text stringlengths 18 770 | h dict | t dict | relation class label 22
classes |
|---|---|---|---|
The CT attenuation and image noise for all reconstructions were calculated at the lung apex , middle , and base . | {
"id": "C0524865",
"pos": [
43,
58
],
"name": "reconstructions"
} | {
"id": "C0227972",
"pos": [
94,
100
],
"name": "middle"
} | 0NA |
Since intracanal medicaments can affect the cell viability in periapical tissues , the aim of this study was to evaluate the effect of calcium hydroxide and propolis on pulp fibroblasts . | {
"id": "C0011399",
"pos": [
169,
173
],
"name": "pulp"
} | {
"id": "C0031033",
"pos": [
62,
80
],
"name": "periapical tissues"
} | 0NA |
Similarly to other hitherto tested prostaglandins in humans , this new analogue exhibits its effect primarily through direct stimulatory effect on the uterine smooth muscle , resulting in subsequent decline in the concentrations of HCG , E2 , and progesterone . | {
"id": "C0033554",
"pos": [
35,
49
],
"name": "prostaglandins"
} | {
"id": "C0033308",
"pos": [
247,
259
],
"name": "progesterone"
} | 0NA |
Hypergonadotropic hypogonadism , azoospermia , short stature of postnatal onset ( -2 to -4 SD in adulthood ) , premature graying of hair , and dysmorphism were present in all patients . | {
"id": "C0018494",
"pos": [
132,
136
],
"name": "hair"
} | {
"id": "C0263498",
"pos": [
111,
128
],
"name": "premature graying"
} | 11finding_site_of |
ECREM , thus , appears to be an interesting complex to be investigated in order to find new drugs for cancer , metabolic , neuro-degenerative and inflammatory diseases therapy . | {
"id": "C0013227",
"pos": [
92,
97
],
"name": "drugs"
} | {
"id": "C0006826",
"pos": [
102,
108
],
"name": "cancer"
} | 0NA |
Fifty eyes of 50 patients with diagnosis of glaucoma that were candidate for AGV surgery were included . | {
"id": "C0015392",
"pos": [
6,
10
],
"name": "eyes"
} | {
"id": "C0017601",
"pos": [
44,
52
],
"name": "glaucoma"
} | 11finding_site_of |
The initial lesion was a localized nasal polyp apparently treated adequately with excision and radiotherapy . | {
"id": "C0221198",
"pos": [
12,
18
],
"name": "lesion"
} | {
"id": "C0015252",
"pos": [
82,
90
],
"name": "excision"
} | 0NA |
To evaluate a hybrid intensity modulated radiation therapy ( IMRT ) technique as a class solution for treatment of the intact breast . | {
"id": "C0006141",
"pos": [
126,
132
],
"name": "breast"
} | {
"id": "C1512814",
"pos": [
61,
65
],
"name": "IMRT"
} | 0NA |
In addition , 20 women of early pregnancy with artificial abortion were categorized into a control group , whose embryos were sonographically confirmed alive before surgery . | {
"id": "C2584946",
"pos": [
152,
157
],
"name": "alive"
} | {
"id": "C0392535",
"pos": [
47,
66
],
"name": "artificial abortion"
} | 0NA |
Seventy-one consecutive isolates were tested for genotypic resistance to isoniazid , rifampicin , streptomycin , and ethambutol by polymerase chain reaction-single strand conformation polymorphism analysis and automated sequencing of target regions . | {
"id": "C0035608",
"pos": [
85,
95
],
"name": "rifampicin"
} | {
"id": "C0038425",
"pos": [
98,
110
],
"name": "streptomycin"
} | 0NA |
One patient with suspected IgA nephropathy had no histological diagnosis established because of a lack of glomeruli in the biopsy specimen . | {
"id": "C0005558",
"pos": [
123,
129
],
"name": "biopsy"
} | {
"id": "C0017661",
"pos": [
27,
42
],
"name": "IgA nephropathy"
} | 0NA |
Thrombus aspiration may facilitate DS . | {
"id": "C0087086",
"pos": [
0,
8
],
"name": "Thrombus"
} | {
"id": "C0349707",
"pos": [
9,
19
],
"name": "aspiration"
} | 0NA |
To present preliminary results of a pilot project on the prevention of alcohol-associated problems in adolescents with acute alcohol intoxication . | {
"id": "C0199176",
"pos": [
57,
67
],
"name": "prevention"
} | {
"id": "C0001969",
"pos": [
119,
145
],
"name": "acute alcohol intoxication"
} | 0NA |
Thus liver transplantation corrects the metabolic abnormalities of three of the six urea cycle enzyme deficiencies , and presumably would correct all . | {
"id": "C0014442",
"pos": [
95,
101
],
"name": "enzyme"
} | {
"id": "C0023911",
"pos": [
5,
26
],
"name": "liver transplantation"
} | 0NA |
Therefore , fish breathe air using some other structure , such as the gut or mouth , the swimbladder , or the skin . | {
"id": "C0017189",
"pos": [
70,
73
],
"name": "gut"
} | {
"id": "C0444099",
"pos": [
110,
114
],
"name": "skin"
} | 0NA |
We herein report a case of HABA-associated unclassifiable interstitial pneumonia that improved with combined therapy with pirfenidone and erythromycin . | {
"id": "C0298067",
"pos": [
122,
133
],
"name": "pirfenidone"
} | {
"id": "C0014806",
"pos": [
138,
150
],
"name": "erythromycin"
} | 0NA |
Muscle spasticity of the upper extremity was slightly negatively correlated with shoulder PROM . | {
"id": "C1140618",
"pos": [
25,
40
],
"name": "upper extremity"
} | {
"id": "C0026838",
"pos": [
0,
17
],
"name": "Muscle spasticity"
} | 0NA |
From electron micrographs and light microscopy of histological sections we determined that C. mesnili spores grow within the intestinal epithelium where they establish themselves intercellularly . | {
"id": "C0021853",
"pos": [
125,
135
],
"name": "intestinal"
} | {
"id": "C0014609",
"pos": [
136,
146
],
"name": "epithelium"
} | 0NA |
During the last decade , prediction tools have emerged as essential tools allowing researchers to select a manageable list of epitope candidates to test from a larger peptide , protein , or even proteome . | {
"id": "C0022885",
"pos": [
148,
152
],
"name": "test"
} | {
"id": "C0033684",
"pos": [
177,
184
],
"name": "protein"
} | 0NA |
Thermal injury was evident in heated cells , regardless of the NaCl concentration in TSB growth medium . | {
"id": "C0037494",
"pos": [
63,
67
],
"name": "NaCl"
} | {
"id": "C0332685",
"pos": [
0,
14
],
"name": "Thermal injury"
} | 0NA |
Hypertension is the most common chronic disease and is the leading risk factor for death caused by stroke , myocardial infarction , and end-stage renal failure . | {
"id": "C0022661",
"pos": [
136,
159
],
"name": "end-stage renal failure"
} | {
"id": "C0027051",
"pos": [
108,
129
],
"name": "myocardial infarction"
} | 0NA |
Patients were referred with a syndrome of fever and splenomegaly ( 100 % ) , peripheral lymphadenopathy ( 90 % ) , hepatomegaly ( 70 % ) , severe weight loss ( 70 % ) , respiratory symptoms ( 65 % ) and oedema ( 55 % ) . | {
"id": "C0013604",
"pos": [
203,
209
],
"name": "oedema"
} | {
"id": "C0038002",
"pos": [
52,
64
],
"name": "splenomegaly"
} | 0NA |
Such mixed-activity drugs have a complex pharmacology limiting their therapeutic utility and requiring their removal prior to stimulation of the receptor with agonist . | {
"id": "C0015252",
"pos": [
109,
116
],
"name": "removal"
} | {
"id": "C0087111",
"pos": [
69,
80
],
"name": "therapeutic"
} | 0NA |
Thus 80 % of total fetal CO2 production resulted from direct oxidation of carbon atoms in glucose ; the " direct " glucose oxidation fraction was 0.46 + /- 0.04 . | {
"id": "C0017725",
"pos": [
90,
97
],
"name": "glucose"
} | {
"id": "C0007012",
"pos": [
25,
28
],
"name": "CO2"
} | 0NA |
In both the esophagus and the tongue there was a circadian rhythm in the mitotic index with the peak occurring during the first half of the diurnal phase and the trough occurring during the first half of the nocturnal phase . | {
"id": "C0040408",
"pos": [
30,
36
],
"name": "tongue"
} | {
"id": "C0014876",
"pos": [
12,
21
],
"name": "esophagus"
} | 0NA |
Peptidylarginine deiminase type II ( PAD 2 ) is the primary enzyme responsible for conversion of protein bound arginine to citrulline in the central nervous system . | {
"id": "C0033684",
"pos": [
97,
104
],
"name": "protein"
} | {
"id": "C0008864",
"pos": [
123,
133
],
"name": "citrulline"
} | 0NA |
The lower extremity was involved in 25 patients , and the upper extremity was involved in six . | {
"id": "C1140618",
"pos": [
58,
73
],
"name": "upper extremity"
} | {
"id": "C0023216",
"pos": [
4,
19
],
"name": "lower extremity"
} | 0NA |
In the preoperative evaluation , transesophageal echocardiography clearly demonstrated an injury involving of mitral regurgitation secondary to total rupture of a papillary muscle . | {
"id": "C0030352",
"pos": [
163,
179
],
"name": "papillary muscle"
} | {
"id": "C3263722",
"pos": [
90,
96
],
"name": "injury"
} | 0NA |
The median time to pump replacement was 428 days ( range 0 to 1,474 ) . | {
"id": "C0182537",
"pos": [
19,
23
],
"name": "pump"
} | {
"id": "C0035139",
"pos": [
24,
35
],
"name": "replacement"
} | 0NA |
The results showed that shoulder impingement occurred more commonly in the IMN group than with either ORPF ( OR , 0.13 ; 95 % CI , 0.03 - 0.37 ) or MIPO fixation ( OR , 0.08 ; 95 % CI , 0.00 - 0.69 ) . | {
"id": "C0185023",
"pos": [
153,
161
],
"name": "fixation"
} | {
"id": "C0376685",
"pos": [
24,
44
],
"name": "shoulder impingement"
} | 0NA |
Recurrence was defined as regrowth of fibrovascular tissue over the corneoscleral limbus onto clear cornea in the area of previous pterygium excision . | {
"id": "C0010031",
"pos": [
100,
106
],
"name": "cornea"
} | {
"id": "C0085376",
"pos": [
68,
88
],
"name": "corneoscleral limbus"
} | 0NA |
The small intestine is extremely sensitive to ischemia-reperfusion ( I/R ) injury and a range of microcirculatory disturbances contribute to tissue damage . | {
"id": "C0010957",
"pos": [
141,
154
],
"name": "tissue damage"
} | {
"id": "C3263722",
"pos": [
75,
81
],
"name": "injury"
} | 3associated_morphology_of |
In earlier studies using region-specific antisera , there was virtually always an overlap of serum PTH levels in hyperparathyroidism and hypercalcemia associated with malignancy . | {
"id": "C0229671",
"pos": [
93,
98
],
"name": "serum"
} | {
"id": "C0185027",
"pos": [
82,
89
],
"name": "overlap"
} | 0NA |
Computed tomography evaluation 9 months after surgery showed collateral circulation and suspected stricture of the vena cava with an absence of clinical effect . | {
"id": "C1261287",
"pos": [
98,
107
],
"name": "stricture"
} | {
"id": "C0040405",
"pos": [
0,
19
],
"name": "Computed tomography"
} | 0NA |
By using fluorescent markers and confocal microscopy , we present the developing lung as a dynamic structure with smooth muscle and neural tissue in a prime position to influence growth and development . | {
"id": "C0024109",
"pos": [
81,
85
],
"name": "lung"
} | {
"id": "C1267092",
"pos": [
114,
127
],
"name": "smooth muscle"
} | 0NA |
Previously , we observed that alloxan-induced in vitro cytotoxicity and apoptosis in an insulin secreting rat insulinoma , RIN , cells was prevented by prior exposure to prostaglandin ( PG ) E(1 ) , PGE(2 ) , PGI(2 ) , PGF(1)(alpha ) , and PGF(3)(alpha ) ( P<0.05 compared to alloxan ) , whereas thromboxane B(2 ) ( TXB(... | {
"id": "C0021641",
"pos": [
88,
95
],
"name": "insulin"
} | {
"id": "C0033554",
"pos": [
170,
183
],
"name": "prostaglandin"
} | 0NA |
Diffuse bilateral uveal melanocyte proliferation is a rare paraneoplastic syndrome causing severe visual impairment . | {
"id": "C0205082",
"pos": [
91,
97
],
"name": "severe"
} | {
"id": "C0042798",
"pos": [
98,
115
],
"name": "visual impairment"
} | 0NA |
After 7 days , sutures were removed and status of wound , periodontal health , and progress of healing was assessed . | {
"id": "C0043250",
"pos": [
50,
55
],
"name": "wound"
} | {
"id": "C0043240",
"pos": [
95,
102
],
"name": "healing"
} | 3associated_morphology_of |
In the normal tissue , there is an activity gradient from the ascending colon to the rectum for neutral and alkaline SMases but not for acidic SMase . | {
"id": "C0034896",
"pos": [
85,
91
],
"name": "rectum"
} | {
"id": "C0040300",
"pos": [
7,
20
],
"name": "normal tissue"
} | 0NA |
Three neonates , all girls , were presented immediately after birth with severe hypotonia . | {
"id": "C0205082",
"pos": [
73,
79
],
"name": "severe"
} | {
"id": "C0005615",
"pos": [
62,
67
],
"name": "birth"
} | 0NA |
Abnormally deficient noradrenergic , serotonergic and dopaminergic systems result in the abnormal modulation of ontogeny and function of the higher and lower nervous systems . | {
"id": "C0205161",
"pos": [
89,
97
],
"name": "abnormal"
} | {
"id": "C0027763",
"pos": [
158,
173
],
"name": "nervous systems"
} | 0NA |
The present case is interesting because a DOAC was effective in treating DIC due to an aortic aneurysm , whereas warfarin , another oral anticoagulant , was ineffective . | {
"id": "C0010927",
"pos": [
73,
76
],
"name": "DIC"
} | {
"id": "C0043031",
"pos": [
113,
121
],
"name": "warfarin"
} | 0NA |
In 16 cases of large Achilles tendon defects which can not be stretched straightly to calcaneus tuberosities , repair with sliding gastrocnemius musculocutaneous flaps ( 16 cm x 5 cm to 21 cm x 10 cm ) and insertion reconstruction of the tendon were performed . | {
"id": "C0039508",
"pos": [
238,
244
],
"name": "tendon"
} | {
"id": "C0043240",
"pos": [
111,
117
],
"name": "repair"
} | 0NA |
Acute , febrile , asymmetric , nondeforming , nonerosive polyarthritis of the small and large joints responsive to nonsteroidal antiinflammatory drug therapy was the most common clinical pattern of arthritis in HIV-positive patients . | {
"id": "C0022417",
"pos": [
94,
100
],
"name": "joints"
} | {
"id": "C0003864",
"pos": [
198,
207
],
"name": "arthritis"
} | 11finding_site_of |
The bioavailability of injected PPS is greater than oral , suggesting better delivery to difficult tissues such as bone and cartilage . | {
"id": "C0007301",
"pos": [
124,
133
],
"name": "cartilage"
} | {
"id": "C0265259",
"pos": [
32,
35
],
"name": "PPS"
} | 0NA |
In this case report , we describe an uncommon case of late type III endoleak due to complete detachment of the stent-graft main body segment from its suprarenal uncovered fixation stent . | {
"id": "C0185023",
"pos": [
171,
179
],
"name": "fixation"
} | {
"id": "C0038257",
"pos": [
180,
185
],
"name": "stent"
} | 0NA |
The right maxillary first molars were extracted and sites were allowed 1 month to heal . | {
"id": "C0185115",
"pos": [
38,
47
],
"name": "extracted"
} | {
"id": "C0043240",
"pos": [
82,
86
],
"name": "heal"
} | 0NA |
In contrast to METH , which induced pronounced deficits in dopaminergic neuronal markers , repeated doses of MDA or MDMA did not alter striatal tyrosine hydroxylase ( TH ) activities or reduce striatal dopamine concentrations . | {
"id": "C0115471",
"pos": [
116,
120
],
"name": "MDMA"
} | {
"id": "C0025611",
"pos": [
15,
19
],
"name": "METH"
} | 16is_modification_of |
Left ventricular ( LV ) remodeling following myocardial infarction ( MI ) is a complex process involving extracellular matrix degradation and fibrosis . | {
"id": "C0016059",
"pos": [
142,
150
],
"name": "fibrosis"
} | {
"id": "C0027051",
"pos": [
45,
66
],
"name": "myocardial infarction"
} | 0NA |
The accurate assessment of visual field function can provide valuable information on a range of visual disorders . | {
"id": "C0031809",
"pos": [
13,
23
],
"name": "assessment"
} | {
"id": "C0042790",
"pos": [
96,
112
],
"name": "visual disorders"
} | 0NA |
Secondary outcomes included mothers ' self-reported message comprehension and perceptions of daughters ' vulnerability to HPV infection , infection severity , vaccine efficacy , and obstacles to immunization . | {
"id": "C0020971",
"pos": [
195,
207
],
"name": "immunization"
} | {
"id": "C0042210",
"pos": [
159,
166
],
"name": "vaccine"
} | 0NA |
All of the patients tolerated the injection well and there were no serious complications related to the procedure . | {
"id": "C0184661",
"pos": [
104,
113
],
"name": "procedure"
} | {
"id": "C0021485",
"pos": [
34,
43
],
"name": "injection"
} | 0NA |
In vitro cytotoxicity test , attachment , and proliferation of rMDSCs on the SIS hydrogel were higher than those on tissue culture dishes . | {
"id": "C0185023",
"pos": [
29,
39
],
"name": "attachment"
} | {
"id": "C0201622",
"pos": [
9,
26
],
"name": "cytotoxicity test"
} | 0NA |
The root surfaces were then instrumented to remove all cementum and the wounds immediately closed by replacing and suturing the flaps just coronal to the cemento-enamel junction . | {
"id": "C0011343",
"pos": [
55,
63
],
"name": "cementum"
} | {
"id": "C0038925",
"pos": [
128,
133
],
"name": "flaps"
} | 0NA |
The essential agreement for erythromycin , ciprofloxacin and tetracycline were 90 % , 70 % and 15 % respectively . | {
"id": "C0008809",
"pos": [
43,
56
],
"name": "ciprofloxacin"
} | {
"id": "C0039644",
"pos": [
61,
73
],
"name": "tetracycline"
} | 0NA |
CAE completely inactivated hepatitis B surface antigen at the lowest concentration compared with various compounds including about 500 amino acid derivatives , sodium hypochlorite , 2,4,4'-trichloro-2'-hydroxydiphenyl ether , and some detergents . | {
"id": "C0040958",
"pos": [
182,
223
],
"name": "2,4,4'-trichloro-2'-hydroxydiphenyl ether"
} | {
"id": "C0037518",
"pos": [
160,
179
],
"name": "sodium hypochlorite"
} | 0NA |
The tip of the left ventral anlage adheres to the duodenum and stretches to form a ring . | {
"id": "C0013303",
"pos": [
50,
58
],
"name": "duodenum"
} | {
"id": "C0270814",
"pos": [
63,
72
],
"name": "stretches"
} | 0NA |
Forty-one women were recruited after delivery of a full-term singleton infant and randomly assigned to intervention or usual care groups . | {
"id": "C0184661",
"pos": [
103,
115
],
"name": "intervention"
} | {
"id": "C0011209",
"pos": [
37,
45
],
"name": "delivery"
} | 0NA |
Multicentre imaging studies of brain tumours ( and other tumour and brain studies ) can enable a large group of patients to be studied , yet they present challenging technical problems . | {
"id": "C0027651",
"pos": [
57,
63
],
"name": "tumour"
} | {
"id": "C0006118",
"pos": [
31,
44
],
"name": "brain tumours"
} | 3associated_morphology_of |
In the previous study , we have found that the endo-beta-xylosidase from Patinopecten had the attachment activities of glycosaminoglycan ( GAG ) chains to peptide . | {
"id": "C0185023",
"pos": [
94,
104
],
"name": "attachment"
} | {
"id": "C0030956",
"pos": [
155,
162
],
"name": "peptide"
} | 0NA |
Four hundred forty five injections were given over one year ( from 15 March 2007 to 15 March 2008 ) , for age-related macular degeneration , retinal vascular occlusion , diabetic retinopathy , neovascular glaucoma , and idiopathic macular choroidal neovascularization ; distributed as follows : 11.5 % Bevacizumab , 18.6... | {
"id": "C0035298",
"pos": [
141,
148
],
"name": "retinal"
} | {
"id": "C0011884",
"pos": [
170,
190
],
"name": "diabetic retinopathy"
} | 11finding_site_of |
In 47 adenomas a total of 50 abnormal stemlines were seen . | {
"id": "C0205161",
"pos": [
29,
37
],
"name": "abnormal"
} | {
"id": "C0001430",
"pos": [
6,
14
],
"name": "adenomas"
} | 0NA |
Small cerebral infarctions are common in elderly patients , but the association between the magnetic resonance imaging finding and neurologic dysfunction after coronary artery bypass grafting has not been evaluated . | {
"id": "C0024485",
"pos": [
92,
118
],
"name": "magnetic resonance imaging"
} | {
"id": "C0010055",
"pos": [
160,
191
],
"name": "coronary artery bypass grafting"
} | 0NA |
Saline infusion brought about minor changes in peripheral and left ovarian vein steroid levels ; however , episodic fluctuations occurred in the adrenal vein samples . | {
"id": "C0038317",
"pos": [
80,
87
],
"name": "steroid"
} | {
"id": "C0574032",
"pos": [
7,
15
],
"name": "infusion"
} | 0NA |
In these areas the connective tissue scaffolding of the alveolar septum was interrupted , and the thickness of the alveolar wall was reduced to that of a single or double layer of alveolar epithelium , devoid of basal laminae . | {
"id": "C0009780",
"pos": [
19,
36
],
"name": "connective tissue"
} | {
"id": "C0225694",
"pos": [
180,
199
],
"name": "alveolar epithelium"
} | 0NA |
SPA cholecystectomy seems feasible , but standardization , safety and the real benefits for patients need further assessment . | {
"id": "C0031809",
"pos": [
114,
124
],
"name": "assessment"
} | {
"id": "C0008320",
"pos": [
4,
19
],
"name": "cholecystectomy"
} | 0NA |
For patients diagnosed with HGPIN on extended initial core sampling , a repeat biopsy within the first year is unnecessary in the absence of other clinical indicators of cancer . | {
"id": "C0005558",
"pos": [
79,
85
],
"name": "biopsy"
} | {
"id": "C1168327",
"pos": [
28,
33
],
"name": "HGPIN"
} | 0NA |
In summary , the antidepressive efficacy of a combination of fluoxetine and amantadine given in suboptimal doses may be related to the negative immunoendocrine effects of these drugs . | {
"id": "C0013227",
"pos": [
177,
182
],
"name": "drugs"
} | {
"id": "C0002403",
"pos": [
76,
86
],
"name": "amantadine"
} | 0NA |
Thrombus formation was studied by two-dimensional echocardiography , and events of arterial embolism recorded . | {
"id": "C0087086",
"pos": [
0,
8
],
"name": "Thrombus"
} | {
"id": "C0549124",
"pos": [
83,
100
],
"name": "arterial embolism"
} | 0NA |
However , the incidence of cesarean section was not improved as expected and there was one instance of uterine hyperstimulation . | {
"id": "C0269842",
"pos": [
103,
127
],
"name": "uterine hyperstimulation"
} | {
"id": "C0007876",
"pos": [
27,
43
],
"name": "cesarean section"
} | 0NA |
However , strains of C. neoformans vary widely in virulence and therefore in their ability to cause disease in humans . | {
"id": "C0012634",
"pos": [
100,
107
],
"name": "disease"
} | {
"id": "C0080194",
"pos": [
10,
17
],
"name": "strains"
} | 0NA |
These data are consistent with the hypothesis that multiple PG systems are activated during the acute-phase response , which may explain the dissociation between mechanisms controlling the behavioral and physiological responses to infection . | {
"id": "C0086168",
"pos": [
141,
153
],
"name": "dissociation"
} | {
"id": "C0009450",
"pos": [
231,
240
],
"name": "infection"
} | 0NA |
The neurological status and the main parameters ( arterial blood pressure , cardiac pulses , oxygen saturation , temperature ) must be monitored in all patients . | {
"id": "C1272641",
"pos": [
50,
73
],
"name": "arterial blood pressure"
} | {
"id": "C0005903",
"pos": [
113,
124
],
"name": "temperature"
} | 0NA |
RO 15 - 1788 ( 10 mg/kg ) , a drug that antagonises several effects of benzodiazepines but has little affinity for peripheral-type sites , had no action on the reduction in social interaction induced by RO 5 - 4864 . | {
"id": "C0013227",
"pos": [
30,
34
],
"name": "drug"
} | {
"id": "C0037420",
"pos": [
173,
191
],
"name": "social interaction"
} | 0NA |
Optical imaging of odorant responses in the cortex reveals that the piriform discards spatial segregation as well as chemotopy and returns to a highly distributed organization in which different odorants activate unique but dispersed ensembles of cortical neurons . | {
"id": "C0001613",
"pos": [
247,
255
],
"name": "cortical"
} | {
"id": "C0001614",
"pos": [
44,
50
],
"name": "cortex"
} | 11finding_site_of |
Atrophy of the medulla and spinal cord have specifically been described as suggestive of Alexander disease [ 1 ] . | {
"id": "C0333641",
"pos": [
0,
7
],
"name": "Atrophy"
} | {
"id": "C0270726",
"pos": [
89,
106
],
"name": "Alexander disease"
} | 0NA |
Vaginal leech infestation in postmenopausal woman can cause hypovolumic shock and severe anemia . | {
"id": "C0042232",
"pos": [
0,
7
],
"name": "Vaginal"
} | {
"id": "C0232970",
"pos": [
29,
43
],
"name": "postmenopausal"
} | 0NA |
The outcome of antifungal therapy depends on the progression of the infection at the start of therapy . | {
"id": "C0009450",
"pos": [
68,
77
],
"name": "infection"
} | {
"id": "C0678026",
"pos": [
15,
33
],
"name": "antifungal therapy"
} | 0NA |
Lipomas are benign tumors consisting of mature fat cells . | {
"id": "C0086692",
"pos": [
12,
25
],
"name": "benign tumors"
} | {
"id": "C0023798",
"pos": [
0,
7
],
"name": "Lipomas"
} | 0NA |
A few to large number of CAB-immunoreactive nerve fibers were seen in smooth muscles as well as in submucous and myenteric ganglia and they were regularly found around blood vessels . | {
"id": "C0005847",
"pos": [
168,
181
],
"name": "blood vessels"
} | {
"id": "C1267092",
"pos": [
70,
84
],
"name": "smooth muscles"
} | 0NA |
Main outcome measures included successful rate of posterior vitreous detachment in vitrectomy , visual outcome , and related ocular complications . | {
"id": "C0015392",
"pos": [
125,
131
],
"name": "ocular"
} | {
"id": "C0042907",
"pos": [
60,
79
],
"name": "vitreous detachment"
} | 0NA |
Recent data have shown that the risk of bleeding on dual antiplatelet therapy and oral anticoagulation ( " triple therapy " ) is high , although the optimal strategy for patients with atrial fibrillation and coronary artery disease remains unclear . | {
"id": "C0019080",
"pos": [
40,
48
],
"name": "bleeding"
} | {
"id": "C0010054",
"pos": [
210,
233
],
"name": "coronary artery disease"
} | 0NA |
Here , we provide direct functional evidence for the influence of presynaptic PMCA2-mediated Ca2 + extrusion for short-term plasticity at cerebellar parallel fiber to Purkinje neuron synapses . | {
"id": "C0007765",
"pos": [
138,
148
],
"name": "cerebellar"
} | {
"id": "C0039062",
"pos": [
183,
191
],
"name": "synapses"
} | 0NA |
Assessments confirmed the more problematic physical and psychosocial issues of patients in the tertiary palliative care unit . | {
"id": "C1261322",
"pos": [
0,
11
],
"name": "Assessments"
} | {
"id": "C0031809",
"pos": [
43,
51
],
"name": "physical"
} | 17method_of |
Attention should be given to optimizing risk factor reduction and preventive treatment with angiotensin-converting enzyme inhibitors/angiotensin receptor blockers and β-blockers if LVSD is present . | {
"id": "C0199176",
"pos": [
66,
86
],
"name": "preventive treatment"
} | {
"id": "C0004268",
"pos": [
0,
9
],
"name": "Attention"
} | 0NA |
Although early alcoholic hepatitis and cirrhosis respond to abstinence and symptomatic therapy , available measures have little influence on functional and morphologic abnormalities in end-stage alcoholic liver disease . | {
"id": "C0023890",
"pos": [
39,
48
],
"name": "cirrhosis"
} | {
"id": "C0019187",
"pos": [
15,
34
],
"name": "alcoholic hepatitis"
} | 0NA |
Impairments in self-awareness contribute to disability in schizophrenia . | {
"id": "C0231170",
"pos": [
44,
54
],
"name": "disability"
} | {
"id": "C3146223",
"pos": [
15,
29
],
"name": "self-awareness"
} | 0NA |
The possibility of recommending the drug into malaria treatment schedules for individuals with known history of chloroquine-induced pruritus is discussed . | {
"id": "C0013227",
"pos": [
36,
40
],
"name": "drug"
} | {
"id": "C0024530",
"pos": [
46,
53
],
"name": "malaria"
} | 0NA |
These studies reveal that the magnitude of gut I/R-induced liver injury depends on the duration of ischemic period and animal species . | {
"id": "C0017189",
"pos": [
43,
46
],
"name": "gut"
} | {
"id": "C0160390",
"pos": [
59,
71
],
"name": "liver injury"
} | 0NA |
This study was carried out to test the hypothesis that caffeine accelerates emergence from anesthesia in humans . | {
"id": "C0002903",
"pos": [
91,
101
],
"name": "anesthesia"
} | {
"id": "C0006644",
"pos": [
55,
63
],
"name": "caffeine"
} | 0NA |
In revision surgery for abdominal complications after VPS , visualization of whole abdominal cavity is fundamental to address properly the problem and laparoscopic approach is valuable once it is safe , fast and much less invasive than laparotomy . | {
"id": "C0230168",
"pos": [
83,
99
],
"name": "abdominal cavity"
} | {
"id": "C0023038",
"pos": [
236,
246
],
"name": "laparotomy"
} | 9direct_procedure_site_of |
Our results identified CRAMP , the mouse homolog of hCAP-18 , as a potential self-antigen involved in the immune response to atherosclerosis in the ApoE(-/- ) mouse model . | {
"id": "C0003850",
"pos": [
125,
140
],
"name": "atherosclerosis"
} | {
"id": "C0026821",
"pos": [
23,
28
],
"name": "CRAMP"
} | 0NA |
Having delivered an SGA infant with MSAF was associated with decreased rates of induction of labor and increased rates of labor dystocia , delivery by cesarean section and fetal distress . | {
"id": "C0011209",
"pos": [
139,
147
],
"name": "delivery"
} | {
"id": "C0007876",
"pos": [
151,
167
],
"name": "cesarean section"
} | 17method_of |
In the present study , the death process of germ cells has been characterized by depleting both FSH and testosterone by administering two different potent GnRH antagonists , Cetrorelix and Acyline to both rats and mice . | {
"id": "C0023610",
"pos": [
155,
159
],
"name": "GnRH"
} | {
"id": "C0039601",
"pos": [
104,
116
],
"name": "testosterone"
} | 0NA |
Our goal was to use functional MRI ( fMRI ) to measure brain activation in response to olfactory stimuli . | {
"id": "C0006104",
"pos": [
55,
60
],
"name": "brain"
} | {
"id": "C0024485",
"pos": [
31,
34
],
"name": "MRI"
} | 0NA |
If we define as radical those lymphadenectomies that resect four or five nodal levels and specify structures preserved or additional nonlymphatic structures sacrificed , we allow for the possibility that some procedures may be both modified and extended . | {
"id": "C0015252",
"pos": [
53,
59
],
"name": "resect"
} | {
"id": "C0024203",
"pos": [
30,
47
],
"name": "lymphadenectomies"
} | 0NA |
There was no correlation between the opioid used at baseline and switch frequency , but numbers of cases receiving other opioids than fentanyl or morphine were low . | {
"id": "C0242402",
"pos": [
37,
43
],
"name": "opioid"
} | {
"id": "C0015846",
"pos": [
134,
142
],
"name": "fentanyl"
} | 0NA |
However , EC and SC showed heterogeneity in chemoresponses leading to COC variability of more than one titration step in 44.1 % ( CIS ) and 20 % of HNSCC ( DTX ) . | {
"id": "C0007099",
"pos": [
130,
133
],
"name": "CIS"
} | {
"id": "C1168401",
"pos": [
148,
153
],
"name": "HNSCC"
} | 0NA |
These data provide the first demonstration in vivo that activation of a protein phosphatase can inactivate I kappa B , and suggest one possible explanation for mechanism-based toxicities associated with FK-506 and CsA by demonstrating that these drugs can inhibit the calcineurin-dependent activation of a virtually ubiq... | {
"id": "C0013227",
"pos": [
246,
251
],
"name": "drugs"
} | {
"id": "C0010592",
"pos": [
214,
217
],
"name": "CsA"
} | 0NA |
A simple , efficient procedure for removing lactic acid and for reducing nonprotein nitrogen and ash in lactic acid whey has been developed . | {
"id": "C0184661",
"pos": [
21,
30
],
"name": "procedure"
} | {
"id": "C0064582",
"pos": [
44,
55
],
"name": "lactic acid"
} | 0NA |
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