text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Improving the COC for patients with type 2 diabetes may result in higher medication adherence and better health care outcomes . | {
"id": "C0013227",
"pos": [
73,
83
],
"name": "medication"
} | {
"id": "C0011860",
"pos": [
36,
51
],
"name": "type 2 diabetes"
} | 0NA |
In most brain regions , [125I]-alphaBTX binding was localized to neuronal cell bodies similar in morphology to those that exhibited alpha7 hybridization , suggesting that the high-affinity [125I]-alphaBTX binding sites in the human brain are likely to be principally composed of alpha7 receptor subtypes . | {
"id": "C0006104",
"pos": [
232,
237
],
"name": "brain"
} | {
"id": "C1273723",
"pos": [
8,
21
],
"name": "brain regions"
} | 0NA |
An increase in size could therefore reduce the risk of lameness associated with excessive digit loading . | {
"id": "C0582802",
"pos": [
90,
95
],
"name": "digit"
} | {
"id": "C0311395",
"pos": [
55,
63
],
"name": "lameness"
} | 0NA |
Likewise , MTSS1 protein expression in normal bladder tissue was significantly higher than that in BUCC tissue . | {
"id": "C0005682",
"pos": [
46,
53
],
"name": "bladder"
} | {
"id": "C0040300",
"pos": [
104,
110
],
"name": "tissue"
} | 0NA |
The data also indicated that the site of the heat production underlying , in part , endotoxic fevers gradually shifts from brown fat so skeletal muscle during the first month of life . | {
"id": "C0242692",
"pos": [
136,
151
],
"name": "skeletal muscle"
} | {
"id": "C0006298",
"pos": [
123,
132
],
"name": "brown fat"
} | 0NA |
Significant differences in the sinus microbiomes between CRS and control samples were revealed using high-throughput 16S rRNA gene sequencing . | {
"id": "C0016169",
"pos": [
31,
36
],
"name": "sinus"
} | {
"id": "C0010278",
"pos": [
57,
60
],
"name": "CRS"
} | 0NA |
It is commonly accepted that Xanthogranulomatous lesion of the pancreas ( XGP ) is hardly distinguishable from pancreatic neoplasms . | {
"id": "C0030274",
"pos": [
63,
71
],
"name": "pancreas"
} | {
"id": "C0030297",
"pos": [
111,
131
],
"name": "pancreatic neoplasms"
} | 11finding_site_of |
Moreover , similar to our observations after PTH stimulation , the apparent abnormal cAMP effect did not result from an altered time course of enzyme activation or a rightward shift in the dose response . | {
"id": "C0205161",
"pos": [
76,
84
],
"name": "abnormal"
} | {
"id": "C1292856",
"pos": [
49,
60
],
"name": "stimulation"
} | 0NA |
Except for degeneration of the cerebral cortex ( neocortex ) , the disease was indistinguishable clinically and neurohistologically from scrapie . | {
"id": "C0011164",
"pos": [
11,
23
],
"name": "degeneration"
} | {
"id": "C0007776",
"pos": [
31,
46
],
"name": "cerebral cortex"
} | 0NA |
Plunging ranulas arise when a simple ranula extends beyond the floor of the mouth into the neck . | {
"id": "C0027530",
"pos": [
91,
95
],
"name": "neck"
} | {
"id": "C0026686",
"pos": [
37,
43
],
"name": "ranula"
} | 0NA |
Taken together , these data suggest that sustained exposure of platelets to very low plasmin doses leads to platelet activation and thus may contribute to thrombotic complications in vivo . | {
"id": "C0087086",
"pos": [
155,
165
],
"name": "thrombotic"
} | {
"id": "C0016016",
"pos": [
85,
92
],
"name": "plasmin"
} | 0NA |
Radionuclide subtraction technique and gray-scale echography were used to localize parathyroid lesions in 6 patients with primary hyperparathyroidism . | {
"id": "C0030518",
"pos": [
83,
94
],
"name": "parathyroid"
} | {
"id": "C0221002",
"pos": [
122,
149
],
"name": "primary hyperparathyroidism"
} | 11finding_site_of |
Sixty eight percent of the patients with aneurysms died during the first 9 days after hemorrhage . | {
"id": "C0002940",
"pos": [
41,
50
],
"name": "aneurysms"
} | {
"id": "C0019080",
"pos": [
86,
96
],
"name": "hemorrhage"
} | 0NA |
The clinical usefulness , as well as the advantages and limitations of DWI in the abdomen and pelvis , currently are under discussion . | {
"id": "C0030797",
"pos": [
94,
100
],
"name": "pelvis"
} | {
"id": "C0557061",
"pos": [
123,
133
],
"name": "discussion"
} | 0NA |
The rarely occurring anaplastic thyroid carcinoma represents a highly malignant tumour of old patients , causing local compression symptoms at an early stage of disorder . | {
"id": "C0006826",
"pos": [
70,
86
],
"name": "malignant tumour"
} | {
"id": "C0012634",
"pos": [
161,
169
],
"name": "disorder"
} | 0NA |
The clinical sensitivity and specificity for detecting drug use by analyzing sweat collected from human subjects following known doses of codeine ( 0 , 30 , and 60 mg orally ) or heroin ( 20 mg intravenously ) were 76 and 100 % , respectively . | {
"id": "C0038984",
"pos": [
77,
82
],
"name": "sweat"
} | {
"id": "C0226896",
"pos": [
167,
173
],
"name": "orally"
} | 0NA |
Importantly , half of the patients with ' early ' disease already had severe fibrosis or cirrhosis on liver histology and dismal outcome ( 45 % mortality at 10years ) . | {
"id": "C0016059",
"pos": [
77,
85
],
"name": "fibrosis"
} | {
"id": "C0023890",
"pos": [
89,
98
],
"name": "cirrhosis"
} | 0NA |
Using anaphase bridge formation as an indicator , exposure to MR imaging alone , gadopentetate dimeglumine alone , or a combination of the two under the conditions used in this experiment did not cause detectable unstable chromosomal damage . | {
"id": "C0024485",
"pos": [
62,
72
],
"name": "MR imaging"
} | {
"id": "C0060934",
"pos": [
81,
106
],
"name": "gadopentetate dimeglumine"
} | 0NA |
In addition , a vision for some quick , highly sensitive and advanced methods for lectin detection and identification for diagnostic and therapeutic of various diseases is also provided . | {
"id": "C0020517",
"pos": [
47,
56
],
"name": "sensitive"
} | {
"id": "C0042789",
"pos": [
16,
22
],
"name": "vision"
} | 0NA |
It has been found that the bones are most frequently invaded by kidney cancer , somewhat less frequently by breast cancer and the bronchus cancer and markedly more rarely by cancer of other organs . | {
"id": "C0262950",
"pos": [
27,
32
],
"name": "bones"
} | {
"id": "C0006142",
"pos": [
108,
121
],
"name": "breast cancer"
} | 0NA |
Electrolytes , total protein , albumin , creatinine , uric acid , a qualitative or quantitative measurement of urine protein were required for inclusion into the study . | {
"id": "C0001924",
"pos": [
31,
38
],
"name": "albumin"
} | {
"id": "C0262923",
"pos": [
111,
124
],
"name": "urine protein"
} | 0NA |
The Wilcoxon test for variables comparing bleeding rates before and after the procedure obtained significant difference ( Z = -6.9 , p < 0.01 ) . | {
"id": "C0019080",
"pos": [
42,
50
],
"name": "bleeding"
} | {
"id": "C0184661",
"pos": [
78,
87
],
"name": "procedure"
} | 0NA |
Since AMD has features of a chronic low-grade systemic inflammatory response , attention to the exact role of lutein in this disease has shifted from a local effect in the eye towards a possible systemic anti-inflammatory function . | {
"id": "C0015392",
"pos": [
172,
175
],
"name": "eye"
} | {
"id": "C0012634",
"pos": [
125,
132
],
"name": "disease"
} | 0NA |
MRI will be performed to assess global brain connectivity . | {
"id": "C0006104",
"pos": [
39,
44
],
"name": "brain"
} | {
"id": "C0024485",
"pos": [
0,
3
],
"name": "MRI"
} | 0NA |
The sample consisted of 1,000 children , 6 to 18 years of age , including 242 females and 758 males , from Ege University who were diagnosed with ADHD . | {
"id": "C0086287",
"pos": [
78,
85
],
"name": "females"
} | {
"id": "C1263846",
"pos": [
146,
150
],
"name": "ADHD"
} | 0NA |
Infants ' survival was independently associated to antenatal steroids , singleton pregnancy , temperature on admission and CRIB score . | {
"id": "C0184666",
"pos": [
109,
118
],
"name": "admission"
} | {
"id": "C0005903",
"pos": [
94,
105
],
"name": "temperature"
} | 0NA |
Weight , body mass index , and lifestyle behaviors assessed via health risk assessment at baseline and 1-year follow-up . | {
"id": "C0031809",
"pos": [
76,
86
],
"name": "assessment"
} | {
"id": "C0005910",
"pos": [
0,
6
],
"name": "Weight"
} | 0NA |
Topiroxostat 120 mg/day provides non-inferior serum urate reduction compared with allopurinol 200 mg/day and is well tolerated in Japanese hyperuricemic patients with or without gout . | {
"id": "C0018099",
"pos": [
178,
182
],
"name": "gout"
} | {
"id": "C0002144",
"pos": [
82,
93
],
"name": "allopurinol"
} | 0NA |
At the end of each dietary phase and of the test period , ultrasound measurements were taken at the 10th rib . | {
"id": "C0035561",
"pos": [
105,
108
],
"name": "rib"
} | {
"id": "C0025344",
"pos": [
49,
55
],
"name": "period"
} | 0NA |
The plasma concentration of glucose , creatinine , uric acid , bilirubin , cholesterol , insulin , HbA1c and ET-1 were measured . | {
"id": "C0017725",
"pos": [
28,
35
],
"name": "glucose"
} | {
"id": "C0005437",
"pos": [
63,
72
],
"name": "bilirubin"
} | 0NA |
Exact number of the discarded kidneys with small renal masses which can be used for kidney transplantation should be determined by large scale studies . | {
"id": "C0022646",
"pos": [
30,
37
],
"name": "kidneys"
} | {
"id": "C0022671",
"pos": [
84,
106
],
"name": "kidney transplantation"
} | 13indirect_procedure_site_of |
Ventilation-perfusion pulmonary scintigraphy was carried out in 30 patients with a verified diagnosis of extra-hospital pneumonia ( EHP ) and 10 healthy subjects ; ventilation-perfusion ratio ( V/Q ) , apex-basis ventilation and perfusion gradient , and the condition of alveolar-capillary permeability ( ACP ) were analyzed . | {
"id": "C0012634",
"pos": [
258,
267
],
"name": "condition"
} | {
"id": "C0035203",
"pos": [
213,
224
],
"name": "ventilation"
} | 0NA |
Pooled odds ratios ( ORs ) with 95 % confidence intervals ( 95 % CIs ) were calculated for the outcomes of stroke and wound haematoma among patients receiving or not receiving protamine after CEA . | {
"id": "C0007099",
"pos": [
65,
68
],
"name": "CIs"
} | {
"id": "C0281860",
"pos": [
118,
133
],
"name": "wound haematoma"
} | 0NA |
Stage 1 included : 1 ) forming an advisory group ; 2 ) searching for descriptions of interventions in trials ( CENTRAL database ) and general health literature ( Medline ) ; 3 ) developing a sampling strategy ; 4 ) screening the search results ; 5 ) developing a data extraction form ; and 6 ) extracting intervention data . | {
"id": "C0184661",
"pos": [
305,
317
],
"name": "intervention"
} | {
"id": "C0199230",
"pos": [
215,
224
],
"name": "screening"
} | 0NA |
Second harmonic imaging ( SHI ) is a new ultrasound technique that is able to detect microbubbles in the tissue vascular space . | {
"id": "C0041618",
"pos": [
41,
61
],
"name": "ultrasound technique"
} | {
"id": "C0040300",
"pos": [
105,
111
],
"name": "tissue"
} | 0NA |
Human and rodent dissociated fetal brain neuronal cultures were established in-vitro by culturing on a glass grid of 60 planar microelectrodes neurons under identical conditions . | {
"id": "C0006104",
"pos": [
35,
40
],
"name": "brain"
} | {
"id": "C0040284",
"pos": [
88,
97
],
"name": "culturing"
} | 0NA |
Biopsy was consistent with an unspecified salivary gland neoplasm . | {
"id": "C0005558",
"pos": [
0,
6
],
"name": "Biopsy"
} | {
"id": "C0036095",
"pos": [
42,
65
],
"name": "salivary gland neoplasm"
} | 0NA |
The cardiorespiratory effects of prototype mu ( morphine and beta-casomorphine 1 - 4 ) and delta ( D-Ala2-D-Leu5Enkephalin-DADLE ) opioid ligands were compared following microinjection into third and fourth ventricular spaces in conscious and anesthetized rats . | {
"id": "C1720436",
"pos": [
243,
255
],
"name": "anesthetized"
} | {
"id": "C0026549",
"pos": [
48,
56
],
"name": "morphine"
} | 0NA |
The effect of this medication in pregnant women with APL is being a safe and effective treatment only after the first trimester of pregnancy . | {
"id": "C0013227",
"pos": [
19,
29
],
"name": "medication"
} | {
"id": "C0023487",
"pos": [
53,
56
],
"name": "APL"
} | 0NA |
However , leptomeningeal heterotopias were found on the cortical surface in ethanol-exposed rats independently of whether or not they showed hydrocephalus . | {
"id": "C0001613",
"pos": [
56,
64
],
"name": "cortical"
} | {
"id": "C0228126",
"pos": [
10,
24
],
"name": "leptomeningeal"
} | 0NA |
Understanding how these processes are regulated is crucial for the development of potential therapies against debilitating skeletal muscle wasting diseases . | {
"id": "C0242692",
"pos": [
123,
138
],
"name": "skeletal muscle"
} | {
"id": "C0087111",
"pos": [
92,
101
],
"name": "therapies"
} | 0NA |
During operation , it was observed that all of the coronary cusps had become thickened and shortened . | {
"id": "C0205400",
"pos": [
77,
86
],
"name": "thickened"
} | {
"id": "C0543467",
"pos": [
7,
16
],
"name": "operation"
} | 0NA |
Laboratory testing for possible adverse effects of insecticidal proteins on non-target organisms ( NTOs ) is an important part of many ecological risk assessments for regulatory decision-making about the cultivation of insect-resistant genetically modified ( IRGM ) crops . | {
"id": "C1261322",
"pos": [
151,
162
],
"name": "assessments"
} | {
"id": "C0022885",
"pos": [
0,
18
],
"name": "Laboratory testing"
} | 17method_of |
In recent years there has been a debate about the validity of the various methods for fixing lung tissue for electron microscopy in a state that faithfully reflects the physiological conditions prevailing at the time of fixation . | {
"id": "C0185023",
"pos": [
220,
228
],
"name": "fixation"
} | {
"id": "C0026019",
"pos": [
109,
128
],
"name": "electron microscopy"
} | 0NA |
Cataract surgery had been performed in 9.4 % persons , including 3.0 % who had bilateral surgery for cataracts . | {
"id": "C0086543",
"pos": [
101,
110
],
"name": "cataracts"
} | {
"id": "C0007389",
"pos": [
0,
16
],
"name": "Cataract surgery"
} | 8direct_morphology_of |
The definition of NAFLD was based on clinical criteria : elevated alanine aminotransferase ( > 35 U/L ) and liver steatosis features on ultrasound imaging . | {
"id": "C0041618",
"pos": [
136,
154
],
"name": "ultrasound imaging"
} | {
"id": "C0400966",
"pos": [
18,
23
],
"name": "NAFLD"
} | 0NA |
Scratching is an essential and a skin specific behavior induced by itching , which is a common symptom of atopic dermatitis ( AD ) and other types of dermatitis . | {
"id": "C0011615",
"pos": [
106,
123
],
"name": "atopic dermatitis"
} | {
"id": "C0033774",
"pos": [
67,
74
],
"name": "itching"
} | 0NA |
During the first two weeks after admission nutritional status was assessed using weight index , triceps skinfold thickness , arm muscle circumference , serum albumin and transthyretin . | {
"id": "C0184666",
"pos": [
33,
42
],
"name": "admission"
} | {
"id": "C0392209",
"pos": [
43,
61
],
"name": "nutritional status"
} | 0NA |
TSH levels were measured by immunoassay in the serum of newborns 4 - 5 days after delivery , no signs of hypothyroidism were observed . | {
"id": "C0229671",
"pos": [
47,
52
],
"name": "serum"
} | {
"id": "C0011209",
"pos": [
82,
90
],
"name": "delivery"
} | 0NA |
Body weight gain during the 14 days after the operation was less in the band group than in the control group ( p<0.01 ) . | {
"id": "C0043094",
"pos": [
0,
16
],
"name": "Body weight gain"
} | {
"id": "C0543467",
"pos": [
46,
55
],
"name": "operation"
} | 0NA |
Statistical analyses using Fisher 's exact test , ANOVA , Kaplan-Meier estimates , and Cox regression models were performed to show differences in mortality ( in-hospital , 6-month , 1-year ) , complications , length of ICU and total hospital stay , discharge disposition , surgical intervention , and accompanying fractures between elderly patients with and without femur fractures . | {
"id": "C0016658",
"pos": [
315,
324
],
"name": "fractures"
} | {
"id": "C0015802",
"pos": [
367,
382
],
"name": "femur fractures"
} | 3associated_morphology_of |
Given the eruptive nature of her disease , the possibility of an underlying malignancy was entertained . | {
"id": "C0006826",
"pos": [
76,
86
],
"name": "malignancy"
} | {
"id": "C0012634",
"pos": [
33,
40
],
"name": "disease"
} | 0NA |
Active caspase-1 , IL-18 , and IL-1β , which are regulated by inflammasomes , were measured in lung homogenates in wild-type ( WT ) , ASC(-/- ) , and NLRP3(-/- ) mice , and phenotypical changes related to pulmonary hypertension and right ventricular remodeling were characterized after hypoxic exposure . | {
"id": "C0024109",
"pos": [
95,
99
],
"name": "lung"
} | {
"id": "C0242184",
"pos": [
286,
293
],
"name": "hypoxic"
} | 0NA |
Activating the immune system to eliminate cancer cells and produce clinically relevant responses has been a long-standing goal of cancer research . | {
"id": "C0020962",
"pos": [
15,
28
],
"name": "immune system"
} | {
"id": "C0006826",
"pos": [
130,
136
],
"name": "cancer"
} | 0NA |
Two intervention studies found a positive effect of a gluten-free diet on disease-related markers in patients with MS . | {
"id": "C1446409",
"pos": [
33,
41
],
"name": "positive"
} | {
"id": "C0344351",
"pos": [
54,
70
],
"name": "gluten-free diet"
} | 0NA |
Spontaneous intramedullary apoptosis was measured in bone marrow ( BM ) biopsies of 175 patients with myelodysplastic syndromes ( MDS ) using in situ end-labeling ( ISEL ) of fragmented DNA . | {
"id": "C0005953",
"pos": [
53,
64
],
"name": "bone marrow"
} | {
"id": "C3463824",
"pos": [
102,
127
],
"name": "myelodysplastic syndromes"
} | 11finding_site_of |
The fall in the MRSA infection rate in orthopaedic and traumatology wards can be explained by antibiotic policy but also by other infection control measures . | {
"id": "C0009450",
"pos": [
21,
30
],
"name": "infection"
} | {
"id": "C0085557",
"pos": [
130,
147
],
"name": "infection control"
} | 12focus_of |
During laparotomy for peritonitis the abdominal wall was found to be stiff and fibrotic , with massive adhesions to the intestine . | {
"id": "C0021853",
"pos": [
120,
129
],
"name": "intestine"
} | {
"id": "C0031154",
"pos": [
22,
33
],
"name": "peritonitis"
} | 0NA |
The MIB-1 antibody against a nuclear protein Ki-67 was used to study the proliferation of cells in the rabbit retinal transplants . | {
"id": "C0035298",
"pos": [
110,
117
],
"name": "retinal"
} | {
"id": "C0003241",
"pos": [
10,
18
],
"name": "antibody"
} | 0NA |
Our findings suggest that the applanation method of obtaining IOP values is preferable in infants with ROP because this method is less affected by technical error and the variable nature of premature infant sclera . | {
"id": "C0021294",
"pos": [
190,
206
],
"name": "premature infant"
} | {
"id": "C0035344",
"pos": [
103,
106
],
"name": "ROP"
} | 5cause_of |
She and her deceased elder brother had severe renal insufficiency soon after birth . | {
"id": "C0205082",
"pos": [
39,
45
],
"name": "severe"
} | {
"id": "C0005615",
"pos": [
77,
82
],
"name": "birth"
} | 0NA |
The predicted probability of a difficult birth by an average sire indicated that twice as many males as females are born with difficulty . | {
"id": "C1299586",
"pos": [
126,
136
],
"name": "difficulty"
} | {
"id": "C0005615",
"pos": [
41,
46
],
"name": "birth"
} | 0NA |
It can be speculated that the elevation of serum growth factors may be detrimental to prostate cancer progression into malignancy . | {
"id": "C0006826",
"pos": [
119,
129
],
"name": "malignancy"
} | {
"id": "C0376358",
"pos": [
86,
101
],
"name": "prostate cancer"
} | 0NA |
Group 1 contained 13 patients with smaller tumors prior to radiation ( FIGO Ib and IIa ) , and recurrent or persistent disease confined to the cervix and/or vaginal vault . | {
"id": "C0007874",
"pos": [
143,
149
],
"name": "cervix"
} | {
"id": "C0227794",
"pos": [
157,
170
],
"name": "vaginal vault"
} | 0NA |
This response did not alter with atropine , methysergide , phentolamine and propranolol but was inhibited by aspirin and Sc 19220 . | {
"id": "C0004057",
"pos": [
109,
116
],
"name": "aspirin"
} | {
"id": "C0033497",
"pos": [
76,
87
],
"name": "propranolol"
} | 0NA |
Heart rate variability analysis using 24-h Holter monitoring is frequently performed to assess the cardiovascular status of a patient . | {
"id": "C0007226",
"pos": [
99,
113
],
"name": "cardiovascular"
} | {
"id": "C0018810",
"pos": [
0,
10
],
"name": "Heart rate"
} | 0NA |
Timothy syndrome ( TS ) is an autosomal dominant condition with the constellation of features including prolonged QT interval , hand and foot abnormalities , and mental retardation or autism . | {
"id": "C0012634",
"pos": [
49,
58
],
"name": "condition"
} | {
"id": "C1832916",
"pos": [
0,
16
],
"name": "Timothy syndrome"
} | 0NA |
While Ni has been considered an essential mineral for plants there is a clear lack of knowledge of its involvement in metabolic steps except the urease-catalyzed conversion of urea to ammonia and bicarbonate . | {
"id": "C0005367",
"pos": [
196,
207
],
"name": "bicarbonate"
} | {
"id": "C0041942",
"pos": [
176,
180
],
"name": "urea"
} | 0NA |
The dilatation and evacuation procedure was explored in 1971 as an alternative method of second-trimester abortion . | {
"id": "C1282573",
"pos": [
19,
39
],
"name": "evacuation procedure"
} | {
"id": "C0002940",
"pos": [
4,
14
],
"name": "dilatation"
} | 0NA |
The systemic response to ischemic stroke is associated with the hepatic acute phase response ( APR ) that modulates leukocytes recruitment to the injured brain . | {
"id": "C0006104",
"pos": [
154,
159
],
"name": "brain"
} | {
"id": "C0948008",
"pos": [
25,
40
],
"name": "ischemic stroke"
} | 11finding_site_of |
This might be due to insufficient maintenance immunosuppression - which always consists of two to three drugs with different mechanisms of action . | {
"id": "C0013227",
"pos": [
104,
109
],
"name": "drugs"
} | {
"id": "C0021079",
"pos": [
46,
63
],
"name": "immunosuppression"
} | 0NA |
We investigated residual brain damage in subjects who suffered severe traumatic brain injury ( TBI ) in childhood , and its relationship with declarative memory impairment . | {
"id": "C0006104",
"pos": [
25,
30
],
"name": "brain"
} | {
"id": "C0876926",
"pos": [
70,
92
],
"name": "traumatic brain injury"
} | 11finding_site_of |
The secretion of fluid and electrolytes by salivary gland acinar cells requires the coordinated regulation of multiple water and ion transporter and channel proteins . | {
"id": "C0036098",
"pos": [
43,
57
],
"name": "salivary gland"
} | {
"id": "C0427184",
"pos": [
84,
95
],
"name": "coordinated"
} | 0NA |
This is the first report of MRA visualizing abnormal vessels in this patient population . | {
"id": "C0205161",
"pos": [
44,
52
],
"name": "abnormal"
} | {
"id": "C0243032",
"pos": [
28,
31
],
"name": "MRA"
} | 0NA |
More attention is needed in the development and evaluation of such preventative approaches . | {
"id": "C0199176",
"pos": [
67,
79
],
"name": "preventative"
} | {
"id": "C0004268",
"pos": [
5,
14
],
"name": "attention"
} | 0NA |
The medical records of 23 consecutive individuals who were managed by intent to treat for head and neck cancer with metastatic disease in the lower neck nodes over a 19-year period were reviewed . | {
"id": "C0018670",
"pos": [
90,
94
],
"name": "head"
} | {
"id": "C0087111",
"pos": [
80,
85
],
"name": "treat"
} | 0NA |
Recently , we developed a series of G-quartet oligodeoxynucleotides ( GQ-ODN ) as novel and potent Stat3 inhibitors , which significantly suppressed the growth of prostate and breast tumors in nude mice . | {
"id": "C0033572",
"pos": [
163,
171
],
"name": "prostate"
} | {
"id": "C1458155",
"pos": [
176,
189
],
"name": "breast tumors"
} | 0NA |
Interaction of calf thymus non-histone chromosomal protein HMG2 with H1,H5-depleted nucleosomes from chicken erythrocytes was studied by means of thermal denaturation and an N-(3-pyrene)maleimide fluorescence probe . | {
"id": "C0230445",
"pos": [
15,
19
],
"name": "calf"
} | {
"id": "C0014772",
"pos": [
109,
121
],
"name": "erythrocytes"
} | 0NA |
The venous responses showed a gender difference because raloxifene was more potent in male veins . | {
"id": "C0042449",
"pos": [
91,
96
],
"name": "veins"
} | {
"id": "C0086582",
"pos": [
86,
90
],
"name": "male"
} | 0NA |
Faecal fistula was the most severe post-operative complication following simple closure of the perforation , causing death in all patients and leading to a 25 % mortality in those treated by this technique . | {
"id": "C0185003",
"pos": [
80,
87
],
"name": "closure"
} | {
"id": "C0333342",
"pos": [
0,
14
],
"name": "Faecal fistula"
} | 0NA |
However , the observation that bone resorption occurs in close proximity to microbial structures suggests that infection may be the most important trigger , often as a result of dental disease . | {
"id": "C0009450",
"pos": [
111,
120
],
"name": "infection"
} | {
"id": "C1704330",
"pos": [
178,
192
],
"name": "dental disease"
} | 0NA |
DVCT scans in the axial , coronal and sagittal planes of the sphenoid sinus of 384 patients were examined for evidence of sphenoid sinus agenesis and hypoplasia . | {
"id": "C0016169",
"pos": [
70,
75
],
"name": "sinus"
} | {
"id": "C0037884",
"pos": [
61,
69
],
"name": "sphenoid"
} | 0NA |
Parenteral nutrition ( PN ) was initiated soon after birth , and 14 ( 23 % ) patients had severe intestinal failure . | {
"id": "C0205082",
"pos": [
90,
96
],
"name": "severe"
} | {
"id": "C0005615",
"pos": [
53,
58
],
"name": "birth"
} | 0NA |
There was no evidence of cold agglutinins , cryoglobulins , syphilis , or other concurrent diseases in any of the patients . | {
"id": "C0012634",
"pos": [
91,
99
],
"name": "diseases"
} | {
"id": "C0039128",
"pos": [
60,
68
],
"name": "syphilis"
} | 0NA |
Patients were injected at the second lumbar ( L2 group ) or fourth lumbar ( L4 group ) vertebral body depending on the location of the pain syndrome in the lower extremity . | {
"id": "C0023216",
"pos": [
156,
171
],
"name": "lower extremity"
} | {
"id": "C0223084",
"pos": [
87,
101
],
"name": "vertebral body"
} | 0NA |
Similar reductions in the proportion of receptors binding agonist with a high affinity were seen after infusion of norepinephrine . | {
"id": "C0028351",
"pos": [
115,
129
],
"name": "norepinephrine"
} | {
"id": "C0574032",
"pos": [
103,
111
],
"name": "infusion"
} | 0NA |
One of its toxic effects is induction of oxidative stress ( mediated by the enzyme B(a)P hydroxylase ) which leads to various diseases like cancer . | {
"id": "C0006826",
"pos": [
140,
146
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
126,
134
],
"name": "diseases"
} | 0NA |
A successful one-stage repair of the clefts of the lower lip , tongue , and mandible was performed . | {
"id": "C0024687",
"pos": [
76,
84
],
"name": "mandible"
} | {
"id": "C0040408",
"pos": [
63,
69
],
"name": "tongue"
} | 0NA |
The quantity of bone can hardly be influenced after the 35th year of age , thus prevention of osteoporosis has special significance : appropriate calcium and vitamin D supplementation , weight-bearing sports and physical activity can prevent fractures . | {
"id": "C0016658",
"pos": [
242,
251
],
"name": "fractures"
} | {
"id": "C0029456",
"pos": [
94,
106
],
"name": "osteoporosis"
} | 0NA |
Obvious pathological changes of lung could be observed in silica-treated group , such as the thicken of interalveolar septum , which was infiltrated with lymphocytes , macrophages and a few neutrophils with the proliferation of fibroblasts and smooth muscle cells . | {
"id": "C0334094",
"pos": [
211,
224
],
"name": "proliferation"
} | {
"id": "C0024109",
"pos": [
32,
36
],
"name": "lung"
} | 0NA |
The more peripheral in the visual field the pattern is presented , the more sensitive the retina becomes . | {
"id": "C0035298",
"pos": [
90,
96
],
"name": "retina"
} | {
"id": "C0020517",
"pos": [
76,
85
],
"name": "sensitive"
} | 0NA |
The review will focus on the presentation of simple and repeatable methods of development of an adaptation stress to changed environmental conditions ( temperature , oxygenation , humidity ) and the technique of blood collection during hour-long estimation of interactions between the endocrine , nervous and immune systems . | {
"id": "C0020962",
"pos": [
309,
323
],
"name": "immune systems"
} | {
"id": "C0005903",
"pos": [
152,
163
],
"name": "temperature"
} | 0NA |
We report the first observation of echoes in the electric dipole moment of an ensemble of Rydberg atoms precessing in an external electric field F. Rapid reversal of the field direction is shown to play a role similar to that of a pi pulse in NMR in rephasing a dephased ensemble of electric dipoles resulting in the buildup of an echo . | {
"id": "C0024485",
"pos": [
243,
246
],
"name": "NMR"
} | {
"id": "C0034107",
"pos": [
234,
239
],
"name": "pulse"
} | 0NA |
High-definition optical coherence tomography ( HD-OCT ) is a non-invasive technique for morphological investigation of tissue with cellular resolution filling the imaging gap between reflectance confocal microscopy and conventional optical coherence tomography . | {
"id": "C0040300",
"pos": [
119,
125
],
"name": "tissue"
} | {
"id": "C0011923",
"pos": [
163,
170
],
"name": "imaging"
} | 0NA |
The patient did well after the procedure ; ascites resolved and liver function improved markedly . | {
"id": "C0184661",
"pos": [
31,
40
],
"name": "procedure"
} | {
"id": "C0003962",
"pos": [
43,
50
],
"name": "ascites"
} | 0NA |
Synovial sarcoma is an aggressive mesenchymal tumour , rarely occurring in the head and neck . | {
"id": "C0018670",
"pos": [
79,
83
],
"name": "head"
} | {
"id": "C0027530",
"pos": [
88,
92
],
"name": "neck"
} | 0NA |
Heart-rate response to the acceleratory stress was uneventful ; maximum heart rate occurred 3.2 s after the onset of LOC . | {
"id": "C0018810",
"pos": [
72,
82
],
"name": "heart rate"
} | {
"id": "C0234425",
"pos": [
117,
120
],
"name": "LOC"
} | 0NA |
There is currently insufficient evidence to recommend in-utero intervention for fetuses with CDH as a part of routine clinical practice . | {
"id": "C0235833",
"pos": [
93,
96
],
"name": "CDH"
} | {
"id": "C0184661",
"pos": [
63,
75
],
"name": "intervention"
} | 0NA |
In women with chronic hypertension in whom preeclampsia developed ( 13 pregnancies ) , blood pressure decreased and the renin-angiotensin-aldosterone system was stimulated in the first trimester as in the other groups . | {
"id": "C0032914",
"pos": [
43,
55
],
"name": "preeclampsia"
} | {
"id": "C0005823",
"pos": [
87,
101
],
"name": "blood pressure"
} | 15interprets |
Nifedipine was associated with significantly lower systolic blood pressure and a significantly higher incidence of edema . | {
"id": "C0013604",
"pos": [
115,
120
],
"name": "edema"
} | {
"id": "C0871470",
"pos": [
51,
74
],
"name": "systolic blood pressure"
} | 0NA |
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