text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Both patients had successful femoral intramedullary skeletal kinetic distractor implantation and were transferred for acute inpatient rehabilitation . | {
"id": "C0015811",
"pos": [
29,
36
],
"name": "femoral"
} | {
"id": "C0021107",
"pos": [
80,
92
],
"name": "implantation"
} | 0NA |
The suitable prevention for CMV infection and disease in accordance with the immunological status of transplant recipients will be established in the near future . | {
"id": "C0012634",
"pos": [
46,
53
],
"name": "disease"
} | {
"id": "C0475806",
"pos": [
150,
154
],
"name": "near"
} | 0NA |
We conclude that a combination of ( BV ) chemotherapy and ZDV can be used safely with high response rates . | {
"id": "C0013216",
"pos": [
41,
53
],
"name": "chemotherapy"
} | {
"id": "C0043474",
"pos": [
58,
61
],
"name": "ZDV"
} | 0NA |
To that end , the goal of this study was to assess patient exposure to these leachables after reconstitution , storage , and administration of the lyophilized drug . | {
"id": "C0013227",
"pos": [
159,
163
],
"name": "drug"
} | {
"id": "C0274281",
"pos": [
59,
67
],
"name": "exposure"
} | 0NA |
In these experiments PLC transition into overt AML seemed to be dependent on their transfer into irradiated recipients . | {
"id": "C0023467",
"pos": [
47,
50
],
"name": "AML"
} | {
"id": "C1522449",
"pos": [
97,
107
],
"name": "irradiated"
} | 0NA |
Cocaine abuse is associated with a number of cardiovascular complications that include arrhythmias and sudden cardiac death . | {
"id": "C0007226",
"pos": [
45,
59
],
"name": "cardiovascular"
} | {
"id": "C0003811",
"pos": [
87,
98
],
"name": "arrhythmias"
} | 0NA |
GlgE combines many favorable properties that make it a highly attractive novel drug target for chemotherapy of TB . | {
"id": "C0013227",
"pos": [
79,
83
],
"name": "drug"
} | {
"id": "C0013216",
"pos": [
95,
107
],
"name": "chemotherapy"
} | 10direct_substance_of |
There were no fistulas and only one stricture in the meatal based flap repairs . | {
"id": "C1261287",
"pos": [
36,
45
],
"name": "stricture"
} | {
"id": "C0016169",
"pos": [
14,
22
],
"name": "fistulas"
} | 0NA |
However , several in vivo studies in the nervous system indicate that curtailing UPR function either exacerbates disease or may reduce severity through unexpected or unidentified pathways . | {
"id": "C0027763",
"pos": [
41,
55
],
"name": "nervous system"
} | {
"id": "C0012634",
"pos": [
113,
120
],
"name": "disease"
} | 0NA |
The objective of this study was to compare the incidence of hand-foot syndrome ( HFS ) in patients who received pyridoxine versus placebo during pegylated liposomal doxorubicin ( PLD ) chemotherapy for recurrent ovarian , breast , or endometrial cancer . | {
"id": "C0006141",
"pos": [
222,
228
],
"name": "breast"
} | {
"id": "C2745948",
"pos": [
81,
84
],
"name": "HFS"
} | 0NA |
Among several protein spots showing differential expression , one , hemopexin ( HPX ) , was identified as upregulated in indomethacin-induced injured intestinal mucosa using the MASCOT search engine . | {
"id": "C0019067",
"pos": [
68,
77
],
"name": "hemopexin"
} | {
"id": "C0523688",
"pos": [
80,
83
],
"name": "HPX"
} | 6component_of |
Elucidating these unknowns will be important in understanding mechanisms and possible therapeutic targets in autoimmune , inflammatory , and metastatic diseases . | {
"id": "C0443146",
"pos": [
109,
119
],
"name": "autoimmune"
} | {
"id": "C0087111",
"pos": [
86,
97
],
"name": "therapeutic"
} | 0NA |
Addition of steroids to the culture medium ( MT or estradiol at 10 nM for 2 days ) enabled a GH response to sGnRH stimulation in cells from sexually regressed fish . | {
"id": "C1292856",
"pos": [
114,
125
],
"name": "stimulation"
} | {
"id": "C0038317",
"pos": [
12,
20
],
"name": "steroids"
} | 0NA |
Plasma concentrations of testosterone , androstenedione and progesterone in freemartins , and normal cyclic and non-cyclic heifers were studied . | {
"id": "C0039601",
"pos": [
25,
37
],
"name": "testosterone"
} | {
"id": "C0033308",
"pos": [
60,
72
],
"name": "progesterone"
} | 0NA |
By using a single continuous metric for PA levels , we were able to make a comparison of the effect of PA on CVD incidence and mortality including myocardial infarct ( MI ) , stroke , and heart failure , as well as T2DM . | {
"id": "C0018801",
"pos": [
188,
201
],
"name": "heart failure"
} | {
"id": "C0038454",
"pos": [
175,
181
],
"name": "stroke"
} | 0NA |
DNA double-strand breaks ( DSBs ) are among the most cytotoxic types of DNA damage , which if left unrepaired can lead to mutations or gross chromosomal aberrations , and promote the onset of diseases associated with genomic instability such as cancer . | {
"id": "C0006826",
"pos": [
245,
251
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
192,
200
],
"name": "diseases"
} | 0NA |
The object of this study was to determine the relative usefulness of clinical and radiographic indices in the diagnosis of patients with low skeletal bone mass amongst 135 healthy perimenopausal women , aged 45 - 55 years , attending for routine dental treatment . | {
"id": "C0262950",
"pos": [
141,
154
],
"name": "skeletal bone"
} | {
"id": "C3839366",
"pos": [
180,
194
],
"name": "perimenopausal"
} | 0NA |
Bronchoalveolar lavage has been suggested to be of value in establishing the diagnosis of pneumonia , because the cells and liquid recovered can be examined microscopically immediately after the procedure and are also suitable for quantitative culture . | {
"id": "C0032285",
"pos": [
90,
99
],
"name": "pneumonia"
} | {
"id": "C0184661",
"pos": [
195,
204
],
"name": "procedure"
} | 0NA |
Nevertheless , further investigations are required to clarify many pending issues , especially those relative to the assessment of benefits and risks when using cannabis for therapeutic purposes , thereby also helping national and federal jurisdictions to remain updated . | {
"id": "C1261322",
"pos": [
23,
37
],
"name": "investigations"
} | {
"id": "C0031809",
"pos": [
117,
127
],
"name": "assessment"
} | 17method_of |
Computed tomographic follow-up showed complete thrombosis with or without later regression of the false lumen in the descending thoracic aorta in 9 patients ( 69.2 % ) . | {
"id": "C1522460",
"pos": [
117,
142
],
"name": "descending thoracic aorta"
} | {
"id": "C0524461",
"pos": [
104,
109
],
"name": "lumen"
} | 0NA |
We performed in 484 patient 's stone composition and found calcium oxalate stones related to idiopathic hypercalciuria predominantly while uric acid stones to unduly acidic urine . | {
"id": "C0006736",
"pos": [
31,
36
],
"name": "stone"
} | {
"id": "C0403719",
"pos": [
139,
155
],
"name": "uric acid stones"
} | 0NA |
The relative order of potency was determined as thioridazine greater than clomipramine greater than fluoxetine . | {
"id": "C0009010",
"pos": [
74,
86
],
"name": "clomipramine"
} | {
"id": "C0039943",
"pos": [
48,
60
],
"name": "thioridazine"
} | 0NA |
The developed methods were proved to be specific , sensitive and precise for quality control of the investigated drugs in their pharmaceutical dosage form without the need for any separation process . | {
"id": "C0013227",
"pos": [
113,
118
],
"name": "drugs"
} | {
"id": "C0020517",
"pos": [
51,
60
],
"name": "sensitive"
} | 0NA |
Shortage of nurses is a long-standing problem which was the subject of official inquiries long before the launch of the NHS . | {
"id": "C0033213",
"pos": [
38,
45
],
"name": "problem"
} | {
"id": "C0796085",
"pos": [
120,
123
],
"name": "NHS"
} | 0NA |
Autopsy in one patient confirmed endocardial fibroelastosis and electron microscopy of fibroblasts in the myocardium showed distention with membrane-bound vacuoles , consistent with a mucopolysaccharidosis . | {
"id": "C0012359",
"pos": [
124,
134
],
"name": "distention"
} | {
"id": "C0004398",
"pos": [
0,
7
],
"name": "Autopsy"
} | 0NA |
An upregulated expression of brain 5LOX , for example during aging and in multiple sclerosis , has been associated with increased vulnerability to neurodegeneration . | {
"id": "C0006104",
"pos": [
29,
34
],
"name": "brain"
} | {
"id": "C0026769",
"pos": [
74,
92
],
"name": "multiple sclerosis"
} | 0NA |
Direct measurements of hemodynamic parameters may improve cardiovascular outcomes by providing rational bases for intervention . | {
"id": "C0007226",
"pos": [
58,
72
],
"name": "cardiovascular"
} | {
"id": "C0184661",
"pos": [
114,
126
],
"name": "intervention"
} | 0NA |
These kinetic data were then used in a MatLab simulation , which showed the feasibility of selenium redox cycling by GSH in the presence of the cellular oxidant , peroxynitrite . | {
"id": "C0036581",
"pos": [
91,
99
],
"name": "selenium"
} | {
"id": "C0017817",
"pos": [
117,
120
],
"name": "GSH"
} | 0NA |
The reduced drug accumulation based on enhanced drug efflux and metabolic capacity , identified in triclabendazole (TCBZ)-resistant Fasciola hepatica may contribute to the development of resistance to TCBZ . | {
"id": "C0013227",
"pos": [
12,
16
],
"name": "drug"
} | {
"id": "C0077071",
"pos": [
99,
114
],
"name": "triclabendazole"
} | 0NA |
Finally , in patients who have been treated surgically , the disorders related to recurrence of their valvular disease or to the dysfunction of their valvular prosthesis also have to be identified . | {
"id": "C0012634",
"pos": [
61,
70
],
"name": "disorders"
} | {
"id": "C0543467",
"pos": [
44,
54
],
"name": "surgically"
} | 0NA |
Even in the absence of hypertension , adiposity induces structural and functional changes in the heart through hemodynamic and non hemodynamic factors . | {
"id": "C0018787",
"pos": [
97,
102
],
"name": "heart"
} | {
"id": "C0020538",
"pos": [
23,
35
],
"name": "hypertension"
} | 0NA |
Finally , the adhesion of PDMS cross-linked networks to SAM surfaces depends on the concentration of interfacial H-bonding . | {
"id": "C0001511",
"pos": [
14,
22
],
"name": "adhesion"
} | {
"id": "C0036002",
"pos": [
56,
59
],
"name": "SAM"
} | 0NA |
Measurements included anthropometry ; body composition indicators ; CD4 count , haemoglobin and albumin ; as well as incidence rates of opportunistic infections ; depression and quality of life scores . | {
"id": "C0001924",
"pos": [
96,
103
],
"name": "albumin"
} | {
"id": "C0019046",
"pos": [
80,
91
],
"name": "haemoglobin"
} | 0NA |
The average of blood loss was 1,450 ml in operation but it became 500 - 800 ml when had a selective preoperative angiography embolization . | {
"id": "C0543467",
"pos": [
42,
51
],
"name": "operation"
} | {
"id": "C0019080",
"pos": [
15,
25
],
"name": "blood loss"
} | 0NA |
Arrhythmias that are detected by ECG during or after the labour in patients with no cardiovascular pathology display a benign nature and do not create any clinical risk for the mother and the baby . | {
"id": "C0007226",
"pos": [
84,
98
],
"name": "cardiovascular"
} | {
"id": "C0003811",
"pos": [
0,
11
],
"name": "Arrhythmias"
} | 0NA |
Several co-morbidities were significantly associated with both costs and mortality ( p < 0.001 ): acute myocardial infarction ; congestive heart failure ; cerebrovascular disease ; lung cancer ; cardiac arrhythmias ; pulmonary circulation disorders ; and weight loss . | {
"id": "C0003811",
"pos": [
195,
214
],
"name": "cardiac arrhythmias"
} | {
"id": "C0018802",
"pos": [
128,
152
],
"name": "congestive heart failure"
} | 0NA |
Finally , The expression of β-catenin protein was demonstrated by fluorescence confocal microscopy and the interaction between β-catenin and Bcl-9 was detected by co-immunoprecipitation . | {
"id": "C0442726",
"pos": [
151,
159
],
"name": "detected"
} | {
"id": "C0037420",
"pos": [
107,
118
],
"name": "interaction"
} | 0NA |
In periodontitis tissues , TWEAK and Fn14 proteins were mainly expressed by mononuclear leukocytes ( morphologically resembling lymphocytes and plasma cells ) , by cells lining blood vessels , by spindle-shaped cells resembling fibroblasts and by multinucleated cells . | {
"id": "C0005847",
"pos": [
177,
190
],
"name": "blood vessels"
} | {
"id": "C0040300",
"pos": [
17,
24
],
"name": "tissues"
} | 0NA |
Progesterone serum levels were assessed on days 20 - 24 of the cycle after surgical treatment . | {
"id": "C0033308",
"pos": [
0,
12
],
"name": "Progesterone"
} | {
"id": "C0543467",
"pos": [
75,
93
],
"name": "surgical treatment"
} | 0NA |
There are few cases of invaginated anomalous laminae of the axis in the literature . | {
"id": "C0221224",
"pos": [
23,
34
],
"name": "invaginated"
} | {
"id": "C0004457",
"pos": [
60,
64
],
"name": "axis"
} | 0NA |
Affected individuals often show a unique pattern of cognitive strengths and weaknesses and are at increased risk for a number of other neurodevelopmental conditions , many of which are more common in typical males than typical females ( e.g. , autism and attention-deficit hyperactivity disorder ) . | {
"id": "C0086287",
"pos": [
227,
234
],
"name": "females"
} | {
"id": "C1263846",
"pos": [
255,
295
],
"name": "attention-deficit hyperactivity disorder"
} | 0NA |
Further investigation into the favorable effect of statin use on brachytherapy and radiation therapy in general is warranted , including prospective trials . | {
"id": "C0006098",
"pos": [
65,
78
],
"name": "brachytherapy"
} | {
"id": "C0360714",
"pos": [
51,
57
],
"name": "statin"
} | 0NA |
TBLB at 11 and 13 months after the operation showed the recurrence of pulmonary sarcoidosis in the donor lung . | {
"id": "C0024109",
"pos": [
105,
109
],
"name": "lung"
} | {
"id": "C0036205",
"pos": [
70,
91
],
"name": "pulmonary sarcoidosis"
} | 11finding_site_of |
Five resin cements with different colors and opacities ( Multilink Automix white opaque , Multilink Automix yellow , Nexus3 white opaque , Nexus3 white , Nexus3 yellow ) of 3 thicknesses ( 300 μm , 100 μm , 50 μm ) were sequentially luted to a roughened Ag-Pd alloy foundation restoration block . | {
"id": "C0028778",
"pos": [
289,
294
],
"name": "block"
} | {
"id": "C0029053",
"pos": [
45,
54
],
"name": "opacities"
} | 0NA |
The history of this population in the United States provides insight into the increased incidence of several genetic diseases , most notably maple syrup urine disease ( MSUD ) , Hirschsprung disease ( HSCR ) , and congenital nephrotic syndrome . | {
"id": "C0019247",
"pos": [
109,
125
],
"name": "genetic diseases"
} | {
"id": "C0019569",
"pos": [
178,
198
],
"name": "Hirschsprung disease"
} | 0NA |
Two independent observers assessed medical records for quality of documentation and assigned a diagnosis of likely , possible , unlikely TIA or ischemic stroke , according to prespecified criteria . | {
"id": "C0007787",
"pos": [
137,
140
],
"name": "TIA"
} | {
"id": "C0948008",
"pos": [
144,
159
],
"name": "ischemic stroke"
} | 0NA |
The aim of this study was to investigate the alterations of the mesenteric adipose tissue in two experimental colitis models in mice adapted to obtain moderate colonic inflammation . | {
"id": "C0009368",
"pos": [
160,
167
],
"name": "colonic"
} | {
"id": "C0009319",
"pos": [
110,
117
],
"name": "colitis"
} | 11finding_site_of |
Furthermore , during the baseline condition , men generally exhibited more activation ( lower EEG power values ) throughout all regions of the scalp . | {
"id": "C0012634",
"pos": [
34,
43
],
"name": "condition"
} | {
"id": "C0036270",
"pos": [
143,
148
],
"name": "scalp"
} | 0NA |
The data indicate that , in the reducing in vivo environment , the absence of the intra-domain disulfide bond is not an impediment to correction of antibody folding or to interaction with antigen . | {
"id": "C0185026",
"pos": [
157,
164
],
"name": "folding"
} | {
"id": "C0003241",
"pos": [
148,
156
],
"name": "antibody"
} | 0NA |
High doses of BK can induce vascular contraction in hemorrhagic shock condition , which is endothelium and myoendothelial gap junction dependent . | {
"id": "C0429964",
"pos": [
135,
144
],
"name": "dependent"
} | {
"id": "C0012634",
"pos": [
70,
79
],
"name": "condition"
} | 0NA |
Previously we established that the pressure drop along arteries remained nearly constant during the many-fold increase of blood flow rate . | {
"id": "C0003842",
"pos": [
55,
63
],
"name": "arteries"
} | {
"id": "C0232338",
"pos": [
122,
132
],
"name": "blood flow"
} | 0NA |
It was found that the removal of total solids from cutting and equalization process wastewaters was highest for the 100 ppm dosage of all chemicals used . | {
"id": "C0015252",
"pos": [
22,
29
],
"name": "removal"
} | {
"id": "C0220806",
"pos": [
138,
147
],
"name": "chemicals"
} | 0NA |
IPC can reduce stiffness and subcutaneous tissue thickness of the proximal upper arm in patients with PMLE . | {
"id": "C0446516",
"pos": [
75,
84
],
"name": "upper arm"
} | {
"id": "C0222331",
"pos": [
29,
48
],
"name": "subcutaneous tissue"
} | 0NA |
Stimulation applied to the vagus , glossopharyngeal , cochlear and trigeminal nerves evoked widely spreading depolarization waves with similar spatiotemporal distribution patterns . | {
"id": "C1292856",
"pos": [
0,
11
],
"name": "Stimulation"
} | {
"id": "C0042276",
"pos": [
27,
32
],
"name": "vagus"
} | 0NA |
It has demonstrated efficacy in short-term trials versus placebo , two of which included an active comparator ( olanzapine , quetiapine ) assay arm . | {
"id": "C0171023",
"pos": [
112,
122
],
"name": "olanzapine"
} | {
"id": "C0123091",
"pos": [
125,
135
],
"name": "quetiapine"
} | 0NA |
However , sensitivity to this drug has recently decreased in Thailand , Cambodia and Myanmar , and there is no suitable single alternative drug . | {
"id": "C0013227",
"pos": [
30,
34
],
"name": "drug"
} | {
"id": "C0020517",
"pos": [
10,
21
],
"name": "sensitivity"
} | 0NA |
Trophic factors secreted both from the endocardium and epicardium regulate appropriate growth of the myocardium during cardiac development . | {
"id": "C0027061",
"pos": [
101,
111
],
"name": "myocardium"
} | {
"id": "C0225968",
"pos": [
55,
65
],
"name": "epicardium"
} | 0NA |
Cancer screening is an important component of prevention and early detection in public health and clinical medicine . | {
"id": "C0006826",
"pos": [
0,
6
],
"name": "Cancer"
} | {
"id": "C0199230",
"pos": [
7,
16
],
"name": "screening"
} | 12focus_of |
A visiting anesthesiologist had better avoid explaining anesthesia on the day of operation . | {
"id": "C0002903",
"pos": [
56,
66
],
"name": "anesthesia"
} | {
"id": "C0543467",
"pos": [
81,
90
],
"name": "operation"
} | 0NA |
Suspected adhesions of the bowel can often be documented , and primary or secondary neoplastic processes can be identified and biopsied . | {
"id": "C0001511",
"pos": [
10,
19
],
"name": "adhesions"
} | {
"id": "C0021853",
"pos": [
27,
32
],
"name": "bowel"
} | 0NA |
ET(PT ) and ET(IT ) may represent two expressions within a continuous spectrum of cerebellar dysfunction in relation to the timing of muscle activation during voluntary movements . | {
"id": "C0007765",
"pos": [
82,
92
],
"name": "cerebellar"
} | {
"id": "C0185117",
"pos": [
38,
49
],
"name": "expressions"
} | 0NA |
Myocarditis is defined as an inflammation of the heart muscle and often follows enterovirus infections . | {
"id": "C0021368",
"pos": [
29,
41
],
"name": "inflammation"
} | {
"id": "C0027059",
"pos": [
0,
11
],
"name": "Myocarditis"
} | 3associated_morphology_of |
We have investigated the properties of antidromically identified lamina I neurons in the rat dorsal horn ( in vivo ) after neonatal administration of antibody to nerve growth factor ( anti-NGF ) . | {
"id": "C0003241",
"pos": [
150,
158
],
"name": "antibody"
} | {
"id": "C0228575",
"pos": [
93,
104
],
"name": "dorsal horn"
} | 0NA |
All 4 temporal bones showed developmental failures of the stapes , and 3 of them had malposition of the tympanic portion of the facial nerve . | {
"id": "C0015462",
"pos": [
128,
140
],
"name": "facial nerve"
} | {
"id": "C0039484",
"pos": [
6,
20
],
"name": "temporal bones"
} | 0NA |
Six of 14 patients with breast cancer demonstrated deficiency of suppressor cell activity against proliferation of autologous lymphocytes to PHA . | {
"id": "C0334094",
"pos": [
98,
111
],
"name": "proliferation"
} | {
"id": "C0030779",
"pos": [
141,
144
],
"name": "PHA"
} | 0NA |
This study focuses the role of heart rate on cardiac output ( CO ) at rest and during walk test in patients with dual-chamber pacemaker and depressed or normal left ventricular ( LV ) function . | {
"id": "C0344315",
"pos": [
140,
149
],
"name": "depressed"
} | {
"id": "C0018810",
"pos": [
31,
41
],
"name": "heart rate"
} | 0NA |
Auto-antibodies encephalitis and ADEM , although not infectious diseases , can mimick viral encephalitis and should be included in the differential diagnosis of encephalitis patients . | {
"id": "C0014038",
"pos": [
161,
173
],
"name": "encephalitis"
} | {
"id": "C0009450",
"pos": [
53,
72
],
"name": "infectious diseases"
} | 0NA |
Arterial hypertension , dyslipidaemia and diabetes mellitus were significantly more prevalent in the patients with RVO than in the controls ( 73.6 vs. 50 % , 64.6 vs. 48.6 % and 27.8 vs. 12.3 % , respectively ) . | {
"id": "C0011849",
"pos": [
42,
59
],
"name": "diabetes mellitus"
} | {
"id": "C0020538",
"pos": [
0,
21
],
"name": "Arterial hypertension"
} | 0NA |
Erectile dysfunction ( ED ) is a disorder with a high prevalence that increases with age . | {
"id": "C0242350",
"pos": [
0,
20
],
"name": "Erectile dysfunction"
} | {
"id": "C0012634",
"pos": [
33,
41
],
"name": "disorder"
} | 0NA |
The accuracy of preoperative MRI in predicting ACL rupture and meniscus pathology was also compared . | {
"id": "C0024485",
"pos": [
29,
32
],
"name": "MRI"
} | {
"id": "C0224498",
"pos": [
63,
71
],
"name": "meniscus"
} | 0NA |
One mechanism relates to its weak affinity for mu-opioid receptors ( 6,000-fold less than morphine , 100-fold less than d-propoxyphene , 10-fold less than codeine , and equivalent to dextromethorphan ) . | {
"id": "C0011816",
"pos": [
183,
199
],
"name": "dextromethorphan"
} | {
"id": "C0033493",
"pos": [
120,
134
],
"name": "d-propoxyphene"
} | 0NA |
The 22q11.2 DS syndrome has a variable phenotype associated with other genetic syndromes , birth defects in many tissues and organs , and a high rate of psychiatric disorders , particularly schizophrenia . | {
"id": "C0040300",
"pos": [
113,
120
],
"name": "tissues"
} | {
"id": "C0000768",
"pos": [
91,
104
],
"name": "birth defects"
} | 0NA |
Ischemic stroke significantly increased the area under the plasma pentobarbital concentration-time curve , but dexamethasone prevented this increase . | {
"id": "C0032105",
"pos": [
59,
65
],
"name": "plasma"
} | {
"id": "C0948008",
"pos": [
0,
15
],
"name": "Ischemic stroke"
} | 0NA |
The variables studied were sex , age , weight , height , family history of hypertension , engaging in physical exercise , smoking , and consuming alcohol . | {
"id": "C0020538",
"pos": [
75,
87
],
"name": "hypertension"
} | {
"id": "C0425152",
"pos": [
90,
98
],
"name": "engaging"
} | 0NA |
He was treated with abdominoperineal resection of the pouch and rectum , followed by chemotherapy . | {
"id": "C0034896",
"pos": [
64,
70
],
"name": "rectum"
} | {
"id": "C2004459",
"pos": [
20,
46
],
"name": "abdominoperineal resection"
} | 9direct_procedure_site_of |
This study determined the neuropsychological and emotional correlates of Novelty Seeking , Harm Avoidance and two other personality traits that are often considered in PD , i.e. Reward Dependence and Persistence . | {
"id": "C0546816",
"pos": [
200,
211
],
"name": "Persistence"
} | {
"id": "C0013987",
"pos": [
49,
58
],
"name": "emotional"
} | 0NA |
The purpose of this study was to detect the expression levels of geminin and cdt1 in peripheral blood and bone marrow from patients with newly diagnosed acute leukemia ( AL ) , and further explore effects of them in the pathogenesis of AL . | {
"id": "C0005953",
"pos": [
106,
117
],
"name": "bone marrow"
} | {
"id": "C0085669",
"pos": [
153,
167
],
"name": "acute leukemia"
} | 11finding_site_of |
The results indicated that physicians are generally aware of nutritional information related to common prevalent topics related to adequate intake level of calcium for adults , the protective effect of potassium in hypertension , the preventive action of fruits and vegetables against cancer , toxic vitamins if consumed excessively , and the nutrients associated with the prevention of neural tube defects , scoring between 70 - 90 % . | {
"id": "C0006675",
"pos": [
156,
163
],
"name": "calcium"
} | {
"id": "C0032821",
"pos": [
202,
211
],
"name": "potassium"
} | 0NA |
In recent years major progress has been made in identifying the molecular mechanisms by which UV radiation modulates the immune system of the skin . | {
"id": "C0020962",
"pos": [
121,
134
],
"name": "immune system"
} | {
"id": "C0444099",
"pos": [
142,
146
],
"name": "skin"
} | 0NA |
Orofacial clefts , including cleft lip with or without palate ( CL/P ) and cleft palate ( CP ) , are one of the most common congenital malformations in Asian populations , where the rate of incidence is higher than in European or other racial groups . | {
"id": "C0700374",
"pos": [
55,
61
],
"name": "palate"
} | {
"id": "C0008925",
"pos": [
75,
87
],
"name": "cleft palate"
} | 11finding_site_of |
Acquisition of the discriminated taste aversion , as measured by the differential effects on saccharin drinking between drug and saline trials , required only two to three pairings of either drug stimulus with LiCl injections . | {
"id": "C0013227",
"pos": [
120,
124
],
"name": "drug"
} | {
"id": "C0021485",
"pos": [
215,
225
],
"name": "injections"
} | 10direct_substance_of |
Differential item functioning relevant to the time since stroke was detected for 2 tasks . | {
"id": "C0442726",
"pos": [
68,
76
],
"name": "detected"
} | {
"id": "C0038454",
"pos": [
57,
63
],
"name": "stroke"
} | 0NA |
Thus , both NMDA receptor activation and calcium are involved in the damage due to oxygen and glucose deprivation in the slice . | {
"id": "C0010957",
"pos": [
69,
75
],
"name": "damage"
} | {
"id": "C0006675",
"pos": [
41,
48
],
"name": "calcium"
} | 0NA |
Patients at greater risk of intraoperative complications were those with a higher BMI , a greater number of previous open abdominal surgeries , or severe adhesions noted at the time of procedure . | {
"id": "C0205082",
"pos": [
147,
153
],
"name": "severe"
} | {
"id": "C0184661",
"pos": [
185,
194
],
"name": "procedure"
} | 0NA |
Results show that treatment of LOH patients with this Tongkat ali extract significantly ( P < 0.0001 ) improved the AMS score as well as the serum testosterone concentration . | {
"id": "C0039601",
"pos": [
147,
159
],
"name": "testosterone"
} | {
"id": "C1860224",
"pos": [
116,
119
],
"name": "AMS"
} | 0NA |
The relative order of potency for the M3 muscarinic receptor ( highest to lowest ) was pancuronium , atracurium , pipecuronium , rocuronium , mivacurium , gallamine , succinylcholine , and doxacurium . | {
"id": "C0038627",
"pos": [
167,
182
],
"name": "succinylcholine"
} | {
"id": "C0004234",
"pos": [
101,
111
],
"name": "atracurium"
} | 0NA |
A local excision of the lump was performed and a diagnosis of cystic lymphangioma was made . | {
"id": "C0577559",
"pos": [
24,
28
],
"name": "lump"
} | {
"id": "C0206620",
"pos": [
62,
81
],
"name": "cystic lymphangioma"
} | 0NA |
Our study highlights the importance of biochemical investigations in understanding the proximate mechanisms by which temperature affects embryonic development . | {
"id": "C0005903",
"pos": [
117,
128
],
"name": "temperature"
} | {
"id": "C1261322",
"pos": [
51,
65
],
"name": "investigations"
} | 0NA |
From 1998 to 2011 , 193 consecutive patients ( 141 females , 52 males ; mean age = 52.9 years ) were referred to our institution for presurgical embolization of an extra-axial tumor ( meningiomas : n = 178 ; solitary fibrous tumors : n = 3 ; other : n = 12 ) . | {
"id": "C0013931",
"pos": [
145,
157
],
"name": "embolization"
} | {
"id": "C0086582",
"pos": [
64,
69
],
"name": "males"
} | 0NA |
It appeared that thrombin generation by factor VIIa infusion had occurred mainly via the intrinsic , factor VIII-dependent pathway . | {
"id": "C0574032",
"pos": [
52,
60
],
"name": "infusion"
} | {
"id": "C0015505",
"pos": [
40,
51
],
"name": "factor VIIa"
} | 0NA |
In conclusion , according to the data of the present study , ThPOK may be considered a central regulator of the earliest events in the immune system during colorectal cancer development , decreasing the immune response against cancer cells . | {
"id": "C0020962",
"pos": [
135,
148
],
"name": "immune system"
} | {
"id": "C0301872",
"pos": [
203,
218
],
"name": "immune response"
} | 0NA |
To examine the influence of different surgical procedures on clinical outcome in patients undergoing aortic root replacement for ascending aorta aneurysm ( AAA ) with or without concomitant aortic valve regurgitation ( AR ) . | {
"id": "C0543467",
"pos": [
38,
57
],
"name": "surgical procedures"
} | {
"id": "C0003486",
"pos": [
156,
159
],
"name": "AAA"
} | 0NA |
They also indicate that , T. californicus populations can maintain fitness over a wide range of daily variability but are more sensitive to small changes in the mean temperature . | {
"id": "C0020517",
"pos": [
127,
136
],
"name": "sensitive"
} | {
"id": "C0005903",
"pos": [
166,
177
],
"name": "temperature"
} | 0NA |
We used either the synthetic estrogen R2858 ( moxestrol ) or estradiol-17 beta to characterize estrogen receptors in cytoplasmic ( R2858 ) and nuclear ( estradiol-17 beta ) preparations from rat aorta and myocardium . | {
"id": "C0003483",
"pos": [
195,
200
],
"name": "aorta"
} | {
"id": "C0027061",
"pos": [
205,
215
],
"name": "myocardium"
} | 0NA |
To decompress the swollen brain rapidly , transcortical approach seems to be more suitable than transsylvian approach . | {
"id": "C0006104",
"pos": [
26,
31
],
"name": "brain"
} | {
"id": "C0038999",
"pos": [
18,
25
],
"name": "swollen"
} | 0NA |
Drug must enter the brain by crossing from the blood into the brain tissue , called a transvascular route ( TVR ) . | {
"id": "C0005767",
"pos": [
47,
52
],
"name": "blood"
} | {
"id": "C0006104",
"pos": [
20,
25
],
"name": "brain"
} | 0NA |
This would clearly elevate the infant 's DHA intake and might have implications for brain and retinal development . | {
"id": "C0006104",
"pos": [
84,
89
],
"name": "brain"
} | {
"id": "C0035298",
"pos": [
94,
101
],
"name": "retinal"
} | 0NA |
MRI may also provide a better classification of syringomyelia . | {
"id": "C0024485",
"pos": [
0,
3
],
"name": "MRI"
} | {
"id": "C0039144",
"pos": [
48,
61
],
"name": "syringomyelia"
} | 0NA |
Analogue internal standards for fluoroquinolones , sulfonamides , trimethoprim , beta-lactams ( penicillins and cephalosporins ) , nitroimidazoles and tetracyclines were successfully used for calibration and shown to generally improve precision compared to external calibration . | {
"id": "C0041041",
"pos": [
66,
78
],
"name": "trimethoprim"
} | {
"id": "C0038760",
"pos": [
51,
63
],
"name": "sulfonamides"
} | 0NA |
We performed experiments in the absence of light and feeding-time cues to test which core clock genes are controlled by CREM/ICER in the liver and adrenal gland . | {
"id": "C0001625",
"pos": [
147,
160
],
"name": "adrenal gland"
} | {
"id": "C0022885",
"pos": [
74,
78
],
"name": "test"
} | 0NA |
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