text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
To assess the role of opioid-mediated stress-induced antinociception , mice were also tested for nociceptive sensitivity after injection of naloxone ( 10 mg/kg ) or saline . | {
"id": "C0027358",
"pos": [
140,
148
],
"name": "naloxone"
} | {
"id": "C0021485",
"pos": [
127,
136
],
"name": "injection"
} | 0NA |
Many types of cells experience repetitive loading which may cause failure or damage requiring repair . | {
"id": "C0010957",
"pos": [
77,
83
],
"name": "damage"
} | {
"id": "C0043240",
"pos": [
94,
100
],
"name": "repair"
} | 0NA |
Epilepsy is a severe neurological disorder characterized by altered electrical activity in the brain . | {
"id": "C0006104",
"pos": [
95,
100
],
"name": "brain"
} | {
"id": "C0014544",
"pos": [
0,
8
],
"name": "Epilepsy"
} | 11finding_site_of |
Hepatitis B surface antibody ( anti-HBs ) concentrations were measured before and 1 month after the challenge vaccine dose . | {
"id": "C0369334",
"pos": [
0,
28
],
"name": "Hepatitis B surface antibody"
} | {
"id": "C0201478",
"pos": [
31,
39
],
"name": "anti-HBs"
} | 6component_of |
Another report described two JRA patients who developed nodules while receiving methotrexate . | {
"id": "C0028259",
"pos": [
56,
63
],
"name": "nodules"
} | {
"id": "C0025677",
"pos": [
80,
92
],
"name": "methotrexate"
} | 0NA |
The study confirmed the positive correlation between the length of the hyoid and the weight and height of the subject ( p<0.05 ) . | {
"id": "C1446409",
"pos": [
24,
32
],
"name": "positive"
} | {
"id": "C0005910",
"pos": [
85,
91
],
"name": "weight"
} | 0NA |
CSF from a patient with congenital indifference to pain was found to produce analgesia in the rat following intracerebroventricular injections . | {
"id": "C0030193",
"pos": [
51,
55
],
"name": "pain"
} | {
"id": "C0002766",
"pos": [
77,
86
],
"name": "analgesia"
} | 12focus_of |
Stored ovarian tissue ( for 1 - 10 years ) was rapidly thawed and transplanted into the space between the rectus sheath and the rectus muscle ( 8 - 20 cortical sections per patient ) . | {
"id": "C0040732",
"pos": [
66,
78
],
"name": "transplanted"
} | {
"id": "C0448311",
"pos": [
128,
141
],
"name": "rectus muscle"
} | 0NA |
The phospholipids of normal erythrocytes are arranged asymmetrically across the plasma membrane ; phosphatidylcholine ( PC ) and sphingomyelin are predominantly on the outer surface , whereas others such as phosphatidylserine ( PS ) and phosphatidylethanolamine ( PE ) are predominantly restricted to the inner leaflet . | {
"id": "C1959616",
"pos": [
98,
117
],
"name": "phosphatidylcholine"
} | {
"id": "C0014772",
"pos": [
28,
40
],
"name": "erythrocytes"
} | 0NA |
Obesity is strongly associated with the risks of diabetes and cardiovascular disease , and there is a need to measure the subcutaneous adipose tissue ( SAT ) layer thickness and to understand the distribution of body fat . | {
"id": "C0222331",
"pos": [
122,
149
],
"name": "subcutaneous adipose tissue"
} | {
"id": "C0001527",
"pos": [
212,
220
],
"name": "body fat"
} | 0NA |
Propofol , an intravenous anesthetic drug , is frequently used as an adjunct to transvaginal oocyte retrieval but little is known about its effects upon fertilization , embryo development , and pregnancy rate when used drug the for induction of general anesthesia . | {
"id": "C0013227",
"pos": [
219,
223
],
"name": "drug"
} | {
"id": "C0002915",
"pos": [
245,
263
],
"name": "general anesthesia"
} | 0NA |
We also measured serum vitamin B12 , folate , total plasma homocysteine levels , and HOMA-IR values . | {
"id": "C0019878",
"pos": [
59,
71
],
"name": "homocysteine"
} | {
"id": "C0042845",
"pos": [
23,
34
],
"name": "vitamin B12"
} | 0NA |
Studies in a human subject verified that this behavior is reproduced in vivo and demonstrated that the water and lipid suppression of the new pulse sequence are sufficient for application in prostate cancer patients . | {
"id": "C0023779",
"pos": [
113,
118
],
"name": "lipid"
} | {
"id": "C0043047",
"pos": [
103,
108
],
"name": "water"
} | 0NA |
Bilateral elective , selective or functional neck dissection in every instance of supraglottic cancer was best performed only in those SGSCC patients who were more likely to have occult nodal disease on the basis of biological factors and imaging data . | {
"id": "C0011923",
"pos": [
239,
246
],
"name": "imaging"
} | {
"id": "C1299240",
"pos": [
82,
101
],
"name": "supraglottic cancer"
} | 0NA |
Intravenous injection of trypan blue followed by treatment of the brain according to the Falc-Hillarp was used for morphological study of the blood-brain barrier in control rats and in animals exposed to the 6.5-hour stress . | {
"id": "C0006104",
"pos": [
66,
71
],
"name": "brain"
} | {
"id": "C0041213",
"pos": [
25,
36
],
"name": "trypan blue"
} | 0NA |
Glucocorticoids , immunosuppressive and antiinflammatory agents commonly used in transplantation , are known to inhibit the expression of specific cytokines and growth factors . | {
"id": "C0040732",
"pos": [
81,
96
],
"name": "transplantation"
} | {
"id": "C0079189",
"pos": [
147,
156
],
"name": "cytokines"
} | 0NA |
The past two decades have witnessed a paradigm shift in the treatment of squamous cell carcinoma of the head and neck . | {
"id": "C0018670",
"pos": [
104,
108
],
"name": "head"
} | {
"id": "C0027530",
"pos": [
113,
117
],
"name": "neck"
} | 0NA |
Delay of neonatal arterial switch operation beyond 3 days is significantly associated with increased morbidity and healthcare costs . | {
"id": "C0003842",
"pos": [
18,
26
],
"name": "arterial"
} | {
"id": "C0543467",
"pos": [
34,
43
],
"name": "operation"
} | 0NA |
To determine the time course of enhancement patterns in the aorta and endoleaks at dynamic computed tomographic ( CT ) angiography as well as their effect on the endoleak detection rate in patients who have undergone abdominal aortic endovascular aneurysm repair ( EVAR ) . | {
"id": "C0003483",
"pos": [
60,
65
],
"name": "aorta"
} | {
"id": "C0002978",
"pos": [
119,
130
],
"name": "angiography"
} | 0NA |
We designed a new murine study in order to compare this two methods on different subjects in order to obtain histological proofs of which one is better and to see how limited periosteum removal influence fracture healing . | {
"id": "C0015252",
"pos": [
186,
193
],
"name": "removal"
} | {
"id": "C0031110",
"pos": [
175,
185
],
"name": "periosteum"
} | 0NA |
Physiological testosterone replacement does not adversely affect blood coagulation status . | {
"id": "C0035139",
"pos": [
27,
38
],
"name": "replacement"
} | {
"id": "C0039601",
"pos": [
14,
26
],
"name": "testosterone"
} | 0NA |
The pharmacist and physician adjusted medication to manage each patient 's HbA(1c ) level and blood pressure . | {
"id": "C0013227",
"pos": [
38,
48
],
"name": "medication"
} | {
"id": "C0005823",
"pos": [
94,
108
],
"name": "blood pressure"
} | 0NA |
Thus correction of anemia by EPO reversed insulin resistance and hyperinsulinemia in HD patients with or without iron overload . | {
"id": "C0002871",
"pos": [
19,
25
],
"name": "anemia"
} | {
"id": "C0020459",
"pos": [
65,
81
],
"name": "hyperinsulinemia"
} | 0NA |
A logistical model was used in order to identify the independent and statistical factors associated with the refusal to allow sampling of an organ or tissue . | {
"id": "C0441621",
"pos": [
126,
134
],
"name": "sampling"
} | {
"id": "C0040300",
"pos": [
150,
156
],
"name": "tissue"
} | 0NA |
Physical exam revealed spontaneous nystagmus to the left . | {
"id": "C0031809",
"pos": [
0,
13
],
"name": "Physical exam"
} | {
"id": "C0349681",
"pos": [
23,
44
],
"name": "spontaneous nystagmus"
} | 0NA |
Autopsy revealed multiple residual thrombi in the main branches of the abdominal aorta and necrosis of the abdominal organs despite a patent thoracoabdominal aorta . | {
"id": "C0087086",
"pos": [
35,
42
],
"name": "thrombi"
} | {
"id": "C0003484",
"pos": [
71,
86
],
"name": "abdominal aorta"
} | 0NA |
Norepinephrine infusion ( 600 ng/min ) produced a similar degree of hypertension , but did not affect glomerular proliferation in nephritic rats . | {
"id": "C0020538",
"pos": [
68,
80
],
"name": "hypertension"
} | {
"id": "C0574032",
"pos": [
15,
23
],
"name": "infusion"
} | 0NA |
We demonstrate a method generally applicable for the attachment of proteins to oxide surfaces . | {
"id": "C0033684",
"pos": [
67,
75
],
"name": "proteins"
} | {
"id": "C0185023",
"pos": [
53,
63
],
"name": "attachment"
} | 0NA |
On the other hand , neurons may be obtained from adult stem cells from other tissues , such as the bone marrow or adipose tissue , which means a practically unendable source of neural precursors , either by direct implant after their selection or after their in vitro culture . | {
"id": "C0005953",
"pos": [
99,
110
],
"name": "bone marrow"
} | {
"id": "C0040300",
"pos": [
77,
84
],
"name": "tissues"
} | 0NA |
Warfarin maintenance dose was predicted for all subjects based on FDA approved genotype-based dose estimates from revised COUMADIN medication guide . | {
"id": "C0013227",
"pos": [
131,
141
],
"name": "medication"
} | {
"id": "C0043031",
"pos": [
0,
8
],
"name": "Warfarin"
} | 0NA |
Considering the considerable difficult in implementing the necessary pharmacological modifications and the high percentage of possible complications involved in these procedures , maximum interdisciplinary cooperation is recommended with heart surgery colleagues so as to carry out dental treatment in good time in patients who are candidates for heart and large vessel operations . | {
"id": "C0018787",
"pos": [
347,
352
],
"name": "heart"
} | {
"id": "C0018821",
"pos": [
238,
251
],
"name": "heart surgery"
} | 19procedure_site_of |
Edema and glia : From 2 up to 30 days after avulsion perivascular edema was noted around blood vessels and polymorphonuclear granulocytes were found mainly in the peri-endothelial space . | {
"id": "C0005847",
"pos": [
89,
102
],
"name": "blood vessels"
} | {
"id": "C0185044",
"pos": [
44,
52
],
"name": "avulsion"
} | 0NA |
We report a rare case of massive inguinoscrotal bladder herniation with ureter , causing urinary stasis on bone scintigraphy . | {
"id": "C0019270",
"pos": [
56,
66
],
"name": "herniation"
} | {
"id": "C0041951",
"pos": [
72,
78
],
"name": "ureter"
} | 0NA |
Some tumours usually appear more frequently in persons with prior malnutrition or excessive consumption of alcohol or tobacco . | {
"id": "C0027651",
"pos": [
5,
12
],
"name": "tumours"
} | {
"id": "C0040329",
"pos": [
118,
125
],
"name": "tobacco"
} | 0NA |
By assessing the relative incidence of readily identifiable malformations of the limb and palate associated with various doses of the two isomers , we found that 13-cis retinoic acid was four to eight times less embryopathic than all-trans retinoic acid . | {
"id": "C0040845",
"pos": [
230,
253
],
"name": "all-trans retinoic acid"
} | {
"id": "C0022265",
"pos": [
162,
182
],
"name": "13-cis retinoic acid"
} | 0NA |
Refractory coronary vasospasm subsequent to reperfusion , such as cardiopulmonary resuscitation or revascularization , for myocardial infarction may respond to fasudil in the superacute phase . | {
"id": "C0007203",
"pos": [
66,
95
],
"name": "cardiopulmonary resuscitation"
} | {
"id": "C0027051",
"pos": [
123,
144
],
"name": "myocardial infarction"
} | 0NA |
Studies conducted in patients who acquired hepatitis C by blood transfusion 15 - 25 years ago indicate that 20 - 30 % of them have now progressed to cirrhosis , including 5 - 10 % with end stage liver disease and 4 - 8 % who died of liver-related causes . | {
"id": "C0005841",
"pos": [
58,
75
],
"name": "blood transfusion"
} | {
"id": "C0019196",
"pos": [
43,
54
],
"name": "hepatitis C"
} | 0NA |
In this study , expression of the c-erbB-2 gene in tumors and healthy tissue of patients with ovarian cancer was investigated . | {
"id": "C0027651",
"pos": [
51,
57
],
"name": "tumors"
} | {
"id": "C0919267",
"pos": [
94,
108
],
"name": "ovarian cancer"
} | 3associated_morphology_of |
To track the fate of labeled cells , in four patients a repeat biopsy was obtained 7 - 14 days after the iododeoxyuridine/bromodeoxyuridine infusion . | {
"id": "C0005558",
"pos": [
63,
69
],
"name": "biopsy"
} | {
"id": "C0574032",
"pos": [
140,
148
],
"name": "infusion"
} | 0NA |
We investigated the interaction between hip and ankle joints during walking to determine the effects of different ankle pushoff instructions on hip biomechanics in patients with THA . | {
"id": "C0003087",
"pos": [
48,
60
],
"name": "ankle joints"
} | {
"id": "C0019552",
"pos": [
40,
43
],
"name": "hip"
} | 0NA |
A 27-year-old man presented with 10 days of nausea , vomiting , and headache and was found to have a large intraventricular mass emanating from the choroid plexus with resultant hydrocephalus . | {
"id": "C0008524",
"pos": [
148,
162
],
"name": "choroid plexus"
} | {
"id": "C0042963",
"pos": [
53,
61
],
"name": "vomiting"
} | 0NA |
Pregnant rats were treated with 44 , 88 and 176 Medical Research Council munits of thyrocalcitonin ( TCT ) twice daily during days 10 to 21 of gestation . | {
"id": "C0006668",
"pos": [
83,
98
],
"name": "thyrocalcitonin"
} | {
"id": "C0677634",
"pos": [
101,
104
],
"name": "TCT"
} | 0NA |
A positive correlation was found between leptin and total body fat ( r = 0.83 ; P < 0.0001 ) and when fat was expressed as a percentage of body weight ( r = 0.86 ; P < 0.0001 ) . | {
"id": "C1446409",
"pos": [
2,
10
],
"name": "positive"
} | {
"id": "C0005910",
"pos": [
139,
150
],
"name": "body weight"
} | 0NA |
By routine ultrasound examination of the brain an echogenic structure was seen , which was radiographically diagnosed as a nasogastric tube . | {
"id": "C0006104",
"pos": [
41,
46
],
"name": "brain"
} | {
"id": "C0085678",
"pos": [
123,
139
],
"name": "nasogastric tube"
} | 0NA |
Pre-analytical issues are also being dealt with in some newer instrumentation , which are able to detect hemolysis , icteria and lipemia , and , in some cases , other issues related to sample collection such as tube under-filling . | {
"id": "C0442726",
"pos": [
98,
104
],
"name": "detect"
} | {
"id": "C0200345",
"pos": [
185,
202
],
"name": "sample collection"
} | 0NA |
Cataract can only be cured by surgery during which the cloudy lens is replaced with an artificial intraocular lens . | {
"id": "C0023317",
"pos": [
62,
66
],
"name": "lens"
} | {
"id": "C0086543",
"pos": [
0,
8
],
"name": "Cataract"
} | 11finding_site_of |
The clinical examination , X-ray diagnostics and if necessary computed tomography allow the classification into stable and unstable fractures . | {
"id": "C0031809",
"pos": [
4,
24
],
"name": "clinical examination"
} | {
"id": "C0040405",
"pos": [
62,
81
],
"name": "computed tomography"
} | 0NA |
Deactivation was attenuated by applying caffeine ( 100 microM ) and blocked with high extracellular Ca(2 + ) ( 56 mM ) . | {
"id": "C0028778",
"pos": [
68,
75
],
"name": "blocked"
} | {
"id": "C0006644",
"pos": [
40,
48
],
"name": "caffeine"
} | 0NA |
Phosphocreatine ( PCr ) is a natural compound , which has been used in cardiac disease and cardiopulmonary resuscitation . | {
"id": "C0018799",
"pos": [
71,
86
],
"name": "cardiac disease"
} | {
"id": "C0007203",
"pos": [
91,
120
],
"name": "cardiopulmonary resuscitation"
} | 0NA |
The radioactivity levels obtained in several tissues , after the intravenous injections of these telomers in mice bearing grafted B16 syngenic melanoma showed that the addition of a RGD residue to a telomeric structure confers it an increased affinity for the highly vascularized zone surrounding the tumor . | {
"id": "C0027651",
"pos": [
301,
306
],
"name": "tumor"
} | {
"id": "C0040300",
"pos": [
45,
52
],
"name": "tissues"
} | 0NA |
Medication adherence is associated with all-cause and heart failure-related hospitalisation and death in heart failure . | {
"id": "C0018787",
"pos": [
54,
59
],
"name": "heart"
} | {
"id": "C0018801",
"pos": [
105,
118
],
"name": "heart failure"
} | 11finding_site_of |
We used a questionnaire to register the lung and joint symptoms and all participants were offered a clinical evaluation with standardized interview and physical examination , including a count of the number of painful and/or inflamed joints . | {
"id": "C1261322",
"pos": [
100,
119
],
"name": "clinical evaluation"
} | {
"id": "C0031809",
"pos": [
152,
172
],
"name": "physical examination"
} | 17method_of |
Our patients successfully received arch reconstruction , pulmonary debanding and patch closure of the ventricular septal defect at the age of 2 or 3 months after birth with a body weight of 3.5 and 4.5 kg , respectively . | {
"id": "C0185003",
"pos": [
87,
94
],
"name": "closure"
} | {
"id": "C0005910",
"pos": [
175,
186
],
"name": "body weight"
} | 0NA |
Predeposit autologous donation for elective surgical procedures during which there is a potential requirement for transfusion is medically proven as safe and efficacious but significantly underutilized . | {
"id": "C0005841",
"pos": [
114,
125
],
"name": "transfusion"
} | {
"id": "C0543467",
"pos": [
44,
63
],
"name": "surgical procedures"
} | 0NA |
Aim of this study was the assessment of the prevalence of coeliac disease ( CD ) in children attending the secondary school in the city of Padua . | {
"id": "C0031809",
"pos": [
26,
36
],
"name": "assessment"
} | {
"id": "C0007570",
"pos": [
58,
73
],
"name": "coeliac disease"
} | 0NA |
In the vast majority of cases relief of obstruction cures hypertension . | {
"id": "C0028778",
"pos": [
40,
51
],
"name": "obstruction"
} | {
"id": "C0020538",
"pos": [
58,
70
],
"name": "hypertension"
} | 0NA |
Whether the appearance of the malignant lymphoma is a consequence of Whipple 's disease or a second neoplastic disease remains to be answered by further epidemiological studies . | {
"id": "C0027651",
"pos": [
100,
118
],
"name": "neoplastic disease"
} | {
"id": "C0024299",
"pos": [
30,
48
],
"name": "malignant lymphoma"
} | 0NA |
The most frequent clinical signs associated with IPA were cough ( 92 % ) , chest pain ( 76 % ) , and hemoptysis ( 54 % ) . | {
"id": "C0019079",
"pos": [
101,
111
],
"name": "hemoptysis"
} | {
"id": "C0008031",
"pos": [
75,
85
],
"name": "chest pain"
} | 0NA |
Technical problems occurred 23 times , with 11 devices ceasing to function before removal , seven becoming displaced , and five microventricular catheters failing to enter the ventricles . | {
"id": "C0007799",
"pos": [
176,
186
],
"name": "ventricles"
} | {
"id": "C0015252",
"pos": [
82,
89
],
"name": "removal"
} | 0NA |
It is of interest that Fgf-3 expression was also observed in the primary enamel knot , a putative signaling center of the tooth , whereas no transcripts were seen in the secondary enamel knots that appear in the tips of future cusps of the bell stage tooth germs . | {
"id": "C0040426",
"pos": [
122,
127
],
"name": "tooth"
} | {
"id": "C0339897",
"pos": [
212,
216
],
"name": "tips"
} | 0NA |
The frequency of ulcerated plaques of the subclavio-vertebral intersection is probably underestimated in the literature Labauge et al. ( 1987 ) emphasized recently the risk of cerebellar infarction during the natural history of vertebral artery occlusion . | {
"id": "C0041582",
"pos": [
17,
26
],
"name": "ulcerated"
} | {
"id": "C0236073",
"pos": [
176,
197
],
"name": "cerebellar infarction"
} | 0NA |
DMCs were found in specimens having intestinal carcinomas either in the cardia , the corpus or the antrum . | {
"id": "C0007144",
"pos": [
72,
78
],
"name": "cardia"
} | {
"id": "C0227813",
"pos": [
85,
91
],
"name": "corpus"
} | 0NA |
Circulating leukocyte counts , granulocyte colony-stimulating factor and interleukin-6 levels , and pulmonary function were determined at regular intervals in 39 expedition members . | {
"id": "C0021760",
"pos": [
73,
86
],
"name": "interleukin-6"
} | {
"id": "C0023508",
"pos": [
12,
28
],
"name": "leukocyte counts"
} | 0NA |
The retinal pigment epithelium ( RPE ) is involved in the pathogenesis of age-related macular degeneration . | {
"id": "C0035298",
"pos": [
4,
11
],
"name": "retinal"
} | {
"id": "C0035322",
"pos": [
33,
36
],
"name": "RPE"
} | 0NA |
Also hydralazine showed favorable hemodynamic results in few cases but exacerbated pulmonary hypertension in others.(ABSTRACT TRUNCATED AT 250 WORDS ) | {
"id": "C0020223",
"pos": [
5,
16
],
"name": "hydralazine"
} | {
"id": "C0020542",
"pos": [
83,
105
],
"name": "pulmonary hypertension"
} | 0NA |
Contractile responses to noradrenaline were significantly enhanced after hemorrhage , whereas relaxations to acetylcholine , ATP , and adenosine were significantly reduced . | {
"id": "C0001480",
"pos": [
125,
128
],
"name": "ATP"
} | {
"id": "C0001443",
"pos": [
135,
144
],
"name": "adenosine"
} | 16is_modification_of |
Delayed SHC or WBC , initiated 3 h after HI , does not reduce pathology in the brain nor in organs . | {
"id": "C0006104",
"pos": [
79,
84
],
"name": "brain"
} | {
"id": "C0023508",
"pos": [
15,
18
],
"name": "WBC"
} | 0NA |
Sleeping sickness and Chagas disease are among the most severe diseases in Africa as well as Latin America . | {
"id": "C0012634",
"pos": [
63,
71
],
"name": "diseases"
} | {
"id": "C0041228",
"pos": [
0,
17
],
"name": "Sleeping sickness"
} | 0NA |
This article reviews the literature on drug-induced urinary retention and focuses on its incidence , the different classes of drugs that have been associated with it , and options for its management and prevention . | {
"id": "C0013227",
"pos": [
126,
131
],
"name": "drugs"
} | {
"id": "C0080274",
"pos": [
52,
69
],
"name": "urinary retention"
} | 0NA |
Organ weights at autopsy showed two changes , one of which was increased kidney weights which , although not present in every generation , seemed to be related to treatment . | {
"id": "C0022646",
"pos": [
73,
79
],
"name": "kidney"
} | {
"id": "C0004398",
"pos": [
17,
24
],
"name": "autopsy"
} | 0NA |
Cancer screening is a major healthcare issue . | {
"id": "C0006826",
"pos": [
0,
6
],
"name": "Cancer"
} | {
"id": "C0199230",
"pos": [
7,
16
],
"name": "screening"
} | 12focus_of |
Each participant was asked to rate the difficulty of intubation ( 1=very easy ; 5=very difficult ) . | {
"id": "C1299586",
"pos": [
39,
49
],
"name": "difficulty"
} | {
"id": "C0021925",
"pos": [
53,
63
],
"name": "intubation"
} | 0NA |
Recently , we showed that multiscale entropy ( MSE ) , a non-linear method for analysis of heart rate variability ( HRV ) , is an early outcome predictor in non-atrial fibrillation ( non-AF ) stroke patients . | {
"id": "C0038454",
"pos": [
192,
198
],
"name": "stroke"
} | {
"id": "C0018810",
"pos": [
91,
101
],
"name": "heart rate"
} | 0NA |
It is concluded that children with the symptomocomplex characterized by low level of pneumatization of the mastoid process , conductive or mixed hearing loss with a bone-air interval of 30 - 50 dB , and type B tympanogram are in need of early surgical intervention . | {
"id": "C0446908",
"pos": [
107,
122
],
"name": "mastoid process"
} | {
"id": "C0155552",
"pos": [
139,
157
],
"name": "mixed hearing loss"
} | 0NA |
Neoplastic lesions in the biliary tree were histologically examined , and the presence and degree of cholangitis was also evaluated with special reference to biliary carcinogenesis . | {
"id": "C0005423",
"pos": [
26,
38
],
"name": "biliary tree"
} | {
"id": "C0008311",
"pos": [
101,
112
],
"name": "cholangitis"
} | 11finding_site_of |
Common intestinal parasitic infections which were detected in both the populations were Giardia intestinalis ( 28.2 % ) and Blastocystis hominis ( 27.5 % ) . | {
"id": "C0021853",
"pos": [
7,
17
],
"name": "intestinal"
} | {
"id": "C0030499",
"pos": [
18,
38
],
"name": "parasitic infections"
} | 0NA |
Effective stimulation of all the IgG isotypes , particularly IgG2a , after immunization with liposome encapsulated antigens seems to be responsible for the significant levels of resistance against the disease . | {
"id": "C1292856",
"pos": [
10,
21
],
"name": "stimulation"
} | {
"id": "C0020971",
"pos": [
75,
87
],
"name": "immunization"
} | 0NA |
The LC analyses were carried out using a mobile phase composed of acetonitrile , 2-propanol and water , under gradient elution . | {
"id": "C0022237",
"pos": [
81,
91
],
"name": "2-propanol"
} | {
"id": "C0043047",
"pos": [
96,
101
],
"name": "water"
} | 0NA |
Core rectal temperatures ( T(C ) ) , intramuscular temperatures ( T(IM ) ) , skin temperatures ( T(SK ) ) , heart rate ( HR ) , oxygen uptake ( VO(2 ) ) , sweat rate ( SR ) , and plasma cortisol were measured . | {
"id": "C0037294",
"pos": [
77,
94
],
"name": "skin temperatures"
} | {
"id": "C0018810",
"pos": [
108,
118
],
"name": "heart rate"
} | 0NA |
PET images of a patient with recurrent prostate cancer showed uptake of FCH in the prostatic bed and in metastases to lymph nodes . | {
"id": "C0033572",
"pos": [
83,
92
],
"name": "prostatic"
} | {
"id": "C0376358",
"pos": [
39,
54
],
"name": "prostate cancer"
} | 11finding_site_of |
Retinal ischemia and reperfusion ( I/R ) is extensively involved in ocular diseases , causing retinal ganglion cell ( RGCs ) death resulting in visual impairment and blindness . | {
"id": "C0035298",
"pos": [
0,
7
],
"name": "Retinal"
} | {
"id": "C0022116",
"pos": [
8,
16
],
"name": "ischemia"
} | 0NA |
In older patients with age-related macular degeneration ( AMD ) , however , hypertrophy of the retinal pigment epithelium ( RPE ) is known to occur but has not previously been reported to be associated with CNV regression . | {
"id": "C0035298",
"pos": [
95,
102
],
"name": "retinal"
} | {
"id": "C0035322",
"pos": [
124,
127
],
"name": "RPE"
} | 0NA |
When cryopreserving human ovaries using the same protocol , over 95 % protection against cryodamage was observed on all tissue levels . | {
"id": "C0029939",
"pos": [
26,
33
],
"name": "ovaries"
} | {
"id": "C0040300",
"pos": [
120,
126
],
"name": "tissue"
} | 0NA |
The kidney volume was correlated to somatometric data including body weight and body length , breadth of thorax , and head circumference . | {
"id": "C0022646",
"pos": [
4,
10
],
"name": "kidney"
} | {
"id": "C0817096",
"pos": [
105,
111
],
"name": "thorax"
} | 0NA |
They usually penetrated the infarcted focus to drain into the papillary muscles and trabeculae carnae . | {
"id": "C0013103",
"pos": [
47,
52
],
"name": "drain"
} | {
"id": "C0030352",
"pos": [
62,
79
],
"name": "papillary muscles"
} | 0NA |
Ex vivo magnetic resonance imaging and diffusion tensor imaging analyses of NgR1 overexpressing brains did not reveal any major alterations . | {
"id": "C0006104",
"pos": [
96,
102
],
"name": "brains"
} | {
"id": "C0024485",
"pos": [
8,
34
],
"name": "magnetic resonance imaging"
} | 0NA |
In 21 cases ( 2.6 % ) fewer than four parathyroid glands were macroscopically found at the initial operation . | {
"id": "C0543467",
"pos": [
99,
108
],
"name": "operation"
} | {
"id": "C0030518",
"pos": [
38,
56
],
"name": "parathyroid glands"
} | 0NA |
Pellet and supernatant preparations from homogenised , pooled samples of liver and kidney were subjected to chromatographic separation . | {
"id": "C0022646",
"pos": [
83,
89
],
"name": "kidney"
} | {
"id": "C0023884",
"pos": [
73,
78
],
"name": "liver"
} | 0NA |
Since the observed time course and regional differences in c-fos expression are in good agreement with the cognitive and memory deficits observed after human TBI it can be utilized in further investigations , especially to test the effects of various forms of pharmacological or cellular therapy . | {
"id": "C1261322",
"pos": [
192,
206
],
"name": "investigations"
} | {
"id": "C0022885",
"pos": [
223,
227
],
"name": "test"
} | 17method_of |
The use of specific antiidiotypic antibodies allowed comparison of the variable regions of the two M-components and investigation of their cellular origin as well as their presence in vasculitis lesions . | {
"id": "C0221198",
"pos": [
195,
202
],
"name": "lesions"
} | {
"id": "C0042384",
"pos": [
184,
194
],
"name": "vasculitis"
} | 0NA |
We sought to examine whether cap-assisted hemoclip application is effective in controlling ES-induced hemorrhage . | {
"id": "C0019080",
"pos": [
102,
112
],
"name": "hemorrhage"
} | {
"id": "C0185125",
"pos": [
51,
62
],
"name": "application"
} | 0NA |
Treatment consisted of open reduction with internal fixation of the fractures and ligamentous repair through a combined dorsal and palmar approach . | {
"id": "C0016658",
"pos": [
68,
77
],
"name": "fractures"
} | {
"id": "C0016642",
"pos": [
43,
60
],
"name": "internal fixation"
} | 8direct_morphology_of |
DNA damage response and repair are carried out by certain proteins following damage by environmental clastogens , such as ionizing radiation and reactive oxygen species . | {
"id": "C0010957",
"pos": [
77,
83
],
"name": "damage"
} | {
"id": "C0043240",
"pos": [
24,
30
],
"name": "repair"
} | 0NA |
Although neutrophils are an important component of the inflammatory response that characterizes acute lung injury , there is little information to suggest that they are capable of initiating cytokine-mediated immune responses in the lung . | {
"id": "C0024109",
"pos": [
233,
237
],
"name": "lung"
} | {
"id": "C0242488",
"pos": [
96,
113
],
"name": "acute lung injury"
} | 11finding_site_of |
Obesity is associated with colon cancer pathogenesis , but the underlying mechanism is actively debated . | {
"id": "C0028754",
"pos": [
0,
7
],
"name": "Obesity"
} | {
"id": "C0007102",
"pos": [
27,
39
],
"name": "colon cancer"
} | 0NA |
A conclusion is made on the rationale and efficacy of an assist extracorporeal circulation in severe traumatic shock , that would make is possible to perform an early operation and to eliminate " the trigger mechanism " of shock . | {
"id": "C0543467",
"pos": [
167,
176
],
"name": "operation"
} | {
"id": "C0015354",
"pos": [
64,
90
],
"name": "extracorporeal circulation"
} | 0NA |
The effects are related to dose of estrogen and type of progestin . | {
"id": "C0014939",
"pos": [
35,
43
],
"name": "estrogen"
} | {
"id": "C0033306",
"pos": [
56,
65
],
"name": "progestin"
} | 0NA |
Especially directed to otolaryngologists , this paper describes the technique of in vivo OCT imaging of the larynx in detail during microlaryngoscopy and supplies a number of personal hints . | {
"id": "C0023078",
"pos": [
108,
114
],
"name": "larynx"
} | {
"id": "C0456202",
"pos": [
132,
149
],
"name": "microlaryngoscopy"
} | 9direct_procedure_site_of |
We conclude that interaction between mammary epithelium and other specific nonepithelial cells markedly influences the acquisition of hormone sensitivity of the epithelium and hormone-dependent differentiation . | {
"id": "C0019932",
"pos": [
134,
141
],
"name": "hormone"
} | {
"id": "C0037420",
"pos": [
17,
28
],
"name": "interaction"
} | 0NA |
Magnetic resonance imaging revealed a dense mass that occupied the entire right sphenoidal sinus and skull base with typical ground-glass opacification and bony sclerosis of the whole sphenoidal wall . | {
"id": "C0577559",
"pos": [
44,
48
],
"name": "mass"
} | {
"id": "C0024485",
"pos": [
0,
26
],
"name": "Magnetic resonance imaging"
} | 0NA |
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