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The ultrastructural change in rat kidneys was analyzed after intraperitoneal injection of oxalic acid .
{ "id": "C0022646", "pos": [ 34, 41 ], "name": "kidneys" }
{ "id": "C0069715", "pos": [ 90, 101 ], "name": "oxalic acid" }
0NA
We have used transcutaneous electrical nerve stimulation ( TENS ) to treat the acute pain of rib fractures .
{ "id": "C0040654", "pos": [ 13, 56 ], "name": "transcutaneous electrical nerve stimulation" }
{ "id": "C0014518", "pos": [ 59, 63 ], "name": "TENS" }
0NA
The oral delivery of peptidic drugs is problematic because of their degradation in the gastrointestinal tract and low absorption through the intestinal mucosa .
{ "id": "C0017189", "pos": [ 87, 109 ], "name": "gastrointestinal tract" }
{ "id": "C0021839", "pos": [ 141, 158 ], "name": "intestinal mucosa" }
0NA
The incidence of diabetes mellitus is projected to continue to increase worldwide over the next 20 years leading to increased costs in the management of the disease and its associated co-morbidities .
{ "id": "C0011849", "pos": [ 17, 34 ], "name": "diabetes mellitus" }
{ "id": "C0012634", "pos": [ 157, 164 ], "name": "disease" }
0NA
However , oral contraceptives are associated with an increased risk of venous and arterial thrombosis , through changes in blood coagulation and fibrinolysis .
{ "id": "C0042449", "pos": [ 71, 77 ], "name": "venous" }
{ "id": "C0151942", "pos": [ 82, 101 ], "name": "arterial thrombosis" }
0NA
Animals were killed and syrinx sizes were calculated from in vivo MRI and histological studies .
{ "id": "C0024485", "pos": [ 66, 69 ], "name": "MRI" }
{ "id": "C0039144", "pos": [ 24, 30 ], "name": "syrinx" }
0NA
Animal studies have shown a gender dimorphic response of the liver for various stresses such as ischemia/reperfusion , hemorrhage/resuscitation , hepatectomy , portal branch ligation , and endotoxemia .
{ "id": "C0023884", "pos": [ 61, 66 ], "name": "liver" }
{ "id": "C0019144", "pos": [ 146, 157 ], "name": "hepatectomy" }
9direct_procedure_site_of
The atypical coarctation of aorta is a very rare disease .
{ "id": "C0003483", "pos": [ 28, 33 ], "name": "aorta" }
{ "id": "C0003492", "pos": [ 13, 24 ], "name": "coarctation" }
11finding_site_of
SMS included information to maintain the desired FBG levels and next due date for FBG assessment .
{ "id": "C0031809", "pos": [ 86, 96 ], "name": "assessment" }
{ "id": "C0795864", "pos": [ 0, 3 ], "name": "SMS" }
0NA
Basic research is bringing a much-needed infusion of optimism and urgency to the clinical diagnosis and treatment of Alzheimer disease .
{ "id": "C0574032", "pos": [ 41, 49 ], "name": "infusion" }
{ "id": "C0002395", "pos": [ 117, 134 ], "name": "Alzheimer disease" }
0NA
Imaging or tissue biomarker evidence has been introduced into the core diagnostic pathway for Alzheimer 's disease ( AD ) .
{ "id": "C0040300", "pos": [ 11, 17 ], "name": "tissue" }
{ "id": "C0011923", "pos": [ 0, 7 ], "name": "Imaging" }
0NA
All subjects showed facial flushing ; 6 , friction between the thighs ; 5 , sweating ; 9 , sleeping after the event ; and 12 , disturbance on interruption .
{ "id": "C0039866", "pos": [ 63, 69 ], "name": "thighs" }
{ "id": "C0016382", "pos": [ 20, 35 ], "name": "facial flushing" }
0NA
This was based on a phase 2 study by Memorial Sloan-Kettering Cancer Center ( MSKCC ) ; induction chemotherapy with rituximab , methotrexate , procarbazine , and vincristine ( R-MPV ) ( five to seven cycles ) , followed by whole-brain radiotherapy ( rd-WBRT ) ( 23.4 Gy ) and two high-dose cytarabine ( HD-AC ) cycles as a consolidation .
{ "id": "C0013216", "pos": [ 98, 110 ], "name": "chemotherapy" }
{ "id": "C0033223", "pos": [ 143, 155 ], "name": "procarbazine" }
0NA
The patients in type I were treated by extensive debridement and the flaps were used for free full and split thickness skin grafting .
{ "id": "C0037297", "pos": [ 119, 132 ], "name": "skin grafting" }
{ "id": "C0038925", "pos": [ 69, 74 ], "name": "flaps" }
0NA
Treatment of AGS cells with ferric nitrilotriacetate solution downregulated hepcidin expression levels , while desferroxamine , interleukin 6 and Helicobacter pylori infection upregulated it .
{ "id": "C0021760", "pos": [ 128, 141 ], "name": "interleukin 6" }
{ "id": "C0850666", "pos": [ 146, 175 ], "name": "Helicobacter pylori infection" }
0NA
In none of the cases , there was a significant effect of standard metal surgical tools ( clamps , tweezers , aspirators ) located near the patient 's head on the navigation system .
{ "id": "C0018670", "pos": [ 150, 154 ], "name": "head" }
{ "id": "C0475806", "pos": [ 130, 134 ], "name": "near" }
0NA
Results showed that emotion decreased the proportion of normatively correct responses only in the irrelevant condition .
{ "id": "C0012634", "pos": [ 109, 118 ], "name": "condition" }
{ "id": "C0013987", "pos": [ 20, 27 ], "name": "emotion" }
0NA
In this analytical cross-sectional study , a total of 202 consecutive patients who were candidates for diagnostic coronary angiography were randomized to undergo the procedure via TFA or TRA approaches ( 101 in each group ) .
{ "id": "C0040845", "pos": [ 187, 190 ], "name": "TRA" }
{ "id": "C0184661", "pos": [ 166, 175 ], "name": "procedure" }
0NA
The incidence of stroke and myocardial infarction is exceedingly low among women who use OCs containing 35 mcg or less of ethinyl estradiol , and formulations containing under 50 mcg of estrogen account for almost all current use in the US .
{ "id": "C0015011", "pos": [ 122, 139 ], "name": "ethinyl estradiol" }
{ "id": "C0014939", "pos": [ 186, 194 ], "name": "estrogen" }
0NA
The non-stratified analysis evidenced a significant association between vitiligo and several comorbid diseases , including alopecia areata , Hashimoto thyroiditis , myasthenia gravis , psoriasis , Graves ' disease , Sjögren 's syndrome , systemic lupus erythematosus and atopic dermatitis .
{ "id": "C0024141", "pos": [ 238, 266 ], "name": "systemic lupus erythematosus" }
{ "id": "C0026896", "pos": [ 165, 182 ], "name": "myasthenia gravis" }
0NA
We evaluated the medical records of patients who had previously undergone the designated surgeries for identification of postoperative delirium .
{ "id": "C0020792", "pos": [ 103, 117 ], "name": "identification" }
{ "id": "C0543467", "pos": [ 89, 98 ], "name": "surgeries" }
0NA
There are many difficulties in comparing the findings of existing studies of essential oil toxicity .
{ "id": "C1299586", "pos": [ 15, 27 ], "name": "difficulties" }
{ "id": "C0028910", "pos": [ 77, 90 ], "name": "essential oil" }
0NA
Although the acceptable effects were found in 3 groups , the better hearing threshold at high frequencies and lower incidence of complications can be obtained in patients with otosclerosis underwent small fenestra stapedotomy and stapes mobilization or elevation .
{ "id": "C0029899", "pos": [ 176, 188 ], "name": "otosclerosis" }
{ "id": "C0018767", "pos": [ 68, 75 ], "name": "hearing" }
0NA
Of the 160 polyps , 139 were confirmed by endoscopy , surgery , or repeat barium enema for a positive predictive value of 87 % .
{ "id": "C0032584", "pos": [ 11, 17 ], "name": "polyps" }
{ "id": "C0014245", "pos": [ 42, 51 ], "name": "endoscopy" }
0NA
Currently , the system sustains functioning hepatocytes for a minimum of 15 days ; confirmed by monitoring hepatic function ( urea , α-1-antitrypsin , fibrinogen , and cytochrome P450 ) and injury ( AST and ALT ) .
{ "id": "C0001899", "pos": [ 207, 210 ], "name": "ALT" }
{ "id": "C0150369", "pos": [ 96, 106 ], "name": "monitoring" }
0NA
The rotary door flap can provide an undelayed , one-stage epithelial resurfacing of the larynx and trachea while simultaneously restoring luminal support without the need for transfer of cartilage or bone .
{ "id": "C0040578", "pos": [ 99, 106 ], "name": "trachea" }
{ "id": "C0023078", "pos": [ 88, 94 ], "name": "larynx" }
0NA
Risk-eligible women are = 35 years of age and postmenopausal ; they have either lobular carcinoma in situ ( LCIS ) or a 5-year risk of invasive breast cancer of at least 1.67 % as determined by the Gail model .
{ "id": "C0206692", "pos": [ 80, 97 ], "name": "lobular carcinoma" }
{ "id": "C0232970", "pos": [ 46, 60 ], "name": "postmenopausal" }
0NA
Overall , 329 organs and 126 corneas were transplanted .
{ "id": "C0010031", "pos": [ 29, 36 ], "name": "corneas" }
{ "id": "C0040732", "pos": [ 42, 54 ], "name": "transplanted" }
0NA
The capacity of Healon5 to maintain the ACD during cataract surgery , ie , neutralizing the vitreous pressure and stabilizing the anterior segment of the eye , was significantly higher than that of the other OVDs .
{ "id": "C0015392", "pos": [ 154, 157 ], "name": "eye" }
{ "id": "C0007389", "pos": [ 51, 67 ], "name": "cataract surgery" }
0NA
Understanding brain functional alterations at early ages is important for understanding biological mechanisms of ASD .
{ "id": "C0006104", "pos": [ 14, 19 ], "name": "brain" }
{ "id": "C0018817", "pos": [ 113, 116 ], "name": "ASD" }
0NA
In the assessment of these disorders , anthropometry is limited by the lack of adequate reference values and by the difficulty or impossibility of measuring height using the conventional method .
{ "id": "C0031809", "pos": [ 7, 17 ], "name": "assessment" }
{ "id": "C0012634", "pos": [ 27, 36 ], "name": "disorders" }
0NA
Aspiration devices can persistently malfunction if moderate ( not just high ) suction causes mucosal occlusion of every opening .
{ "id": "C0349707", "pos": [ 0, 10 ], "name": "Aspiration" }
{ "id": "C0038638", "pos": [ 78, 85 ], "name": "suction" }
0NA
Taken together , these data suggest that commercially available fixatives greatly reduce , but do not eliminate the risk of HTLV-I infection during processing of viral-infected cells for FCM analysis .
{ "id": "C0016610", "pos": [ 187, 190 ], "name": "FCM" }
{ "id": "C0009450", "pos": [ 131, 140 ], "name": "infection" }
0NA
We also studied in both liver grafts the effects of Ang-II receptors antagonists and Ang-(1 - 7 ) receptor antagonists on hepatic I/R damage associated with transplantation .
{ "id": "C0010957", "pos": [ 134, 140 ], "name": "damage" }
{ "id": "C0040732", "pos": [ 157, 172 ], "name": "transplantation" }
0NA
Monthly hemoglobin , iron saturation , albumin , intact parathyroid hormone , calcium and phosphorus were unchanged after ERGO in these 2 groups .
{ "id": "C0001924", "pos": [ 39, 46 ], "name": "albumin" }
{ "id": "C0019046", "pos": [ 8, 18 ], "name": "hemoglobin" }
0NA
We report the first case of pancreas paraganglioma in Korea .
{ "id": "C0030274", "pos": [ 28, 36 ], "name": "pancreas" }
{ "id": "C0030421", "pos": [ 37, 50 ], "name": "paraganglioma" }
0NA
To our knowledge , this is only the second report of an adenomyoma of small intestine causing intestinal obstruction in an adult .
{ "id": "C0021852", "pos": [ 70, 85 ], "name": "small intestine" }
{ "id": "C0021843", "pos": [ 94, 116 ], "name": "intestinal obstruction" }
0NA
However , CT or MRI assessment of preoperative liver volume is associated with an estimation error of 1.2 % to 36 % , and little data is available on its accuracy on the segmental level .
{ "id": "C0031809", "pos": [ 20, 30 ], "name": "assessment" }
{ "id": "C0024485", "pos": [ 16, 19 ], "name": "MRI" }
0NA
DRPM distributed in pancreatic tissues sufficiently , and we could expect that DRPM was useful agent of pancreas infection in acute pancreatitis .
{ "id": "C0030274", "pos": [ 104, 112 ], "name": "pancreas" }
{ "id": "C0001339", "pos": [ 126, 144 ], "name": "acute pancreatitis" }
11finding_site_of
Evidence-based doses of statins , aspirin and angiotensin-converting enzyme inhibitors , or angiotensin II receptor blockers should be prescribed as adjuncts , not alternatives , to TLCs .
{ "id": "C0004057", "pos": [ 34, 41 ], "name": "aspirin" }
{ "id": "C0360714", "pos": [ 24, 31 ], "name": "statins" }
0NA
Fournier 's gangrene is a rare , fulminant , though generally localizaed disease of the scrotum and penis .
{ "id": "C0036471", "pos": [ 88, 95 ], "name": "scrotum" }
{ "id": "C0030851", "pos": [ 100, 105 ], "name": "penis" }
0NA
As a result , necrosis was seen following earlier rotation in the perforator group and viable flap areas were also lower .
{ "id": "C0027540", "pos": [ 14, 22 ], "name": "necrosis" }
{ "id": "C0038925", "pos": [ 94, 98 ], "name": "flap" }
0NA
Eight weeks after allocated treatments , the heart was extracted and analyzed following echocardiography .
{ "id": "C0018787", "pos": [ 45, 50 ], "name": "heart" }
{ "id": "C0013516", "pos": [ 88, 104 ], "name": "echocardiography" }
9direct_procedure_site_of
Brain biopsies or postmortem histopathological examination show evidence of astrogliosis , neuronal loss , degeneration of dendrites , demyelination , neurofibrillary tangles , and infiltration of inflammatory cells .
{ "id": "C0031809", "pos": [ 47, 58 ], "name": "examination" }
{ "id": "C0004398", "pos": [ 18, 28 ], "name": "postmortem" }
17method_of
The paper describes a postmortem observation of primary cardiovascular AL-amyloidosis first diagnosed by rectal biopsy in a 71-year-old woman .
{ "id": "C0007226", "pos": [ 56, 70 ], "name": "cardiovascular" }
{ "id": "C0004398", "pos": [ 22, 32 ], "name": "postmortem" }
0NA
A follow-up EEG 6 days after initiation of treatment with acyclovir showed a normal symmetrical background rhythm of 8 to 8.5 Hz , wherein the theta waves were significantly reduced in abundance , and the amplitude asymmetry was unchanged .
{ "id": "C0001367", "pos": [ 58, 67 ], "name": "acyclovir" }
{ "id": "C0013819", "pos": [ 12, 15 ], "name": "EEG" }
0NA
All cells were stimulated with a bar of near-optimal orientation , color , and dimensions while continuously monitoring the eye movements of fixation .
{ "id": "C0015392", "pos": [ 124, 127 ], "name": "eye" }
{ "id": "C0185023", "pos": [ 141, 149 ], "name": "fixation" }
0NA
The microbiological success rate against MRSA at the TOC visit was 56.4   % ( 95   % CI , 42.3 - 69.7 ) with daptomycin and 47.4   % ( 95   % CI , 24.4 - 71.1 ) with vancomycin .
{ "id": "C0042313", "pos": [ 166, 176 ], "name": "vancomycin" }
{ "id": "C0343401", "pos": [ 41, 45 ], "name": "MRSA" }
0NA
Here , we performed a global scanning assessment of antihistamines ( AHs ) , a common class of medicines , in surface waters and effluents .
{ "id": "C0013227", "pos": [ 95, 104 ], "name": "medicines" }
{ "id": "C0205710", "pos": [ 69, 72 ], "name": "AHs" }
0NA
Blood and fallopian tubes were collected from 14 women with EP .
{ "id": "C0005767", "pos": [ 0, 5 ], "name": "Blood" }
{ "id": "C0015560", "pos": [ 10, 25 ], "name": "fallopian tubes" }
0NA
In this cross-sectional study , we measured blood pressure and oxygen desaturations index ( ODI ) by nocturnal pulse oximetry of 249 male workers aged 20 to 65 yr .
{ "id": "C0086582", "pos": [ 133, 137 ], "name": "male" }
{ "id": "C0005823", "pos": [ 44, 58 ], "name": "blood pressure" }
0NA
The techniques included ( 1 ) the Fulton and relative condition factors , ( 2 ) relative mass , ( 3 ) plasma indicators of nutritional status ( alkaline phosphatase , calcium , cholesterol , protein , triglycerides and glucose ) and ( 4 ) readings from a hand-held , microwave energy meter .
{ "id": "C0041004", "pos": [ 201, 214 ], "name": "triglycerides" }
{ "id": "C0017725", "pos": [ 219, 226 ], "name": "glucose" }
0NA
Intensely reactive nerve fibers are observed in cranial sensory as well as in sympathetic and parasympathetic ganglia and nerves .
{ "id": "C0027740", "pos": [ 122, 128 ], "name": "nerves" }
{ "id": "C0017069", "pos": [ 94, 117 ], "name": "parasympathetic ganglia" }
0NA
Conventional US should be integrated by color Doppler , which shows parenchymal perfusion and patency of veins and arteries , and by spectral Doppler , which is crucial for the diagnosis of renal artery stenosis and provides important information about intrarenal microcirculation .
{ "id": "C0003842", "pos": [ 115, 123 ], "name": "arteries" }
{ "id": "C0042449", "pos": [ 105, 110 ], "name": "veins" }
0NA
In order to evaluate the seric prevalence of Coxiella burnetii , 100 serum samples that were taken from the adult population of Lanzarote and , following strict criteria , were analysed using a complement fixation test ; blood donors and patients who had suffered a recent infection were excluded .
{ "id": "C0009450", "pos": [ 273, 282 ], "name": "infection" }
{ "id": "C0009541", "pos": [ 194, 218 ], "name": "complement fixation test" }
0NA
The dexamethasone-induced PGE2 output of arachidonate-stimulated cells was blocked by the protein kinase inhibitors staurosporine , K-252a , H7 , HA1004 , and sphinganine , in a manner consistent with their effect on PKC .
{ "id": "C0028778", "pos": [ 75, 82 ], "name": "blocked" }
{ "id": "C1449702", "pos": [ 90, 115 ], "name": "protein kinase inhibitors" }
0NA
During and after cardiopulmonary bypass ( CPB ) RFR decreased with simultaneous loss of potassium and gain in sodium .
{ "id": "C0032821", "pos": [ 88, 97 ], "name": "potassium" }
{ "id": "C0007202", "pos": [ 17, 39 ], "name": "cardiopulmonary bypass" }
0NA
The coeliac disease is an immune-mediated enteropathy triggered by an ingestion of gluten in genetically susceptible individuals .
{ "id": "C2362561", "pos": [ 83, 89 ], "name": "gluten" }
{ "id": "C0007570", "pos": [ 4, 19 ], "name": "coeliac disease" }
4causative_agent_of
Cervical thymus was detected incidentally in the neck dissection resection specimen for thyroid medullary carcinoma extension .
{ "id": "C0015252", "pos": [ 65, 74 ], "name": "resection" }
{ "id": "C0398395", "pos": [ 49, 64 ], "name": "neck dissection" }
0NA
Raynaud 's phenomenon and mammary and axillary lymphadenopathy .
{ "id": "C0006141", "pos": [ 26, 33 ], "name": "mammary" }
{ "id": "C0578735", "pos": [ 38, 62 ], "name": "axillary lymphadenopathy" }
0NA
However , propranolol treatment increased the percent of glucose extracted by the liver without affecting the extractions of insulin or glucagon .
{ "id": "C0033497", "pos": [ 10, 21 ], "name": "propranolol" }
{ "id": "C0017725", "pos": [ 57, 64 ], "name": "glucose" }
0NA
Dendrophthoe falcata ( L.f ) Ettingsh ( Loranthaceae ) of the order Santalales , is used ethnomedicinally for treating ulcers , asthma , impotence , paralysis , skin diseases , and wounds .
{ "id": "C0041582", "pos": [ 119, 125 ], "name": "ulcers" }
{ "id": "C0037274", "pos": [ 161, 174 ], "name": "skin diseases" }
0NA
It is concluded that flunarizine is an effective drug for the treatment of childhood migraine .
{ "id": "C0013227", "pos": [ 49, 53 ], "name": "drug" }
{ "id": "C0016295", "pos": [ 21, 32 ], "name": "flunarizine" }
0NA
The in vitro and in situ rat ileal permeabilities of the LNAA carrier-mediated compounds neurontin , pregabalin , and phenylalanine correlated well with the corresponding in vivo human oral absorption .
{ "id": "C0657912", "pos": [ 101, 111 ], "name": "pregabalin" }
{ "id": "C0031453", "pos": [ 118, 131 ], "name": "phenylalanine" }
0NA
The maximum benefit was found in the lower legs , where the small arterial vessel diameters and propensity for leg movement during image acquisitions posed considerable problems in making accurate diagnoses from the un-registered images .
{ "id": "C0023216", "pos": [ 111, 114 ], "name": "leg" }
{ "id": "C0026649", "pos": [ 115, 123 ], "name": "movement" }
0NA
The literature on structural brain abnormalities in schizophrenia is examined to determine whether these abnormalities represent viable candidate markers of vulnerability to the disorder .
{ "id": "C0000768", "pos": [ 105, 118 ], "name": "abnormalities" }
{ "id": "C0036341", "pos": [ 52, 65 ], "name": "schizophrenia" }
0NA
Left ventricular ( LV ) ejection fraction ( EF ) , end-diastolic volume ( EDV ) , end-systolic volume ( ESV ) , stroke volume ( SV ) , mass ( M ) , and mass-to-volume ratio ( MVR ) were measured in a sample of 4,654 participants of the UK Biobank Study 6.3 ± 1 years after baseline using cardiovascular magnetic resonance ( CMR ) .
{ "id": "C0577559", "pos": [ 135, 139 ], "name": "mass" }
{ "id": "C0038454", "pos": [ 112, 118 ], "name": "stroke" }
0NA
Therefore , we hypothesized that in vivo peripheral nerve targets can be imaged using MCMRI with specific MRI probes .
{ "id": "C0024485", "pos": [ 106, 109 ], "name": "MRI" }
{ "id": "C0031119", "pos": [ 41, 57 ], "name": "peripheral nerve" }
0NA
Prostate cancer is the most common cancer affecting males in developed countries .
{ "id": "C0006826", "pos": [ 35, 41 ], "name": "cancer" }
{ "id": "C0376358", "pos": [ 0, 15 ], "name": "Prostate cancer" }
0NA
It is concluded that the duodenal lactic acid concentration may have a role in the control of food intake by a mechanism involving central opiate mediation .
{ "id": "C0013303", "pos": [ 25, 33 ], "name": "duodenal" }
{ "id": "C0013470", "pos": [ 94, 105 ], "name": "food intake" }
0NA
None of the eyes developed endophthalmitis .
{ "id": "C0015392", "pos": [ 12, 16 ], "name": "eyes" }
{ "id": "C0014236", "pos": [ 27, 42 ], "name": "endophthalmitis" }
11finding_site_of
Patients were randomized to RT alone or RT preceded by chemotherapy with vincristine , etoposide , carboplatin , and cyclophosphamide .
{ "id": "C0013216", "pos": [ 55, 67 ], "name": "chemotherapy" }
{ "id": "C0015133", "pos": [ 87, 96 ], "name": "etoposide" }
0NA
Terms searched included combinations of Pneumocystis jirovecii , Pneumocystis carinii , non-HIV , infected , patients , prevention , prophylaxis , Bactrim , treatment , AIDS , opportunistic , immunocompromised , cancer , and pathophysiology
{ "id": "C0199176", "pos": [ 120, 130 ], "name": "prevention" }
{ "id": "C0001175", "pos": [ 169, 173 ], "name": "AIDS" }
0NA
Trophozoites and cysts were found within the perivascular space .
{ "id": "C0010709", "pos": [ 17, 22 ], "name": "cysts" }
{ "id": "C0225983", "pos": [ 45, 63 ], "name": "perivascular space" }
0NA
This cross sectional study assessed the prevalence of risk factors and occurrence of oral precancerous lesions in a low income group expatriate community from the Indian subcontinent residing in Qatar .
{ "id": "C0221198", "pos": [ 103, 110 ], "name": "lesions" }
{ "id": "C0226896", "pos": [ 85, 89 ], "name": "oral" }
0NA
While the mechanism of this pulmonary toxicity is unknown , it may be associated with the accumulation of amiodarone and its principal metabolite , desethylamiodarone , by alveolar macrophages .
{ "id": "C0057522", "pos": [ 148, 166 ], "name": "desethylamiodarone" }
{ "id": "C0002598", "pos": [ 106, 116 ], "name": "amiodarone" }
16is_modification_of
To investigate the association between Helicobacter pylori infection and its inflammatory reaction in gastritis , gastric ulcer , and gastric cancer , a new tumor necrosis factor-alpha (TNF-alpha)-inducing protein of H. pylori was studied .
{ "id": "C0021368", "pos": [ 77, 98 ], "name": "inflammatory reaction" }
{ "id": "C0017152", "pos": [ 102, 111 ], "name": "gastritis" }
3associated_morphology_of
These malignant tumors occur more frequently in women , and their symptomatology varies according to their location in either the upper , middle or lower area of the inferior vena cava .
{ "id": "C0006826", "pos": [ 6, 22 ], "name": "malignant tumors" }
{ "id": "C0042458", "pos": [ 166, 184 ], "name": "inferior vena cava" }
0NA
The results suggest that decreased distal delivery of sodium may underlie the abnormality in the concentrating mechanism and in the inability to normally excrete a water load .
{ "id": "C0037473", "pos": [ 54, 60 ], "name": "sodium" }
{ "id": "C0011209", "pos": [ 42, 50 ], "name": "delivery" }
0NA
In a restraint-induced oxidative stress model in mice , quercetin significantly attenuated the increase in plasma ALT and AST levels as well as liver MDA content of restrained mice .
{ "id": "C0023884", "pos": [ 144, 149 ], "name": "liver" }
{ "id": "C0032105", "pos": [ 107, 113 ], "name": "plasma" }
0NA
In networks with spike-timing-dependent plasticity CR stimulation may ultimately cause an anti-kindling , i.e. , an unlearning of abnormal synaptic connectivity and neuronal synchrony .
{ "id": "C0205161", "pos": [ 130, 138 ], "name": "abnormal" }
{ "id": "C1292856", "pos": [ 54, 65 ], "name": "stimulation" }
0NA
Raman spectroscopy , associated with the PLS , is promising as a serological assay for toxoplasmosis , enabling fast and sensitive diagnosis .
{ "id": "C0020517", "pos": [ 121, 130 ], "name": "sensitive" }
{ "id": "C0030360", "pos": [ 41, 44 ], "name": "PLS" }
0NA
ANP , BNP and norepinephrine/epinephrine ( NE/E ) were determined at baseline and at 80 % .VO2 max workload and after recovery , before and following 12 weeks of treatment with fosinopril ( 10 mg/d ) .
{ "id": "C0118168", "pos": [ 177, 187 ], "name": "fosinopril" }
{ "id": "C0054015", "pos": [ 6, 9 ], "name": "BNP" }
0NA
Traditional therapy of patients with new and chronic gonorrhea complicated with prostatitis has augmented testicular androgenic insufficiency , hyperprolactin- and hyperprogesteronemia , and estrogen share in the hormonal profile ; inclusion into the complex of therapeutic measures of sustanon-250 , a long-acting androgen , and of raveron have not corrected the hormonal ratio .
{ "id": "C0014939", "pos": [ 191, 199 ], "name": "estrogen" }
{ "id": "C0275655", "pos": [ 45, 62 ], "name": "chronic gonorrhea" }
0NA
The right knee joint of male adolescent Japanese white rabbits was entered through a medial parapatellan approach , and the patella was dislocated laterally to expose the articular surface of the femoral trochlea .
{ "id": "C0022417", "pos": [ 171, 180 ], "name": "articular" }
{ "id": "C0012691", "pos": [ 136, 146 ], "name": "dislocated" }
11finding_site_of
This study aimed to assess the safety and efficacy of iron sucrose in hemodialysis ( HD ) patients with documented hypersensitivity reactions to iron dextran .
{ "id": "C0060241", "pos": [ 54, 66 ], "name": "iron sucrose" }
{ "id": "C0019004", "pos": [ 70, 82 ], "name": "hemodialysis" }
0NA
Voltage dependent sodium channels are widely recognized as valuable targets for the development of therapeutic interventions for neuroexcitatory disorders such as epilepsy and pain as well as cardiac arrhythmias .
{ "id": "C0003811", "pos": [ 192, 211 ], "name": "cardiac arrhythmias" }
{ "id": "C0014544", "pos": [ 163, 171 ], "name": "epilepsy" }
0NA
RPGN without immune complexes was present in four , immune complex disease in four , and anti-glomerular basement membrane disease in two .
{ "id": "C0003313", "pos": [ 13, 29 ], "name": "immune complexes" }
{ "id": "C0403529", "pos": [ 89, 130 ], "name": "anti-glomerular basement membrane disease" }
4causative_agent_of
Control samples were obtained from the normal testis of two patients with testicular cancer who underwent orchidectomy .
{ "id": "C0039597", "pos": [ 46, 52 ], "name": "testis" }
{ "id": "C0153594", "pos": [ 74, 91 ], "name": "testicular cancer" }
11finding_site_of
The size , shape and time of onset suggested that the thrombus had been formed by residual blood left after administration of protamine .
{ "id": "C0087086", "pos": [ 54, 62 ], "name": "thrombus" }
{ "id": "C0033603", "pos": [ 126, 135 ], "name": "protamine" }
0NA
The probe can selectively detect Pb(2 + ) ions in live cells and living tissues without interference from other metal ions and the membrane-bound probes , and its quenching constant ( K(SV)(TP ) ) is 7.58 × 10(5 ) M(-1 ) .
{ "id": "C0442726", "pos": [ 26, 32 ], "name": "detect" }
{ "id": "C0182400", "pos": [ 4, 9 ], "name": "probe" }
0NA
Even if significant intraoperative blood loss occurs , successful postoperative management is possible by utilizing techniques that minimize oxygen consumption and maximize oxygen delivery .
{ "id": "C0019080", "pos": [ 35, 45 ], "name": "blood loss" }
{ "id": "C0429622", "pos": [ 173, 188 ], "name": "oxygen delivery" }
0NA
In the proposed procedure , following the span measurement , two subsequent exponential dilution experiments are completed in which the responses of the electrode for the primary and the interfering ions are tested using a solution of a discriminated ion and deionized water as diluting electrolytes in consecution .
{ "id": "C0013832", "pos": [ 287, 299 ], "name": "electrolytes" }
{ "id": "C0184661", "pos": [ 16, 25 ], "name": "procedure" }
0NA
Time to stone expulsion , number of colic episodes , analgesic use , number of hospital visits for pain , endoscopic treatment , and adverse effects of the drugs were noted .
{ "id": "C0013227", "pos": [ 156, 161 ], "name": "drugs" }
{ "id": "C0232488", "pos": [ 36, 41 ], "name": "colic" }
0NA
We present a 71-year-old man with primary amyloidosis characterized by several outstanding clinical features , namely hip involvement of a pseudotumoral appearance , periarticular osteolytic lesions and a pathological fracture .
{ "id": "C0019552", "pos": [ 118, 121 ], "name": "hip" }
{ "id": "C0268381", "pos": [ 34, 53 ], "name": "primary amyloidosis" }
0NA
Based on preoperative imaging , each mass was designated as central ( touching or encroaching upon the renal collecting system and/or renal sinus ) or peripheral .
{ "id": "C0577559", "pos": [ 37, 41 ], "name": "mass" }
{ "id": "C0011923", "pos": [ 22, 29 ], "name": "imaging" }
0NA
One participant succumbed following the procedure due to unrelated diseases .
{ "id": "C0184661", "pos": [ 40, 49 ], "name": "procedure" }
{ "id": "C0012634", "pos": [ 67, 75 ], "name": "diseases" }
0NA
Donor immunization enhances early antibody responses of patients undergoing HCT to pneumococcal conjugate vaccine .
{ "id": "C0020971", "pos": [ 6, 18 ], "name": "immunization" }
{ "id": "C0042210", "pos": [ 106, 113 ], "name": "vaccine" }
0NA
Our data suggest that the decrease in DHEA and DHEA-S in remitters is related to remission of depression rather than to a direct drug effect on steroids , as nonremitters had no change in hormone concentrations .
{ "id": "C0038317", "pos": [ 144, 152 ], "name": "steroids" }
{ "id": "C0011185", "pos": [ 38, 42 ], "name": "DHEA" }
0NA
In the 16th week of treatment , the patient experienced headache and fever and developed a markedly decreased , platelet count and hemolytic anemia .
{ "id": "C0002878", "pos": [ 131, 147 ], "name": "hemolytic anemia" }
{ "id": "C0032181", "pos": [ 112, 126 ], "name": "platelet count" }
0NA