instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', select the correct biomedical concept corresponding to 'n-cadherin'. Answer using one of the provided options. | <Options>: A: cdhn (homo sapiens) (aka cadherin 2)
B: cadherin 1 (homo sapiens) (aka cadherin 1)
C: d-cad (drosophila melanogaster) (cadherin-n (drosophila melanogaster)) (aka cadherin-n)
D: cadherin 9 (homo sapiens) (aka cadherin 9)
E: neural-cadherin-like (gallus gallus) (aka neural-cadherin-like)
F: None of the above. | A |
<Instruct>: Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgki (homo sapiens) (aka diacylglycerol kinase iota)
B: dgsi (mus musculus) (aka ess-2 splicing factor)
C: dg1 (homo sapiens) (aka desmoglein 1)
D: dgi (mus musculus) (aka desmoglein 1 alpha)
E: dgic (homo sapiens) (aka placenta associated 8)
F: None of the above. | C |
<Instruct>: Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
B: dg1 (homo sapiens) (aka desmoglein 1)
C: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
D: dgic (homo sapiens) (aka placenta associated 8)
E: dgi (mus musculus) (aka desmoglein 1 alpha)
F: None of the above. | F |
<Instruct>: Given the context 'The highest degree of similarity between human N-cadherin and human DGI, and likewise between bovine DGI and human DGI, is greatest in the most amino-terminal extracellular domain.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgki (homo sapiens) (aka diacylglycerol kinase iota)
B: dgmii (drosophila melanogaster) (aka alpha-mannosidase class ii a)
C: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
D: dg1 (homo sapiens) (aka desmoglein 1)
E: dgi (mus musculus) (aka desmoglein 1 alpha)
F: None of the above. | D |
<Instruct>: Given the context 'The cytoplasmic portion of the molecule contains a cadherin-like region and, like bovine DGI, a carboxy-terminal tail that is not present in the cadherins, comprising three additional domains.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgi (mus musculus) (aka desmoglein 1 alpha)
B: dg1 (homo sapiens) (aka desmoglein 1)
C: dgki (homo sapiens) (aka diacylglycerol kinase iota)
D: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
E: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
F: None of the above. | F |
<Instruct>: Given the context 'One of these contains a novel repeating motif of 29 +/- 1 residues, first identified in bovine DGI.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgi (mus musculus) (aka desmoglein 1 alpha)
B: dgic (homo sapiens) (aka placenta associated 8)
C: dgdi (drosophila melanogaster) (aka gdp dissociation inhibitor)
D: dgsi (mus musculus) (aka ess-2 splicing factor)
E: dgki (homo sapiens) (aka diacylglycerol kinase iota)
F: None of the above. | F |
<Instruct>: Given the context 'Five amino acids that are identical in bovine and human DGI lie in the second of the two predicted beta-strands, and intriguingly contain putative target sites for protein kinase C.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgmii (drosophila melanogaster) (aka alpha-mannosidase class ii a)
B: dgki (homo sapiens) (aka diacylglycerol kinase iota)
C: dgi (mus musculus) (aka desmoglein 1 alpha)
D: dgsi (mus musculus) (aka ess-2 splicing factor)
E: dg1 (homo sapiens) (aka desmoglein 1)
F: None of the above. | E |
<Instruct>: Given the context 'Characterization of human loricrin.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin-like (homo sapiens) (aka loricrin-like)
B: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
C: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
D: loricrin (mus musculus) (aka loricrin cornified envelope precursor protein)
E: loricrin (homo sapiens) (aka loricrin cornified envelope precursor protein)
F: None of the above. | E |
<Instruct>: Given the context 'We have isolated and characterized a full-length cDNA clone encoding human loricrin.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin cornified envelope precursor protein (homo sapiens) (aka loricrin cornified envelope precursor protein)
B: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
C: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
D: loricrin-like (homo sapiens) (aka loricrin-like)
E: loricrin (sus scrofa) (aka loricrin cornified envelope precursor protein)
F: None of the above. | A |
<Instruct>: Given the context 'We have isolated and characterized a full-length cDNA clone encoding human loricrin.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin-like (xenopus tropicalis) (aka loricrin-like)
B: loricrin (mus musculus) (aka loricrin cornified envelope precursor protein)
C: loricrin (oryctolagus cuniculus) (aka loricrin cornified envelope precursor protein)
D: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
E: loricrin (xenopus tropicalis) (aka loricrin)
F: None of the above. | F |
<Instruct>: Given the context 'Curiously, this protein displays major differences from the recently described mouse loricrin (Mehrel, T., Hohl, D., Nakazawa, H., Rothnagel, J.A., Longley, M.A., Bundman, D., Cheng, C.K., Lichti, U., Bisher, M.E., Steven, A. C., Steinert, P.M., Yuspa, S.H., and Roop, D.R. (1990)', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
B: loricrin (xenopus tropicalis) (aka loricrin)
C: loricrin-like (homo sapiens) (aka loricrin-like)
D: loricrin (mus musculus) (aka loricrin cornified envelope precursor protein)
E: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, we have isolated four peptides from purified human cell envelopes that contain recognizable loricrin sequences and which are cross-linked by the N epsilon-(gamma-glutamyl)lysine isodipeptide bond.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
B: loricrin (mus musculus) (aka loricrin cornified envelope precursor protein)
C: loricrin (xenopus tropicalis) (aka loricrin)
D: loricrin-like (xenopus tropicalis) (aka loricrin-like)
E: loricrin (homo sapiens) (aka loricrin cornified envelope precursor protein)
F: None of the above. | E |
<Instruct>: Given the context 'The presence of such bonds thus affords an explanation for the extraordinary insolubility of loricrin by cross-linking to the cell envelope and can also explain the low steady-state levels of monomeric loricrin in cytoskeletal extracts of epidermis.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin (homo sapiens) (aka loricrin cornified envelope precursor protein)
B: loricrin (oryctolagus cuniculus) (aka loricrin cornified envelope precursor protein)
C: loricrin (mus musculus) (aka loricrin cornified envelope precursor protein)
D: loricrin-like (homo sapiens) (aka loricrin-like)
E: loricrin (sus scrofa) (aka loricrin cornified envelope precursor protein)
F: None of the above. | A |
<Instruct>: Given the context 'The presence of such bonds thus affords an explanation for the extraordinary insolubility of loricrin by cross-linking to the cell envelope and can also explain the low steady-state levels of monomeric loricrin in cytoskeletal extracts of epidermis.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin (homo sapiens) (aka loricrin cornified envelope precursor protein)
B: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
C: loricrin (sus scrofa) (aka loricrin cornified envelope precursor protein)
D: loricrin-like (xenopus tropicalis) (aka loricrin-like)
E: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
F: None of the above. | A |
<Instruct>: Given the context 'We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin cornified envelope precursor protein (homo sapiens) (aka loricrin cornified envelope precursor protein)
B: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
C: loricrin-like (homo sapiens) (aka loricrin-like)
D: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
E: loricrin (xenopus tropicalis) (aka loricrin)
F: None of the above. | A |
<Instruct>: Given the context 'We propose a model for the structure of loricrin in which (i) the unusual glycine-serine-rich sequences adopt a flexible loop conformation, indexed on the recurrent aliphatic residues; (ii) inter- or intramolecular isodipeptide and disulfide cross-links induce or stabilize folding of loricrin so as to form a more compact rosette-like structure; and (iii) the presence of the flexible glycine-rich loops necessarily will impact a flexible character to the cell envelope and entire epithelium.', select the correct biomedical concept corresponding to 'loricrin'. Answer using one of the provided options. | <Options>: A: loricrin (oryctolagus cuniculus) (aka loricrin cornified envelope precursor protein)
B: loricrin (rattus norvegicus) (aka loricrin cornified envelope precursor protein)
C: loricrin (bos taurus) (aka loricrin cornified envelope precursor protein)
D: loricrin-like (xenopus tropicalis) (aka loricrin-like)
E: loricrin cornified envelope precursor protein (homo sapiens) (aka loricrin cornified envelope precursor protein)
F: None of the above. | E |
<Instruct>: Given the context 'Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter.
', select the correct biomedical concept corresponding to 'cocaine- and antidepressant-sensitive human noradrenaline transporter'. Answer using one of the provided options. | <Options>: A: slc6a10 (homo sapiens) (aka solute carrier family 6 member 10, pseudogene)
B: slc6a9 (homo sapiens) (aka solute carrier family 6 member 9)
C: nact (homo sapiens) (solute carrier family 13 member 2 (homo sapiens)) (aka solute carrier family 13 member 2)
D: net1 (homo sapiens) (solute carrier family 6 member 5 (homo sapiens)) (aka solute carrier family 6 member 5)
E: net (homo sapiens) (solute carrier family 6 member 2 (homo sapiens)) (aka solute carrier family 6 member 2)
F: None of the above. | E |
<Instruct>: Given the context 'We have isolated a complementary DNA clone encoding a human noradrenaline transporter.', select the correct biomedical concept corresponding to 'noradrenaline transporter'. Answer using one of the provided options. | <Options>: A: slc6a2 (homo sapiens) (aka solute carrier family 6 member 2)
B: solute carrier family 1 member 2 (rattus norvegicus) (aka solute carrier family 1 member 2)
C: solute carrier family 11 member 2 (rattus norvegicus) (aka solute carrier family 11 member 2)
D: slc6a3 (rattus norvegicus) (aka solute carrier family 6 member 3)
E: slc1 (rattus norvegicus) (aka melanin-concentrating hormone receptor 1)
F: None of the above. | A |
<Instruct>: Given the context 'A set of 11 clones encoding putative GTP binding proteins highly homologous to the yeast YPT1/SEC4 gene products have been isolated from an MDCK cell cDNA library.', select the correct biomedical concept corresponding to 'ypt1'. Answer using one of the provided options. | <Options>: A: ypt1 (homo sapiens) (aka rab1a, member ras oncogene family)
B: ypt7 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt7)
C: tpt1 (xenopus laevis) (translationally-controlled tumor protein homolog (xenopus laevis)) (aka translationally-controlled tumor protein homolog)
D: ypt1 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt1)
E: pyt1 (saccharomyces cerevisiae s288c) (aka rim2p)
F: None of the above. | D |
<Instruct>: Given the context 'A set of 11 clones encoding putative GTP binding proteins highly homologous to the yeast YPT1/SEC4 gene products have been isolated from an MDCK cell cDNA library.', select the correct biomedical concept corresponding to 'sec4'. Answer using one of the provided options. | <Options>: A: sec4l (homo sapiens) (aka rab40b, member ras oncogene family)
B: exocyst complex component 4 (homo sapiens) (aka exocyst complex component 4)
C: sec14 (saccharomyces cerevisiae s288c) (aka phosphatidylinositol/phosphatidylcholine transfer protein sec14)
D: sec4 (saccharomyces cerevisiae s288c) (aka rab family gtpase sec4)
E: sec24 (saccharomyces cerevisiae s288c) (aka copii subunit sec24)
F: None of the above. | D |
<Instruct>: Given the context 'A set of 11 clones encoding putative GTP binding proteins highly homologous to the yeast YPT1/SEC4 gene products have been isolated from an MDCK cell cDNA library.', select the correct biomedical concept corresponding to 'sec4'. Answer using one of the provided options. | <Options>: A: sec24d (xenopus tropicalis) (sec24 homolog c, copii coat complex component (xenopus tropicalis)) (aka sec24 homolog c, copii coat complex component)
B: exo4 (homo sapiens) (aka synaptotagmin like 2)
C: sec6 (saccharomyces cerevisiae s288c) (aka snare-binding exocyst subunit sec6)
D: sec4l (homo sapiens) (aka rab40b, member ras oncogene family)
E: sec4 (candida albicans sc5314) (aka rab family gtpase)
F: None of the above. | F |
<Instruct>: Given the context 'One, the MDCK homolog of rab2, is associated with a structure having the characteristics of an intermediate compartment between the endoplasmic reticulum and the Golgi apparatus.', select the correct biomedical concept corresponding to 'rab2'. Answer using one of the provided options. | <Options>: A: rab2a, member ras oncogene family (homo sapiens) (aka rab2a, member ras oncogene family)
B: rab2 (drosophila melanogaster) (aka rab2)
C: rab, member of ras oncogene family like 2b (homo sapiens) (aka rab, member of ras oncogene family like 2b)
D: rab2l (homo sapiens) (aka ral guanine nucleotide dissociation stimulator like 2)
E: rab, member of ras oncogene family like 2a (homo sapiens) (aka rab, member of ras oncogene family like 2a)
F: None of the above. | A |
<Instruct>: Given the context 'The second, rab5, is located at the cytoplasmic surface of the plasma membrane and on early endosomes, while the third, rab7, is found on late endosomes.', select the correct biomedical concept corresponding to 'rab5'. Answer using one of the provided options. | <Options>: A: rab5 (drosophila melanogaster) (aka rab5)
B: rab5l (homo sapiens) (aka rab5c, member ras oncogene family)
C: rab5a (homo sapiens) (aka rab5a, member ras oncogene family)
D: rab5c, member ras oncogene family (rattus norvegicus) (aka rab5c, member ras oncogene family)
E: None of the above. | C |
<Instruct>: Given the context 'The second, rab5, is located at the cytoplasmic surface of the plasma membrane and on early endosomes, while the third, rab7, is found on late endosomes.', select the correct biomedical concept corresponding to 'rab7'. Answer using one of the provided options. | <Options>: A: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
B: rab7 (drosophila melanogaster) (aka rab7)
C: rab7 (homo sapiens) (rab7b, member ras oncogene family (homo sapiens)) (aka rab7b, member ras oncogene family)
D: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
E: rab7a (homo sapiens) (aka rab7a, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'These findings provide evidence that members of the YPT1/SEC4 subfamily of GTP binding proteins are localized to specific exocytic and endocytic subcompartments in mammalian cells.', select the correct biomedical concept corresponding to 'ypt1'. Answer using one of the provided options. | <Options>: A: ypt10 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt10)
B: ypt7 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt7)
C: ypt11 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt11)
D: ypt1 (saccharomyces cerevisiae s288c) (aka rab family gtpase ypt1)
E: ypt1 (candida albicans sc5314) (aka rab family gtpase)
F: None of the above. | D |
<Instruct>: Given the context 'These findings provide evidence that members of the YPT1/SEC4 subfamily of GTP binding proteins are localized to specific exocytic and endocytic subcompartments in mammalian cells.', select the correct biomedical concept corresponding to 'sec4'. Answer using one of the provided options. | <Options>: A: sec24d (xenopus tropicalis) (sec24 homolog c, copii coat complex component (xenopus tropicalis)) (aka sec24 homolog c, copii coat complex component)
B: rab family gtpase sec4 (saccharomyces cerevisiae s288c) (aka rab family gtpase sec4)
C: exo4 (homo sapiens) (aka synaptotagmin like 2)
D: sec24 (saccharomyces cerevisiae s288c) (aka copii subunit sec24)
E: sec4 (candida albicans sc5314) (aka rab family gtpase)
F: None of the above. | B |
<Instruct>: Given the context 'A human homologue of the yeast HDEL receptor.
', select the correct biomedical concept corresponding to 'hdel receptor'. Answer using one of the provided options. | <Options>: A: kdelr2 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 2)
B: kdel receptor (drosophila melanogaster) (aka kdel receptor)
C: kdelr3 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 3)
D: kdelr1 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 1)
E: edr (homo sapiens) (aka paternally expressed 10)
F: None of the above. | F |
<Instruct>: Given the context 'There is evidence that the ERD2 gene encodes the sorting receptor that recognizes HDEL in yeast; its product is an integral membrane protein of relative molecular mass 26,000 (26K) that is not glycosylated.', select the correct biomedical concept corresponding to 'erd2'. Answer using one of the provided options. | <Options>: A: erda2 (homo sapiens) (aka zinc finger protein 384)
B: erd2l3 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 3)
C: erd2.1 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 1)
D: erdj2 (homo sapiens) (aka sec63 protein translocation regulator)
E: dre2 (homo sapiens) (aka cytokine induced apoptosis inhibitor 1)
F: None of the above. | F |
<Instruct>: Given the context 'In contrast, Vaux et al. suggest that the mammalian KDEL receptor is a 72K glycoprotein that they detected using an anti-idiotypic antibody approach.', select the correct biomedical concept corresponding to 'kdel receptor'. Answer using one of the provided options. | <Options>: A: kdelr (drosophila melanogaster) (aka kdel receptor)
B: kdelr (xenopus tropicalis) (aka kdel endoplasmic reticulum protein retention receptor 3)
C: kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1 (mus musculus) (aka kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1)
D: kdelr1 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 1)
E: kdelr2 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 2)
F: None of the above. | D |
<Instruct>: Given the context 'We report here that human cells express a protein similar in sequence, size and properties to the ERD2 product, and propose that this protein is the human KDEL receptor.', select the correct biomedical concept corresponding to 'erd2'. Answer using one of the provided options. | <Options>: A: erdj2 (homo sapiens) (aka sec63 protein translocation regulator)
B: kdelr2 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 2)
C: erd2l3 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 3)
D: erd2 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 1)
E: erda2 (homo sapiens) (aka zinc finger protein 384)
F: None of the above. | D |
<Instruct>: Given the context 'We report here that human cells express a protein similar in sequence, size and properties to the ERD2 product, and propose that this protein is the human KDEL receptor.', select the correct biomedical concept corresponding to 'kdel receptor'. Answer using one of the provided options. | <Options>: A: kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1 (mus musculus) (aka kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1)
B: kdelr1 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 1)
C: kdelr (xenopus tropicalis) (aka kdel endoplasmic reticulum protein retention receptor 3)
D: kdelr3 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 3)
E: kdelr2 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 2)
F: None of the above. | B |
<Instruct>: Given the context 'We report here that human cells express a protein similar in sequence, size and properties to the ERD2 product, and propose that this protein is the human KDEL receptor.', select the correct biomedical concept corresponding to 'kdel receptor'. Answer using one of the provided options. | <Options>: A: kdelr (drosophila melanogaster) (aka kdel receptor)
B: kdelr3 (homo sapiens) (aka kdel endoplasmic reticulum protein retention receptor 3)
C: kdelr2 (danio rerio) (aka kdel endoplasmic reticulum protein retention receptor 2a)
D: kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1 (mus musculus) (aka kdel (lys-asp-glu-leu) endoplasmic reticulum protein retention receptor 1)
E: kdelr3 (danio rerio) (aka kdel endoplasmic reticulum protein retention receptor 3)
F: None of the above. | F |
<Instruct>: Given the context 'Primary structure and functional expression of rat and human stem cell factor DNAs.
', select the correct biomedical concept corresponding to 'stem cell factor'. Answer using one of the provided options. | <Options>: A: gmcsf (homo sapiens) (aka colony stimulating factor 2)
B: il-7 (homo sapiens) (interleukin 7 (homo sapiens)) (aka interleukin 7)
C: c-kit (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
D: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
E: kit ligand (homo sapiens) (aka kit ligand)
F: None of the above. | E |
<Instruct>: Given the context 'Partial cDNA and genomic clones of rat stem cell factor (SCF) have been isolated.', select the correct biomedical concept corresponding to 'stem cell factor'. Answer using one of the provided options. | <Options>: A: kit ligand (homo sapiens) (aka kit ligand)
B: interleukin 7 (homo sapiens) (aka interleukin 7)
C: gmcsf (homo sapiens) (aka colony stimulating factor 2)
D: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
E: c-kit (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
F: None of the above. | F |
<Instruct>: Given the context 'Partial cDNA and genomic clones of rat stem cell factor (SCF) have been isolated.', select the correct biomedical concept corresponding to 'scf'. Answer using one of the provided options. | <Options>: A: csf1 (homo sapiens) (aka colony stimulating factor 1)
B: scf (homo sapiens) (aka kit ligand)
C: csf3 (homo sapiens) (aka colony stimulating factor 3)
D: csf2 (homo sapiens) (aka colony stimulating factor 2)
E: None of the above. | E |
<Instruct>: Given the context 'Using probes based on the rat sequence, partial and full-length cDNA and genomic clones of human SCF have been isolated.', select the correct biomedical concept corresponding to 'scf'. Answer using one of the provided options. | <Options>: A: csf-1 (homo sapiens) (aka colony stimulating factor 1)
B: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
C: scf (homo sapiens) (aka kit ligand)
D: csf2 (homo sapiens) (aka colony stimulating factor 2)
E: None of the above. | C |
<Instruct>: Given the context 'SCF is able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow cultures.', select the correct biomedical concept corresponding to 'scf'. Answer using one of the provided options. | <Options>: A: kit ligand (homo sapiens) (aka kit ligand)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: csf3 (homo sapiens) (aka colony stimulating factor 3)
D: csf2 (homo sapiens) (aka colony stimulating factor 2)
E: None of the above. | A |
<Instruct>: Given the context 'SCF exhibits potent synergistic activities in conjunction with colony-stimulating factors, resulting in increased colony numbers and colony size.', select the correct biomedical concept corresponding to 'scf'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
B: sf (homo sapiens) (kit ligand (homo sapiens)) (aka kit ligand)
C: csf2 (homo sapiens) (aka colony stimulating factor 2)
D: csf1 (homo sapiens) (aka colony stimulating factor 1)
E: None of the above. | B |
<Instruct>: Given the context 'Autoantibodies to a novel nuclear Ag, Sp100, have recently been described that recognize a nuclear protein with an apparent molecular mass of 95 to 100 kDa and a dot-like distribution within cell nuclei.', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp100 nuclear antigen (homo sapiens) (aka sp100 nuclear antigen)
B: sp100 (bos taurus) (aka sp100 nuclear antigen)
C: sp100 (sus scrofa) (aka nuclear body protein sp140-like protein)
D: crsp100 (homo sapiens) (aka mediator complex subunit 24)
E: sp100 (drosophila melanogaster) (aka jonah 44e)
F: None of the above. | A |
<Instruct>: Given the context 'By immunoscreening of a lambda gt11 cDNA expression library derived from HeLa cells with an anti-Sp100 autoimmune serum a 0.7-kb cDNA (Sp26) coding for a fragment of Sp100 was isolated.', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp100 nuclear antigen (homo sapiens) (aka sp100 nuclear antigen)
B: sp140 (homo sapiens) (aka sp140 nuclear body protein)
C: sp100 (mus musculus) (aka nuclear antigen sp100)
D: sp100 (bos taurus) (aka sp100 nuclear antigen)
E: sp100 (sus scrofa) (aka nuclear body protein sp140-like protein)
F: None of the above. | A |
<Instruct>: Given the context 'By immunoscreening of a lambda gt11 cDNA expression library derived from HeLa cells with an anti-Sp100 autoimmune serum a 0.7-kb cDNA (Sp26) coding for a fragment of Sp100 was isolated.', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp100 (bos taurus) (aka sp100 nuclear antigen)
B: sp100 (mus musculus) (aka nuclear antigen sp100)
C: sp100 (sus scrofa) (aka nuclear body protein sp140-like protein)
D: sp100 nuclear antigen (homo sapiens) (aka sp100 nuclear antigen)
E: sp100-rs (mus musculus) (aka uncharacterized loc546065)
F: None of the above. | D |
<Instruct>: Given the context 'Expression of this cDNA and use of the recombinant protein in ELISA revealed that the fragment carries major Sp100 autoepitopes and that anti-Sp100 autoantibodies predominantly occur in patients suffering from primary biliary cirrhosis (50/184).', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp100 (drosophila melanogaster) (aka jonah 44e)
B: sp140 (homo sapiens) (aka sp140 nuclear body protein)
C: sp100 nuclear antigen (homo sapiens) (aka sp100 nuclear antigen)
D: sp100-rs (mus musculus) (aka uncharacterized loc546065)
E: sp100 (bos taurus) (aka sp100 nuclear antigen)
F: None of the above. | C |
<Instruct>: Given the context 'Expression of this cDNA and use of the recombinant protein in ELISA revealed that the fragment carries major Sp100 autoepitopes and that anti-Sp100 autoantibodies predominantly occur in patients suffering from primary biliary cirrhosis (50/184).', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp140 (homo sapiens) (aka sp140 nuclear body protein)
B: sp100 (drosophila melanogaster) (aka jonah 44e)
C: sp100-rs (mus musculus) (aka uncharacterized loc546065)
D: crsp100 (homo sapiens) (aka mediator complex subunit 24)
E: nuclear antigen sp100 (mus musculus) (aka nuclear antigen sp100)
F: None of the above. | F |
<Instruct>: Given the context 'Expression of this cDNA and use of the recombinant protein in ELISA revealed that the fragment carries major Sp100 autoepitopes and that anti-Sp100 autoantibodies predominantly occur in patients suffering from primary biliary cirrhosis (50/184).', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: crsp100 (homo sapiens) (aka mediator complex subunit 24)
B: sp140 (homo sapiens) (aka sp140 nuclear body protein)
C: sp100 (bos taurus) (aka sp100 nuclear antigen)
D: sp100 nuclear antigen (homo sapiens) (aka sp100 nuclear antigen)
E: sp100-rs (mus musculus) (aka uncharacterized loc546065)
F: None of the above. | D |
<Instruct>: Given the context 'The Sp100 autoantigen expressed in vitro from this cDNA and authenticated by a capture immunoblot assay, comigrated in SDS-PAGE with the authentic HeLa autoantigen of 95 to 100 kDa and thus showed an aberrant electrophoretic mobility.', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp140 (homo sapiens) (aka sp140 nuclear body protein)
B: sp100 (sus scrofa) (aka nuclear body protein sp140-like protein)
C: sp100-rs (mus musculus) (aka uncharacterized loc546065)
D: sp100 (homo sapiens) (aka sp100 nuclear antigen)
E: sp100 (mus musculus) (aka nuclear antigen sp100)
F: None of the above. | D |
<Instruct>: Given the context 'Computer based protein sequence analysis of the Sp100 autoantigen revealed regions of striking sequence similarities to the alpha 1 and alpha 2 domains of various human and non-human MHC class I Ag and to several transacting transcriptional regulatory proteins.', select the correct biomedical concept corresponding to 'sp100'. Answer using one of the provided options. | <Options>: A: sp100 (drosophila melanogaster) (aka jonah 44e)
B: sp100 (mus musculus) (aka nuclear antigen sp100)
C: sp100 (bos taurus) (aka sp100 nuclear antigen)
D: crsp100 (homo sapiens) (aka mediator complex subunit 24)
E: sp100 (homo sapiens) (aka sp100 nuclear antigen)
F: None of the above. | E |
<Instruct>: Given the context 'Although cell surface receptors for the Fc region of IgA (Fc alpha R) have been implicated in a variety of immune effector mechanisms, the molecular features of Fc alpha R remain only marginally characterized.', select the correct biomedical concept corresponding to 'fc alpha r'. Answer using one of the provided options. | <Options>: A: fcgr1a (homo sapiens) (aka fc gamma receptor ia)
B: fcgriiia (homo sapiens) (aka fc gamma receptor iiia)
C: fcamr (homo sapiens) (aka fc alpha and mu receptor)
D: fc alpha receptor (homo sapiens) (aka fc alpha receptor)
E: fcgr (homo sapiens) (aka fc gamma receptor iia)
F: None of the above. | D |
<Instruct>: Given the context 'Although cell surface receptors for the Fc region of IgA (Fc alpha R) have been implicated in a variety of immune effector mechanisms, the molecular features of Fc alpha R remain only marginally characterized.', select the correct biomedical concept corresponding to 'fc alpha r'. Answer using one of the provided options. | <Options>: A: fcgammariia (homo sapiens) (aka fc gamma receptor iia)
B: fcriiia (homo sapiens) (aka fc gamma receptor iiia)
C: fcamr (homo sapiens) (aka fc alpha and mu receptor)
D: fcgr1a (homo sapiens) (aka fc gamma receptor ia)
E: fcalphari (homo sapiens) (aka fc alpha receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Databank searches indicate that the human myeloid cell Fc alpha R sequence is unique, is a member of the immunoglobulin gene superfamily, and is related to Fc receptors for IgG (Fc gamma RI, II, and III) and IgE (Fc epsilon RI).', select the correct biomedical concept corresponding to 'fc alpha r'. Answer using one of the provided options. | <Options>: A: fcgr (homo sapiens) (aka fc gamma receptor iia)
B: fcamr (homo sapiens) (aka fc alpha and mu receptor)
C: fc alpha receptor (homo sapiens) (aka fc alpha receptor)
D: fcgr1a (homo sapiens) (aka fc gamma receptor ia)
E: fcgriiia (homo sapiens) (aka fc gamma receptor iiia)
F: None of the above. | C |
<Instruct>: Given the context 'Databank searches indicate that the human myeloid cell Fc alpha R sequence is unique, is a member of the immunoglobulin gene superfamily, and is related to Fc receptors for IgG (Fc gamma RI, II, and III) and IgE (Fc epsilon RI).', select the correct biomedical concept corresponding to 'fc epsilon ri'. Answer using one of the provided options. | <Options>: A: fcalphari (homo sapiens) (aka fc alpha receptor)
B: fc epsilon receptor ia (rattus norvegicus) (aka fc epsilon receptor ia)
C: fc epsilon receptor ig (homo sapiens) (aka fc epsilon receptor ig)
D: fc epsilon receptor ia (homo sapiens) (aka fc epsilon receptor ia)
E: fcgammariia (homo sapiens) (aka fc gamma receptor iia)
F: None of the above. | D |
<Instruct>: Given the context 'Molecular cloning and sequence analysis of cDNA encoding human ferrochelatase.
', select the correct biomedical concept corresponding to 'ferrochelatase'. Answer using one of the provided options. | <Options>: A: ferrochelatase (bos taurus) (aka ferrochelatase)
B: ferrochelatase (caenorhabditis elegans) (aka ferrochelatase)
C: ferrochelatase (escherichia coli str. k-12 substr. mg1655) (aka ferrochelatase)
D: ferrochelatase (oryctolagus cuniculus) (aka ferrochelatase)
E: ferrochelatase (homo sapiens) (aka ferrochelatase)
F: None of the above. | E |
<Instruct>: Given the context 'The cDNA encoding human ferrochelatase', select the correct biomedical concept corresponding to 'ferrochelatase'. Answer using one of the provided options. | <Options>: A: ferrochelatase (bos taurus) (aka ferrochelatase)
B: ferrochelatase (oryctolagus cuniculus) (aka ferrochelatase)
C: ferrochelatase (homo sapiens) (aka ferrochelatase)
D: ferrochelatase (escherichia coli str. k-12 substr. mg1655) (aka ferrochelatase)
E: ferrochelatase (danio rerio) (aka ferrochelatase)
F: None of the above. | C |
<Instruct>: Given the context '[EC 4.99.1.1] was isolated from a human placenta cDNA library in bacteriophage lambda gt11 by screening with a radiolabeled fragment of mouse ferrochelatase cDNA.', select the correct biomedical concept corresponding to 'ec 4.99.1.1'. Answer using one of the provided options. | <Options>: A: dj994e9.4 (homo sapiens) (aka olfactory receptor family 2 subfamily h member 1)
B: cgi-99 (homo sapiens) (aka rna transcription, translation and transport factor)
C: eca4 (homo sapiens) (aka gamma-aminobutyric acid type a receptor subunit alpha1)
D: ec97 (homo sapiens) (aka vps35 endosomal protein sorting factor like)
E: family with sequence similarity 99 member a (homo sapiens) (aka family with sequence similarity 99 member a)
F: None of the above. | F |
<Instruct>: Given the context '[EC 4.99.1.1] was isolated from a human placenta cDNA library in bacteriophage lambda gt11 by screening with a radiolabeled fragment of mouse ferrochelatase cDNA.', select the correct biomedical concept corresponding to 'ec 4.99.1.1'. Answer using one of the provided options. | <Options>: A: dj994e9.2 (homo sapiens) (aka mas1 proto-oncogene like, g protein-coupled receptor)
B: cgi-99 (homo sapiens) (aka rna transcription, translation and transport factor)
C: dj994e9.3 (homo sapiens) (aka ubiquitin d pseudogene 1)
D: eca4 (homo sapiens) (aka gamma-aminobutyric acid type a receptor subunit alpha1)
E: dj994e9.6 (homo sapiens) (aka olfactory receptor family 11 subfamily a member 1)
F: None of the above. | F |
<Instruct>: Given the context '[EC 4.99.1.1] was isolated from a human placenta cDNA library in bacteriophage lambda gt11 by screening with a radiolabeled fragment of mouse ferrochelatase cDNA.', select the correct biomedical concept corresponding to 'ferrochelatase'. Answer using one of the provided options. | <Options>: A: ferrochelatase (bos taurus) (aka ferrochelatase)
B: ferrochelatase (gallus gallus) (aka ferrochelatase)
C: ferrochelatase (danio rerio) (aka ferrochelatase)
D: ferrochelatase (caenorhabditis elegans) (aka ferrochelatase)
E: ferrochelatase (xenopus tropicalis) (aka ferrochelatase)
F: None of the above. | F |
<Instruct>: Given the context 'Northern blot analysis showed two mRNAs of about 2500 and 1600 bp for ferrochelatase in K562 and HepG2 cells.', select the correct biomedical concept corresponding to 'ferrochelatase'. Answer using one of the provided options. | <Options>: A: ferrochelatase (gallus gallus) (aka ferrochelatase)
B: ferrochelatase (homo sapiens) (aka ferrochelatase)
C: ferrochelatase (drosophila melanogaster) (aka ferrochelatase)
D: ferrochelatase (danio rerio) (aka ferrochelatase)
E: ferrochelatase-like (caenorhabditis elegans) (aka ferrochelatase-like)
F: None of the above. | B |
<Instruct>: Given the context 'As full-length cDNA for human ferrochelatase is now available, molecular lesions related to erythropoietic protoporphyria can be characterized.', select the correct biomedical concept corresponding to 'ferrochelatase'. Answer using one of the provided options. | <Options>: A: ferrochelatase (bos taurus) (aka ferrochelatase)
B: ferrochelatase (drosophila melanogaster) (aka ferrochelatase)
C: ferrochelatase (gallus gallus) (aka ferrochelatase)
D: ferrochelatase (homo sapiens) (aka ferrochelatase)
E: ferrochelatase (caenorhabditis elegans) (aka ferrochelatase)
F: None of the above. | D |
<Instruct>: Given the context 'Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.
', select the correct biomedical concept corresponding to 'pancreatic cholesterol esterase'. Answer using one of the provided options. | <Options>: A: pancreatic lipase (homo sapiens) (aka pancreatic lipase)
B: lipase e, hormone sensitive type (oryctolagus cuniculus) (aka lipase e, hormone sensitive type)
C: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
D: liver carboxylesterase (sus scrofa) (aka liver carboxylesterase)
E: lipase e, hormone sensitive type (homo sapiens) (aka lipase e, hormone sensitive type)
F: None of the above. | C |
<Instruct>: Given the context 'Sequence identity between human pancreatic cholesterol esterase and bile salt-stimulated milk lipase.
', select the correct biomedical concept corresponding to 'bile salt-stimulated milk lipase'. Answer using one of the provided options. | <Options>: A: pancreatic lipase (bos taurus) (aka pancreatic lipase)
B: lipase c, hepatic type (bos taurus) (aka lipase c, hepatic type)
C: carboxyl ester lipase (bos taurus) (aka carboxyl ester lipase)
D: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
E: lipase e, hormone sensitive type (bos taurus) (aka lipase e, hormone sensitive type)
F: None of the above. | D |
<Instruct>: Given the context 'Three overlapping cDNA clones covering the entire primary sequence of the bile salt stimulated lipase in human milk were isolated from a human breast lambda gt10 cDNA library by screening with the rat pancreatic cholesterol esterase cDNA.', select the correct biomedical concept corresponding to 'pancreatic cholesterol esterase'. Answer using one of the provided options. | <Options>: A: carboxyl ester lipase (oryctolagus cuniculus) (aka carboxyl ester lipase)
B: pancreatic lipase (homo sapiens) (aka pancreatic lipase)
C: lipase e, hormone sensitive type (oryctolagus cuniculus) (aka lipase e, hormone sensitive type)
D: lipase e, hormone sensitive type (sus scrofa) (aka lipase e, hormone sensitive type)
E: liver carboxylesterase (sus scrofa) (aka liver carboxylesterase)
F: None of the above. | F |
<Instruct>: Given the context 'Nucleotide sequencing of the cDNA showed that the human milk lipase mRNA encodes a 748-residue protein, including a 23-residue signal peptide.', select the correct biomedical concept corresponding to 'milk lipase'. Answer using one of the provided options. | <Options>: A: lipase, gastric (mus musculus) (aka lipase, gastric)
B: carboxyl ester lipase (bos taurus) (aka carboxyl ester lipase)
C: pancreatic lipase (bos taurus) (aka pancreatic lipase)
D: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
E: lipase h (gallus gallus) (aka lipase h)
F: None of the above. | D |
<Instruct>: Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', select the correct biomedical concept corresponding to 'milk lipase'. Answer using one of the provided options. | <Options>: A: lipase, gastric (mus musculus) (aka lipase, gastric)
B: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
C: pancreatic lipase (bos taurus) (aka pancreatic lipase)
D: monoglyceride lipase (gallus gallus) (aka monoglyceride lipase)
E: carboxyl ester lipase (gallus gallus) (aka carboxyl ester lipase)
F: None of the above. | B |
<Instruct>: Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', select the correct biomedical concept corresponding to 'pancreatic cholesterol esterase'. Answer using one of the provided options. | <Options>: A: pancreatic lipase (homo sapiens) (aka pancreatic lipase)
B: lipase e, hormone sensitive type (sus scrofa) (aka lipase e, hormone sensitive type)
C: lipase e, hormone sensitive type (homo sapiens) (aka lipase e, hormone sensitive type)
D: lipase e, hormone sensitive type (oryctolagus cuniculus) (aka lipase e, hormone sensitive type)
E: liver carboxylesterase (sus scrofa) (aka liver carboxylesterase)
F: None of the above. | F |
<Instruct>: Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', select the correct biomedical concept corresponding to 'milk lipase'. Answer using one of the provided options. | <Options>: A: lipase (mus musculus) (aka lipase, endothelial)
B: monoglyceride lipase (gallus gallus) (aka monoglyceride lipase)
C: lipase h (gallus gallus) (aka lipase h)
D: lipase, gastric (mus musculus) (aka lipase, gastric)
E: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
F: None of the above. | E |
<Instruct>: Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', select the correct biomedical concept corresponding to 'milk lipase'. Answer using one of the provided options. | <Options>: A: carboxyl ester lipase (gallus gallus) (aka carboxyl ester lipase)
B: carboxyl ester lipase (bos taurus) (aka carboxyl ester lipase)
C: lipase (mus musculus) (aka lipase, endothelial)
D: pancreatic triacylglycerol lipase-like (gallus gallus) (aka pancreatic triacylglycerol lipase-like)
E: pancreatic lipase (bos taurus) (aka pancreatic lipase)
F: None of the above. | F |
<Instruct>: Given the context 'The human milk lipase cDNA is highly homologous to rat pancreatic cholesterol esterase, suggesting that the milk lipase may be identical to the cholesterol esterase in human pancreas.', select the correct biomedical concept corresponding to 'cholesterol esterase'. Answer using one of the provided options. | <Options>: A: carboxyl ester lipase (sus scrofa) (aka carboxyl ester lipase)
B: carboxylesterase 1 (oryctolagus cuniculus) (aka carboxylesterase 1)
C: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
D: carboxyl ester lipase (oryctolagus cuniculus) (aka carboxyl ester lipase)
E: lipase e, hormone sensitive type (homo sapiens) (aka lipase e, hormone sensitive type)
F: None of the above. | C |
<Instruct>: Given the context 'This conclusion was confirmed by isolation and sequencing of the cDNA for human pancreatic cholesterol esterase.', select the correct biomedical concept corresponding to 'pancreatic cholesterol esterase'. Answer using one of the provided options. | <Options>: A: pancreatic lipase (homo sapiens) (aka pancreatic lipase)
B: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
C: lipase e, hormone sensitive type (homo sapiens) (aka lipase e, hormone sensitive type)
D: carboxyl ester lipase (oryctolagus cuniculus) (aka carboxyl ester lipase)
E: lipase e, hormone sensitive type (oryctolagus cuniculus) (aka lipase e, hormone sensitive type)
F: None of the above. | B |
<Instruct>: Given the context 'Analysis of the sequence for the human cholesterol esterase/milk lipase revealed similarities to other serine esterases in three distinct regions of the protein.', select the correct biomedical concept corresponding to 'cholesterol esterase'. Answer using one of the provided options. | <Options>: A: lipase e, hormone sensitive type (homo sapiens) (aka lipase e, hormone sensitive type)
B: carboxyl ester lipase (oryctolagus cuniculus) (aka carboxyl ester lipase)
C: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
D: cocaine esterase (oryctolagus cuniculus) (loc127491327 (oryctolagus cuniculus)) (aka cocaine esterase)
E: neutral cholesterol ester hydrolase 1 (homo sapiens) (aka neutral cholesterol ester hydrolase 1)
F: None of the above. | C |
<Instruct>: Given the context 'Analysis of the sequence for the human cholesterol esterase/milk lipase revealed similarities to other serine esterases in three distinct regions of the protein.', select the correct biomedical concept corresponding to 'milk lipase'. Answer using one of the provided options. | <Options>: A: pancreatic triacylglycerol lipase-like (gallus gallus) (aka pancreatic triacylglycerol lipase-like)
B: carboxyl ester lipase (bos taurus) (aka carboxyl ester lipase)
C: carboxyl ester lipase (homo sapiens) (aka carboxyl ester lipase)
D: lipase h (gallus gallus) (aka lipase h)
E: carboxyl ester lipase (gallus gallus) (aka carboxyl ester lipase)
F: None of the above. | C |
<Instruct>: Given the context 'Complete primary structure of the E1 beta subunit of human branched chain alpha-ketoacid dehydrogenase complex deduced from the nucleotide sequence and a gene analysis of patients with this disease.
', select the correct biomedical concept corresponding to 'e1 beta subunit'. Answer using one of the provided options. | <Options>: A: branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens) (aka branched chain keto acid dehydrogenase e1 subunit beta)
B: branched chain ketoacid dehydrogenase e1, beta polypeptide (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
C: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
D: branched chain keto acid dehydrogenase e1 subunit beta (rattus norvegicus) (aka branched chain keto acid dehydrogenase e1 subunit beta)
E: pyruvate dehydrogenase e1 subunit beta (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
F: None of the above. | A |
<Instruct>: Given the context 'A defect in the E1 beta subunit of the branched chain alpha-ketoacid dehydrogenase (BCKDH) complex is one cause of maple syrup urine disease (MSUD).', select the correct biomedical concept corresponding to 'e1 beta subunit'. Answer using one of the provided options. | <Options>: A: bckdh e1-beta (homo sapiens) (aka branched chain keto acid dehydrogenase e1 subunit beta)
B: e1betad (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
C: pyruvate dehydrogenase e1 subunit beta (oryctolagus cuniculus) (aka pyruvate dehydrogenase e1 subunit beta)
D: branched chain ketoacid dehydrogenase e1, beta polypeptide (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
E: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
F: None of the above. | A |
<Instruct>: Given the context 'In an attempt to elucidate the molecular basis of MSUD, we isolated and characterized a 1.35 kbp cDNA clone encoding the entire precursor of the E1 beta subunit of BCKDH complex from a human placental cDNA library.', select the correct biomedical concept corresponding to 'e1 beta subunit'. Answer using one of the provided options. | <Options>: A: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
B: e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)) (aka branched chain keto acid dehydrogenase e1 subunit beta)
C: branched chain ketoacid dehydrogenase e1, beta polypeptide (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
D: branched chain keto acid dehydrogenase e1 subunit beta (rattus norvegicus) (aka branched chain keto acid dehydrogenase e1 subunit beta)
E: pyruvate dehydrogenase e1 subunit beta (oryctolagus cuniculus) (aka pyruvate dehydrogenase e1 subunit beta)
F: None of the above. | B |
<Instruct>: Given the context 'Nucleotide sequence analysis revealed that the isolated cDNA clone (lambda hBE1 beta-1) contained a 5'-untranslated sequence of four nucleotides, the translated sequence of 1,176 nucleotides and the 3'-untranslated sequence of 169 nucleotides.', select the correct biomedical concept corresponding to 'hbe1 beta-1'. Answer using one of the provided options. | <Options>: A: sodium channel epithelial 1 subunit beta (homo sapiens) (aka sodium channel epithelial 1 subunit beta)
B: g protein subunit beta 1 (homo sapiens) (aka g protein subunit beta 1)
C: hbe1 (homo sapiens) (aka hemoglobin subunit epsilon 1)
D: calcium voltage-gated channel auxiliary subunit beta 1 (homo sapiens) (aka calcium voltage-gated channel auxiliary subunit beta 1)
E: hemoglobin subunit beta pseudogene 1 (homo sapiens) (aka hemoglobin subunit beta pseudogene 1)
F: None of the above. | F |
<Instruct>: Given the context 'Comparison of the amino acid sequence predicted from the nucleotide sequence of the cDNA insert of the clone with the NH2-terminal amino acid sequence of the purified mature bovine BCKDH-E1 beta subunit showed that the cDNA insert encodes for a 342-amino acid subunit with a Mr = 37,585.', select the correct biomedical concept corresponding to 'bckdh-e1 beta subunit'. Answer using one of the provided options. | <Options>: A: pdhe1b (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
B: branched chain ketoacid dehydrogenase e1, beta polypeptide (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
C: e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)) (aka branched chain keto acid dehydrogenase e1 subunit beta)
D: None of the above. | D |
<Instruct>: Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', select the correct biomedical concept corresponding to 'e1 beta'. Answer using one of the provided options. | <Options>: A: e1b (mus musculus) (aka small nucleolar rna, h/aca box 73a)
B: branched chain keto acid dehydrogenase e1 subunit beta (rattus norvegicus) (aka branched chain keto acid dehydrogenase e1 subunit beta)
C: e1c (homo sapiens) (aka small nucleolar rna, h/aca box 73b)
D: bckdh e1-beta (homo sapiens) (aka branched chain keto acid dehydrogenase e1 subunit beta)
E: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
F: None of the above. | D |
<Instruct>: Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', select the correct biomedical concept corresponding to 'e1 beta'. Answer using one of the provided options. | <Options>: A: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
B: pdhe1b (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
C: e1b (mus musculus) (aka small nucleolar rna, h/aca box 73a)
D: branched chain keto acid dehydrogenase e1 subunit beta (rattus norvegicus) (aka branched chain keto acid dehydrogenase e1 subunit beta)
E: e1c (homo sapiens) (aka small nucleolar rna, h/aca box 73b)
F: None of the above. | F |
<Instruct>: Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', select the correct biomedical concept corresponding to 'bckdh-e1 beta'. Answer using one of the provided options. | <Options>: A: bckdh e1-beta (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
B: branched chain keto acid dehydrogenase e1 subunit beta (sus scrofa) (aka branched chain keto acid dehydrogenase e1 subunit beta)
C: bckde1b (homo sapiens) (aka branched chain keto acid dehydrogenase e1 subunit beta)
D: pdhe1b (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
E: None of the above. | E |
<Instruct>: Given the context 'A search for protein homology revealed that the primary structure of human BCKDH-E1 beta was similar to the bovine BCKDH-E1 beta and to the E1 beta subunit of human pyruvate dehydrogenase complex, in all regions.', select the correct biomedical concept corresponding to 'e1 beta subunit'. Answer using one of the provided options. | <Options>: A: e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)) (aka branched chain keto acid dehydrogenase e1 subunit beta)
B: pyruvate dehydrogenase e1 subunit beta (oryctolagus cuniculus) (aka pyruvate dehydrogenase e1 subunit beta)
C: branched chain keto acid dehydrogenase e1 subunit beta (rattus norvegicus) (aka branched chain keto acid dehydrogenase e1 subunit beta)
D: pdhe1b (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
E: branched chain ketoacid dehydrogenase e1, beta polypeptide (mus musculus) (aka branched chain ketoacid dehydrogenase e1, beta polypeptide)
F: None of the above. | A |
<Instruct>: Given the context 'Genomic DNA from lymphoblastoid cell lines derived from normal and five MSUD patients, in whom E1 beta was not detected by immunoblot analysis, gave the same restriction maps on Southern blot analysis.', select the correct biomedical concept corresponding to 'e1 beta'. Answer using one of the provided options. | <Options>: A: e1b (homo sapiens) (branched chain keto acid dehydrogenase e1 subunit beta (homo sapiens)) (aka branched chain keto acid dehydrogenase e1 subunit beta)
B: pyruvate dehydrogenase e1 subunit beta (rattus norvegicus) (aka pyruvate dehydrogenase e1 subunit beta)
C: e1c (homo sapiens) (aka small nucleolar rna, h/aca box 73b)
D: pyruvate dehydrogenase e1 subunit beta (homo sapiens) (aka pyruvate dehydrogenase e1 subunit beta)
E: e1b (mus musculus) (aka small nucleolar rna, h/aca box 73a)
F: None of the above. | A |
<Instruct>: Given the context 'Sequence and expression of a human type II mesothelial keratin.
', select the correct biomedical concept corresponding to 'type ii mesothelial keratin'. Answer using one of the provided options. | <Options>: A: krt1-2 (mus musculus) (aka keratin 32)
B: krt-2 (mus musculus) (aka keratin 1 complex)
C: krt-2.1 (mus musculus) (aka keratin 1)
D: krt2-3 (mus musculus) (aka keratin 84)
E: keratin 2 (mus musculus) (aka keratin 2)
F: None of the above. | F |
<Instruct>: Given the context 'A cloned cDNA encoding keratin K7 (55 kD) was identified by positive hybrid selection.', select the correct biomedical concept corresponding to 'k7'. Answer using one of the provided options. | <Options>: A: k77 (mus musculus) (aka keratin 77)
B: krt7 (mus musculus) (aka keratin 7)
C: k9 (mus musculus) (aka keratin 9)
D: k7 (homo sapiens) (keratin 7 (homo sapiens)) (aka keratin 7)
E: k6 (mus musculus) (aka keratin 6)
F: None of the above. | D |
<Instruct>: Given the context 'Southern Blot analysis indicated that this sequence is represented only once in the human genome, and Northern Blot analysis demonstrated that the gene encoding K7 is expressed in abundance in cultured bronchial and mesothelial cells, but only weakly in cultured epidermal cells and not at all in liver, colon, or exocervical tissue.', select the correct biomedical concept corresponding to 'k7'. Answer using one of the provided options. | <Options>: A: k8 (mus musculus) (aka keratin 8)
B: krt7 (homo sapiens) (aka keratin 7)
C: k6 (mus musculus) (aka keratin 6)
D: k7 (mus musculus) (keratin 7 (mus musculus)) (aka keratin 7)
E: k6a (mus musculus) (aka keratin 6a)
F: None of the above. | B |
<Instruct>: Given the context 'The predicted amino acid sequence of this keratin has revealed a striking difference between this keratin and the type II keratins expressed in epidermal cells: whereas all of the epidermal type II keratins thus far sequenced have long nonhelical termini rich in glycine and serine, this mesothelial type II keratin has amino and carboxy terminal regions that are unusually short and lack the inexact repeats of glycine and serine residues.', select the correct biomedical concept corresponding to 'mesothelial type ii keratin'. Answer using one of the provided options. | <Options>: A: krt-2.6 (mus musculus) (aka keratin 6)
B: keratin 2 (mus musculus) (aka keratin 2)
C: krt2-1 (mus musculus) (aka keratin 1)
D: krt1-2 (mus musculus) (aka keratin 32)
E: krt-2 (mus musculus) (aka keratin 1 complex)
F: None of the above. | F |
<Instruct>: Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', select the correct biomedical concept corresponding to 'melanoma-associated antigen p97'. Answer using one of the provided options. | <Options>: A: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
B: cep97 (homo sapiens) (aka centrosomal protein 97)
C: ct97 (homo sapiens) (aka lymphocyte antigen 6 family member k)
D: map97 (homo sapiens) (aka melanotransferrin)
E: hel97 (homo sapiens) (aka mitochondrial rrna methyltransferase 2)
F: None of the above. | D |
<Instruct>: Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', select the correct biomedical concept corresponding to 'melanotransferrin'. Answer using one of the provided options. | <Options>: A: melanotransferrin (homo sapiens) (aka melanotransferrin)
B: melanotransferrin (oryctolagus cuniculus) (aka melanotransferrin)
C: melanotransferrin (gallus gallus) (aka melanotransferrin)
D: melanotransferrinl homeolog (xenopus laevis) (aka melanotransferrinl homeolog)
E: melanotransferrin (bos taurus) (aka melanotransferrin)
F: None of the above. | A |
<Instruct>: Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: p97 (homo sapiens) (valosin containing protein (homo sapiens)) (aka valosin containing protein)
B: p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster)) (aka regulatory particle non-atpase 1)
C: map97 (homo sapiens) (aka melanotransferrin)
D: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
E: p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens)) (aka proteasome 26s subunit ubiquitin receptor, non-atpase 2)
F: None of the above. | C |
<Instruct>: Given the context 'Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence.
p97 is a cell-surface glycoprotein that is present in most human melanomas but only in trace amounts in normal adult tissues.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
B: hspc197 (homo sapiens) (aka bet1 golgi vesicular membrane trafficking protein like)
C: p97 (bos taurus) (aka valosin containing protein)
D: p97 (drosophila melanogaster) (regulatory particle non-atpase 1 (drosophila melanogaster)) (aka regulatory particle non-atpase 1)
E: p97 (homo sapiens) (valosin containing protein (homo sapiens)) (aka valosin containing protein)
F: None of the above. | F |
<Instruct>: Given the context 'To determine the structure of this tumor-associated antigen and to identify its functional domains, we have purified and cloned p97 mRNA and determined its nucleotide sequence.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens)) (aka proteasome 26s subunit ubiquitin receptor, non-atpase 2)
B: p97 (bos taurus) (aka valosin containing protein)
C: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
D: hspc197 (homo sapiens) (aka bet1 golgi vesicular membrane trafficking protein like)
E: map97 (homo sapiens) (aka melanotransferrin)
F: None of the above. | E |
<Instruct>: Given the context 'The mRNA encodes a 738-residue precursor, which contains the previously determined N-terminal amino acid sequence of p97.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: hspc197 (homo sapiens) (aka bet1 golgi vesicular membrane trafficking protein like)
B: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
C: map97 (homo sapiens) (aka melanotransferrin)
D: ec97 (homo sapiens) (aka vps35 endosomal protein sorting factor like)
E: p97 (bos taurus) (aka valosin containing protein)
F: None of the above. | C |
<Instruct>: Given the context 'After removal of a 19-residue signal peptide, the mature p97 molecule comprises extracellular domains of 342 and 352 residues and a C-terminal 25-residue stretch of predominantly uncharged and hydrophobic amino acids, which we believe acts as a membrane anchor.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
B: hspc197 (homo sapiens) (aka bet1 golgi vesicular membrane trafficking protein like)
C: (vcp)/p97 (drosophila melanogaster) (aka transitional endoplasmic reticulum 94)
D: p97 (homo sapiens) (valosin containing protein (homo sapiens)) (aka valosin containing protein)
E: map97 (homo sapiens) (aka melanotransferrin)
F: None of the above. | E |
<Instruct>: Given the context 'Protease digestion studies show that the three major antigenic determinants of p97 are present on the N-terminal domain.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens)) (aka proteasome 26s subunit ubiquitin receptor, non-atpase 2)
B: map97 (homo sapiens) (aka melanotransferrin)
C: (vcp)/p97 (drosophila melanogaster) (aka transitional endoplasmic reticulum 94)
D: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
E: ec97 (homo sapiens) (aka vps35 endosomal protein sorting factor like)
F: None of the above. | B |
<Instruct>: Given the context 'The domains are strikingly homologous to each other (46% amino acid sequence homology) and to the corresponding domains of human serum transferrin (39% homology).', select the correct biomedical concept corresponding to 'transferrin'. Answer using one of the provided options. | <Options>: A: tf (homo sapiens) (transferrin (homo sapiens)) (aka transferrin)
B: tfrc (gallus gallus) (aka transferrin receptor)
C: tf (drosophila melanogaster) (transferrin 1 (drosophila melanogaster)) (aka transferrin 1)
D: transferrin (ovotransferrin) (gallus gallus) (aka transferrin (ovotransferrin))
E: transferrin receptor (homo sapiens) (aka transferrin receptor)
F: None of the above. | A |
<Instruct>: Given the context 'Conservation of disulfide bridges and of amino acids thought to compose the iron binding pockets suggests that p97 is also related to transferrin in tertiary structure and function.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: map97 (homo sapiens) (aka melanotransferrin)
B: hspc197 (homo sapiens) (aka bet1 golgi vesicular membrane trafficking protein like)
C: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
D: p97 (bos taurus) (aka valosin containing protein)
E: p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens)) (aka proteasome 26s subunit ubiquitin receptor, non-atpase 2)
F: None of the above. | A |
<Instruct>: Given the context 'Conservation of disulfide bridges and of amino acids thought to compose the iron binding pockets suggests that p97 is also related to transferrin in tertiary structure and function.', select the correct biomedical concept corresponding to 'transferrin'. Answer using one of the provided options. | <Options>: A: tf (drosophila melanogaster) (transferrin 1 (drosophila melanogaster)) (aka transferrin 1)
B: tf (homo sapiens) (transferrin (homo sapiens)) (aka transferrin)
C: transferrin (ovotransferrin) (gallus gallus) (aka transferrin (ovotransferrin))
D: transferrin receptor (homo sapiens) (aka transferrin receptor)
E: transferrin receptor (gallus gallus) (aka transferrin receptor)
F: None of the above. | B |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'p97'. Answer using one of the provided options. | <Options>: A: map97 (homo sapiens) (aka melanotransferrin)
B: p97 (drosophila melanogaster) (transitional endoplasmic reticulum 94 (drosophila melanogaster)) (aka transitional endoplasmic reticulum 94)
C: hspc97 (homo sapiens) (aka tubulin gamma complex component 2)
D: p97 (homo sapiens) (proteasome 26s subunit ubiquitin receptor, non-atpase 2 (homo sapiens)) (aka proteasome 26s subunit ubiquitin receptor, non-atpase 2)
E: ec97 (homo sapiens) (aka vps35 endosomal protein sorting factor like)
F: None of the above. | A |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'melanotransferrin'. Answer using one of the provided options. | <Options>: A: melanotransferrin (mus musculus) (aka melanotransferrin)
B: melanotransferrin (gallus gallus) (aka melanotransferrin)
C: melanotransferrinl homeolog (xenopus laevis) (aka melanotransferrinl homeolog)
D: melanotransferrin (xenopus tropicalis) (aka melanotransferrin)
E: mtf1 (homo sapiens) (melanotransferrin (homo sapiens)) (aka melanotransferrin)
F: None of the above. | E |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'serotransferrin'. Answer using one of the provided options. | <Options>: A: lactotransferrin (homo sapiens) (aka lactotransferrin)
B: transferrin receptor (homo sapiens) (aka transferrin receptor)
C: transferrin (sus scrofa) (aka transferrin)
D: hemiferrin, transferrin-like protein (rattus norvegicus) (aka hemiferrin, transferrin-like protein)
E: transferrin (homo sapiens) (aka transferrin)
F: None of the above. | E |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'serotransferrin'. Answer using one of the provided options. | <Options>: A: lactotransferrin (homo sapiens) (aka lactotransferrin)
B: otoferlin (homo sapiens) (aka otoferlin)
C: transferrin receptor (homo sapiens) (aka transferrin receptor)
D: serotransferrin (glycine max) (aka serotransferrin)
E: transferrin (ovotransferrin) (gallus gallus) (aka transferrin (ovotransferrin))
F: None of the above. | F |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'lactotransferrin'. Answer using one of the provided options. | <Options>: A: lactotransferrin (sus scrofa) (aka lactotransferrin)
B: lactoferrin (xenopus tropicalis) (aka transferrin)
C: lactotransferrin (homo sapiens) (aka lactotransferrin)
D: lactoferrin (xenopus laevis) (transferrin l homeolog (xenopus laevis)) (aka transferrin l homeolog)
E: ferritin light chain (homo sapiens) (aka ferritin light chain)
F: None of the above. | C |
<Instruct>: Given the context 'We propose that p97 be renamed melanotransferrin to denote its original identification in melanoma cells and its evolutionary relationship to serotransferrin and lactotransferrin, the other members of the transferrin superfamily.', select the correct biomedical concept corresponding to 'transferrin'. Answer using one of the provided options. | <Options>: A: tfrc (gallus gallus) (aka transferrin receptor)
B: transferrin (homo sapiens) (aka transferrin)
C: transferrin (ovotransferrin) (gallus gallus) (aka transferrin (ovotransferrin))
D: tf (drosophila melanogaster) (transferrin 1 (drosophila melanogaster)) (aka transferrin 1)
E: transferrin receptor (homo sapiens) (aka transferrin receptor)
F: None of the above. | B |
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