query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'ched'? | [
"ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens))"
] | [
"ched1 (homo sapiens)",
"ched-related (drosophila melanogaster)",
"chegdd (homo sapiens)",
"ched (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'An antisense oligodeoxynucleotide designed to interrupt CHED's expression (AS-CHED) significantly reduced the ratio between CHED mRNA and actin mRNA within 1 hr of its addition to cultures, a reduction that persisted for 4 days.', answer the user's query. |
What is the biomedical concept corresponding to 'ched'? | [
"ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens))"
] | [
"ched1 (homo sapiens)",
"ched-related (drosophila melanogaster)",
"chegdd (homo sapiens)",
"ched (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'AS-CHED treatment selectively inhibited megakaryocyte development in murine bone marrow cultures but did not prevent other hematopoietic pathways, as evidenced by increasing numbers of mononuclear cells.', answer the user's query. |
What is the biomedical concept corresponding to 'butyrylcholinesterase'? | [
"butyrylcholinesterase (homo sapiens)",
"che1 (homo sapiens) (butyrylcholinesterase (homo sapiens))",
"e1 (homo sapiens) (butyrylcholinesterase (homo sapiens))"
] | [
"butyrylcholinesterase (bos taurus)",
"butyrylcholinesterase (mus musculus)",
"butyrylcholinesterase (rattus norvegicus)",
"butyrylcholinesterase (oryctolagus cuniculus)"
] | Given the context 'An oligodeoxynucleotide blocking production of the acetylcholine-hydrolyzing enzyme, butyrylcholinesterase, displayed a similar inhibition of megakaryocytopoiesis.', answer the user's query. |
What is the biomedical concept corresponding to 'cdc2'? | [
"p34cdc2 (homo sapiens)",
"cdc2 (homo sapiens) (cyclin dependent kinase 1 (homo sapiens))"
] | [
"cdc2 (saccharomyces cerevisiae s288c)",
"cdc2 (homo sapiens) (dna polymerase delta 1, catalytic subunit (homo sapiens))",
"cdc28 (saccharomyces cerevisiae s288c)",
"cdc21 (saccharomyces cerevisiae s288c)"
] | Given the context 'In contrast, an oligodeoxynucleotide blocking production of the human 2Hs cdc2 homolog interfered with production of the human 2Hs cdc2 homolog interfered with cellular proliferation without altering the cell-type composition of these cultures.', answer the user's query. |
What is the biomedical concept corresponding to 'cdc2'? | [
"p34cdc2 (homo sapiens)",
"cdc2 (homo sapiens) (cyclin dependent kinase 1 (homo sapiens))"
] | [
"cdc2 (saccharomyces cerevisiae s288c)",
"cdc2 (homo sapiens) (dna polymerase delta 1, catalytic subunit (homo sapiens))",
"cdc28 (saccharomyces cerevisiae s288c)",
"cdc21 (saccharomyces cerevisiae s288c)"
] | Given the context 'In contrast, an oligodeoxynucleotide blocking production of the human 2Hs cdc2 homolog interfered with production of the human 2Hs cdc2 homolog interfered with cellular proliferation without altering the cell-type composition of these cultures.', answer the user's query. |
What is the biomedical concept corresponding to 'ched'? | [
"ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens))"
] | [
"ched1 (homo sapiens)",
"ched-related (drosophila melanogaster)",
"chegdd (homo sapiens)",
"ched (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'Therefore, these findings strengthen the link between cholinergic signaling and cell division control in hematopoiesis and implicate both CHED and cholinesterases in this differentiation process.', answer the user's query. |
What is the biomedical concept corresponding to 'desmoglein i'? | [
"desmoglein 1 (homo sapiens)",
"dsg1 (homo sapiens)"
] | [
"desmoglein 3 (homo sapiens)",
"desmoglein 2 (homo sapiens)",
"desmoglein 4 (homo sapiens)",
"desmoglein 1 (sus scrofa)"
] | Given the context 'The transmembrane desmosomal glycoproteins have been proposed to play a role in cell adhesion; desmoglein I (DGI) is a major member of this class of desmosomal molecules.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'The transmembrane desmosomal glycoproteins have been proposed to play a role in cell adhesion; desmoglein I (DGI) is a major member of this class of desmosomal molecules.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'However, evidence supporting a role for DGI in cell adhesion or in the plaque is lacking.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'In order to begin to understand DGI function we have identified human cDNA clones encoding the entire mature polypeptide of 1000 amino acids.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'Our data suggest that like the bovine DGI molecule human DGI is highly related to the calcium-dependent class of cell adhesion molecules known as cadherins.', answer the user's query. |
What is the biomedical concept corresponding to 'n-cadherin'? | [
"cdhn (homo sapiens)"
] | [
"n-cad (drosophila melanogaster) (cadherin-n (drosophila melanogaster))",
"d-cad (drosophila melanogaster) (cadherin-n (drosophila melanogaster))",
"cadherin 1 (homo sapiens)",
"cdh1 (homo sapiens) (cadherin 1 (homo sapiens))"
] | Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', answer the user's query. |
What is the biomedical concept corresponding to 'dgi'? | [
"dg1 (homo sapiens)"
] | [
"dgi1 (homo sapiens)",
"dgi (mus musculus)",
"dgs-i (homo sapiens)",
"dgsi (homo sapiens)"
] | Given the context 'Five amino acids that are identical in bovine and human DGI lie in the second of the two predicted beta-strands, and intriguingly contain putative target sites for protein kinase C.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'Characterization of human loricrin.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'We have isolated and characterized a full-length cDNA clone encoding human loricrin.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (mus musculus)"
] | [
"loricrin (homo sapiens)",
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)"
] | Given the context 'Curiously, this protein displays major differences from the recently described mouse loricrin (Mehrel, T., Hohl, D., Nakazawa, H., Rothnagel, J.A., Longley, M.A., Bundman, D., Cheng, C.K., Lichti, U., Bisher, M.E., Steven, A. C., Steinert, P.M., Yuspa, S.H., and Roop, D.R. (1990)', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'Furthermore, we have isolated four peptides from purified human cell envelopes that contain recognizable loricrin sequences and which are cross-linked by the N epsilon-(gamma-glutamyl)lysine isodipeptide bond.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'The presence of such bonds thus affords an explanation for the extraordinary insolubility of loricrin by cross-linking to the cell envelope and can also explain the low steady-state levels of monomeric loricrin in cytoskeletal extracts of epidermis.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'The presence of such bonds thus affords an explanation for the extraordinary insolubility of loricrin by cross-linking to the cell envelope and can also explain the low steady-state levels of monomeric loricrin in cytoskeletal extracts of epidermis.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.', answer the user's query. |
What is the biomedical concept corresponding to 'loricrin'? | [
"loricrin (homo sapiens)",
"loricrin cornified envelope precursor protein (homo sapiens)"
] | [
"loricrin-like (homo sapiens)",
"loricrin (bos taurus)",
"loricrin (xenopus tropicalis)",
"loricrin (mus musculus)"
] | Given the context 'We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.', answer the user's query. |
What is the biomedical concept corresponding to 'cocaine- and antidepressant-sensitive human noradrenaline transporter'? | [
"net (homo sapiens) (solute carrier family 6 member 2 (homo sapiens))",
"net1 (homo sapiens) (solute carrier family 6 member 2 (homo sapiens))",
"slc6a2 (homo sapiens)",
"nat1 (homo sapiens) (solute carrier family 6 member 2 (homo sapiens))"
] | [
"net1 (homo sapiens) (solute carrier family 6 member 5 (homo sapiens))",
"slc6a10 (homo sapiens)",
"nact (homo sapiens) (solute carrier family 13 member 2 (homo sapiens))",
"solute carrier family 1 member 2 (homo sapiens)"
] | Given the context 'Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
', answer the user's query. |
What is the biomedical concept corresponding to 'noradrenaline transporter'? | [
"net (homo sapiens) (solute carrier family 6 member 2 (homo sapiens))",
"slc6a2 (homo sapiens)"
] | [
"slc6a2 (rattus norvegicus)",
"slc6a1 (rattus norvegicus)",
"slc6a3 (rattus norvegicus)",
"solute carrier family 1 member 2 (rattus norvegicus)"
] | Given the context 'We have isolated a complementary DNA clone encoding a human noradrenaline transporter.', answer the user's query. |
What is the biomedical concept corresponding to 'ypt1'? | [
"ypt1 (saccharomyces cerevisiae s288c)",
"rab family gtpase ypt1 (saccharomyces cerevisiae s288c)"
] | [
"ypt1 (homo sapiens)",
"ypt11 (saccharomyces cerevisiae s288c)",
"ypt1 (candida albicans sc5314)",
"ypt6 (saccharomyces cerevisiae s288c)"
] | Given the context 'A set of 11 clones encoding putative GTP binding proteins highly homologous to the yeast YPT1/SEC4 gene products have been isolated from an MDCK cell cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'sec4'? | [
"sec4 (saccharomyces cerevisiae s288c)",
"rab family gtpase sec4 (saccharomyces cerevisiae s288c)"
] | [
"sec4 (candida albicans sc5314)",
"sec4l (homo sapiens)",
"sec24 (saccharomyces cerevisiae s288c)",
"exocyst complex component 4 (homo sapiens)"
] | Given the context 'A set of 11 clones encoding putative GTP binding proteins highly homologous to the yeast YPT1/SEC4 gene products have been isolated from an MDCK cell cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'rab2'? | [
"rab2 (homo sapiens)",
"rab2a, member ras oncogene family (homo sapiens)",
"rab2a (homo sapiens)"
] | [
"rab2 (drosophila melanogaster)",
"rab, member of ras oncogene family like 2a (homo sapiens)",
"rab2b, member ras oncogene family (homo sapiens)",
"rab, member of ras oncogene family like 2b (homo sapiens)"
] | Given the context 'One, the MDCK homolog of rab2, is associated with a structure having the characteristics of an intermediate compartment between the endoplasmic reticulum and the Golgi apparatus.', answer the user's query. |
What is the biomedical concept corresponding to 'rab5'? | [
"rab5 (homo sapiens)",
"rab5a (homo sapiens)",
"rab5a, member ras oncogene family (homo sapiens)"
] | [
"rab (drosophila melanogaster) (rab5 (drosophila melanogaster))",
"rab5c, member ras oncogene family (homo sapiens)",
"rab5c (homo sapiens)",
"rab5l (homo sapiens)"
] | Given the context 'The second, rab5, is located at the cytoplasmic surface of the plasma membrane and on early endosomes, while the third, rab7, is found on late endosomes.', answer the user's query. |
What is the biomedical concept corresponding to 'rab7'? | [
"rab7 (homo sapiens) (rab7a, member ras oncogene family (homo sapiens))",
"rab7a (homo sapiens)",
"rab7a, member ras oncogene family (homo sapiens)"
] | [
"rab7 (homo sapiens) (rab7b, member ras oncogene family (homo sapiens))",
"rab7b, member ras oncogene family (homo sapiens)",
"rab-7 (drosophila melanogaster)",
"rab7b (homo sapiens)"
] | Given the context 'The second, rab5, is located at the cytoplasmic surface of the plasma membrane and on early endosomes, while the third, rab7, is found on late endosomes.', answer the user's query. |
What is the biomedical concept corresponding to 'ypt1'? | [
"ypt1 (saccharomyces cerevisiae s288c)",
"rab family gtpase ypt1 (saccharomyces cerevisiae s288c)"
] | [
"ypt1 (homo sapiens)",
"ypt11 (saccharomyces cerevisiae s288c)",
"ypt1 (candida albicans sc5314)",
"ypt6 (saccharomyces cerevisiae s288c)"
] | Given the context 'These findings provide evidence that members of the YPT1/SEC4 subfamily of GTP binding proteins are localized to specific exocytic and endocytic subcompartments in mammalian cells.', answer the user's query. |
What is the biomedical concept corresponding to 'sec4'? | [
"sec4 (saccharomyces cerevisiae s288c)",
"rab family gtpase sec4 (saccharomyces cerevisiae s288c)"
] | [
"sec4 (candida albicans sc5314)",
"sec4l (homo sapiens)",
"sec24 (saccharomyces cerevisiae s288c)",
"exocyst complex component 4 (homo sapiens)"
] | Given the context 'These findings provide evidence that members of the YPT1/SEC4 subfamily of GTP binding proteins are localized to specific exocytic and endocytic subcompartments in mammalian cells.', answer the user's query. |
What is the biomedical concept corresponding to 'kdel receptor'? | [
"kdelr1 (homo sapiens)",
"kdel endoplasmic reticulum protein retention receptor 1 (homo sapiens)"
] | [
"kdel receptor (drosophila melanogaster)",
"kdelr (drosophila melanogaster)",
"kdelr (xenopus tropicalis)",
"kdelr3 (homo sapiens)"
] | Given the context 'In contrast, Vaux et al. suggest that the mammalian KDEL receptor is a 72K glycoprotein that they detected using an anti-idiotypic antibody approach.', answer the user's query. |
What is the biomedical concept corresponding to 'erd2'? | [
"erd2 (homo sapiens)",
"erd2.1 (homo sapiens)"
] | [
"erd2.2 (homo sapiens)",
"erda2 (homo sapiens)",
"erdj2 (homo sapiens)",
"kdel endoplasmic reticulum protein retention receptor 2 (homo sapiens)"
] | Given the context 'We report here that human cells express a protein similar in sequence, size and properties to the ERD2 product, and propose that this protein is the human KDEL receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'kdel receptor'? | [
"kdelr1 (homo sapiens)",
"kdel endoplasmic reticulum protein retention receptor 1 (homo sapiens)"
] | [
"kdel receptor (drosophila melanogaster)",
"kdelr (drosophila melanogaster)",
"kdelr (xenopus tropicalis)",
"kdelr3 (homo sapiens)"
] | Given the context 'We report here that human cells express a protein similar in sequence, size and properties to the ERD2 product, and propose that this protein is the human KDEL receptor.', answer the user's query. |
What is the biomedical concept corresponding to 'stem cell factor'? | [
"kit ligand (homo sapiens)",
"scf (homo sapiens)",
"sf (homo sapiens) (kit ligand (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"csf-1 (homo sapiens)",
"il-7 (homo sapiens) (interleukin 7 (homo sapiens))",
"csf1 (homo sapiens)"
] | Given the context 'Primary structure and functional expression of rat and human stem cell factor DNAs.
', answer the user's query. |
What is the biomedical concept corresponding to 'scf'? | [
"scf (homo sapiens)",
"kit ligand (homo sapiens)",
"sf (homo sapiens) (kit ligand (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"csf-1 (homo sapiens)",
"csf1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)"
] | Given the context 'Using probes based on the rat sequence, partial and full-length cDNA and genomic clones of human SCF have been isolated.', answer the user's query. |
What is the biomedical concept corresponding to 'scf'? | [
"scf (homo sapiens)",
"kit ligand (homo sapiens)",
"sf (homo sapiens) (kit ligand (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"csf-1 (homo sapiens)",
"csf1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)"
] | Given the context 'SCF is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow cultures.', answer the user's query. |
What is the biomedical concept corresponding to 'scf'? | [
"scf (homo sapiens)",
"kit ligand (homo sapiens)",
"sf (homo sapiens) (kit ligand (homo sapiens))"
] | [
"colony stimulating factor 1 (homo sapiens)",
"csf-1 (homo sapiens)",
"csf1 (homo sapiens)",
"colony stimulating factor 3 (homo sapiens)"
] | Given the context 'SCF exhibits potent synergistic activities in conjunction with colony-stimulating factors, resulting in increased colony numbers and colony size.', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'Autoantibodies to a novel nuclear Ag, Sp100, have recently been described that recognize a nuclear protein with an apparent molecular mass of 95 to 100 kDa and a dot-like distribution within cell nuclei.', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'By immunoscreening of a lambda gt11 cDNA expression library derived from HeLa cells with an anti-Sp100 autoimmune serum a 0.7-kb cDNA (Sp26) coding for a fragment of Sp100 was isolated.', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'By immunoscreening of a lambda gt11 cDNA expression library derived from HeLa cells with an anti-Sp100 autoimmune serum a 0.7-kb cDNA (Sp26) coding for a fragment of Sp100 was isolated.', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'Expression of this cDNA and use of the recombinant protein in ELISA revealed that the fragment carries major Sp100 autoepitopes and that anti-Sp100 autoantibodies predominantly occur in patients suffering from primary biliary cirrhosis (50/184).', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'Expression of this cDNA and use of the recombinant protein in ELISA revealed that the fragment carries major Sp100 autoepitopes and that anti-Sp100 autoantibodies predominantly occur in patients suffering from primary biliary cirrhosis (50/184).', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'The Sp100 autoantigen expressed in vitro from this cDNA and authenticated by a capture immunoblot assay, comigrated in SDS-PAGE with the authentic HeLa autoantigen of 95 to 100 kDa and thus showed an aberrant electrophoretic mobility.', answer the user's query. |
What is the biomedical concept corresponding to 'sp100'? | [
"sp100 (homo sapiens)",
"sp100 nuclear antigen (homo sapiens)"
] | [
"sp100 (sus scrofa)",
"sp100 (mus musculus)",
"sp100 (bos taurus)",
"nuclear antigen sp100 (mus musculus)"
] | Given the context 'Computer based protein sequence analysis of the Sp100 autoantigen revealed regions of striking sequence similarities to the alpha 1 and alpha 2 domains of various human and non-human MHC class I Ag and to several transacting transcriptional regulatory proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'fc alpha r'? | [
"fcalphar (homo sapiens)",
"fc alpha receptor (homo sapiens)",
"fcalphari (homo sapiens)",
"fcar (homo sapiens)"
] | [
"fcamr (homo sapiens)",
"fcgr1a (homo sapiens)",
"fcgammariia (homo sapiens)",
"fcriiia (homo sapiens)"
] | Given the context 'Although cell surface receptors for the Fc region of IgA (Fc alpha R) have been implicated in a variety of immune effector mechanisms, the molecular features of Fc alpha R remain only marginally characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'fc alpha r'? | [
"fcalphar (homo sapiens)",
"fc alpha receptor (homo sapiens)",
"fcalphari (homo sapiens)",
"fcar (homo sapiens)"
] | [
"fcamr (homo sapiens)",
"fcgr1a (homo sapiens)",
"fcgammariia (homo sapiens)",
"fcriiia (homo sapiens)"
] | Given the context 'Although cell surface receptors for the Fc region of IgA (Fc alpha R) have been implicated in a variety of immune effector mechanisms, the molecular features of Fc alpha R remain only marginally characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'fc alpha r'? | [
"fcalphar (homo sapiens)",
"fc alpha receptor (homo sapiens)",
"fcalphari (homo sapiens)",
"fcar (homo sapiens)"
] | [
"fcamr (homo sapiens)",
"fcgr1a (homo sapiens)",
"fcgammariia (homo sapiens)",
"fcriiia (homo sapiens)"
] | Given the context 'Databank searches indicate that the human myeloid cell Fc alpha R sequence is unique, is a member of the immunoglobulin gene superfamily, and is related to Fc receptors for IgG (Fc gamma RI, II, and III) and IgE (Fc epsilon RI).', answer the user's query. |
What is the biomedical concept corresponding to 'fc epsilon ri'? | [
"fc epsilon receptor ia (homo sapiens)"
] | [
"fcgammariia (homo sapiens)",
"fc epsilon receptor ig (homo sapiens)",
"fc epsilon receptor ii (homo sapiens)",
"fcalphari (homo sapiens)"
] | Given the context 'Databank searches indicate that the human myeloid cell Fc alpha R sequence is unique, is a member of the immunoglobulin gene superfamily, and is related to Fc receptors for IgG (Fc gamma RI, II, and III) and IgE (Fc epsilon RI).', answer the user's query. |
What is the biomedical concept corresponding to 'ferrochelatase'? | [
"ferrochelatase (homo sapiens)"
] | [
"ferrochelatase (gallus gallus)",
"ferrochelatase (bos taurus)",
"ferrochelatase (xenopus tropicalis)",
"ferrochelatase (drosophila melanogaster)"
] | Given the context 'Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase.
', answer the user's query. |
What is the biomedical concept corresponding to 'ferrochelatase'? | [
"ferrochelatase (homo sapiens)"
] | [
"ferrochelatase (gallus gallus)",
"ferrochelatase (bos taurus)",
"ferrochelatase (xenopus tropicalis)",
"ferrochelatase (drosophila melanogaster)"
] | Given the context 'The cDNA encoding human ferrochelatase', answer the user's query. |
What is the biomedical concept corresponding to 'ferrochelatase'? | [
"ferrochelatase (homo sapiens)"
] | [
"ferrochelatase (gallus gallus)",
"ferrochelatase (bos taurus)",
"ferrochelatase (xenopus tropicalis)",
"ferrochelatase (drosophila melanogaster)"
] | Given the context 'Northern blot analysis showed two mRNAs of about 2500 and 1600 bp for ferrochelatase in K562 and HepG2 cells.', answer the user's query. |
What is the biomedical concept corresponding to 'ferrochelatase'? | [
"ferrochelatase (homo sapiens)"
] | [
"ferrochelatase (gallus gallus)",
"ferrochelatase (bos taurus)",
"ferrochelatase (xenopus tropicalis)",
"ferrochelatase (drosophila melanogaster)"
] | Given the context 'As full-length cDNA for human ferrochelatase is now available, molecular lesions related to erythropoietic protoporphyria can be characterized.', answer the user's query. |
What is the biomedical concept corresponding to 'pancreatic cholesterol esterase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"lipase e, hormone sensitive type (homo sapiens)",
"carboxyl ester lipase (sus scrofa)",
"lipase e, hormone sensitive type (oryctolagus cuniculus)",
"lipase e, hormone sensitive type (sus scrofa)"
] | Given the context 'Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.
', answer the user's query. |
What is the biomedical concept corresponding to 'bile salt-stimulated milk lipase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"carboxyl ester lipase (bos taurus)",
"lipase c, hepatic type (bos taurus)",
"carboxyl ester lipase (sus scrofa)",
"lipase e, hormone sensitive type (bos taurus)"
] | Given the context 'Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.
', answer the user's query. |
What is the biomedical concept corresponding to 'milk lipase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"carboxyl ester lipase (gallus gallus)",
"lipase, gastric (mus musculus)",
"pancreatic lipase (bos taurus)",
"lipase h (gallus gallus)"
] | Given the context 'Nucleotide sequencing of the cDNA showed that the human milk lipase mRNA encodes a 748-residue protein, including a 23-residue signal peptide.', answer the user's query. |
What is the biomedical concept corresponding to 'milk lipase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"carboxyl ester lipase (gallus gallus)",
"lipase, gastric (mus musculus)",
"pancreatic lipase (bos taurus)",
"lipase h (gallus gallus)"
] | Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'milk lipase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"carboxyl ester lipase (gallus gallus)",
"lipase, gastric (mus musculus)",
"pancreatic lipase (bos taurus)",
"lipase h (gallus gallus)"
] | Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'cholesterol esterase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"cocaine esterase (oryctolagus cuniculus) (loc127491327 (oryctolagus cuniculus))",
"lipase e, hormone sensitive type (homo sapiens)",
"carboxyl ester lipase (oryctolagus cuniculus)",
"neutral cholesterol ester hydrolase 1 (homo sapiens)"
] | Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', answer the user's query. |
What is the biomedical concept corresponding to 'pancreatic cholesterol esterase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"lipase e, hormone sensitive type (homo sapiens)",
"carboxyl ester lipase (sus scrofa)",
"lipase e, hormone sensitive type (oryctolagus cuniculus)",
"lipase e, hormone sensitive type (sus scrofa)"
] | Given the context 'This conclusion was confirmed by isolation and sequencing of the cDNA for human pancreatic cholesterol esterase.', answer the user's query. |
What is the biomedical concept corresponding to 'cholesterol esterase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"cocaine esterase (oryctolagus cuniculus) (loc127491327 (oryctolagus cuniculus))",
"lipase e, hormone sensitive type (homo sapiens)",
"carboxyl ester lipase (oryctolagus cuniculus)",
"neutral cholesterol ester hydrolase 1 (homo sapiens)"
] | Given the context 'Analysis of the sequence for the human cholesterol esterase/milk lipase revealed similarities to other serine esterases in three distinct regions of the protein.', answer the user's query. |
What is the biomedical concept corresponding to 'milk lipase'? | [
"carboxyl ester lipase (homo sapiens)"
] | [
"carboxyl ester lipase (gallus gallus)",
"lipase, gastric (mus musculus)",
"pancreatic lipase (bos taurus)",
"lipase h (gallus gallus)"
] | Given the context 'Analysis of the sequence for the human cholesterol esterase/milk lipase revealed similarities to other serine esterases in three distinct regions of the protein.', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta subunit'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)",
"bckdh e1-beta (homo sapiens)"
] | [
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"e1betad (homo sapiens)",
"pdhe1b (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)"
] | Given the context 'Complete primary structure of the E1 beta subunit of human branched chain alpha-ketoacid dehydrogenase complex deduced from the nucleotide sequence and a gene analysis of patients with this disease.
', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta subunit'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)",
"bckdh e1-beta (homo sapiens)"
] | [
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"e1betad (homo sapiens)",
"pdhe1b (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)"
] | Given the context 'A defect in the E1 beta subunit of the branched chain alpha-ketoacid dehydrogenase (BCKDH) complex is one cause of maple syrup urine disease (MSUD).', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta subunit'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)",
"bckdh e1-beta (homo sapiens)"
] | [
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"e1betad (homo sapiens)",
"pdhe1b (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)"
] | Given the context 'In an attempt to elucidate the molecular basis of MSUD, we isolated and characterized a 1.35 kbp cDNA clone encoding the entire precursor of the E1 beta subunit of BCKDH complex from a human placental cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"bckdh e1-beta (homo sapiens)",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)"
] | [
"e1betad (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)",
"pdhe1b (homo sapiens)"
] | Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta subunit'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)",
"bckdh e1-beta (homo sapiens)"
] | [
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"e1betad (homo sapiens)",
"pdhe1b (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)"
] | Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', answer the user's query. |
What is the biomedical concept corresponding to 'e1 beta'? | [
"e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens))",
"bckdh e1-beta (homo sapiens)",
"branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)"
] | [
"e1betad (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (homo sapiens)",
"pyruvate dehydrogenase e1 subunit beta (rattus norvegicus)",
"pdhe1b (homo sapiens)"
] | Given the context 'Genomic DNA from lymphoblastoid cell lines derived from normal and five MSUD patients, in whom E1 beta was not detected by immunoblot analysis, gave the same restriction maps on Southern blot analysis.', answer the user's query. |
What is the biomedical concept corresponding to 'k7'? | [
"k7 (homo sapiens) (keratin 7 (homo sapiens))",
"krt7 (homo sapiens)"
] | [
"k7 (mus musculus) (keratin 7 (mus musculus))",
"k6 (mus musculus)",
"k77 (mus musculus)",
"k8 (mus musculus)"
] | Given the context 'A cloned cDNA encoding keratin K7 (55 kD) was identified by positive hybrid selection.', answer the user's query. |
What is the biomedical concept corresponding to 'k7'? | [
"k7 (homo sapiens) (keratin 7 (homo sapiens))",
"krt7 (homo sapiens)"
] | [
"k7 (mus musculus) (keratin 7 (mus musculus))",
"k6 (mus musculus)",
"k77 (mus musculus)",
"k8 (mus musculus)"
] | Given the context 'Southern Blot analysis indicated that this sequence is represented only once in the human genome, and Northern Blot analysis demonstrated that the gene encoding K7 is expressed in abundance in cultured bronchial and mesothelial cells, but only weakly in cultured epidermal cells and not at all in liver, colon, or exocervical tissue.', answer the user's query. |
What is the biomedical concept corresponding to 'melanoma-associated antigen p97'? | [
"map97 (homo sapiens)"
] | [
"ct97 (homo sapiens)",
"cfap97 (homo sapiens)",
"cilia and flagella associated protein 97 (homo sapiens)",
"hspc97 (homo sapiens)"
] | Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'melanotransferrin'? | [
"melanotransferrin (homo sapiens)",
"mtf (homo sapiens) (melanotransferrin (homo sapiens))",
"mtf1 (homo sapiens) (melanotransferrin (homo sapiens))"
] | [
"melanotransferrin (mus musculus)",
"melanotransferrin (xenopus tropicalis)",
"melanotransferrin (bos taurus)",
"melanotransferrin (gallus gallus)"
] | Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'To determine the structure of this tumor-associated antigen and to identify its functional domains, we have purified and cloned p97 mRNA and determined its nucleotide sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'The mRNA encodes a 738-residue precursor, which contains the previously determined N-terminal amino acid sequence of p97.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'After removal of a 19-residue signal peptide, the mature p97 molecule comprises extracellular domains of 342 and 352 residues and a C-terminal 25-residue stretch of predominantly uncharged and hydrophobic amino acids, which we believe acts as a membrane anchor.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'Protease digestion studies show that the three major antigenic determinants of p97 are present on the N-terminal domain.', answer the user's query. |
What is the biomedical concept corresponding to 'transferrin'? | [
"transferrin (homo sapiens)",
"tf (homo sapiens) (transferrin (homo sapiens))"
] | [
"transferrin receptor (homo sapiens)",
"transferrin receptor (gallus gallus)",
"transferrin (ovotransferrin) (gallus gallus)",
"tfr (homo sapiens)"
] | Given the context 'The domains are strikingly homologous to each other (46% amino acid sequence homology) and to the corresponding domains of human serum transferrin (39% homology).', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'Conservation of disulfide bridges and of amino acids thought to compose the iron binding pockets suggests that p97 is also related to transferrin in tertiary structure and function.', answer the user's query. |
What is the biomedical concept corresponding to 'transferrin'? | [
"transferrin (homo sapiens)",
"tf (homo sapiens) (transferrin (homo sapiens))"
] | [
"transferrin receptor (homo sapiens)",
"transferrin receptor (gallus gallus)",
"transferrin (ovotransferrin) (gallus gallus)",
"tfr (homo sapiens)"
] | Given the context 'Conservation of disulfide bridges and of amino acids thought to compose the iron binding pockets suggests that p97 is also related to transferrin in tertiary structure and function.', answer the user's query. |
What is the biomedical concept corresponding to 'p97'? | [
"map97 (homo sapiens)"
] | [
"hspc97 (homo sapiens)",
"p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens))",
"p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster))",
"ec97 (homo sapiens)"
] | Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'melanotransferrin'? | [
"melanotransferrin (homo sapiens)",
"mtf (homo sapiens) (melanotransferrin (homo sapiens))",
"mtf1 (homo sapiens) (melanotransferrin (homo sapiens))"
] | [
"melanotransferrin (mus musculus)",
"melanotransferrin (xenopus tropicalis)",
"melanotransferrin (bos taurus)",
"melanotransferrin (gallus gallus)"
] | Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'serotransferrin'? | [
"transferrin (homo sapiens)",
"tf (homo sapiens) (transferrin (homo sapiens))"
] | [
"serotransferrin (glycine max)",
"hemiferrin, transferrin-like protein (rattus norvegicus)",
"transferrin receptor (homo sapiens)",
"transferrin (sus scrofa)"
] | Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'lactotransferrin'? | [
"lactotransferrin (homo sapiens)"
] | [
"lactotransferrin (bos taurus)",
"lactotransferrin (rattus norvegicus)",
"lactoferrin (xenopus tropicalis)",
"lactoferrin (xenopus laevis) (transferrin l homeolog (xenopus laevis))"
] | Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'transferrin'? | [
"transferrin (homo sapiens)",
"tf (homo sapiens) (transferrin (homo sapiens))"
] | [
"transferrin receptor (homo sapiens)",
"transferrin receptor (gallus gallus)",
"transferrin (ovotransferrin) (gallus gallus)",
"tfr (homo sapiens)"
] | Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', answer the user's query. |
What is the biomedical concept corresponding to 'calcineurin b'? | [
"cnb (homo sapiens)"
] | [
"cnb (drosophila melanogaster) (calcineurin b (drosophila melanogaster))",
"pp2cbeta (homo sapiens)",
"ppp3cb (homo sapiens)",
"prkcbb (xenopus tropicalis)"
] | Given the context 'Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.
', answer the user's query. |
What is the biomedical concept corresponding to 'ca2+-binding subunit of calcineurin'? | [
"cnb (homo sapiens)",
"calnb1 (homo sapiens)",
"cnb1 (homo sapiens)"
] | [
"calnb (homo sapiens)",
"caln1 (homo sapiens)",
"calb (homo sapiens)",
"cngb1 (xenopus tropicalis)"
] | Given the context 'We have identified and cloned human cDNA for the Ca2+-binding subunit of calcineurin, the brain isozyme of the Ca2+/calmodulin-stimulated protein phosphatase.', answer the user's query. |
What is the biomedical concept corresponding to 'calcineurin b'? | [
"cnb (homo sapiens)"
] | [
"cnb (drosophila melanogaster) (calcineurin b (drosophila melanogaster))",
"pp2cbeta (homo sapiens)",
"ppp3cb (homo sapiens)",
"prkcbb (xenopus tropicalis)"
] | Given the context 'The deduced sequence of the human protein differs from bovine brain calcineurin B by an additional valine at the carboxyl terminus and substitution of Met-11 and Ser-153 by cysteine.', answer the user's query. |
What is the biomedical concept corresponding to 'calcineurin b'? | [
"cnb (homo sapiens)"
] | [
"cnb (drosophila melanogaster) (calcineurin b (drosophila melanogaster))",
"pp2cbeta (homo sapiens)",
"ppp3cb (homo sapiens)",
"prkcbb (xenopus tropicalis)"
] | Given the context 'As was observed with protein levels, mRNA abundance in brain is 20-60 times that found in other tissues with the exception of HeLa cells which, like brain, contain abundant calcineurin B mRNA.', answer the user's query. |
What is the biomedical concept corresponding to 'serine dehydratase'? | [
"serine dehydratase (homo sapiens)",
"sds (homo sapiens) (serine dehydratase (homo sapiens))"
] | [
"serine dehydratase (bos taurus)",
"serine dehydratase (sus scrofa)",
"serine dehydratase (xenopus tropicalis)",
"serine dehydratase like (homo sapiens)"
] | Given the context 'Human liver serine dehydratase.', answer the user's query. |
What is the biomedical concept corresponding to 'serine dehydratase'? | [
"serine dehydratase (homo sapiens)",
"sds (homo sapiens) (serine dehydratase (homo sapiens))"
] | [
"serine dehydratase (bos taurus)",
"serine dehydratase (sus scrofa)",
"serine dehydratase (xenopus tropicalis)",
"serine dehydratase like (homo sapiens)"
] | Given the context 'These results suggest that the human serine dehydratase is structurally cognate with the rat enzyme.', answer the user's query. |
What is the biomedical concept corresponding to 'rac1'? | [
"rac1 (homo sapiens) (rac family small gtpase 1 (homo sapiens))",
"p21-rac1 (homo sapiens)",
"rac family small gtpase 1 (homo sapiens)",
"rac-1 (homo sapiens)"
] | [
"rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))"
] | Given the context 'rac1 and rac2 cDNA clones were isolated from a differentiated HL-60 library and encode proteins that are 92% homologous and share 58% and 26-30% amino acid homology with human rhos and ras, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'rac2'? | [
"rac2 (homo sapiens)",
"rac family small gtpase 2 (homo sapiens)",
"p21-rac2 (homo sapiens)"
] | [
"rac (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac-beta (homo sapiens)"
] | Given the context 'rac1 and rac2 cDNA clones were isolated from a differentiated HL-60 library and encode proteins that are 92% homologous and share 58% and 26-30% amino acid homology with human rhos and ras, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'rac1'? | [
"rac1 (homo sapiens) (rac family small gtpase 1 (homo sapiens))",
"p21-rac1 (homo sapiens)",
"rac family small gtpase 1 (homo sapiens)",
"rac-1 (homo sapiens)"
] | [
"rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))"
] | Given the context 'Nucleotide sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with molecular masses of 21,450 and 21,429 daltons, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'rac2'? | [
"rac2 (homo sapiens)",
"rac family small gtpase 2 (homo sapiens)",
"p21-rac2 (homo sapiens)"
] | [
"rac (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac-beta (homo sapiens)"
] | Given the context 'Nucleotide sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with molecular masses of 21,450 and 21,429 daltons, respectively.', answer the user's query. |
What is the biomedical concept corresponding to 'rac1'? | [
"rac1 (homo sapiens) (rac family small gtpase 1 (homo sapiens))",
"p21-rac1 (homo sapiens)",
"rac family small gtpase 1 (homo sapiens)",
"rac-1 (homo sapiens)"
] | [
"rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))"
] | Given the context 'rac1 and rac2 possess four of the five conserved functional domains in ras associated with binding and hydrolysis of guanine nucleotides.', answer the user's query. |
What is the biomedical concept corresponding to 'rac2'? | [
"rac2 (homo sapiens)",
"rac family small gtpase 2 (homo sapiens)",
"p21-rac2 (homo sapiens)"
] | [
"rac (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac-beta (homo sapiens)"
] | Given the context 'rac1 and rac2 possess four of the five conserved functional domains in ras associated with binding and hydrolysis of guanine nucleotides.', answer the user's query. |
What is the biomedical concept corresponding to 'rac2'? | [
"rac2 (homo sapiens)",
"rac family small gtpase 2 (homo sapiens)",
"p21-rac2 (homo sapiens)"
] | [
"rac (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))",
"rac-beta (homo sapiens)"
] | Given the context 'The rac transcripts, particularly rac2, display relative myeloid tissue selectivity.', answer the user's query. |
What is the biomedical concept corresponding to 'rac1'? | [
"rac1 (homo sapiens) (rac family small gtpase 1 (homo sapiens))",
"p21-rac1 (homo sapiens)",
"rac family small gtpase 1 (homo sapiens)",
"rac-1 (homo sapiens)"
] | [
"rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster))",
"rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac (drosophila melanogaster) (rac1 (drosophila melanogaster))",
"rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster))"
] | Given the context 'Both rac1 transcripts (2.4 and 1.1 kilobases (kb] increase when HL-60 cells differentiate to neutrophil-like morphology.', answer the user's query. |
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