text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
The drugs required to permit use of regimens of shorter duration , that may be employed among both PB and MB patients , and that enable fully supervised drug administration may be already in hand , and the necessary clinical trials to confirm efficacy and acceptability should be carried out . | {
"id": "C0013227",
"pos": [
4,
9
],
"name": "drugs"
} | {
"id": "C0150270",
"pos": [
153,
172
],
"name": "drug administration"
} | 0NA |
The use of behavioral scales is an important component in determining efficacy of new drugs in clinical trials for Alzheimer disease ( AD ) . | {
"id": "C0013227",
"pos": [
86,
91
],
"name": "drugs"
} | {
"id": "C0002395",
"pos": [
115,
132
],
"name": "Alzheimer disease"
} | 0NA |
Generation of small and medium-sized aggregates showed a significant positive correlation with OD levels after stimulation with 0.5 or 1.0 muM ADP , or 0.5 or 1.0 micrograms/ml collagen . | {
"id": "C1446409",
"pos": [
69,
77
],
"name": "positive"
} | {
"id": "C1292856",
"pos": [
111,
122
],
"name": "stimulation"
} | 0NA |
Cocaine , because it has a short " high , " creates a need for more frequent injections and therefore increases the likelihood of needle sharing and HIV transmission . | {
"id": "C0027551",
"pos": [
130,
136
],
"name": "needle"
} | {
"id": "C0021485",
"pos": [
77,
87
],
"name": "injections"
} | 0NA |
The purpose of the study was to compare the levels of the intraocular pressure ( NOT ) measured in one eye at the same moment by three different methods : by Goldmann applanation tonometer ( AT ) , non-contact tonometer ( BT ) and Tono-Pen ( TP ) . | {
"id": "C0015392",
"pos": [
103,
106
],
"name": "eye"
} | {
"id": "C1271528",
"pos": [
158,
188
],
"name": "Goldmann applanation tonometer"
} | 0NA |
Motor potentials ( 81.9 % ) somatosensory potential ( PESS ) ( 72.3 % ) and magnetic resonance imaging ( MR ) ( 76.4 % ) were the most abnormal results . | {
"id": "C0205161",
"pos": [
135,
143
],
"name": "abnormal"
} | {
"id": "C0024485",
"pos": [
76,
102
],
"name": "magnetic resonance imaging"
} | 0NA |
Three functions of Sertoli cells were examined with cells from rats aged 13 and 25 days at 34 C , 38 C , and 40 C , namely protein synthesis ( incorporation of amino acids into material precipitated by trichloroacetic acid ) , transport of alpha-aminoisobutyric acid , and production of lactate . | {
"id": "C0002520",
"pos": [
160,
171
],
"name": "amino acids"
} | {
"id": "C0040900",
"pos": [
202,
222
],
"name": "trichloroacetic acid"
} | 0NA |
Examining the causes of atherosclerosis disclosed a pathogenetic association of the immunoregulatory signal CD40-CD40L with the occurrence of arterial atherosclerotic lesions . | {
"id": "C0003842",
"pos": [
142,
150
],
"name": "arterial"
} | {
"id": "C0003850",
"pos": [
24,
39
],
"name": "atherosclerosis"
} | 11finding_site_of |
By combining the use of a unique antibody that selectively immunoprecipitates PrP(Sc ) with glycoform-restrictive antibodies we have developed a rapid assay for vCJD infection that does not require any PK treatment to achieve high levels of specificity in whole human blood , the most challenging potential analyte . | {
"id": "C0003241",
"pos": [
33,
41
],
"name": "antibody"
} | {
"id": "C0009450",
"pos": [
166,
175
],
"name": "infection"
} | 0NA |
In this paper , we will review the current concepts on the recruitment , homing , and activity of T lymphocytes in the lower respiratory tract of patients with sarcoidosis . | {
"id": "C0035237",
"pos": [
125,
142
],
"name": "respiratory tract"
} | {
"id": "C0036202",
"pos": [
160,
171
],
"name": "sarcoidosis"
} | 0NA |
Identification of exercise history patterns that are related to catastrophic scapular fracture will facilitate prevention of racehorse fatalities . | {
"id": "C0199176",
"pos": [
111,
121
],
"name": "prevention"
} | {
"id": "C0159667",
"pos": [
77,
94
],
"name": "scapular fracture"
} | 0NA |
Activation was accomplished by total solubilization of phospholipids and proteins in a Triton X-100/octyl glucoside mixture containing 20 mM octyl glucoside , leading to a threefold stimulation of the ATP synthase activity . | {
"id": "C1292856",
"pos": [
182,
193
],
"name": "stimulation"
} | {
"id": "C0033684",
"pos": [
73,
81
],
"name": "proteins"
} | 0NA |
Intervention strategies have arisen from the studies which demonstrates that stress in families caring for a relative with schizophrenia can be reduced , leading to not only a smaller risk of relapse in the relative with the illness , but also an improvement in the carer 's own mental health status ( Tarrier et al. 1988 ) . | {
"id": "C0221423",
"pos": [
225,
232
],
"name": "illness"
} | {
"id": "C0184661",
"pos": [
0,
12
],
"name": "Intervention"
} | 0NA |
Of the 12 recommendations in the guideline related to history taking , four were not adhered to by the GPs in about 25 % of the patients . | {
"id": "C0199182",
"pos": [
54,
68
],
"name": "history taking"
} | {
"id": "C0272302",
"pos": [
103,
106
],
"name": "GPs"
} | 0NA |
We continued monitoring fetal heart rate during the operation . | {
"id": "C0543467",
"pos": [
52,
61
],
"name": "operation"
} | {
"id": "C0150369",
"pos": [
13,
23
],
"name": "monitoring"
} | 0NA |
In three subjects , the H reflex was evoked in the brachioradialis by stimulation of the radial nerve during performance of the same tasks . | {
"id": "C1292856",
"pos": [
70,
81
],
"name": "stimulation"
} | {
"id": "C0224264",
"pos": [
51,
66
],
"name": "brachioradialis"
} | 0NA |
Abnormalities in clinical parameters were observed in all animals , but clinical signs relating to respiratory disease were not seen . | {
"id": "C0000768",
"pos": [
0,
13
],
"name": "Abnormalities"
} | {
"id": "C0035204",
"pos": [
99,
118
],
"name": "respiratory disease"
} | 0NA |
Lifestyle modification should be recommended for the prevention and treatment of hypertension in the general population . | {
"id": "C0199176",
"pos": [
53,
63
],
"name": "prevention"
} | {
"id": "C0020538",
"pos": [
81,
93
],
"name": "hypertension"
} | 0NA |
A major problem with cattle uterine viral infections in general , and BoHV-4 in particular , is our limited understanding of the pathogenic role(s ) that these infections play in the endometrium . | {
"id": "C0042149",
"pos": [
28,
35
],
"name": "uterine"
} | {
"id": "C0042769",
"pos": [
36,
52
],
"name": "viral infections"
} | 0NA |
Adrenal myelolipomas are rare benign tumors , usually discovered by chance in patients with hypertension , obesity or various endocrine disorders . | {
"id": "C0086692",
"pos": [
30,
43
],
"name": "benign tumors"
} | {
"id": "C0014130",
"pos": [
126,
145
],
"name": "endocrine disorders"
} | 0NA |
Replacement of the tryptophan residue gamma376 massively reduced the effect of the peptide on fibrin structure . | {
"id": "C0035139",
"pos": [
0,
11
],
"name": "Replacement"
} | {
"id": "C0041249",
"pos": [
19,
29
],
"name": "tryptophan"
} | 0NA |
The minigene transcript was expressed in kidney and adrenal tissues , but not liver , in five independent lines harboring a transgene with -2.5 kb of 5'-flanking sequence . | {
"id": "C0022646",
"pos": [
41,
47
],
"name": "kidney"
} | {
"id": "C0023884",
"pos": [
78,
83
],
"name": "liver"
} | 0NA |
Genomic DNA and RNA from adipose tissue biopsies were isolated before and after the dietary intervention . | {
"id": "C0005558",
"pos": [
40,
48
],
"name": "biopsies"
} | {
"id": "C0001527",
"pos": [
25,
39
],
"name": "adipose tissue"
} | 0NA |
Inflammatory cytokines are actively synthesized in the kidneys of patients with lupus nephritis and therefore , may play a role in its pathogenesis . | {
"id": "C0022646",
"pos": [
55,
62
],
"name": "kidneys"
} | {
"id": "C0024143",
"pos": [
80,
95
],
"name": "lupus nephritis"
} | 0NA |
Meanwhile , the hypoxia and pulmonary pathological damage were much improved . | {
"id": "C0024109",
"pos": [
28,
37
],
"name": "pulmonary"
} | {
"id": "C0242184",
"pos": [
16,
23
],
"name": "hypoxia"
} | 0NA |
Conversion of DA to DOPAC was also detected in several tissues incubated with DA in vitro ; in descending order of MAO activity ( pmol mg-1 h-1 at about 18 degrees C ) tissues tested were : skeletal muscle ( approximately 100 ) , Malpighian tubule ( approximately 50 ) , ovary ( approximately 45 ) , salivary gland ( approximately 30 ) , midgut ( approximately 20 ) , and haemolymph ( approximately 4 - 5 ) . | {
"id": "C0029939",
"pos": [
271,
276
],
"name": "ovary"
} | {
"id": "C0040300",
"pos": [
55,
62
],
"name": "tissues"
} | 0NA |
RPE65 is the major component of the retinal pigment epithelium ( RPE ) microsomal membrane , and it plays a critical role in the binding of retinoids involved in the visual cycle . | {
"id": "C0035298",
"pos": [
36,
43
],
"name": "retinal"
} | {
"id": "C0035322",
"pos": [
65,
68
],
"name": "RPE"
} | 0NA |
In agreement with this associative evidence , we have published recently that Ang II infusion induces aneurysmal pathology in the ascending aorta . | {
"id": "C0574032",
"pos": [
85,
93
],
"name": "infusion"
} | {
"id": "C0003956",
"pos": [
130,
145
],
"name": "ascending aorta"
} | 0NA |
Vitamin K1 administered IM was effective in treating the disease at dosages of 1.1 , 2.2 , and 3.3 mg/kg of body weight . | {
"id": "C0012634",
"pos": [
57,
64
],
"name": "disease"
} | {
"id": "C0005910",
"pos": [
108,
119
],
"name": "body weight"
} | 0NA |
Experimental studies have revealed that neonicotinoids pose potential risks for the nervous systems of non-target species , but the brain regions responsible for their behavioral effects remain incompletely understood . | {
"id": "C0027763",
"pos": [
84,
99
],
"name": "nervous systems"
} | {
"id": "C1273723",
"pos": [
132,
145
],
"name": "brain regions"
} | 0NA |
The procedure was applied to acid hydrolyzates of protein isolated from a range of foods ( milks processed at different temperatures , butter , cheese , infant formulae , bread , raw and cooked minced beef and olive oil ) . | {
"id": "C0184661",
"pos": [
4,
13
],
"name": "procedure"
} | {
"id": "C0069449",
"pos": [
210,
219
],
"name": "olive oil"
} | 0NA |
In conclusion , this study documented that ketosis was seasonal with lower incidence of this metabolic disease during hot seasons and with increased ambient temperature at calving . | {
"id": "C0025517",
"pos": [
93,
110
],
"name": "metabolic disease"
} | {
"id": "C0005903",
"pos": [
157,
168
],
"name": "temperature"
} | 0NA |
MRI studies were independently reviewed by two neuroradiologists for detection and localization of potential brain relapses . | {
"id": "C0006104",
"pos": [
109,
114
],
"name": "brain"
} | {
"id": "C0024485",
"pos": [
0,
3
],
"name": "MRI"
} | 0NA |
Plasmodium , the agent of malaria and the Apicomplexa most deadly to humans , multiplies in both hepatocytes and erythrocytes in the mammalian host . | {
"id": "C0024530",
"pos": [
26,
33
],
"name": "malaria"
} | {
"id": "C0014772",
"pos": [
113,
125
],
"name": "erythrocytes"
} | 0NA |
Easily diagnosed , the temporomandibular dysfunction syndrome is the result of teeth affections . | {
"id": "C0040426",
"pos": [
79,
84
],
"name": "teeth"
} | {
"id": "C0039496",
"pos": [
23,
61
],
"name": "temporomandibular dysfunction syndrome"
} | 0NA |
A popliteal clot was more dangerous if traction was used post-operatively , and if the dose of heparin was only a preventive dose . | {
"id": "C0040597",
"pos": [
39,
47
],
"name": "traction"
} | {
"id": "C0019134",
"pos": [
95,
102
],
"name": "heparin"
} | 0NA |
In another patient , reconstructive endovascular treatment ( stent with coiling ) was required in the chronic stage because the lesion deteriorated morphologically . | {
"id": "C0221198",
"pos": [
128,
134
],
"name": "lesion"
} | {
"id": "C0038257",
"pos": [
61,
66
],
"name": "stent"
} | 0NA |
Increasing knowledge of the IR role in cancer has important implications for cancer prevention , which should include control of insulin resistance and hyperinsulinemia in the population and meticulous evaluation of new antidiabetic drugs for their metabolic : mitogenic ratio . | {
"id": "C0006826",
"pos": [
39,
45
],
"name": "cancer"
} | {
"id": "C0020459",
"pos": [
152,
168
],
"name": "hyperinsulinemia"
} | 0NA |
Intracellular recordings from motoneurones in in vitro preparations of new-born rat spinal cord were used to study the sensitivity of the Ia excitatory post-synaptic potential ( e.p.s.p . ) to antagonists of excitatory amino acids , | {
"id": "C0002520",
"pos": [
219,
230
],
"name": "amino acids"
} | {
"id": "C0020517",
"pos": [
119,
130
],
"name": "sensitivity"
} | 0NA |
We determined the incidence of VHL and MEN type 2 among 62 German patients diagnosed with pheochromocytoma without a history of a hereditary disease . | {
"id": "C0019247",
"pos": [
130,
148
],
"name": "hereditary disease"
} | {
"id": "C0025268",
"pos": [
39,
49
],
"name": "MEN type 2"
} | 0NA |
Our data suggest that changes in the number and morphology of myelinated fibers in the proximal leg can confirm the diagnosis of neuropathy , and may help to distinguish between demyelinating and axonal neuropathy , and to differentiate pure small fiber neuropathy from early polyneuropathy . | {
"id": "C0023216",
"pos": [
96,
99
],
"name": "leg"
} | {
"id": "C0442874",
"pos": [
129,
139
],
"name": "neuropathy"
} | 0NA |
A high correlation was found between timing of cataract extraction and final BCVA of the better eye ( r = -0.55 , P = 0.00 ) . | {
"id": "C0015392",
"pos": [
96,
99
],
"name": "eye"
} | {
"id": "C0007389",
"pos": [
47,
66
],
"name": "cataract extraction"
} | 0NA |
The effects of several kinds of Ca(2+)-mobilizing drugs on cytoplasmic Ca2 + concentration ( [Ca2+]i ) were examined . | {
"id": "C0013227",
"pos": [
50,
55
],
"name": "drugs"
} | {
"id": "C0666743",
"pos": [
71,
74
],
"name": "Ca2"
} | 0NA |
We previously showed that pre-exposure of the cornea to Toll-like receptor 5 ligand flagellin induces profound mucosal innate protection against infections by modifying gene expression . | {
"id": "C0010031",
"pos": [
46,
52
],
"name": "cornea"
} | {
"id": "C0026724",
"pos": [
111,
118
],
"name": "mucosal"
} | 0NA |
Clinical examinations were performed for TDI , overjet and lip coverage . | {
"id": "C0023759",
"pos": [
59,
62
],
"name": "lip"
} | {
"id": "C0596028",
"pos": [
47,
54
],
"name": "overjet"
} | 0NA |
These results demonstrate that OXP induces a shift towards a Th2 response , inhibits TNF-alpha mRNA transcription locally in joint and systemically in spleen , and has a protective effect against arthritis similar to that produced by sTNFR in the HgCl2-treated BN rat . | {
"id": "C0022417",
"pos": [
125,
130
],
"name": "joint"
} | {
"id": "C0003864",
"pos": [
196,
205
],
"name": "arthritis"
} | 11finding_site_of |
The six-month protocol biopsies showed hepatitis C recurrence in 90 % of patients , without differences between groups . | {
"id": "C0005558",
"pos": [
23,
31
],
"name": "biopsies"
} | {
"id": "C0019196",
"pos": [
39,
50
],
"name": "hepatitis C"
} | 0NA |
Nitroprusside in leftf heart failure in acute myocardial infarction and Phentolamin in acute left ventricular failure due to critical rise in blood pressure . | {
"id": "C0031448",
"pos": [
72,
83
],
"name": "Phentolamin"
} | {
"id": "C0005823",
"pos": [
142,
156
],
"name": "blood pressure"
} | 0NA |
Local cerebral herniation due to ventricular dilatation was observed in a patient who had had removal of a bone flap and whose dura had previously been left open . | {
"id": "C0015252",
"pos": [
94,
101
],
"name": "removal"
} | {
"id": "C0013313",
"pos": [
127,
131
],
"name": "dura"
} | 0NA |
The first trial started in 1973 and compared the Halsted mastectomy with an extensive surgical resection ( quadrantectomy ) , associated with axillary dissection and radiotherapy ( QUART ) . | {
"id": "C0015252",
"pos": [
86,
104
],
"name": "surgical resection"
} | {
"id": "C0086383",
"pos": [
49,
67
],
"name": "Halsted mastectomy"
} | 0NA |
Radiographs showed no evidence of arthrosis in fourteen knees , grade-1 arthrosis in three , grade-2 in three , and grade-3 in two . | {
"id": "C0022742",
"pos": [
56,
61
],
"name": "knees"
} | {
"id": "C1306645",
"pos": [
0,
11
],
"name": "Radiographs"
} | 0NA |
These findings suggested that damage of the acinar cells by excess lysine resulted in breakdown of the mitochondrial membrane barrier to calcium as a very early abnormality , and that extracellular calcium then entered the mitochondrial matrices and inhibited mitochondrial function . | {
"id": "C0010957",
"pos": [
30,
36
],
"name": "damage"
} | {
"id": "C0006675",
"pos": [
137,
144
],
"name": "calcium"
} | 0NA |
LSS and MMN patients have several common clinical features : age at onset , weakness in the distribution of individual peripheral nerves , mild wasting , cramps and fasciculations , partial areflexia , and frequent stepwise disease course . | {
"id": "C0031119",
"pos": [
119,
136
],
"name": "peripheral nerves"
} | {
"id": "C0015644",
"pos": [
165,
179
],
"name": "fasciculations"
} | 0NA |
All patients underwent short TRH stimulation test showing an abnormal response in the vast majority of cases ( 65 % ) . | {
"id": "C0205161",
"pos": [
61,
69
],
"name": "abnormal"
} | {
"id": "C0040162",
"pos": [
29,
32
],
"name": "TRH"
} | 0NA |
Skin biopsy was supportive showing a dermis with coarse collagen . | {
"id": "C0011646",
"pos": [
37,
43
],
"name": "dermis"
} | {
"id": "C0150866",
"pos": [
0,
11
],
"name": "Skin biopsy"
} | 0NA |
Physiologically , these receptors could be activated by circulating epinephrine ( E ) and be involved in essential hypertension . | {
"id": "C0014563",
"pos": [
68,
79
],
"name": "epinephrine"
} | {
"id": "C0085580",
"pos": [
105,
127
],
"name": "essential hypertension"
} | 0NA |
Endometrial histology reveals cystic glandular dilation together with admixed estrogen ( mitotic ) and progestin ( secretory ) epithelial effects . | {
"id": "C0014939",
"pos": [
78,
86
],
"name": "estrogen"
} | {
"id": "C0033306",
"pos": [
103,
112
],
"name": "progestin"
} | 0NA |
FFI is a recently described prion disease characterized clinically by severe sleep impairment , dysautonomia , and motor signs , and pathologically by atrophy of thalamic nuclei , especially the medial dorsal and anterior ventral , and of the inferior olive . | {
"id": "C0333641",
"pos": [
151,
158
],
"name": "atrophy"
} | {
"id": "C0206042",
"pos": [
0,
3
],
"name": "FFI"
} | 0NA |
The left side of the testis was pulled through the inguinal ring to an inguinal canal divided by the abdominal wall , and then was retracted into the scrotum . | {
"id": "C0836916",
"pos": [
101,
115
],
"name": "abdominal wall"
} | {
"id": "C0225226",
"pos": [
51,
64
],
"name": "inguinal ring"
} | 0NA |
The stability at -20C and -70C of clindamycin , vancomycin , cephalothin , cefazolin , oxacillin , methicillin , nafcillin , and penicillin was analyzed using Staphylococcus eureus , Staphylococcus epidermidis , Enterococcus , and alpha Streptococcus as the test organisms . | {
"id": "C0027324",
"pos": [
113,
122
],
"name": "nafcillin"
} | {
"id": "C0008947",
"pos": [
34,
45
],
"name": "clindamycin"
} | 0NA |
When quetiapine and olanzapine were disaggregated , ORs were 1.61 95%CI ( 1.15 - 2.25 ) and 1.25 95%CI ( 0.89 - 1.74 ) , respectively . | {
"id": "C0171023",
"pos": [
20,
30
],
"name": "olanzapine"
} | {
"id": "C0123091",
"pos": [
5,
15
],
"name": "quetiapine"
} | 0NA |
Consequently it mediates enhancement of AKT activity and PML degradation , resulting in increased cellular proliferation , migration and metastasis . | {
"id": "C0020507",
"pos": [
98,
120
],
"name": "cellular proliferation"
} | {
"id": "C1627358",
"pos": [
25,
36
],
"name": "enhancement"
} | 0NA |
During the procedure , an extensive carcinomatous process was observed that rendered comprehension of the abdominal anatomy extremely difficult . | {
"id": "C0184661",
"pos": [
11,
20
],
"name": "procedure"
} | {
"id": "C0162340",
"pos": [
85,
98
],
"name": "comprehension"
} | 0NA |
The female , who had no syrinx , had hyperhidrosis and dissociated sensory loss of the head , neck , upper trunk , and arm , and anisocoria with the larger pupil ipsilateral to the sweating . | {
"id": "C0020458",
"pos": [
37,
50
],
"name": "hyperhidrosis"
} | {
"id": "C0038990",
"pos": [
181,
189
],
"name": "sweating"
} | 15interprets |
Nasopharyngeal exposure to simulated gastric juice causes eustachian tube dysfunction in rats . | {
"id": "C0027442",
"pos": [
0,
14
],
"name": "Nasopharyngeal"
} | {
"id": "C0271468",
"pos": [
58,
85
],
"name": "eustachian tube dysfunction"
} | 0NA |
Images on SD-OCT revealed dome-shaped hyperreflectivity beneath the retinal pigment epithelium ( RPE ) , corresponding to drusen . | {
"id": "C0035298",
"pos": [
68,
75
],
"name": "retinal"
} | {
"id": "C0035322",
"pos": [
97,
100
],
"name": "RPE"
} | 0NA |
HPV coinfection was significantly higher ( p < 0.01 ) in both the oral and cervical cells that had HSV infection . | {
"id": "C0226896",
"pos": [
66,
70
],
"name": "oral"
} | {
"id": "C0009450",
"pos": [
103,
112
],
"name": "infection"
} | 0NA |
The results of aging response show that BE-Mg-Y based alloy exhibits remarkable age hardening behaviour when the aging temperature is 200 ° C and higher . | {
"id": "C0001811",
"pos": [
113,
118
],
"name": "aging"
} | {
"id": "C0005903",
"pos": [
119,
130
],
"name": "temperature"
} | 0NA |
Besides these elements , altered cognitive capacity and abnormal urinary function prior to the infection and lead to an atypical clinical presentation . | {
"id": "C0205161",
"pos": [
56,
64
],
"name": "abnormal"
} | {
"id": "C0009450",
"pos": [
95,
104
],
"name": "infection"
} | 0NA |
Both Ab/SOD conjugates targeted to Plvap and CD31 accumulated in the lungs after IV injection in mice , but the former more profoundly inhibited LPS-induced pulmonary inflammation and elevation of plasma level of interferon-beta and -gamma and interleukin-27 . | {
"id": "C0024109",
"pos": [
69,
74
],
"name": "lungs"
} | {
"id": "C0032285",
"pos": [
157,
179
],
"name": "pulmonary inflammation"
} | 11finding_site_of |
The aim of the present article is to systematically review the evidence for functional brain changes associated with different treatment modalities for schizophrenia . | {
"id": "C0006104",
"pos": [
87,
92
],
"name": "brain"
} | {
"id": "C0036341",
"pos": [
152,
165
],
"name": "schizophrenia"
} | 0NA |
A favorable outcome in this type of invasive aspergillosis correlates with resolution of the bone marrow suppression and early antifungal medical therapy combined with aggressive surgical intervention for airway control , if needed . | {
"id": "C0005953",
"pos": [
93,
104
],
"name": "bone marrow"
} | {
"id": "C0238013",
"pos": [
36,
58
],
"name": "invasive aspergillosis"
} | 0NA |
Imipenem was highly active and bactericidal against all 100 strains of Pseudomonas pseudomallei tested , followed in activity by piperacillin , carumonam , ceftazidime , cefotaxime , and ceftriaxone . | {
"id": "C0020933",
"pos": [
0,
8
],
"name": "Imipenem"
} | {
"id": "C0007559",
"pos": [
156,
167
],
"name": "ceftazidime"
} | 0NA |
All the examinees were civilians exposed to war stress , so it could be directly designated as the cause of acute stress disorder and indirectly denoted as a trigger of cardiovascular , endocrine and cerebrovascular disorder that brought to stroke . | {
"id": "C0007226",
"pos": [
169,
183
],
"name": "cardiovascular"
} | {
"id": "C0038454",
"pos": [
241,
247
],
"name": "stroke"
} | 0NA |
The objective is to assess the operational feasibility of a population-wide ' blanket ' administration of SDR for leprosy prevention in isolated communities in a remote island . | {
"id": "C0199176",
"pos": [
122,
132
],
"name": "prevention"
} | {
"id": "C0023343",
"pos": [
114,
121
],
"name": "leprosy"
} | 0NA |
The two groups of hypertensives could not be distinguished on the basis of clinic blood pressure , plasma norepinephrine , epinephrine , renin activity or aldosterone . | {
"id": "C0014563",
"pos": [
123,
134
],
"name": "epinephrine"
} | {
"id": "C0002006",
"pos": [
155,
166
],
"name": "aldosterone"
} | 0NA |
We aimed to evaluate and compare the diagnostic accuracy of the early markers hFABP and myoglobin ( in terms of area under ROC curves , sensitivity and specificity ) to troponin I ( cTnI ) in a pragmatic group of patients presenting with chest pain . | {
"id": "C0020517",
"pos": [
136,
147
],
"name": "sensitivity"
} | {
"id": "C0008031",
"pos": [
238,
248
],
"name": "chest pain"
} | 0NA |
The frequencies of hip or any fracture ( since age 50 ) were similar in users and nonusers ( p = 0.80 and p = 0.51 , respectively ) . | {
"id": "C0019552",
"pos": [
19,
22
],
"name": "hip"
} | {
"id": "C0016658",
"pos": [
30,
38
],
"name": "fracture"
} | 0NA |
Pathological evaluation of this tissue showed disruption of the Bowman layer with band keratopathy , thickening of the basement membrane , and subepithelial fibrosis . | {
"id": "C0040300",
"pos": [
32,
38
],
"name": "tissue"
} | {
"id": "C0004799",
"pos": [
119,
136
],
"name": "basement membrane"
} | 0NA |
The data obtained suggest connections among such properties of the auditory system as frequency selectivity , adaptation and loudness recruitment . | {
"id": "C0587901",
"pos": [
67,
82
],
"name": "auditory system"
} | {
"id": "C0271510",
"pos": [
134,
145
],
"name": "recruitment"
} | 11finding_site_of |
The patient failed to respond to pulsed dye laser , but intralesional triamcinolone combined with cryotherapy led to an acceptable response . | {
"id": "C0040864",
"pos": [
70,
83
],
"name": "triamcinolone"
} | {
"id": "C4551716",
"pos": [
98,
109
],
"name": "cryotherapy"
} | 0NA |
An indirect fluorescent antibody test was used to determine specific antibodies . | {
"id": "C0003241",
"pos": [
69,
79
],
"name": "antibodies"
} | {
"id": "C0201284",
"pos": [
12,
37
],
"name": "fluorescent antibody test"
} | 6component_of |
The monoclonal antibody did not block the catalytic activity of glutathione S-transferase B toward cumene hydroperoxide and possibly also 1-chloro-2,4-dinitrobenzene . | {
"id": "C0028778",
"pos": [
32,
37
],
"name": "block"
} | {
"id": "C0003250",
"pos": [
4,
23
],
"name": "monoclonal antibody"
} | 0NA |
Individuals with acquired neurological disorders were retested within an average of 9.6 days after the first assessment . | {
"id": "C0031809",
"pos": [
109,
119
],
"name": "assessment"
} | {
"id": "C0027765",
"pos": [
26,
48
],
"name": "neurological disorders"
} | 0NA |
In conclusion , the present results indicate that SCO induced cognitive dysfunction and oxidative stress may involve brain mitochondrial impairment , an important target for new neuroprotective compounds against AD and other dementias . | {
"id": "C0006104",
"pos": [
117,
122
],
"name": "brain"
} | {
"id": "C0497327",
"pos": [
225,
234
],
"name": "dementias"
} | 11finding_site_of |
Hysterectomy , whether abdominal , vaginal , or laparoscopic will then be applied to ablation failures or non-candidates . | {
"id": "C0042232",
"pos": [
35,
42
],
"name": "vaginal"
} | {
"id": "C0031150",
"pos": [
48,
60
],
"name": "laparoscopic"
} | 0NA |
The mechanical properties of articular cartilage have been shown to reflect the extent of cartilage degeneration in human osteoarthritis and in experimental models of joint disease , but there is little experimental data documenting changes in cartilage mechanics following meniscectomy . | {
"id": "C0007303",
"pos": [
29,
48
],
"name": "articular cartilage"
} | {
"id": "C1285228",
"pos": [
90,
112
],
"name": "cartilage degeneration"
} | 0NA |
Adult male rats previously exposed on gestation days ( GD ) 12 - 21 to di(n-butyl ) phthalate ( DBP ) have reproductive tract malformations , particularly agenesis of the epididymis , decreased sperm production , and Leydig cell hyperplasia and adenomas . | {
"id": "C0000846",
"pos": [
155,
163
],
"name": "agenesis"
} | {
"id": "C0001430",
"pos": [
245,
253
],
"name": "adenomas"
} | 0NA |
Recovery of OA as OA-Me2 from chicken kidney homogenates and human plasma was quantitative following simple extraction and cleanup procedures , reaction with diazomethane , and HPLC analysis . | {
"id": "C0022646",
"pos": [
38,
44
],
"name": "kidney"
} | {
"id": "C0032105",
"pos": [
67,
73
],
"name": "plasma"
} | 0NA |
Selective injection is useful in the course of an intervention , to facilitate navigation , provide information on flow conditions , and to evaluate treatment progress repeatedly . | {
"id": "C0184661",
"pos": [
50,
62
],
"name": "intervention"
} | {
"id": "C0021485",
"pos": [
10,
19
],
"name": "injection"
} | 0NA |
The Herrick lacrimal occlusion device sometimes can not be removed by simple irrigation and is capable of inducing permanent , irreversible , symptomatic lacrimal drainage system obstruction . | {
"id": "C0028778",
"pos": [
179,
190
],
"name": "obstruction"
} | {
"id": "C0022100",
"pos": [
77,
87
],
"name": "irrigation"
} | 0NA |
Plasmocytoid urothelial carcinoma is a rare subtype of tumour of the urinary bladder . | {
"id": "C0027651",
"pos": [
55,
61
],
"name": "tumour"
} | {
"id": "C0005682",
"pos": [
69,
84
],
"name": "urinary bladder"
} | 0NA |
Specifically , CM-LPS complexes are principally removed from the circulation by the liver with a rapid plasma half-life approximating that for CM alone . | {
"id": "C0023884",
"pos": [
84,
89
],
"name": "liver"
} | {
"id": "C0032105",
"pos": [
103,
109
],
"name": "plasma"
} | 0NA |
Damage to specific white matter tracts within the spinal cord can often result in the particular neurological syndromes that characterize myelopathies such as traumatic spinal cord injury . | {
"id": "C0037925",
"pos": [
50,
61
],
"name": "spinal cord"
} | {
"id": "C0037928",
"pos": [
138,
150
],
"name": "myelopathies"
} | 11finding_site_of |
Furthermore , viral-mediated HDAC5 overexpression in the hippocampus blocked imipramine 's ability to reverse depression-like behavior . | {
"id": "C0028778",
"pos": [
69,
76
],
"name": "blocked"
} | {
"id": "C0019564",
"pos": [
57,
68
],
"name": "hippocampus"
} | 0NA |
We conducted a systematic review and critical assessment of the available evidence pertaining to the epidemiology , pathophysiology , diagnosis and management of hirsutism . | {
"id": "C0031809",
"pos": [
46,
56
],
"name": "assessment"
} | {
"id": "C0019572",
"pos": [
162,
171
],
"name": "hirsutism"
} | 0NA |
We describe the clinical and neuropathologic features of two patients with angiosarcoma of the brain and review the previously published cases described to date . | {
"id": "C0006104",
"pos": [
95,
100
],
"name": "brain"
} | {
"id": "C0018923",
"pos": [
75,
87
],
"name": "angiosarcoma"
} | 0NA |
Apart from the judgment of the severity of the stenosing coronary arteriosclerosis it serves intravitally for the estimation of the endangering by myocardial infarction . | {
"id": "C0027051",
"pos": [
147,
168
],
"name": "myocardial infarction"
} | {
"id": "C0010054",
"pos": [
57,
82
],
"name": "coronary arteriosclerosis"
} | 0NA |
We found no independent association of RRI with diabetes mellitus , hypertension treatment , smoking , cholesterol levels , or estimated glomerular filtration rate . | {
"id": "C0011849",
"pos": [
48,
65
],
"name": "diabetes mellitus"
} | {
"id": "C0020538",
"pos": [
68,
80
],
"name": "hypertension"
} | 0NA |
Visual acuity was estimated based on the results of peak RGC density and ocular anatomical parameters . | {
"id": "C0015392",
"pos": [
73,
79
],
"name": "ocular"
} | {
"id": "C0042812",
"pos": [
0,
13
],
"name": "Visual acuity"
} | 0NA |
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