhagic enteritis virus antigen in the spleens of 15 birds , eight pox-viruses , 19 duck enteritis herpesviruses and six other avian herpes-viruses , four duck hepatitis viruses , six other enterovirus-like isolates , two duck astroviruses and two avian infectious bronchitis viruses . | nichd_parent_of | {
"id": "C0042776",
"name": "viruses",
"pos": [
22,
29
]
} | {
"id": "C0035870",
"name": "rotaviruses",
"pos": [
92,
103
]
} |
accuracy of the systems was evaluated by comparison with quantitative procedures , and to check agreement between methods yielding semi-quantitative and quantitative results , ranges of acceptability were defined , based on the criteria reported in a previous paper [ 2 ] . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
57,
69
]
} | {
"id": "C1514721",
"name": "ranges",
"pos": [
176,
182
]
} |
quantitative chromatographic analysis was possible for a variety of sample types over a wide range of metal-ion concentrations . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
0,
12
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
93,
98
]
} |
characteristic rapid death of pines after infection by bursaphelenchus xylophilus suggests the involvement of phytotoxins in the pine wilt disease syndrome . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
139,
146
]
} | {
"id": "C0039082",
"name": "syndrome",
"pos": [
147,
155
]
} |
although there are numerous analytical methods available to evaluate physical and chemical properties of these compounds , there remains a demand for a qualitative method for the determination of the carbon chain length composition . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
"pos": [
60,
68
]
} | {
"id": "C0031809",
"name": "physical",
"pos": [
69,
77
]
} |
in our computations , a plane wave is propagated through the gain medium with weak turbulences , under the assumption that the size of the first fresnel zone is much smaller than the characteristic length of turbulences . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
183,
197
]
} | {
"id": "C1444754",
"name": "length",
"pos": [
198,
204
]
} |
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