text stringlengths 18 770 | h dict | t dict | relation class label 22 classes |
|---|---|---|---|
The sites of origin were the gastroesophageal junction , the colon , the rectum , and the appendix , with the referral diagnosis achalasia , perforated appendix , inflammatory bowel disease , and recurrent lymphoma , respectively . | {
"id": "C0003617",
"pos": [
90,
98
],
"name": "appendix"
} | {
"id": "C0267628",
"pos": [
141,
160
],
"name": "perforated appendix"
} | 11finding_site_of |
The BAER peak latencies were also significantly prolonged in both the ears ; however , the degree of prolongation was more prominent in the right ear . | {
"id": "C0013443",
"pos": [
70,
74
],
"name": "ears"
} | {
"id": "C0079319",
"pos": [
4,
8
],
"name": "BAER"
} | 0NA |
The evaluation of the depth and location of the cannula was performed in real time with the ultrasound , accurately and reliably identifying the planes of fat injection . | {
"id": "C0041618",
"pos": [
92,
102
],
"name": "ultrasound"
} | {
"id": "C0520453",
"pos": [
48,
55
],
"name": "cannula"
} | 0NA |
These findings suggest that , under physiological conditions , cysteine and cystine transport is influenced by the extracellular redox state . | {
"id": "C0010682",
"pos": [
76,
83
],
"name": "cystine"
} | {
"id": "C0010654",
"pos": [
63,
71
],
"name": "cysteine"
} | 16is_modification_of |
Whether the damage is caused by the expansion and lysing of the cell membrane by these two lipophilic drugs , or by increased intracellular calcium to toxic levels is not yet known . | {
"id": "C0010957",
"pos": [
12,
18
],
"name": "damage"
} | {
"id": "C0006675",
"pos": [
140,
147
],
"name": "calcium"
} | 0NA |
When THC-blocked proestrous rats were subjected to unilateral electrochemical stimulation ( 100 microA anodal DC for 45 s ) in the medial preoptic area ( mPOA ) , serum LH was significantly elevated at 30 , 60 and 90 min after stimulation in comparison with LH levels measured in sham-stimulated control animals at those times . | {
"id": "C1292856",
"pos": [
227,
238
],
"name": "stimulation"
} | {
"id": "C0175313",
"pos": [
131,
151
],
"name": "medial preoptic area"
} | 0NA |
Computerized tomography suggested an intrapulmonary location of the mass with extension to the apical pleura . | {
"id": "C0577559",
"pos": [
68,
72
],
"name": "mass"
} | {
"id": "C0040405",
"pos": [
0,
23
],
"name": "Computerized tomography"
} | 0NA |
The sensation of sharpness was more pronounced up to 2 cm outside the flare zone for at least 16 min following the injection ( tested with a 200 mN von Frey probe ) . | {
"id": "C0021485",
"pos": [
115,
124
],
"name": "injection"
} | {
"id": "C0036658",
"pos": [
4,
13
],
"name": "sensation"
} | 0NA |
In 21 of these 85 specimens , there was histologic proof of invasion of the cochlear nerve by the tumor . | {
"id": "C0027651",
"pos": [
98,
103
],
"name": "tumor"
} | {
"id": "C0009201",
"pos": [
76,
90
],
"name": "cochlear nerve"
} | 0NA |
These advances provide valuable insights into the mechanism of substrate recruitment and processing preceding their destruction in the 20S core particle . | {
"id": "C1261381",
"pos": [
116,
127
],
"name": "destruction"
} | {
"id": "C0271510",
"pos": [
73,
84
],
"name": "recruitment"
} | 0NA |
The appearance of the epithelium of the external genitalia is used to identify the stage of the estrous cycle of a female mouse . | {
"id": "C0014609",
"pos": [
22,
32
],
"name": "epithelium"
} | {
"id": "C0042993",
"pos": [
40,
58
],
"name": "external genitalia"
} | 0NA |
In conclusion , ileal bacterial populations and fermentation patterns are susceptible to changes in the intestinal availability of Ca and P as well as to the supply of pectin as a fermentable substrate . | {
"id": "C0021853",
"pos": [
104,
114
],
"name": "intestinal"
} | {
"id": "C0020885",
"pos": [
16,
21
],
"name": "ileal"
} | 0NA |
The low rate of recurrent ulcer ( 3 % ) suggests that PCV is an effective operation . | {
"id": "C0543467",
"pos": [
74,
83
],
"name": "operation"
} | {
"id": "C0018935",
"pos": [
54,
57
],
"name": "PCV"
} | 0NA |
During the operation a large scleral rupture , 1 mm from the limbus , a prolapsed iris , vitreous , and the lens were found under the conjunctiva . | {
"id": "C0023317",
"pos": [
108,
112
],
"name": "lens"
} | {
"id": "C0339200",
"pos": [
29,
44
],
"name": "scleral rupture"
} | 0NA |
Assessment included measures of PTSD , sleep , depression , anger , guilt , and social isolation , administered at post-treatment , 3-month , and 6-month follow-up . | {
"id": "C0031809",
"pos": [
0,
10
],
"name": "Assessment"
} | {
"id": "C0037313",
"pos": [
39,
44
],
"name": "sleep"
} | 0NA |
In adult male rats , a single oral dose of 10 mg/kg of PNU 157706 caused a marked and longer lasting reduction of prostatic DHT than did finasteride ( at 24 h inhibition by 89 and 47 % , respectively ) . | {
"id": "C0033572",
"pos": [
114,
123
],
"name": "prostatic"
} | {
"id": "C0086582",
"pos": [
9,
13
],
"name": "male"
} | 0NA |
Pharmacokinetic parameters show that continuous infusion is better than an intermittent schedule in maintaining minimal virostatic concentrations of the drug with a lower daily dose . | {
"id": "C0013227",
"pos": [
153,
157
],
"name": "drug"
} | {
"id": "C0574032",
"pos": [
48,
56
],
"name": "infusion"
} | 0NA |
We found the testes of transgenic mice to be significantly smaller than those of wild-type males and histological analysis showed massive degeneration of the seminiferous epithelium . | {
"id": "C0011164",
"pos": [
138,
150
],
"name": "degeneration"
} | {
"id": "C0021358",
"pos": [
13,
19
],
"name": "testes"
} | 0NA |
Normalized tumor markers designate the phase of discussion on surgical indications . | {
"id": "C0027651",
"pos": [
11,
16
],
"name": "tumor"
} | {
"id": "C0557061",
"pos": [
48,
58
],
"name": "discussion"
} | 0NA |
We used human osteosarcoma cells ( MG-63 ) and measured hVDR and GR mRNA levels after androgen , estrogen , glucocorticoid , progesterone , thyroid hormone , vitamin A and vitamin D treatments . | {
"id": "C0042839",
"pos": [
158,
167
],
"name": "vitamin A"
} | {
"id": "C0087111",
"pos": [
182,
192
],
"name": "treatments"
} | 0NA |
Tumor responses under the renal capsule to radiation were well correlated with the known radiosensitivities of the tumors . | {
"id": "C0027651",
"pos": [
115,
121
],
"name": "tumors"
} | {
"id": "C0227616",
"pos": [
26,
39
],
"name": "renal capsule"
} | 0NA |
In total , 195 adenomas and six cancers were detected among 85 individuals . | {
"id": "C0006826",
"pos": [
32,
39
],
"name": "cancers"
} | {
"id": "C0001430",
"pos": [
15,
23
],
"name": "adenomas"
} | 0NA |
Conventional orthopedic and neurological examination along with motion palpation are the cornerstones of physical examination . | {
"id": "C0031809",
"pos": [
105,
125
],
"name": "physical examination"
} | {
"id": "C0027853",
"pos": [
28,
52
],
"name": "neurological examination"
} | 17method_of |
Iron has been quantified in pharmaceutical preparations by developing red spots pursuant to interaction of Fe(II ) ions in the sample with 1 , 10-phenanthroline on TLC plate . | {
"id": "C0013227",
"pos": [
28,
55
],
"name": "pharmaceutical preparations"
} | {
"id": "C0302583",
"pos": [
0,
4
],
"name": "Iron"
} | 0NA |
We aimed to test the hypotheses that spleen enlarges over time in cirrhosis , and that a progressive enlargement may be associated with portal hypertension-related events . | {
"id": "C0020564",
"pos": [
101,
112
],
"name": "enlargement"
} | {
"id": "C0023890",
"pos": [
66,
75
],
"name": "cirrhosis"
} | 0NA |
All these drugs elicit adverse side effects , which represent a challenge for antitumor chemotherapy . | {
"id": "C0013227",
"pos": [
10,
15
],
"name": "drugs"
} | {
"id": "C0013216",
"pos": [
88,
100
],
"name": "chemotherapy"
} | 10direct_substance_of |
A significant fall in serum potassium from 4.24 to 3.77 and 3.92 mmol/l occurred with the combined two drugs but not the combination of three . | {
"id": "C0013227",
"pos": [
103,
108
],
"name": "drugs"
} | {
"id": "C0302353",
"pos": [
22,
37
],
"name": "serum potassium"
} | 0NA |
By the preoperative and intraoperative imaging managements conducted , combined resection of the aberrant right hepatic artery without anastomosis was achieved by pancreaticoduodenectomy for pancreas head cancer . | {
"id": "C0030274",
"pos": [
191,
199
],
"name": "pancreas"
} | {
"id": "C0085162",
"pos": [
163,
186
],
"name": "pancreaticoduodenectomy"
} | 9direct_procedure_site_of |
This review addresses the clinical picture of rheumatic diseases seen in Whipple 's disease , gluten-sensitive enteropathy , pseudomembranous colitis , collagenous colitis and that developing after enteric infections and intestinal bypass operations for morbid obesity . | {
"id": "C0021853",
"pos": [
221,
231
],
"name": "intestinal"
} | {
"id": "C0007570",
"pos": [
94,
122
],
"name": "gluten-sensitive enteropathy"
} | 11finding_site_of |
Only 20/41 ( 48.8 % ) with prior bladder augmentation , urinary channel , and MACE transitioned . | {
"id": "C0005682",
"pos": [
33,
40
],
"name": "bladder"
} | {
"id": "C1293122",
"pos": [
41,
53
],
"name": "augmentation"
} | 0NA |
Owing the difficulty to study the aetiology of thrombocytosis in human models , we employed acute and chronic free drug interventions in order to identify these two types of this important disease in laboratory animals . | {
"id": "C0836924",
"pos": [
47,
61
],
"name": "thrombocytosis"
} | {
"id": "C0012634",
"pos": [
189,
196
],
"name": "disease"
} | 0NA |
We present two infants with brain tumours who developed torticollis and further neurological findings such as ataxia and reflex differences . | {
"id": "C0422837",
"pos": [
80,
101
],
"name": "neurological findings"
} | {
"id": "C0034929",
"pos": [
121,
127
],
"name": "reflex"
} | 0NA |
Early diagnosis and therapy are necessary before dislocation , cord compression , and subsequent neurologic impairment occur . | {
"id": "C0012691",
"pos": [
49,
60
],
"name": "dislocation"
} | {
"id": "C0037926",
"pos": [
63,
79
],
"name": "cord compression"
} | 0NA |
Removal of these false positive identifications necessarily involves a trade-off between sensitivity and specificity . | {
"id": "C0015252",
"pos": [
0,
7
],
"name": "Removal"
} | {
"id": "C0020517",
"pos": [
89,
100
],
"name": "sensitivity"
} | 0NA |
After marking the carbohydrate-lectin binding events by 13 nm peptide-stabilized gold nanoparticles through the biotin-avidin reaction , the 3D microarray can be directly detected by the RLS scanner without the conventional silver enhancement step . | {
"id": "C0037125",
"pos": [
224,
230
],
"name": "silver"
} | {
"id": "C0018026",
"pos": [
81,
85
],
"name": "gold"
} | 0NA |
The early diagnosis of acute myocardial infarction ( AMI ) can be particularly challenging in patients with known coronary artery disease ( CAD ) due to pre-existing ECG changes and chronic increases in cardiac troponin ( cTn ) levels . | {
"id": "C0027051",
"pos": [
53,
56
],
"name": "AMI"
} | {
"id": "C0010054",
"pos": [
114,
137
],
"name": "coronary artery disease"
} | 0NA |
The authors further note a possible ' suppress effect ' in that a negative relationship between DWI arrests and high-risk driving is concealed by problem drinking . | {
"id": "C0205160",
"pos": [
66,
74
],
"name": "negative"
} | {
"id": "C0598801",
"pos": [
96,
99
],
"name": "DWI"
} | 0NA |
Median recoveries of drug in dialysate were 9 % ( INH ) , 4 % ( RIF ) , 45 % ( PZA ) , and 2 % ( EMB ) of the doses administered . | {
"id": "C0013227",
"pos": [
21,
25
],
"name": "drug"
} | {
"id": "C0035608",
"pos": [
64,
67
],
"name": "RIF"
} | 0NA |
Fixation of the neck into the zirconia head , with no mismatching or stress differences , would solve the fatigue-induced head destruction . | {
"id": "C0027530",
"pos": [
16,
20
],
"name": "neck"
} | {
"id": "C0185023",
"pos": [
0,
8
],
"name": "Fixation"
} | 0NA |
The application described in this study appears to be accurate and valid , thus allowing calculation of a hearing handicap and assessment of the pure-tone air conduction threshold with iPhone/iPad devices . | {
"id": "C0031809",
"pos": [
127,
137
],
"name": "assessment"
} | {
"id": "C0185125",
"pos": [
4,
15
],
"name": "application"
} | 0NA |
The present 1H NMR investigation of adrenodoxin demonstrates that a conformational change upon reduction of the iron-sulfur cluster occurs in the sequence of negatively charged amino acids that is a putative site for interaction with redox partners . | {
"id": "C0002520",
"pos": [
177,
188
],
"name": "amino acids"
} | {
"id": "C0037420",
"pos": [
217,
228
],
"name": "interaction"
} | 0NA |
Prenatal screening by ultrasonography or amniocentesis before 24 weeks of gestation , | {
"id": "C0041618",
"pos": [
22,
37
],
"name": "ultrasonography"
} | {
"id": "C0002627",
"pos": [
41,
54
],
"name": "amniocentesis"
} | 0NA |
We describe five affected individuals with similar dysmorphic facies , and three of them had either complete situs inversus , dextrocardia , or transposition of the great arteries ; similar cardiac abnormalities were previously identified in a mouse mutant for the orthologous Megf8 . | {
"id": "C0003842",
"pos": [
171,
179
],
"name": "arteries"
} | {
"id": "C0037221",
"pos": [
109,
123
],
"name": "situs inversus"
} | 0NA |
In the management of clinical low back pain ( LBP ) , actual damage to lower back areas such as muscles , intervertebral discs etc . are normally targeted for therapy . | {
"id": "C0010957",
"pos": [
61,
67
],
"name": "damage"
} | {
"id": "C0021815",
"pos": [
106,
126
],
"name": "intervertebral discs"
} | 0NA |
Pyothorax-associated lymphoma ( PAL ) is a non-Hodgkin 's lymphoma developing in the pleural cavity after a long-standing history of pyothorax . | {
"id": "C0178802",
"pos": [
85,
99
],
"name": "pleural cavity"
} | {
"id": "C0014013",
"pos": [
133,
142
],
"name": "pyothorax"
} | 11finding_site_of |
Pancreaticobiliary maljunction was diagnosed in 75 % on MRCP based on the finding of an anomalous union between the common bile duct and the pancreatic duct and the existence of a long common channel . | {
"id": "C0005400",
"pos": [
123,
132
],
"name": "bile duct"
} | {
"id": "C0994163",
"pos": [
56,
60
],
"name": "MRCP"
} | 9direct_procedure_site_of |
From this series , we conclude that detailed clinical data together with some simple markers such as IL 6 levels seem sufficient to provide clinicians with presumptive information on the condition of the immune system and to allow for initial prediction of vaccination efficiency . | {
"id": "C0020962",
"pos": [
204,
217
],
"name": "immune system"
} | {
"id": "C0012634",
"pos": [
187,
196
],
"name": "condition"
} | 0NA |
Angiography of coronary arteries and aortas were done to obtain a standard model of vascular geometry . | {
"id": "C0003483",
"pos": [
37,
43
],
"name": "aortas"
} | {
"id": "C0002978",
"pos": [
0,
11
],
"name": "Angiography"
} | 0NA |
The lesion-induced degenerative changes were most pronounced in the lateral parts of the ipsilateral substantia nigra and striatum . | {
"id": "C0011164",
"pos": [
19,
31
],
"name": "degenerative"
} | {
"id": "C0038590",
"pos": [
101,
117
],
"name": "substantia nigra"
} | 0NA |
The potential role of cellular immunotherapy and , more particularly , of LANAK cells as an effective procedure to further reduce tumour burden in patients responsive to IL2 will have to be assessed in randomised studies . | {
"id": "C0021756",
"pos": [
170,
173
],
"name": "IL2"
} | {
"id": "C0184661",
"pos": [
102,
111
],
"name": "procedure"
} | 0NA |
Of the patients , 15 had cardiovascular complications ( Group A ) ; 12 did not ( Group B ) . | {
"id": "C0007226",
"pos": [
25,
39
],
"name": "cardiovascular"
} | {
"id": "C0348801",
"pos": [
81,
88
],
"name": "Group B"
} | 0NA |
Anatomical categorisation of subglottic stenosis guides surgical procedure selection . | {
"id": "C0543467",
"pos": [
56,
74
],
"name": "surgical procedure"
} | {
"id": "C0238441",
"pos": [
29,
48
],
"name": "subglottic stenosis"
} | 0NA |
Independent tests on eleven common drugs between CCLE and CGP achieved satisfactory performance for three of them , i.e. , AZD6244 , Erlotinib and PD-0325901 , using expression levels of only twelve , six and seven genes , respectively . | {
"id": "C0013227",
"pos": [
35,
40
],
"name": "drugs"
} | {
"id": "C1135135",
"pos": [
133,
142
],
"name": "Erlotinib"
} | 0NA |
Blood flow velocities , volume flow rates , and wall shear stress ( WSS ) were established in carotid arteries from models of eCEA and exeCEA with included increasing groove ( 1 , 1.5 , 2 , and 2.5 mm ) at the " incision line " , under input pressure of 120 and 150 mm Hg . | {
"id": "C0007272",
"pos": [
94,
110
],
"name": "carotid arteries"
} | {
"id": "C0232338",
"pos": [
0,
10
],
"name": "Blood flow"
} | 0NA |
Subchronic treatment with MAP ( 4.6 mg/kg , i.p . , once daily for 11 days ) significantly decreased the Kd , but not Bmax , values of [3H]1,3-dipropyl-8-cyclopentylxanthine ( [3H]DPCPX ) binding to adenosine A1 receptors in the prefrontal cortex and hippocampus , but not striatum , of rat brain . | {
"id": "C0006104",
"pos": [
291,
296
],
"name": "brain"
} | {
"id": "C0010097",
"pos": [
273,
281
],
"name": "striatum"
} | 0NA |
Because of the elimination of many infectious diseases with vaccines , chronic illnesses account for six of the top ten causes of death . | {
"id": "C0008679",
"pos": [
71,
88
],
"name": "chronic illnesses"
} | {
"id": "C0009450",
"pos": [
35,
54
],
"name": "infectious diseases"
} | 0NA |
For the fattening period from 200 to 650 kg of live mass mean contents of 151.5 g calcium , 71.3 g phosphorus , 3.2 g magnesium , 5.1 g sodium and 1.1 g potassium per kg DM were analysed . | {
"id": "C0024467",
"pos": [
118,
127
],
"name": "magnesium"
} | {
"id": "C0006675",
"pos": [
82,
89
],
"name": "calcium"
} | 0NA |
Coexpression of dominant negative versions of kinases of the JNK pathway , such as catalytically inactive forms of MEKK1 , MKK7 , and JNKK , and of cytoplasmic JNK-inhibitor JIP-1 , as well as treatment of cells with curcumin ( which blocks JNK activation by MNNG ) , inhibited MNNG-induced uPA transcriptional activity . | {
"id": "C0028778",
"pos": [
234,
240
],
"name": "blocks"
} | {
"id": "C0010467",
"pos": [
217,
225
],
"name": "curcumin"
} | 0NA |
TCS also promoted the vigorous proliferation of antigen-specific effector T cells , markedly increased Th1 cytokine secretion and elicited more memory T cells in tumor-bearing mice , consequently enhancing the anti-tumor response and inducing immune protection . | {
"id": "C0334094",
"pos": [
31,
44
],
"name": "proliferation"
} | {
"id": "C0242387",
"pos": [
0,
3
],
"name": "TCS"
} | 0NA |
One of the essential purposes of intervention programmes for people with profound intellectual disabilities ( ID ) is to enhance the desirable mood and behaviour and decrease the undesirable ones through stabilizing their emotion . | {
"id": "C3714756",
"pos": [
82,
107
],
"name": "intellectual disabilities"
} | {
"id": "C0013987",
"pos": [
222,
229
],
"name": "emotion"
} | 0NA |
The purpose of this study was to examine the epiphyseal scar and its relationship to the intercondylar notch on anteroposterior ( AP ) radiographs of the knee and to establish its usefulness with retrograde femoral nail insertion . | {
"id": "C0021107",
"pos": [
220,
229
],
"name": "insertion"
} | {
"id": "C1306645",
"pos": [
135,
146
],
"name": "radiographs"
} | 0NA |
CS increases inflammation , thrombosis , and oxidation of low-density lipoproteins . | {
"id": "C0021368",
"pos": [
13,
25
],
"name": "inflammation"
} | {
"id": "C0040053",
"pos": [
28,
38
],
"name": "thrombosis"
} | 0NA |
A gas chromatography-mass spectrometry method was employed for qualitative determination of the metabolites in blood of rats by injection or oral administration of volatile oil in Houttuyniae Herba and of 2-undecanone , which were compared with the differences between binary two drugs as well as two administration . | {
"id": "C0013227",
"pos": [
280,
285
],
"name": "drugs"
} | {
"id": "C0001563",
"pos": [
141,
160
],
"name": "oral administration"
} | 10direct_substance_of |
In addition , future anthropogenic warming would robustly increase the wind speed and rainfall of 11 of 13 intense tropical cyclones ( of 15 events sampled globally ) . | {
"id": "C0441621",
"pos": [
148,
155
],
"name": "sampled"
} | {
"id": "C0016204",
"pos": [
71,
75
],
"name": "wind"
} | 0NA |
In the ligand-based technique such as saturation transfer difference ( STD ) and WaterLOGSY , only the NMR signals of the ligands are observed . | {
"id": "C0024485",
"pos": [
103,
106
],
"name": "NMR"
} | {
"id": "C0036916",
"pos": [
71,
74
],
"name": "STD"
} | 0NA |
After surgery , visual acuity was 20/40 or better in 79 % of operated eyes . | {
"id": "C0015392",
"pos": [
70,
74
],
"name": "eyes"
} | {
"id": "C0042812",
"pos": [
16,
29
],
"name": "visual acuity"
} | 0NA |
A diagnosis of unilateral tuberculosis of the conjunctiva was established in a 75-year-old female patient eight years after the first manifestations of disease . | {
"id": "C0009758",
"pos": [
46,
57
],
"name": "conjunctiva"
} | {
"id": "C0041296",
"pos": [
26,
38
],
"name": "tuberculosis"
} | 0NA |
The frequency of polypharmacy was 54.5 % , urinary incontinence 47.6 % , malnutrition 9.6 % , depression 35.1 % , dementia 21.6 % , falls 33.6 % , sarcopenia 31.7 % , and frailty 28.3 % . | {
"id": "C0162429",
"pos": [
73,
85
],
"name": "malnutrition"
} | {
"id": "C0872084",
"pos": [
147,
157
],
"name": "sarcopenia"
} | 0NA |
This procedure produced a near homogeneous enzyme preparation with a yield of 70 % . | {
"id": "C0014442",
"pos": [
43,
49
],
"name": "enzyme"
} | {
"id": "C0184661",
"pos": [
5,
14
],
"name": "procedure"
} | 0NA |
Training on the handheld equipment and applications should include assessment of systems connectivity and integration , access authority , existing skills , and previous use . | {
"id": "C0031809",
"pos": [
67,
77
],
"name": "assessment"
} | {
"id": "C0185125",
"pos": [
39,
51
],
"name": "applications"
} | 0NA |
There is a statistical significant correlation between the Cd and Pb contents in liver and kidney . | {
"id": "C0022646",
"pos": [
91,
97
],
"name": "kidney"
} | {
"id": "C0023884",
"pos": [
81,
86
],
"name": "liver"
} | 0NA |
Wilson disease ( WD ) is a genetic disorder in which excess toxic copper accumulates in the liver , brain , and other tissues leading to severe and life-threatening symptoms . | {
"id": "C0023884",
"pos": [
92,
97
],
"name": "liver"
} | {
"id": "C0019202",
"pos": [
0,
14
],
"name": "Wilson disease"
} | 11finding_site_of |
Rat quiescin/sulphydryl oxidase ( rQSOX ) introduces disulphide bridges into peptides and proteins with the reduction of molecular oxygen to hydrogen peroxide . | {
"id": "C0020281",
"pos": [
141,
158
],
"name": "hydrogen peroxide"
} | {
"id": "C0030956",
"pos": [
77,
85
],
"name": "peptides"
} | 0NA |
Ablation of syndecan-1 in mice led to unopposed progression of liver injury upon APAP overdose . | {
"id": "C0547070",
"pos": [
0,
8
],
"name": "Ablation"
} | {
"id": "C0029944",
"pos": [
86,
94
],
"name": "overdose"
} | 0NA |
On other days , an alternately flavored ( CS- ) solution , e.g. , grape-water , was paired with IG infusions of water . | {
"id": "C0574032",
"pos": [
99,
108
],
"name": "infusions"
} | {
"id": "C0043047",
"pos": [
112,
117
],
"name": "water"
} | 0NA |
Animals were sacrificed 6 days after CP ( or vehicle ) treatment , and blood , urine , and kidneys were obtained , prepared for light microscopy evaluation , lipid peroxidation content and laboratory analysis . | {
"id": "C0022646",
"pos": [
91,
98
],
"name": "kidneys"
} | {
"id": "C0430389",
"pos": [
128,
144
],
"name": "light microscopy"
} | 0NA |
The Hsp90α protein predominates in the brain and testis , and its role in spermatogenesis has been described in several species . | {
"id": "C0039597",
"pos": [
49,
55
],
"name": "testis"
} | {
"id": "C0006104",
"pos": [
39,
44
],
"name": "brain"
} | 0NA |
The anatomy of the perineum and pelvis is complex . | {
"id": "C0031066",
"pos": [
19,
27
],
"name": "perineum"
} | {
"id": "C0030797",
"pos": [
32,
38
],
"name": "pelvis"
} | 0NA |
Dentin formed the bulk of the tumors . | {
"id": "C0027651",
"pos": [
30,
36
],
"name": "tumors"
} | {
"id": "C0011429",
"pos": [
0,
6
],
"name": "Dentin"
} | 0NA |
The similarity of these electrocardiographic changes to those produced by myocardial infarction that we observed in humans suggests that more severe injury to the myocardium at the anterior septum and anterior left ventricular wall may be important in the pathogenesis of anthracycline cardiomyopathy . | {
"id": "C0027061",
"pos": [
163,
173
],
"name": "myocardium"
} | {
"id": "C0027051",
"pos": [
74,
95
],
"name": "myocardial infarction"
} | 11finding_site_of |
Laboratory exposures of reference site fish to a model PAH ( 3-methylcholanthrene ) , however , produced no increase in liver Pgp levels as measured by immunoblot . | {
"id": "C0023884",
"pos": [
120,
125
],
"name": "liver"
} | {
"id": "C0030123",
"pos": [
55,
58
],
"name": "PAH"
} | 0NA |
Chronic levels of severe maternal depression placed children at increased risk of concurrent injury from birth to age 3 . | {
"id": "C0205082",
"pos": [
18,
24
],
"name": "severe"
} | {
"id": "C0005615",
"pos": [
105,
110
],
"name": "birth"
} | 0NA |
Activities to increase cancer screening in this population may not be informed by Hispanics , which may have implications for success rates of interventions . | {
"id": "C0006826",
"pos": [
23,
29
],
"name": "cancer"
} | {
"id": "C0199230",
"pos": [
30,
39
],
"name": "screening"
} | 12focus_of |
A morphometric study of contusion injuries of the cat thoracic cord indicates that the major determinant of axon disruption is the extrusion of tissue from the impact site , due to viscoelastic distortion of the parenchyma within the meningeal tube . | {
"id": "C0009938",
"pos": [
24,
33
],
"name": "contusion"
} | {
"id": "C0040300",
"pos": [
144,
150
],
"name": "tissue"
} | 0NA |
Pulmonary fibrosis is a progressive scarring disorder of the lung with dismal prognosis and no curative therapy . | {
"id": "C0024109",
"pos": [
61,
65
],
"name": "lung"
} | {
"id": "C0034069",
"pos": [
0,
18
],
"name": "Pulmonary fibrosis"
} | 11finding_site_of |
Nucleoside-based inhibitors of reverse transcriptase were the first drugs to be used in the chemotherapy of AIDS . | {
"id": "C0013227",
"pos": [
68,
73
],
"name": "drugs"
} | {
"id": "C0013216",
"pos": [
92,
104
],
"name": "chemotherapy"
} | 10direct_substance_of |
This exploratory study sought to assess these changes in patients with recent wrist and ankle fractures . | {
"id": "C0043262",
"pos": [
78,
83
],
"name": "wrist"
} | {
"id": "C0159877",
"pos": [
88,
103
],
"name": "ankle fractures"
} | 0NA |
Taken altogether , these results indicate the CB , particularly its epithelium , as one of the possible sources of the ocular intrinsic ceruloplasmin . | {
"id": "C0015392",
"pos": [
119,
125
],
"name": "ocular"
} | {
"id": "C0014609",
"pos": [
68,
78
],
"name": "epithelium"
} | 0NA |
Antihypertensive use and echocardiographic parameters including chamber volumes and left ventricular mass and LA peak negative and positive strain and strain rate were compared between groups . | {
"id": "C1446409",
"pos": [
131,
139
],
"name": "positive"
} | {
"id": "C0080194",
"pos": [
140,
146
],
"name": "strain"
} | 0NA |
We report on the prenatal imaging findings and perinatal management of a fetus with MCDK unusually presenting as a single predominant large cyst , erroneously interpreted as a severe fetal hydronephrosis . | {
"id": "C0010709",
"pos": [
140,
144
],
"name": "cyst"
} | {
"id": "C2315709",
"pos": [
183,
203
],
"name": "fetal hydronephrosis"
} | 0NA |
These results suggest a possible role for the cytotoxic molecule MBP in the evolution of lesions of chronic urticaria . | {
"id": "C0221198",
"pos": [
89,
96
],
"name": "lesions"
} | {
"id": "C0263338",
"pos": [
100,
117
],
"name": "chronic urticaria"
} | 0NA |
In fibrosis , where the myofibroblasts are the major participant , halofuginone can be used as a single therapy , whereas in cancer it should be considered in combination with other therapies that affect the tumor cells via different modalities . | {
"id": "C0016059",
"pos": [
3,
11
],
"name": "fibrosis"
} | {
"id": "C0006826",
"pos": [
125,
131
],
"name": "cancer"
} | 0NA |
In this patient , the use of a collagen sponge filled with gentamicin was effective in preventing infection and promoting healing of multiple full-thickness pressure ulcers . | {
"id": "C0009325",
"pos": [
31,
39
],
"name": "collagen"
} | {
"id": "C0009450",
"pos": [
98,
107
],
"name": "infection"
} | 0NA |
No interaction between the two organisms was detected at the stage of initial adherence to the tooth surfaces or during the first 24 h of growth . | {
"id": "C0442726",
"pos": [
45,
53
],
"name": "detected"
} | {
"id": "C0037420",
"pos": [
3,
14
],
"name": "interaction"
} | 0NA |
Therefore , signaling through Notch is not required for SC quiescence in the healthy epithelium or to initiate HC regeneration after damage . | {
"id": "C0010957",
"pos": [
133,
139
],
"name": "damage"
} | {
"id": "C0014609",
"pos": [
85,
95
],
"name": "epithelium"
} | 0NA |
Infusion of oyster glycogen every 3 d for 30 d in four ewes elicited similar changes in milk somatic cell count and mammary histology . | {
"id": "C0006141",
"pos": [
116,
123
],
"name": "mammary"
} | {
"id": "C0574032",
"pos": [
0,
8
],
"name": "Infusion"
} | 0NA |
The clot is withdrawn from the syringe by retrieving the embolus and the formed material is introduced in formol and processed as usual for histology . | {
"id": "C1704212",
"pos": [
57,
64
],
"name": "embolus"
} | {
"id": "C0009074",
"pos": [
4,
8
],
"name": "clot"
} | 0NA |
The involved joints are the interphalangeal joint of the thumb , patellofemoral joint , and ankle joint . | {
"id": "C0447801",
"pos": [
65,
85
],
"name": "patellofemoral joint"
} | {
"id": "C0040067",
"pos": [
57,
62
],
"name": "thumb"
} | 0NA |
Lesions occurred roughly equally in primary ( 47 % ) and secondary ( 53 % ) hyperparathyroidism . | {
"id": "C0221198",
"pos": [
0,
7
],
"name": "Lesions"
} | {
"id": "C0020502",
"pos": [
76,
95
],
"name": "hyperparathyroidism"
} | 0NA |
C3 KO mice after active immunization with cross-protective nonneutralizing M2e-based vaccine were not protected against influenza virus , although low levels of M2e-specific antibodies were protective after passive coadministration with virus in wild-type mice . | {
"id": "C0020971",
"pos": [
24,
36
],
"name": "immunization"
} | {
"id": "C0042210",
"pos": [
85,
92
],
"name": "vaccine"
} | 0NA |
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