instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'The altered promoter function of the V-LHbeta gene provides evidence for differences in regulation of the wt- and V-LHbeta genes, which may contribute to the differences observed in pituitary-gonadal function between carriers of the two LHbeta alleles.', select the correct biomedical concept corresponding to 'lhbeta'. Answer using one of the provided options. | <Options>: A: lutropin subunit beta (bos taurus) (aka lutropin subunit beta)
B: luteinizing hormone subunit beta (homo sapiens) (aka luteinizing hormone subunit beta)
C: lutropin subunit beta-like (xenopus tropicalis) (aka lutropin subunit beta-like)
D: luteinizing hormone subunit beta (xenopus tropicalis) (aka luteinizing hormone subunit beta)
E: lutropin subunit beta-like (xenopus laevis) (aka lutropin subunit beta-like)
F: None of the above. | B |
<Instruct>: Given the context 'The altered promoter function of the V-LHbeta gene provides evidence for differences in regulation of the wt- and V-LHbeta genes, which may contribute to the differences observed in pituitary-gonadal function between carriers of the two LHbeta alleles.', select the correct biomedical concept corresponding to 'lhbeta'. Answer using one of the provided options. | <Options>: A: luteinizing hormone subunit beta (oryctolagus cuniculus) (aka luteinizing hormone subunit beta)
B: lutropin subunit beta-like (xenopus laevis) (aka lutropin subunit beta-like)
C: lutropin subunit beta-like (xenopus tropicalis) (aka lutropin subunit beta-like)
D: luteinizing hormone subunit beta (homo sapiens) (aka luteinizing hormone subunit beta)
E: luteinizing hormone subunit beta (sus scrofa) (aka luteinizing hormone subunit beta)
F: None of the above. | D |
<Instruct>: Given the context 'The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.
', select the correct biomedical concept corresponding to 'hydroxypyruvate reductase'. Answer using one of the provided options. | <Options>: A: hydroxypyruvate reductase 3 (arabidopsis thaliana) (aka d-isomer specific 2-hydroxyacid dehydrogenase family protein)
B: glyoxylate and hydroxypyruvate reductase (bos taurus) (aka glyoxylate and hydroxypyruvate reductase)
C: grhpr (xenopus tropicalis) (glyoxylate reductase/hydroxypyruvate reductase, gene 1 (xenopus tropicalis)) (aka glyoxylate reductase/hydroxypyruvate reductase, gene 1)
D: glyoxylate and hydroxypyruvate reductase (rattus norvegicus) (aka glyoxylate and hydroxypyruvate reductase)
E: glyoxylate and hydroxypyruvate reductase (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
F: None of the above. | E |
<Instruct>: Given the context 'The gene encoding hydroxypyruvate reductase (GRHPR) is mutated in patients with primary hyperoxaluria type II.
', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: prolactin releasing hormone receptor (homo sapiens) (aka prolactin releasing hormone receptor)
B: grr1 (glycine max) (aka putative ein3-binding f-box protein)
C: grhpr (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
D: ghrhr (homo sapiens) (aka growth hormone releasing hormone receptor)
E: gr (homo sapiens) (aka nuclear receptor subfamily 3 group c member 1)
F: None of the above. | C |
<Instruct>: Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', select the correct biomedical concept corresponding to 'glyoxylate reductase'. Answer using one of the provided options. | <Options>: A: glyoxylate reductase 1 homolog (homo sapiens) (aka glyoxylate reductase 1 homolog)
B: glyoxylate and hydroxypyruvate reductase (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
C: reductase (glycine max) (aka chalcone reductase chr1)
D: glyoxylate reductase (escherichia coli str. k-12 substr. mg1655) (aka glyoxylate reductase)
E: glyoxylate reductase 1 homolog (sus scrofa) (aka glyoxylate reductase 1 homolog)
F: None of the above. | B |
<Instruct>: Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', select the correct biomedical concept corresponding to 'hydroxypyruvate reductase'. Answer using one of the provided options. | <Options>: A: hdhpr (homo sapiens) (aka quinoid dihydropteridine reductase)
B: glyoxylate/hydroxypyruvate reductase a (escherichia coli str. k-12 substr. mg1655) (aka glyoxylate/hydroxypyruvate reductase a)
C: hydroxypyruvate reductase (arabidopsis thaliana) (aka hydroxypyruvate reductase)
D: grhpr (xenopus tropicalis) (glyoxylate reductase/hydroxypyruvate reductase, gene 1 (xenopus tropicalis)) (aka glyoxylate reductase/hydroxypyruvate reductase, gene 1)
E: glyoxylate and hydroxypyruvate reductase (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
F: None of the above. | E |
<Instruct>: Given the context 'We identified a glyoxylate reductase/hydroxypyruvate reductase (GRHPR) cDNA clone from a human liver expressed sequence tag (EST) library.', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: ghrhr (homo sapiens) (aka growth hormone releasing hormone receptor)
B: gr (homo sapiens) (aka nuclear receptor subfamily 3 group c member 1)
C: grr1 (glycine max) (aka putative ein3-binding f-box protein)
D: prolactin releasing hormone receptor (homo sapiens) (aka prolactin releasing hormone receptor)
E: grhpr (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
F: None of the above. | E |
<Instruct>: Given the context 'Transient transfection of the cDNA clone into COS cells verified that it encoded an enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities.', select the correct biomedical concept corresponding to 'glyoxylate reductase'. Answer using one of the provided options. | <Options>: A: glyoxylate and hydroxypyruvate reductase (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
B: glyoxylate/succinic semialdehyde reductase 1 (glycine max) (aka glyoxylate/succinic semialdehyde reductase 1)
C: glyoxylate reductase 1 homolog (bos taurus) (aka glyoxylate reductase 1 homolog)
D: reductase (glycine max) (aka chalcone reductase chr1)
E: glyoxylate reductase 1 homolog (rattus norvegicus) (aka glyoxylate reductase 1 homolog)
F: None of the above. | A |
<Instruct>: Given the context 'The genomic structure of the human GRHPR gene was determined and contains nine exons and eight introns and spans approximately 9 kb pericentromeric on chromosome 9.', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: ghrfr (homo sapiens) (aka growth hormone releasing hormone receptor)
B: grhr (homo sapiens) (aka gonadotropin releasing hormone receptor)
C: grpr (homo sapiens) (aka gastrin releasing peptide receptor)
D: grhpr (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
E: grr1 (glycine max) (aka putative ein3-binding f-box protein)
F: None of the above. | D |
<Instruct>: Given the context 'The genomic structure of the human GRHPR gene was determined and contains nine exons and eight introns and spans approximately 9 kb pericentromeric on chromosome 9.', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
B: grpr (homo sapiens) (aka gastrin releasing peptide receptor)
C: grr1 (glycine max) (aka putative ein3-binding f-box protein)
D: ghrfr (homo sapiens) (aka growth hormone releasing hormone receptor)
E: prolactin releasing hormone receptor (homo sapiens) (aka prolactin releasing hormone receptor)
F: None of the above. | F |
<Instruct>: Given the context 'Four PH2 patients representing two pairs of siblings from two unrelated families were analyzed for mutations in GRHPR by single strand conformation polymorphism analysis.', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: grhpr (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
B: prolactin releasing hormone receptor (homo sapiens) (aka prolactin releasing hormone receptor)
C: grhr (homo sapiens) (aka gonadotropin releasing hormone receptor)
D: grr1 (glycine max) (aka putative ein3-binding f-box protein)
E: gr (homo sapiens) (aka nuclear receptor subfamily 3 group c member 1)
F: None of the above. | A |
<Instruct>: Given the context 'The cDNA that we have identified represents the first characterization of an animal GRHPR sequence.', select the correct biomedical concept corresponding to 'grhpr'. Answer using one of the provided options. | <Options>: A: grhpr (homo sapiens) (aka glyoxylate and hydroxypyruvate reductase)
B: ghrhr (homo sapiens) (aka growth hormone releasing hormone receptor)
C: gr (homo sapiens) (aka nuclear receptor subfamily 3 group c member 1)
D: grpr (homo sapiens) (aka gastrin releasing peptide receptor)
E: prolactin releasing hormone receptor (homo sapiens) (aka prolactin releasing hormone receptor)
F: None of the above. | A |
<Instruct>: Given the context 'Ectodysplasin is a collagenous trimeric type II membrane protein with a tumor necrosis factor-like domain and co-localizes with cytoskeletal structures at lateral and apical surfaces of cells.
', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
B: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
C: ectodysplasin a (danio rerio) (aka ectodysplasin a)
D: ectodysplasin a receptor (homo sapiens) (aka ectodysplasin a receptor)
E: ectodysplasin a (homo sapiens) (aka ectodysplasin a)
F: None of the above. | E |
<Instruct>: Given the context 'Anhidrotic ectodermal dysplasia (EDA) is a human genetic disorder of impaired ectodermal appendage development.', select the correct biomedical concept corresponding to 'ectodermal dysplasia'. Answer using one of the provided options. | <Options>: A: asphixiating thoracic dystrophy (chondroectodermal dysplasia-like syndrome) (homo sapiens) (aka asphixiating thoracic dystrophy (chondroectodermal dysplasia-like syndrome))
B: otodental dysplasia chromosome deletion syndrome (homo sapiens) (aka otodental dysplasia chromosome deletion syndrome)
C: ectodermal dysplasia 8, hair/tooth/nail type (homo sapiens) (aka ectodermal dysplasia 8, hair/tooth/nail type)
D: embryonic ectoderm development (homo sapiens) (aka embryonic ectoderm development)
E: endove syndrome, limb-only type (homo sapiens) (aka endove syndrome, limb-only type)
F: None of the above. | F |
<Instruct>: Given the context 'Anhidrotic ectodermal dysplasia (EDA) is a human genetic disorder of impaired ectodermal appendage development.', select the correct biomedical concept corresponding to 'eda'. Answer using one of the provided options. | <Options>: A: eda1 (xenopus laevis) (ectodysplasin a s homeolog (xenopus laevis)) (aka ectodysplasin a s homeolog)
B: eda3 (homo sapiens) (ectodysplasin a receptor (homo sapiens)) (aka ectodysplasin a receptor)
C: edd (arabidopsis thaliana) (aka glycine-trna ligase)
D: eda (homo sapiens) (aka ectodysplasin a)
E: eda1 (arabidopsis thaliana) (aka f-box associated ubiquitination effector family protein)
F: None of the above. | D |
<Instruct>: Given the context 'The EDA gene encodes isoforms of a novel transmembrane protein, ectodysplasin.', select the correct biomedical concept corresponding to 'eda'. Answer using one of the provided options. | <Options>: A: eda1 (xenopus laevis) (ectodysplasin a s homeolog (xenopus laevis)) (aka ectodysplasin a s homeolog)
B: edd (arabidopsis thaliana) (aka glycine-trna ligase)
C: eda3 (homo sapiens) (ectodysplasin a receptor (homo sapiens)) (aka ectodysplasin a receptor)
D: ectd1 (homo sapiens) (ectodysplasin a (homo sapiens)) (aka ectodysplasin a)
E: eda1 (arabidopsis thaliana) (aka f-box associated ubiquitination effector family protein)
F: None of the above. | D |
<Instruct>: Given the context 'The EDA gene encodes isoforms of a novel transmembrane protein, ectodysplasin.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: hed (homo sapiens) (ectodysplasin a (homo sapiens)) (aka ectodysplasin a)
B: ectodysplasin a (bos taurus) (aka ectodysplasin a)
C: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
D: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
E: ectodysplasin a (danio rerio) (aka ectodysplasin a)
F: None of the above. | A |
<Instruct>: Given the context 'In order to understand better the function of the ectodysplasin protein molecule and its domains, we have studied the processing and localization of wild-type and mutated isoforms in transfected human fetal kidney 293 and monkey kidney COS-1 cells.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
B: ectodysplasin a (bos taurus) (aka ectodysplasin a)
C: ectodysplasin a (homo sapiens) (aka ectodysplasin a)
D: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
E: ectodysplasin a receptor (xenopus tropicalis) (aka ectodysplasin a receptor)
F: None of the above. | C |
<Instruct>: Given the context 'Similar to other members of collagenous membrane proteins and members of TNF-related ligands, ectodysplasin is a type II membrane protein and it forms trimers.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ectodysplasin a (homo sapiens) (aka ectodysplasin a)
B: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
C: ectodysplasin a (bos taurus) (aka ectodysplasin a)
D: ectodysplasin a receptor (homo sapiens) (aka ectodysplasin a receptor)
E: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
F: None of the above. | A |
<Instruct>: Given the context 'The membrane localization of ectodysplasin is asymmetrical: it is found on the apical and lateral surfaces of the cells where it co-localizes with cytoskeletal structures.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ectodysplasin a receptor (homo sapiens) (aka ectodysplasin a receptor)
B: ectodysplasin a (danio rerio) (aka ectodysplasin a)
C: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
D: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
E: ectodysplasin a (homo sapiens) (aka ectodysplasin a)
F: None of the above. | E |
<Instruct>: Given the context 'The membrane localization of ectodysplasin is asymmetrical: it is found on the apical and lateral surfaces of the cells where it co-localizes with cytoskeletal structures.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ed3 (homo sapiens) (ectodysplasin a receptor (homo sapiens)) (aka ectodysplasin a receptor)
B: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
C: ectodysplasin a (danio rerio) (aka ectodysplasin a)
D: ectodysplasin a (xenopus tropicalis) (aka ectodysplasin a)
E: ectodysplasin a receptor (xenopus tropicalis) (aka ectodysplasin a receptor)
F: None of the above. | F |
<Instruct>: Given the context 'Our results suggest that ectodysplasin is a new member in the TNF-related ligand family involved in the early epithelial-mesenchymal interaction that regulates ectodermal appendage formation.', select the correct biomedical concept corresponding to 'ectodysplasin'. Answer using one of the provided options. | <Options>: A: ectodysplasin a (danio rerio) (aka ectodysplasin a)
B: ectodysplasin a (homo sapiens) (aka ectodysplasin a)
C: ectodysplasin a (bos taurus) (aka ectodysplasin a)
D: ectodysplasin a (sus scrofa) (aka ectodysplasin a)
E: ectodysplasin a receptor (xenopus tropicalis) (aka ectodysplasin a receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Bcl-2 is the best characterized inhibitor of apoptosis, although the molecular basis of this action is not fully understood.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bi (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
B: bis (drosophila melanogaster) (aka bistre)
C: bis1 (mus musculus) (aka beta-carboline-induced seizures 1)
D: bis1 (homo sapiens) (aka ess-2 spliceosome associated protein)
E: bis (homo sapiens) (swi/snf related baf chromatin remodeling complex subunit atpase 2 (homo sapiens)) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
F: None of the above. | F |
<Instruct>: Given the context 'Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Bcl-2 is the best characterized inhibitor of apoptosis, although the molecular basis of this action is not fully understood.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: ccnb2 (homo sapiens) (aka cyclin b2)
B: bcl2 interacting protein 2 (homo sapiens) (aka bcl2 interacting protein 2)
C: bcl2l2 (homo sapiens) (aka bcl2 like 2)
D: bcl2 apoptosis regulator (homo sapiens) (aka bcl2 apoptosis regulator)
E: bcl-b (homo sapiens) (aka bcl2 like 10)
F: None of the above. | D |
<Instruct>: Given the context 'Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death.
Bcl-2 is the best characterized inhibitor of apoptosis, although the molecular basis of this action is not fully understood.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: bcl2 interacting protein 2 (homo sapiens) (aka bcl2 interacting protein 2)
B: ccnb2 (homo sapiens) (aka cyclin b2)
C: bcl2-l-2 (homo sapiens) (aka bcl2 like 2)
D: bcl2l (homo sapiens) (aka bcl2 like 1)
E: bcl2 (homo sapiens) (aka bcl2 apoptosis regulator)
F: None of the above. | E |
<Instruct>: Given the context 'Using a protein interaction cloning procedure, we identified a human gene designated as bis (mapped to chromosome 10q25) that encoded a novel Bcl-2-interacting protein.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bis (homo sapiens) (swi/snf related baf chromatin remodeling complex subunit atpase 2 (homo sapiens)) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
B: bisb (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin molybdotransferase)
C: bi (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
D: bisd (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin adenylyltransferase)
E: bis1 (mus musculus) (aka beta-carboline-induced seizures 1)
F: None of the above. | F |
<Instruct>: Given the context 'Bis protein showed no significant homology with Bcl-2 family proteins and had no prominent functional motif.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bisb (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin molybdotransferase)
B: bis (drosophila melanogaster) (aka bistre)
C: bis (homo sapiens) (swi/snf related baf chromatin remodeling complex subunit atpase 2 (homo sapiens)) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
D: bisc (drosophila melanogaster) (aka biscotti)
E: bis (mus musculus) (aka bcl2-associated athanogene 3)
F: None of the above. | F |
<Instruct>: Given the context 'Co-immunoprecipitation analysis confirmed that Bis interacted with Bcl-2 in vivo.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bisd (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin adenylyltransferase)
B: bis (mus musculus) (aka bcl2-associated athanogene 3)
C: bpids (homo sapiens) (aka ubiquitin protein ligase e3b)
D: bis (homo sapiens) (swi/snf related baf chromatin remodeling complex subunit atpase 2 (homo sapiens)) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
E: bi (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
F: None of the above. | F |
<Instruct>: Given the context 'Co-immunoprecipitation analysis confirmed that Bis interacted with Bcl-2 in vivo.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: bcl2 like 2 (homo sapiens) (aka bcl2 like 2)
B: bcl-2 (homo sapiens) (aka bcl2 apoptosis regulator)
C: ccnb2 (homo sapiens) (aka cyclin b2)
D: bcl-b (homo sapiens) (aka bcl2 like 10)
E: bcl2 interacting protein 2 (homo sapiens) (aka bcl2 interacting protein 2)
F: None of the above. | B |
<Instruct>: Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bis1 (homo sapiens) (aka ess-2 spliceosome associated protein)
B: bis1 (mus musculus) (aka beta-carboline-induced seizures 1)
C: bpids (homo sapiens) (aka ubiquitin protein ligase e3b)
D: bi (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
E: bisd (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin adenylyltransferase)
F: None of the above. | F |
<Instruct>: Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: bcl2 apoptosis regulator (homo sapiens) (aka bcl2 apoptosis regulator)
B: bcl2-l-2 (homo sapiens) (aka bcl2 like 2)
C: bcl2 interacting protein 2 (homo sapiens) (aka bcl2 interacting protein 2)
D: ccnb2 (homo sapiens) (aka cyclin b2)
E: bcl-b (homo sapiens) (aka bcl2 like 10)
F: None of the above. | A |
<Instruct>: Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: bcl2 interacting protein 2 (homo sapiens) (aka bcl2 interacting protein 2)
B: ccnb2 (homo sapiens) (aka cyclin b2)
C: bcl-b (homo sapiens) (aka bcl2 like 10)
D: bcl2 like 2 (homo sapiens) (aka bcl2 like 2)
E: bcl2l (homo sapiens) (aka bcl2 like 1)
F: None of the above. | F |
<Instruct>: Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', select the correct biomedical concept corresponding to 'bax'. Answer using one of the provided options. | <Options>: A: bcl2 associated x, apoptosis regulator (homo sapiens) (aka bcl2 associated x, apoptosis regulator)
B: bcl2 apoptosis regulator (homo sapiens) (aka bcl2 apoptosis regulator)
C: bcl-x (homo sapiens) (aka bcl2 like 1)
D: bak-2 (homo sapiens) (aka bcl2 antagonist/killer 1 pseudogene 1)
E: bak1 (homo sapiens) (aka bcl2 antagonist/killer 1)
F: None of the above. | A |
<Instruct>: Given the context 'DNA transfection experiments indicated that Bis itself exerted only weak anti-apoptotic activity, but was synergistic with Bcl-2 in preventing Bax-induced and Fas-mediated apoptosis.', select the correct biomedical concept corresponding to 'fas'. Answer using one of the provided options. | <Options>: A: fas (gallus gallus) (aka fas cell surface death receptor)
B: fas (homo sapiens) (fas cell surface death receptor (homo sapiens)) (aka fas cell surface death receptor)
C: fas (homo sapiens) (fatty acid synthase (homo sapiens)) (aka fatty acid synthase)
D: fasas (homo sapiens) (aka fas antisense rna 1)
E: fasps (homo sapiens) (aka period circadian regulator 2)
F: None of the above. | B |
<Instruct>: Given the context 'These results suggest that Bis is a novel modulator of cellular anti-apoptotic activity that functions through its interaction with Bcl-2.', select the correct biomedical concept corresponding to 'bis'. Answer using one of the provided options. | <Options>: A: bis (drosophila melanogaster) (aka bistre)
B: bis1 (mus musculus) (aka beta-carboline-induced seizures 1)
C: bisb (escherichia coli str. k-12 substr. mg1655) (aka molybdopterin molybdotransferase)
D: bis (homo sapiens) (swi/snf related baf chromatin remodeling complex subunit atpase 2 (homo sapiens)) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
E: bpids (homo sapiens) (aka ubiquitin protein ligase e3b)
F: None of the above. | F |
<Instruct>: Given the context 'These results suggest that Bis is a novel modulator of cellular anti-apoptotic activity that functions through its interaction with Bcl-2.', select the correct biomedical concept corresponding to 'bcl-2'. Answer using one of the provided options. | <Options>: A: bcl2 (homo sapiens) (aka bcl2 apoptosis regulator)
B: bcl-b (homo sapiens) (aka bcl2 like 10)
C: bcl2l2 (homo sapiens) (aka bcl2 like 2)
D: bcl2l (homo sapiens) (aka bcl2 like 1)
E: ccnb2 (homo sapiens) (aka cyclin b2)
F: None of the above. | A |
<Instruct>: Given the context 'BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
BACKGROUND: Treatment of breast cancer with the antiestrogen tamoxifen is effective in approximately one half of the patients with estrogen receptor-positive disease, but tumors recur frequently because of the development of metastases that are resistant to tamoxifen.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bca1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
B: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
C: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
D: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
E: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
F: None of the above. | D |
<Instruct>: Given the context 'BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
BACKGROUND: Treatment of breast cancer with the antiestrogen tamoxifen is effective in approximately one half of the patients with estrogen receptor-positive disease, but tumors recur frequently because of the development of metastases that are resistant to tamoxifen.', select the correct biomedical concept corresponding to 'p130cas'. Answer using one of the provided options. | <Options>: A: p130cas (homo sapiens) (aka bcar1 scaffold protein, cas family member)
B: p130cas (xenopus laevis) (bcar1, cas family scaffold protein s homeolog (xenopus laevis)) (aka bcar1, cas family scaffold protein s homeolog)
C: p130cas (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
D: p130cas (sus scrofa) (aka bcar1 scaffold protein, cas family member)
E: p120cas (xenopus tropicalis) (aka catenin delta 1)
F: None of the above. | A |
<Instruct>: Given the context 'In this study, we isolated and characterized the crucial gene at the breast cancer antiestrogen resistance 1 (BCAR1) locus.', select the correct biomedical concept corresponding to 'breast cancer antiestrogen resistance 1'. Answer using one of the provided options. | <Options>: A: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
B: breast cancer anti-estrogen resistance 4 (homo sapiens) (aka breast cancer anti-estrogen resistance 4)
C: breast cancer anti-estrogen resistance 1 (mus musculus) (aka breast cancer anti-estrogen resistance 1)
D: bcar3 antisense rna 1 (homo sapiens) (aka bcar3 antisense rna 1)
E: breast cancer associated esr1 regulating natural antisense transcript 1 (homo sapiens) (aka breast cancer associated esr1 regulating natural antisense transcript 1)
F: None of the above. | A |
<Instruct>: Given the context 'In this study, we isolated and characterized the crucial gene at the breast cancer antiestrogen resistance 1 (BCAR1) locus.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1 (bos taurus) (aka bcar1 scaffold protein, cas family member)
B: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
D: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
E: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
F: None of the above. | B |
<Instruct>: Given the context 'Transfer of the BCAR1 locus from retrovirus-mutated, antiestrogen-resistant cells to estrogen-dependent ZR-75-1 cells by cell fusion conferred an antiestrogen-resistant phenotype on the recipient cells.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
B: bcar1 (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
D: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
E: bcar1 (bos taurus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | B |
<Instruct>: Given the context 'The complete coding sequence of BCAR1 was isolated by use of exon-trapping and complementary DNA (cDNA) library screening.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
B: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
C: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
D: bcar1 scaffold protein, cas family member (bos taurus) (aka bcar1 scaffold protein, cas family member)
E: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
F: None of the above. | A |
<Instruct>: Given the context 'The complete coding sequence of BCAR1 was isolated by use of exon-trapping and complementary DNA (cDNA) library screening.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1 pseudogene 1 (homo sapiens) (aka bcar1 pseudogene 1)
B: bca1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
C: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
D: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
E: bcar1 scaffold protein, cas family member (bos taurus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | F |
<Instruct>: Given the context 'Sequence analysis of human BCAR1 cDNA predicted a protein of 870 amino acids that was strongly homologous to rat p130Cas-adapter protein.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
B: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
C: bcar1 scaffold protein, cas family member (bos taurus) (aka bcar1 scaffold protein, cas family member)
D: bcar1 (homo sapiens) (aka bcar1 scaffold protein, cas family member)
E: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
F: None of the above. | D |
<Instruct>: Given the context 'Sequence analysis of human BCAR1 cDNA predicted a protein of 870 amino acids that was strongly homologous to rat p130Cas-adapter protein.', select the correct biomedical concept corresponding to 'p130cas-adapter protein'. Answer using one of the provided options. | <Options>: A: p130cas (xenopus laevis) (bcar1, cas family scaffold protein s homeolog (xenopus laevis)) (aka bcar1, cas family scaffold protein s homeolog)
B: p130cas (sus scrofa) (aka bcar1 scaffold protein, cas family member)
C: cas1 (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
D: p130cas (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
E: p130cas (rattus norvegicus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | E |
<Instruct>: Given the context 'Genomic analysis revealed that BCAR1 consists of seven exons and is located at chromosome 16q23.1.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
B: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
C: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
D: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
E: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
F: None of the above. | C |
<Instruct>: Given the context 'BCAR1 transcripts were detected in multiple human tissues and were similar in size to transcripts produced by retrovirus-mutated ZR-75-1 cells.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bca1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
B: bcar1 (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
D: bcar1 scaffold protein, cas family member (bos taurus) (aka bcar1 scaffold protein, cas family member)
E: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
F: None of the above. | B |
<Instruct>: Given the context 'Transfection of BCAR1 cDNA into ZR-75-1 cells again resulted in sustained cell proliferation in the presence of antiestrogens, confirming that BCAR1 was the responsible gene in the locus.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bca1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
B: bcar1 (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
D: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
E: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
F: None of the above. | B |
<Instruct>: Given the context 'Transfection of BCAR1 cDNA into ZR-75-1 cells again resulted in sustained cell proliferation in the presence of antiestrogens, confirming that BCAR1 was the responsible gene in the locus.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1 pseudogene 1 (homo sapiens) (aka bcar1 pseudogene 1)
B: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
D: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
E: bcar1 (bos taurus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | B |
<Instruct>: Given the context 'Overexpression of the BCAR1 gene confers antiestrogen resistance on human ZR-75-1 breast cancer cells.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
B: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
C: bcar1p1 (homo sapiens) (aka bcar1 pseudogene 1)
D: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
E: bcar1 (bos taurus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | B |
<Instruct>: Given the context 'Overexpression of BCAR1 in retrovirus-mutated cells appears to result from activation of the gene's promoter.', select the correct biomedical concept corresponding to 'bcar1'. Answer using one of the provided options. | <Options>: A: bcar1 pseudogene 1 (homo sapiens) (aka bcar1 pseudogene 1)
B: bca-1 (homo sapiens) (aka c-x-c motif chemokine ligand 13)
C: bcar2 (homo sapiens) (aka transcriptional regulating factor 1)
D: bcar1 (xenopus tropicalis) (aka bcar1, cas family scaffold protein)
E: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | E |
<Instruct>: Given the context 'Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules.
', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd207 molecule (homo sapiens) (aka cd207 molecule)
B: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
C: cd20l (homo sapiens) (aka membrane spanning 4-domains a3)
D: cd209 antigen-like protein a (xenopus tropicalis) (clec9a (xenopus tropicalis)) (aka cd209 antigen-like protein a)
E: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
F: None of the above. | A |
<Instruct>: Given the context 'We have identified a type II Ca2+-dependent lectin displaying mannose-binding specificity, exclusively expressed by Langerhans cells (LC), and named Langerin.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd206 (homo sapiens) (aka mannose receptor c-type 1)
B: cd20-like (xenopus tropicalis) (aka membrane spanning 4-domains a1)
C: cd207 molecule (homo sapiens) (aka cd207 molecule)
D: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
E: cd20l7 (homo sapiens) (aka membrane spanning 4-domains a10)
F: None of the above. | C |
<Instruct>: Given the context 'We have identified a type II Ca2+-dependent lectin displaying mannose-binding specificity, exclusively expressed by Langerhans cells (LC), and named Langerin.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd20l (homo sapiens) (aka membrane spanning 4-domains a3)
B: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
C: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
D: cd206 (homo sapiens) (aka mannose receptor c-type 1)
E: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
F: None of the above. | F |
<Instruct>: Given the context 'Here, we have shown that Langerin is constitutively associated with BG and that antibody to Langerin is internalized into these structures.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd20-like (xenopus tropicalis) (aka membrane spanning 4-domains a1)
B: cd209 antigen-like protein a (xenopus tropicalis) (clec9a (xenopus tropicalis)) (aka cd209 antigen-like protein a)
C: cd207 (homo sapiens) (aka cd207 molecule)
D: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
E: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
F: None of the above. | C |
<Instruct>: Given the context 'Here, we have shown that Langerin is constitutively associated with BG and that antibody to Langerin is internalized into these structures.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd20-like (xenopus tropicalis) (aka membrane spanning 4-domains a1)
B: cd206 (homo sapiens) (aka mannose receptor c-type 1)
C: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
D: cd207 (homo sapiens) (aka cd207 molecule)
E: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
F: None of the above. | D |
<Instruct>: Given the context 'Remarkably, transfection of Langerin cDNA into fibroblasts created a compact network of membrane structures with typical features of BG.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
B: cd20l (homo sapiens) (aka membrane spanning 4-domains a3)
C: cd207 (homo sapiens) (aka cd207 molecule)
D: cd208 (homo sapiens) (aka lysosomal associated membrane protein 3)
E: cd20l7 (homo sapiens) (aka membrane spanning 4-domains a10)
F: None of the above. | C |
<Instruct>: Given the context 'Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd207 molecule (homo sapiens) (aka cd207 molecule)
B: cd20-like (xenopus tropicalis) (aka membrane spanning 4-domains a1)
C: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
D: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
E: cd209 antigen-like protein a (xenopus tropicalis) (clec9a (xenopus tropicalis)) (aka cd209 antigen-like protein a)
F: None of the above. | A |
<Instruct>: Given the context 'Our data suggest that induction of BG is a consequence of the antigen-capture function of Langerin, allowing routing into these organelles and providing access to a nonclassical antigen-processing pathway.', select the correct biomedical concept corresponding to 'langerin'. Answer using one of the provided options. | <Options>: A: cd20l1 (homo sapiens) (aka membrane spanning 4-domains a4a)
B: cd20l7 (homo sapiens) (aka membrane spanning 4-domains a10)
C: cd207 (homo sapiens) (aka cd207 molecule)
D: cd206 (homo sapiens) (aka mannose receptor c-type 1)
E: cd20l5 (homo sapiens) (aka membrane spanning 4-domains a8)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and characterisation of the Sry-related transcription factor gene Sox8.
', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sox8 (xenopus laevis) (aka sry-box 8 l homeolog)
B: sox8 (gallus gallus) (aka sry-box 8)
C: sox10 multiple-species conserved sequence 8 (mus musculus) (aka sox10 multiple-species conserved sequence 8)
D: sox8 (homo sapiens) (aka sry-box transcription factor 8)
E: sox8 (mus musculus) (aka sry (sex determining region y)-box 8)
F: None of the above. | D |
<Instruct>: Given the context 'We report here the isolation of Sox8 and its characterisation in mice and humans.', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sry-box transcription factor 8 (homo sapiens) (aka sry-box transcription factor 8)
B: sox8 (xenopus tropicalis) (aka sry-box 8)
C: sox8 (xenopus laevis) (aka sry-box 8 l homeolog)
D: sox8 (gallus gallus) (aka sry-box 8)
E: sox10 multiple-species conserved sequence 8 (mus musculus) (aka sox10 multiple-species conserved sequence 8)
F: None of the above. | A |
<Instruct>: Given the context 'This gene has a remarkably similar primary structure and genomic organisation to the campomelic dysplasia gene SOX9 and the Waardenburg-Shah syndrome gene SOX10.', select the correct biomedical concept corresponding to 'sox9'. Answer using one of the provided options. | <Options>: A: sox9 (gallus gallus) (aka sry-box 9)
B: sox9 (homo sapiens) (aka sry-box transcription factor 9)
C: sox9 promoter region (homo sapiens) (aka sox9 promoter region)
D: sox9-b (xenopus laevis) (sry-box 9 s homeolog (xenopus laevis)) (aka sry-box 9 s homeolog)
E: sox9 (xenopus laevis) (sry-box 9 l homeolog (xenopus laevis)) (aka sry-box 9 l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'This gene has a remarkably similar primary structure and genomic organisation to the campomelic dysplasia gene SOX9 and the Waardenburg-Shah syndrome gene SOX10.', select the correct biomedical concept corresponding to 'sox10'. Answer using one of the provided options. | <Options>: A: sox10 (xenopus laevis) (aka sry-box 10 l homeolog)
B: sox-10 (homo sapiens) (aka sry-box transcription factor 10)
C: sox-10 (gallus gallus) (aka sry-box 10)
D: sox10 (danio rerio) (aka sry-box transcription factor 10)
E: sox10 (xenopus tropicalis) (aka sry-box 10)
F: None of the above. | B |
<Instruct>: Given the context 'SOX8 protein is able to bind to canonical SOX target DNA sequences and activate transcription in vitro through two separate trans -activation regions.', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sry-box transcription factor 8 (homo sapiens) (aka sry-box transcription factor 8)
B: sox8 (sus scrofa) (aka sry-box transcription factor 8)
C: sox8 (xenopus tropicalis) (aka sry-box 8)
D: sry-box 8 (gallus gallus) (aka sry-box 8)
E: sox8 (mus musculus) (aka sry (sex determining region y)-box 8)
F: None of the above. | A |
<Instruct>: Given the context 'SOX8 protein is able to bind to canonical SOX target DNA sequences and activate transcription in vitro through two separate trans -activation regions.', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sox8 (mus musculus) (aka sry (sex determining region y)-box 8)
B: sox8 (gallus gallus) (aka sry-box 8)
C: sox8 (danio rerio) (aka sry-box transcription factor 8b)
D: sox8 (sus scrofa) (aka sry-box transcription factor 8)
E: sox8 (xenopus tropicalis) (aka sry-box 8)
F: None of the above. | F |
<Instruct>: Given the context 'Further, Sox8 is expressed in the central nervous system, limbs, kidneys, gonads and craniofacial structures during mouse embryo development.', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sox8 (danio rerio) (aka sry-box transcription factor 8b)
B: sry-box 8 (gallus gallus) (aka sry-box 8)
C: sox8 (homo sapiens) (aka sry-box transcription factor 8)
D: sox10 multiple-species conserved sequence 8 (mus musculus) (aka sox10 multiple-species conserved sequence 8)
E: sox8 (xenopus tropicalis) (aka sry-box 8)
F: None of the above. | C |
<Instruct>: Given the context 'Sox8 maps to the t complex on mouse chromosome 17 and to human chromosome 16p13.3, a region associated with the microphthalmia-cataract syndrome CATM and the alpha-thalassemia/mental retardation syndrome ATR-16.', select the correct biomedical concept corresponding to 'sox8'. Answer using one of the provided options. | <Options>: A: sox8 (mus musculus) (aka sry (sex determining region y)-box 8)
B: sox8 (danio rerio) (aka sry-box transcription factor 8b)
C: sry-box transcription factor 8 (homo sapiens) (aka sry-box transcription factor 8)
D: sox8 (gallus gallus) (aka sry-box 8)
E: sox10 multiple-species conserved sequence 8 (mus musculus) (aka sox10 multiple-species conserved sequence 8)
F: None of the above. | C |
<Instruct>: Given the context 'Syntaphilin: a syntaxin-1 clamp that controls SNARE assembly.
', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (homo sapiens) (aka syntaphilin)
B: syntaphilin s homeolog (xenopus laevis) (aka syntaphilin s homeolog)
C: syntaphilin (xenopus tropicalis) (aka syntaphilin)
D: syn (drosophila melanogaster) (synapsin (drosophila melanogaster)) (aka synapsin)
E: syn1 (drosophila melanogaster) (syntrophin-like 1 (drosophila melanogaster)) (aka syntrophin-like 1)
F: None of the above. | A |
<Instruct>: Given the context 'Syntaxin-1 is a key component of the synaptic vesicle docking/fusion machinery that forms the SNARE complex with VAMP/synaptobrevin and SNAP-25.', select the correct biomedical concept corresponding to 'snap-25'. Answer using one of the provided options. | <Options>: A: snap25 (sus scrofa) (aka synaptosome associated protein 25)
B: snap-25 (xenopus laevis) (synaptosome associated protein 25kda s homeolog (xenopus laevis)) (aka synaptosome associated protein 25kda s homeolog)
C: snap-25 (mus musculus) (aka synaptosomal-associated protein 25)
D: snap25 (drosophila melanogaster) (aka synaptosomal-associated protein 25kda)
E: synaptosome associated protein 25 (homo sapiens) (aka synaptosome associated protein 25)
F: None of the above. | E |
<Instruct>: Given the context 'We have cloned and characterized a protein called syntaphilin that is selectively expressed in brain.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (bos taurus) (aka syntaphilin)
B: syntaphilin (sus scrofa) (aka syntaphilin)
C: syntaphilin (homo sapiens) (aka syntaphilin)
D: syn1 (drosophila melanogaster) (synapsin (drosophila melanogaster)) (aka synapsin)
E: syntaphilin (xenopus tropicalis) (aka syntaphilin)
F: None of the above. | C |
<Instruct>: Given the context 'Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits SNARE complex formation by absorbing free syntaxin-1.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (xenopus tropicalis) (aka syntaphilin)
B: syn1 (drosophila melanogaster) (syntrophin-like 1 (drosophila melanogaster)) (aka syntrophin-like 1)
C: syntaphilin (homo sapiens) (aka syntaphilin)
D: syntaphilin (bos taurus) (aka syntaphilin)
E: syntaphilin (xenopus laevis) (aka syntaphilin l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits SNARE complex formation by absorbing free syntaxin-1.', select the correct biomedical concept corresponding to 'snap-25'. Answer using one of the provided options. | <Options>: A: synaptosome associated protein 25 (homo sapiens) (aka synaptosome associated protein 25)
B: snap-25 (xenopus laevis) (synaptosome associated protein 25kda s homeolog (xenopus laevis)) (aka synaptosome associated protein 25kda s homeolog)
C: snap25 (sus scrofa) (aka synaptosome associated protein 25)
D: snap-25 (bos taurus) (aka synaptosome associated protein 25)
E: snap-25 (mus musculus) (aka synaptosomal-associated protein 25)
F: None of the above. | A |
<Instruct>: Given the context 'Transient overexpression of syntaphilin in cultured hippocampal neurons significantly reduces neurotransmitter release.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (bos taurus) (aka syntaphilin)
B: syntaphilin s homeolog (xenopus laevis) (aka syntaphilin s homeolog)
C: syntaphilin (xenopus tropicalis) (aka syntaphilin)
D: syntaphilin (homo sapiens) (aka syntaphilin)
E: syn1 (drosophila melanogaster) (syntrophin-like 1 (drosophila melanogaster)) (aka syntrophin-like 1)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, introduction of syntaphilin into presynaptic superior cervical ganglion neurons in culture inhibits synaptic transmission.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (homo sapiens) (aka syntaphilin)
B: syntaphilin s homeolog (xenopus laevis) (aka syntaphilin s homeolog)
C: syntaphilin (rattus norvegicus) (aka syntaphilin)
D: syntaphilin (xenopus laevis) (aka syntaphilin l homeolog)
E: syn1 (drosophila melanogaster) (syntrophin-like 1 (drosophila melanogaster)) (aka syntrophin-like 1)
F: None of the above. | A |
<Instruct>: Given the context 'These findings suggest that syntaphilin may function as a molecular clamp that controls free syntaxin-1 availability for the assembly of the SNARE complex, and thereby regulates synaptic vesicle exocytosis.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (xenopus laevis) (aka syntaphilin l homeolog)
B: syn1 (drosophila melanogaster) (synapsin (drosophila melanogaster)) (aka synapsin)
C: syntaphilin (rattus norvegicus) (aka syntaphilin)
D: syntaphilin (homo sapiens) (aka syntaphilin)
E: syntaphilin (bos taurus) (aka syntaphilin)
F: None of the above. | D |
<Instruct>: Given the context 'These findings suggest that syntaphilin may function as a molecular clamp that controls free syntaxin-1 availability for the assembly of the SNARE complex, and thereby regulates synaptic vesicle exocytosis.', select the correct biomedical concept corresponding to 'syntaphilin'. Answer using one of the provided options. | <Options>: A: syntaphilin (bos taurus) (aka syntaphilin)
B: syntaphilin s homeolog (xenopus laevis) (aka syntaphilin s homeolog)
C: syntaphilin (sus scrofa) (aka syntaphilin)
D: syn1 (drosophila melanogaster) (syntrophin-like 1 (drosophila melanogaster)) (aka syntrophin-like 1)
E: syntaphilin (rattus norvegicus) (aka syntaphilin)
F: None of the above. | F |
<Instruct>: Given the context 'Human follicle stimulating hormone receptor variants lacking transmembrane domains display altered post-translational conformations.
', select the correct biomedical concept corresponding to 'human follicle stimulating hormone receptor'. Answer using one of the provided options. | <Options>: A: thyroid stimulating hormone receptor (homo sapiens) (aka thyroid stimulating hormone receptor)
B: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
C: follicle stimulating hormone receptor (xenopus tropicalis) (aka follicle stimulating hormone receptor)
D: fshr (homo sapiens) (aka follicle stimulating hormone receptor)
E: follicle stimulating hormone receptor (gallus gallus) (aka follicle stimulating hormone receptor)
F: None of the above. | D |
<Instruct>: Given the context 'To determine receptor variant trafficking and intracellular processing in mammalian cells, the intracellular fate of intentionally truncated variants of human follicle stimulating hormone receptor (hFSH-R) expressed in CHO cells was examined.', select the correct biomedical concept corresponding to 'follicle stimulating hormone receptor'. Answer using one of the provided options. | <Options>: A: follicle stimulating hormone receptor (bos taurus) (aka follicle stimulating hormone receptor)
B: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
C: follicle stimulating hormone receptor (mus musculus) (aka follicle stimulating hormone receptor)
D: follicle stimulating hormone receptor (xenopus tropicalis) (aka follicle stimulating hormone receptor)
E: fshr (sus scrofa) (aka follicle stimulating hormone receptor)
F: None of the above. | B |
<Instruct>: Given the context 'To determine receptor variant trafficking and intracellular processing in mammalian cells, the intracellular fate of intentionally truncated variants of human follicle stimulating hormone receptor (hFSH-R) expressed in CHO cells was examined.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: ghsr (homo sapiens) (aka growth hormone secretagogue receptor)
B: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
C: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
D: fshr (homo sapiens) (aka follicle stimulating hormone receptor)
E: ghr (homo sapiens) (aka growth hormone receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Epitope mapping using synthetic peptides, and truncated hFSH-R variants revealed that mAb 106.156 bound to ECD residues 183-220, while mAbs 106.318, 106.290, 106.263 bound ECD residues 300-331.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: ghr (homo sapiens) (aka growth hormone receptor)
B: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
C: ghrhr (homo sapiens) (aka growth hormone releasing hormone receptor)
D: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
E: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Immunofluorescence microscopy showed that mAbs 106.318 and 106.156 stained the surface of fixed, intact CHO cells expressing wild type hFSH-R. However, following cell permeabilization all four antibodies stained hFSH-R in Golgi and endoplasmic reticulum.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
B: ghsr (homo sapiens) (aka growth hormone secretagogue receptor)
C: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
D: ghr (homo sapiens) (aka growth hormone receptor)
E: growth hormone releasing hormone receptor (homo sapiens) (aka growth hormone releasing hormone receptor)
F: None of the above. | C |
<Instruct>: Given the context 'Immunofluorescence microscopy showed that mAbs 106.318 and 106.156 stained the surface of fixed, intact CHO cells expressing wild type hFSH-R. However, following cell permeabilization all four antibodies stained hFSH-R in Golgi and endoplasmic reticulum.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
B: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
C: ghr (homo sapiens) (aka growth hormone receptor)
D: thyroid stimulating hormone receptor (homo sapiens) (aka thyroid stimulating hormone receptor)
E: ghsr (homo sapiens) (aka growth hormone secretagogue receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Both glycosylated truncated hFSH-R variants were sensitive to peptide-N-glycanase F and endoglycosidase H but insensitive to neuraminidase indicating that these variants possess high mannose type oligosaccharides.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: ghr (homo sapiens) (aka growth hormone receptor)
B: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
C: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
D: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
E: ghsr (homo sapiens) (aka growth hormone secretagogue receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Both glycosylated truncated hFSH-R variants were sensitive to peptide-N-glycanase F and endoglycosidase H but insensitive to neuraminidase indicating that these variants possess high mannose type oligosaccharides.', select the correct biomedical concept corresponding to 'neuraminidase'. Answer using one of the provided options. | <Options>: A: neuraminidase 1 (homo sapiens) (aka neuraminidase 1)
B: sialic acid acetylesterase (homo sapiens) (aka sialic acid acetylesterase)
C: neuraminidase 1 (sus scrofa) (aka neuraminidase 1)
D: neuraminidase 3 (homo sapiens) (aka neuraminidase 3)
E: neuraminidase 4 (homo sapiens) (aka neuraminidase 4)
F: None of the above. | A |
<Instruct>: Given the context 'Thus truncated hFSH-R variants do not reach the medial or trans Golgi where high mannose oligosaccharides are trimmed and sialic acid is added.', select the correct biomedical concept corresponding to 'hfsh-r'. Answer using one of the provided options. | <Options>: A: ghsr (homo sapiens) (aka growth hormone secretagogue receptor)
B: follicle stimulating hormone receptor (homo sapiens) (aka follicle stimulating hormone receptor)
C: gonadotropin releasing hormone receptor (homo sapiens) (aka gonadotropin releasing hormone receptor)
D: tshr (homo sapiens) (aka thyroid stimulating hormone receptor)
E: growth hormone releasing hormone receptor (homo sapiens) (aka growth hormone releasing hormone receptor)
F: None of the above. | B |
<Instruct>: Given the context 'The pro-alpha3(V) collagen chain.', select the correct biomedical concept corresponding to 'pro-alpha3(v) collagen'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
B: collagen type v alpha 3 chain (sus scrofa) (aka collagen type v alpha 3 chain)
C: collagen type v alpha 3 chain (homo sapiens) (aka collagen type v alpha 3 chain)
D: collagen type v alpha 3 chain (xenopus tropicalis) (aka collagen type v alpha 3 chain)
E: collagen type v alpha 3 chain (bos taurus) (aka collagen type v alpha 3 chain)
F: None of the above. | C |
<Instruct>: Given the context 'The pro-alpha3(V) collagen chain.', select the correct biomedical concept corresponding to 'pro-alpha3(v) collagen'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 3 chain (rattus norvegicus) (aka collagen type v alpha 3 chain)
B: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
C: collagen type v alpha 3 chain (xenopus tropicalis) (aka collagen type v alpha 3 chain)
D: collagen type v alpha 3 chain (sus scrofa) (aka collagen type v alpha 3 chain)
E: collagen type v alpha 3 chain (bos taurus) (aka collagen type v alpha 3 chain)
F: None of the above. | F |
<Instruct>: Given the context 'The low abundance fibrillar collagen type V is widely distributed in tissues as an alpha1(V)(2)alpha2(V) heterotrimer that helps regulate the diameters of fibrils of the abundant collagen type I. Mutations in the alpha1(V) and alpha2(V) chain genes have been identified in some cases of classical Ehlers-Danlos syndrome (EDS), in which aberrant collagen fibrils are associated with connective tissue fragility, particularly in skin and joints.', select the correct biomedical concept corresponding to 'alpha1(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 1 chain (rattus norvegicus) (aka collagen type v alpha 1 chain)
B: vla5a (homo sapiens) (aka integrin subunit alpha 5)
C: collagen type v alpha 1 chain (sus scrofa) (aka collagen type v alpha 1 chain)
D: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
E: collagen type xv alpha 1 chain (homo sapiens) (aka collagen type xv alpha 1 chain)
F: None of the above. | D |
<Instruct>: Given the context 'The low abundance fibrillar collagen type V is widely distributed in tissues as an alpha1(V)(2)alpha2(V) heterotrimer that helps regulate the diameters of fibrils of the abundant collagen type I. Mutations in the alpha1(V) and alpha2(V) chain genes have been identified in some cases of classical Ehlers-Danlos syndrome (EDS), in which aberrant collagen fibrils are associated with connective tissue fragility, particularly in skin and joints.', select the correct biomedical concept corresponding to 'alpha2(v)'. Answer using one of the provided options. | <Options>: A: vla5a (homo sapiens) (aka integrin subunit alpha 5)
B: collagen type v alpha 2 chain (homo sapiens) (aka collagen type v alpha 2 chain)
C: collagen type v alpha 2 chain (gallus gallus) (aka collagen type v alpha 2 chain)
D: collagen type v alpha 2 chain (rattus norvegicus) (aka collagen type v alpha 2 chain)
E: vlaa2 (homo sapiens) (aka integrin subunit alpha 2)
F: None of the above. | B |
<Instruct>: Given the context 'The low abundance fibrillar collagen type V is widely distributed in tissues as an alpha1(V)(2)alpha2(V) heterotrimer that helps regulate the diameters of fibrils of the abundant collagen type I. Mutations in the alpha1(V) and alpha2(V) chain genes have been identified in some cases of classical Ehlers-Danlos syndrome (EDS), in which aberrant collagen fibrils are associated with connective tissue fragility, particularly in skin and joints.', select the correct biomedical concept corresponding to 'alpha1(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
B: integrin subunit alpha v (rattus norvegicus) (aka integrin subunit alpha v)
C: collagen type xiv alpha 1 chain (homo sapiens) (aka collagen type xiv alpha 1 chain)
D: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
E: alpha1 (homo sapiens) (aka adrenoceptor alpha 1d)
F: None of the above. | A |
<Instruct>: Given the context 'The low abundance fibrillar collagen type V is widely distributed in tissues as an alpha1(V)(2)alpha2(V) heterotrimer that helps regulate the diameters of fibrils of the abundant collagen type I. Mutations in the alpha1(V) and alpha2(V) chain genes have been identified in some cases of classical Ehlers-Danlos syndrome (EDS), in which aberrant collagen fibrils are associated with connective tissue fragility, particularly in skin and joints.', select the correct biomedical concept corresponding to 'alpha2(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 2 chain (homo sapiens) (aka collagen type v alpha 2 chain)
B: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
C: collagen type v alpha 2 chain (sus scrofa) (aka collagen type v alpha 2 chain)
D: collagen type v alpha 2 chain (gallus gallus) (aka collagen type v alpha 2 chain)
E: collagen type v alpha 2 chain (rattus norvegicus) (aka collagen type v alpha 2 chain)
F: None of the above. | A |
<Instruct>: Given the context 'Type V collagen also exists as an alpha1(V)alpha2(V)alpha3(V) heterotrimer that has remained poorly characterized chiefly due to inability to obtain the complete primary structure or nucleic acid probes for the alpha3(V) chain or its biosynthetic precursor, pro-alpha3(V).', select the correct biomedical concept corresponding to 'alpha1(v)'. Answer using one of the provided options. | <Options>: A: collagen type xv alpha 1 chain (homo sapiens) (aka collagen type xv alpha 1 chain)
B: collagen type xxv alpha 1 chain (homo sapiens) (aka collagen type xxv alpha 1 chain)
C: vla5a (homo sapiens) (aka integrin subunit alpha 5)
D: integrin subunit alpha v (rattus norvegicus) (aka integrin subunit alpha v)
E: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
F: None of the above. | E |
<Instruct>: Given the context 'Type V collagen also exists as an alpha1(V)alpha2(V)alpha3(V) heterotrimer that has remained poorly characterized chiefly due to inability to obtain the complete primary structure or nucleic acid probes for the alpha3(V) chain or its biosynthetic precursor, pro-alpha3(V).', select the correct biomedical concept corresponding to 'alpha2(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 2 chain (sus scrofa) (aka collagen type v alpha 2 chain)
B: vla5a (homo sapiens) (aka integrin subunit alpha 5)
C: collagen type v alpha 2 chain (gallus gallus) (aka collagen type v alpha 2 chain)
D: collagen type v alpha 2 chain (homo sapiens) (aka collagen type v alpha 2 chain)
E: collagen type v alpha 2 chain (rattus norvegicus) (aka collagen type v alpha 2 chain)
F: None of the above. | D |
<Instruct>: Given the context 'Type V collagen also exists as an alpha1(V)alpha2(V)alpha3(V) heterotrimer that has remained poorly characterized chiefly due to inability to obtain the complete primary structure or nucleic acid probes for the alpha3(V) chain or its biosynthetic precursor, pro-alpha3(V).', select the correct biomedical concept corresponding to 'alpha3(v)'. Answer using one of the provided options. | <Options>: A: collagen type vi alpha 3 chain (homo sapiens) (aka collagen type vi alpha 3 chain)
B: collagen type v alpha 3 chain (homo sapiens) (aka collagen type v alpha 3 chain)
C: collagen type v alpha 3 chain (rattus norvegicus) (aka collagen type v alpha 3 chain)
D: collagen type v alpha 3 chain (sus scrofa) (aka collagen type v alpha 3 chain)
E: vla3a (homo sapiens) (aka integrin subunit alpha 3)
F: None of the above. | B |
<Instruct>: Given the context 'Type V collagen also exists as an alpha1(V)alpha2(V)alpha3(V) heterotrimer that has remained poorly characterized chiefly due to inability to obtain the complete primary structure or nucleic acid probes for the alpha3(V) chain or its biosynthetic precursor, pro-alpha3(V).', select the correct biomedical concept corresponding to 'alpha3(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 3 chain (homo sapiens) (aka collagen type v alpha 3 chain)
B: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
C: collagen type vi alpha 3 chain (homo sapiens) (aka collagen type vi alpha 3 chain)
D: vla3a (homo sapiens) (aka integrin subunit alpha 3)
E: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
F: None of the above. | A |
<Instruct>: Given the context 'Type V collagen also exists as an alpha1(V)alpha2(V)alpha3(V) heterotrimer that has remained poorly characterized chiefly due to inability to obtain the complete primary structure or nucleic acid probes for the alpha3(V) chain or its biosynthetic precursor, pro-alpha3(V).', select the correct biomedical concept corresponding to 'pro-alpha3(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 3 chain (rattus norvegicus) (aka collagen type v alpha 3 chain)
B: collagen, type v, alpha 1 (xenopus tropicalis) (aka collagen, type v, alpha 1)
C: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
D: collagen type v alpha 3 chain (xenopus tropicalis) (aka collagen type v alpha 3 chain)
E: collagen type v alpha 3 chain (homo sapiens) (aka collagen type v alpha 3 chain)
F: None of the above. | E |
<Instruct>: Given the context 'Pro-alpha3(V) is shown to be closely related to the alpha1(V) precursor, pro-alpha1(V), but with marked differences in N-propeptide sequences, and collagenous domain features that provide insights into the low melting temperature of alpha1(V)alpha2(V)alpha3(V)', select the correct biomedical concept corresponding to 'pro-alpha3(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 3 chain (xenopus tropicalis) (aka collagen type v alpha 3 chain)
B: collagen type v alpha 3 chain (sus scrofa) (aka collagen type v alpha 3 chain)
C: apoa-v (xenopus tropicalis) (aka apolipoprotein a5)
D: collagen type v alpha 3 chain (homo sapiens) (aka collagen type v alpha 3 chain)
E: collagen, type v, alpha 1 s homeolog (xenopus laevis) (aka collagen, type v, alpha 1 s homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Pro-alpha3(V) is shown to be closely related to the alpha1(V) precursor, pro-alpha1(V), but with marked differences in N-propeptide sequences, and collagenous domain features that provide insights into the low melting temperature of alpha1(V)alpha2(V)alpha3(V)', select the correct biomedical concept corresponding to 'pro-alpha3(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 3 chain (sus scrofa) (aka collagen type v alpha 3 chain)
B: collagen type v alpha 3 s homeolog (xenopus laevis) (aka collagen type v alpha 3 s homeolog)
C: collagen, type v, alpha 1 s homeolog (xenopus laevis) (aka collagen, type v, alpha 1 s homeolog)
D: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
E: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
F: None of the above. | F |
<Instruct>: Given the context 'Pro-alpha3(V) is shown to be closely related to the alpha1(V) precursor, pro-alpha1(V), but with marked differences in N-propeptide sequences, and collagenous domain features that provide insights into the low melting temperature of alpha1(V)alpha2(V)alpha3(V)', select the correct biomedical concept corresponding to 'alpha1(v)'. Answer using one of the provided options. | <Options>: A: collagen type xv alpha 1 chain (homo sapiens) (aka collagen type xv alpha 1 chain)
B: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
C: integrin subunit alpha v (rattus norvegicus) (aka integrin subunit alpha v)
D: collagen type xxv alpha 1 chain (homo sapiens) (aka collagen type xxv alpha 1 chain)
E: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
F: None of the above. | B |
<Instruct>: Given the context 'Pro-alpha3(V) is shown to be closely related to the alpha1(V) precursor, pro-alpha1(V), but with marked differences in N-propeptide sequences, and collagenous domain features that provide insights into the low melting temperature of alpha1(V)alpha2(V)alpha3(V)', select the correct biomedical concept corresponding to 'pro-alpha1(v)'. Answer using one of the provided options. | <Options>: A: collagen type v alpha 1 chain (rattus norvegicus) (aka collagen type v alpha 1 chain)
B: collagen type v alpha 1 chain (homo sapiens) (aka collagen type v alpha 1 chain)
C: apoa-v (rattus norvegicus) (aka apolipoprotein a5)
D: collagen type v alpha 1 chain (sus scrofa) (aka collagen type v alpha 1 chain)
E: integrin subunit alpha v (homo sapiens) (aka integrin subunit alpha v)
F: None of the above. | B |
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