text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Studies of oral ecology have led to an appreciation of the complexity of the interactions that oral micro-organisms have with the host in both health and disease . | {
"id": "C0226896",
"pos": [
95,
99
],
"name": "oral"
} | {
"id": "C0012634",
"pos": [
154,
161
],
"name": "disease"
} | 0NA |
The dependent variable for this analysis was the dichotomous outcome : healed versus disease . | {
"id": "C0429964",
"pos": [
4,
13
],
"name": "dependent"
} | {
"id": "C0012634",
"pos": [
85,
92
],
"name": "disease"
} | 0NA |
All patients had active disease at inclusion and were followed for 6 weeks of anti-TNF-α antibody or prednisolone treatment . | {
"id": "C0003241",
"pos": [
89,
97
],
"name": "antibody"
} | {
"id": "C0032950",
"pos": [
101,
113
],
"name": "prednisolone"
} | 0NA |
Upon liver injury , HSCs differentiate into myofibroblasts and participate in progression of fibrosis and cirrhosis . | {
"id": "C0016059",
"pos": [
93,
101
],
"name": "fibrosis"
} | {
"id": "C0023890",
"pos": [
106,
115
],
"name": "cirrhosis"
} | 0NA |
These DNA damages , caused by PAC drug , were prevented by pretreatment of cells with vitamin B12 . | {
"id": "C0013227",
"pos": [
34,
38
],
"name": "drug"
} | {
"id": "C0042845",
"pos": [
86,
97
],
"name": "vitamin B12"
} | 0NA |
Blocks of the tumours and of the surrounding mucosa were immunostained with the monoclonal antibody DO-7 . | {
"id": "C0028778",
"pos": [
0,
6
],
"name": "Blocks"
} | {
"id": "C0026724",
"pos": [
45,
51
],
"name": "mucosa"
} | 0NA |
Light and electron microscopy demonstrated that the superficial fibrin and inflammatory cell layers and intermediate blood capillary layer of the ulcer bed , which were primarily granulation tissue , did not contain lymphatics . | {
"id": "C0041582",
"pos": [
146,
151
],
"name": "ulcer"
} | {
"id": "C0026019",
"pos": [
10,
29
],
"name": "electron microscopy"
} | 0NA |
Taken together , these results suggest that the molecular properties of BlDnaK have been significantly changed upon the individual replacement of selected phenylalanine residues by tryptophan . | {
"id": "C0035139",
"pos": [
131,
142
],
"name": "replacement"
} | {
"id": "C0041249",
"pos": [
181,
191
],
"name": "tryptophan"
} | 0NA |
Contraindications to triptan use , adverse effects of NSAIDs , and unwanted reactions to some antiemetics reduce the list of drugs available for the treatment of migraine attacks in elderly patients . | {
"id": "C0013227",
"pos": [
125,
130
],
"name": "drugs"
} | {
"id": "C0162754",
"pos": [
21,
28
],
"name": "triptan"
} | 0NA |
The lung allocation score ( LAS ) was developed in an effort to facilitate lung transplantation to more urgent and ill patients , to decrease wait time , and to change the allocation process to a more merit-based system . | {
"id": "C0231218",
"pos": [
115,
118
],
"name": "ill"
} | {
"id": "C0024128",
"pos": [
75,
95
],
"name": "lung transplantation"
} | 0NA |
Compared with individuals without skin lesions , pronounced systemic T-helper ( Th ) 2-type responses were found with a trend of increasing intensity in the order of depigmentation , papular dermatitis , atrophy and lichenified dermatitis . | {
"id": "C0333641",
"pos": [
204,
211
],
"name": "atrophy"
} | {
"id": "C0162835",
"pos": [
166,
180
],
"name": "depigmentation"
} | 0NA |
Therefore , in clinical use appropriate medications should be selected based on the data obtained from antimicrobial susceptibility tests . | {
"id": "C0013227",
"pos": [
40,
51
],
"name": "medications"
} | {
"id": "C0201179",
"pos": [
103,
137
],
"name": "antimicrobial susceptibility tests"
} | 0NA |
Trephination of the cranial vault is the oldest known surgical procedure and has often been reported in the literature . | {
"id": "C0040836",
"pos": [
0,
12
],
"name": "Trephination"
} | {
"id": "C0543467",
"pos": [
54,
72
],
"name": "surgical procedure"
} | 0NA |
Hypertension incidence may contribute to geographic and racial differences in cardiovascular disease mortality , including stroke . | {
"id": "C0020538",
"pos": [
0,
12
],
"name": "Hypertension"
} | {
"id": "C0038454",
"pos": [
123,
129
],
"name": "stroke"
} | 0NA |
Transverse arch ratios on MRI were compared with those on preoperative cineangiography and the pressure gradient between the patient 's right and left arm . | {
"id": "C0024485",
"pos": [
26,
29
],
"name": "MRI"
} | {
"id": "C0230347",
"pos": [
146,
154
],
"name": "left arm"
} | 0NA |
Uptake of glycine was also increased after addition of glucose ( hexose ) in the dark . | {
"id": "C0017725",
"pos": [
55,
62
],
"name": "glucose"
} | {
"id": "C0017890",
"pos": [
10,
17
],
"name": "glycine"
} | 0NA |
In animals in which the LH surge was disrupted by the surgical procedure but had a normal proestrous PRL surge , neither progesterone nor collagenolytic activity increased in the perfusate fluid . | {
"id": "C0033371",
"pos": [
101,
104
],
"name": "PRL"
} | {
"id": "C0543467",
"pos": [
54,
72
],
"name": "surgical procedure"
} | 0NA |
People go to traditional healers not only to cure their diseases but also to obtain advice about their personal problems . | {
"id": "C0150600",
"pos": [
84,
90
],
"name": "advice"
} | {
"id": "C0012634",
"pos": [
56,
64
],
"name": "diseases"
} | 0NA |
Also the effective dose equivalent to the body of the patient , exclusive of the thyroid , is given . | {
"id": "C0040132",
"pos": [
81,
88
],
"name": "thyroid"
} | {
"id": "C0227230",
"pos": [
42,
46
],
"name": "body"
} | 0NA |
No material change in function was observed in the patients whose condition was not improved by the operation . | {
"id": "C0012634",
"pos": [
66,
75
],
"name": "condition"
} | {
"id": "C0543467",
"pos": [
100,
109
],
"name": "operation"
} | 0NA |
The protective effects of berberine and phentolamine against anoxia and reoxygenation damage in isolated rat hearts have been investigated . | {
"id": "C0010957",
"pos": [
86,
92
],
"name": "damage"
} | {
"id": "C0018787",
"pos": [
109,
115
],
"name": "hearts"
} | 0NA |
At 7,4 months both sub-groups with fractures had a lower level of function compared to patients with bone bruises , activity score and symptoms showed poorer results in the group without intraarticular lesion ( p = 0,01 for all scores ) . | {
"id": "C0016658",
"pos": [
35,
44
],
"name": "fractures"
} | {
"id": "C0559359",
"pos": [
101,
113
],
"name": "bone bruises"
} | 0NA |
The current study aimed to compare the effects of treatment ( 2 months ) with thiazolidinediones ( TZDs ) and placebo on glucose and fat metabolism in patients with type 2 diabetes ( T2DM ) in a crossover design . | {
"id": "C0017725",
"pos": [
121,
128
],
"name": "glucose"
} | {
"id": "C1257987",
"pos": [
78,
96
],
"name": "thiazolidinediones"
} | 0NA |
This analysis provides a better understanding of the reproductive consequences for carriers of balanced CCRs and should be useful in prenatal diagnosis and genetic counseling . | {
"id": "C0007294",
"pos": [
83,
91
],
"name": "carriers"
} | {
"id": "C0017382",
"pos": [
156,
174
],
"name": "genetic counseling"
} | 0NA |
( 2 ) The reduction of IGP induced by electrical stimulation of ARC was not affected by intracerebroventricular injection of naloxone . | {
"id": "C0027358",
"pos": [
125,
133
],
"name": "naloxone"
} | {
"id": "C0021485",
"pos": [
112,
121
],
"name": "injection"
} | 0NA |
Newly discovered elevation of PHB , PHB2 , and SEPT9 in GST-P(+ ) foci and tumors , imply that they might play important role in the onset of liver cancer and be of potential values in the studies of hepatocarcinogenesis . | {
"id": "C0027651",
"pos": [
75,
81
],
"name": "tumors"
} | {
"id": "C0439775",
"pos": [
17,
26
],
"name": "elevation"
} | 0NA |
Adhesion was also inhibited by preincubation with 100 U/ml heparin . | {
"id": "C0001511",
"pos": [
0,
8
],
"name": "Adhesion"
} | {
"id": "C0019134",
"pos": [
59,
66
],
"name": "heparin"
} | 0NA |
NGF gene expression in one of these tissues , the iris , was shown to be induced by denervation . | {
"id": "C0022077",
"pos": [
50,
54
],
"name": "iris"
} | {
"id": "C0040300",
"pos": [
36,
43
],
"name": "tissues"
} | 0NA |
A number of factors should determine the need for intervention including pain , mechanical symptoms , abductor weakness , component type , component position , and ion levels as well as MRI findings . | {
"id": "C0024485",
"pos": [
186,
189
],
"name": "MRI"
} | {
"id": "C0184661",
"pos": [
50,
62
],
"name": "intervention"
} | 0NA |
Group II ( n = 7 ): A loading dose of 1 μg/kg DEX was administered over 10 minutes followed by an infusion of 0.5 μg/kg/hr for one hour via the peripheral venous catheter . | {
"id": "C0011816",
"pos": [
46,
49
],
"name": "DEX"
} | {
"id": "C0745442",
"pos": [
155,
170
],
"name": "venous catheter"
} | 0NA |
Only 34 patients ( 25 % of those with positive urine cultures ) met the criteria for a symptomatic urinary tract infection ; 67 ( 49 % ) had asymptomatic bacteriuria and 36 ( 26 % ) had infection at a nonurinary site . | {
"id": "C1446409",
"pos": [
38,
46
],
"name": "positive"
} | {
"id": "C0004659",
"pos": [
154,
165
],
"name": "bacteriuria"
} | 14interpretation_of |
By random allocation , each defect was filled with PPart or PPutty , and the flaps were closed with sutures . | {
"id": "C0038925",
"pos": [
77,
82
],
"name": "flaps"
} | {
"id": "C0038969",
"pos": [
100,
107
],
"name": "sutures"
} | 0NA |
The Draize rabbit eye test has been used for 60 years in attempts to predict human ocular irritancy based on topical instillation of the potential irritant and subjective scoring of ocular inflammation by direct visualization of the rabbit eye . | {
"id": "C0015392",
"pos": [
240,
243
],
"name": "eye"
} | {
"id": "C0184959",
"pos": [
117,
129
],
"name": "instillation"
} | 0NA |
These findings are not in accord with the hypothesis that hyperplastic polyp is a simple hyperplasia of the mucosal epithelium and suggest a disorder in cellular differentiation , particularly for the larger polyps . | {
"id": "C0032584",
"pos": [
208,
214
],
"name": "polyps"
} | {
"id": "C0012634",
"pos": [
141,
149
],
"name": "disorder"
} | 0NA |
In response to liquid infusion , the ileum segments generated propulsive complexes rapidly propagating along the entire segment in the aboral direction , resulting in emptying of the luminal contents . | {
"id": "C0301571",
"pos": [
15,
21
],
"name": "liquid"
} | {
"id": "C0574032",
"pos": [
22,
30
],
"name": "infusion"
} | 0NA |
Cytogenetic analyses of four squamous cell carcinomas ( SCC ) of the esophagus showed complex numerical and structural abnormalities . | {
"id": "C0014876",
"pos": [
69,
78
],
"name": "esophagus"
} | {
"id": "C0007137",
"pos": [
29,
53
],
"name": "squamous cell carcinomas"
} | 0NA |
Uterine , mesenteric , and renal arteries from late-pregnant and virgin mice were isolated and studied in a pressure-arteriograph system ( n = 23 ) . | {
"id": "C0042149",
"pos": [
0,
7
],
"name": "Uterine"
} | {
"id": "C0035065",
"pos": [
27,
41
],
"name": "renal arteries"
} | 0NA |
Interleukin 6-knockout mice given ethanol and burn injury also had reduced intestinal damage ; however , no changes in bacterial translocation or tight junction protein localization were observed as compared with similarly treated wild-type mice . | {
"id": "C0021853",
"pos": [
75,
85
],
"name": "intestinal"
} | {
"id": "C0006434",
"pos": [
46,
57
],
"name": "burn injury"
} | 0NA |
We concluded that intervention for managing residual CV risk during statin therapy should be implemented . | {
"id": "C1278454",
"pos": [
68,
82
],
"name": "statin therapy"
} | {
"id": "C0184661",
"pos": [
18,
30
],
"name": "intervention"
} | 0NA |
C-ANCA antigen specificity may depend on the pathogenesis of the underlying disease , potentially elicited by a cross-reaction of an antibody to foreign and self target antigen sequence homology or alternatively elicited by antigenic epitope spread . | {
"id": "C0003241",
"pos": [
133,
141
],
"name": "antibody"
} | {
"id": "C0012634",
"pos": [
76,
83
],
"name": "disease"
} | 0NA |
Glaucoma is the major ophthalmic public health issue and a leading basis of blindness . | {
"id": "C0015392",
"pos": [
22,
32
],
"name": "ophthalmic"
} | {
"id": "C0017601",
"pos": [
0,
8
],
"name": "Glaucoma"
} | 11finding_site_of |
After ERCP and stent deployment , patients were followed for 72 h for symptoms and signs of cholangitis . | {
"id": "C0038257",
"pos": [
15,
20
],
"name": "stent"
} | {
"id": "C0008310",
"pos": [
6,
10
],
"name": "ERCP"
} | 0NA |
Coronary patients displayed significantly greater Type A attributes than control subjects and tended to show greater blood pressure elevations than controls during the interview . | {
"id": "C0018787",
"pos": [
0,
8
],
"name": "Coronary"
} | {
"id": "C0005823",
"pos": [
117,
131
],
"name": "blood pressure"
} | 0NA |
The results suggest that bradykinin stimulates osteoclast-mediated bone resorption by a process that is dependent on endogenous prostaglandin production . | {
"id": "C0429964",
"pos": [
104,
113
],
"name": "dependent"
} | {
"id": "C0033554",
"pos": [
128,
141
],
"name": "prostaglandin"
} | 0NA |
Taken together , we conclude that PGC-1 coactivators are necessary for the oxidative and mitochondrial programs of skeletal muscle but are dispensable for fundamental fiber type determination and insulin sensitivity . | {
"id": "C0242692",
"pos": [
115,
130
],
"name": "skeletal muscle"
} | {
"id": "C0020517",
"pos": [
204,
215
],
"name": "sensitivity"
} | 0NA |
Analyses of human colorectal carcinoma tissues and liver metastases revealed a polydisperse WGA-reactive high-molecular-weight component similar to that seen in tumors growing in nude mice . | {
"id": "C0027651",
"pos": [
161,
167
],
"name": "tumors"
} | {
"id": "C0040300",
"pos": [
39,
46
],
"name": "tissues"
} | 0NA |
Meanwhile , high miR-33b expressions were found majorly in OS tumors with low LDHA mRNA levels ( 82.4 % ) . | {
"id": "C0027651",
"pos": [
62,
68
],
"name": "tumors"
} | {
"id": "C0185117",
"pos": [
25,
36
],
"name": "expressions"
} | 0NA |
Our findings suggest a combined role for perforin mutation and abnormal CD45 splicing as significant contributory factors in the pathogenesis of HLH . | {
"id": "C0205161",
"pos": [
63,
71
],
"name": "abnormal"
} | {
"id": "C0024291",
"pos": [
145,
148
],
"name": "HLH"
} | 0NA |
This report expands the ophthalmological phenotype of the late-onset neurodegenerative form of CHS to include optic neuropathy with progressive vision loss , even in the absence of ocular albinism , and abnormal prominence of the interdigitation zone between cone outer segment tips and apical processes of retinal pigment epithelium cells on macular OCT . | {
"id": "C0205161",
"pos": [
203,
211
],
"name": "abnormal"
} | {
"id": "C0007965",
"pos": [
95,
98
],
"name": "CHS"
} | 14interpretation_of |
Their real importance lies in their potential to result in exsanguination , which usually follows an unrelated treatment , such as tooth extraction , surgical intervention , puncture wound or blunt injury in involved areas , with the dentist unaware of the existence of the AVM . | {
"id": "C0033119",
"pos": [
174,
188
],
"name": "puncture wound"
} | {
"id": "C0040440",
"pos": [
131,
147
],
"name": "tooth extraction"
} | 0NA |
Mitilane , containing alpha-1,4;1,6-D-glucane and some amount of protein is more effective in stimulation of membrane receptors expression than translam -- beta-1,3;1,6-D-glucane . | {
"id": "C1292856",
"pos": [
94,
105
],
"name": "stimulation"
} | {
"id": "C0033684",
"pos": [
65,
72
],
"name": "protein"
} | 0NA |
Calcifying pseudoneoplasms of the neuraxis ( CAPNON ) are rare and typically benign lesions that can occur anywhere within the central nervous system . | {
"id": "C0221198",
"pos": [
84,
91
],
"name": "lesions"
} | {
"id": "C3714787",
"pos": [
34,
42
],
"name": "neuraxis"
} | 0NA |
Periodontal status was evaluated by probing depth , bleeding on probing , and gingival index . | {
"id": "C0019080",
"pos": [
52,
60
],
"name": "bleeding"
} | {
"id": "C0419358",
"pos": [
64,
71
],
"name": "probing"
} | 0NA |
E2 and E3 were also of equal potency with respect to the stimulation of enhanced glucose utilization , water imbibition , the incorporation of 14C-glucose into lipid , protein and RNA 3 hours following an injection of the hormone . | {
"id": "C1292856",
"pos": [
57,
68
],
"name": "stimulation"
} | {
"id": "C0033684",
"pos": [
168,
175
],
"name": "protein"
} | 0NA |
The main effects observed were tiny regions of extravasated red blood cells scattered around the sonicated locations , indicating affected capillaries . | {
"id": "C0006901",
"pos": [
139,
150
],
"name": "capillaries"
} | {
"id": "C0014772",
"pos": [
60,
75
],
"name": "red blood cells"
} | 0NA |
This finding , coupled with observations that LPS evoked ∼30-fold greater renal Hpx mRNA increases than any other AKI model , suggests that inflammation , not heme exposure , activates the renal Hpx gene . | {
"id": "C0022646",
"pos": [
74,
79
],
"name": "renal"
} | {
"id": "C0022660",
"pos": [
114,
117
],
"name": "AKI"
} | 11finding_site_of |
The DRPT was positive , if intraocular pressure increased by ≥8 mm Hg after 1.5 hours of dark adaptation . | {
"id": "C1446409",
"pos": [
13,
21
],
"name": "positive"
} | {
"id": "C0021888",
"pos": [
27,
47
],
"name": "intraocular pressure"
} | 0NA |
Thirteen received both drugs concurrently , and 17 received warfarin alone and the combination sequentially . | {
"id": "C0013227",
"pos": [
23,
28
],
"name": "drugs"
} | {
"id": "C0043031",
"pos": [
60,
68
],
"name": "warfarin"
} | 0NA |
They were subjected to assessment of semen parameters , seminal levels of testosterone ( T ) , androstenedione ( A ) , 5α-androstane-3 α,17 β-diol ( 3 α-diol ) , oestradiol ( E2 ) , 17-hydroxyprogesterone ( 17-OHP ) and progesterone ( P ) . | {
"id": "C0045010",
"pos": [
182,
204
],
"name": "17-hydroxyprogesterone"
} | {
"id": "C0202075",
"pos": [
207,
213
],
"name": "17-OHP"
} | 6component_of |
The eye and the skin are protected by a multi-layered epithelial barrier that provides the first line of defence against invading pathogens and environmental stresses such as damaging solar ultraviolet radiation . | {
"id": "C0015392",
"pos": [
4,
7
],
"name": "eye"
} | {
"id": "C0444099",
"pos": [
16,
20
],
"name": "skin"
} | 0NA |
Two deaths occurred during the first postoperative month , due to acute respiratory distress syndrome and multiorgan failure , both in patients with adult polycystic disease who were in poor nutritional condition due to a late indication for CLKT . | {
"id": "C0011065",
"pos": [
4,
10
],
"name": "deaths"
} | {
"id": "C0035222",
"pos": [
66,
101
],
"name": "acute respiratory distress syndrome"
} | 0NA |
About 30 % of PACG eyes with a patent laser peripheral iridotomy were found to have plateau iris on UBM , highlighting the importance of non-pupil block mechanisms in Asian individuals . | {
"id": "C0015392",
"pos": [
19,
23
],
"name": "eyes"
} | {
"id": "C0339575",
"pos": [
84,
96
],
"name": "plateau iris"
} | 0NA |
Rosetting of erythrocytes infected with Plasmodium falciparum is frequently observed in children with severe malaria . | {
"id": "C0024530",
"pos": [
109,
116
],
"name": "malaria"
} | {
"id": "C0014772",
"pos": [
13,
25
],
"name": "erythrocytes"
} | 0NA |
The aim of the study was to assess the effect of 1-year captopril therapy initiated 1 - 4 days ( mean : 21 - 24 h ) after beginning of AMI on exercise performance and myocardial ischemia during cycle ergometer test . | {
"id": "C0027051",
"pos": [
135,
138
],
"name": "AMI"
} | {
"id": "C0010054",
"pos": [
167,
186
],
"name": "myocardial ischemia"
} | 0NA |
At 2 weeks after transplantation , motor function test and cerebral edema assay were performed and followed by pathological examination including hematoxylin and eosin and immunohistochemistry staining to observe the neuron injury and synapsin I and growth associated protein-43 ( GAP-43 ) expression . | {
"id": "C3263722",
"pos": [
224,
230
],
"name": "injury"
} | {
"id": "C0040732",
"pos": [
17,
32
],
"name": "transplantation"
} | 0NA |
A three-dimensional model of the upper limb was used to calculate the muscle and joint-contact forces at the shoulder for abduction in the scapular plane . | {
"id": "C0037004",
"pos": [
109,
117
],
"name": "shoulder"
} | {
"id": "C0026845",
"pos": [
70,
76
],
"name": "muscle"
} | 0NA |
These growth patterns , which were not predictable from clonogenic assays on the marrow cells prior to LTBMC , or from the morphology of the bone marrow , may reflect the stage of evolution of the disease . | {
"id": "C0005953",
"pos": [
141,
152
],
"name": "bone marrow"
} | {
"id": "C0012634",
"pos": [
197,
204
],
"name": "disease"
} | 0NA |
Of 961 surgical procedures , 767 ( 80 % ) received one or several antibiotics ; the surgical site infection rate was 4 % . | {
"id": "C0038941",
"pos": [
84,
107
],
"name": "surgical site infection"
} | {
"id": "C0543467",
"pos": [
7,
26
],
"name": "surgical procedures"
} | 18occurs_after |
These results are consistent with the view that HNMT is well expressed in the human liver and renal cortex and that it varies among subjects . | {
"id": "C0023884",
"pos": [
84,
89
],
"name": "liver"
} | {
"id": "C0022655",
"pos": [
94,
106
],
"name": "renal cortex"
} | 0NA |
The HMD system offers simultaneous , high-quality magnified imagery in front of the eyes , regardless of head position , to those participating in the endoscopic procedures . | {
"id": "C0015392",
"pos": [
84,
88
],
"name": "eyes"
} | {
"id": "C0282493",
"pos": [
151,
172
],
"name": "endoscopic procedures"
} | 0NA |
Immunization of susceptible C57BL/6 mice with CpG ODN deviates the immune response from a Th2- toward a Th1-type response following infection with C. neoformans . | {
"id": "C0020971",
"pos": [
0,
12
],
"name": "Immunization"
} | {
"id": "C0009450",
"pos": [
132,
141
],
"name": "infection"
} | 0NA |
It would seem that the risk of inducing acute CAG is far outweighed by the potential benefit of examining the eye through a dilated pupil . | {
"id": "C0015392",
"pos": [
110,
113
],
"name": "eye"
} | {
"id": "C0026961",
"pos": [
124,
137
],
"name": "dilated pupil"
} | 0NA |
Consideration is essentially given to industrial carcinogens , tryptophan metabolites , phenacetin , nicotine , coffee , artificial sweeteners , and chronic irritations of the bladder urothelium . | {
"id": "C0005682",
"pos": [
176,
183
],
"name": "bladder"
} | {
"id": "C0227598",
"pos": [
184,
194
],
"name": "urothelium"
} | 0NA |
It is likely that this was caused by the apamin in the sting which has an effect on the upper limb , at the spinal cord and on the peripheral nerves . | {
"id": "C1140618",
"pos": [
88,
98
],
"name": "upper limb"
} | {
"id": "C0037925",
"pos": [
108,
119
],
"name": "spinal cord"
} | 0NA |
Prostate cancer ( PCa ) , akin to other cancers , is characterized by high telomerase activity . | {
"id": "C0006826",
"pos": [
40,
47
],
"name": "cancers"
} | {
"id": "C0376358",
"pos": [
0,
15
],
"name": "Prostate cancer"
} | 0NA |
Because of the specificity of COX-2 expression , COX-2 inhibitors have the potential to reduce the risk of gastrointestinal bleeding experienced with the use of classic NSAIDs . | {
"id": "C0003211",
"pos": [
169,
175
],
"name": "NSAIDs"
} | {
"id": "C0017181",
"pos": [
107,
132
],
"name": "gastrointestinal bleeding"
} | 0NA |
Methaemoglobin reductase activity was studied in pig , human and cattle erythrocytes incubated in a medium containing glucose or inosine as NADH generator . | {
"id": "C0021528",
"pos": [
129,
136
],
"name": "inosine"
} | {
"id": "C0014772",
"pos": [
72,
84
],
"name": "erythrocytes"
} | 0NA |
As temperature is increased sensitivity is enhanced , particularly at low and intermediate frequencies . | {
"id": "C0020517",
"pos": [
28,
39
],
"name": "sensitivity"
} | {
"id": "C0005903",
"pos": [
3,
14
],
"name": "temperature"
} | 0NA |
Acetabular fractures managed either conservatively or operatively by fixation tend to present later with secondary joint changes that require THR . | {
"id": "C0185023",
"pos": [
69,
77
],
"name": "fixation"
} | {
"id": "C0347804",
"pos": [
0,
20
],
"name": "Acetabular fractures"
} | 0NA |
Radiographs of the vertebral column , hand , and wrist of 3 adults with kyphosis confirmed the diagnosis of skeletal fluorosis . | {
"id": "C0043262",
"pos": [
49,
54
],
"name": "wrist"
} | {
"id": "C1306645",
"pos": [
0,
11
],
"name": "Radiographs"
} | 0NA |
Two distinct cardiovascular patterns of mean arterial pressure ( MAP ) and heart rate ( HR ) were observed . | {
"id": "C0007226",
"pos": [
13,
27
],
"name": "cardiovascular"
} | {
"id": "C0018810",
"pos": [
75,
85
],
"name": "heart rate"
} | 0NA |
The distance from sternum , mid-clavicular line , and lateral pectoralis minor , as well as nerve diameter , was measured . | {
"id": "C0027740",
"pos": [
92,
97
],
"name": "nerve"
} | {
"id": "C0038293",
"pos": [
18,
25
],
"name": "sternum"
} | 0NA |
This indicates that telomerase-induced telomere length manipulations may have utility for tissue engineering and for dissecting the molecular mechanisms underlying genetic diseases including cancer . | {
"id": "C0006826",
"pos": [
191,
197
],
"name": "cancer"
} | {
"id": "C0019247",
"pos": [
164,
180
],
"name": "genetic diseases"
} | 0NA |
Therefore , routine adrenalectomy should not be recommended if the preoperative radiological examinations are normal . | {
"id": "C0031809",
"pos": [
93,
105
],
"name": "examinations"
} | {
"id": "C0001632",
"pos": [
20,
33
],
"name": "adrenalectomy"
} | 0NA |
Official projections of the cholera epidemic in Haiti have not incorporated existing disease trends or patterns of transmission , and proposed interventions have been debated without comparative estimates of their effect . | {
"id": "C0012634",
"pos": [
85,
92
],
"name": "disease"
} | {
"id": "C0008354",
"pos": [
28,
35
],
"name": "cholera"
} | 0NA |
The question of whether ampicillin and sulbactam are able to penetrate sufficiently into costal cartilage tissue was investigated in 21 children undergoing surgery for funnel chest malformations . | {
"id": "C0002680",
"pos": [
24,
34
],
"name": "ampicillin"
} | {
"id": "C0038665",
"pos": [
39,
48
],
"name": "sulbactam"
} | 0NA |
Histology revealed deposition of pigmented brown cells in response to CuO NP , located predominantly along the mantle and gill margin but also lining digestive tubules and some of the sinuses and distributed throughout the connective tissue and in the adductor muscle . | {
"id": "C0030471",
"pos": [
184,
191
],
"name": "sinuses"
} | {
"id": "C0009780",
"pos": [
223,
240
],
"name": "connective tissue"
} | 0NA |
We report a case of homozygous arginase deficiency belatedly diagnosed at the age of 18 years , when treatment with sodium valproate ( VPA ) was instituted . | {
"id": "C0037567",
"pos": [
116,
132
],
"name": "sodium valproate"
} | {
"id": "C0042291",
"pos": [
135,
138
],
"name": "VPA"
} | 16is_modification_of |
We experimentally demonstrate that joint statistical distributions of the characteristic parameters of RBCs can be obtained by our algorithm and efficiently used as a feature pattern to discriminate between RBC populations that differ in shape and hemoglobin content . | {
"id": "C0019046",
"pos": [
248,
258
],
"name": "hemoglobin"
} | {
"id": "C0014772",
"pos": [
207,
210
],
"name": "RBC"
} | 0NA |
Pre-treatment with perindopril did not alter the changes in UFR ( P=0.63 ) , UcGMP ( P=0.46 ) or UAER ( P=0.99 ) to infusion of ANP , compared with the placebo/ANP arm . | {
"id": "C0027481",
"pos": [
128,
131
],
"name": "ANP"
} | {
"id": "C0574032",
"pos": [
116,
124
],
"name": "infusion"
} | 0NA |
In nonreproductive peripheral tissues ( liver and kidney ) , E2 delayed the phase and increased the amplitude of Per1 mRNA expression . | {
"id": "C0022646",
"pos": [
50,
56
],
"name": "kidney"
} | {
"id": "C0023884",
"pos": [
40,
45
],
"name": "liver"
} | 0NA |
Recent recommendations suggested a change in drug therapy for asthma , away from theophylline and toward patient-administered MDIs containing beta 2-agonists or corticosteroids . | {
"id": "C0013216",
"pos": [
45,
57
],
"name": "drug therapy"
} | {
"id": "C0001617",
"pos": [
161,
176
],
"name": "corticosteroids"
} | 0NA |
While 28 % of patients reported cleaning their dentures at least daily , 6 % presented with denture stomatitis ( DS ) . | {
"id": "C0011394",
"pos": [
47,
55
],
"name": "dentures"
} | {
"id": "C0038364",
"pos": [
92,
110
],
"name": "denture stomatitis"
} | 4causative_agent_of |
Generally inguinal and axillary lymph nodes are larger than cervical ones . | {
"id": "C0027530",
"pos": [
60,
68
],
"name": "cervical"
} | {
"id": "C0729594",
"pos": [
23,
43
],
"name": "axillary lymph nodes"
} | 0NA |
As a consequence , some cancers are not detected by mammography screening . | {
"id": "C0006826",
"pos": [
24,
31
],
"name": "cancers"
} | {
"id": "C0199230",
"pos": [
64,
73
],
"name": "screening"
} | 12focus_of |
Animals are not always treated at FMD inspections points , but satisfied respondents were more likely to seek veterinary assistance ( P=0.001 ) . | {
"id": "C0199219",
"pos": [
38,
49
],
"name": "inspections"
} | {
"id": "C0016052",
"pos": [
34,
37
],
"name": "FMD"
} | 0NA |
Thus , the mutant may be used to effectively prevent (-)-cocaine from entering brain and producing physiological effects in the enzyme-based treatment of cocaine abuse . | {
"id": "C0009170",
"pos": [
53,
64
],
"name": "(-)-cocaine"
} | {
"id": "C0009171",
"pos": [
154,
167
],
"name": "cocaine abuse"
} | 4causative_agent_of |
One-hundred and four eyes of 104 glaucoma patients , defined by the appearance of the optic nerve head , were evaluated . | {
"id": "C0015392",
"pos": [
21,
25
],
"name": "eyes"
} | {
"id": "C0017601",
"pos": [
33,
41
],
"name": "glaucoma"
} | 11finding_site_of |
A 74-year-old female exhibited parkinsonism and later , dementia , myoclonus as well as visual hallucinations , lacking periodic synchronous discharges in the electroencephalogram . | {
"id": "C0242422",
"pos": [
31,
43
],
"name": "parkinsonism"
} | {
"id": "C0013819",
"pos": [
159,
179
],
"name": "electroencephalogram"
} | 0NA |
The effects of leg movement on five leg muscles along with hip , knee , and ankle joint torques were established simultaneously with the modulation pattern of the flexion reflex during hip oscillations . | {
"id": "C0023216",
"pos": [
15,
18
],
"name": "leg"
} | {
"id": "C0026649",
"pos": [
19,
27
],
"name": "movement"
} | 0NA |
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