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Right ventricular ejection fractions ranged from 7 - 54 % , mean 30 + /- 11 % , which was significantly lower than values obtained from normal volunteers ( n = 21 ) , mean 43 + /- 5 % , and patients with arteriographically proven coronary artery disease without previous myocardial infarction ( n = 12 ) , mean 39 + /- 9 % , P less than 0.001 , and P less than 0.001 , respectively .
{ "id": "C0027051", "pos": [ 271, 292 ], "name": "myocardial infarction" }
{ "id": "C0010054", "pos": [ 230, 253 ], "name": "coronary artery disease" }
0NA
Progressive substitution took place at the interface of implants and host bones .
{ "id": "C0262950", "pos": [ 74, 79 ], "name": "bones" }
{ "id": "C0021102", "pos": [ 56, 64 ], "name": "implants" }
0NA
Finally , anti-transglutaminase ( tTG ) IgG1 antibodies were detected in sera of infected animal belonging to both groups , as already described for human inflammatory bowel diseases .
{ "id": "C0229671", "pos": [ 73, 77 ], "name": "sera" }
{ "id": "C0021390", "pos": [ 155, 182 ], "name": "inflammatory bowel diseases" }
0NA
The urinary bladder did not have evidence of macroscopic leakage or microscopic alterations of normal tissue architecture within the representative sections chosen for histologic examination .
{ "id": "C0005682", "pos": [ 4, 19 ], "name": "urinary bladder" }
{ "id": "C0040300", "pos": [ 102, 108 ], "name": "tissue" }
0NA
We prospectively included patients receiving serial MRI examinations between 4.5 and 35 hours from symptom onset .
{ "id": "C0024485", "pos": [ 52, 55 ], "name": "MRI" }
{ "id": "C0031809", "pos": [ 56, 68 ], "name": "examinations" }
0NA
Cox proportional hazard regression analysis was used to calculate the overall hazard of hemodialysis initiation in regard to incident cataract surgery after adjusting for the above factors , hypertension , and diabetes mellitus .
{ "id": "C0011849", "pos": [ 210, 227 ], "name": "diabetes mellitus" }
{ "id": "C0020538", "pos": [ 191, 203 ], "name": "hypertension" }
0NA
Clinical evaluation is of limited value in the assessment of patients with traumatic brain injury and is often inaccurate in determining the extent of brain damage .
{ "id": "C1261322", "pos": [ 0, 19 ], "name": "Clinical evaluation" }
{ "id": "C0031809", "pos": [ 47, 57 ], "name": "assessment" }
17method_of
Knowledge of aortic shape and size is very important for selection of appropriate stent graft device for treatment of AAA .
{ "id": "C0003483", "pos": [ 13, 19 ], "name": "aortic" }
{ "id": "C0003486", "pos": [ 118, 121 ], "name": "AAA" }
11finding_site_of
These neoplastic markers showed substantial alteration leading to slow development of tumors and increased survival of the host bearing lymphocytic leukemia .
{ "id": "C0027651", "pos": [ 86, 92 ], "name": "tumors" }
{ "id": "C0023448", "pos": [ 136, 156 ], "name": "lymphocytic leukemia" }
0NA
In a second study , lateral wall motion was assessed in 20 cleft palate patients with repaired hard and soft palate but with velopharyngeal inadequacy .
{ "id": "C0030219", "pos": [ 104, 115 ], "name": "soft palate" }
{ "id": "C0008925", "pos": [ 59, 71 ], "name": "cleft palate" }
0NA
Serum tryptase ( Tryp ) and eosinophil cationic protein ( ECP ) and urine N-methylhistamine ( N-MH ) were quantitated in a group of 13 subjects who had experienced immediate allergic reactions to different drugs .
{ "id": "C0013227", "pos": [ 206, 211 ], "name": "drugs" }
{ "id": "C0020517", "pos": [ 174, 192 ], "name": "allergic reactions" }
0NA
Pulmonary sequestration is an uncommon congenital malformation of the lung that can be classified as intralobar or extralobar ( ELS ) .
{ "id": "C0024109", "pos": [ 70, 74 ], "name": "lung" }
{ "id": "C0006288", "pos": [ 0, 23 ], "name": "Pulmonary sequestration" }
11finding_site_of
The pathogenesis of tuberculosis involves multiple phases and is believed to involve both a carefully deployed series of adaptive bacterial virulence factors and inappropriate host immune responses that lead to tissue damage .
{ "id": "C0010957", "pos": [ 211, 224 ], "name": "tissue damage" }
{ "id": "C0301872", "pos": [ 181, 197 ], "name": "immune responses" }
0NA
To study protective effects of vigabatrin ( 600 mg/kg , i.p . ) , drug was injected either 24 h before or immediately after hypoxia exposure .
{ "id": "C0013227", "pos": [ 66, 70 ], "name": "drug" }
{ "id": "C0274281", "pos": [ 132, 140 ], "name": "exposure" }
0NA
The clinical outcome was evaluated by the Harvey-Bradshaw index or the closure of ano-perineal fistulas .
{ "id": "C0185003", "pos": [ 71, 78 ], "name": "closure" }
{ "id": "C0016169", "pos": [ 95, 103 ], "name": "fistulas" }
0NA
This suggests that the renin-angiotensin system may play an important role in the initial responses to hypotension in anurans , whether brought about by haemorrhage or dehydration .
{ "id": "C0019080", "pos": [ 153, 164 ], "name": "haemorrhage" }
{ "id": "C0020649", "pos": [ 103, 114 ], "name": "hypotension" }
0NA
PAI-1 overexpression in retinal microvasculature leads to retinal disease similar to that observed in diabetic retinopathy .
{ "id": "C0035298", "pos": [ 24, 31 ], "name": "retinal" }
{ "id": "C0035309", "pos": [ 58, 73 ], "name": "retinal disease" }
11finding_site_of
Brains were frozen in situ at the end of ischemia and after 1 , 2 , and 4 hr of recirculation .
{ "id": "C0006104", "pos": [ 0, 6 ], "name": "Brains" }
{ "id": "C0022116", "pos": [ 41, 49 ], "name": "ischemia" }
0NA
The authors presented current views on usefulness of computed tomography ( CT ) for diagnosing the bleeding from a ruptured intracranial aneurysm .
{ "id": "C0019080", "pos": [ 99, 107 ], "name": "bleeding" }
{ "id": "C0040405", "pos": [ 53, 72 ], "name": "computed tomography" }
0NA
Peripheral arterial disease ( PAD ) is a group of syndromes characterized by chronic and progressive atherosclerosis with a high burden of physical disability and cardiovascular morbidity and mortality .
{ "id": "C0007226", "pos": [ 163, 177 ], "name": "cardiovascular" }
{ "id": "C0085096", "pos": [ 0, 27 ], "name": "Peripheral arterial disease" }
0NA
Bone marrow ( BM ) examination is included in the diagnostic algorithm of fever of unknown origin ( FUO ) , although its role is not clearly determined .
{ "id": "C0031809", "pos": [ 19, 30 ], "name": "examination" }
{ "id": "C0005953", "pos": [ 0, 11 ], "name": "Bone marrow" }
0NA
After euthanasia , sciatic nerves were removed at the end of reperfusion times and sections were cut at 5 μm , then were stained for light microscopy studies and graded for ischemic fiber degeneration ( IFD ) , edema , and apoptosis .
{ "id": "C0013604", "pos": [ 211, 216 ], "name": "edema" }
{ "id": "C0036394", "pos": [ 19, 33 ], "name": "sciatic nerves" }
0NA
In addiction , notably Alcohol Use Disorder ( AUD ) , patients often have a tendency to fail to acknowledge the reality of the disease and to minimize the physical , psychological , and social difficulties attendant to chronic alcohol consumption .
{ "id": "C0031809", "pos": [ 155, 163 ], "name": "physical" }
{ "id": "C0012634", "pos": [ 127, 134 ], "name": "disease" }
0NA
Since the N-terminus of the major proteins was blocked , peptides were generated with trypsin and endoproteinase Asp-N and then isolated using reversed-phase high-performance liquid chromatography .
{ "id": "C0028778", "pos": [ 47, 54 ], "name": "blocked" }
{ "id": "C0030956", "pos": [ 57, 65 ], "name": "peptides" }
0NA
For all patients , HD had been diagnosed by rectal biopsy or excluded by biopsy , clinical follow-up , or both .
{ "id": "C0005558", "pos": [ 73, 79 ], "name": "biopsy" }
{ "id": "C0193050", "pos": [ 44, 57 ], "name": "rectal biopsy" }
17method_of
The purpose of this study was to demonstrate the unusual MR imaging patterns of vertebral osteomyelitis with intraosseous lesions mimicking metastases .
{ "id": "C0024485", "pos": [ 57, 67 ], "name": "MR imaging" }
{ "id": "C0452221", "pos": [ 80, 103 ], "name": "vertebral osteomyelitis" }
0NA
Participants in the exposure plus distraction condition also reported the greatest reduction in fear between sessions , at post-treatment , and at 1-month follow-up .
{ "id": "C0012634", "pos": [ 46, 55 ], "name": "condition" }
{ "id": "C0150189", "pos": [ 34, 45 ], "name": "distraction" }
0NA
Ciprofloxacin was found to be the most effective drug against aerobes and metronidazole against anaerobes in vitro susceptibility tests .
{ "id": "C0008809", "pos": [ 0, 13 ], "name": "Ciprofloxacin" }
{ "id": "C0013227", "pos": [ 49, 53 ], "name": "drug" }
0NA
A splenectomy is the treatment of choice in cases of splenic torsion and infarction , while in patients with chronic symptoms splenopexy may also be attempted .
{ "id": "C0021308", "pos": [ 73, 83 ], "name": "infarction" }
{ "id": "C0194025", "pos": [ 126, 136 ], "name": "splenopexy" }
0NA
In any ADS occurring in the context of SCD and/or autoimmune condition , we recommend to slowly wean steroids and to closely monitor the patient after weaning to quickly treat any recurrence of neurological symptom with IVMP .
{ "id": "C0038317", "pos": [ 101, 109 ], "name": "steroids" }
{ "id": "C0004364", "pos": [ 50, 70 ], "name": "autoimmune condition" }
0NA
To explore the feasibility of using a new magnetic resonance imaging ( MRI ) technique -- magnetic resonance elastography (MRE)--to identify and quantitate the nature of myofascial taut bands .
{ "id": "C0024485", "pos": [ 42, 68 ], "name": "magnetic resonance imaging" }
{ "id": "C1518156", "pos": [ 90, 121 ], "name": "magnetic resonance elastography" }
17method_of
Key enzymes of energetic utilization of carbohydrates such as fructose-1.6-biphosphatase and glucose-6-phosphate dehydrogenase were reduced in their activities in livers and kidneys of Zn-deficient animals .
{ "id": "C0022646", "pos": [ 174, 181 ], "name": "kidneys" }
{ "id": "C0023884", "pos": [ 163, 169 ], "name": "livers" }
0NA
The option of including an atrium in the circuit , or the technique used for connecting the caval veins to the pulmonary artery in a total cavopulmonary connection , frequently is empirical and is based on personal experience and preference .
{ "id": "C0018792", "pos": [ 27, 33 ], "name": "atrium" }
{ "id": "C0034052", "pos": [ 111, 127 ], "name": "pulmonary artery" }
0NA
Enteroclysis patterns encountered in four patients with adult intestinal intussusception of different etiology -- including a leiomyoma , a Peutz-Jeghers hamartoma , a metastatic colon carcinoma , and adhesions -- were analyzed and compared to surgical and pathological findings .
{ "id": "C0021853", "pos": [ 62, 72 ], "name": "intestinal" }
{ "id": "C0021933", "pos": [ 73, 88 ], "name": "intussusception" }
11finding_site_of
Clinical , anthropometric , lung function , radiological , and analytical variables ( albumin , prealbumin , vitamins , and zinc ) were also recorded .
{ "id": "C0043481", "pos": [ 124, 128 ], "name": "zinc" }
{ "id": "C0001924", "pos": [ 86, 93 ], "name": "albumin" }
0NA
Both pili and outer membrane protein II occur in several different molecular forms among gonococci of a given strain , and expression of a particular form of each changes at high frequency in vitro .
{ "id": "C0018494", "pos": [ 5, 9 ], "name": "pili" }
{ "id": "C0080194", "pos": [ 110, 116 ], "name": "strain" }
0NA
Anxiety was assessed during separation from parents and induction of anesthesia by a modified Yale Preoperative Anxiety Scale .
{ "id": "C0036679", "pos": [ 28, 38 ], "name": "separation" }
{ "id": "C0002903", "pos": [ 69, 79 ], "name": "anesthesia" }
0NA
Seven elements , including copper ( Cu ) , zinc ( Zn ) , calcium ( Ca ) , magnesium ( Mg ) , iron ( Fe ) , lead ( Pb ) , and cadmium ( Cd ) , were analyzed on BOHUI 5100 and 2100 analyzers using blood samples from 4044 healthy infants and children .
{ "id": "C0024467", "pos": [ 74, 83 ], "name": "magnesium" }
{ "id": "C0006675", "pos": [ 57, 64 ], "name": "calcium" }
0NA
Sweeteners are often used to encourage consumption of agents such as ethanol and nicotine in laboratory studies using rodents .
{ "id": "C0028040", "pos": [ 81, 89 ], "name": "nicotine" }
{ "id": "C0001962", "pos": [ 69, 76 ], "name": "ethanol" }
0NA
The authors identified 67 eyes of 67 patients ( 33 males ) primarily enucleated for retinoblastoma between March 1997 and January 2008 .
{ "id": "C0015392", "pos": [ 26, 30 ], "name": "eyes" }
{ "id": "C0086582", "pos": [ 51, 56 ], "name": "males" }
0NA
The series of encounters reviewed included 215 unique patients with DBS implantation who were identified using an IRB approved database and a paper chart review .
{ "id": "C0394162", "pos": [ 68, 71 ], "name": "DBS" }
{ "id": "C0021107", "pos": [ 72, 84 ], "name": "implantation" }
0NA
We performed a retrospective study of 312 consecutive patients , diagnosed for MTC localized on face and scalp .
{ "id": "C0015450", "pos": [ 96, 100 ], "name": "face" }
{ "id": "C0036270", "pos": [ 105, 110 ], "name": "scalp" }
0NA
Retrospective review of clinical records and computed tomographic ( CT ) scans of 557 patients who underwent thyroid surgery at the Departments of Otolaryngology , Head and Neck Surgery of Manukau Surgery Center and Whangarei Base Hospital .
{ "id": "C0018670", "pos": [ 164, 168 ], "name": "Head" }
{ "id": "C0193769", "pos": [ 109, 124 ], "name": "thyroid surgery" }
0NA
The increase of the pyruvic acid o blood caused for the higher level of sulfite ( 50 mg/kg/day ) is considerably increased for absorption of a diet containing 67 % of sugar , and considerably decreased by injection the day before the dosage of 200 microgram thiamine .
{ "id": "C0005767", "pos": [ 35, 40 ], "name": "blood" }
{ "id": "C0021485", "pos": [ 205, 214 ], "name": "injection" }
0NA
Carcinomas with and without atrophic features did not differ in histologic grade , tumor volume , or pathologic stage .
{ "id": "C0007097", "pos": [ 0, 10 ], "name": "Carcinomas" }
{ "id": "C0151514", "pos": [ 28, 36 ], "name": "atrophic" }
0NA
Usually , single TMS pulses are targeted to the motor cortex with the help of neuronavigation and by measuring motor evoked potential ( MEP ) amplitudes from the peripheral muscles .
{ "id": "C0436548", "pos": [ 17, 20 ], "name": "TMS" }
{ "id": "C0034107", "pos": [ 21, 27 ], "name": "pulses" }
0NA
The effect of temperature on the SNR and the sensitivity of the sensor with two different metals has been compared .
{ "id": "C0020517", "pos": [ 45, 56 ], "name": "sensitivity" }
{ "id": "C0005903", "pos": [ 14, 25 ], "name": "temperature" }
0NA
Because animal studies suggest that postjunctional alpha(2)-adrenoreceptors are located mainly on venous capacitance rather than arterial resistance vessels , we tested the hypothesis that venoconstriction is the main mechanism by which clonidine raises blood pressure in patients with autonomic failure .
{ "id": "C0009014", "pos": [ 237, 246 ], "name": "clonidine" }
{ "id": "C0005823", "pos": [ 254, 268 ], "name": "blood pressure" }
0NA
This bile acid occurs naturally in human feces but induces cirrhosis of the liver when fed to a wide variety of experimental animals .
{ "id": "C0023884", "pos": [ 76, 81 ], "name": "liver" }
{ "id": "C0023890", "pos": [ 59, 68 ], "name": "cirrhosis" }
11finding_site_of
As predicted , negative staining for p40 and p63 was observed in testis and intestine .
{ "id": "C0021853", "pos": [ 76, 85 ], "name": "intestine" }
{ "id": "C0039597", "pos": [ 65, 71 ], "name": "testis" }
0NA
The efficacy of simultaneous antegrade-retrograde cardioplegia for myocardial perfusion was assessed by monitoring the distribution of magnetic resonance contrast agent and measuring the effluent from the venting coronary arteries .
{ "id": "C0205042", "pos": [ 213, 230 ], "name": "coronary arteries" }
{ "id": "C0150369", "pos": [ 104, 114 ], "name": "monitoring" }
0NA
All were isolated from respiratory tract ( diseases 5 , healthy carriage 1 ) .
{ "id": "C0035237", "pos": [ 23, 40 ], "name": "respiratory tract" }
{ "id": "C0012634", "pos": [ 43, 51 ], "name": "diseases" }
0NA
Comparing the data of the two groups , we observed that surgical patients showed higher exercise tolerance ( P < .01 ) , lower S-T depression ( P < .001 ) and angina incidence .
{ "id": "C0002962", "pos": [ 159, 165 ], "name": "angina" }
{ "id": "C0543467", "pos": [ 56, 64 ], "name": "surgical" }
0NA
In a prospective cohort study in 4118 patients who underwent cardiac and thoracic aortic surgery , the effect of changes in serum creatinine within 48 h postoperatively on 30-d mortality was analyzed .
{ "id": "C0018787", "pos": [ 61, 68 ], "name": "cardiac" }
{ "id": "C0201976", "pos": [ 124, 140 ], "name": "serum creatinine" }
0NA
They give an account of eight cases of the disease in 647 patients where during the last 22 years transplantations where performed in the Institute for Clinical and Experimental Medicine .
{ "id": "C0040732", "pos": [ 98, 114 ], "name": "transplantations" }
{ "id": "C0012634", "pos": [ 43, 50 ], "name": "disease" }
0NA
Outcome studies have shown methoxamine to be comparable to epinephrine in resuscitation from asphyxial arrest .
{ "id": "C0014563", "pos": [ 59, 70 ], "name": "epinephrine" }
{ "id": "C0025681", "pos": [ 27, 38 ], "name": "methoxamine" }
0NA
To understand the function , it is necessary to know how the stress and strain in the esophagus can be computed , and how to determine the stress-strain relationship of the wall materials .
{ "id": "C0014876", "pos": [ 86, 95 ], "name": "esophagus" }
{ "id": "C0080194", "pos": [ 72, 78 ], "name": "strain" }
0NA
We have studied human thyroglobulin of extremely low iodine content obtained from a goitrous cretin who had no measurable peroxidase activity in his thyroid gland .
{ "id": "C0040132", "pos": [ 149, 162 ], "name": "thyroid gland" }
{ "id": "C0342149", "pos": [ 84, 99 ], "name": "goitrous cretin" }
11finding_site_of
In a previous study , we demonstrated that rAAV-mediated gene transfer of the tetracycline-regulatable ( tetR ) system allows transgene regulation in the retina of nonhuman primates after intravenous administration of doxycycline ( Dox ) .
{ "id": "C0013090", "pos": [ 218, 229 ], "name": "doxycycline" }
{ "id": "C0013089", "pos": [ 232, 235 ], "name": "Dox" }
0NA
We investigated the status of estrogen receptor alpha ( ERα ) , progesterone receptor ( PR ) , and epidermal growth factor receptor 2 ( HER2 ) in primary tumor and in the corresponding brain metastases in a consecutive series of breast cancer patients .
{ "id": "C0006142", "pos": [ 229, 242 ], "name": "breast cancer" }
{ "id": "C0220650", "pos": [ 185, 201 ], "name": "brain metastases" }
0NA
The basic strategy for construction of the FFA-producing mutant was a commonly used one , involving inactivation of the endogenous acyl-acyl carrier protein synthetase gene ( aas ) and introduction of a foreign thioesterase gene ( ' tesA ) , but a nitrate transport mutant NA3 was used as the parental strain to achieve slow , nitrate-limited growth in batch cultures .
{ "id": "C0441513", "pos": [ 23, 35 ], "name": "construction" }
{ "id": "C0080194", "pos": [ 302, 308 ], "name": "strain" }
0NA
Magnetization measurements indicate that nanospheres are superparamagnetic above the blocking temperature T(B ) = 300 K , which is associated with the higher magnetocrystalline anisotropy constant K = 3.33 kJ m(-3 ) .
{ "id": "C0233660", "pos": [ 85, 93 ], "name": "blocking" }
{ "id": "C0005903", "pos": [ 94, 105 ], "name": "temperature" }
0NA
Adjunctive therapy with corticosteroids improves the outcome in patients with AIDS and severe PCP .
{ "id": "C0205082", "pos": [ 87, 93 ], "name": "severe" }
{ "id": "C0001617", "pos": [ 24, 39 ], "name": "corticosteroids" }
0NA
The excisional biopsy of the conjunctiva revealed a dysplasic epithelial tissue that allowed the diagnosis of papilloma with parts of conjunctival intraepithelial neoplasia ( CIN ) .
{ "id": "C0009758", "pos": [ 29, 40 ], "name": "conjunctiva" }
{ "id": "C1333148", "pos": [ 134, 172 ], "name": "conjunctival intraepithelial neoplasia" }
11finding_site_of
Of the 796 patients assessed for UGI bleeding , 727 ( 91 % ) had upper endoscopy .
{ "id": "C0019080", "pos": [ 37, 45 ], "name": "bleeding" }
{ "id": "C0017195", "pos": [ 65, 80 ], "name": "upper endoscopy" }
0NA
Interaction of sodium hypochlorite ( NaOCl ) mixed with chlorhexidine ( CHX ) produces a brown precipitate containing para-chloroaniline ( PCA ) .
{ "id": "C0008196", "pos": [ 56, 69 ], "name": "chlorhexidine" }
{ "id": "C0037420", "pos": [ 0, 11 ], "name": "Interaction" }
0NA
The FCSEMS arm had the stent in situ for 12 weeks with the plastic stent arm undergoing 3-monthly multiple plastic stenting with or without dilatation over a year .
{ "id": "C0002940", "pos": [ 140, 150 ], "name": "dilatation" }
{ "id": "C0038257", "pos": [ 23, 28 ], "name": "stent" }
0NA
In this paper it is suggested that this pathological state could be considered as a metabolic marker that could predict occurrence of diseases in adulthood , such as cardiovascular disease , obesity , diabetes mellitus ( including gestational diabetes ) , and metabolic syndrome .
{ "id": "C0011849", "pos": [ 201, 218 ], "name": "diabetes mellitus" }
{ "id": "C0012634", "pos": [ 134, 142 ], "name": "diseases" }
0NA
BMD ( mean + /- SD ) , measured using dual-energy X-ray absorptiometry , decreased by a maximum of 35 + /- 21 % in the mid-diaphysis of the affected tibia at 9 months after surgery ( p < 0.001 ) .
{ "id": "C1510486", "pos": [ 38, 70 ], "name": "dual-energy X-ray absorptiometry" }
{ "id": "C0040184", "pos": [ 149, 154 ], "name": "tibia" }
0NA
Pedicle , vertebral , and critical breach rates for the L1-S1 were 32.1 % , 10.7 % , and 25.0 % for conventional fluoroscopy and 42.8 % , 10.7 % , and 14.1 % for electromagnetic guidance ( difference not statistically significant [ ns ] ) .
{ "id": "C0016356", "pos": [ 113, 124 ], "name": "fluoroscopy" }
{ "id": "C0549207", "pos": [ 10, 19 ], "name": "vertebral" }
0NA
Timely presentation to the referral centre and proper multidisciplinary approach towards management plays a pivotal role in the healing pattern of the wound and prevention of serious complication like shock , sepsis , laryngeal stenosis or fistula formation .
{ "id": "C0043250", "pos": [ 151, 156 ], "name": "wound" }
{ "id": "C0043240", "pos": [ 128, 135 ], "name": "healing" }
3associated_morphology_of
The irradiation of the whole brain remains the most commonly undertaken treatment , but should be discussed in relation to other therapeutic alternatives such as stereotactic radiotherapy or the use of new chemotherapy drugs .
{ "id": "C0013227", "pos": [ 219, 224 ], "name": "drugs" }
{ "id": "C0013216", "pos": [ 206, 218 ], "name": "chemotherapy" }
10direct_substance_of
Our study demonstrates the feasibility of isolation of ECs from histologically normal prostate and prostate cancer via CD31 + selection .
{ "id": "C0033572", "pos": [ 86, 94 ], "name": "prostate" }
{ "id": "C0376358", "pos": [ 99, 114 ], "name": "prostate cancer" }
11finding_site_of
Repeated proton beam therapy for HCC is safe when the patient has a target in the peripheral region of the liver and liver function is Child-Pugh class A.
{ "id": "C0023884", "pos": [ 107, 112 ], "name": "liver" }
{ "id": "C0232741", "pos": [ 117, 131 ], "name": "liver function" }
0NA
In spite of significant efforts to enhance guidance for catheter navigation , limited research has been conducted to consider the changes that occur in the tissue during ablation as means to provide useful feedback on the progression of therapy delivery .
{ "id": "C0547070", "pos": [ 170, 178 ], "name": "ablation" }
{ "id": "C0040300", "pos": [ 156, 162 ], "name": "tissue" }
0NA
Statistically significant differences in TEWL were observed between the lumbar region and the left side of the thorax region ( P=0.016 ) , the axillary fossa ( P=0.0004 ) , the ventral region ( P=0.005 ) , and the inguinal region ( P=0.009 ) .
{ "id": "C0024090", "pos": [ 72, 85 ], "name": "lumbar region" }
{ "id": "C0018246", "pos": [ 214, 229 ], "name": "inguinal region" }
0NA
When the data was subjected to statistical analysis , it was observed that both drugs resulted in adequate sedation at the end of 30 min , with oral midazolam providing significantly better anxiolysis .
{ "id": "C0013227", "pos": [ 80, 85 ], "name": "drugs" }
{ "id": "C0026056", "pos": [ 149, 158 ], "name": "midazolam" }
0NA
This article describes a case of a 58-year-old man with no significant underlying disease who had chronic pain due to osteonecrosis of the hamate .
{ "id": "C0012634", "pos": [ 82, 89 ], "name": "disease" }
{ "id": "C0560737", "pos": [ 139, 145 ], "name": "hamate" }
0NA
Two qualified radiologists independently reviewed the studies and any previous available imaging and categorised any detected incidental findings .
{ "id": "C0442726", "pos": [ 117, 125 ], "name": "detected" }
{ "id": "C0011923", "pos": [ 89, 96 ], "name": "imaging" }
0NA
If delivery is imminent , maternal glucose response to betamethasone may need to be monitored to prevent possible neonatal hypoglycemia .
{ "id": "C0011209", "pos": [ 3, 11 ], "name": "delivery" }
{ "id": "C0020615", "pos": [ 123, 135 ], "name": "hypoglycemia" }
0NA
Resistance to CO was not detected , whereas 8 % of the strains were resistant to TIG .
{ "id": "C0305058", "pos": [ 81, 84 ], "name": "TIG" }
{ "id": "C0080194", "pos": [ 55, 62 ], "name": "strains" }
0NA
The catheter was flushed with heparinized saline to ensure patency .
{ "id": "C0085590", "pos": [ 4, 12 ], "name": "catheter" }
{ "id": "C0016382", "pos": [ 17, 24 ], "name": "flushed" }
0NA
Skeletal muscle atrophy is a debilitating response to starvation and many systemic diseases including diabetes , cancer , and renal failure .
{ "id": "C0333641", "pos": [ 16, 23 ], "name": "atrophy" }
{ "id": "C0006826", "pos": [ 113, 119 ], "name": "cancer" }
0NA
In only one previously described case has the tumour extended into the pulmonary artery .
{ "id": "C0027651", "pos": [ 46, 52 ], "name": "tumour" }
{ "id": "C0034052", "pos": [ 71, 87 ], "name": "pulmonary artery" }
0NA
We determined the effects of a 3-mo aerobic exercise intervention on basal leg blood flow and alpha-adrenergic vasoconstriction and nitric oxide ( NO ) release in seven apparently healthy middle-aged and older adults ( 60 + /- 3 yr ) .
{ "id": "C0184661", "pos": [ 53, 65 ], "name": "intervention" }
{ "id": "C0232338", "pos": [ 79, 89 ], "name": "blood flow" }
0NA
Baseline assessments included socio-demographic/health information from questionnaires , haemoglobin/anaemia from HemoCue ascertainment of fingerprick blood , and the presence and intensity of STH ( Ascaris lumbricoides , hookworms and Trichuris trichiura ) infections from Kato-Katz examination .
{ "id": "C1261322", "pos": [ 9, 20 ], "name": "assessments" }
{ "id": "C0031809", "pos": [ 284, 295 ], "name": "examination" }
17method_of
In cases 2 and 3 , atropine markedly shortened retrograde fast pathway refractory period and slightly improved antegrade slow pathway conduction .
{ "id": "C0004259", "pos": [ 19, 27 ], "name": "atropine" }
{ "id": "C0025344", "pos": [ 82, 88 ], "name": "period" }
0NA
Use of corticosteroids may be acceptable when lesions are accompanied by edema .
{ "id": "C0221198", "pos": [ 46, 53 ], "name": "lesions" }
{ "id": "C0001617", "pos": [ 7, 22 ], "name": "corticosteroids" }
0NA
We conclude that the determination of the silicon content of tissue by energy-dispersive x-ray analysis is useful in separating the fibrosis due to silicosis from the other causes of pulmonary fibrosis .
{ "id": "C0016059", "pos": [ 132, 140 ], "name": "fibrosis" }
{ "id": "C0034069", "pos": [ 183, 201 ], "name": "pulmonary fibrosis" }
3associated_morphology_of
The review focuses on the prevalence of and risk factors for the chronic form of periodontitis in order better to understand the backgrounds which led to the recognition of the genetic influences on the periodontal disease process .
{ "id": "C0031090", "pos": [ 203, 222 ], "name": "periodontal disease" }
{ "id": "C0031099", "pos": [ 81, 94 ], "name": "periodontitis" }
0NA
The AKI model of crush syndrome was established by intramuscular injection of 50 % glycerol saline solution into thigh ( 8 microL/g ) , while equivalent volume of physiological saline was injected in control group .
{ "id": "C0017861", "pos": [ 83, 91 ], "name": "glycerol" }
{ "id": "C0010392", "pos": [ 17, 31 ], "name": "crush syndrome" }
0NA
The serum levels of ALT , AST , and LDH were further increased in parallel with the deteriorated liver morphological damage ( H&E ) and oxidative stress in celastrol-treated mice , indicating an aggravated liver injury .
{ "id": "C0023884", "pos": [ 97, 102 ], "name": "liver" }
{ "id": "C0160390", "pos": [ 206, 218 ], "name": "liver injury" }
11finding_site_of
To investigate incidence , comorbidities , and impact on health care resources of Clostridium difficile infection after lumbar spine surgery .
{ "id": "C0408578", "pos": [ 120, 140 ], "name": "lumbar spine surgery" }
{ "id": "C0009450", "pos": [ 104, 113 ], "name": "infection" }
0NA
Six episodes of septic arthritis involving 5 patients and eleven joints were documented in the last 7 years in a population receiving 450 patient-years of dialysis treatment .
{ "id": "C0022417", "pos": [ 65, 71 ], "name": "joints" }
{ "id": "C0003869", "pos": [ 16, 32 ], "name": "septic arthritis" }
11finding_site_of
Sixty healthy adult patients of ASA physical status I & II scheduled for elective surgery under general anaesthesia requiring endotracheal intubation were randomly divided into two groups .
{ "id": "C0004057", "pos": [ 32, 35 ], "name": "ASA" }
{ "id": "C0002915", "pos": [ 96, 115 ], "name": "general anaesthesia" }
0NA
Atrophy is blocked by inhibiting adrenal steroid formation and by blocking the actions of excitatory amino acids using Dilantin or NMDA receptor inhibitors .
{ "id": "C0028778", "pos": [ 11, 18 ], "name": "blocked" }
{ "id": "C0002520", "pos": [ 101, 112 ], "name": "amino acids" }
0NA
The 3-month healing rate in gastric ulcer patients treated on an outpatient basis and with no H2 blockers is only some 40 % .
{ "id": "C0043240", "pos": [ 12, 19 ], "name": "healing" }
{ "id": "C0038358", "pos": [ 28, 41 ], "name": "gastric ulcer" }
0NA
Noninvasive techniques including CT scan , MRI , and echocardiography are very useful in the diagnosis of both complications , with contrast aortography remaining the definitive method .
{ "id": "C0024485", "pos": [ 43, 46 ], "name": "MRI" }
{ "id": "C0013516", "pos": [ 53, 69 ], "name": "echocardiography" }
0NA
After plate osteosynthesis the biomechanical principles are not efficient or the circulatory damage delays healing .
{ "id": "C0010957", "pos": [ 93, 99 ], "name": "damage" }
{ "id": "C0043240", "pos": [ 107, 114 ], "name": "healing" }
0NA
We examined the effects of a short-term lifestyle intervention on circulating biomarkers of endothelial health .
{ "id": "C0014257", "pos": [ 92, 103 ], "name": "endothelial" }
{ "id": "C0184661", "pos": [ 50, 62 ], "name": "intervention" }
0NA