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22 classes
Of the 1667 acute stroke patients included , 213 ( 12.8 % ) had diabetes mellitus .
{ "id": "C0011849", "pos": [ 64, 81 ], "name": "diabetes mellitus" }
{ "id": "C0751956", "pos": [ 12, 24 ], "name": "acute stroke" }
0NA
Fluorescence induced by FNa , 5-ALA , AO , AF , CV , and SR101 and detected with the confocal endomicroscope allowed interpretation of histological features .
{ "id": "C0442726", "pos": [ 67, 75 ], "name": "detected" }
{ "id": "C0002563", "pos": [ 30, 35 ], "name": "5-ALA" }
0NA
Several proteins identified as substrates of sirtuin 3 and 5 and active in intermediary and ketone metabolism were hyperacetylated in liver and brown fat mitochondria after both HFD and fasting regimens .
{ "id": "C0023884", "pos": [ 134, 139 ], "name": "liver" }
{ "id": "C0006298", "pos": [ 144, 153 ], "name": "brown fat" }
0NA
Here we aimed to investigate the exposomic characteristics of plasma metals among Mn-exposed workers and explore the potential biomarkers of Mn exposure in the blood pool .
{ "id": "C0025552", "pos": [ 69, 75 ], "name": "metals" }
{ "id": "C0274281", "pos": [ 144, 152 ], "name": "exposure" }
0NA
Assessment of the preference of sheep for fresh , dried or ensiled forms of mucuna ( Mucuna pruriens var utilis ) forage was followed by investigations into the effect of supplementing straw-based diets with the forage .
{ "id": "C1261322", "pos": [ 137, 151 ], "name": "investigations" }
{ "id": "C0031809", "pos": [ 0, 10 ], "name": "Assessment" }
17method_of
Importantly , full characterization of the latter is a prerequisite to rationalize modulation of this process by lipids , toxins , drugs , and genetic mutations .
{ "id": "C0013227", "pos": [ 131, 136 ], "name": "drugs" }
{ "id": "C0040549", "pos": [ 122, 128 ], "name": "toxins" }
0NA
For this purpose , the CD44+/CD24-/low MCF-7 breast cancer stem/progenitor cell population was isolated and treated with doxorubicin or tamoxifen and evaluated for their response to growth , autophagy and apoptosis .
{ "id": "C0039286", "pos": [ 136, 145 ], "name": "tamoxifen" }
{ "id": "C0013089", "pos": [ 121, 132 ], "name": "doxorubicin" }
0NA
After a complete coagulation profile examination , deficiencies of protein C and anti-thrombin III were found and were considered as the main cause of the disease .
{ "id": "C0031809", "pos": [ 37, 48 ], "name": "examination" }
{ "id": "C0012634", "pos": [ 155, 162 ], "name": "disease" }
0NA
These reconstructions may be performed with either an endarterectomy or bypass technique .
{ "id": "C0524865", "pos": [ 6, 21 ], "name": "reconstructions" }
{ "id": "C0014098", "pos": [ 54, 68 ], "name": "endarterectomy" }
0NA
Non-classic lipoid CAH is a newly described variant caused by StAR mutations that retain 10 - 25 % of function , and characterized by onset of glucocorticoid deficiency after 2 years of age , and mild defects in mineralocorticoid and sex steroid synthesis .
{ "id": "C0038317", "pos": [ 238, 245 ], "name": "steroid" }
{ "id": "C0026160", "pos": [ 212, 229 ], "name": "mineralocorticoid" }
0NA
The trailblazing research on sleep mechanisms and petit mal epilepsy , conducted during the period from 1940 through 1970 , illuminated the brain substrate for normal consciousness and attention , as well as their disorders .
{ "id": "C0006104", "pos": [ 140, 145 ], "name": "brain" }
{ "id": "C0014553", "pos": [ 50, 68 ], "name": "petit mal epilepsy" }
11finding_site_of
Twelve surgical specimens from radical vulvectomy and bilateral groin dissection were examined by xeroradiography to identify lymph nodes .
{ "id": "C0024204", "pos": [ 126, 137 ], "name": "lymph nodes" }
{ "id": "C0177252", "pos": [ 31, 49 ], "name": "radical vulvectomy" }
0NA
Prospective clinical trials are required to test the effect of higher relative dose intensity for doxorubicin and cyclophosphamide added to platinum in advanced ovarian cancer .
{ "id": "C0032207", "pos": [ 140, 148 ], "name": "platinum" }
{ "id": "C0010583", "pos": [ 114, 130 ], "name": "cyclophosphamide" }
0NA
There is little doubt that PTCA procedures may provide successful myocardial revascularization .
{ "id": "C2936173", "pos": [ 27, 31 ], "name": "PTCA" }
{ "id": "C0027056", "pos": [ 66, 94 ], "name": "myocardial revascularization" }
0NA
The use of Losartan , an Ang II type 1 receptor ( AT1R ) antagonist has proven to be effective reducing hypertension and renal damage ; however , the mechanism by which AT1R blockade reduced kidney injury and normalizes blood pressure in this experimental model is still complete unknown .
{ "id": "C0020538", "pos": [ 104, 116 ], "name": "hypertension" }
{ "id": "C0005823", "pos": [ 220, 234 ], "name": "blood pressure" }
15interprets
Severe ischaemic complications in neonates following arterial catheterisation were rare events , but could cause devastating damage .
{ "id": "C0010957", "pos": [ 125, 131 ], "name": "damage" }
{ "id": "C0007431", "pos": [ 53, 77 ], "name": "arterial catheterisation" }
0NA
We therefore conclude that benign enhancement of cardiac proteasome proteolytic function can be achieved by CR-PA28αOE and that PFI plays a major pathogenic role in cardiac proteinopathy and myocardial I/R injury .
{ "id": "C0018787", "pos": [ 49, 56 ], "name": "cardiac" }
{ "id": "C1627358", "pos": [ 34, 45 ], "name": "enhancement" }
0NA
The study included 233 physicians , of varying specialties , assessed by the University of California , San Diego Physician Assessment and Clinical Education Program ( PACE ) , between 2008 and 2012 , who completed the Post-Licensure Assessment System Mechanisms of Disease ( MoD ) examination .
{ "id": "C0031809", "pos": [ 282, 293 ], "name": "examination" }
{ "id": "C0012634", "pos": [ 266, 273 ], "name": "Disease" }
0NA
Some proteins , mutated on " abnormally " regulated are inducers of diseases , such as cancers or degenerative diseases .
{ "id": "C0006826", "pos": [ 87, 94 ], "name": "cancers" }
{ "id": "C0012634", "pos": [ 68, 76 ], "name": "diseases" }
0NA
The prescence of CSF infection could be diagnosed earlier and during a longer period when the leucocyte count or polymerase chain reaction were used in comparison with virus isolation in whole blood ( P < 0.05 ) .
{ "id": "C0009450", "pos": [ 21, 30 ], "name": "infection" }
{ "id": "C0204727", "pos": [ 174, 183 ], "name": "isolation" }
12focus_of
The prevalence of fever ( malaria ) was significantly reduced after the intervention ( p = 0.008 ) .
{ "id": "C0024530", "pos": [ 26, 33 ], "name": "malaria" }
{ "id": "C0184661", "pos": [ 72, 84 ], "name": "intervention" }
0NA
The new hand injector allows powerful injections to be performed through No. 8 or 9 French guiding catheters with little strain on the operator 's hands .
{ "id": "C0021485", "pos": [ 38, 48 ], "name": "injections" }
{ "id": "C0085590", "pos": [ 99, 108 ], "name": "catheters" }
0NA
Clomiphene citrate , letrozole , timed intercourse , IUI , gonadotropins , IVF , and IVF-intracytoplasmic sperm injection .
{ "id": "C0246421", "pos": [ 21, 30 ], "name": "letrozole" }
{ "id": "C0021485", "pos": [ 112, 121 ], "name": "injection" }
0NA
Mean time to itch relief ( TR ) defined as the time to reach a 30 % decrease in the highest VAS value recorded was assessed , as well as TR-baseline , colorimetry and planimetric morphometry of the reaction .
{ "id": "C0564405", "pos": [ 18, 24 ], "name": "relief" }
{ "id": "C0033774", "pos": [ 13, 17 ], "name": "itch" }
0NA
Infection with live , but not UV-inactivated , C. trachomatis induced a significant increase in levels of vascular cell adhesion molecule-1 and the mucosal addressin cell adhesion molecule-1 but not of other adhesion molecules .
{ "id": "C0001511", "pos": [ 208, 216 ], "name": "adhesion" }
{ "id": "C0009450", "pos": [ 0, 9 ], "name": "Infection" }
0NA
There was no specific binding of the avidin-biotin complex to rat intestinal mucosa plasma membrane .
{ "id": "C0021853", "pos": [ 66, 76 ], "name": "intestinal" }
{ "id": "C0026724", "pos": [ 77, 83 ], "name": "mucosa" }
0NA
The review article discusses the antidepressant potential of some important polyphenols such as amentoflavone , apigenin , chlorogenic acid , curcumin , ferulic acid , hesperidin , rutin , quercetin , naringenin , resveratrol , ellagic acid , nobiletin and proanthocyanidins .
{ "id": "C0003289", "pos": [ 33, 47 ], "name": "antidepressant" }
{ "id": "C0034392", "pos": [ 189, 198 ], "name": "quercetin" }
0NA
This retrospective cohort study included all patients presenting to a single institution over a 14-month period who had undergone a dedicated musculoskeletal CT pelvis along with a standardized anteroposterior ( AP ) pelvis radiograph .
{ "id": "C0030797", "pos": [ 161, 167 ], "name": "pelvis" }
{ "id": "C0025344", "pos": [ 105, 111 ], "name": "period" }
0NA
Changes in soft tissue clinical outcomes did not show significant differences between the treatments .
{ "id": "C0225317", "pos": [ 11, 22 ], "name": "soft tissue" }
{ "id": "C0087111", "pos": [ 90, 100 ], "name": "treatments" }
0NA
Avulsion amputations of the thumb are generally thought to have a worse prognosis after replantation than other amputations .
{ "id": "C0035139", "pos": [ 88, 100 ], "name": "replantation" }
{ "id": "C0002688", "pos": [ 112, 123 ], "name": "amputations" }
0NA
Qnr blocked inhibition by synthetic compounds with somewhat quinolone-like structure that target the GyrA subunit , such as the 2-pyridone ABT-719 , the quinazoline-2,4-dione PD 0305970 , and the spiropyrimidinetrione pyrazinyl-alkynyl-tetrahydroquinoline ( PAT ) , indicating that Qnr is not strictly quinolone specific , but Qnr did not protect against GyrA-targeting simocyclinone D8 despite evidence that both simocyclinone D8 and Qnr affect DNA binding to gyrase .
{ "id": "C0028778", "pos": [ 4, 11 ], "name": "blocked" }
{ "id": "C0030587", "pos": [ 258, 261 ], "name": "PAT" }
0NA
This review will examine the role of PKC activity in stroke .
{ "id": "C0033634", "pos": [ 37, 40 ], "name": "PKC" }
{ "id": "C0038454", "pos": [ 53, 59 ], "name": "stroke" }
0NA
The inhibition by ATP and adenosine of field stimulation-induced contractions in the rat prostate was antagonized by 8-phenyltheophylline ( 10 microM ) , but not by suramin ( 100 microM ) and only slightly by reactive blue 2 ( 5 microM ) .
{ "id": "C0001480", "pos": [ 18, 21 ], "name": "ATP" }
{ "id": "C0001443", "pos": [ 26, 35 ], "name": "adenosine" }
16is_modification_of
These findings indicate that Acti4 provides good estimates of time spent in different activity types during semi-standardised conditions , and for sitting , standing and walking during non-standardised conditions with normal level of movement complexity .
{ "id": "C0277814", "pos": [ 147, 154 ], "name": "sitting" }
{ "id": "C0026649", "pos": [ 234, 242 ], "name": "movement" }
0NA
This disease should now be included in the differential diagnosis of pituitary disorders , especially in females presenting with pituitary enlargement , particularly if symptoms occur in temporal relationship to pregnancy .
{ "id": "C0012634", "pos": [ 5, 12 ], "name": "disease" }
{ "id": "C0032002", "pos": [ 69, 88 ], "name": "pituitary disorders" }
0NA
After that two recurrences , both of which were accompanied with loss of depth of the anterior chamber , we found during a follow-up period of two years .
{ "id": "C0003151", "pos": [ 86, 102 ], "name": "anterior chamber" }
{ "id": "C0025344", "pos": [ 133, 139 ], "name": "period" }
0NA
The top three cited impediments to widespread clinical use of morphine for cancer pain were : ( 1 ) lack of professional knowledge and training ; ( 2 ) fear of opioid addiction ; and ( 3 ) physicians ' personal preferences to select other drugs .
{ "id": "C0013227", "pos": [ 239, 244 ], "name": "drugs" }
{ "id": "C0026549", "pos": [ 62, 70 ], "name": "morphine" }
0NA
One patient ( 2 eyes ) with panuveitis also had bilateral exudative retinal detachment and chronic angle closure glaucoma .
{ "id": "C0015392", "pos": [ 16, 20 ], "name": "eyes" }
{ "id": "C0030343", "pos": [ 28, 38 ], "name": "panuveitis" }
0NA
Maximal oxygen consumption , heart rate , stroke volume , cardiac output and arterial-venous O2 difference were unchanged after 6 weeks of treatment .
{ "id": "C0038454", "pos": [ 42, 48 ], "name": "stroke" }
{ "id": "C0018810", "pos": [ 29, 39 ], "name": "heart rate" }
0NA
Two epikeratoplasty lenticules ( Epi-L ) with keratoconus host corneas ( Epi-H ) were removed by penetrating keratoplasty because of poor visual acuity although they were clinically clear .
{ "id": "C0010042", "pos": [ 109, 121 ], "name": "keratoplasty" }
{ "id": "C0042812", "pos": [ 138, 151 ], "name": "visual acuity" }
0NA
It is remarkable that three of the highest effect sizes of physical activity appeared on parameters thought to be under tight homeostatic control ( i. e. , glucose , calcium , and magnesium ) .
{ "id": "C0024467", "pos": [ 180, 189 ], "name": "magnesium" }
{ "id": "C0006675", "pos": [ 166, 173 ], "name": "calcium" }
0NA
In contrast , fracture morphology was the most common factor ( 67   % ) described by surgeons recommending replacement .
{ "id": "C0016658", "pos": [ 14, 22 ], "name": "fracture" }
{ "id": "C0035139", "pos": [ 107, 118 ], "name": "replacement" }
0NA
The purpose of this study was to identify the influence of vitamin D status ( insufficient vs. sufficient ) on circulating cytokines and skeletal muscle strength after muscular injury .
{ "id": "C0242692", "pos": [ 137, 152 ], "name": "skeletal muscle" }
{ "id": "C0410256", "pos": [ 168, 183 ], "name": "muscular injury" }
0NA
The present study was undertaken in order to find out if a nonproteic neurotrophic factor like n-hexacosanol may be able to reduce the neuronal damages induced by the excitatory amino acid , kainic acid .
{ "id": "C0010957", "pos": [ 144, 151 ], "name": "damages" }
{ "id": "C0002520", "pos": [ 178, 188 ], "name": "amino acid" }
0NA
Initially , an optimum proportion of the two drugs , 3.5 mg/kg nefopam ( N ) + 60 mg/kg acetaminophen ( A ) , was determined by orthogonal array design based on writhing response number .
{ "id": "C0000970", "pos": [ 88, 101 ], "name": "acetaminophen" }
{ "id": "C0013227", "pos": [ 45, 50 ], "name": "drugs" }
0NA
The hippocampus is considered as the main radiosensitive brain structure responsible for postradiotherapy cognitive decline .
{ "id": "C0006104", "pos": [ 57, 72 ], "name": "brain structure" }
{ "id": "C0019564", "pos": [ 4, 15 ], "name": "hippocampus" }
0NA
A 61-years old man , who had undergone gastric resection 30 years before , was admitted at emergency room with severe abdominal pain in acute onset , nausea and vomiting .
{ "id": "C0205082", "pos": [ 111, 117 ], "name": "severe" }
{ "id": "C0000737", "pos": [ 118, 132 ], "name": "abdominal pain" }
0NA
Biopsy or subtotal resection followed by radiation for intramedullary astrocytomas of the spinal cord offer palliation but not cure .
{ "id": "C0037925", "pos": [ 90, 101 ], "name": "spinal cord" }
{ "id": "C0005558", "pos": [ 0, 6 ], "name": "Biopsy" }
0NA
In particular , it describes how low modulus , good adhesion , and absolute extensibility prior to fracture enable robust performance , along with mechanical " imperceptibility " if worn on the skin .
{ "id": "C0001511", "pos": [ 52, 60 ], "name": "adhesion" }
{ "id": "C0444099", "pos": [ 194, 198 ], "name": "skin" }
0NA
Lesions with hinge motion ( OR 8.90 , 95 % CI 3.84 to 20.6 , P<0.001 ) , tortuosity ( OR 4.16 , 95 % CI 1.75 to 9.88 , P=0.001 ) , and overlapping stents ( OR 2.41 , 95 % CI 0.95 to 6.10 , P=0.06 ) were predictors of SF .
{ "id": "C0221198", "pos": [ 0, 7 ], "name": "Lesions" }
{ "id": "C0038257", "pos": [ 147, 153 ], "name": "stents" }
0NA
Inhibition of mural cell recruitment to the dorsal aorta through disruption of pdgfr signaling leads to a reduced vascular basement membrane , which in turn results in enhanced dorsal aorta vessel elasticity and failure to restrict aortic diameter .
{ "id": "C0003483", "pos": [ 232, 238 ], "name": "aortic" }
{ "id": "C0271510", "pos": [ 25, 36 ], "name": "recruitment" }
0NA
The present study examined whether there is any obvious correlation between the density of lipofuscin-containing neurons and the spontaneous neuronal action potentials ( Multiple Unit Activity , MUA ) in the parietal cortex of the aging rat brain .
{ "id": "C0006104", "pos": [ 241, 246 ], "name": "brain" }
{ "id": "C0030560", "pos": [ 208, 223 ], "name": "parietal cortex" }
0NA
The present results may suggest that there is a difference in nucleotide metabolism between untreated and relapsed leukemic cells , and nucleotide profiles provide more accurate information of leukemia chemotherapy .
{ "id": "C0013216", "pos": [ 202, 214 ], "name": "chemotherapy" }
{ "id": "C0023418", "pos": [ 193, 201 ], "name": "leukemia" }
0NA
The OCT catheter was inserted into the working channel of the bronchoscope for evaluation of the bronchial lumen .
{ "id": "C0085590", "pos": [ 8, 16 ], "name": "catheter" }
{ "id": "C0179432", "pos": [ 62, 74 ], "name": "bronchoscope" }
0NA
In controls plasma clearance was 415 + /- 24 ml min-1 m-2 ( mean + /- SEM ) , equivalent to a ' first-pass ' extraction by the liver of 85 % .
{ "id": "C0023884", "pos": [ 127, 132 ], "name": "liver" }
{ "id": "C0185115", "pos": [ 109, 119 ], "name": "extraction" }
0NA
The demonstration of DCTs in cyst fluid and the absence of malignant cells confirmed the benign nature of these lesions , allowing conservative and expectant management for these patients .
{ "id": "C0221198", "pos": [ 112, 119 ], "name": "lesions" }
{ "id": "C0700325", "pos": [ 148, 168 ], "name": "expectant management" }
0NA
The intrapetrous facial nerve has the second longest intraosseous course of all cranial nerves , after the mandibular nerve .
{ "id": "C0010268", "pos": [ 80, 94 ], "name": "cranial nerves" }
{ "id": "C0024695", "pos": [ 107, 123 ], "name": "mandibular nerve" }
0NA
The effects of repeated naloxone-precipitated morphine withdrawals on acoustic startle responding were evaluated in experiments that varied either the dose of the opiate antagonist ( 8-day , repeated measures procedure ) or agonist ( 3-day procedure ) .
{ "id": "C0027410", "pos": [ 163, 180 ], "name": "opiate antagonist" }
{ "id": "C0026549", "pos": [ 46, 54 ], "name": "morphine" }
0NA
This case reviews the acute care and rehabilitation course of a 44-year-old right-handed woman after an assault with a pocketknife .
{ "id": "C0004063", "pos": [ 104, 111 ], "name": "assault" }
{ "id": "C0034991", "pos": [ 37, 51 ], "name": "rehabilitation" }
0NA
The results showed that API significantly reduced renal function markers , serum creatinine and urea nitrogen content .
{ "id": "C0041942", "pos": [ 96, 100 ], "name": "urea" }
{ "id": "C0201976", "pos": [ 75, 91 ], "name": "serum creatinine" }
0NA
Although technical advances in non-invasive and minimally invasive approaches to lung and pleural cancer diagnosis and staging have become more widely available and accurate , surgical techniques remain the gold standard in assessing the extent of loco-regional involvement .
{ "id": "C0153494", "pos": [ 90, 104 ], "name": "pleural cancer" }
{ "id": "C0024109", "pos": [ 81, 85 ], "name": "lung" }
0NA
Squamous cell carcinoma of the colon is a distinctly rare entity .
{ "id": "C0009368", "pos": [ 31, 36 ], "name": "colon" }
{ "id": "C0007137", "pos": [ 0, 23 ], "name": "Squamous cell carcinoma" }
0NA
Preoperative sleep monitoring should be routinely conducted to ensure early diagnosis of OSAHS and SH , and patients with GHPA should be advised to control their body weight to lower the mortality associated with the respiratory system .
{ "id": "C0035237", "pos": [ 217, 235 ], "name": "respiratory system" }
{ "id": "C0520679", "pos": [ 89, 94 ], "name": "OSAHS" }
11finding_site_of
There was one procedure related stroke and one intraprocedural death .
{ "id": "C0184661", "pos": [ 14, 23 ], "name": "procedure" }
{ "id": "C0038454", "pos": [ 32, 38 ], "name": "stroke" }
0NA
Selective covalent inhibition of kinases by targeting poorly conserved cysteines has proven highly fruitful to date in the development of chemical probes and approved drugs .
{ "id": "C0013227", "pos": [ 167, 172 ], "name": "drugs" }
{ "id": "C0010654", "pos": [ 71, 80 ], "name": "cysteines" }
0NA
To evaluate the cephalometric changes in skeletal , dentoalveolar and soft tissue variables induced by Clark 's Twin Block ( CTB ) in Class II , Division 1 malocclusion patients and to compare these changes in different cervical vertebral maturation stages .
{ "id": "C0225317", "pos": [ 70, 81 ], "name": "soft tissue" }
{ "id": "C0027530", "pos": [ 220, 228 ], "name": "cervical" }
0NA
Overexpression of dominant negative RARalpha was induced by Dox in neonatal lungs from d 1 - 21 after birth , a critical period for alveolar maturation .
{ "id": "C0205160", "pos": [ 27, 35 ], "name": "negative" }
{ "id": "C0005615", "pos": [ 102, 107 ], "name": "birth" }
0NA
90 % of the disorders of the body also manifest at the level of the oral cavity , which means that the dentist can draw the attention of a certain health problem .
{ "id": "C0226896", "pos": [ 68, 79 ], "name": "oral cavity" }
{ "id": "C0012634", "pos": [ 12, 21 ], "name": "disorders" }
0NA
Histologic sections of 234 eyes removed for choroidal or ciliary body melanoma were studied for the presence of microcirculation patterns .
{ "id": "C0015392", "pos": [ 27, 31 ], "name": "eyes" }
{ "id": "C0346379", "pos": [ 57, 78 ], "name": "ciliary body melanoma" }
0NA
To strengthen the immune system might help to control or even to eradicate malignant tumors .
{ "id": "C0020962", "pos": [ 18, 31 ], "name": "immune system" }
{ "id": "C0006826", "pos": [ 75, 91 ], "name": "malignant tumors" }
0NA
All the above data are valuable for the development of prediction models and for decision making in order to achieve better timing of treatments .
{ "id": "C0087111", "pos": [ 134, 144 ], "name": "treatments" }
{ "id": "C0011109", "pos": [ 81, 96 ], "name": "decision making" }
0NA
Stent placement occurred an average of 5.6 months after transplantation .
{ "id": "C0038257", "pos": [ 0, 5 ], "name": "Stent" }
{ "id": "C0040732", "pos": [ 56, 71 ], "name": "transplantation" }
0NA
The identification of adult stem cells in the pituitary raised the question if tumor-initiating cells and Hh signaling are involved in pituitary adenoma formation .
{ "id": "C0032005", "pos": [ 46, 55 ], "name": "pituitary" }
{ "id": "C0032000", "pos": [ 135, 152 ], "name": "pituitary adenoma" }
11finding_site_of
Emphasis was placed on the prevalence of total blindness and visual acuity of 20/200 or worse in this group of patients .
{ "id": "C1879328", "pos": [ 41, 56 ], "name": "total blindness" }
{ "id": "C0042812", "pos": [ 61, 74 ], "name": "visual acuity" }
0NA
Ossifying fibromyxoid tumor ( OFMT ) is a rare tumor of unknown histogenesis .
{ "id": "C0027651", "pos": [ 47, 52 ], "name": "tumor" }
{ "id": "C1266128", "pos": [ 0, 27 ], "name": "Ossifying fibromyxoid tumor" }
0NA
Patients with longer depletion time and low baseline levels of IgM were more likely to gain a faster remission , suggesting that the clinical benefit may be linked to suppression of autoreactive plasmablasts .
{ "id": "C0020861", "pos": [ 63, 66 ], "name": "IgM" }
{ "id": "C0221103", "pos": [ 167, 178 ], "name": "suppression" }
0NA
Forty-one of the 50 adenomas ( 82 per cent ) and 48 of the 142 carcinomas were positive for bcl-2 expression .
{ "id": "C1446409", "pos": [ 79, 87 ], "name": "positive" }
{ "id": "C0001430", "pos": [ 20, 28 ], "name": "adenomas" }
0NA
The two methods were equally effective in detecting carcinoma of the colon .
{ "id": "C0009368", "pos": [ 69, 74 ], "name": "colon" }
{ "id": "C0007097", "pos": [ 52, 61 ], "name": "carcinoma" }
0NA
Hemicraniectomy and durotomy have been proposed in many small series to relieve intracranial hypertension and tissue shifts in patients with large hemispheric infarcts , thereby preventing death from herniation .
{ "id": "C0011065", "pos": [ 189, 194 ], "name": "death" }
{ "id": "C0151740", "pos": [ 80, 105 ], "name": "intracranial hypertension" }
0NA
Primary enteric anastomosis was feasible in 3 , Bishop-Koop anastomosis in 2 and an intestinal stoma in two others .
{ "id": "C0559494", "pos": [ 84, 100 ], "name": "intestinal stoma" }
{ "id": "C0399919", "pos": [ 48, 71 ], "name": "Bishop-Koop anastomosis" }
8direct_morphology_of
One sibling , a 19-year-old man , showed in addition to the hyperlipoproteinaemia typical corneal signs of crystalline corneal dystrophy of Schnyder .
{ "id": "C0010031", "pos": [ 90, 97 ], "name": "corneal" }
{ "id": "C0010036", "pos": [ 119, 136 ], "name": "corneal dystrophy" }
11finding_site_of
A histopathologic excision margin of 8 mm or more ( corresponding to a ≥1 cm surgical excision margin ) combined with SLN biopsy ( followed by an immediate completion lymph node dissection if positive ) provided T3 melanoma patients with optimum local , regional , and distant disease control and resulted in enhanced melanoma-specific survival .
{ "id": "C0005558", "pos": [ 122, 128 ], "name": "biopsy" }
{ "id": "C0024203", "pos": [ 167, 188 ], "name": "lymph node dissection" }
0NA
By using cytogenetic and SNP array analysis , we identified a girl with 18p deletion syndrome exhibiting craniofacial anomalies , intellectual disability , and short stature .
{ "id": "C0013336", "pos": [ 160, 173 ], "name": "short stature" }
{ "id": "C3714756", "pos": [ 130, 153 ], "name": "intellectual disability" }
0NA
Two radiologists blindly evaluated all MRI examinations .
{ "id": "C0024485", "pos": [ 39, 42 ], "name": "MRI" }
{ "id": "C0031809", "pos": [ 43, 55 ], "name": "examinations" }
0NA
This study aims to evaluate the efficacy and safety of adding pioglitazone to treatment with metformin ( MF ) and gliclazide in patients with type 2 diabetes mellitus ( DM2 ) who had inadequate glycemic control .
{ "id": "C0071097", "pos": [ 62, 74 ], "name": "pioglitazone" }
{ "id": "C0025598", "pos": [ 93, 102 ], "name": "metformin" }
0NA
Carbamazepine was not eliminated during any season , while ibuprofen , ketoprofen and sertraline were fully eliminated over the studied stretch of river during the summer months .
{ "id": "C0074393", "pos": [ 86, 96 ], "name": "sertraline" }
{ "id": "C0020740", "pos": [ 59, 68 ], "name": "ibuprofen" }
0NA
We tested use of the PET/CT examination in radiotherapy treatment planning of the head and neck carcinoma and it was introduced as a standard clinical practice at our department .
{ "id": "C0031809", "pos": [ 28, 39 ], "name": "examination" }
{ "id": "C1699633", "pos": [ 21, 27 ], "name": "PET/CT" }
0NA
These results suggest that cordycepin has antiviral and antitumor activities against gammaherpesviruses and host cells latently infected with virus .
{ "id": "C0003451", "pos": [ 42, 51 ], "name": "antiviral" }
{ "id": "C0056331", "pos": [ 27, 37 ], "name": "cordycepin" }
0NA
The overall sensitivity of FNA for malignancy was 84 % , and the false-negative rate 9.1 % .
{ "id": "C1510483", "pos": [ 27, 30 ], "name": "FNA" }
{ "id": "C0020517", "pos": [ 12, 23 ], "name": "sensitivity" }
0NA
The contents of L-ENK in pulmonary artery of rat and rabbit measured by radioimmunoassay were respectively 439.18 + /- 30.52 and 29.9 + /- 1.4 ( pg/mg of wct tissue ) .
{ "id": "C0034052", "pos": [ 25, 41 ], "name": "pulmonary artery" }
{ "id": "C0034580", "pos": [ 72, 88 ], "name": "radioimmunoassay" }
0NA
Studies have shown that aging is a significant factor in worsening stroke outcomes .
{ "id": "C0001811", "pos": [ 24, 29 ], "name": "aging" }
{ "id": "C0038454", "pos": [ 67, 73 ], "name": "stroke" }
0NA
Interest in integrating multiparametric magnetic resonance imaging ( MRI ) and magnetic resonance-guided biopsy ( MRGB ) into the diagnostic pathway to reduce overdiagnosis and improve grading is gaining ground , but it remains uncertain whether this image-based strategy is cost-effective .
{ "id": "C0024485", "pos": [ 69, 72 ], "name": "MRI" }
{ "id": "C3898221", "pos": [ 24, 66 ], "name": "multiparametric magnetic resonance imaging" }
17method_of
This study presents an improved leg tracking method using a laser range sensor ( LRS ) for a gait measurement system to evaluate the motor function in walk tests , such as the TUG .
{ "id": "C0023216", "pos": [ 32, 35 ], "name": "leg" }
{ "id": "C1319201", "pos": [ 176, 179 ], "name": "TUG" }
0NA
From these data the ligature tension exerted by vessels up to 3 mm diameter at 150 mm Hg pressure was observed to be less than 5 grams .
{ "id": "C0005847", "pos": [ 48, 55 ], "name": "vessels" }
{ "id": "C0023692", "pos": [ 20, 28 ], "name": "ligature" }
0NA
When only grade B and grade C fistulas were taken into account , the type of stenting has lost its significance but the texture of the remnant pancreas was still associated with ' clinically important ' pancreatic fistula .
{ "id": "C0030274", "pos": [ 143, 151 ], "name": "pancreas" }
{ "id": "C0030290", "pos": [ 203, 221 ], "name": "pancreatic fistula" }
11finding_site_of
L-arginine and D-glucose brought about comparable increases in serum osmolality and similar hemodilution as compared with control saline .
{ "id": "C0229671", "pos": [ 63, 68 ], "name": "serum" }
{ "id": "C0086741", "pos": [ 69, 79 ], "name": "osmolality" }
0NA
Hypertension associated with fibromuscular dysplasia of renal artery is the most common form of secondary hypertension among young patients .
{ "id": "C0020538", "pos": [ 0, 12 ], "name": "Hypertension" }
{ "id": "C0155616", "pos": [ 96, 118 ], "name": "secondary hypertension" }
0NA
A slight predominance of aneuploid tumours in the left colon and rectum was seen .
{ "id": "C0034896", "pos": [ 65, 71 ], "name": "rectum" }
{ "id": "C0227388", "pos": [ 50, 60 ], "name": "left colon" }
0NA
Circulating tumor cells ( CTCs ) in blood are associated with poor survival of patients with breast , prostate , or colon cancer .
{ "id": "C0006141", "pos": [ 93, 99 ], "name": "breast" }
{ "id": "C0033572", "pos": [ 102, 110 ], "name": "prostate" }
0NA
In conclusion , using 50 mg/day elemental zinc for 8 weeks among PCOS women had beneficial effects on alopecia , hirsutism , and plasma MDA levels ; however , it did not affect hormonal profiles , inflammatory cytokines , and other biomarkers of oxidative stress .
{ "id": "C0043481", "pos": [ 42, 46 ], "name": "zinc" }
{ "id": "C0002170", "pos": [ 102, 110 ], "name": "alopecia" }
0NA