text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Six large , placebo-controlled , short-term RCTs over the last 4 years demonstrated that aripiprazole , olanzapine , paliperidone , quetiapine and risperidone , but not ziprasidone , were superior to placebo . | {
"id": "C0171023",
"pos": [
104,
114
],
"name": "olanzapine"
} | {
"id": "C0123091",
"pos": [
132,
142
],
"name": "quetiapine"
} | 0NA |
Mononuclear cell infiltration often containing giant cells in ceca , livers , kidneys and a proventriculus was observed . | {
"id": "C0022646",
"pos": [
78,
85
],
"name": "kidneys"
} | {
"id": "C0023884",
"pos": [
69,
75
],
"name": "livers"
} | 0NA |
Postoperative analgesia included acetaminophen , a continuous infusion of 0.2 % ropivacaine at 7 mL hr(-1 ) , and intravenous morphine if the visual analogue scale ( VAS ) pain score was > 3 on a 0 - 10 scale . | {
"id": "C0574032",
"pos": [
62,
70
],
"name": "infusion"
} | {
"id": "C0000970",
"pos": [
33,
46
],
"name": "acetaminophen"
} | 0NA |
In pituitary adenomas typical visual field ( VF ) defect is bitemporal hemianopsia but tumor size and optic chiasmal position may cause variable VF defects and VF examination may remain normal . | {
"id": "C0015392",
"pos": [
102,
107
],
"name": "optic"
} | {
"id": "C0221184",
"pos": [
60,
82
],
"name": "bitemporal hemianopsia"
} | 11finding_site_of |
GPER-1 expression was analyzed by immunohistochemistry in 35 benign ovarian tumors , 35 tumors of low-malignant potential and in 124 ovarian cancers . | {
"id": "C0027651",
"pos": [
88,
94
],
"name": "tumors"
} | {
"id": "C0919267",
"pos": [
68,
82
],
"name": "ovarian tumors"
} | 3associated_morphology_of |
• DWI has added value for assessment of tumor margin infiltration in soft tissue sarcoma . | {
"id": "C0031809",
"pos": [
26,
36
],
"name": "assessment"
} | {
"id": "C0598801",
"pos": [
2,
5
],
"name": "DWI"
} | 0NA |
Many different types of foot orthoses are used to treat biomechanical dysfunction of the foot . | {
"id": "C0016504",
"pos": [
89,
93
],
"name": "foot"
} | {
"id": "C0087111",
"pos": [
50,
55
],
"name": "treat"
} | 0NA |
The distribution of genotypes of the MTHFR was different according to blood pressure ( BP ) , it was observed that the TT genotype had lower frequency in HBP ( p<0.001 ) . | {
"id": "C0020538",
"pos": [
154,
157
],
"name": "HBP"
} | {
"id": "C0005823",
"pos": [
70,
84
],
"name": "blood pressure"
} | 15interprets |
Intestinal epithelial cell proliferation , migration , and differentiation are susceptible to various influences along the crypt-villus axis including compositional changes in the basement membrane and differential expression of receptors for these components . | {
"id": "C0021853",
"pos": [
0,
10
],
"name": "Intestinal"
} | {
"id": "C0004799",
"pos": [
180,
197
],
"name": "basement membrane"
} | 0NA |
This process was slowed down by temperature fall to about 8 degrees C , but only in the range of low concentrations ( 1 - 32 mg/l ) . | {
"id": "C0085639",
"pos": [
44,
48
],
"name": "fall"
} | {
"id": "C0005903",
"pos": [
32,
43
],
"name": "temperature"
} | 0NA |
The rehabilitation program after flexor tendon repair of zone II laceration varies . | {
"id": "C0043246",
"pos": [
65,
75
],
"name": "laceration"
} | {
"id": "C0034991",
"pos": [
4,
26
],
"name": "rehabilitation program"
} | 0NA |
Bleomycin-detectable iron can stimulate damaging free radical reactions , and its persistence in plasma even after prolonged venesection might contribute to the tissue damage that results from iron overload . | {
"id": "C0010957",
"pos": [
161,
174
],
"name": "tissue damage"
} | {
"id": "C0282193",
"pos": [
193,
206
],
"name": "iron overload"
} | 0NA |
Collagen shields , especially combined with vitamin A and EGF , can be employed as a therapeutic concept offering accelerated epithelial wound closure after keratoplasty . | {
"id": "C0042839",
"pos": [
44,
53
],
"name": "vitamin A"
} | {
"id": "C0087111",
"pos": [
85,
96
],
"name": "therapeutic"
} | 0NA |
Common barriers were negative attitudes toward use of agonist pharmacotherapy , payment environment , and physician prescribing capacity . | {
"id": "C0013216",
"pos": [
62,
77
],
"name": "pharmacotherapy"
} | {
"id": "C0004271",
"pos": [
30,
39
],
"name": "attitudes"
} | 0NA |
Physiological processes in general are sensitive to temperature . | {
"id": "C0020517",
"pos": [
39,
48
],
"name": "sensitive"
} | {
"id": "C0005903",
"pos": [
52,
63
],
"name": "temperature"
} | 0NA |
However , large clinical trials are needed to assess progesterone as a promising drug in DAI . | {
"id": "C0013227",
"pos": [
81,
85
],
"name": "drug"
} | {
"id": "C0033308",
"pos": [
53,
65
],
"name": "progesterone"
} | 0NA |
Ruptured microaneurysms are a frequent cause of retinal hemorrhage in immunosuppressed patients . | {
"id": "C0035298",
"pos": [
48,
55
],
"name": "retinal"
} | {
"id": "C0019080",
"pos": [
56,
66
],
"name": "hemorrhage"
} | 0NA |
We aimed to evaluate the value of immunoglobulin ( Ig ) G , IgM , and IgA isotypes of anti-double-stranded DNA ( anti-dsDNA ) and anti-C1q antibody in diagnosing systemic lupus erythematosus ( SLE ) patients and elucidate their association with disease activity and lupus nephritis . | {
"id": "C0024141",
"pos": [
162,
190
],
"name": "systemic lupus erythematosus"
} | {
"id": "C0024143",
"pos": [
266,
281
],
"name": "lupus nephritis"
} | 5cause_of |
Contemporary effective population sizes of all groups within Microdipodops appear to be low ( < 500 ) , suggesting that each genetic lineage may have difficulty coping with changing environmental pressures and hence may be at risk of extirpation . | {
"id": "C1299586",
"pos": [
150,
160
],
"name": "difficulty"
} | {
"id": "C0015252",
"pos": [
234,
245
],
"name": "extirpation"
} | 0NA |
Here , we report the construction and properties of the improved set of yeast strains designed along with such screening also for a global analysis of genetic suppressors of multidrug resistance . | {
"id": "C0441513",
"pos": [
21,
33
],
"name": "construction"
} | {
"id": "C0080194",
"pos": [
78,
85
],
"name": "strains"
} | 0NA |
Using a murine model of myocarditis caused by coxsackievirus B3 ( CVB3 ) , we previously reported that the heart is infiltrated first by natural killer cells , which express a cytolytic factor , perforin , and then by activated T cells . | {
"id": "C0018787",
"pos": [
107,
112
],
"name": "heart"
} | {
"id": "C0027059",
"pos": [
24,
35
],
"name": "myocarditis"
} | 0NA |
Seasonal changes of aquarium temperature ranged from 15 to 25 & deg;C. The isolated hearts were subjected to cooling experiments . | {
"id": "C0018787",
"pos": [
84,
90
],
"name": "hearts"
} | {
"id": "C0005903",
"pos": [
29,
40
],
"name": "temperature"
} | 0NA |
In Xenopus laevis , dark-reared from early life , the visuotectal map through the ipsilateral eye exhibits significant signs of disorder indicating that the normal development of the underlying " intertectal " system involves experience-dependent processes . | {
"id": "C0015392",
"pos": [
94,
97
],
"name": "eye"
} | {
"id": "C0012634",
"pos": [
128,
136
],
"name": "disorder"
} | 0NA |
The authors ' data do not suggest that controls are more reluctant to report a history of induced abortion than are women with breast cancer . | {
"id": "C0006142",
"pos": [
127,
140
],
"name": "breast cancer"
} | {
"id": "C0156543",
"pos": [
98,
106
],
"name": "abortion"
} | 0NA |
This introduction describes the principles governing microarray construction and use , focusing on practical challenges faced when conducting SMM experiments . | {
"id": "C0441513",
"pos": [
64,
76
],
"name": "construction"
} | {
"id": "C1531608",
"pos": [
142,
145
],
"name": "SMM"
} | 0NA |
Episodes were co-incident with disease severity markers : coma ( 57 % ) , circulatory failure ( 38 % ) and respiratory distress ( 21 % ) but less commonly with seizures ( 10 % ) . | {
"id": "C0476273",
"pos": [
107,
127
],
"name": "respiratory distress"
} | {
"id": "C0036572",
"pos": [
160,
168
],
"name": "seizures"
} | 0NA |
The ranking of OCs by progestogen potency does not take the estrogen content into consideration . | {
"id": "C0014939",
"pos": [
60,
68
],
"name": "estrogen"
} | {
"id": "C0033306",
"pos": [
22,
33
],
"name": "progestogen"
} | 0NA |
Dietary intake of citrus limonoids may provide a protective effect against the onset of various cancers and other xenobiotic related diseases . | {
"id": "C0006826",
"pos": [
96,
103
],
"name": "cancers"
} | {
"id": "C0012634",
"pos": [
133,
141
],
"name": "diseases"
} | 0NA |
Lymphocytic aggregates ( follicles ) were found in the palatoglossal folds and the gingiva . | {
"id": "C0221971",
"pos": [
25,
34
],
"name": "follicles"
} | {
"id": "C0017562",
"pos": [
83,
90
],
"name": "gingiva"
} | 0NA |
Hepatitis B virus is a hepatotropic virus that causes acute and chronic hepatitis , liver cirrhosis , and hepatocellular carcinoma ; it is responsible for more than one million deaths annually worldwide despite hepatitis B vaccination . | {
"id": "C0019163",
"pos": [
211,
222
],
"name": "hepatitis B"
} | {
"id": "C0019189",
"pos": [
64,
81
],
"name": "chronic hepatitis"
} | 0NA |
This paper presents a definitive overview ofthe pulmonary toxicity of MDI developed following a thorough review of both investigations . | {
"id": "C0024109",
"pos": [
48,
57
],
"name": "pulmonary"
} | {
"id": "C1261322",
"pos": [
120,
134
],
"name": "investigations"
} | 0NA |
Giardia duodenalis and Enterocytozoon bieneusi are two common protozoa that parasitize the intestinal epithelium of animals and humans . | {
"id": "C0021853",
"pos": [
91,
101
],
"name": "intestinal"
} | {
"id": "C0014609",
"pos": [
102,
112
],
"name": "epithelium"
} | 0NA |
Reversible blockade of electron transport at complex I immediately before sustained ischemia also preserves mitochondrial respiration and decreases infarct size . | {
"id": "C0022116",
"pos": [
84,
92
],
"name": "ischemia"
} | {
"id": "C0035203",
"pos": [
122,
133
],
"name": "respiration"
} | 0NA |
The recent success of PD-1/PD-L1 antibodies for advanced cancer treatment has led to the conclusion that activating the immune system can be employed to fight cancer . | {
"id": "C0020962",
"pos": [
120,
133
],
"name": "immune system"
} | {
"id": "C0006826",
"pos": [
159,
165
],
"name": "cancer"
} | 0NA |
The HCM Risk-SCD model can be used for SCD prediction in patients undergoing ASA . | {
"id": "C0004057",
"pos": [
77,
80
],
"name": "ASA"
} | {
"id": "C0002895",
"pos": [
39,
42
],
"name": "SCD"
} | 0NA |
It is probable that the dynamic lung compliance ( < 20ml/cmH2O ) , PIP ( > 50 cm H2O ) at conventional I : E ratio ( 1:2 ) ventilation ( 10 ml/kg ) with hypotension might form the basis to develop a scoring system for guidance to switch over to PC-IRV ventilation . | {
"id": "C0150600",
"pos": [
218,
226
],
"name": "guidance"
} | {
"id": "C0035203",
"pos": [
123,
134
],
"name": "ventilation"
} | 0NA |
After vaccination , mice were challenged with PCV2 virus , and virus titers in the lungs and lymph nodes were measured . | {
"id": "C0024109",
"pos": [
83,
88
],
"name": "lungs"
} | {
"id": "C0024204",
"pos": [
93,
104
],
"name": "lymph nodes"
} | 0NA |
The population consisted of 32 women undergoing a tension-free vaginal tape ( TVT ) operation under a spinal anaesthetic . | {
"id": "C0002928",
"pos": [
102,
120
],
"name": "spinal anaesthetic"
} | {
"id": "C0543467",
"pos": [
84,
93
],
"name": "operation"
} | 0NA |
These concerns are particularly important for the obese surgical patient . | {
"id": "C0028754",
"pos": [
50,
55
],
"name": "obese"
} | {
"id": "C0543467",
"pos": [
56,
64
],
"name": "surgical"
} | 0NA |
From the retrospective analysis of 36 surgically verified cases it became evident that hypertrophic scar tissue shows definite contrast enhancement , whereas recurrent disc herniation remains unenhanced . | {
"id": "C0019270",
"pos": [
173,
183
],
"name": "herniation"
} | {
"id": "C0040300",
"pos": [
105,
111
],
"name": "tissue"
} | 0NA |
Accumulation and aggregation of amyloid-β ( Aβ ) peptides in the brain trigger the development of progressive neurodegeneration and dementia associated with Alzheimer 's disease ( AD ) . | {
"id": "C0006104",
"pos": [
65,
70
],
"name": "brain"
} | {
"id": "C0011265",
"pos": [
132,
140
],
"name": "dementia"
} | 11finding_site_of |
Studies in children uniformly recommend saliva for therapeutic monitoring of phenytoin , carbamazepine and phenobarbital . | {
"id": "C0031507",
"pos": [
77,
86
],
"name": "phenytoin"
} | {
"id": "C0150369",
"pos": [
63,
73
],
"name": "monitoring"
} | 0NA |
All 12 sickle cell anemia patients were found to have alpha-thalassemia2 ( alpha-thal2 ) , either in the homozygous or heterozygous condition . | {
"id": "C0002871",
"pos": [
19,
25
],
"name": "anemia"
} | {
"id": "C0012634",
"pos": [
132,
141
],
"name": "condition"
} | 0NA |
The procedure allows separation of macromolecules by ion-exchange chromatography , density gradient centrifugation , or molecular sieve chromatography and involves spotting onto cellulose acetate membrane , reaction with Alcian blue , and quantitation of color in a spectrophotometer . | {
"id": "C0184661",
"pos": [
4,
13
],
"name": "procedure"
} | {
"id": "C0001933",
"pos": [
221,
232
],
"name": "Alcian blue"
} | 0NA |
Transplant physicians are constantly faced with the challenge of estimating the recipients ' immunologic risk and tailoring their immunosuppression accordingly . | {
"id": "C0040732",
"pos": [
0,
10
],
"name": "Transplant"
} | {
"id": "C0021079",
"pos": [
130,
147
],
"name": "immunosuppression"
} | 0NA |
People with type 2 diabetes mellitus ( T2DM ) have abnormal peripheral and central haemodynamics at rest and during exercise , probably due to metabolic perturbations , but mechanisms are unknown . | {
"id": "C0205161",
"pos": [
51,
59
],
"name": "abnormal"
} | {
"id": "C0011860",
"pos": [
12,
36
],
"name": "type 2 diabetes mellitus"
} | 0NA |
One week after the 2nd operation , the flap showed normal color . | {
"id": "C0543467",
"pos": [
23,
32
],
"name": "operation"
} | {
"id": "C0038925",
"pos": [
39,
43
],
"name": "flap"
} | 0NA |
Larger vessels arising from either side of the rete divided into the long- and short-terminal arteries that supplied an extensive submucosal plexus , which was continuous around the circumference . | {
"id": "C0005847",
"pos": [
7,
14
],
"name": "vessels"
} | {
"id": "C0038564",
"pos": [
130,
147
],
"name": "submucosal plexus"
} | 0NA |
The cases of ureteral distension without reflux had a similar favourable course after removal of the obstruction of the lower urinary tract . | {
"id": "C0015252",
"pos": [
86,
93
],
"name": "removal"
} | {
"id": "C0521620",
"pos": [
13,
32
],
"name": "ureteral distension"
} | 0NA |
Their specialty choices contribute to shaping the balance of the future medical workforce , with views on general practice ( GP ) careers of particular interest because of current recruitment difficulties . | {
"id": "C1299586",
"pos": [
192,
204
],
"name": "difficulties"
} | {
"id": "C0271510",
"pos": [
180,
191
],
"name": "recruitment"
} | 0NA |
Even in these regions , binding sites for iloprost had several features clearly different from those for prostaglandin E2 . | {
"id": "C0012472",
"pos": [
105,
121
],
"name": "prostaglandin E2"
} | {
"id": "C0079594",
"pos": [
42,
50
],
"name": "iloprost"
} | 0NA |
To address the molecular mechanisms of liver function , we integrated multiple gene expression datasets from microarray , MPSS , SAGE and EST platforms to generate a transcriptome atlas of the normal human liver . | {
"id": "C0023884",
"pos": [
206,
211
],
"name": "liver"
} | {
"id": "C0013806",
"pos": [
138,
141
],
"name": "EST"
} | 0NA |
The most frequent emergencies are : appendicitis , intussusceptions , hypertrophic pyloric stenosis , volvulus due to intestinal malrotation . | {
"id": "C0021933",
"pos": [
51,
67
],
"name": "intussusceptions"
} | {
"id": "C0700639",
"pos": [
70,
99
],
"name": "hypertrophic pyloric stenosis"
} | 0NA |
A broad and fundamental understanding of how neurons adapt to hypoxia is likely to help guide efforts to find new treatments for brain hypoxia and ischemia . | {
"id": "C0022116",
"pos": [
147,
155
],
"name": "ischemia"
} | {
"id": "C1527348",
"pos": [
129,
142
],
"name": "brain hypoxia"
} | 0NA |
The only nerve observed within the adductor canal was the saphenous nerve . | {
"id": "C0027740",
"pos": [
9,
14
],
"name": "nerve"
} | {
"id": "C0225273",
"pos": [
35,
49
],
"name": "adductor canal"
} | 0NA |
To summarize the experience in surgical treatment of patients with intracranial aneurysms . | {
"id": "C0007766",
"pos": [
67,
89
],
"name": "intracranial aneurysms"
} | {
"id": "C0543467",
"pos": [
31,
49
],
"name": "surgical treatment"
} | 0NA |
Our study suggests that RIG1-PGD2 signaling might play an important role in cancer cell suppression in the testis . | {
"id": "C0039597",
"pos": [
107,
113
],
"name": "testis"
} | {
"id": "C0221103",
"pos": [
88,
99
],
"name": "suppression"
} | 0NA |
Several circumstances where these tuning curves are helpful , are presented : assessment of tinnitus , Menière 's disease , unclear impairment of speech intelligibility . | {
"id": "C0031809",
"pos": [
78,
88
],
"name": "assessment"
} | {
"id": "C0040264",
"pos": [
92,
100
],
"name": "tinnitus"
} | 0NA |
The higher presence of antibodies against MBP and their MAP and EBV homologous in CSF during relapses suggests a possible role of the pathogens in enhancing inflammation . | {
"id": "C0021368",
"pos": [
157,
169
],
"name": "inflammation"
} | {
"id": "C0003241",
"pos": [
23,
33
],
"name": "antibodies"
} | 0NA |
En-face OCT images may reveal a petaloid aspect of the macula due to cysts in the inner retina segmentation , when FA shows no leakage . | {
"id": "C0010709",
"pos": [
69,
74
],
"name": "cysts"
} | {
"id": "C0227662",
"pos": [
55,
61
],
"name": "macula"
} | 0NA |
A novel index , the serum aspartate aminotransferase activity/platelet count ratio index ( APRI ) , has been identified as a biochemical surrogate for histological fibrogenesis and fibrosis in cirrhosis . | {
"id": "C0016059",
"pos": [
181,
189
],
"name": "fibrosis"
} | {
"id": "C0023890",
"pos": [
193,
202
],
"name": "cirrhosis"
} | 0NA |
The causes of arytenoid dislocation were intubation ( n = 9 ) and blunt trauma ( n = 2 ) . | {
"id": "C0021925",
"pos": [
41,
51
],
"name": "intubation"
} | {
"id": "C0043253",
"pos": [
66,
78
],
"name": "blunt trauma"
} | 0NA |
However , the gastrointestinal adverse effects , including ulcers , perforation and bleeding , constitute a major problem , although the risk of their occurrence appears to vary according to the different classical NSAIDs used . | {
"id": "C0019080",
"pos": [
84,
92
],
"name": "bleeding"
} | {
"id": "C0041582",
"pos": [
59,
65
],
"name": "ulcers"
} | 0NA |
The systolic and diastolic functions of the hearts increased very significantly when the perfusion solution was changed to isotonic solution from the hypertonic solutions . | {
"id": "C0018787",
"pos": [
44,
50
],
"name": "hearts"
} | {
"id": "C0031001",
"pos": [
89,
98
],
"name": "perfusion"
} | 0NA |
We investigated the real-world effectiveness of several drugs ( including short- and long-acting beta-agonists [ SABAs and LABAs ] , inhaled corticosteroids [ ICS ] , and antibiotics ) in preventing severe asthma exacerbations by carrying-out a large observational study based on the healthcare utilization databases of the Italian Lombardy Region . | {
"id": "C0013227",
"pos": [
56,
61
],
"name": "drugs"
} | {
"id": "C0004096",
"pos": [
206,
212
],
"name": "asthma"
} | 0NA |
Pigmented tumors of the eyelid are often difficult to identify accurately , as different tumors may have the same clinical presentation . | {
"id": "C0027651",
"pos": [
89,
95
],
"name": "tumors"
} | {
"id": "C0015426",
"pos": [
24,
30
],
"name": "eyelid"
} | 0NA |
Previous reports of temporal arteritis with coronary involvement are summarized . | {
"id": "C0018787",
"pos": [
44,
52
],
"name": "coronary"
} | {
"id": "C1956391",
"pos": [
20,
38
],
"name": "temporal arteritis"
} | 0NA |
After ( TV+A ) , spontaneous activity in the antrum and duodenum was abolished and vagal stimulation did not increase motility in these organs . | {
"id": "C0013303",
"pos": [
56,
64
],
"name": "duodenum"
} | {
"id": "C0034193",
"pos": [
45,
51
],
"name": "antrum"
} | 0NA |
Examination of bone marrow revealed prominent erythroid hyperplasia ; 18 % of the erythroblasts were distinct ringed sideroblasts . | {
"id": "C0031809",
"pos": [
0,
11
],
"name": "Examination"
} | {
"id": "C0005953",
"pos": [
15,
26
],
"name": "bone marrow"
} | 0NA |
However , this observed enhancement for the lipid encapsulated form is more than the starch counterpart , which can be related to its smaller size . | {
"id": "C0023779",
"pos": [
44,
49
],
"name": "lipid"
} | {
"id": "C0038179",
"pos": [
85,
91
],
"name": "starch"
} | 0NA |
A significant correlation ( p = 0.03 ) was found in DAI reduction of the ACM before and during SNS as compared to the clinical improvement in overactive bladder symptoms . | {
"id": "C0005682",
"pos": [
153,
160
],
"name": "bladder"
} | {
"id": "C0039044",
"pos": [
95,
98
],
"name": "SNS"
} | 0NA |
Among the lesions , transplant glomerulopathy scoring by virtual slides showed the highest inter-observer reproducibility , with a similar accuracy to glass slides . | {
"id": "C0221198",
"pos": [
10,
17
],
"name": "lesions"
} | {
"id": "C0403601",
"pos": [
20,
45
],
"name": "transplant glomerulopathy"
} | 0NA |
This retrospective review examined patients undergoing SLN biopsy for cutaneous melanoma of the head and neck between July 2003 and December 2015 . | {
"id": "C0018670",
"pos": [
96,
100
],
"name": "head"
} | {
"id": "C0025202",
"pos": [
70,
88
],
"name": "cutaneous melanoma"
} | 0NA |
At craniotomy , incision of the lamina terminalis exposed intraventricular craniopharyngioma with anterior extension into the chiasm and proximal optic nerves . | {
"id": "C0029130",
"pos": [
146,
158
],
"name": "optic nerves"
} | {
"id": "C0184898",
"pos": [
16,
24
],
"name": "incision"
} | 0NA |
Thirty-eight isolates ( 3.8 % ) showed resistance to one of the following drugs : streptomycin ( S ) , isoniazid ( H ) , rifampicin ( R ) or ethambutol ( E ) . | {
"id": "C0013227",
"pos": [
74,
79
],
"name": "drugs"
} | {
"id": "C0035608",
"pos": [
121,
131
],
"name": "rifampicin"
} | 0NA |
Understanding the nitric oxide molecular mechanisms of signaling pathways in the heart can provide a new strategic approach to prevention and treatment of cardiovascular diseases . | {
"id": "C0199176",
"pos": [
127,
137
],
"name": "prevention"
} | {
"id": "C0028128",
"pos": [
18,
30
],
"name": "nitric oxide"
} | 0NA |
As is true for any other malignancy , one must determine which tumor features , patient factors , and laboratory techniques will provide diagnostic and prognostic information for patients with RCC . | {
"id": "C0006826",
"pos": [
25,
35
],
"name": "malignancy"
} | {
"id": "C0007134",
"pos": [
193,
196
],
"name": "RCC"
} | 0NA |
Gastric adenocarcinoma is the third leading cause of cancer-related death worldwide , but no models exist to readily investigate distant metastases that are mainly responsible for mortality in this disease . | {
"id": "C0012634",
"pos": [
198,
205
],
"name": "disease"
} | {
"id": "C0278701",
"pos": [
0,
22
],
"name": "Gastric adenocarcinoma"
} | 0NA |
A high salt diet significantly elevated blood pressure only in the beta3-null mice and resulted in hypertrophic changes in the aortic smooth muscle layer and cardiac enlargement . | {
"id": "C0020564",
"pos": [
99,
111
],
"name": "hypertrophic"
} | {
"id": "C0005823",
"pos": [
40,
54
],
"name": "blood pressure"
} | 0NA |
In turn , HNEpC treated with methacholine and dexamethasone showed the same trends as those intervened separately with these 2 drugs . | {
"id": "C0013227",
"pos": [
127,
132
],
"name": "drugs"
} | {
"id": "C0600370",
"pos": [
29,
41
],
"name": "methacholine"
} | 0NA |
The health providers ' attitudes , care and support gave positive and negative birth experiences . | {
"id": "C0205160",
"pos": [
70,
78
],
"name": "negative"
} | {
"id": "C0005615",
"pos": [
79,
84
],
"name": "birth"
} | 0NA |
A cystoscopy was performed and showed metastases to the mucosa of the bladder . | {
"id": "C0005682",
"pos": [
70,
77
],
"name": "bladder"
} | {
"id": "C0010702",
"pos": [
2,
12
],
"name": "cystoscopy"
} | 9direct_procedure_site_of |
For aphakic eyes , 50.5 % presented with visual acuity better than or equal to 6/18 ; 82.6 % with best-correction . | {
"id": "C0015392",
"pos": [
12,
16
],
"name": "eyes"
} | {
"id": "C0042812",
"pos": [
41,
54
],
"name": "visual acuity"
} | 0NA |
The Response Surface Methodology ( RSM ) is applied to investigate the effect of three variables ( dye concentration , time and temperature ) and their interaction on the removal efficiency . | {
"id": "C0015252",
"pos": [
171,
178
],
"name": "removal"
} | {
"id": "C0005903",
"pos": [
128,
139
],
"name": "temperature"
} | 0NA |
Hypercalciuria induced by high levels of amino acid infusion during total parenteral nutrition may contribute to the development of metabolic bone disease . | {
"id": "C0002520",
"pos": [
41,
51
],
"name": "amino acid"
} | {
"id": "C0574032",
"pos": [
52,
60
],
"name": "infusion"
} | 0NA |
The morphologic appearance , in conjunction with the elevated IgG4 expression , distinguishes chronic sclerosing sialadenitis from other inflammatory diseases of the salivary glands . | {
"id": "C0036098",
"pos": [
166,
181
],
"name": "salivary glands"
} | {
"id": "C2826557",
"pos": [
94,
125
],
"name": "chronic sclerosing sialadenitis"
} | 11finding_site_of |
Other modalities of digital post-processing may be helpful to depict gingival soft tissues , with obvious advantages for the study of periodontal diseases . | {
"id": "C0017562",
"pos": [
69,
77
],
"name": "gingival"
} | {
"id": "C0031090",
"pos": [
134,
154
],
"name": "periodontal diseases"
} | 0NA |
The postmortem examination showed generalized arterial calcification , periarticular calcific deposits , and a large pleural hemorrhage . | {
"id": "C0031809",
"pos": [
15,
26
],
"name": "examination"
} | {
"id": "C0004398",
"pos": [
4,
14
],
"name": "postmortem"
} | 17method_of |
Epithelial to mesenchymal transition ( EMT ) of tubular cells contributes to the renal accumulation of matrix protein that is associated with diabetic nephropathy . | {
"id": "C0022646",
"pos": [
81,
86
],
"name": "renal"
} | {
"id": "C0011881",
"pos": [
142,
162
],
"name": "diabetic nephropathy"
} | 11finding_site_of |
The aim of this study was to describe the clinical characteristics and radiologic findings in patients with a previous history of malignancy who underwent computed tomography ( CT ) screening for lung cancer . | {
"id": "C0006826",
"pos": [
130,
140
],
"name": "malignancy"
} | {
"id": "C0199230",
"pos": [
182,
191
],
"name": "screening"
} | 12focus_of |
After the first day of treatment with dapsone 100 mg , rifampin 600 mg , and clofazimine 50 mg , the patient complained of burning and pain in his ankles and wrists . | {
"id": "C0030193",
"pos": [
135,
139
],
"name": "pain"
} | {
"id": "C0010980",
"pos": [
38,
45
],
"name": "dapsone"
} | 0NA |
Funduscopic examinations and visual field testing with a red object must be included . | {
"id": "C0031809",
"pos": [
12,
24
],
"name": "examinations"
} | {
"id": "C0042825",
"pos": [
29,
49
],
"name": "visual field testing"
} | 17method_of |
On admission platelets were 110 x 10(9)/L without petechiae or purpura , and coronary angiography revealed multivessel disease with significant left main involvement . | {
"id": "C0184666",
"pos": [
3,
12
],
"name": "admission"
} | {
"id": "C0031256",
"pos": [
50,
59
],
"name": "petechiae"
} | 0NA |
The method suggested has been demonstrated to be informative in the diagnosis of hydrocephalus and sizable injuries to the brain during mass screenings . | {
"id": "C0006104",
"pos": [
123,
128
],
"name": "brain"
} | {
"id": "C0020255",
"pos": [
81,
94
],
"name": "hydrocephalus"
} | 0NA |
Several studies have shown that pain and analgesia are frequently neglected in ICU . | {
"id": "C0030193",
"pos": [
32,
36
],
"name": "pain"
} | {
"id": "C0002766",
"pos": [
41,
50
],
"name": "analgesia"
} | 12focus_of |
In all other displaced fractures , the main objective is preservation of the head since the best functional results can generally be obtained with internal fixation . | {
"id": "C0016658",
"pos": [
23,
32
],
"name": "fractures"
} | {
"id": "C0016642",
"pos": [
147,
164
],
"name": "internal fixation"
} | 8direct_morphology_of |
Cefoperazone , cefoxitin , cefusulodin , cefmetazole , cefotaxime , 6059-S , FK749 , YM-09330 , carbenicillin , and cloxacillin were stable to this enzyme and possessed the function of competitive inhibition , as shown by their affinity for the beta-lactamase . | {
"id": "C0007557",
"pos": [
15,
24
],
"name": "cefoxitin"
} | {
"id": "C0006976",
"pos": [
96,
109
],
"name": "carbenicillin"
} | 0NA |
Therefore , phosphodiesterase 4 inhibitors might be a novel therapeutic option for the prevention and/or management of acute PYN . | {
"id": "C0199176",
"pos": [
87,
97
],
"name": "prevention"
} | {
"id": "C2936609",
"pos": [
12,
42
],
"name": "phosphodiesterase 4 inhibitors"
} | 0NA |
Thus , CMHX008 showed insulin-sensitizing effects similar to those of rosiglitazone with a lower risk of bone loss , suggesting that PPARγ sparing eliminates the skeletal side effects of TZDs while maintaining their insulin-sensitizing properties . | {
"id": "C0037253",
"pos": [
162,
170
],
"name": "skeletal"
} | {
"id": "C0029453",
"pos": [
105,
114
],
"name": "bone loss"
} | 0NA |
It was found that the GSLs offered more sensitive detection limits when directly compared with antibodies . | {
"id": "C0003241",
"pos": [
95,
105
],
"name": "antibodies"
} | {
"id": "C0020517",
"pos": [
40,
49
],
"name": "sensitive"
} | 0NA |
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