instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Evidence for genetic duplication giving rise to the BCM1 region on mouse chromosome 1 and the CD2/LFA3 region on mouse chromosome 3.
', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: lfa3 (homo sapiens) (aka cd58 molecule)
C: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
D: cd11a (homo sapiens) (aka integrin subunit alpha l)
E: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
F: None of the above. | B |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: bcm-1 (mus musculus) (aka cd48 antigen)
C: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
D: bcrm1 (homo sapiens) (aka sideroflexin 4)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | B |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'ox45'. Answer using one of the provided options. | <Options>: A: olr45 (rattus norvegicus) (aka olfactory receptor family 52 subfamily k member 2)
B: g protein-coupled receptor 45 (rattus norvegicus) (aka g protein-coupled receptor 45)
C: or4c45 (homo sapiens) (aka olfactory receptor family 4 subfamily c member 45 (gene/pseudogene))
D: gpr45 (homo sapiens) (aka g protein-coupled receptor 45)
E: of45 (rattus norvegicus) (aka matrix extracellular phosphoglycoprotein)
F: None of the above. | F |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'blast-1'. Answer using one of the provided options. | <Options>: A: bcgf-1 (homo sapiens) (aka interleukin 4)
B: blast-1 (mus musculus) (aka cd48 antigen)
C: kit ligand (homo sapiens) (aka kit ligand)
D: blast1 (homo sapiens) (aka cd48 molecule)
E: bm-001 (homo sapiens) (aka cyclin l1)
F: None of the above. | D |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: bcm1 (mus musculus) (aka cd48 antigen)
C: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
D: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: cd11a (homo sapiens) (aka integrin subunit alpha l)
B: lfa-3 (homo sapiens) (aka cd58 molecule)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: lfa-2 (homo sapiens) (aka cd2 molecule)
E: leu-3 (homo sapiens) (aka cd4 molecule)
F: None of the above. | B |
<Instruct>: Given the context 'The mouse BCM1 (OX45, Blast-1) antigen has been cDNA cloned and sequenced to provide data supporting the view that BCM1, LFA3, and CD2 constitute a subgroup within the Ig superfamily.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (bos taurus) (aka cd2 molecule)
B: cd2 molecule (homo sapiens) (aka cd2 molecule)
C: cd228 (homo sapiens) (aka melanotransferrin)
D: cd21 (homo sapiens) (aka complement c3d receptor 2)
E: cd22 (homo sapiens) (aka cd22 molecule)
F: None of the above. | B |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (mus musculus) (aka cd48 antigen)
B: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
C: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
D: bcm1 (homo sapiens) (aka cd48 molecule)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | D |
<Instruct>: Given the context 'Mouse BCM1 is widely expressed on leukocytes and is likely to be anchored to the cell surface by a glycosyl-phosphatidylinositol anchor, as is the case for rat and human BCM1 antigen.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
D: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
E: bcm-1 (mus musculus) (aka cd48 antigen)
F: None of the above. | B |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
D: bcm1 (mus musculus) (aka cd48 antigen)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | D |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcrm1 (homo sapiens) (aka sideroflexin 4)
B: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
C: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
D: bcm1 (homo sapiens) (aka cd48 molecule)
E: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
F: None of the above. | F |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcmp1 (homo sapiens) (aka transmembrane protein 47)
C: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
D: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
E: bcm-1 (mus musculus) (aka cd48 antigen)
F: None of the above. | E |
<Instruct>: Given the context 'Genetic linkage studies by recombination and pulse field analysis showed the BCM1 locus (Bcm-1) to be on distal mouse chromosome 1 and to be linked within 1,600 kb to the locus for an ATPase alpha chain gene (Atpa-3).', select the correct biomedical concept corresponding to 'atpa-3'. Answer using one of the provided options. | <Options>: A: atp13a3 (xenopus tropicalis) (aka atpase type 13a3)
B: atp1a3 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 3)
C: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
D: atppa3 (arabidopsis thaliana) (aka pyrophosphorylase 3)
E: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
F: None of the above. | E |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
C: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
D: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
E: bcm1 (homo sapiens) (aka cd48 molecule)
F: None of the above. | E |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
B: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
C: bcm1 (homo sapiens) (aka cd48 molecule)
D: bcm1 (mus musculus) (aka cd48 antigen)
E: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
F: None of the above. | C |
<Instruct>: Given the context 'A similar relationship was established between the human BCM1 locus (BCM1) and ATP1A2, and other markers on chromosome 1q.', select the correct biomedical concept corresponding to 'atp1a2'. Answer using one of the provided options. | <Options>: A: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
B: atp2a2 (homo sapiens) (aka atpase sarcoplasmic/endoplasmic reticulum ca2+ transporting 2)
C: atp2c1a (homo sapiens) (aka atpase secretory pathway ca2+ transporting 1)
D: atp1al2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 4)
E: atpase na+/k+ transporting subunit alpha 2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
F: None of the above. | E |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 molecule (bos taurus) (aka cd2 molecule)
B: cd2 (homo sapiens) (aka cd2 molecule)
C: cd21 (homo sapiens) (aka complement c3d receptor 2)
D: cd22 (homo sapiens) (aka cd22 molecule)
E: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
F: None of the above. | B |
<Instruct>: Given the context 'A similar situation is seen in the region of the CD2 and LFA3 genes between mouse chromosome 3 and human chromosome 1p.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
C: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
D: lfa-3 (homo sapiens) (aka cd58 molecule)
E: cd11a (homo sapiens) (aka integrin subunit alpha l)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd228 (homo sapiens) (aka melanotransferrin)
B: cd22 molecule (homo sapiens) (aka cd22 molecule)
C: cd2 molecule (homo sapiens) (aka cd2 molecule)
D: cd2 (gallus gallus) (aka cd2 molecule)
E: cd21 (homo sapiens) (aka complement c3d receptor 2)
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
B: lfa-2 (homo sapiens) (aka cd2 molecule)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-1'. Answer using one of the provided options. | <Options>: A: atp synthase f1 subunit alpha pseudogene 1 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 1)
B: atpi (homo sapiens) (aka atp synthase inhibitory factor subunit 1)
C: atpa (escherichia coli str. k-12 substr. mg1655) (aka atp synthase f1 complex subunit alpha)
D: atp6a (homo sapiens) (aka atpase h+/k+ transporting subunit alpha)
E: atpia (homo sapiens) (aka atpase phospholipid transporting 8a1)
F: None of the above. | F |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-1'. Answer using one of the provided options. | <Options>: A: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
B: atp synthase f1 subunit alpha pseudogene 1 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 1)
C: atpa (escherichia coli str. k-12 substr. mg1655) (aka atp synthase f1 complex subunit alpha)
D: atpi (homo sapiens) (aka atp synthase inhibitory factor subunit 1)
E: atpia (homo sapiens) (aka atpase phospholipid transporting 8a1)
F: None of the above. | F |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atp1a1'. Answer using one of the provided options. | <Options>: A: atpase na+/k+ transporting subunit alpha 1 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 1)
B: atp1al1 (homo sapiens) (aka atpase h+/k+ transporting non-gastric alpha2 subunit)
C: atp6n1a (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
D: atp1a3 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 3)
E: atp5a1 (homo sapiens) (aka atp synthase f1 subunit alpha)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: mb-1 (homo sapiens) (aka cd79a molecule)
C: mbt-1 (homo sapiens) (aka l3mbtl histone methyl-lysine binding protein 3)
D: bcm-1 (mus musculus) (aka cd48 antigen)
E: bcmp1 (homo sapiens) (aka transmembrane protein 47)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
E: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atpa-3'. Answer using one of the provided options. | <Options>: A: atp synthase f1 subunit alpha pseudogene 3 (homo sapiens) (aka atp synthase f1 subunit alpha pseudogene 3)
B: atpaf1 (homo sapiens) (aka atp synthase mitochondrial f1 complex assembly factor 1)
C: atp13a3 (homo sapiens) (aka atpase 13a3)
D: atpa-3 (mus musculus) (aka atpase, na+/k+ transporting, alpha 2 polypeptide)
E: atp13a3 (xenopus tropicalis) (aka atpase type 13a3)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, the CD2/LFA3 genes are linked within 580 kb to Atpa-1/ATP1A1 genes to provide a parallel situation to the linkage between Bcm-1/BCM1 and Atpa-3/ATP1A2 on chromosomes 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'atp1a2'. Answer using one of the provided options. | <Options>: A: atp1a2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 2)
B: atp1a2 (rattus norvegicus) (aka atpase na+/k+ transporting subunit alpha 2)
C: atp6a2 (homo sapiens) (aka atpase h+ transporting v0 subunit a2)
D: atp1al2 (homo sapiens) (aka atpase na+/k+ transporting subunit alpha 4)
E: atp2c1a (homo sapiens) (aka atpase secretory pathway ca2+ transporting 1)
F: None of the above. | A |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcm1 (homo sapiens) (aka cd48 molecule)
B: bcrm1 (homo sapiens) (aka sideroflexin 4)
C: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
D: bcm-1 (mus musculus) (aka cd48 antigen)
E: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
F: None of the above. | A |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
B: cd2 molecule (homo sapiens) (aka cd2 molecule)
C: cd2 molecule (bos taurus) (aka cd2 molecule)
D: cd228 (homo sapiens) (aka melanotransferrin)
E: cd2 (gallus gallus) (aka cd2 molecule)
F: None of the above. | B |
<Instruct>: Given the context 'Taken together, the data suggest duplication of a chromosome region including the precursors of the genes for BCM1, CD2, and LFA3, and the ATPase genes to give rise to the linkage groups now observed.', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa3 (homo sapiens) (aka cd58 molecule)
B: lfa1a (homo sapiens) (aka integrin subunit alpha l)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: lfa-2 (homo sapiens) (aka cd2 molecule)
E: leu-3 (homo sapiens) (aka cd4 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 molecule (bos taurus) (aka cd2 molecule)
B: cd2 (homo sapiens) (aka cd2 molecule)
C: cd228 (homo sapiens) (aka melanotransferrin)
D: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
E: cd21 (homo sapiens) (aka complement c3d receptor 2)
F: None of the above. | B |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa3 (homo sapiens) (aka cd58 molecule)
B: leu-3 (homo sapiens) (aka cd4 molecule)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: cd11a (homo sapiens) (aka integrin subunit alpha l)
E: lfa-2 (homo sapiens) (aka cd2 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: leu-3 (homo sapiens) (aka cd4 molecule)
B: itga3 (homo sapiens) (aka integrin subunit alpha 3)
C: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
D: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
E: lfa-2 (homo sapiens) (aka cd2 molecule)
F: None of the above. | F |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
D: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
E: bcrm1 (homo sapiens) (aka sideroflexin 4)
F: None of the above. | B |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: lfa3 (homo sapiens) (aka cd58 molecule)
B: lfa1a (homo sapiens) (aka integrin subunit alpha l)
C: lfa-1 (homo sapiens) (integrin subunit beta 2 (homo sapiens)) (aka integrin subunit beta 2)
D: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
E: lfa-2 (homo sapiens) (aka cd2 molecule)
F: None of the above. | A |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'cd2'. Answer using one of the provided options. | <Options>: A: cd2 (gallus gallus) (aka cd2 molecule)
B: cd2 locus control region (homo sapiens) (aka cd2 locus control region)
C: cd228 (homo sapiens) (aka melanotransferrin)
D: cd2 molecule (homo sapiens) (aka cd2 molecule)
E: cd21 (homo sapiens) (aka complement c3d receptor 2)
F: None of the above. | D |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'lfa3'. Answer using one of the provided options. | <Options>: A: slamf3 (homo sapiens) (aka lymphocyte antigen 9)
B: lfa-2 (homo sapiens) (aka cd2 molecule)
C: leu-3 (homo sapiens) (aka cd4 molecule)
D: lfa3 (homo sapiens) (aka cd58 molecule)
E: integrin subunit alpha 3 (homo sapiens) (aka integrin subunit alpha 3)
F: None of the above. | D |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: cdcbm1 (homo sapiens) (aka tubulin beta 3 class iii)
B: bcm (homo sapiens) (aka tnf receptor superfamily member 17)
C: cnnm1 (bos taurus) (aka cyclin and cbs domain divalent metal cation transport mediator 1)
D: bcm1 (homo sapiens) (aka cd48 molecule)
E: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
F: None of the above. | D |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm-1'. Answer using one of the provided options. | <Options>: A: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
B: bcm-1 (mus musculus) (aka cd48 antigen)
C: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
D: bcsc-1 (homo sapiens) (aka von willebrand factor a domain containing 5a)
E: bcmp1 (homo sapiens) (aka transmembrane protein 47)
F: None of the above. | B |
<Instruct>: Given the context 'The duplicated regions may have stayed together on chromosome 1 in the human (with the insertion of a centromere), while in the mouse, the genetic regions are proposed to have become dispersed in the formation of chromosomes 1 and 3. CD2 and LFA3 are more dissimilar in sequence than BCM1 and LFA3, and if the precursors of the CD2 and LFA3 loci formed before the proposed chromosome segment duplication, then a gene encoding a recognizer molecule for BCM1 may exist in linkage with Bcm-1/BCM1 on chromosome 1 (mouse) and 1q (human).', select the correct biomedical concept corresponding to 'bcm1'. Answer using one of the provided options. | <Options>: A: bcms1 (homo sapiens) (aka deleted in lymphocytic leukemia 1)
B: bcm1 (homo sapiens) (aka cd48 molecule)
C: mbc1 (homo sapiens) (aka coiled-coil domain containing 112)
D: bcmo1 (homo sapiens) (aka beta-carotene oxygenase 1)
E: bcrm1 (homo sapiens) (aka sideroflexin 4)
F: None of the above. | B |
<Instruct>: Given the context 'The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.
', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfr-rp (homo sapiens) (aka lymphotoxin beta receptor)
B: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
C: tnfr1 (homo sapiens) (aka tnf receptor superfamily member 1a)
D: None of the above. | C |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tumor necrosis factor'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (oryctolagus cuniculus) (aka tumor necrosis factor)
B: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
C: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
D: tnf (homo sapiens) (aka tumor necrosis factor)
E: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | D |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: tnfb (homo sapiens) (aka lymphotoxin alpha)
D: tnfc (homo sapiens) (aka lymphotoxin beta)
E: tnf (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'Two proteins which specifically bind tumor necrosis factor (TNF) have recently been isolated from human urine in our laboratory.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnfb (homo sapiens) (aka lymphotoxin alpha)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: None of the above. | E |
<Instruct>: Given the context 'Antibodies against one of the two TNF binding proteins (TBPI) were found to have effects characteristic of TNF, including stimulating phosphorylation of specific cellular proteins.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
B: tnfb (homo sapiens) (aka lymphotoxin alpha)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: tnf (homo sapiens) (aka tumor necrosis factor)
E: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | D |
<Instruct>: Given the context 'Oligonucleotide probes designed on the basis of the NH2-terminal amino acid sequence of TBPI were used to clone the cDNA for the structurally related cell surface type 1 TNF-R. It is notable that although this receptor can signal the phosphorylation of cellular proteins, it appears from its amino acid sequence to be devoid of intrinsic protein kinase activity.', select the correct biomedical concept corresponding to 'cell surface type 1 tnf-r'. Answer using one of the provided options. | <Options>: A: tnfbr (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tnf receptor superfamily member 1a (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
D: dcr1-tnfr (homo sapiens) (aka tnf receptor superfamily member 10c)
E: None of the above. | B |
<Instruct>: Given the context 'The extracellular domain of the receptor is composed of four internal cysteine-rich repeats, homologous to structures repeated four times in the extracellular domains of the nerve growth factor receptor and the B lymphocytes surface antigen CDw40.', select the correct biomedical concept corresponding to 'nerve growth factor receptor'. Answer using one of the provided options. | <Options>: A: ngfr (xenopus tropicalis) (nerve growth factor receptor (xenopus tropicalis)) (aka nerve growth factor receptor)
B: p75tnfr (homo sapiens) (aka tnf receptor superfamily member 1b)
C: nerve growth factor receptor (rattus norvegicus) (aka nerve growth factor receptor)
D: ngfr (homo sapiens) (aka nerve growth factor receptor)
E: nerve growth factor receptor (bos taurus) (aka nerve growth factor receptor)
F: None of the above. | D |
<Instruct>: Given the context 'The extracellular domain of the receptor is composed of four internal cysteine-rich repeats, homologous to structures repeated four times in the extracellular domains of the nerve growth factor receptor and the B lymphocytes surface antigen CDw40.', select the correct biomedical concept corresponding to 'cdw40'. Answer using one of the provided options. | <Options>: A: ox40 (homo sapiens) (aka tnf receptor superfamily member 4)
B: interleukin 4 receptor (homo sapiens) (aka interleukin 4 receptor)
C: cd40l (homo sapiens) (aka cd40 ligand)
D: cd40 molecule (homo sapiens) (aka cd40 molecule)
E: il-40 (homo sapiens) (aka chromosome 17 open reading frame 99)
F: None of the above. | D |
<Instruct>: Given the context 'The amino acid composition and size of the extracellular domain of the type I TNF-R closely resemble those of TBPI.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tnfar (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
D: None of the above. | B |
<Instruct>: Given the context 'The COOH-terminal amino acid sequence of the four cysteine rich repeats within the extracellular domain of the type I TNF-R matches the COOH-terminal sequence of TBPI.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
B: tnfr1 (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfbr (homo sapiens) (aka tnf receptor superfamily member 1b)
D: None of the above. | B |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type ii tnf-r'. Answer using one of the provided options. | <Options>: A: tnf-r-ii (homo sapiens) (aka tnf receptor superfamily member 1b)
B: tnfr3 (homo sapiens) (aka lymphotoxin beta receptor)
C: tnf-r (homo sapiens) (aka tnf receptor superfamily member 1a)
D: trailr2 (homo sapiens) (aka tnf receptor superfamily member 10b)
E: None of the above. | A |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'tbpii'. Answer using one of the provided options. | <Options>: A: tata-box binding protein like 2 (bos taurus) (aka tata-box binding protein like 2)
B: tata-box binding protein like 2 (xenopus tropicalis) (aka tata-box binding protein like 2)
C: tbp-b (xenopus tropicalis) (aka tata-box binding protein)
D: tbp2 (xenopus laevis) (aka tata-box binding protein like 2 l homeolog)
E: tbpii (homo sapiens) (aka tnf receptor superfamily member 1b)
F: None of the above. | E |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
B: tnf-r-ii (homo sapiens) (aka tnf receptor superfamily member 1b)
C: tnfr1 (homo sapiens) (aka tnf receptor superfamily member 1a)
D: None of the above. | C |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
B: tnf-r-i (homo sapiens) (aka tnf receptor superfamily member 1a)
C: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
D: None of the above. | B |
<Instruct>: Given the context 'On the other hand, amino acid sequences in the soluble form of the type II TNF-R (TBPII), while indicating a marked homology of structure, did not suggest any identity between this protein and the extracellular domain of the type I TNF-R. CHO cells transfected with type I TNF-R cDNA produced both cell surface and soluble forms of the receptor.', select the correct biomedical concept corresponding to 'type i tnf-r'. Answer using one of the provided options. | <Options>: A: tnfcr (homo sapiens) (aka lymphotoxin beta receptor)
B: tnfr2 (homo sapiens) (aka tnf receptor superfamily member 1b)
C: None of the above. | C |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
B: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
E: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
F: None of the above. | E |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: hyaluronan mediated motility receptor (homo sapiens) (aka hyaluronan mediated motility receptor)
B: cd44 (sus scrofa) (aka cd44 molecule)
C: cd44 molecule (in blood group) (homo sapiens) (aka cd44 molecule (in blood group))
D: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
E: cd44 molecule (in blood group) (oryctolagus cuniculus) (aka cd44 molecule (in blood group))
F: None of the above. | C |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
B: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
D: tex6 (homo sapiens) (aka rna polymerase i subunit h)
E: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
F: None of the above. | B |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tumor necrosis factor'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (oryctolagus cuniculus) (aka tumor necrosis factor)
B: tnf (homo sapiens) (aka tumor necrosis factor)
C: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
D: tumor necrosis factor (xenopus tropicalis) (aka tumor necrosis factor)
E: tnfb (homo sapiens) (aka lymphotoxin alpha)
F: None of the above. | B |
<Instruct>: Given the context 'A novel secretory tumor necrosis factor-inducible protein (TSG-6) is a member of the family of hyaluronate binding proteins, closely related to the adhesion receptor CD44.
TSG-6 cDNA was isolated by differential screening of a lambda cDNA library prepared from tumor necrosis factor (TNF)-treated human diploid FS-4 fibroblasts.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfc (homo sapiens) (aka lymphotoxin beta)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
D: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | C |
<Instruct>: Given the context 'We show that TSG-6 mRNA was not detectable in untreated cells, but became readily induced by TNF in normal human fibroblast lines and in peripheral blood mononuclear cells.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
B: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
C: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
D: tnf alpha induced protein 6 (homo sapiens) (aka tnf alpha induced protein 6)
E: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
F: None of the above. | D |
<Instruct>: Given the context 'We show that TSG-6 mRNA was not detectable in untreated cells, but became readily induced by TNF in normal human fibroblast lines and in peripheral blood mononuclear cells.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfb (homo sapiens) (aka lymphotoxin alpha)
B: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
C: tnfc (homo sapiens) (aka lymphotoxin beta)
D: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
E: tnfa (homo sapiens) (aka tumor necrosis factor)
F: None of the above. | E |
<Instruct>: Given the context 'In contrast, TSG-6 mRNA was undetectable in either control or TNF-treated human vascular endothelial cells and a variety of tumor-derived or virus-transformed cell lines.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
B: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
C: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
D: tex6 (homo sapiens) (aka rna polymerase i subunit h)
E: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
F: None of the above. | C |
<Instruct>: Given the context 'In contrast, TSG-6 mRNA was undetectable in either control or TNF-treated human vascular endothelial cells and a variety of tumor-derived or virus-transformed cell lines.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
B: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
C: tnfa (homo sapiens) (aka tumor necrosis factor)
D: tnfc (homo sapiens) (aka lymphotoxin beta)
E: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
F: None of the above. | C |
<Instruct>: Given the context 'The sequence of full-length TSG-6 cDNA revealed one major open reading frame predicting a polypeptide of 277 amino acids, including a typical cleavable signal peptide.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
B: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
D: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | B |
<Instruct>: Given the context 'The sequence of full-length TSG-6 cDNA revealed one major open reading frame predicting a polypeptide of 277 amino acids, including a typical cleavable signal peptide.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
B: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
C: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
D: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
E: tex6 (homo sapiens) (aka rna polymerase i subunit h)
F: None of the above. | F |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
B: testis expressed transcript, y-linked 6 (homo sapiens) (aka testis expressed transcript, y-linked 6)
C: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
D: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | A |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'cartilage link protein'. Answer using one of the provided options. | <Options>: A: protein linkin (caenorhabditis elegans) (aka protein linkin)
B: cap-gly domain-containing linker protein 1 homolog (caenorhabditis elegans) (aka cap-gly domain-containing linker protein 1 homolog)
C: hyaluronan and proteoglycan link protein 3 (homo sapiens) (aka hyaluronan and proteoglycan link protein 3)
D: hyaluronan and proteoglycan link protein 1 (mus musculus) (aka hyaluronan and proteoglycan link protein 1)
E: hyaluronan and proteoglycan link protein 1 (homo sapiens) (aka hyaluronan and proteoglycan link protein 1)
F: None of the above. | E |
<Instruct>: Given the context 'The NH2-terminal half of the predicted TSG-6 protein sequence shows a significant homology with a region implicated in hyaluronate binding, present in cartilage link protein, proteoglycan core proteins, and the adhesion receptor CD44.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: cd44 (mus musculus) (aka cd44 antigen)
B: cd44 (sus scrofa) (aka cd44 molecule)
C: cd44 molecule (in blood group) (homo sapiens) (aka cd44 molecule (in blood group))
D: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
E: hyaluronan mediated motility receptor (homo sapiens) (aka hyaluronan mediated motility receptor)
F: None of the above. | C |
<Instruct>: Given the context 'The most extensive sequence homology exists between the predicted TSG-6 protein and CD44.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tnf alpha induced protein 6 (homo sapiens) (aka tnf alpha induced protein 6)
B: tex6 (homo sapiens) (aka rna polymerase i subunit h)
C: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
D: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
E: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
F: None of the above. | A |
<Instruct>: Given the context 'The most extensive sequence homology exists between the predicted TSG-6 protein and CD44.', select the correct biomedical concept corresponding to 'cd44'. Answer using one of the provided options. | <Options>: A: cd44 molecule (sus scrofa) (aka cd44 molecule)
B: cd44 molecule (in blood group) (oryctolagus cuniculus) (aka cd44 molecule (in blood group))
C: cd44 molecule (in blood group) (homo sapiens) (aka cd44 molecule (in blood group))
D: cd44 molecule (in blood group) (xenopus tropicalis) (aka cd44 molecule (in blood group))
E: cd44 antigen (mus musculus) (aka cd44 antigen)
F: None of the above. | C |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
B: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
C: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
D: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
E: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
F: None of the above. | D |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor (homo sapiens) (aka tumor necrosis factor)
B: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
C: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
D: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
E: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
F: None of the above. | A |
<Instruct>: Given the context 'Western blot analysis with an antiserum raised against a TSG-6 fusion protein detected a 39-kD glycoprotein in the supernatants of TNF-treated FS-4 cells and of cells transfected with TSG-6 cDNA.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
B: tsg6 (homo sapiens) (aka tnf alpha induced protein 6)
C: tex6 (homo sapiens) (aka rna polymerase i subunit h)
D: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
E: tsg7 (homo sapiens) (aka suppression of tumorigenicity 7)
F: None of the above. | B |
<Instruct>: Given the context 'Binding of the TSG-6 protein to hyaluronate was demonstrated by coprecipitation.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
B: melanoma-associated transcript 6 (homo sapiens) (aka melanoma-associated transcript 6)
C: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
D: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
E: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
F: None of the above. | C |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
B: tnfb (homo sapiens) (aka lymphotoxin alpha)
C: tnf (homo sapiens) (aka tumor necrosis factor)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: tnfc (homo sapiens) (aka lymphotoxin beta)
F: None of the above. | C |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tnf'. Answer using one of the provided options. | <Options>: A: tnfsf1 (homo sapiens) (aka lymphotoxin alpha)
B: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
C: tnf superfamily member 4 (homo sapiens) (aka tnf superfamily member 4)
D: tnf superfamily member 10 (homo sapiens) (aka tnf superfamily member 10)
E: None of the above. | E |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'il-1'. Answer using one of the provided options. | <Options>: A: il1f1 (homo sapiens) (aka interleukin 1 alpha)
B: ilf-1 (homo sapiens) (aka forkhead box k2)
C: il-1 (homo sapiens) (aka interleukin 1 beta)
D: il-1h (homo sapiens) (aka interleukin 37)
E: il-1h1 (homo sapiens) (aka interleukin 36 gamma)
F: None of the above. | C |
<Instruct>: Given the context 'Our data indicate that the inflammatory cytokine (TNF or IL-1)-inducible, secretory TSG-6 protein is a novel member of the family of hyaluronate binding proteins, possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.', select the correct biomedical concept corresponding to 'tsg-6'. Answer using one of the provided options. | <Options>: A: tsg-6 (homo sapiens) (aka tnf alpha induced protein 6)
B: tsg-6 (mus musculus) (aka tumor necrosis factor alpha induced protein 6)
C: tex6 (homo sapiens) (aka rna polymerase i subunit h)
D: tsg-6 (bos taurus) (aka tnf alpha induced protein 6)
E: tsg-9 (homo sapiens) (aka tumor suppressor candidate 1)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis.
', select the correct biomedical concept corresponding to 'cdc2'. Answer using one of the provided options. | <Options>: A: cdc2 (saccharomyces cerevisiae s288c) (aka dna-directed dna polymerase delta pol3)
B: cdc21 (saccharomyces cerevisiae s288c) (aka thymidylate synthase)
C: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
D: cdc27 (homo sapiens) (aka cell division cycle 27)
E: anaphase promoting complex subunit cdc23 (saccharomyces cerevisiae s288c) (aka anaphase promoting complex subunit cdc23)
F: None of the above. | C |
<Instruct>: Given the context 'We now present cloning of a cDNA coding for CHED (cholinesterase-related cell division controller), a human homolog of the Schizosaccharomyces pombe cell division cycle 2 (cdc2)-like kinases, universal controllers of the mitotic cell cycle.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched1 (homo sapiens) (aka ovo like zinc finger 2)
B: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
C: ched (escherichia coli str. k-12 substr. mg1655) (aka methyl-accepting chemotaxis protein tsr)
D: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
E: chedda (homo sapiens) (aka atrophin 1)
F: None of the above. | D |
<Instruct>: Given the context 'We now present cloning of a cDNA coding for CHED (cholinesterase-related cell division controller), a human homolog of the Schizosaccharomyces pombe cell division cycle 2 (cdc2)-like kinases, universal controllers of the mitotic cell cycle.', select the correct biomedical concept corresponding to 'cholinesterase-related cell division controller'. Answer using one of the provided options. | <Options>: A: cell division cycle 42, like (danio rerio) (aka cell division cycle 42, like)
B: connector enhancer of kinase suppressor of ras 2-like (gallus gallus) (aka connector enhancer of kinase suppressor of ras 2-like)
C: hdc homolog, cell cycle regulator (xenopus tropicalis) (aka hdc homolog, cell cycle regulator)
D: crndep (homo sapiens) (aka colorectal neoplasia differentially expressed)
E: crescerin-like protein che-12 (caenorhabditis elegans) (aka crescerin-like protein che-12)
F: None of the above. | F |
<Instruct>: Given the context 'Library screening, RNA blot hybridization, and direct PCR amplification of cDNA reverse-transcribed from cellular mRNA revealed that CHED mRNA is expressed in multiple tissues, including bone marrow.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: chrd (gallus gallus) (aka chordin)
B: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
C: ched1 (homo sapiens) (aka ovo like zinc finger 2)
D: chegdd (homo sapiens) (aka oxidation resistance 1)
E: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
F: None of the above. | E |
<Instruct>: Given the context 'The CHED protein includes the consensus ATP binding and phosphorylation domains characteristic of kinases, displays 34-42% identically aligned amino acid residues with other cdc2-related kinases, and is considerably longer at its amino and carboxyl termini.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched (escherichia coli str. k-12 substr. mg1655) (aka methyl-accepting chemotaxis protein tsr)
B: chrd (gallus gallus) (aka chordin)
C: ched-related (drosophila melanogaster) (aka uncharacterized protein)
D: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
E: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
F: None of the above. | D |
<Instruct>: Given the context 'An antisense oligodeoxynucleotide designed to interrupt CHED's expression (AS-CHED) significantly reduced the ratio between CHED mRNA and actin mRNA within 1 hr of its addition to cultures, a reduction that persisted for 4 days.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched (xenopus laevis) (aka cyclin-dependent kinase 13 l homeolog)
B: chrd (gallus gallus) (aka chordin)
C: ched1 (homo sapiens) (aka ovo like zinc finger 2)
D: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
E: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
F: None of the above. | D |
<Instruct>: Given the context 'An antisense oligodeoxynucleotide designed to interrupt CHED's expression (AS-CHED) significantly reduced the ratio between CHED mRNA and actin mRNA within 1 hr of its addition to cultures, a reduction that persisted for 4 days.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched1 (homo sapiens) (aka ovo like zinc finger 2)
B: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
C: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
D: chrd (gallus gallus) (aka chordin)
E: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
F: None of the above. | B |
<Instruct>: Given the context 'An antisense oligodeoxynucleotide designed to interrupt CHED's expression (AS-CHED) significantly reduced the ratio between CHED mRNA and actin mRNA within 1 hr of its addition to cultures, a reduction that persisted for 4 days.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched (xenopus laevis) (aka cyclin-dependent kinase 13 l homeolog)
B: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
C: chrd (gallus gallus) (aka chordin)
D: ched1 (homo sapiens) (aka ovo like zinc finger 2)
E: ched-related (drosophila melanogaster) (aka uncharacterized protein)
F: None of the above. | B |
<Instruct>: Given the context 'An antisense oligodeoxynucleotide designed to interrupt CHED's expression (AS-CHED) significantly reduced the ratio between CHED mRNA and actin mRNA within 1 hr of its addition to cultures, a reduction that persisted for 4 days.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched-related (drosophila melanogaster) (aka uncharacterized protein)
B: ched (escherichia coli str. k-12 substr. mg1655) (aka methyl-accepting chemotaxis protein tsr)
C: ched1 (homo sapiens) (aka ovo like zinc finger 2)
D: chedda (homo sapiens) (aka atrophin 1)
E: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
F: None of the above. | F |
<Instruct>: Given the context 'AS-CHED treatment selectively inhibited megakaryocyte development in murine bone marrow cultures but did not prevent other hematopoietic pathways, as evidenced by increasing numbers of mononuclear cells.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: chrd (gallus gallus) (aka chordin)
B: ched-related (drosophila melanogaster) (aka uncharacterized protein)
C: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
D: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
E: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
F: None of the above. | D |
<Instruct>: Given the context 'An oligodeoxynucleotide blocking production of the acetylcholine-hydrolyzing enzyme, butyrylcholinesterase, displayed a similar inhibition of megakaryocytopoiesis.', select the correct biomedical concept corresponding to 'butyrylcholinesterase'. Answer using one of the provided options. | <Options>: A: butyrylcholinesterase (homo sapiens) (aka butyrylcholinesterase)
B: butyrylcholinesterase (sus scrofa) (aka butyrylcholinesterase)
C: butyrylcholinesterase (mus musculus) (aka butyrylcholinesterase)
D: butyrylcholinesterase (gallus gallus) (aka butyrylcholinesterase)
E: butyrylcholinesterase (oryctolagus cuniculus) (aka butyrylcholinesterase)
F: None of the above. | A |
<Instruct>: Given the context 'In contrast, an oligodeoxynucleotide blocking production of the human 2Hs cdc2 homolog interfered with production of the human 2Hs cdc2 homolog interfered with cellular proliferation without altering the cell-type composition of these cultures.', select the correct biomedical concept corresponding to 'cdc2'. Answer using one of the provided options. | <Options>: A: cdc21 (saccharomyces cerevisiae s288c) (aka thymidylate synthase)
B: cdc2 (homo sapiens) (dna polymerase delta 1, catalytic subunit (homo sapiens)) (aka dna polymerase delta 1, catalytic subunit)
C: anaphase promoting complex subunit cdc27 (saccharomyces cerevisiae s288c) (aka anaphase promoting complex subunit cdc27)
D: cdc28 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase cdc28)
E: p34cdc2 (homo sapiens) (aka cyclin dependent kinase 1)
F: None of the above. | E |
<Instruct>: Given the context 'In contrast, an oligodeoxynucleotide blocking production of the human 2Hs cdc2 homolog interfered with production of the human 2Hs cdc2 homolog interfered with cellular proliferation without altering the cell-type composition of these cultures.', select the correct biomedical concept corresponding to 'cdc2'. Answer using one of the provided options. | <Options>: A: cdc28 (saccharomyces cerevisiae s288c) (aka cyclin-dependent serine/threonine-protein kinase cdc28)
B: cdc27 (homo sapiens) (aka cell division cycle 27)
C: anaphase promoting complex subunit cdc23 (saccharomyces cerevisiae s288c) (aka anaphase promoting complex subunit cdc23)
D: cdc2 (homo sapiens) (cyclin dependent kinase 1 (homo sapiens)) (aka cyclin dependent kinase 1)
E: cdc2 (saccharomyces cerevisiae s288c) (aka dna-directed dna polymerase delta pol3)
F: None of the above. | D |
<Instruct>: Given the context 'Therefore, these findings strengthen the link between cholinergic signaling and cell division control in hematopoiesis and implicate both CHED and cholinesterases in this differentiation process.', select the correct biomedical concept corresponding to 'ched'. Answer using one of the provided options. | <Options>: A: ched-related (drosophila melanogaster) (aka uncharacterized protein)
B: ched (homo sapiens) (cyclin dependent kinase 13 (homo sapiens)) (aka cyclin dependent kinase 13)
C: cesd (homo sapiens) (aka lipase a, lysosomal acid type)
D: ched1 (homo sapiens) (aka ovo like zinc finger 2)
E: choline dehydrogenase (homo sapiens) (aka choline dehydrogenase)
F: None of the above. | B |
<Instruct>: Given the context 'The transmembrane desmosomal glycoproteins have been proposed to play a role in cell adhesion; desmoglein I (DGI) is a major member of this class of desmosomal molecules.', select the correct biomedical concept corresponding to 'desmoglein i'. Answer using one of the provided options. | <Options>: A: desmoglein 4 (homo sapiens) (aka desmoglein 4)
B: dsg1 (homo sapiens) (aka desmoglein 1)
C: desmoglein 1 (sus scrofa) (aka desmoglein 1)
D: desmoglein 1 (xenopus tropicalis) (aka desmoglein 1)
E: desmoglein 1 (bos taurus) (aka desmoglein 1)
F: None of the above. | B |
<Instruct>: Given the context 'The transmembrane desmosomal glycoproteins have been proposed to play a role in cell adhesion; desmoglein I (DGI) is a major member of this class of desmosomal molecules.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgsi (mus musculus) (aka ess-2 splicing factor)
B: dgki (homo sapiens) (aka diacylglycerol kinase iota)
C: dgic (homo sapiens) (aka placenta associated 8)
D: dg1 (homo sapiens) (aka desmoglein 1)
E: dgi (mus musculus) (aka desmoglein 1 alpha)
F: None of the above. | D |
<Instruct>: Given the context 'However, evidence supporting a role for DGI in cell adhesion or in the plaque is lacking.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgdi (drosophila melanogaster) (aka gdp dissociation inhibitor)
B: dgki (homo sapiens) (aka diacylglycerol kinase iota)
C: dg1 (homo sapiens) (aka desmoglein 1)
D: dgic (homo sapiens) (aka placenta associated 8)
E: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
F: None of the above. | C |
<Instruct>: Given the context 'In order to begin to understand DGI function we have identified human cDNA clones encoding the entire mature polypeptide of 1000 amino acids.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgsi (mus musculus) (aka ess-2 splicing factor)
B: dg1 (homo sapiens) (aka desmoglein 1)
C: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
D: dgdi (drosophila melanogaster) (aka gdp dissociation inhibitor)
E: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
F: None of the above. | B |
<Instruct>: Given the context 'Our data suggest that like the bovine DGI molecule human DGI is highly related to the calcium-dependent class of cell adhesion molecules known as cadherins.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgic (homo sapiens) (aka placenta associated 8)
B: dgdi (drosophila melanogaster) (aka gdp dissociation inhibitor)
C: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
D: dg1 (homo sapiens) (aka desmoglein 1)
E: dgi (mus musculus) (aka desmoglein 1 alpha)
F: None of the above. | F |
<Instruct>: Given the context 'Our data suggest that like the bovine DGI molecule human DGI is highly related to the calcium-dependent class of cell adhesion molecules known as cadherins.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgi1 (homo sapiens) (aka dentin sialophosphoprotein)
B: dgic (homo sapiens) (aka placenta associated 8)
C: dgmii (drosophila melanogaster) (aka alpha-mannosidase class ii a)
D: dgi (mus musculus) (aka desmoglein 1 alpha)
E: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
F: None of the above. | F |
<Instruct>: Given the context 'Our data suggest that like the bovine DGI molecule human DGI is highly related to the calcium-dependent class of cell adhesion molecules known as cadherins.', select the correct biomedical concept corresponding to 'dgi'. Answer using one of the provided options. | <Options>: A: dgi (mus musculus) (aka desmoglein 1 alpha)
B: dg1 (homo sapiens) (aka desmoglein 1)
C: dgdi (drosophila melanogaster) (aka gdp dissociation inhibitor)
D: dgmii (drosophila melanogaster) (aka alpha-mannosidase class ii a)
E: dgsi (homo sapiens) (aka ess-2 spliceosome associated protein)
F: None of the above. | B |
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