query string | positive list | negative list | system string |
|---|---|---|---|
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'A approximately 35-kDa polypeptide with a unique NH2-terminal sequence has been isolated from bovine lung and found to be present on the surface of endothelial cells where it mediates the binding of AGEs (receptor for advanced glycosylation end product or RAGE).', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Using an oligonucleotide probe based on the amino-terminal sequence of RAGE, an apparently full-length cDNA of 1.5 kilobases was isolated from a bovine lung cDNA library.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'A partial clone encoding the human counterpart of RAGE, isolated from a human lung library, was found to be approximately 90% homologous to the bovine molecule.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', answer the user's query. |
What is the biomedical concept corresponding to 'muc 18'? | [
"muc18 (homo sapiens)"
] | [
"ceacam18 (homo sapiens)",
"mucin-18 (gallus gallus)",
"cea cell adhesion molecule 18 (homo sapiens)",
"k18 (homo sapiens)"
] | Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', answer the user's query. |
What is the biomedical concept corresponding to 'ncam'? | [
"ncam (homo sapiens)",
"ncam1 (homo sapiens)"
] | [
"ncam (neural cell adhesion molecule) homolog (caenorhabditis elegans)",
"ncam-1 (mus musculus)",
"ncam (mus musculus)",
"ncam-l1 (homo sapiens)"
] | Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', answer the user's query. |
What is the biomedical concept corresponding to 'cd20'? | [
"cd20 (homo sapiens) (membrane spanning 4-domains a1 (homo sapiens))"
] | [
"cd20l (homo sapiens)",
"cd20 (bos taurus)",
"cd20l1 (homo sapiens)",
"cd20l2 (homo sapiens)"
] | Given the context 'Based on computer analysis of the amino acid sequence of RAGE and comparison with databases, RAGE is a new member of the immunoglobulin superfamily of cell surface molecules and shares significant homology with MUC 18, NCAM, and the cytoplasmic domain of CD20.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Expression of the RAGE cDNA in 293 cells allowed them to bind 125I-AGE-albumin in a saturable and dose-dependent manner (Kd approximately 100 nM), blocked by antibody to RAGE.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'Western blots of 293 cells transfected with RAGE cDNA probed with anti-RAGE IgG demonstrated expression of immunoreactive protein compared to its absence in mock-transfected cells.', answer the user's query. |
What is the biomedical concept corresponding to 'rage'? | [
"rage (homo sapiens) (advanced glycosylation end-product specific receptor (homo sapiens))"
] | [
"rage-1 (homo sapiens)",
"rage1 (homo sapiens)",
"rage (gallus gallus)",
"ragef (homo sapiens)"
] | Given the context 'These results suggest that RAGE functions as a cell surface receptor for AGEs, which could potentially mediate cellular effects of this class of glycosylated proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'cd59'? | [
"cd59 molecule (cd59 blood group) (homo sapiens)",
"cd59 (homo sapiens)"
] | [
"cd5 molecule (homo sapiens)",
"cd55 (homo sapiens)",
"cd5 (homo sapiens)",
"cd52 molecule (homo sapiens)"
] | Given the context 'Structure of the CD59-encoding gene: further evidence of a relationship to murine lymphocyte antigen Ly-6 protein.
', answer the user's query. |
What is the biomedical concept corresponding to 'cd59'? | [
"cd59 molecule (cd59 blood group) (homo sapiens)",
"cd59 (homo sapiens)"
] | [
"cd5 molecule (homo sapiens)",
"cd55 (homo sapiens)",
"cd5 (homo sapiens)",
"cd52 molecule (homo sapiens)"
] | Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', answer the user's query. |
What is the biomedical concept corresponding to 'membrane inhibitor of reactive lysis'? | [
"cd59 molecule (cd59 blood group) (homo sapiens)"
] | [
"bmp and activin membrane bound inhibitor (homo sapiens)",
"metalloproteinase inhibitor 1-like (bos taurus)",
"migration and invasion inhibitory protein (bos taurus)",
"migration and invasion inhibitory protein (homo sapiens)"
] | Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', answer the user's query. |
What is the biomedical concept corresponding to 'mirl'? | [
"mirl (homo sapiens)"
] | [
"mir (drosophila melanogaster) (miranda (drosophila melanogaster))",
"miro (drosophila melanogaster) (mitochondrial rho (drosophila melanogaster))",
"mira (drosophila melanogaster)",
"mical-like (drosophila melanogaster)"
] | Given the context 'The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of the polymeric C9 complex of complement and that is deficient on the abnormal hematopoietic cells of patients with paroxysmal nocturnal hemoglobinuria, consists of four exons spanning 20 kilobases.', answer the user's query. |
What is the biomedical concept corresponding to 'cd59'? | [
"cd59 molecule (cd59 blood group) (homo sapiens)",
"cd59 (homo sapiens)"
] | [
"cd5 molecule (homo sapiens)",
"cd55 (homo sapiens)",
"cd5 (homo sapiens)",
"cd52 molecule (homo sapiens)"
] | Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', answer the user's query. |
What is the biomedical concept corresponding to 'cd59'? | [
"cd59 molecule (cd59 blood group) (homo sapiens)",
"cd59 (homo sapiens)"
] | [
"cd5 molecule (homo sapiens)",
"cd55 (homo sapiens)",
"cd5 (homo sapiens)",
"cd52 molecule (homo sapiens)"
] | Given the context 'The structure of the CD59 gene is very similar to that encoding Ly-6, a murine glycoprotein with which CD59 has some structural similarity.', answer the user's query. |
What is the biomedical concept corresponding to 'urokinase plasminogen-activator receptor'? | [
"plasminogen activator, urokinase receptor (homo sapiens)",
"upar (homo sapiens)",
"urkr (homo sapiens)"
] | [
"plasminogen activator, urokinase receptor (sus scrofa)",
"plasminogen activator, urokinase receptor (mus musculus)",
"plasminogen activator, urokinase receptor (rattus norvegicus)",
"plasminogen activator, urokinase receptor (bos taurus)"
] | Given the context 'The striking similarity in gene structure is further evidence that the two proteins belong to a superfamily of proteins that may also include the urokinase plasminogen-activator receptor and a squid glycoprotein of unknown function.', answer the user's query. |
What is the biomedical concept corresponding to 'interleukin-1 receptor antagonist'? | [
"interleukin 1 receptor antagonist (homo sapiens)",
"il1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"il-1rn (homo sapiens)",
"il1rn (homo sapiens)"
] | [
"interleukin 1 receptor antagonist (rattus norvegicus)",
"interleukin 1 receptor antagonist (mus musculus)",
"interleukin 36 receptor antagonist (homo sapiens)",
"il1rp1 (homo sapiens)"
] | Given the context 'Cloning and chromosome mapping of the human interleukin-1 receptor antagonist gene.
', answer the user's query. |
What is the biomedical concept corresponding to 'interleukin-1 receptor antagonist'? | [
"interleukin 1 receptor antagonist (homo sapiens)",
"il1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"il-1rn (homo sapiens)",
"il1rn (homo sapiens)"
] | [
"interleukin 1 receptor antagonist (rattus norvegicus)",
"interleukin 1 receptor antagonist (mus musculus)",
"interleukin 36 receptor antagonist (homo sapiens)",
"il1rp1 (homo sapiens)"
] | Given the context 'By screening a human genomic library with an interleukin-1 receptor antagonist (IL-1ra) cDNA probe, we have isolated a 15 kb clone which contains the entire coding region of the gene as expressed in monocytes, and includes 6 kb of 5'-upstream sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1ra'? | [
"il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"interleukin 1 receptor antagonist (homo sapiens)",
"il1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"icil-1ra (homo sapiens)"
] | [
"il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens))",
"il-1racp (homo sapiens)",
"il-1rrp (homo sapiens)",
"il-1r-alpha (homo sapiens)"
] | Given the context 'By screening a human genomic library with an interleukin-1 receptor antagonist (IL-1ra) cDNA probe, we have isolated a 15 kb clone which contains the entire coding region of the gene as expressed in monocytes, and includes 6 kb of 5'-upstream sequence.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1ra'? | [
"il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"interleukin 1 receptor antagonist (homo sapiens)",
"il1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"icil-1ra (homo sapiens)"
] | [
"il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens))",
"il-1racp (homo sapiens)",
"il-1rrp (homo sapiens)",
"il-1r-alpha (homo sapiens)"
] | Given the context 'The gene contains four exons which code for the secreted form of the IL-1ra, however, our clone does not contain the alternative first exon used to generate an intracellular form of the protein as the protein as found in epithelial cells.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1ra'? | [
"il-1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"interleukin 1 receptor antagonist (homo sapiens)",
"il1ra (homo sapiens) (interleukin 1 receptor antagonist (homo sapiens))",
"icil-1ra (homo sapiens)"
] | [
"il-1ra (homo sapiens) (interleukin 6 receptor (homo sapiens))",
"il-1racp (homo sapiens)",
"il-1rrp (homo sapiens)",
"il-1r-alpha (homo sapiens)"
] | Given the context 'By in-situ fluorescence hybridization we have shown that the IL-1ra gene is found on the long arm of chromosome 2 and maps to 2q13-14.1.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1 alpha'? | [
"interleukin 1 alpha (homo sapiens)",
"il-1 alpha (homo sapiens)",
"il-1a (homo sapiens)",
"il1-alpha (homo sapiens)",
"il1a (homo sapiens)"
] | [
"interferon alpha 1 (homo sapiens)",
"il-1 (homo sapiens)",
"ifn1@ (homo sapiens)",
"il-1h1 (homo sapiens)"
] | Given the context 'Previous studies have revealed that IL-1 alpha, and IL-1 beta and both type I and type II forms of the IL-1 receptor all map close to this region of chromosome 2.', answer the user's query. |
What is the biomedical concept corresponding to 'il-1 beta'? | [
"interleukin 1 beta (homo sapiens)",
"il1-beta (homo sapiens)",
"il1beta (homo sapiens)",
"il1b (homo sapiens)",
"il-1 (homo sapiens)"
] | [
"interferon beta 1 (homo sapiens)",
"ifn-beta (homo sapiens)",
"interleukin 36 beta (homo sapiens)",
"ifnb1 (homo sapiens)"
] | Given the context 'Previous studies have revealed that IL-1 alpha, and IL-1 beta and both type I and type II forms of the IL-1 receptor all map close to this region of chromosome 2.', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', answer the user's query. |
What is the biomedical concept corresponding to 'eaoh'? | [
"eaoh (homo sapiens)",
"eoaha (homo sapiens)"
] | [
"oohe (homo sapiens)",
"eaa1 (homo sapiens)",
"eay (drosophila melanogaster) (eyes absent (drosophila melanogaster))",
"yhae (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', answer the user's query. |
What is the biomedical concept corresponding to 'early-onset ataxia with ocular motor apraxia and hypoalbuminemia'? | [
"eoaha (homo sapiens)",
"eaoh (homo sapiens)"
] | [
"episodic ataxia, type 7 (homo sapiens)",
"episodic ataxia, type 8 (homo sapiens)",
"aoeb166 (homo sapiens)",
"cogan-type congential oculomotor apraxia (homo sapiens)"
] | Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', answer the user's query. |
What is the biomedical concept corresponding to 'eaoh'? | [
"eaoh (homo sapiens)",
"eoaha (homo sapiens)"
] | [
"oohe (homo sapiens)",
"eaa1 (homo sapiens)",
"eay (drosophila melanogaster) (eyes absent (drosophila melanogaster))",
"yhae (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'Aprataxin, the causative protein for EAOH is a nuclear protein with a potential role as a DNA repair protein.
Early-onset ataxia with ocular motor apraxia and hypoalbuminemia (EAOH) is an autosomal recessive neurodegenerative disorder characterized by early-onset ataxia, ocular motor apraxia, and hypoalbuminemia.', answer the user's query. |
What is the biomedical concept corresponding to 'eaoh'? | [
"eaoh (homo sapiens)",
"eoaha (homo sapiens)"
] | [
"oohe (homo sapiens)",
"eaa1 (homo sapiens)",
"eay (drosophila melanogaster) (eyes absent (drosophila melanogaster))",
"yhae (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'Recently, the causative gene for EAOH, APTX, has been identified.', answer the user's query. |
What is the biomedical concept corresponding to 'aptx'? | [
"aptx (homo sapiens)"
] | [
"aptx (arabidopsis thaliana)",
"aptx (xenopus laevis)",
"aptx (xenopus tropicalis)",
"aptx (drosophila melanogaster)"
] | Given the context 'Recently, the causative gene for EAOH, APTX, has been identified.', answer the user's query. |
What is the biomedical concept corresponding to 'aptx'? | [
"aptx (homo sapiens)"
] | [
"aptx (arabidopsis thaliana)",
"aptx (xenopus laevis)",
"aptx (xenopus tropicalis)",
"aptx (drosophila melanogaster)"
] | Given the context 'Of the two splicing variants of APTX mRNA, the short and the long forms, long-form APTX mRNA was found to be the major isoform.', answer the user's query. |
What is the biomedical concept corresponding to 'aptx'? | [
"aptx (homo sapiens)"
] | [
"aptx (arabidopsis thaliana)",
"aptx (xenopus laevis)",
"aptx (xenopus tropicalis)",
"aptx (drosophila melanogaster)"
] | Given the context 'Of the two splicing variants of APTX mRNA, the short and the long forms, long-form APTX mRNA was found to be the major isoform.', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'Aprataxin is mainly located in the nucleus, and, furthermore, the first nuclear localization signal located near the amino terminus of the long-form aprataxin is essential for its nuclear localization.', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'Aprataxin is mainly located in the nucleus, and, furthermore, the first nuclear localization signal located near the amino terminus of the long-form aprataxin is essential for its nuclear localization.', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', answer the user's query. |
What is the biomedical concept corresponding to 'xrcc1'? | [
"xrcc1 (homo sapiens)",
"x-ray repair cross complementing 1 (homo sapiens)"
] | [
"xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis))",
"xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis))",
"xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis))",
... | Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', answer the user's query. |
What is the biomedical concept corresponding to 'x-ray repair cross-complementing group 1'? | [
"x-ray repair cross complementing 1 (homo sapiens)",
"xrcc1 (homo sapiens)"
] | [
"x-ray repair cross complementing 5 (homo sapiens)",
"x-ray repair cross complementing 6 (homo sapiens)",
"x-ray repair cross complementing 1 (oryctolagus cuniculus)",
"x-ray repair cross complementing 3 (homo sapiens)"
] | Given the context 'We found, based on the yeast two-hybrid and coimmunoprecipitation experiments, that the long-form but not the short-form aprataxin interacts with XRCC1 (x-ray repair cross-complementing group 1).', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', answer the user's query. |
What is the biomedical concept corresponding to 'polynucleotidekinase-3'-phosphatase'? | [
"polynucleotide kinase 3'-phosphatase (homo sapiens)",
"pnk (homo sapiens) (polynucleotide kinase 3'-phosphatase (homo sapiens))"
] | [
"polynucleotide kinase 3'-phosphatase (xenopus tropicalis)",
"polynucleotide kinase 3'-phosphatase (drosophila melanogaster)",
"polynucleotide kinase 3'-phosphatase (sus scrofa)",
"polynucleotide kinase 3'- phosphatase (mus musculus)"
] | Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', answer the user's query. |
What is the biomedical concept corresponding to 'xrcc1'? | [
"xrcc1 (homo sapiens)",
"x-ray repair cross complementing 1 (homo sapiens)"
] | [
"xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis))",
"xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis))",
"xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis))",
... | Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', answer the user's query. |
What is the biomedical concept corresponding to 'dna polymerase beta'? | [
"dna polymerase beta (homo sapiens)",
"polb (homo sapiens) (dna polymerase beta (homo sapiens))"
] | [
"dna polymerase iota (homo sapiens)",
"polg-beta (homo sapiens)",
"polgb (homo sapiens)",
"dna polymerase epsilon, catalytic subunit (homo sapiens)"
] | Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', answer the user's query. |
What is the biomedical concept corresponding to 'dna ligase iii'? | [
"dna ligase 3 (homo sapiens)",
"lig3 (homo sapiens) (dna ligase 3 (homo sapiens))"
] | [
"ligase iii, dna, atp-dependent (xenopus tropicalis)",
"ligase iii, dna, atp-dependent (danio rerio)",
"ligase iii, dna, atp-dependent (mus musculus)",
"ligase iv, dna, atp-dependent (xenopus tropicalis)"
] | Given the context 'Interestingly the amino terminus of the long-form aprataxin is homologous with polynucleotidekinase-3'-phosphatase, which has been demonstrated to be involved in base excision repair, a subtype of single-strand DNA break repair, through interaction with XRCC1, DNA polymerase beta, and DNA ligase III.', answer the user's query. |
What is the biomedical concept corresponding to 'aprataxin'? | [
"aprataxin (homo sapiens)"
] | [
"aprataxin (xenopus tropicalis)",
"aprataxin (drosophila melanogaster)",
"aprataxin-like (xenopus laevis)",
"aprataxin-like (arabidopsis thaliana)"
] | Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', answer the user's query. |
What is the biomedical concept corresponding to 'xrcc1'? | [
"xrcc1 (homo sapiens)",
"x-ray repair cross complementing 1 (homo sapiens)"
] | [
"xrcc1 (xenopus tropicalis) (x-ray repair complementing defective repair in chinese hamster cells 1 (xenopus tropicalis))",
"xrcc1 (xenopus tropicalis) (regulator of chromosome condensation 1 (xenopus tropicalis))",
"xrcc1 (xenopus laevis) (regulator of chromosome condensation 1 s homeolog (xenopus laevis))",
... | Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', answer the user's query. |
What is the biomedical concept corresponding to 'eaoh'? | [
"eaoh (homo sapiens)",
"eoaha (homo sapiens)"
] | [
"oohe (homo sapiens)",
"eaa1 (homo sapiens)",
"eay (drosophila melanogaster) (eyes absent (drosophila melanogaster))",
"yhae (escherichia coli str. k-12 substr. mg1655)"
] | Given the context 'These results strongly support the possibility that aprataxin and XRCC1 constitute a multiprotein complex and are involved in single-strand DNA break repair, and furthermore, that accumulation of unrepaired damaged DNA underlies the pathophysiological mechanisms of EAOH.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', answer the user's query. |
What is the biomedical concept corresponding to 'cytochrome c'? | [
"cytochrome c, somatic (homo sapiens)"
] | [
"cytochrome c1 (homo sapiens)",
"succinate dehydrogenase complex subunit c (homo sapiens)",
"cytochrome c (glycine max)",
"cytochrome c, somatic (oryctolagus cuniculus)"
] | Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', answer the user's query. |
What is the biomedical concept corresponding to 'caspase-9'? | [
"casp9 (homo sapiens)",
"caspase 9 (homo sapiens)"
] | [
"casp-8 (homo sapiens)",
"casp-7 (homo sapiens)",
"casp7 (homo sapiens)",
"casp8 (homo sapiens)"
] | Given the context 'Analysis of APAF-1 expression in human cutaneous melanoma progression.
APAF-1 plays a pivotal role in mitochondria-dependent apoptosis, binding to cytochrome c and favoring activation of caspase-9.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'It has been shown that epigenetic silencing of the APAF-1 gene is a common event in several metastatic melanoma cells in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'We determined, by Western blot, variation in the level of expression of APAF-1 in several human melanoma cell lines and, by immunohistochemistry, in a group of 106 histological samples including benign and malignant melanocytic lesions.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'We observed APAF-1 down-regulation or loss of expression in two metastatic melanoma cell lines, compared to primary melanoma cell lines.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'The immunohistochemical analysis revealed a significant difference in APAF-1 staining between nevi and melanomas.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'In addition, we found a significant negative correlation between APAF-1 expression level and tumor thickness and between primary melanomas and metastases.', answer the user's query. |
What is the biomedical concept corresponding to 'apaf-1'? | [
"apaf-1 (homo sapiens)",
"apaf1 (homo sapiens)",
"apoptotic peptidase activating factor 1 (homo sapiens)"
] | [
"apaf-3 (homo sapiens)",
"apa-1 (homo sapiens)",
"apa1 (homo sapiens)",
"apaf3 (homo sapiens)"
] | Given the context 'We conclude that loss of APAF-1 expression can be considered as an indicator of malignant transformation in melanoma.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'A human cDNA was cloned that encodes a DNA-binding protein (SATB1) that is expressed predominantly in thymus and binds selectively to the nuclear matrix/scaffold-associating DNAs (MARs/SARs).', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'Missing nucleoside experiments showed that SATB1 selectively binds in a special AT-rich sequence context where one strand consists of mixed A's, T's, and C's, excluding G's (ATC sequences).', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'When this feature is destroyed by mutation, SATB1 binding is greatly reduced even if the direct contact sequence remains intact.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'Conjunctional SATB1-binding sequences become stably unpaired in supercoiled DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'Specific mutations that diminish the unwinding potential greatly reduce SATB1 binding.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'However, SATB1 does not bind single-stranded DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'Chemical interference assays show that SATB1 binds along the minor groove with very little contact with the bases.', answer the user's query. |
What is the biomedical concept corresponding to 'satb1'? | [
"satb1 (homo sapiens)",
"satb homeobox 1 (homo sapiens)"
] | [
"satb1 (bos taurus)",
"satb2 (bos taurus)",
"sat1 (bos taurus)",
"satb1 (sus scrofa)"
] | Given the context 'This suggests that SATB1 recognizes the ATC sequence indirectly through the altered sugar-phosphate backbone structure present in the double-stranded DNA.', answer the user's query. |
What is the biomedical concept corresponding to 'angiotensin ii type 1 receptor'? | [
"angiotensin ii receptor type 1 (homo sapiens)",
"agtr1 (homo sapiens)",
"at1r (homo sapiens)",
"at1br (homo sapiens)",
"at2r1 (homo sapiens)"
] | [
"angiotensin ii receptor type 2 (homo sapiens)",
"angiotensin ii receptor, type 1a (rattus norvegicus)",
"angiotensin ii receptor, type 1b (rattus norvegicus)"
] | Given the context 'Cloning and characterization of a human angiotensin II type 1 receptor.
', answer the user's query. |
What is the biomedical concept corresponding to 'type 1 angiotensin ii receptor'? | [
"angiotensin ii receptor, type 1a (rattus norvegicus)"
] | [
"angiotensin ii receptor type 1 (homo sapiens)",
"agtr1 (homo sapiens)",
"at1r (homo sapiens)",
"at1br (homo sapiens)"
] | Given the context 'A human liver cDNA library was screened using a rat type 1 angiotensin II receptor cDNA coding sequence as a probe.', answer the user's query. |
What is the biomedical concept corresponding to 'type 1 angiotensin ii receptor'? | [
"angiotensin ii receptor type 1 (homo sapiens)",
"agtr1 (homo sapiens)",
"at1r (homo sapiens)",
"at1br (homo sapiens)",
"at1 (homo sapiens) (angiotensin ii receptor type 1 (homo sapiens))"
] | [
"angiotensin ii receptor type 2 (homo sapiens)",
"angiotensin ii receptor, type 1a (rattus norvegicus)",
"angiotensin ii receptor, type 1b (rattus norvegicus)"
] | Given the context 'Ligand binding studies of the cloned receptor expressed in COS cells suggested that it is pharmacologically a type 1 angiotensin II receptor subtype.', answer the user's query. |
What is the biomedical concept corresponding to 'me31b'? | [
"me31b (drosophila melanogaster)",
"maternal expression at 31b (drosophila melanogaster)"
] | [
"me31b (xenopus tropicalis)",
"sec31 homolog b, copii coat complex component (mus musculus)",
"mg33b (mus musculus)",
"krt33b (mus musculus)"
] | Given the context 'The predicted amino acid sequence shares a striking homology (75% identical) with the female germline-specific RNA helicase ME31B gene of Drosophila.', answer the user's query. |
What is the biomedical concept corresponding to 'me31b'? | [
"me31b (drosophila melanogaster)",
"maternal expression at 31b (drosophila melanogaster)"
] | [
"me31b (xenopus tropicalis)",
"sec31 homolog b, copii coat complex component (mus musculus)",
"mg33b (mus musculus)",
"krt33b (mus musculus)"
] | Given the context 'Unlike ME31B, however, the new gene expresses an abundant transcript in a large number of adult tissues and its 5' non-coding region was found split in a t(11;14)(q23.3;q32.3) cell line from a diffuse large B-cell lymphoma.', answer the user's query. |
What is the biomedical concept corresponding to 'n-myc'? | [
"n-myc (homo sapiens)",
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"nmyc (homo sapiens)"
] | [
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"n-myc (mus musculus)",
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))"
] | Given the context 'Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.
', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'The gene termed heir-1 was localized to the neuroblastoma consensus deletion at 1p36.2-p36.12.', answer the user's query. |
What is the biomedical concept corresponding to 'hlh462'? | [
"hlh462 (mus musculus)"
] | [
"lethal (2) 46eh (drosophila melanogaster)",
"cg46462 (drosophila melanogaster)",
"lethal (1) g0462 (drosophila melanogaster)",
"lethal (1) hm452 (drosophila melanogaster)"
] | Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'id'? | [
"id (mus musculus)"
] | [
"id (homo sapiens)",
"ids (homo sapiens)",
"id1 (danio rerio)",
"iddhisd (homo sapiens)"
] | Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'emc'? | [
"emc (drosophila melanogaster)"
] | [
"emc1 (mus musculus)",
"er membrane complex subunit emc3 (saccharomyces cerevisiae s288c)",
"emc-3 (caenorhabditis elegans)",
"emc3 (mus musculus)"
] | Given the context 'Its predicted protein is 95.8% identical to the mouse HLH462 protein and has clear homology to the mouse Id and Drosophila emc proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'Heir-1 does not encode a basic DNA binding domain as found in basic HLH proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'Despite prominent heir-1 expression in adrenal medulla, which is a prime target for neuroblastomas, 10 out of 12 neuroblastoma-derived cell lines revealed very low levels of heir-1 mRNA.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'Despite prominent heir-1 expression in adrenal medulla, which is a prime target for neuroblastomas, 10 out of 12 neuroblastoma-derived cell lines revealed very low levels of heir-1 mRNA.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', answer the user's query. |
What is the biomedical concept corresponding to 'n-myc'? | [
"n-myc (homo sapiens)",
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"nmyc (homo sapiens)"
] | [
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"n-myc (mus musculus)",
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))"
] | Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', answer the user's query. |
What is the biomedical concept corresponding to 'n-myc'? | [
"n-myc (homo sapiens)",
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"nmyc (homo sapiens)"
] | [
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"n-myc (mus musculus)",
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))"
] | Given the context 'Low heir-1 expression was generally found in tumor cell lines with N-myc overexpression, whereas the two cell lines displaying high heir-1 levels did not overexpress N-myc.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'We conclude that heir-1 expression is reduced specifically in the majority of neuroblastomas and suggest an inverse correlation between heir-1 and N-myc expression in neuroblastoma tumors and in embryonic development.', answer the user's query. |
What is the biomedical concept corresponding to 'heir-1'? | [
"heir-1 (homo sapiens)"
] | [
"heil1 (homo sapiens)",
"hrt-1 (homo sapiens)",
"he1 (homo sapiens)",
"heew1 (homo sapiens)"
] | Given the context 'We conclude that heir-1 expression is reduced specifically in the majority of neuroblastomas and suggest an inverse correlation between heir-1 and N-myc expression in neuroblastoma tumors and in embryonic development.', answer the user's query. |
What is the biomedical concept corresponding to 'n-myc'? | [
"n-myc (homo sapiens)",
"mycn proto-oncogene, bhlh transcription factor (homo sapiens)",
"nmyc (homo sapiens)"
] | [
"v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus)",
"n-myc (mus musculus)",
"myc proto-oncogene, bhlh transcription factor (homo sapiens)",
"myc (mus musculus) (myelocytomatosis oncogene (mus musculus))"
] | Given the context 'We conclude that heir-1 expression is reduced specifically in the majority of neuroblastomas and suggest an inverse correlation between heir-1 and N-myc expression in neuroblastoma tumors and in embryonic development.', answer the user's query. |
What is the biomedical concept corresponding to 'hnrnp u'? | [
"hnrnpu (homo sapiens)",
"hnrnp u (homo sapiens)",
"heterogeneous nuclear ribonucleoprotein u (homo sapiens)",
"hnrpu (homo sapiens)"
] | [
"hnrnpu (mus musculus)",
"hnrnpu (xenopus tropicalis)",
"heterogeneous nuclear ribonucleoprotein u (mus musculus)",
"hnrnpup1 (homo sapiens)"
] | Given the context 'Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box.
', answer the user's query. |
What is the biomedical concept corresponding to 'hnrnp u'? | [
"hnrnpu (homo sapiens)",
"hnrnp u (homo sapiens)",
"heterogeneous nuclear ribonucleoprotein u (homo sapiens)",
"hnrpu (homo sapiens)"
] | [
"hnrnpu (mus musculus)",
"hnrnpu (xenopus tropicalis)",
"heterogeneous nuclear ribonucleoprotein u (mus musculus)",
"hnrnpup1 (homo sapiens)"
] | Given the context 'The hnRNP U protein is an abundant nucleoplasmic phosphoprotein that is the largest of the major hnRNP proteins (120 kDa by SDS-PAGE).', answer the user's query. |
What is the biomedical concept corresponding to 'hnrnp u'? | [
"hnrnpu (homo sapiens)",
"hnrnp u (homo sapiens)",
"heterogeneous nuclear ribonucleoprotein u (homo sapiens)",
"hnrpu (homo sapiens)"
] | [
"hnrnpu (mus musculus)",
"hnrnpu (xenopus tropicalis)",
"heterogeneous nuclear ribonucleoprotein u (mus musculus)",
"hnrnpup1 (homo sapiens)"
] | Given the context 'HnRNP U binds pre-mRNA in vivo and binds both RNA and ssDNA in vitro.', answer the user's query. |
What is the biomedical concept corresponding to 'hnrnp u'? | [
"hnrnpu (homo sapiens)",
"hnrnp u (homo sapiens)",
"heterogeneous nuclear ribonucleoprotein u (homo sapiens)",
"hnrpu (homo sapiens)"
] | [
"hnrnpu (mus musculus)",
"hnrnpu (xenopus tropicalis)",
"heterogeneous nuclear ribonucleoprotein u (mus musculus)",
"hnrnpup1 (homo sapiens)"
] | Given the context 'Here we describe the cloning and sequencing of a cDNA encoding the hnRNP U protein, the determination of its amino acid sequence and the delineation of a region in this protein that confers RNA binding.', answer the user's query. |
What is the biomedical concept corresponding to 'hnrnp u'? | [
"hnrnpu (homo sapiens)",
"hnrnp u (homo sapiens)",
"heterogeneous nuclear ribonucleoprotein u (homo sapiens)",
"hnrpu (homo sapiens)"
] | [
"hnrnpu (mus musculus)",
"hnrnpu (xenopus tropicalis)",
"heterogeneous nuclear ribonucleoprotein u (mus musculus)",
"hnrnpup1 (homo sapiens)"
] | Given the context 'The predicted amino acid sequence of hnRNP U contains 806 amino acids (88,939 Daltons), and shows no extensive homology to any known proteins.', answer the user's query. |
What is the biomedical concept corresponding to 'cytoskeletal protein 4.1'? | [
"erythrocyte membrane protein band 4.1 (homo sapiens)"
] | [
"erythrocyte membrane protein band 4.1 (bos taurus)",
"erythrocyte membrane protein band 4.1 like 4a (homo sapiens)",
"erythrocyte membrane protein band 4.1 (xenopus tropicalis)",
"erythrocyte membrane protein band 4.1 like 1 (homo sapiens)"
] | Given the context 'Identification, cloning, and expression of a cytosolic megakaryocyte protein-tyrosine-phosphatase with sequence homology to cytoskeletal protein 4.1.
', answer the user's query. |
What is the biomedical concept corresponding to 'ptpase meg'? | [
"ptpmeg (homo sapiens)",
"ptpmeg1 (homo sapiens)"
] | [
"ptpe (mus musculus)",
"ptp-meg (drosophila melanogaster)",
"ptpmeg (mus musculus)",
"protein tyrosine phosphatase meg (drosophila melanogaster)"
] | Given the context 'We screened human megakaryoblastic cell line (MEG-01) an umbilical vein endothelial cell cDNA libraries to obtain a 3.7-kilobase cDNA designated PTPase MEG.', answer the user's query. |
What is the biomedical concept corresponding to 'ptpase meg'? | [
"ptpmeg (homo sapiens)",
"ptpmeg1 (homo sapiens)"
] | [
"ptpe (mus musculus)",
"ptp-meg (drosophila melanogaster)",
"ptpmeg (mus musculus)",
"protein tyrosine phosphatase meg (drosophila melanogaster)"
] | Given the context 'PTPase MEG cDNA contains an open reading frame of 926 amino acids.', answer the user's query. |
What is the biomedical concept corresponding to 'erythrocyte protein 4.1'? | [
"erythrocyte membrane protein band 4.1 (homo sapiens)"
] | [
"erythrocyte membrane protein band 4.1 like 4a (homo sapiens)",
"erythrocyte membrane protein band 4.1 like 1 (homo sapiens)",
"erythrocyte membrane protein band 4.2 (homo sapiens)",
"erythrocyte membrane protein band 4.1 like 4b (homo sapiens)"
] | Given the context 'The amino-terminal region (amino acids 31-367) is 45% identical to the amino terminus of human erythrocyte protein 4.1, a cytoskeletal protein.', answer the user's query. |
What is the biomedical concept corresponding to 'receptor for ciliary neurotrophic factor'? | [
"ciliary neurotrophic factor receptor (homo sapiens)"
] | [
"ciliary neurotrophic factor receptor (xenopus tropicalis)",
"ciliary neurotrophic factor receptor (rattus norvegicus)",
"ciliary neurotrophic factor receptor (danio rerio)",
"ciliary neurotrophic factor receptor (mus musculus)"
] | Given the context 'The receptor for ciliary neurotrophic factor.
', answer the user's query. |
What is the biomedical concept corresponding to 'receptor for ciliary neurotrophic factor'? | [
"ciliary neurotrophic factor receptor (homo sapiens)"
] | [
"ciliary neurotrophic factor receptor (xenopus tropicalis)",
"ciliary neurotrophic factor receptor (rattus norvegicus)",
"ciliary neurotrophic factor receptor (danio rerio)",
"ciliary neurotrophic factor receptor (mus musculus)"
] | Given the context 'A " tagged-ligand panning " procedure was used to clone a receptor for ciliary neurotrophic factor (CNTF).', answer the user's query. |
What is the biomedical concept corresponding to 'cntf'? | [
"cntf (homo sapiens)",
"ciliary neurotrophic factor (homo sapiens)",
"hcntf (homo sapiens)"
] | [
"cntf (rattus norvegicus)",
"cntf (xenopus tropicalis)",
"cntfr (homo sapiens)",
"cntn1 (homo sapiens)"
] | Given the context 'A " tagged-ligand panning " procedure was used to clone a receptor for ciliary neurotrophic factor (CNTF).', answer the user's query. |
What is the biomedical concept corresponding to 'cntf receptor'? | [
"cntfr (homo sapiens)",
"ciliary neurotrophic factor receptor (homo sapiens)"
] | [
"ciliary neurotrophic factor receptor (rattus norvegicus)",
"ciliary neurotrophic factor receptor (xenopus tropicalis)",
"ntn1r1 (homo sapiens)",
"cntfr (rattus norvegicus)"
] | Given the context 'The CNTF receptor has a structure unrelated to the receptors utilized by the nerve growth factor family of neurotrophic molecules, but instead is most homologous to the receptor for a cytokine, interleukin-6.', answer the user's query. |
What is the biomedical concept corresponding to 'interleukin-6'? | [
"interleukin 6 (homo sapiens)",
"il-6 (homo sapiens)",
"il6 (homo sapiens)",
"cdf (homo sapiens) (interleukin 6 (homo sapiens))",
"hgf (homo sapiens) (interleukin 6 (homo sapiens))"
] | [
"lif interleukin 6 family cytokine (homo sapiens)",
"interleukin 7 (homo sapiens)",
"il7 (homo sapiens)",
"cdf (homo sapiens) (lif interleukin 6 family cytokine (homo sapiens))"
] | Given the context 'The CNTF receptor has a structure unrelated to the receptors utilized by the nerve growth factor family of neurotrophic molecules, but instead is most homologous to the receptor for a cytokine, interleukin-6.', answer the user's query. |
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