text stringlengths 57 1.72k | relation stringclasses 125
values | h dict | t dict |
|---|---|---|---|
13 children were infants , 9 were already older than a year , thus , clearly deviating from the age structure reported in literature . | nichd_parent_of | {
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"name": "children",
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} | {
"id": "C0021270",
"name": "infants",
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despite of its many advantages this method should in future only be practised in old people and children or in cases without the hill-sachs- and the bankart-lesion . | nichd_parent_of | {
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} | {
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"name": "children",
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authors believe that the familiarity with this kind of procedure and the prompt decision to perform it before a further worsening of the clinical conditions have a positive influence on its results and that surgical indication should not be limited to the patients in cardiac arrest , but instead extended to those cases showing rapid deterioration of the clinical state . | nichd_parent_of | {
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however other indications emerged from this research , such as female sterility , pelvic vascular disease , climaterie syndrome and post-operatory affects . | nichd_parent_of | {
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} | {
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no patient developed clinical signs of disseminated intravascular coagulation following ascites infusion and in six patients where coagulation variables were studed , there were no signs of a consumption coagulopathy . | nichd_parent_of | {
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} | {
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in patients who were symptom-free during the recording , sinus arrests exceeding 2.5 seconds seemed to be a valuable finding to support the cardiac aetiology of the syncopal symptoms , whereas the diagnostic value of second degree av block with either wenckebach or mobitz ii like patterns , as such , and of ventricular tachycardia remained mostly unsettled . | nichd_parent_of | {
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we conclude that the detection of fn in the scleroderma skin is an useful marker of the activity of the systemic sclerosis process and we discuss the possible role of fn as a primary matrix for organization of the collagenous connective tissue during the sclerosing process . | nichd_parent_of | {
"id": "C0011644",
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} | {
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organisms capable of dissimilatory nitrate reduction are widely distributed among eubacterial groups defined by 16s ribosomal rna phylogeny . | nichd_parent_of | {
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} | {
"id": "C0004611",
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a disturbance of lipid metabolism could be the cause of this cardiac and skeletal muscle disease , but the reduced pct activity could be a sign of more diffuse myocardial disease as suggested by the fibrous lesions and vascular abnormalities observed in our cases . | nichd_parent_of | {
"id": "C0026848",
"name": "skeletal muscle disease",
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} | {
"id": "C0878544",
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in both diseases ( idiopathic gn and gn related to systemic diseases ) a good correlation was found between clinical-ordinary activity and immunological parameters such as circulating immune complexes and complement breakdown products . | nichd_parent_of | {
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} | {
"id": "C0442893",
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high grade ventricular arrhythmias ( 3 , 4a , 4b ) were observed in 5 patients ( 31 % ) , and minor arrhythmias ( grades 1 and 2 ) in 7 ( 44 % ) , while 4 patients ( 25 % ) showed no ventricular arrhythmia . | nichd_parent_of | {
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} | {
"id": "C0085612",
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human lens cells from 5-91-year old individuals were cultured in 8 different basal media containing fetal bovine , adult bovine , rabbit or human serum or human plasma or in a serum-containing medium supplemented with insulin , epidermal growth factor , fibroblast growth factor plus other hormones or trace elements . | nichd_parent_of | {
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} | {
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the latter is seen only in lesions derived from fibrous-histiocytic and synovial cells , a finding which may be of diagnostic use . | nichd_parent_of | {
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} | {
"id": "C0011900",
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} |
the association between gene deletion and a normal growth pattern in this individual indicates that hcs and any other peptide hormones encoded by the variant hgh and the other related gene ( s ) that are deleted in this individual are not required for fetal or extrauterine growth . | nichd_parent_of | {
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} | {
"id": "C0015965",
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} |
at 30 mg/kg/day several deaths and clinical signs , including ataxia , decreased activity , dyspnea and jerking movements after dosing , were observed . | nichd_parent_of | {
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} | {
"id": "C0013404",
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} |
sixty patients had atrial arrhythmias ( 29 atrial fibrillation , 2 atrial flutter , 22 atrial tachycardia , 7 premature atrial contractions ) and 4 patients had ventricular arrhythmias ( 1 ventricular tachycardia , 1 ventricular flutter , 2 premature ventricular contractions ) . | nichd_parent_of | {
"id": "C0085612",
"name": "ventricular arrhythmias",
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]
} | {
"id": "C0042514",
"name": "ventricular tachycardia",
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} |
although the peripheral administration of dsip ( delta sleep inducing peptide ) to intact animals does not consistently induce behavioral sleep , potentiation of the effect by d-amphetamine has been established earlier . | nichd_parent_of | {
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"name": "behavioral",
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137
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} | {
"id": "C0037313",
"name": "sleep",
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} |
these data strongly suggest that the humoral factor responsible for hypercalcemia in patients with head and neck cancer is not parathyroid hormone , and that patients with hyperparathyroidism can now be distinguished with confidence from those with malignancy-associated hypercalcemia . | nichd_parent_of | {
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} | {
"id": "C0149911",
"name": "malignancy-associated hypercalcemia",
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249,
284
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} |
this type of antibody ( iga ) is the body 's key defense against infections by these microbes : development of a rapid and specific iga response is the most important factor in the outcome of infections by viruses such as genital herpes type ii and infections by intracellular bacterial pathogens that are currently resistant to treatment by antibiotics . | nichd_parent_of | {
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]
} | {
"id": "C0004623",
"name": "infections",
"pos": [
249,
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} |
this prospective study was designed to determine whether it is possible to visualize cerclage suture material by ultrasound and to evaluate the clinical usefulness of ultrasound examination after cervical cerclage during pregnancy . | nichd_parent_of | {
"id": "C0220825",
"name": "evaluate",
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} | {
"id": "C0031809",
"name": "clinical",
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} |
out-patient anaesthesia generally comprises a higher risk than the surgical procedure itself , because there is no anaesthetic procedure adapted to ambulatory surgery besides local anaesthesia . | nichd_parent_of | {
"id": "C0002903",
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} | {
"id": "C0002921",
"name": "local anaesthesia",
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} |
for most of these disorders , demonstration of the enzymatic deficiency has led to accurate diagnosis of affected individuals recognition of variant and atypical forms , detection of carriers and prenatal diagnosis of affected fetuses . | nichd_parent_of | {
"id": "C0027361",
"name": "individuals",
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114,
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} | {
"id": "C0015965",
"name": "fetuses",
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227,
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} |
this review summarizes the clinical findings , radiological abnormalities and laboratory data which are indispensable for diagnosis . | nichd_parent_of | {
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} | {
"id": "C0011900",
"name": "diagnosis",
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} |
in a two years screening carried out on florentine children we confirmed that rotaviruses are the most important ethiological agents of acute gastroenteritis in infants less than two years old , irrespective of sex . | nichd_parent_of | {
"id": "C0008059",
"name": "children",
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} | {
"id": "C0021270",
"name": "infants",
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168
]
} |
the agent has been clearly demonstrated to be an effective diuretic in the treatment of edema due to cardiac disease ( congestive heart failure ) and edema , with or without ascites , due to hepatic disease . | nichd_parent_of | {
"id": "C0018799",
"name": "cardiac disease",
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116
]
} | {
"id": "C0018802",
"name": "congestive heart failure",
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} |
bumetanide has also been shown effective in treating edema due to renal disease , even when modest to severe renal insufficiency is present , and it may be useful in the treatment of edema refractory to other loop diuretics . | nichd_parent_of | {
"id": "C0022658",
"name": "renal",
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} | {
"id": "C0035078",
"name": "renal insufficiency",
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} |
the girdlestone procedure was performed in 36 cases of septic arthritis of the hip , most of which arose following operation . | nichd_parent_of | {
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} | {
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"name": "operation",
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} |
2 ) diseases met at any age but more severe in the aged , e.g . respiratory diseases ; | nichd_parent_of | {
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"pos": [
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12
]
} | {
"id": "C0035204",
"name": "respiratory",
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} |
the organism may be corynebacterium pyogenes , which is a pathogen of certain livestocks and is found in soil . | nichd_parent_of | {
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12
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} | {
"id": "C0450254",
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} |
the most cases of acquired b ag result from neoplasic diseases or infection with enterobacteriacea . | nichd_parent_of | {
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62
]
} | {
"id": "C0009450",
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} |
an immunohistological study was made of immunoglobulin-containing cells and antibody-containing cells in abscesses/granulomas which formed at the injection site , draining popliteal nodes and contralateral popliteal nodes of sheep given either a living staphylococcus aureus vaccine ( group l ) , a killed s. aureus vaccine with freund 's complete adjuvant ( fca ) ( group k ) or fca alone ( group c ) . | nichd_parent_of | {
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]
} | {
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299,
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} |
the chd group included tetralogy of fallot ( tf ) , patent ductus arteriosus ( pda ) , pulmonic stenosis ( ps ) , atrial septal defect ( asd ) and ventricular septal defect ( vsd ) . | nichd_parent_of | {
"id": "C0152021",
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]
} | {
"id": "C0039685",
"name": "tetralogy of fallot",
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} |
the chd group included tetralogy of fallot ( tf ) , patent ductus arteriosus ( pda ) , pulmonic stenosis ( ps ) , atrial septal defect ( asd ) and ventricular septal defect ( vsd ) . | nichd_parent_of | {
"id": "C0152021",
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"pos": [
4,
7
]
} | {
"id": "C0013274",
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} |
it is argued that choices involving sample , format , and procedure for examining satisfaction may influence the results of such research , and must be considered when creating or evaluating these efforts . | nichd_parent_of | {
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} | {
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} |
the procedure was evaluated by comparing presenting and post-treatment symptoms for each patient and by asking each patient to rate the effectiveness of the treatment . | nichd_parent_of | {
"id": "C0184661",
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4,
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} | {
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} |
in order to evaluate the possibility of early detection of minimal cerebral damages in the professional boxers , ten young pugilists were submitted to complete neurological examination , eeg recording and ct-scan . | nichd_parent_of | {
"id": "C0220825",
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20
]
} | {
"id": "C0027853",
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160,
184
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} |
experiments investigating the effect of substances implicated in folate malabsorption were analyzed in terms of the catenary model for folic acid absorption , in order to investigate their effects on the transfer rate constants free from the complicating effects on fluid movement . | nichd_parent_of | {
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} | {
"id": "C0005889",
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266,
271
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} |
both infections by potentially pathogenic microbes -- most of endogenous origin -- as well as infections by a number of different pathogenic bacterial species could effectively be prevented by selective decontamination ( sd ) . | nichd_parent_of | {
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15
]
} | {
"id": "C0004623",
"name": "infections",
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104
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} |
after mmr vaccination , 98 % ( 59/60 ) of children showed seroconversion by the measles hi test , 98 % ( 65/66 ) showed seroconversion by the rubella hi test and 57 % ( 34/60 ) showed seroconversion by mumps nt . | nichd_parent_of | {
"id": "C0022885",
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95
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} | {
"id": "C0549163",
"name": "rubella",
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142,
149
]
} |
information on the risk of tuberculous infection in the netherlands has been linked with information on the incidence of tuberculosis , in an attempt to estimate the risks of developing the disease following infection or reinfection . | nichd_parent_of | {
"id": "C0012634",
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190,
197
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} | {
"id": "C0009450",
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223,
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} |
qualitative differences in the dermal response to tuberculin in patients with active pulmonary disease and healthy tuberculin-positive individuals . | nichd_parent_of | {
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11
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} | {
"id": "C0018684",
"name": "healthy",
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107,
114
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} |
this procedure entails surgical entry into the anterior chamber from beneath either a conjunctival or a scleral flap in such a way as to completely cauterize any neovascular tissue in the iridocorneal angle and to permit adequate drainage of the aqueous fluid from the anterior chamber to the periocular space . | nichd_parent_of | {
"id": "C0184661",
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5,
14
]
} | {
"id": "C0543467",
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} |
if the eye is relatively quiet and has some visual reserve but an exceedingly high and intractable intraocular pressure , it is advisable to use either the carbon dioxide laser trabeculostomy procedure or the carbon dioxide laser trabeculo-sclerostomy operation as described . | nichd_parent_of | {
"id": "C0184661",
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201
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} | {
"id": "C0543467",
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} |
( 4 ) as the neoplasm grows , its leading downward edge would eventually penetrate the muscularis mucosae , and the malignant behavior of the neoplasm becomes apparent with further invasion into the submucosa , muscularis externa and serosa . | nichd_parent_of | {
"id": "C0027651",
"name": "neoplasm",
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21
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} | {
"id": "C0006826",
"name": "malignant",
"pos": [
116,
125
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} |
of 3010 people from three areas in zambia who had tuberculin tests performed , 24 % of adults and 9 % of children complained of chronic coughs . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
8,
14
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
105,
113
]
} |
the tuberculosis prevalence rate in people over 9 based on finding typical mycobacteria in the sputum was 5.32 per thousand , and in children ( based on large tuberculin reactions ) 5.60 per thousand . | nichd_parent_of | {
"id": "C0027361",
"name": "people",
"pos": [
36,
42
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
133,
141
]
} |
the reactive effects of three self-monitoring procedures were evaluated with respect to compliance with the self-monitoring requirements and session attendance . | nichd_parent_of | {
"id": "C0184661",
"name": "procedures",
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46,
56
]
} | {
"id": "C0220825",
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} |
it is advisable knowing the individual response to theophylline for managing episodes of asthma in children , that can be made by only one determination 2 hours after ingestion . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
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28,
38
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
99,
107
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} |
the effects of the plasma exchange on blood components and side effects during the procedure were evaluated . | nichd_parent_of | {
"id": "C0184661",
"name": "procedure",
"pos": [
83,
92
]
} | {
"id": "C0220825",
"name": "evaluated",
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98,
107
]
} |
the composition of walls isolated from organisms grown with the antibiotic was similar to that of walls from untreated bacteria . | nichd_parent_of | {
"id": "C0029235",
"name": "organisms",
"pos": [
39,
48
]
} | {
"id": "C0004611",
"name": "bacteria",
"pos": [
119,
127
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} |
the infections were 3 of acute bronchitis , 2 cases of asthmatic bronchitis , 6 of acute pneumonia , 1 of mycoplasma pneumonia , 2 of sepsis ( 1 accompanied with pneumonia ) , 3 of vacterial meningitis , 2 of urinary tract infection , 1 of acute appendicitis , 1 of aseptic meningitis and 1 of fever of undetermined origin . | nichd_parent_of | {
"id": "C0025289",
"name": "meningitis",
"pos": [
191,
201
]
} | {
"id": "C0025290",
"name": "aseptic",
"pos": [
266,
273
]
} |
one hundred forty-seven tumor specimens from 106 patients with various malignancies were placed in culture . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
24,
29
]
} | {
"id": "C0006826",
"name": "malignancies",
"pos": [
71,
83
]
} |
the colony-forming rates of various malignancies are as follows : breast cancer 14/15 ( 93 % ) , ovarian cancer 8/10 ( 80 % ) , stomach cancer 5/13 ( 38 % ) , sarcoma 4/5 ( 80 % ) , lung cancer 1/4 ( 25 % ) , colon cancer 3/3 , each of pancreas cancer , leukemia and primary unknown adenocarcinoma 2/2 , malignant lymphoma 1/1 . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
36,
48
]
} | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
159,
166
]
} |
the colony-forming rates of various malignancies are as follows : breast cancer 14/15 ( 93 % ) , ovarian cancer 8/10 ( 80 % ) , stomach cancer 5/13 ( 38 % ) , sarcoma 4/5 ( 80 % ) , lung cancer 1/4 ( 25 % ) , colon cancer 3/3 , each of pancreas cancer , leukemia and primary unknown adenocarcinoma 2/2 , malignant lymphoma 1/1 . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancies",
"pos": [
36,
48
]
} | {
"id": "C0024299",
"name": "malignant lymphoma",
"pos": [
304,
322
]
} |
the most marked progress in diagnostic procedures in this field seems to be several imaging techniques such as scintiphotography , u.s. echography and computed tomography . | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic",
"pos": [
28,
38
]
} | {
"id": "C0041618",
"name": "echography",
"pos": [
136,
146
]
} |
malignancy and antigenicity of fibrosarcoma meth 1 cells induced in a balb/c mouse were compared with sarcoma meth a cells . | nichd_parent_of | {
"id": "C0006826",
"name": "malignancy",
"pos": [
0,
10
]
} | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
102,
109
]
} |
unlabelled : this multicentered , placebo-controlled trial evaluated the efficacy of medical therapy to stop bleeding in 285 patients with active upper gastrointestinal bleeding ( bleeding phase ) and 194 patients who had ceased gastrointestinal bleeding and in whom therapy was instituted to prevent rebleeding during the same hospitalization ( prevention phase ) . | nichd_parent_of | {
"id": "C0019080",
"name": "bleeding",
"pos": [
109,
117
]
} | {
"id": "C0017181",
"name": "gastrointestinal bleeding",
"pos": [
229,
254
]
} |
candida species , aspergillus species , phycomyces , and cryptococcus neoformans remain most common , but other organisms are being encountered as pathogens . | nichd_parent_of | {
"id": "C0029235",
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"pos": [
112,
121
]
} | {
"id": "C0450254",
"name": "pathogens",
"pos": [
147,
156
]
} |
cyclophosphamide-prednisone therapy successfully controlled the extra-renal manifestations of their disease and reversed the renal failure so that dialysis could be discontinued . | nichd_parent_of | {
"id": "C0022658",
"name": "renal",
"pos": [
70,
75
]
} | {
"id": "C0035078",
"name": "renal failure",
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125,
138
]
} |
originally described as a de novo disease of unknown etiology , a histiocytic medullary reticulosis-like syndrome has been more recently found in association with a number of other disorders , the majority being lymphoreticular neoplasms . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
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190
]
} | {
"id": "C0027651",
"name": "neoplasms",
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228,
237
]
} |
in the control pregnancies , the rate of induction of labor was 13.81 % compared with 39.84 % in the prolonged pregnancies . | nichd_parent_of | {
"id": "C0032961",
"name": "pregnancies",
"pos": [
15,
26
]
} | {
"id": "C0032993",
"name": "prolonged pregnancies",
"pos": [
101,
122
]
} |
among primiparous patients , cesarean delivery for `` '' failure to progress '' '' was performed in 14 % of electively induced labors and 7 % of spontaneous control labors , a difference not noted among multiparous patients who had a primary cesarean birth rate of less than 2 % . | nichd_parent_of | {
"id": "C0007876",
"name": "cesarean delivery",
"pos": [
29,
46
]
} | {
"id": "C3828478",
"name": "a primary cesarean bir",
"pos": [
232,
254
]
} |
our conclusion is that patients who require an induction of labor , when artificial rupture of the membranes is not feasible , benefit from the use of prostaglandin pessaries before the administration of oxytocin . | nichd_parent_of | {
"id": "C0259787",
"name": "induction of labor",
"pos": [
47,
65
]
} | {
"id": "C0177273",
"name": "artificial rupture of",
"pos": [
73,
94
]
} |
y-chromatin positivity ( indicating gamete heterozygosity ) was found in 16 of 182 cases ( 9 % ) of hydatidiform mole , two of four cases ( 50 % ) of invasive mole , and 14 of 19 cases ( 74 % ) of choriocarcinoma . | nichd_parent_of | {
"id": "C0020217",
"name": "hydatidiform mole",
"pos": [
100,
117
]
} | {
"id": "C0008493",
"name": "invasive mole",
"pos": [
150,
163
]
} |
this finding is consistent with reports of low levels of csf 5-hiaa in suicidal patients with other psychiatric diagnoses and suggests that low csf 5-hiaa may be a generalized marker of aggressive behavior against the self and others . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
5,
12
]
} | {
"id": "C0011900",
"name": "diagnoses",
"pos": [
112,
121
]
} |
fifty-six patients had germ cell tumors and 7 epithelial tumors , 6 patients had bilateral tumors , 47 patients had teratomas ( 41 benign , 3 with embryonic tissue , and 3 malignant ) , 6 germinomas , 1 endodermal sinus tumor , and 2 mixed germ cell tumors . | nichd_parent_of | {
"id": "C0205851",
"name": "germ cell tumors",
"pos": [
23,
39
]
} | {
"id": "C0039538",
"name": "teratomas",
"pos": [
116,
125
]
} |
fifty-six patients had germ cell tumors and 7 epithelial tumors , 6 patients had bilateral tumors , 47 patients had teratomas ( 41 benign , 3 with embryonic tissue , and 3 malignant ) , 6 germinomas , 1 endodermal sinus tumor , and 2 mixed germ cell tumors . | nichd_parent_of | {
"id": "C0205851",
"name": "germ cell tumors",
"pos": [
23,
39
]
} | {
"id": "C0206660",
"name": "germinomas",
"pos": [
188,
198
]
} |
eighty-three percent of those limbs with deep posterior compartment pressures above 30 mmhg had objective clinical signs of venous insufficiency , namely edema , stasis dermatitis and/or stasis ulcer . | nichd_parent_of | {
"id": "C3540840",
"name": "clinical signs",
"pos": [
106,
120
]
} | {
"id": "C0013604",
"name": "edema",
"pos": [
154,
159
]
} |
in order to determine the role of epidural anaesthesia on protein sparing , eighteen patients undergoing major visceral surgery were randomly divided into three different groups according to the mode of anaesthesia used ( general anaesthesia , epidural anaesthesia , continuous epidural anaesthesia for 24 h ) . | nichd_parent_of | {
"id": "C0002903",
"name": "anaesthesia",
"pos": [
43,
54
]
} | {
"id": "C0002915",
"name": "general",
"pos": [
222,
229
]
} |
a randomized , double-blinded study was conducted to evaluate the effectiveness of the calcium antagonist verapamil in patients in cardiopulmonary arrest with asystole or pulseless idioventricular rhythm ( pivr ) . | nichd_parent_of | {
"id": "C0600228",
"name": "cardiopulmonary arrest",
"pos": [
131,
153
]
} | {
"id": "C0018790",
"name": "asystole",
"pos": [
159,
167
]
} |
forty nictitating membrane glands and 9 main lacrimal glands were obtained for histologic evaluation from 28 dogs with keratoconjunctivitis sicca as the result of azosulfapyridine toxicity , canine distemper , multisystemic autoimmune disease ( sjogren 's syndrome-like syndrome ) , congenital origin , and unilateral and bilateral idiopathic keratoconjunctivitis sicca . | nichd_parent_of | {
"id": "C0004364",
"name": "autoimmune disease",
"pos": [
224,
242
]
} | {
"id": "C1527336",
"name": "sjogren 's syndrome",
"pos": [
245,
264
]
} |
in this clinical study , the role of enfenamic acid ( tromaril ) , a new anti-inflammatory and nonsteroidal drug , on various eye diseases such as trauma , on inflammatory diseases such as uveitis , and after cataract surgery was evaluated . | nichd_parent_of | {
"id": "C0015397",
"name": "eye diseases",
"pos": [
126,
138
]
} | {
"id": "C0042164",
"name": "uveitis",
"pos": [
189,
196
]
} |
when the overall goodness-of-fit to height data of polynomials in age was examined , for children measured on 7 or 8 occasions , it was found that cubic polynomials were necessary to describe the growth of boys and girls over the age range 5.0 to 11.0 years , but that cubic and quadratic coefficients could not be interpreted for individual children . | nichd_parent_of | {
"id": "C0027361",
"name": "individual",
"pos": [
331,
341
]
} | {
"id": "C0008059",
"name": "children",
"pos": [
342,
350
]
} |
stage i disease is defined as tumor confined to the resected portion of the liver without invasion of major intrahepatic vessels or bile ducts . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
8,
15
]
} | {
"id": "C0027651",
"name": "tumor",
"pos": [
30,
35
]
} |
fifteen patients ( 42.8 % ) had venous thrombosis , and arterial thrombosis manifested by stroke or transient ischemic attacks occurred in six patients . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
90,
96
]
} | {
"id": "C0007787",
"name": "transient ischemic attacks",
"pos": [
100,
126
]
} |
the 9 germ cell tumors in autopsies were seminomas ( 2 ) , embryonal carcinomas ( 3 ) , choriocarcinomas ( 2 ) and choriocarcinomas with embryonal carcinoma ( 2 ) . | nichd_parent_of | {
"id": "C0205851",
"name": "germ cell tumors",
"pos": [
6,
22
]
} | {
"id": "C0036631",
"name": "seminomas",
"pos": [
41,
50
]
} |
on the use of discrimination of level differences as a diagnostic test procedure as suggested by fastl and schorn ( 1981 ) | nichd_parent_of | {
"id": "C0430022",
"name": "diagnostic",
"pos": [
55,
65
]
} | {
"id": "C0022885",
"name": "test",
"pos": [
66,
70
]
} |
in addition , these mice have elevated levels of rheumatoid factor and spontaneously develop arthritis that has many similarities to human rheumatoid arthritis . | nichd_parent_of | {
"id": "C0003864",
"name": "arthritis",
"pos": [
93,
102
]
} | {
"id": "C0003873",
"name": "rheumatoid arthritis",
"pos": [
139,
159
]
} |
these three cases appear to represent a rare leukaemia subtype that we have designated acute leukaemia with mixed lymphoid and myeloid phenotype . | nichd_parent_of | {
"id": "C0023418",
"name": "subtype",
"pos": [
55,
62
]
} | {
"id": "C0023449",
"name": "acute leukaemia",
"pos": [
87,
102
]
} |
the concentration of 13,14-dihydro-15-keto-pge2 ( pgem ) was measured by radioimmunoassay in pregnant women in the third trimester , in women at term but not in labour and during labour of spontaneous onset . | nichd_parent_of | {
"id": "C0022864",
"name": "labour",
"pos": [
161,
167
]
} | {
"id": "C0474461",
"name": "labour of spontaneous onset",
"pos": [
179,
206
]
} |
among the patients with endogenous uveitis the level was significantly raised in cases of anterior uveitis , but there was no change in cases of posterior uveitis . | nichd_parent_of | {
"id": "C0042164",
"name": "uveitis",
"pos": [
35,
42
]
} | {
"id": "C0042165",
"name": "anterior uveitis",
"pos": [
90,
106
]
} |
among the patients with endogenous uveitis the level was significantly raised in cases of anterior uveitis , but there was no change in cases of posterior uveitis . | nichd_parent_of | {
"id": "C0042164",
"name": "uveitis",
"pos": [
35,
42
]
} | {
"id": "C0042167",
"name": "posterior",
"pos": [
145,
154
]
} |
the 31p-nmr spectrum characteristic of phospholipid bilayers was observed at all temperatures both in the absence of ca2+ and in the presence of 10 mm and 50 mm ca2+ . | nichd_parent_of | {
"id": "C1521970",
"name": "characteristic",
"pos": [
21,
35
]
} | {
"id": "C0039476",
"name": "temperatures",
"pos": [
81,
93
]
} |
thus , the duration of depression following stroke is more than six months and the prevalence of major depressive symptoms increases steadily for the first half year after a cerebral hemorrhage or ischemic lesion . | nichd_parent_of | {
"id": "C0038454",
"name": "stroke",
"pos": [
44,
50
]
} | {
"id": "C2937358",
"name": "cerebral hemorrhage",
"pos": [
174,
193
]
} |
renal artery disease is not rare in this difficult group and finding seriously impaired renal function on one side during captopril treatment may be diagnostic . | nichd_parent_of | {
"id": "C0037088",
"name": "finding",
"pos": [
61,
68
]
} | {
"id": "C0011900",
"name": "diagnostic",
"pos": [
149,
159
]
} |
in order to compare within the same brains the quantitative distributions of a range of neuropeptides , bombesin , n- and c-terminal glucagon , cholecystokinin , neurotensin , somatostatin , substance p and vasoactive intestinal polypeptide immunoreactivities were determined by radioimmunoassay in 24 regions of 5 normal adult human brains . | nichd_parent_of | {
"id": "C0392762",
"name": "quantitative",
"pos": [
47,
59
]
} | {
"id": "C1514721",
"name": "range",
"pos": [
79,
84
]
} |
somatostatin produces apnea and is localized in medullary respiratory nuclei : a possible role in apneic syndromes . | nichd_parent_of | {
"id": "C0003578",
"name": "apnea",
"pos": [
22,
27
]
} | {
"id": "C0037315",
"name": "apneic syndromes",
"pos": [
98,
114
]
} |
the authors report the successful staged resection of a descending thoracic aortic aneurysm and a coexisting ascending aortic aneurysm . | nichd_parent_of | {
"id": "C0002940",
"name": "aneurysm",
"pos": [
83,
91
]
} | {
"id": "C0003486",
"name": "aortic aneurysm",
"pos": [
119,
134
]
} |
microscopic satellites were defined as tumor nests , greater than 0.05 mm in diameter , in the reticular dermis , panniculus , or vessels beneath the principal invasive tumor mass but separated from it by normal tissue on the section in which the breslow measurement was taken . | nichd_parent_of | {
"id": "C0027651",
"name": "tumor",
"pos": [
39,
44
]
} | {
"id": "C0577559",
"name": "mass",
"pos": [
175,
179
]
} |
in addition to the multinucleated giant cells and the prominent stromal angiogenesis reported in earlier reports , other characteristic features of the tumors were observed : ( 1 ) the gross appearance , characterized by a well-outlined , lump-shaped , dark brown tumor mass ; | nichd_parent_of | {
"id": "C0027651",
"name": "tumors",
"pos": [
152,
158
]
} | {
"id": "C0577559",
"name": "lump",
"pos": [
239,
243
]
} |
this result was obtained with the sa1 sarcoma , meth a fibrosarcoma , p815 mastocytoma , and p388 lymphoma . | nichd_parent_of | {
"id": "C1261473",
"name": "sarcoma",
"pos": [
38,
45
]
} | {
"id": "C0016057",
"name": "fibrosarcoma",
"pos": [
55,
67
]
} |
furthermore , submaximal doses of testosterone for growth plus chemotherapy induced a longer disease-free interval ( no palpable tumors by 120 days in 12 of 12 mice ) than did complete androgen withdrawal plus drugs ( palpable tumors in 4 of 5 mice by 104 +/- 2.7 days ) . | nichd_parent_of | {
"id": "C0012634",
"name": "disease",
"pos": [
93,
100
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
227,
233
]
} |
to test this hypothesis and to differentiate between er-mediated and general cytotoxic effects of tam , the growth-inhibitory effects of tam and its in vivo metabolite 4-hydroxytamoxifen ( oh-tam ) have been studied in five continuous human cancer cell lines , mcf7 and t47d ( mammary carcinoma , er positive ) , bt20 and mda-mb-231 ( mammary carcinoma , er negative ) , and me8 ( melanoma , er negative ) . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
241,
247
]
} | {
"id": "C0678222",
"name": "mammary carcinoma",
"pos": [
335,
352
]
} |
to test this hypothesis and to differentiate between er-mediated and general cytotoxic effects of tam , the growth-inhibitory effects of tam and its in vivo metabolite 4-hydroxytamoxifen ( oh-tam ) have been studied in five continuous human cancer cell lines , mcf7 and t47d ( mammary carcinoma , er positive ) , bt20 and mda-mb-231 ( mammary carcinoma , er negative ) , and me8 ( melanoma , er negative ) . | nichd_parent_of | {
"id": "C0006826",
"name": "cancer",
"pos": [
241,
247
]
} | {
"id": "C0025202",
"name": "melanoma",
"pos": [
381,
389
]
} |
thus , the deviations in s-ace in renal disorders seem to be discrete : depressed levels in acute renal failure and a relative depression in undialyzed patients with chronic renal disorders . | nichd_parent_of | {
"id": "C0022658",
"name": "renal disorders",
"pos": [
34,
49
]
} | {
"id": "C0022660",
"name": "acute renal failure",
"pos": [
92,
111
]
} |
thus , the deviations in s-ace in renal disorders seem to be discrete : depressed levels in acute renal failure and a relative depression in undialyzed patients with chronic renal disorders . | nichd_parent_of | {
"id": "C0022658",
"name": "renal disorders",
"pos": [
34,
49
]
} | {
"id": "C0022661",
"name": "chronic renal disorders",
"pos": [
166,
189
]
} |
( 4 ) the incidence of all chd events found during the follow-up study ( chd deaths , myocardial infarction , angina pectoris , and pathologic exercise ecgs ) was moderately but significantly lower in men with a prolonged pr than among men with a pr less than or equal to 0.21 s . | nichd_parent_of | {
"id": "C0018799",
"name": "the",
"pos": [
6,
9
]
} | {
"id": "C0027051",
"name": "myocardial infarction",
"pos": [
86,
107
]
} |
the differential diagnosis included congenital dislocation , neurovascular disorders , tumors of the forearm , and monteggia-type fracture-dislocation . | nichd_parent_of | {
"id": "C0012634",
"name": "disorders",
"pos": [
75,
84
]
} | {
"id": "C0027651",
"name": "tumors",
"pos": [
87,
93
]
} |
recent publications provide evidence that primary hypertension may have its inception in childhood or possibly in infancy . | nichd_parent_of | {
"id": "C0231335",
"name": "childhood",
"pos": [
89,
98
]
} | {
"id": "C0231330",
"name": "infancy",
"pos": [
114,
121
]
} |
available data also suggest that recent pertussis deaths in infants in england and wales may frequently be reported as due to respiratory diseases other than pertussis . | nichd_parent_of | {
"id": "C0035204",
"name": "respiratory diseases",
"pos": [
126,
146
]
} | {
"id": "C0043167",
"name": "pertussis",
"pos": [
158,
167
]
} |
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