text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
Mature ovarian teratoma is the most frequent benign tumor in premenopausal women . | {
"id": "C0086692",
"pos": [
45,
57
],
"name": "benign tumor"
} | {
"id": "C0280131",
"pos": [
7,
23
],
"name": "ovarian teratoma"
} | 0NA |
In this issue of Cell Metabolism , Thomas et al. ( 2009 ) show that specific activation of the bile-acid-activated G protein-coupled receptor TGR5 improves pancreatic and hepatic function and impairs the development of obesity following administration of a high-fat diet . | {
"id": "C0030274",
"pos": [
156,
166
],
"name": "pancreatic"
} | {
"id": "C0232741",
"pos": [
171,
187
],
"name": "hepatic function"
} | 0NA |
Pred treatment decreased cortical bone mineral content ( BMC ) , cortical thickness , stress/strain index and tissue volume of the mandible . | {
"id": "C0040300",
"pos": [
110,
116
],
"name": "tissue"
} | {
"id": "C0024687",
"pos": [
131,
139
],
"name": "mandible"
} | 0NA |
The Zone Diet was developed on the concept that the hormonal responses of macronutrients could be orchestrated to maintain key hormones within therapeutic zones to control inflammatory responses . | {
"id": "C0019932",
"pos": [
127,
135
],
"name": "hormones"
} | {
"id": "C0087111",
"pos": [
143,
154
],
"name": "therapeutic"
} | 0NA |
We describe the use of " SuperSelective " primers that enable the detection and quantitation of somatic mutations whose presence relates to cancer diagnosis , prognosis , and therapy , in real-time PCR assays that can potentially analyze rare DNA fragments present in blood samples ( liquid biopsies ) . | {
"id": "C0178913",
"pos": [
268,
281
],
"name": "blood samples"
} | {
"id": "C0033325",
"pos": [
159,
168
],
"name": "prognosis"
} | 0NA |
The pressor effect was not mediated by angiotensin II since pretreatment with an angiotensin antagonist failed to block the response . | {
"id": "C0028778",
"pos": [
114,
119
],
"name": "block"
} | {
"id": "C0003009",
"pos": [
39,
53
],
"name": "angiotensin II"
} | 0NA |
It is no less aggressive and dangerous than carcinoma of the posterior tongue . | {
"id": "C0226958",
"pos": [
61,
77
],
"name": "posterior tongue"
} | {
"id": "C0007097",
"pos": [
44,
53
],
"name": "carcinoma"
} | 0NA |
All patients were first operated on and successively irradiated at a dose of 45 - 50 Gy in 25 - 28 fractions for persistent ( n = 40 ) or recurrent ( n = 7 ) disease . | {
"id": "C0012634",
"pos": [
158,
165
],
"name": "disease"
} | {
"id": "C1522449",
"pos": [
53,
63
],
"name": "irradiated"
} | 0NA |
Authors introduce the case of a 64-year-old male patient with fulminant isolated necrotizing fasciitis of the chest wall , complicating empyema thoracis of unknown origin . | {
"id": "C0205076",
"pos": [
110,
120
],
"name": "chest wall"
} | {
"id": "C0014013",
"pos": [
136,
152
],
"name": "empyema thoracis"
} | 0NA |
Long-term potentiation of sympathetic ganglia ( gLTP ) , a unique form of synaptic plasticity , is serotonin dependent and can be blocked with 5-HT3 receptor antagonists . | {
"id": "C0028778",
"pos": [
130,
137
],
"name": "blocked"
} | {
"id": "C0017071",
"pos": [
26,
45
],
"name": "sympathetic ganglia"
} | 0NA |
Class IC agents ( flecainide or propafenone ) , which can be safely used in hospitalised patients with recent-onset AF without left ventricular dysfunction , can provide rapid conversion to sinus rhythm after either intravenous administration or oral loading . | {
"id": "C0226896",
"pos": [
246,
250
],
"name": "oral"
} | {
"id": "C0242698",
"pos": [
127,
155
],
"name": "left ventricular dysfunction"
} | 0NA |
It is concluded that a compound that lowers blood pressure and inhibits platelet activation may be of clinical benefit in the routine treatment of hypertension . | {
"id": "C0020538",
"pos": [
147,
159
],
"name": "hypertension"
} | {
"id": "C0005823",
"pos": [
44,
58
],
"name": "blood pressure"
} | 15interprets |
As a consequence of our interpretation of the findings and influenced by the high complication rate which we attribute to lymphadenectomy and the information given by other prognostic indicators , we have changed to a policy of carrying out pelvic external radiotherapy for all Stage II , grade 2 or 3 cases and those with deep myometrial invasion . | {
"id": "C0030797",
"pos": [
241,
247
],
"name": "pelvic"
} | {
"id": "C0024203",
"pos": [
122,
137
],
"name": "lymphadenectomy"
} | 0NA |
Thus , HrIL 1 beta administration produces pro- or anti-inflammatory effects on a developing polyarthritis depending on when treatment is started and is most effective as an anti-inflammatory molecule when started at the peak of the the inflammatory reaction , as previously described . | {
"id": "C0021368",
"pos": [
237,
258
],
"name": "inflammatory reaction"
} | {
"id": "C0162323",
"pos": [
93,
106
],
"name": "polyarthritis"
} | 3associated_morphology_of |
Two microdialysis probes were positioned in the subcutaneous fatty tissue and in the striated muscle of the parascapular region and perfused with Ringers ' solution . | {
"id": "C0242692",
"pos": [
85,
100
],
"name": "striated muscle"
} | {
"id": "C0222331",
"pos": [
48,
73
],
"name": "subcutaneous fatty tissue"
} | 0NA |
Logistical regression analysis showed that having multiple seizures in a 24-hour period was significantly predictive of abnormal EEG ( odds ratio , 2.98 ; 95 % confidence interval , 1.0 to 88 ; P=0.048 ) . | {
"id": "C0205161",
"pos": [
120,
128
],
"name": "abnormal"
} | {
"id": "C0013819",
"pos": [
129,
132
],
"name": "EEG"
} | 0NA |
The most common postoperative complications were neuromuscular pain ( n = 12 ) , hematoma ( n = 11 ) , urine leak ( n = 7 ) , and wound infection ( n = 7 ) . | {
"id": "C0018944",
"pos": [
81,
89
],
"name": "hematoma"
} | {
"id": "C0042024",
"pos": [
103,
113
],
"name": "urine leak"
} | 0NA |
The prevalence of blindness and moderate and severe visual impairment defined as presenting visual acuity was 1.48 % ( 75/5051 ) and 7.94 % ( 401/5051 ) respectively . | {
"id": "C0205082",
"pos": [
45,
51
],
"name": "severe"
} | {
"id": "C0042798",
"pos": [
52,
69
],
"name": "visual impairment"
} | 0NA |
The diagnostic and therapeutic potential of DB-ERCP is great , and the utility of the procedure could be further improved if customised accessories become more widely available . | {
"id": "C0184661",
"pos": [
86,
95
],
"name": "procedure"
} | {
"id": "C0087111",
"pos": [
19,
30
],
"name": "therapeutic"
} | 0NA |
The testing paradigm involved self-initiated trials ( a bar press ) , followed by 10-Hz stimulation at one of six locations ( e.g. , on the distal phalanx of the second toe on the left foot ) , providing the opportunity for the animal to press one of six buttons located on a facing panel . | {
"id": "C1292856",
"pos": [
88,
99
],
"name": "stimulation"
} | {
"id": "C0230461",
"pos": [
180,
189
],
"name": "left foot"
} | 0NA |
There were no significant differences in BMI , heart rate , systolic and diastolic blood pressure or lipid parameters between the groups . | {
"id": "C0023779",
"pos": [
101,
106
],
"name": "lipid"
} | {
"id": "C0018810",
"pos": [
47,
57
],
"name": "heart rate"
} | 0NA |
Because of the poor results of nonoperative management , internal fixation of these fractures is recommended in selected cases . | {
"id": "C0016658",
"pos": [
84,
93
],
"name": "fractures"
} | {
"id": "C0016642",
"pos": [
57,
74
],
"name": "internal fixation"
} | 8direct_morphology_of |
We will review the current recommendations of pneumothorax treatment and will highlight on the use of pigtail catheters in pneumothorax management in burn patients . | {
"id": "C0006434",
"pos": [
150,
154
],
"name": "burn"
} | {
"id": "C0032326",
"pos": [
46,
58
],
"name": "pneumothorax"
} | 0NA |
The objective of this research was to develop calcium-phosphate based thin coatings with antibacterial and bioactive properties for potential application in dental implants . | {
"id": "C0279516",
"pos": [
89,
102
],
"name": "antibacterial"
} | {
"id": "C0185125",
"pos": [
142,
153
],
"name": "application"
} | 0NA |
Taken together , our findings shed new light on the pathogenesis of osteopenia in MFS , in addition to arguing for a multifaceted treatment strategy in this congenital disorder of the connective tissue . | {
"id": "C0009780",
"pos": [
184,
201
],
"name": "connective tissue"
} | {
"id": "C0024796",
"pos": [
82,
85
],
"name": "MFS"
} | 11finding_site_of |
In CABG patients paired echocardiographic studies before and 6 months after revascularization classified dysfunctional myocardium as RDM or IRDM . | {
"id": "C0581603",
"pos": [
76,
93
],
"name": "revascularization"
} | {
"id": "C0010055",
"pos": [
3,
7
],
"name": "CABG"
} | 17method_of |
Diminished perfusion after reaming may delay healing or exacerbate existing injury to the cruciate ligaments and adversely affect rehabilitation of the knee after femoral fracture . | {
"id": "C0031001",
"pos": [
11,
20
],
"name": "perfusion"
} | {
"id": "C0022742",
"pos": [
152,
156
],
"name": "knee"
} | 0NA |
The purpose of the current anatomic illustration is to provide step-by-step techniques with fluoroscopic imaging to help confirm the safe placement of S2AI screws . | {
"id": "C0016356",
"pos": [
92,
112
],
"name": "fluoroscopic imaging"
} | {
"id": "C0021107",
"pos": [
138,
147
],
"name": "placement"
} | 0NA |
The incidences of hyperplasia of the thyroid gland C-cells ( 13/50 , 3/50 , 9/49 , 4/49 ) in 12,000 and 50,000 ppm males were significantly less than in the controls . | {
"id": "C0020507",
"pos": [
18,
29
],
"name": "hyperplasia"
} | {
"id": "C0086582",
"pos": [
115,
120
],
"name": "males"
} | 0NA |
Four hundred and nineteen maxillary and mandibular first and second molars ( 1457 canals ) were cleaned and shaped by two endodontists with new and used sets of nickel-titanium ProFile.04 taper rotary instruments . | {
"id": "C0024687",
"pos": [
40,
50
],
"name": "mandibular"
} | {
"id": "C0026367",
"pos": [
68,
74
],
"name": "molars"
} | 0NA |
Serum levels of the brain-originated proteins neuron-specific enolase ( NSE ) and protein S-100 , blood loss , transfusion requirements , adverse effects , and postoperative recovery profile were compared among the three groups . | {
"id": "C1880904",
"pos": [
46,
69
],
"name": "neuron-specific enolase"
} | {
"id": "C0202144",
"pos": [
72,
75
],
"name": "NSE"
} | 6component_of |
We found that the fla/che ( flagella and chemotaxis ) operon is positively regulated by unphosphorylated DegU. The effect was most prominent in a strain bearing the functional swrAA gene , a positive regulator of fla/che . | {
"id": "C1446409",
"pos": [
191,
199
],
"name": "positive"
} | {
"id": "C0080194",
"pos": [
146,
152
],
"name": "strain"
} | 0NA |
Stroke survivors might lose their walking and balancing abilities , but many studies pointed out that cycling is an effective means for lower limb rehabilitation . | {
"id": "C0034991",
"pos": [
147,
161
],
"name": "rehabilitation"
} | {
"id": "C0038454",
"pos": [
0,
6
],
"name": "Stroke"
} | 0NA |
We report two cases of haemoptysis occuring in ASA 1 otherwise healthy patients who underwent uncomplicated anaesthesia . | {
"id": "C0004057",
"pos": [
47,
50
],
"name": "ASA"
} | {
"id": "C0019079",
"pos": [
23,
34
],
"name": "haemoptysis"
} | 0NA |
S. aureus is occasionally occurring in the oral cavity in both health and disease in Sweden and Thailand . | {
"id": "C0226896",
"pos": [
43,
54
],
"name": "oral cavity"
} | {
"id": "C0012634",
"pos": [
74,
81
],
"name": "disease"
} | 0NA |
The effects of electronic noise on the imaging performance of HARP-AMFPI were modeled theoretically and system parameters were optimized for radiography and fluoroscopy . | {
"id": "C0016356",
"pos": [
157,
168
],
"name": "fluoroscopy"
} | {
"id": "C0011923",
"pos": [
39,
46
],
"name": "imaging"
} | 0NA |
Six hundred children were assigned to one of six regimens with PRP-T vaccine : full-dose , half-dose , and one-third-dose of Hib vaccine given separately or combined with diphtheria , tetanus , and pertussis ( DTP ) vaccine at ages 2 , 4 , and 6 months . | {
"id": "C0031237",
"pos": [
198,
207
],
"name": "pertussis"
} | {
"id": "C0012559",
"pos": [
210,
213
],
"name": "DTP"
} | 1active_ingredient_of |
The mean T4-T8 ratio was 2.3 in 18 ocular and in 16 nodal monoclonal B-cell proliferations , suggesting that the benign T cells in these proliferations represent a residual cell population rather than a distinctive subset originating in response to the B-cell neoplasm . | {
"id": "C0015392",
"pos": [
35,
41
],
"name": "ocular"
} | {
"id": "C0079731",
"pos": [
253,
268
],
"name": "B-cell neoplasm"
} | 0NA |
The aim of this study was to evaluate the effectiveness in dentin debris and smear layer removal from root canal walls using EDTA and QMix ® alone and also activated with Nd : YAG laser . | {
"id": "C0015252",
"pos": [
89,
96
],
"name": "removal"
} | {
"id": "C0011429",
"pos": [
59,
65
],
"name": "dentin"
} | 0NA |
Twenty uninjured , asymptomatic high school-aged pitchers underwent bilateral elbow MRI examinations . | {
"id": "C0031809",
"pos": [
88,
100
],
"name": "examinations"
} | {
"id": "C0024485",
"pos": [
84,
87
],
"name": "MRI"
} | 0NA |
Poor outcomes ( gangrene , amputation , or death ) were associated with a Mangled Extremity Severity Score > or = 6 ( p = 0.005 ) . | {
"id": "C0017086",
"pos": [
16,
24
],
"name": "gangrene"
} | {
"id": "C0002688",
"pos": [
27,
37
],
"name": "amputation"
} | 0NA |
The calibrated model provided good agreement with the nonlinear experimental loading curves , and can be used to further study the response of the cervical spine to various biomechanical investigations . | {
"id": "C0728985",
"pos": [
147,
161
],
"name": "cervical spine"
} | {
"id": "C1261322",
"pos": [
187,
201
],
"name": "investigations"
} | 0NA |
In Study 1 , 182 patients treated with chemotherapeutic regimens containing high dose cisplatin ( more than 70 mg/m2 ) were randomized to receive 24 mg of ondasentron intravenously ( i.v . ) or 3 mg of granisetron i.v . for the control of acute emesis . | {
"id": "C0008838",
"pos": [
86,
95
],
"name": "cisplatin"
} | {
"id": "C0042963",
"pos": [
245,
251
],
"name": "emesis"
} | 0NA |
The in vivo chronic effect of PECT NPs(Gel)confirmed no toxic lesions to animals in a whole period of three months even the dosage was high to 20 g/kg . | {
"id": "C0221198",
"pos": [
62,
69
],
"name": "lesions"
} | {
"id": "C0025344",
"pos": [
92,
98
],
"name": "period"
} | 0NA |
Almost half of the patients ( 48 % ) had a history of hypertension , more than a third ( 35 % ) had heart disease and about one fifth ( 18 % ) were diabetic . | {
"id": "C0020538",
"pos": [
54,
66
],
"name": "hypertension"
} | {
"id": "C0018799",
"pos": [
100,
113
],
"name": "heart disease"
} | 0NA |
Concomitant cholecystectomy adds minimal morbidity to the operation and should be performed unless specific contraindications exist . | {
"id": "C0008320",
"pos": [
12,
27
],
"name": "cholecystectomy"
} | {
"id": "C0543467",
"pos": [
58,
67
],
"name": "operation"
} | 0NA |
Tumor and normal tissue samples were frozen for enzymatic study . | {
"id": "C0027651",
"pos": [
0,
5
],
"name": "Tumor"
} | {
"id": "C0040300",
"pos": [
10,
23
],
"name": "normal tissue"
} | 0NA |
In the authors ' previous study of gallbladder function before and after fundoplication , 58 % of the patients demonstrated preoperative gallbladder motor dysfunction , and 86 % of those retested after operation and cessation of proton pump inhibitors ( PPIs ) normalized . | {
"id": "C0358591",
"pos": [
229,
251
],
"name": "proton pump inhibitors"
} | {
"id": "C0543467",
"pos": [
202,
211
],
"name": "operation"
} | 0NA |
Aspirin at doses of 30 and 60 mg/kg/dy significantly reduced tumour incidence . | {
"id": "C0027651",
"pos": [
61,
67
],
"name": "tumour"
} | {
"id": "C0004057",
"pos": [
0,
7
],
"name": "Aspirin"
} | 0NA |
Our confirmation of a strong association between trunk varices and grades 2 - 3 telangiectasia suggests the need for controlled studies into which condition should be treated . | {
"id": "C0042345",
"pos": [
55,
62
],
"name": "varices"
} | {
"id": "C0039446",
"pos": [
80,
94
],
"name": "telangiectasia"
} | 0NA |
Dermatologic manifestations are rare but , when found , are usually expressed as scalp ulcerations or blanching associated with gangrene of the tongue . | {
"id": "C0041582",
"pos": [
87,
98
],
"name": "ulcerations"
} | {
"id": "C0040408",
"pos": [
144,
150
],
"name": "tongue"
} | 0NA |
The results demonstrated that particle movement reduced the radius of influence ( ROI ) and the swept volume of injected air . | {
"id": "C0034627",
"pos": [
60,
66
],
"name": "radius"
} | {
"id": "C0026649",
"pos": [
39,
47
],
"name": "movement"
} | 0NA |
Because of the likelihood of cholelithiasis , the authors recommend that patients with biliary symptoms and ultrasonography findings suggesting polypoid lesions of the gallbladder undergo cholecystectomy . | {
"id": "C0016976",
"pos": [
168,
179
],
"name": "gallbladder"
} | {
"id": "C0008320",
"pos": [
188,
203
],
"name": "cholecystectomy"
} | 9direct_procedure_site_of |
The present study examined the motor effects of exogenous ATP on longitudinally-oriented preparations of the guinea-pig isolated ileum and the influence of drugs on the ATP-induced responses . | {
"id": "C0013227",
"pos": [
156,
161
],
"name": "drugs"
} | {
"id": "C0001480",
"pos": [
58,
61
],
"name": "ATP"
} | 0NA |
Based on a single-factor-at-a-time optimization strategy , the critical medium components were found to be glucose , urea , SrCl(2 ) and MgSO(4 ) . | {
"id": "C0017725",
"pos": [
107,
114
],
"name": "glucose"
} | {
"id": "C0041942",
"pos": [
117,
121
],
"name": "urea"
} | 0NA |
Previous or present infection with Shiga-like toxin producing E. coli ( SLTEC ) was detected by an indirect neutralization assay of antibody titer . | {
"id": "C0003241",
"pos": [
132,
140
],
"name": "antibody"
} | {
"id": "C0009450",
"pos": [
20,
29
],
"name": "infection"
} | 0NA |
Cancer is characterized as a condition with complex signs and symptoms . | {
"id": "C0006826",
"pos": [
0,
6
],
"name": "Cancer"
} | {
"id": "C0012634",
"pos": [
29,
38
],
"name": "condition"
} | 0NA |
A diagnosis of cerebral venous thrombosis with subarachnoid hemorrhage was made . | {
"id": "C0151945",
"pos": [
15,
41
],
"name": "cerebral venous thrombosis"
} | {
"id": "C0038525",
"pos": [
47,
70
],
"name": "subarachnoid hemorrhage"
} | 0NA |
Concentrations of NE and its intraneuronal metabolite dihydroxyphenylglycol ( DHPG ) in hearts , plasma , and coronary venous effluent were measured by high-performance liquid chromatography . | {
"id": "C0018787",
"pos": [
88,
94
],
"name": "hearts"
} | {
"id": "C0032105",
"pos": [
97,
103
],
"name": "plasma"
} | 0NA |
Thus , comparison of the results of a radionuclide study with morphological changes in the tuberculosis-afflicted pleura made it possible to establish the degree of pleural MCB impairments , to characterize the activity of a pathological process , and to define objectively treatment policy . | {
"id": "C0032225",
"pos": [
165,
172
],
"name": "pleural"
} | {
"id": "C0034606",
"pos": [
38,
56
],
"name": "radionuclide study"
} | 0NA |
The review gives information on the mechanisms which form the basis of hypertrophy and cardioprotective effect , as well as the role of alpha1-AR in maintaining the heart pump function in heart failure and cardiac adaptation to ischemia . | {
"id": "C0018787",
"pos": [
206,
213
],
"name": "cardiac"
} | {
"id": "C0018801",
"pos": [
188,
201
],
"name": "heart failure"
} | 11finding_site_of |
There exists an extensive and time-consuming surgical procedure which allows to remove the giant anorectal Buschke - Loewenstein tumors with good function of the anorectum and without the necessity of diverting stoma creation . | {
"id": "C0543467",
"pos": [
45,
63
],
"name": "surgical procedure"
} | {
"id": "C0441513",
"pos": [
217,
225
],
"name": "creation"
} | 0NA |
This problem is addressed by magnetization transfer contrast ( MTC ) enhancement , a MRI technique that generates high-contrast images based on characteristic tissue differences resulting from the interaction of water and macromolecules . | {
"id": "C0002475",
"pos": [
63,
66
],
"name": "MTC"
} | {
"id": "C0037420",
"pos": [
197,
208
],
"name": "interaction"
} | 0NA |
Downregulation of IGF‑1R had tumor suppressive roles similar to that of miR‑379 overexpression on NSCLC cell proliferation , migration and invasion . | {
"id": "C0027651",
"pos": [
29,
34
],
"name": "tumor"
} | {
"id": "C0007131",
"pos": [
98,
103
],
"name": "NSCLC"
} | 0NA |
Liver cancer in both sexes and lung cancer in women , which show increasing mortality rates , constitute a priority for prevention and further research . | {
"id": "C0199176",
"pos": [
120,
130
],
"name": "prevention"
} | {
"id": "C0242379",
"pos": [
31,
42
],
"name": "lung cancer"
} | 0NA |
Betamethasone 17-valerate , betamethasone 21-valerate and betamethasone were measured by a normal-phase high-performance liquid chromatographic ( HPLC ) method . | {
"id": "C0750848",
"pos": [
0,
25
],
"name": "Betamethasone 17-valerate"
} | {
"id": "C0005308",
"pos": [
58,
71
],
"name": "betamethasone"
} | 16is_modification_of |
Among current tobacco users , the intervention appeared to increase family rules regarding secondhand smoke exposure in their homes and vehicles . | {
"id": "C0184661",
"pos": [
34,
46
],
"name": "intervention"
} | {
"id": "C0274281",
"pos": [
108,
116
],
"name": "exposure"
} | 0NA |
After in vitro culture PPI were microencapsulated with highly purified barium-alginate and 1,000 mPPI of 300 - 500 microm Ø were transplanted under the left kidney capsule and/or into the peritoneal cavity of STZ-diabetic rats ( n = 15 ) without immunosuppression . | {
"id": "C0040732",
"pos": [
129,
141
],
"name": "transplanted"
} | {
"id": "C0021079",
"pos": [
246,
263
],
"name": "immunosuppression"
} | 0NA |
Increased risk of bleeding could be identified by significant elevated coagulation parameters ( TT and aPTT ) during dabigatran treatment . | {
"id": "C0019080",
"pos": [
18,
26
],
"name": "bleeding"
} | {
"id": "C0030605",
"pos": [
103,
107
],
"name": "aPTT"
} | 0NA |
Modern antituberculous therapy consists of a combination of several drugs , some of which ( e.g. rifampicin and streptomycin ) may cause impairment of renal function . | {
"id": "C0035608",
"pos": [
97,
107
],
"name": "rifampicin"
} | {
"id": "C0038425",
"pos": [
112,
124
],
"name": "streptomycin"
} | 0NA |
The highly conserved Phe and Gln residues at the sequential amino acid positions 220 - 221 in an upstream part of the putative substrate binding site were replaced with Ala and Glu , respectively . | {
"id": "C0002520",
"pos": [
60,
70
],
"name": "amino acid"
} | {
"id": "C0031453",
"pos": [
21,
24
],
"name": "Phe"
} | 0NA |
In contrast , there were pathological findings in 110 patients ( 79.7 % ): in 43.5 % a temporomandibular joint syndrome was diagnosed , in 29 % parafunction of the occlusion , and in 35 % a myopathy of the masticatory muscles . | {
"id": "C0001168",
"pos": [
164,
173
],
"name": "occlusion"
} | {
"id": "C0039496",
"pos": [
87,
119
],
"name": "temporomandibular joint syndrome"
} | 0NA |
The success of such nanoparticles as a therapeutic for diseases like cancer , however , depends heavily on the particles ' ability to localize to tumor tissue as well as provide minimal toxicity to surrounding tissues and key organs such as those involved in the reticuloendothelial system ( RES ) . | {
"id": "C0006826",
"pos": [
69,
75
],
"name": "cancer"
} | {
"id": "C0012634",
"pos": [
55,
63
],
"name": "diseases"
} | 0NA |
In this cohort , the most common findings at chest computed tomography were mediastinal and hilar lymphadenopathy ( 44 % ) , linear scarring ( 20 % ) , and nodules and bronchial wall thickening ( 16 % ) . | {
"id": "C0025066",
"pos": [
76,
87
],
"name": "mediastinal"
} | {
"id": "C0456973",
"pos": [
92,
113
],
"name": "hilar lymphadenopathy"
} | 0NA |
Giving the correct advice for malaria is particularly important . | {
"id": "C0150600",
"pos": [
19,
25
],
"name": "advice"
} | {
"id": "C0024530",
"pos": [
30,
37
],
"name": "malaria"
} | 0NA |
However , the mechanical deformation of proteins and nucleic acids may provide key insights for understanding the changes in cellular structure , response and function under force , and offer new opportunities for the diagnosis and treatment of disease . | {
"id": "C0028606",
"pos": [
53,
66
],
"name": "nucleic acids"
} | {
"id": "C0012634",
"pos": [
245,
252
],
"name": "disease"
} | 0NA |
A gene encoding enhanced green fluorescent protein ( EGFP ) was used as a reporter and two constructs were investigated , pEGFP-N1 ( a vector constructed with a CMV promoter followed by the EGFP gene ) and pGB562/GFP ( a mammary gland-specific expression vector with regulatory sequences from the goat beta-casein gene linked to EGFP ) . | {
"id": "C0006141",
"pos": [
221,
228
],
"name": "mammary"
} | {
"id": "C0010823",
"pos": [
161,
164
],
"name": "CMV"
} | 0NA |
In 15 of these patients detailed studies of glomerular and tubular function of the kidneys were performed . | {
"id": "C0022646",
"pos": [
83,
90
],
"name": "kidneys"
} | {
"id": "C0022663",
"pos": [
44,
54
],
"name": "glomerular"
} | 0NA |
The amiloride-sensitive epithelial sodium channel ( ENaC ) is implicated in the control of blood pressure as demonstrated by the analysis of two genetic diseases , Liddle 's syndrome and pseudohypoaldosteronism ( PHA-1 ) . | {
"id": "C0019247",
"pos": [
145,
161
],
"name": "genetic diseases"
} | {
"id": "C0005823",
"pos": [
91,
105
],
"name": "blood pressure"
} | 0NA |
The use of radiation therapy ( RT ) to treat adrenal tumors has historically been limited by the risk of normal tissue toxicity , given the proximity of the adrenals to radiosensitive structures , such as the kidney , stomach , intestine , and spinal cord . | {
"id": "C0001625",
"pos": [
157,
165
],
"name": "adrenals"
} | {
"id": "C0001624",
"pos": [
45,
59
],
"name": "adrenal tumors"
} | 11finding_site_of |
In 182 cases ( 93.4 % ) placement of the tube was successful without complications . | {
"id": "C0175730",
"pos": [
41,
45
],
"name": "tube"
} | {
"id": "C0021107",
"pos": [
24,
33
],
"name": "placement"
} | 0NA |
Lung involvement in inflammatory myopathies is well described in adults , involving mostly interstitial lung disease , aspiration pneumonia and alveolar hypoventilation . | {
"id": "C0024109",
"pos": [
0,
4
],
"name": "Lung"
} | {
"id": "C0032290",
"pos": [
119,
139
],
"name": "aspiration pneumonia"
} | 11finding_site_of |
The retraction pattern and histogram indices of VI provided by 3D ultrasound may be useful in predicting prognostic information about breast cancer . | {
"id": "C0332523",
"pos": [
4,
14
],
"name": "retraction"
} | {
"id": "C0006142",
"pos": [
134,
147
],
"name": "breast cancer"
} | 0NA |
This was demonstrated by our case of a 39-year-old woman with gastric mucosa associated lymphoid tissue lymphoma ( MALToma ) , stage III after chemotherapy . | {
"id": "C0017136",
"pos": [
62,
76
],
"name": "gastric mucosa"
} | {
"id": "C0013216",
"pos": [
143,
155
],
"name": "chemotherapy"
} | 0NA |
Then fructose-fed animals were randomly divided into four groups receiving water , Simiao pill ( 78.87 and 157.74 mg/kg ) and allopurinol ( 5mg/kg ) daily for next 6 weeks , respectively . | {
"id": "C0002144",
"pos": [
126,
137
],
"name": "allopurinol"
} | {
"id": "C0043047",
"pos": [
75,
80
],
"name": "water"
} | 0NA |
Stimulation by dexamethasone was continued for 48 hr . | {
"id": "C1292856",
"pos": [
0,
11
],
"name": "Stimulation"
} | {
"id": "C0011777",
"pos": [
15,
28
],
"name": "dexamethasone"
} | 0NA |
Despite the high rate of satisfactory outcomes , the response to PUVA therapy with respect to specific localization revealed poor response in eight out of 10 patients with vitiligo on the hands and feet . | {
"id": "C0016504",
"pos": [
198,
202
],
"name": "feet"
} | {
"id": "C0034172",
"pos": [
65,
77
],
"name": "PUVA therapy"
} | 0NA |
The Mauritius experience indicates that ongoing intervention , strong leadership , and substantial predictable funding are critical to consistently prevent the reestablishment of malaria . | {
"id": "C0024530",
"pos": [
179,
186
],
"name": "malaria"
} | {
"id": "C0184661",
"pos": [
48,
60
],
"name": "intervention"
} | 0NA |
These dramatic CA effects were nullified by preincubation of the drug either with L-cysteine or with beta-mercaptoethanol ; however , iodoacetamide ( 10(-6)M ) gave no such morphologic consequences . | {
"id": "C0013227",
"pos": [
65,
69
],
"name": "drug"
} | {
"id": "C0010654",
"pos": [
82,
92
],
"name": "L-cysteine"
} | 0NA |
Desmosomes are prominent cell-cell junctions found in a variety of tissues that resist mechanical stress , including the heart , and recruit the intermediate filament cytoskeleton to sites of cell-cell contact . | {
"id": "C0018787",
"pos": [
121,
126
],
"name": "heart"
} | {
"id": "C0040300",
"pos": [
67,
74
],
"name": "tissues"
} | 0NA |
In 39 eyes , the diagnosis was unequivocally tractional retinoschisis because the retinal elevation maintained its concave contour despite the development of retinal holes . | {
"id": "C0035298",
"pos": [
82,
89
],
"name": "retinal"
} | {
"id": "C0035321",
"pos": [
158,
171
],
"name": "retinal holes"
} | 11finding_site_of |
Antigen assays for the rapid diagnosis of invasive fungal infections are in development , and galactomannan and glucan are two such promising antigens . | {
"id": "C0003320",
"pos": [
142,
150
],
"name": "antigens"
} | {
"id": "C0430420",
"pos": [
0,
14
],
"name": "Antigen assays"
} | 6component_of |
Eye tracking offers a practical solution for monitoring cognitive performance in real world tasks . | {
"id": "C0015392",
"pos": [
0,
3
],
"name": "Eye"
} | {
"id": "C0150369",
"pos": [
45,
55
],
"name": "monitoring"
} | 0NA |
Importantly , in vivo we found that in bronchial mucosal biopsies from asthmatics the intensity of alpha-smooth muscle actin expression was strongly related to the number of mast cells within or adjacent to an airway smooth muscle bundle . | {
"id": "C0005558",
"pos": [
57,
65
],
"name": "biopsies"
} | {
"id": "C0004096",
"pos": [
71,
81
],
"name": "asthmatics"
} | 0NA |
During follow-up , patients with decreased left ventricular function had worse event-free survival , although 77 % were alive without infarction or bypass grafting at 4 years . | {
"id": "C0021308",
"pos": [
134,
144
],
"name": "infarction"
} | {
"id": "C0185098",
"pos": [
148,
163
],
"name": "bypass grafting"
} | 0NA |
We present two cases in which neurogenic TOS was elicited by vascular compression of the inferior portion of the brachial plexus . | {
"id": "C0006090",
"pos": [
113,
128
],
"name": "brachial plexus"
} | {
"id": "C0039984",
"pos": [
41,
44
],
"name": "TOS"
} | 0NA |
Most women had early stage disease ( 55.6 % T1 lesions , 72.8 % node negative ) ; 55.6 % had breast-conserving surgery , and the remaining had unilateral or bilateral mastectomy . | {
"id": "C0221198",
"pos": [
47,
54
],
"name": "lesions"
} | {
"id": "C0191877",
"pos": [
157,
177
],
"name": "bilateral mastectomy"
} | 0NA |
Main outcome measures at birth were incidence of prematurity , congenital malformations and neonatal infections . | {
"id": "C0000768",
"pos": [
63,
87
],
"name": "congenital malformations"
} | {
"id": "C0005615",
"pos": [
25,
30
],
"name": "birth"
} | 0NA |
Male CR subjects exhibited bilateral reductions in olfactory bulb volume and abnormal asymmetries of the posterior nasal cavities and olfactory sulci ( left reduced relative to right ) . | {
"id": "C0205161",
"pos": [
77,
85
],
"name": "abnormal"
} | {
"id": "C0228205",
"pos": [
134,
149
],
"name": "olfactory sulci"
} | 0NA |
This test involves using a blood sample to analyze the promoter region of the UGT1A1 gene ( UGT1A1 * 28 allele ) . | {
"id": "C0178913",
"pos": [
27,
39
],
"name": "blood sample"
} | {
"id": "C0022885",
"pos": [
5,
9
],
"name": "test"
} | 0NA |
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