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22 classes
Areas of fibrosis as well as hyperplasia or atrophy of the retinal pigment epithelium ( RPE ) also exhibited hypoautofluorescence .
{ "id": "C0035298", "pos": [ 59, 66 ], "name": "retinal" }
{ "id": "C0035322", "pos": [ 88, 91 ], "name": "RPE" }
0NA
Possible developmental relationships between these unusual anatomical findings in the conduction system and coarctation of the aorta are discussed .
{ "id": "C0003483", "pos": [ 127, 132 ], "name": "aorta" }
{ "id": "C0003492", "pos": [ 108, 119 ], "name": "coarctation" }
11finding_site_of
Given together TO and Ami provided 70 % protection to rats receiving Dex .
{ "id": "C0011816", "pos": [ 69, 72 ], "name": "Dex" }
{ "id": "C0027051", "pos": [ 22, 25 ], "name": "Ami" }
0NA
It is hypothesized that early identification of the absence or hypoplasia of the adenoids can result in the implementation of appropriate therapy plans to avoid severe disorders of speech intelligibility .
{ "id": "C0243069", "pos": [ 63, 73 ], "name": "hypoplasia" }
{ "id": "C0001428", "pos": [ 81, 89 ], "name": "adenoids" }
0NA
Patients ( n   =   208 ) using capecitabine ( 35 % ) , lenalidomide ( 15 % ) , imatinib ( 14 % ) , temozolomide ( 12 % ) , sunitinib ( 11 % ) , thalidomide ( 5 % ) , dasatinib ( 4 % ) , erlotinib ( 2 % ) , and nilotinib ( 2 % ) participated .
{ "id": "C1176020", "pos": [ 123, 132 ], "name": "sunitinib" }
{ "id": "C1721377", "pos": [ 210, 219 ], "name": "nilotinib" }
0NA
Based on the literature of psychophysical studies in simulated and real prosthetic vision , this paper proposes a comprehensive , theoretical training regime for a prosthesis recipient : visual search , visual acuity , reading , face/object recognition , hand-eye coordination and navigation .
{ "id": "C0175649", "pos": [ 164, 174 ], "name": "prosthesis" }
{ "id": "C0042812", "pos": [ 203, 216 ], "name": "visual acuity" }
0NA
Chronic pain and itch are common hypersensitivity syndromes that are affected by endogenous mediators .
{ "id": "C0150055", "pos": [ 0, 12 ], "name": "Chronic pain" }
{ "id": "C0033774", "pos": [ 17, 21 ], "name": "itch" }
0NA
These findings suggest that vitamin E may be an important lower respiratory tract antioxidant , and that the deficiency seen in young smokers may predispose them to an enhanced oxidant attack on their lung parenchymal cells .
{ "id": "C0024109", "pos": [ 201, 205 ], "name": "lung" }
{ "id": "C0035237", "pos": [ 64, 81 ], "name": "respiratory tract" }
0NA
para-aminohippurate , estrone sulfate , probenecid , furosemide , diclofenac , and cimetidine ) in cultures spanning 29 passage numbers revealed relevant inhibitory potencies , confirming the robustness of our model for drug-drug interactions studies .
{ "id": "C0012091", "pos": [ 66, 76 ], "name": "diclofenac" }
{ "id": "C0008783", "pos": [ 83, 93 ], "name": "cimetidine" }
0NA
The striatum is the key site for cortical input to the basal ganglia .
{ "id": "C0001613", "pos": [ 33, 41 ], "name": "cortical" }
{ "id": "C0010097", "pos": [ 4, 12 ], "name": "striatum" }
0NA
Platelet counts < 20,000 cells/mm(3 ) , were again significantly associated ( p<0.001 ) with severe disease ( odds ratio 1.632 to 455.2 , 95 % CI 3.089 to 14.71 ) .
{ "id": "C0012634", "pos": [ 100, 107 ], "name": "disease" }
{ "id": "C0032181", "pos": [ 0, 15 ], "name": "Platelet counts" }
0NA
Risk measures of these and other late sequelae , however , can vary markedly between investigations , depending on the types of treatment , the rigor with which epidemiologic study designs are applied , ascertainment of events of interest , the duration and completeness of follow-up , and consideration of competing risks .
{ "id": "C0026837", "pos": [ 144, 149 ], "name": "rigor" }
{ "id": "C1261322", "pos": [ 85, 99 ], "name": "investigations" }
0NA
Nine patients with primary LELC of the lung treated at a single institution with a multimodality approach comprised of surgery , chemotherapy , and radiotherapy are reported .
{ "id": "C0024109", "pos": [ 39, 43 ], "name": "lung" }
{ "id": "C0013216", "pos": [ 129, 141 ], "name": "chemotherapy" }
0NA
The early phase of the disease was characterized by excessive CO2 retention , tachypnea , and inability to tolerate reductions in IMV .
{ "id": "C0012634", "pos": [ 23, 30 ], "name": "disease" }
{ "id": "C0231835", "pos": [ 78, 87 ], "name": "tachypnea" }
0NA
Circadian pattern of arrhythmia and heart rate variability BPC ( mean , SDNN , SDAN-N-i , SDNN-i , rMSSD , pNN50 ) were compared to 3-hour values of Ap(Ar)-index of geomagnetic activity in the examination day in Moscow with estimation of the correlation coefficient ( r ) .
{ "id": "C0031809", "pos": [ 193, 204 ], "name": "examination" }
{ "id": "C0003811", "pos": [ 21, 31 ], "name": "arrhythmia" }
0NA
Limb salvage for management of osteosarcoma of the lower extremity has become the mainstay of treatment for patients with malignant bony and soft tissue tumors .
{ "id": "C0023216", "pos": [ 51, 66 ], "name": "lower extremity" }
{ "id": "C0037579", "pos": [ 141, 159 ], "name": "soft tissue tumors" }
0NA
Integrated traditional Chinese and western medicine treatment of AMI could reducing incidence of complications , such as arrhythmia , pump failure and thrombosis , and thrombolytic therapy could reduce mortality of patients .
{ "id": "C0040044", "pos": [ 168, 188 ], "name": "thrombolytic therapy" }
{ "id": "C0003811", "pos": [ 121, 131 ], "name": "arrhythmia" }
0NA
Abnormalities of the tendons of the foot and ankle are quite common and their number seems to be increasing .
{ "id": "C0000768", "pos": [ 0, 13 ], "name": "Abnormalities" }
{ "id": "C0039508", "pos": [ 21, 28 ], "name": "tendons" }
0NA
This modified technique is therefore suitable for the simultaneous demonstration of capillaries and fiber types in skeletal muscle .
{ "id": "C0242692", "pos": [ 115, 130 ], "name": "skeletal muscle" }
{ "id": "C0006901", "pos": [ 84, 95 ], "name": "capillaries" }
0NA
However , there were no observed differences by social class of the likelihood of a positive prostate specific antigen test or prostate cancer related death .
{ "id": "C0033572", "pos": [ 93, 101 ], "name": "prostate" }
{ "id": "C0376358", "pos": [ 127, 142 ], "name": "prostate cancer" }
11finding_site_of
To identify factors which contribute to upper limb recovery , from the perspective of stroke survivors .
{ "id": "C1140618", "pos": [ 40, 50 ], "name": "upper limb" }
{ "id": "C0038454", "pos": [ 86, 92 ], "name": "stroke" }
0NA
To improve overall influenza vaccination coverage and reduce racial/ethnic disparities , combinations of evidence-based effective interventions should be implemented , and the influenza vaccine supply should be stabilized .
{ "id": "C0021403", "pos": [ 176, 193 ], "name": "influenza vaccine" }
{ "id": "C0042200", "pos": [ 19, 40 ], "name": "influenza vaccination" }
10direct_substance_of
This combination therapy exhibited enhanced cytotoxic effects on pancreatic cancer both in vitro and in vivo .
{ "id": "C0304497", "pos": [ 44, 53 ], "name": "cytotoxic" }
{ "id": "C0235974", "pos": [ 65, 82 ], "name": "pancreatic cancer" }
0NA
Aneurysms of the popliteal vein represent a rare clinical finding .
{ "id": "C0002940", "pos": [ 0, 9 ], "name": "Aneurysms" }
{ "id": "C0032652", "pos": [ 17, 31 ], "name": "popliteal vein" }
0NA
We conclude that ASIC2a and -3 are the major ASIC subunits in cardiac dorsal root ganglia neurons and provide potential molecular targets to attenuate chest pain and deleterious reflexes associated with cardiac disease .
{ "id": "C0018787", "pos": [ 62, 69 ], "name": "cardiac" }
{ "id": "C0018799", "pos": [ 203, 218 ], "name": "cardiac disease" }
11finding_site_of
Thus , modified expression of cardiac MRP5 in septic shock can alter cGMP concentrations and contribute to the development of heart failure .
{ "id": "C0018787", "pos": [ 30, 37 ], "name": "cardiac" }
{ "id": "C0018801", "pos": [ 126, 139 ], "name": "heart failure" }
11finding_site_of
Twenty-four hours after ALI induction , rats were anesthetized and mechanically ventilated with VT=6 ml/kg and positive end-expiratory pressure (PEEP)=5 cmH(2)O for 1h .
{ "id": "C1446409", "pos": [ 111, 119 ], "name": "positive" }
{ "id": "C0242488", "pos": [ 24, 27 ], "name": "ALI" }
0NA
Undifferentiated ( embryonal ) sarcoma of the liver ( USL ) is a rare malignant tumour with a poor prognosis .
{ "id": "C0023884", "pos": [ 46, 51 ], "name": "liver" }
{ "id": "C0006826", "pos": [ 70, 86 ], "name": "malignant tumour" }
0NA
To observe the effects of combination of Lumbrukinase Capsule ( LC ) and Probucol Tablet ( PT ) in treating cerebral infarction ( CI ) patients ' unstable atheromatous plaque of the carotid artery .
{ "id": "C0264956", "pos": [ 155, 174 ], "name": "atheromatous plaque" }
{ "id": "C0007272", "pos": [ 182, 196 ], "name": "carotid artery" }
0NA
Our interests have focussed on three neoplastic entities in the kidney , renal mesenchymal neoplasia , renal cell carcinoma , and nephroblastoma .
{ "id": "C0022646", "pos": [ 64, 70 ], "name": "kidney" }
{ "id": "C0007134", "pos": [ 103, 123 ], "name": "renal cell carcinoma" }
11finding_site_of
The depolarization-induced burst response of the dorsal roots was greatly reduced after crush or transection of the sciatic nerve .
{ "id": "C0185060", "pos": [ 88, 93 ], "name": "crush" }
{ "id": "C0205955", "pos": [ 49, 61 ], "name": "dorsal roots" }
0NA
Foam cell lesions developed in the aorta proximal to the coarctation .
{ "id": "C0003483", "pos": [ 35, 40 ], "name": "aorta" }
{ "id": "C0003492", "pos": [ 57, 68 ], "name": "coarctation" }
11finding_site_of
The variables were found to differentially affect each ADL , highlighting two opposite aspects of institutionalization -- deterioration , on the one hand , and rehabilitation through intervention by highly trained staff , on the other .
{ "id": "C0184661", "pos": [ 183, 195 ], "name": "intervention" }
{ "id": "C0034991", "pos": [ 160, 174 ], "name": "rehabilitation" }
0NA
In addition these patients were dependent on RBC transfusions for significantly longer periods .
{ "id": "C0429964", "pos": [ 32, 41 ], "name": "dependent" }
{ "id": "C0014772", "pos": [ 45, 48 ], "name": "RBC" }
0NA
Until recently , MRSA has primarily been a problem associated with exposure to the healthcare system , especially in people with prolonged hospital admissions , with underlying disease , or after antibiotic use .
{ "id": "C0012634", "pos": [ 177, 184 ], "name": "disease" }
{ "id": "C0343401", "pos": [ 17, 21 ], "name": "MRSA" }
0NA
Unfortunately , natural aging and other vascular risk factors cause a decline in collateral number and diameter ( rarefaction ) and an increase in stroke severity .
{ "id": "C0001811", "pos": [ 24, 29 ], "name": "aging" }
{ "id": "C0038454", "pos": [ 147, 153 ], "name": "stroke" }
0NA
Perceived risk of asthma medications on the fetus was highest for corticosteroid-containing medication ; and was significantly reduced following education .
{ "id": "C0013227", "pos": [ 25, 36 ], "name": "medications" }
{ "id": "C0004096", "pos": [ 18, 24 ], "name": "asthma" }
0NA
This proximity may lead to foreign bodies to displace into the maxillary sinus and lead to development of infection .
{ "id": "C0016542", "pos": [ 27, 41 ], "name": "foreign bodies" }
{ "id": "C0009450", "pos": [ 106, 115 ], "name": "infection" }
0NA
Hormone replacement was also related to decreases in plasma norepinephrine .
{ "id": "C0032105", "pos": [ 53, 59 ], "name": "plasma" }
{ "id": "C0282402", "pos": [ 0, 19 ], "name": "Hormone replacement" }
0NA
In this issue of Blood , Bakchoul et al and Lee et al describe and characterize a common but only recently recognized immune response to protamine after cardiopulmonary bypass ( CPB ) surgery with potential important clinical implications .
{ "id": "C0005767", "pos": [ 17, 22 ], "name": "Blood" }
{ "id": "C0033603", "pos": [ 137, 146 ], "name": "protamine" }
0NA
Being in liquid form , it initially provides the advantage of in vivo placement by simple means , such as syringes to form implants at the site of use .
{ "id": "C0021107", "pos": [ 70, 79 ], "name": "placement" }
{ "id": "C0039142", "pos": [ 106, 114 ], "name": "syringes" }
0NA
A 69-year-old male patient with chronic obstructive pulmonary disease exhibited dose-dependent theophylline elimination .
{ "id": "C0039771", "pos": [ 95, 107 ], "name": "theophylline" }
{ "id": "C0086582", "pos": [ 14, 18 ], "name": "male" }
0NA
By promoting liver disease , chronic drinking has further detrimental effects on the kidneys , including impaired sodium and fluid handling and even acute kidney failure .
{ "id": "C0022646", "pos": [ 85, 92 ], "name": "kidneys" }
{ "id": "C0022660", "pos": [ 149, 169 ], "name": "acute kidney failure" }
11finding_site_of
These results suggest that a combination of climate factors and reduced intervention coverage in parts of the country contributed to both the reduction and rebound in malaria parasite prevalence .
{ "id": "C0024530", "pos": [ 167, 174 ], "name": "malaria" }
{ "id": "C0184661", "pos": [ 72, 84 ], "name": "intervention" }
0NA
Misoprostol reduced urea-N synthesis rate ( during fasting and in response to alanine ) , resulting in a positive nitrogen exchange .
{ "id": "C1446409", "pos": [ 105, 113 ], "name": "positive" }
{ "id": "C0085174", "pos": [ 0, 11 ], "name": "Misoprostol" }
0NA
An 8F urethral catheter is passed , the balloon is inflated and the peel away sheath is removed .
{ "id": "C0227952", "pos": [ 78, 84 ], "name": "sheath" }
{ "id": "C0237849", "pos": [ 68, 72 ], "name": "peel" }
0NA
The conventional neurological examination which assesses vibration sensation by utilizing a tuning fork is relatively insensitive for this purpose .
{ "id": "C0027853", "pos": [ 17, 41 ], "name": "neurological examination" }
{ "id": "C0036658", "pos": [ 67, 76 ], "name": "sensation" }
0NA
Immune response of regional lymph nodes was studied in 30 skin melanoma patients .
{ "id": "C0024204", "pos": [ 28, 39 ], "name": "lymph nodes" }
{ "id": "C0151779", "pos": [ 58, 71 ], "name": "skin melanoma" }
0NA
To reduce amputation rate of most severe pattern ( Type III ) of electrical burns of wrist .
{ "id": "C0002688", "pos": [ 10, 20 ], "name": "amputation" }
{ "id": "C0006436", "pos": [ 65, 81 ], "name": "electrical burns" }
0NA
In isolated preparations , AF-DX 116 has a tenfold higher affinity for the muscarine receptors of the heart ( pA2 7.33 ) than for those in smooth muscles ( pA2 6.39 - 6.44 ) .
{ "id": "C0018787", "pos": [ 102, 107 ], "name": "heart" }
{ "id": "C1267092", "pos": [ 139, 153 ], "name": "smooth muscles" }
0NA
Drug selection is based on efficacy in lowering BP and in reducing cardiovascular ( CV ) end points , including stroke , myocardial infarction , and heart failure .
{ "id": "C0007226", "pos": [ 67, 81 ], "name": "cardiovascular" }
{ "id": "C0038454", "pos": [ 112, 118 ], "name": "stroke" }
0NA
We conclude that chronic infection with C pneumoniae is associated with an increased risk of stroke and transient ischemic events .
{ "id": "C0151317", "pos": [ 17, 34 ], "name": "chronic infection" }
{ "id": "C0038454", "pos": [ 93, 99 ], "name": "stroke" }
0NA
In chronically ill patients olanzapine may have an advantage over other SGAs regarding longer time to treatment discontinuation and better drug adherence , but the drug is also associated with more metabolic side effects .
{ "id": "C0013227", "pos": [ 164, 168 ], "name": "drug" }
{ "id": "C0171023", "pos": [ 28, 38 ], "name": "olanzapine" }
0NA
This study represents the most comprehensive examination to date of the effects of detergents on peripheral nerve tissue morphology and protein composition .
{ "id": "C0031119", "pos": [ 97, 113 ], "name": "peripheral nerve" }
{ "id": "C0031809", "pos": [ 45, 56 ], "name": "examination" }
0NA
Thus , IL-2 secretion by tumors seems to be able to prevent immunosuppression by maintaining normal signal transduction in T cells , facilitating the generation of antitumor responses .
{ "id": "C0027651", "pos": [ 25, 31 ], "name": "tumors" }
{ "id": "C0021079", "pos": [ 60, 77 ], "name": "immunosuppression" }
0NA
This rise in IOP was blocked by DMPX pretreatment .
{ "id": "C0028778", "pos": [ 21, 28 ], "name": "blocked" }
{ "id": "C0578862", "pos": [ 13, 16 ], "name": "IOP" }
0NA
We report a rare case of concomitant pulmonary embolectomy and excision of a left atrial myxoma .
{ "id": "C0015252", "pos": [ 63, 71 ], "name": "excision" }
{ "id": "C0190587", "pos": [ 37, 58 ], "name": "pulmonary embolectomy" }
17method_of
Immunopotentiation abilities of sera from mice bearing fibrosarcoma or lymphoma for various periods of time were assayed using the plaque forming cell ( PFC ) technique .
{ "id": "C0229671", "pos": [ 32, 36 ], "name": "sera" }
{ "id": "C0011389", "pos": [ 131, 137 ], "name": "plaque" }
0NA
Several epidemiological , cellular , and molecular studies demonstrate the role of environmental chemicals with endocrine disrupting activities , typical of Westernized societies , in the pathogenesis of numerous diseases including cancer .
{ "id": "C0006826", "pos": [ 232, 238 ], "name": "cancer" }
{ "id": "C0012634", "pos": [ 213, 221 ], "name": "diseases" }
0NA
Indications for tissue expansion included scarcity of penile skin with urethral stenosis , urethrocutaneous fistula , chordee , and/or residual defect .
{ "id": "C0030851", "pos": [ 54, 60 ], "name": "penile" }
{ "id": "C0221182", "pos": [ 118, 125 ], "name": "chordee" }
11finding_site_of
The facial palsies were assessed with nerve conduction studies and , harvested ticks were identified .
{ "id": "C0015469", "pos": [ 4, 18 ], "name": "facial palsies" }
{ "id": "C0200125", "pos": [ 38, 62 ], "name": "nerve conduction studies" }
0NA
In Group A , the majority of dentin tubules were blocked by sclerotic rods .
{ "id": "C0028778", "pos": [ 49, 56 ], "name": "blocked" }
{ "id": "C0011429", "pos": [ 29, 35 ], "name": "dentin" }
0NA
The method is portable , accurate , sensitive , rapid , and exhibits good separation and anti-interference ability .
{ "id": "C0036679", "pos": [ 74, 84 ], "name": "separation" }
{ "id": "C0020517", "pos": [ 36, 45 ], "name": "sensitive" }
0NA
The primary outcome measure was change from baseline in worst pain intensity of the feet ( measured by participant self-report using an 11-point numerical pain rating scale ) after six weeks of treatment .
{ "id": "C0030193", "pos": [ 62, 66 ], "name": "pain" }
{ "id": "C0016504", "pos": [ 84, 88 ], "name": "feet" }
0NA
Besides HDL level , MGD is associated with another ocular surface disorder , namely pinguecula , as well as certain systemic diseases such as hypertension and diabetes mellitus .
{ "id": "C0011849", "pos": [ 159, 176 ], "name": "diabetes mellitus" }
{ "id": "C0020538", "pos": [ 142, 154 ], "name": "hypertension" }
0NA
Areas covered : This review is focused on the formulation and delivery of DNA to the lungs , using non-viral vectors .
{ "id": "C0024109", "pos": [ 85, 90 ], "name": "lungs" }
{ "id": "C0011209", "pos": [ 62, 70 ], "name": "delivery" }
0NA
Insulin treatment of 3T3 - 442A cells also results in a stimulation of RNA efflux from isolated , intact cell nuclei .
{ "id": "C1292856", "pos": [ 56, 67 ], "name": "stimulation" }
{ "id": "C0021641", "pos": [ 0, 7 ], "name": "Insulin" }
0NA
Thus , total replacement of the knee , possibly due to the performance of the arthroplasty under ischaemic conditions , appears to be more traumatic to the organism than total replacement of the hip .
{ "id": "C0022742", "pos": [ 32, 36 ], "name": "knee" }
{ "id": "C0003893", "pos": [ 78, 90 ], "name": "arthroplasty" }
0NA
Assessment of further studies is needed to explore the role of cytology and ancillary methods for detection of these tumors .
{ "id": "C0027651", "pos": [ 117, 123 ], "name": "tumors" }
{ "id": "C0031809", "pos": [ 0, 10 ], "name": "Assessment" }
0NA
A computed tomography ( CT ) revealed a calcified solid tumor in the upper portion of the right kidney .
{ "id": "C0040405", "pos": [ 2, 21 ], "name": "computed tomography" }
{ "id": "C0227613", "pos": [ 90, 102 ], "name": "right kidney" }
0NA
There is insufficient evidence for the use of anti-Alzheimer drugs , anti-Parkinson drugs , CNS stimulants and piracetam to promote stroke recovery .
{ "id": "C0002763", "pos": [ 92, 106 ], "name": "CNS stimulants" }
{ "id": "C0038454", "pos": [ 132, 138 ], "name": "stroke" }
0NA
In patients , occlusions of the middle cerebral artery are among the most common causes of ischaemic stroke .
{ "id": "C0028778", "pos": [ 14, 24 ], "name": "occlusions" }
{ "id": "C0948008", "pos": [ 91, 107 ], "name": "ischaemic stroke" }
0NA
These results suggest that soluble galectin-1 , but not galectin-3 , may exacerbate periodontal disease by enhancing the adhesion to and invasion of host cells by periodontal pathogenic bacteria .
{ "id": "C0001511", "pos": [ 121, 129 ], "name": "adhesion" }
{ "id": "C0031090", "pos": [ 84, 103 ], "name": "periodontal disease" }
0NA
We used cyclosporin A ( CA ) to treat 14 patients ( 25 eyes ) with Behçet 's disease characterized by severe retinal vasculitis and active intraocular inflammation .
{ "id": "C0021368", "pos": [ 151, 163 ], "name": "inflammation" }
{ "id": "C0152026", "pos": [ 109, 127 ], "name": "retinal vasculitis" }
3associated_morphology_of
The administration of phloroglucinol for 2 months in 5XFAD mice caused a reduction in the number of amyloid plaques and in the protein level of BACE1 , a major amyloid precursor protein cleavage enzyme , together with γ-secretase .
{ "id": "C0033684", "pos": [ 127, 134 ], "name": "protein" }
{ "id": "C0031566", "pos": [ 22, 36 ], "name": "phloroglucinol" }
0NA
There was almost no marked elevation of cytokines in the early stage of burn injury .
{ "id": "C0079189", "pos": [ 40, 49 ], "name": "cytokines" }
{ "id": "C0006434", "pos": [ 72, 83 ], "name": "burn injury" }
0NA
A case with systemic non-Hodgkin lymphoma involving the sella turcica and kidney is reported .
{ "id": "C0022646", "pos": [ 74, 80 ], "name": "kidney" }
{ "id": "C0036609", "pos": [ 56, 69 ], "name": "sella turcica" }
0NA
Osteoarthritis ( OA ) is a chronic , debilitating joint disease characterized by degenerative changes to the bones , cartilage , menisci , ligaments , and synovial tissue .
{ "id": "C0011164", "pos": [ 81, 93 ], "name": "degenerative" }
{ "id": "C0029408", "pos": [ 0, 14 ], "name": "Osteoarthritis" }
3associated_morphology_of
A prospective comparative case - control animal study conducted on 56 eyes of 28 healthy new born Sprague Dawley male albino rat .
{ "id": "C0015392", "pos": [ 70, 74 ], "name": "eyes" }
{ "id": "C0086582", "pos": [ 113, 117 ], "name": "male" }
0NA
Rapamycin ( which primarily inhibits mTORC1 ) , ATP-competitive , dual mTORC1/mTORC2 inhibitors and upstream regulators of the mTOR pathway are being developed to treat autoimmune , hyperproliferative and degenerative diseases .
{ "id": "C0443146", "pos": [ 169, 179 ], "name": "autoimmune" }
{ "id": "C0087111", "pos": [ 163, 168 ], "name": "treat" }
0NA
Fetal gas exchange was not negatively affected during the EXIT procedure as evidenced by normal blood gas values in the umbilical artery at the time of delivery .
{ "id": "C0184661", "pos": [ 63, 72 ], "name": "procedure" }
{ "id": "C0011209", "pos": [ 152, 160 ], "name": "delivery" }
0NA
In this MS study , neither APOE allele status nor promoter region heterogeneity at positions -219 G/T or + 113 C/G influenced the clinical disease severity , cognition , or cerebral atrophy .
{ "id": "C0003595", "pos": [ 27, 31 ], "name": "APOE" }
{ "id": "C0235946", "pos": [ 173, 189 ], "name": "cerebral atrophy" }
0NA
Bradykinin-induced VEGF secretion was dependent on the B2 bradykinin receptor , activation of protein kinase C , and generation of endogenous prostanoids .
{ "id": "C0429964", "pos": [ 38, 47 ], "name": "dependent" }
{ "id": "C0033554", "pos": [ 142, 153 ], "name": "prostanoids" }
0NA
She presented to the Emergency Department with severe chest pain following vomiting with hematemesis after a large meal .
{ "id": "C0205082", "pos": [ 47, 53 ], "name": "severe" }
{ "id": "C0018926", "pos": [ 89, 100 ], "name": "hematemesis" }
0NA
In this group of cells ryanodine only partially blocked the increase in [Ca2+]i induced by caffeine ; moreover , the change in [Ca2+]i that did occur was tightly coupled to the time course and magnitude of the cation current through these channels .
{ "id": "C0028778", "pos": [ 48, 55 ], "name": "blocked" }
{ "id": "C0006644", "pos": [ 91, 99 ], "name": "caffeine" }
0NA
Ten patients with chronic osteomyelitis of the femur or tibia shaft without bone instability were operated by intramedullary reaming .
{ "id": "C0015811", "pos": [ 47, 52 ], "name": "femur" }
{ "id": "C0588199", "pos": [ 56, 67 ], "name": "tibia shaft" }
0NA
This study indicates that temafloxacin would be suitable for the empirical treatment of lower respiratory tract infections , including high-risk groups such as the elderly and heavy smokers .
{ "id": "C0076075", "pos": [ 26, 38 ], "name": "temafloxacin" }
{ "id": "C0035243", "pos": [ 94, 122 ], "name": "respiratory tract infections" }
0NA
Seventeen percent of patients whose pulmonary symptoms responded to anti-reflux therapy would not have been recognized as having abnormal reflux if proximal pH monitoring had not been done .
{ "id": "C0205161", "pos": [ 129, 137 ], "name": "abnormal" }
{ "id": "C0150369", "pos": [ 160, 170 ], "name": "monitoring" }
0NA
MRI scans were also performed for the follow-up examinations .
{ "id": "C0024485", "pos": [ 0, 3 ], "name": "MRI" }
{ "id": "C0031809", "pos": [ 48, 60 ], "name": "examinations" }
0NA
Falls and fractures among the participants were followed over a 1-year period .
{ "id": "C0016658", "pos": [ 10, 19 ], "name": "fractures" }
{ "id": "C0000921", "pos": [ 0, 5 ], "name": "Falls" }
0NA
The (HSA)KIN17 RNA is ubiquitously expressed in all the tissues and organs examined , although muscle , heart and testis display the highest levels .
{ "id": "C0018787", "pos": [ 104, 109 ], "name": "heart" }
{ "id": "C0040300", "pos": [ 56, 63 ], "name": "tissues" }
0NA
During the first fall , he had a displaced fracture at the T11-T12 level without a spinal cord injury .
{ "id": "C0016658", "pos": [ 43, 51 ], "name": "fracture" }
{ "id": "C0037929", "pos": [ 83, 101 ], "name": "spinal cord injury" }
0NA
From 1982 to 1987 , 24 patients with recurrent carcinoma of the cervix underwent scalene lymph node biopsy prior to exploration for exenteration .
{ "id": "C0007874", "pos": [ 64, 70 ], "name": "cervix" }
{ "id": "C1280903", "pos": [ 116, 127 ], "name": "exploration" }
0NA
Finally , technologies related to the creation or characterization of enantiomerically pure drugs or their metabolites presumably will grow because of the increased number of compounds entering the drug development pipeline due to combinatorial chemistry .
{ "id": "C0013227", "pos": [ 92, 97 ], "name": "drugs" }
{ "id": "C0441513", "pos": [ 38, 46 ], "name": "creation" }
0NA
They had undergone cataract removal by phacoemulsification with intraocular lens implantation from January 2002 to December 2006 at the Department of Ophthalmology , Rijeka University Hospital , Croatia .
{ "id": "C0021107", "pos": [ 81, 93 ], "name": "implantation" }
{ "id": "C0086543", "pos": [ 19, 27 ], "name": "cataract" }
0NA
Most patients diagnosed with ovarian cancer will ultimately die from their disease .
{ "id": "C0919267", "pos": [ 29, 43 ], "name": "ovarian cancer" }
{ "id": "C0012634", "pos": [ 75, 82 ], "name": "disease" }
0NA
Necrotic trophoblastic debris that is deported in the maternal blood is one possible placental trigger for preeclampsia .
{ "id": "C0027540", "pos": [ 0, 8 ], "name": "Necrotic" }
{ "id": "C0032914", "pos": [ 107, 119 ], "name": "preeclampsia" }
0NA
Malignant mesotheliomas of the tunica vaginalis are extremely rare tumors , especially in young patients .
{ "id": "C0027651", "pos": [ 67, 73 ], "name": "tumors" }
{ "id": "C0228014", "pos": [ 31, 47 ], "name": "tunica vaginalis" }
0NA
Explosion was the most frequent cause of injury in all cases and caused damage to several organ systems .
{ "id": "C0010957", "pos": [ 72, 78 ], "name": "damage" }
{ "id": "C0005700", "pos": [ 0, 9 ], "name": "Explosion" }
3associated_morphology_of
In the tests for digoxin , cortisol , alpha 1-fetoprotein and acid prostate phosphatase , the use of plasma as sample material resulted in varying degrees of interference .
{ "id": "C0012265", "pos": [ 17, 24 ], "name": "digoxin" }
{ "id": "C0020268", "pos": [ 27, 35 ], "name": "cortisol" }
0NA