instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Isolation and sequence of a cDNA clone for human calcineurin B, the Ca2+-binding subunit of the Ca2+/calmodulin-stimulated protein phosphatase.
', select the correct biomedical concept corresponding to 'calcineurin b'. Answer using one of the provided options. | <Options>: A: cnb (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, alpha)
B: pp2cbeta (homo sapiens) (aka protein phosphatase, mg2+/mn2+ dependent 1b)
C: cnb (drosophila melanogaster) (calcineurin b (drosophila melanogaster)) (aka calcineurin b)
D: scnn1b-b (xenopus tropicalis) (aka sodium channel, non voltage gated 1 beta subunit)
E: protein phosphatase 3 regulatory subunit b, beta (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, beta)
F: None of the above. | A |
<Instruct>: Given the context 'We have identified and cloned human cDNA for the Ca2+-binding subunit of calcineurin, the brain isozyme of the Ca2+/calmodulin-stimulated protein phosphatase.', select the correct biomedical concept corresponding to 'ca2+-binding subunit of calcineurin'. Answer using one of the provided options. | <Options>: A: calna1 (homo sapiens) (aka protein phosphatase 3 catalytic subunit alpha)
B: caln1 (homo sapiens) (aka calneuron 1)
C: cngb1 (xenopus tropicalis) (aka cyclic nucleotide gated channel beta 1)
D: pp2cbeta (homo sapiens) (aka protein phosphatase, mg2+/mn2+ dependent 1b)
E: calnb1 (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, alpha)
F: None of the above. | E |
<Instruct>: Given the context 'The deduced sequence of the human protein differs from bovine brain calcineurin B by an additional valine at the carboxyl terminus and substitution of Met-11 and Ser-153 by cysteine.', select the correct biomedical concept corresponding to 'calcineurin b'. Answer using one of the provided options. | <Options>: A: protein phosphatase 3 regulatory subunit b, beta (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, beta)
B: scnn1b-b (xenopus tropicalis) (aka sodium channel, non voltage gated 1 beta subunit)
C: prkcbb (xenopus tropicalis) (aka protein kinase c beta)
D: cnb (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, alpha)
E: calnb (homo sapiens) (aka protein phosphatase 3 catalytic subunit beta)
F: None of the above. | D |
<Instruct>: Given the context 'As was observed with protein levels, mRNA abundance in brain is 20-60 times that found in other tissues with the exception of HeLa cells which, like brain, contain abundant calcineurin B mRNA.', select the correct biomedical concept corresponding to 'calcineurin b'. Answer using one of the provided options. | <Options>: A: can (drosophila melanogaster) (calcineurin b (drosophila melanogaster)) (aka calcineurin b)
B: protein phosphatase 3 catalytic subunit beta (homo sapiens) (aka protein phosphatase 3 catalytic subunit beta)
C: cnb (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, alpha)
D: protein phosphatase 3 regulatory subunit b, beta (homo sapiens) (aka protein phosphatase 3 regulatory subunit b, beta)
E: scnn1b-b (xenopus tropicalis) (aka sodium channel, non voltage gated 1 beta subunit)
F: None of the above. | C |
<Instruct>: Given the context 'Human liver serine dehydratase.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: serine dehydratase like (bos taurus) (aka serine dehydratase like)
B: sds (homo sapiens) (serine dehydratase (homo sapiens)) (aka serine dehydratase)
C: serine dehydratase s homeolog (xenopus laevis) (aka serine dehydratase s homeolog)
D: serine dehydratase (oryctolagus cuniculus) (aka serine dehydratase)
E: serine dehydratase like (homo sapiens) (aka serine dehydratase like)
F: None of the above. | B |
<Instruct>: Given the context 'Rat liver serine dehydratase cDNA was used to screen a human liver cDNA library in lambda gt11.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: serine dehydratase s homeolog (xenopus laevis) (aka serine dehydratase s homeolog)
B: sds (homo sapiens) (serine dehydratase (homo sapiens)) (aka serine dehydratase)
C: serine dehydratase like (homo sapiens) (aka serine dehydratase like)
D: serine dehydratase like (bos taurus) (aka serine dehydratase like)
E: serine dehydratase (sus scrofa) (aka serine dehydratase)
F: None of the above. | F |
<Instruct>: Given the context 'The deduced amino acid sequence, with a calculated Mr of 34,615, was similar to that of rat liver serine dehydratase except for the absence of a segment consisting of 36 amino acid residues.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: serine dehydratase (xenopus tropicalis) (aka serine dehydratase)
B: serine dehydratase s homeolog (xenopus laevis) (aka serine dehydratase s homeolog)
C: serine dehydratase (sus scrofa) (aka serine dehydratase)
D: serine dehydratase (oryctolagus cuniculus) (aka serine dehydratase)
E: serine dehydratase (bos taurus) (aka serine dehydratase)
F: None of the above. | F |
<Instruct>: Given the context 'In vitro transcription/translation with the cDNA resulted in the formation of a polypeptide with an Mr of approximately 35,000, which cross-reacted with the anti-rat serine dehydratase antibody.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: serine dehydratase (bos taurus) (aka serine dehydratase)
B: serine dehydratase like (homo sapiens) (aka serine dehydratase like)
C: serine dehydratase (homo sapiens) (aka serine dehydratase)
D: serine dehydratase (sus scrofa) (aka serine dehydratase)
E: serine dehydratase (xenopus tropicalis) (aka serine dehydratase)
F: None of the above. | F |
<Instruct>: Given the context 'In vitro transcription/translation with the cDNA resulted in the formation of a polypeptide with an Mr of approximately 35,000, which cross-reacted with the anti-rat serine dehydratase antibody.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: serine dehydratase like (xenopus tropicalis) (aka serine dehydratase like)
B: serine dehydratase (xenopus tropicalis) (aka serine dehydratase)
C: sds (homo sapiens) (serine dehydratase (homo sapiens)) (aka serine dehydratase)
D: serine dehydratase (sus scrofa) (aka serine dehydratase)
E: serine dehydratase (oryctolagus cuniculus) (aka serine dehydratase)
F: None of the above. | F |
<Instruct>: Given the context 'These results suggest that the human serine dehydratase is structurally cognate with the rat enzyme.', select the correct biomedical concept corresponding to 'serine dehydratase'. Answer using one of the provided options. | <Options>: A: sds (homo sapiens) (serine dehydratase (homo sapiens)) (aka serine dehydratase)
B: serine dehydratase (oryctolagus cuniculus) (aka serine dehydratase)
C: serine dehydratase (xenopus tropicalis) (aka serine dehydratase)
D: serine dehydratase s homeolog (xenopus laevis) (aka serine dehydratase s homeolog)
E: serine dehydratase (bos taurus) (aka serine dehydratase)
F: None of the above. | A |
<Instruct>: Given the context 'rac1 and rac2 cDNA clones were isolated from a differentiated HL-60 library and encode proteins that are 92% homologous and share 58% and 26-30% amino acid homology with human rhos and ras, respectively.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: p21-rac1 (homo sapiens) (aka rac family small gtpase 1)
B: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
C: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
D: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
E: rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster)) (aka rac1)
F: None of the above. | A |
<Instruct>: Given the context 'rac1 and rac2 cDNA clones were isolated from a differentiated HL-60 library and encode proteins that are 92% homologous and share 58% and 26-30% amino acid homology with human rhos and ras, respectively.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rac (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
B: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
C: rac (homo sapiens) (aka akt serine/threonine kinase 1)
D: rac family small gtpase 2 (homo sapiens) (aka rac family small gtpase 2)
E: akt2 (homo sapiens) (aka akt serine/threonine kinase 2)
F: None of the above. | D |
<Instruct>: Given the context 'Nucleotide sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with molecular masses of 21,450 and 21,429 daltons, respectively.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
B: rac (drosophila melanogaster) (rac1 (drosophila melanogaster)) (aka rac1)
C: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
D: rac family small gtpase 1 (homo sapiens) (aka rac family small gtpase 1)
E: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
F: None of the above. | D |
<Instruct>: Given the context 'Nucleotide sequence analysis predicts both rac1 and rac2 proteins to contain 192 amino acids with molecular masses of 21,450 and 21,429 daltons, respectively.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rac (homo sapiens) (aka akt serine/threonine kinase 1)
B: rac-beta (homo sapiens) (aka akt serine/threonine kinase 2)
C: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
D: rac2 (homo sapiens) (aka rac family small gtpase 2)
E: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
F: None of the above. | D |
<Instruct>: Given the context 'rac1 and rac2 possess four of the five conserved functional domains in ras associated with binding and hydrolysis of guanine nucleotides.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: p21-rac1 (homo sapiens) (aka rac family small gtpase 1)
B: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
C: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
D: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
E: rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster)) (aka rac1)
F: None of the above. | A |
<Instruct>: Given the context 'rac1 and rac2 possess four of the five conserved functional domains in ras associated with binding and hydrolysis of guanine nucleotides.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
B: rac (homo sapiens) (aka akt serine/threonine kinase 1)
C: rac-beta (homo sapiens) (aka akt serine/threonine kinase 2)
D: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
E: rac2 (homo sapiens) (aka rac family small gtpase 2)
F: None of the above. | E |
<Instruct>: Given the context 'The rac transcripts, particularly rac2, display relative myeloid tissue selectivity.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: akt2 (homo sapiens) (aka akt serine/threonine kinase 2)
B: rac (homo sapiens) (aka akt serine/threonine kinase 1)
C: rac family small gtpase 2 (homo sapiens) (aka rac family small gtpase 2)
D: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
E: rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
F: None of the above. | C |
<Instruct>: Given the context 'Both rac1 transcripts (2.4 and 1.1 kilobases (kb] increase when HL-60 cells differentiate to neutrophil-like morphology.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: p21-rac1 (homo sapiens) (aka rac family small gtpase 1)
B: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
C: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
D: rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster)) (aka rac1)
E: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
F: None of the above. | A |
<Instruct>: Given the context 'rac2 mRNA (1.45 kb) increases 7-9-fold and 3-fold upon differentiation of HL-60 and U937 cells, respectively.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
B: rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
C: rac family small gtpase 2 (homo sapiens) (aka rac family small gtpase 2)
D: rac (homo sapiens) (aka akt serine/threonine kinase 1)
E: rac-beta (homo sapiens) (aka akt serine/threonine kinase 2)
F: None of the above. | C |
<Instruct>: Given the context 'rac2 mRNA (1.45 kb) increases 7-9-fold and 3-fold upon differentiation of HL-60 and U937 cells, respectively.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rac (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
B: rac-beta (homo sapiens) (aka akt serine/threonine kinase 2)
C: rac (homo sapiens) (aka akt serine/threonine kinase 1)
D: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
E: None of the above. | E |
<Instruct>: Given the context 'Neither rac mRNAs are present in a Jurkat T cell line, and unlike rac1, rac2 mRNA is absent in human brain and liver tissue.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: rac family small gtpase 1 (homo sapiens) (aka rac family small gtpase 1)
B: rac1 (drosophila melanogaster) (gtpase rac1 (drosophila melanogaster)) (aka rac1)
C: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
D: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
E: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
F: None of the above. | A |
<Instruct>: Given the context 'Neither rac mRNAs are present in a Jurkat T cell line, and unlike rac1, rac2 mRNA is absent in human brain and liver tissue.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: rac-beta (homo sapiens) (aka akt serine/threonine kinase 2)
B: rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
C: rac (homo sapiens) (aka akt serine/threonine kinase 1)
D: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
E: rac2 (homo sapiens) (aka rac family small gtpase 2)
F: None of the above. | E |
<Instruct>: Given the context 'Transfection experiments permitted the demonstration that rac1 and rac2 are substrates for ADP-ribosylation by the C3 component of botulinum toxin.', select the correct biomedical concept corresponding to 'rac1'. Answer using one of the provided options. | <Options>: A: rac1 (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
B: rac-1 (homo sapiens) (aka rac family small gtpase 1)
C: rac gtpase (drosophila melanogaster) (rac1 (drosophila melanogaster)) (aka rac1)
D: rac1p1 (homo sapiens) (aka rac family small gtpase 1 pseudogene 1)
E: rac1l (rattus norvegicus) (aka rac family small gtpase 1 like)
F: None of the above. | B |
<Instruct>: Given the context 'Transfection experiments permitted the demonstration that rac1 and rac2 are substrates for ADP-ribosylation by the C3 component of botulinum toxin.', select the correct biomedical concept corresponding to 'rac2'. Answer using one of the provided options. | <Options>: A: akt2 (homo sapiens) (aka akt serine/threonine kinase 2)
B: rach2 (homo sapiens) (aka solute carrier family 14 member 1 (kidd blood group))
C: rac family small gtpase 2 (homo sapiens) (aka rac family small gtpase 2)
D: rac (homo sapiens) (aka akt serine/threonine kinase 1)
E: rac gtpase (drosophila melanogaster) (rac2 (drosophila melanogaster)) (aka rac2)
F: None of the above. | C |
<Instruct>: Given the context 'Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases.
', select the correct biomedical concept corresponding to 'cathepsin e'. Answer using one of the provided options. | <Options>: A: cathepsin e (mus musculus) (aka cathepsin e)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: ctse (homo sapiens) (aka cathepsin e)
D: carboxypeptidase e (gallus gallus) (aka carboxypeptidase e)
E: carboxypeptidase e (mus musculus) (aka carboxypeptidase e)
F: None of the above. | C |
<Instruct>: Given the context 'The predicted sequence of human gastric cathepsin E (CTSE) was determined by analysis of cDNA clones isolated from a library constructed with poly(A+) RNA from a gastric adenocarcinoma cell line.', select the correct biomedical concept corresponding to 'cathepsin e'. Answer using one of the provided options. | <Options>: A: peptidase e (homo sapiens) (aka peptidase e)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: ctse (homo sapiens) (aka cathepsin e)
D: cathepsin e (gallus gallus) (aka cathepsin e)
E: cathepsin e (rattus norvegicus) (aka cathepsin e)
F: None of the above. | C |
<Instruct>: Given the context 'The predicted sequence of human gastric cathepsin E (CTSE) was determined by analysis of cDNA clones isolated from a library constructed with poly(A+) RNA from a gastric adenocarcinoma cell line.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
B: ctse (homo sapiens) (aka cathepsin e)
C: ctse (rattus norvegicus) (aka cathepsin e)
D: ctse (gallus gallus) (aka cathepsin e)
E: ctsl (homo sapiens) (aka cathepsin l)
F: None of the above. | B |
<Instruct>: Given the context 'The CTSE cDNA clones were identified using a set of complementary 18-base oligonucleotide probes specific for a 6-residue sequence surrounding the first active site of all previously characterized human aspartic proteinases.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctsa (homo sapiens) (aka cathepsin a)
B: ctsl (homo sapiens) (aka cathepsin l)
C: cathepsin e (homo sapiens) (aka cathepsin e)
D: ctse (gallus gallus) (aka cathepsin e)
E: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Sequence analysis of CTSE cDNA clones revealed a 1188-base pair open reading frame that exhibited 59% sequence identity with human pepsinogen A.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctsl (homo sapiens) (aka cathepsin l)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
D: ctse (gallus gallus) (aka cathepsin e)
E: ctse (homo sapiens) (aka cathepsin e)
F: None of the above. | E |
<Instruct>: Given the context 'The predicted CTSE amino acid sequence includes a 379-residue proenzyme (Mr = 40,883) and a 17-residue signal peptide.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctsh (homo sapiens) (aka cathepsin h)
B: ctse (rattus norvegicus) (aka cathepsin e)
C: ctsl (homo sapiens) (aka cathepsin l)
D: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
E: cathepsin e (homo sapiens) (aka cathepsin e)
F: None of the above. | E |
<Instruct>: Given the context 'The predicted CTSE amino acid sequence includes a 379-residue proenzyme (Mr = 40,883) and a 17-residue signal peptide.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (rattus norvegicus) (aka cathepsin e)
B: ctsl (homo sapiens) (aka cathepsin l)
C: ctse (gallus gallus) (aka cathepsin e)
D: ctsh (homo sapiens) (aka cathepsin h)
E: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'The predicted CTSE amino acid composition was consistent with that of purified material from gastric mucosa and gastric adenocarcinoma cell lines.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
B: ctse (mus musculus) (aka cathepsin e)
C: ctse (gallus gallus) (aka cathepsin e)
D: cathepsin e (homo sapiens) (aka cathepsin e)
E: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
F: None of the above. | D |
<Instruct>: Given the context 'Additional evidence for the identification of the CTSE cDNA clones was obtained by analysis of poly(A+) RNA isolated from CTSE-producing and -nonproducing gastric adenocarcinoma cell subclones.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (mus musculus) (aka cathepsin e)
B: cathepsin e (homo sapiens) (aka cathepsin e)
C: ctse (gallus gallus) (aka cathepsin e)
D: ctse (xenopus laevis) (cathepsin e s homeolog (xenopus laevis)) (aka cathepsin e s homeolog)
E: ctsh (homo sapiens) (aka cathepsin h)
F: None of the above. | B |
<Instruct>: Given the context 'Additional evidence for the identification of the CTSE cDNA clones was obtained by analysis of poly(A+) RNA isolated from CTSE-producing and -nonproducing gastric adenocarcinoma cell subclones.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (homo sapiens) (aka cathepsin e)
B: ctsl (homo sapiens) (aka cathepsin l)
C: ctse (rattus norvegicus) (aka cathepsin e)
D: ctse (gallus gallus) (aka cathepsin e)
E: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
F: None of the above. | A |
<Instruct>: Given the context 'Three RNA transcripts (3.6, 2.6, and 2.1 kilobases) were identified in poly(A+) RNA isolated from a gastric adenocarcinoma cell line that produced CTSE that were absent from nonproducing subclones.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (gallus gallus) (aka cathepsin e)
B: ctse (homo sapiens) (aka cathepsin e)
C: ctsl (homo sapiens) (aka cathepsin l)
D: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
E: ctsh (homo sapiens) (aka cathepsin h)
F: None of the above. | B |
<Instruct>: Given the context 'CTSE contains 7 cysteine residues, of which 6 were localized by comparative maximal alignment analysis with pepsinogen A to conserved residues that form intrachain disulfide bonds.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
B: ctse (gallus gallus) (aka cathepsin e)
C: cathepsin e (homo sapiens) (aka cathepsin e)
D: ctsl (homo sapiens) (aka cathepsin l)
E: ctse (mus musculus) (aka cathepsin e)
F: None of the above. | C |
<Instruct>: Given the context 'The seventh cysteine residue of CTSE is located within the activation peptide region of the proenzyme.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
B: ctse (gallus gallus) (aka cathepsin e)
C: ctsa (homo sapiens) (aka cathepsin a)
D: ctse (homo sapiens) (aka cathepsin e)
E: ctsl (homo sapiens) (aka cathepsin l)
F: None of the above. | D |
<Instruct>: Given the context 'We suspect that this residue forms an interchain disulfide bond and thereby determines the dimerization of CTSE proenzyme molecules that is observed under native conditions.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctsa (homo sapiens) (aka cathepsin a)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: ctse (mus musculus) (aka cathepsin e)
D: ctse (homo sapiens) (aka cathepsin e)
E: ctsl (homo sapiens) (aka cathepsin l)
F: None of the above. | D |
<Instruct>: Given the context 'The CTSE gene was localized to human chromosome 1 by concurrent cytogenetic and cDNA probe analyses of a panel of human x mouse somatic cell hybrids.', select the correct biomedical concept corresponding to 'ctse'. Answer using one of the provided options. | <Options>: A: ctse (mus musculus) (aka cathepsin e)
B: ctsl (homo sapiens) (aka cathepsin l)
C: ctsa (homo sapiens) (aka cathepsin a)
D: ctse (rattus norvegicus) (aka cathepsin e)
E: cathepsin e (homo sapiens) (aka cathepsin e)
F: None of the above. | E |
<Instruct>: Given the context 'Homology between a region of the human retinoblastoma gene and L1 family repetitive sequences.
', select the correct biomedical concept corresponding to 'retinoblastoma'. Answer using one of the provided options. | <Options>: A: rbb (homo sapiens) (aka nacc family member 2)
B: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
C: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
D: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
E: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
F: None of the above. | D |
<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept corresponding to 'retinoblastoma'. Answer using one of the provided options. | <Options>: A: rb-1 (homo sapiens) (aka rna binding motif protein 45)
B: rb1 (homo sapiens) (aka rb transcriptional corepressor 1)
C: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
D: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
E: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
F: None of the above. | B |
<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept corresponding to 'retinoblastoma'. Answer using one of the provided options. | <Options>: A: rb-1 (homo sapiens) (aka rna binding motif protein 45)
B: rb (drosophila melanogaster) (retinoblastoma-family protein 2 (drosophila melanogaster)) (aka retinoblastoma-family protein 2)
C: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
D: rbb (homo sapiens) (aka nacc family member 2)
E: rb3 (homo sapiens) (aka stathmin 4)
F: None of the above. | F |
<Instruct>: Given the context 'Five clones that hybridized weakly with the human retinoblastoma (Rb) gene were obtained by screening a human genomic library in a non-stringent condition.', select the correct biomedical concept corresponding to 'rb'. Answer using one of the provided options. | <Options>: A: rb3 (homo sapiens) (aka stathmin 4)
B: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
C: rbb (homo sapiens) (aka nacc family member 2)
D: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
E: rb1 (homo sapiens) (aka rb transcriptional corepressor 1)
F: None of the above. | E |
<Instruct>: Given the context 'The DNAs of two of these clones were partially sequenced and found to contain a region with considerable homology to part of the Rb gene.', select the correct biomedical concept corresponding to 'rb'. Answer using one of the provided options. | <Options>: A: rb2 (homo sapiens) (aka rb transcriptional corepressor like 2)
B: rb-1 (homo sapiens) (aka rna binding motif protein 45)
C: rb3 (homo sapiens) (aka stathmin 4)
D: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
E: p105-rb (homo sapiens) (aka rb transcriptional corepressor 1)
F: None of the above. | E |
<Instruct>: Given the context 'As the L1 family is transposable, the Rb gene may be inactivated by recombination at this homologous region.', select the correct biomedical concept corresponding to 'rb'. Answer using one of the provided options. | <Options>: A: rb-1 (homo sapiens) (aka rna binding motif protein 45)
B: rb3 (homo sapiens) (aka stathmin 4)
C: rb1 (homo sapiens) (aka rb transcriptional corepressor 1)
D: rbb (homo sapiens) (aka nacc family member 2)
E: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
F: None of the above. | C |
<Instruct>: Given the context 'Another possibility related with the DNA binding properties of Rb and L1 family proteins is also discussed.', select the correct biomedical concept corresponding to 'rb'. Answer using one of the provided options. | <Options>: A: rb-1 (homo sapiens) (aka rna binding motif protein 45)
B: rbl1 (homo sapiens) (aka rb transcriptional corepressor like 1)
C: rbb (homo sapiens) (aka nacc family member 2)
D: prb (homo sapiens) (aka rb transcriptional corepressor 1)
E: rb (drosophila melanogaster) (retinoblastoma-family protein (drosophila melanogaster)) (aka retinoblastoma-family protein)
F: None of the above. | D |
<Instruct>: Given the context 'COUP transcription factor is a member of the steroid receptor superfamily.
', select the correct biomedical concept corresponding to 'coup transcription factor'. Answer using one of the provided options. | <Options>: A: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 s homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 s homeolog)
B: couptf1 (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
D: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
E: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
F: None of the above. | B |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept corresponding to 'coup (chicken ovalbumin upstream promoter) transcription factor'. Answer using one of the provided options. | <Options>: A: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
B: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
C: coup-tfi (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
D: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 s homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 s homeolog)
E: coup1 (xenopus laevis) (nuclear receptor subfamily 2 group f member 2 s homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2 group f member 2 s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'The COUP (chicken ovalbumin upstream promoter) transcription factor (COUP-TF) exists in a number of different tissues and is essential for expression of the chicken ovalbumin gene.', select the correct biomedical concept corresponding to 'coup-tf'. Answer using one of the provided options. | <Options>: A: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
B: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
C: coup-tfi (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
D: coup-tfa (xenopus tropicalis) (aka nuclear receptor subfamily 2, group f, member 5)
E: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
F: None of the above. | C |
<Instruct>: Given the context 'COUP-TF also binds specifically to the rat insulin promoter element, although the two binding sites share little sequence similarity.', select the correct biomedical concept corresponding to 'coup-tf'. Answer using one of the provided options. | <Options>: A: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
B: coup-tf (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
C: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
D: couptf1 (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
E: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
F: None of the above. | D |
<Instruct>: Given the context 'Here we report the isolation of a human complementary DNA clone encoding COUP-TF.', select the correct biomedical concept corresponding to 'coup-tf'. Answer using one of the provided options. | <Options>: A: coup-tfi (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
B: coup-tfa (xenopus tropicalis) (aka nuclear receptor subfamily 2, group f, member 5)
C: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
D: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
E: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
F: None of the above. | A |
<Instruct>: Given the context 'Comparison of the amino-acid sequence of COUP-TF with known sequences reveals that it is a member of the steroid/thyroid hormone/vitamin receptor superfamily.', select the correct biomedical concept corresponding to 'coup-tf'. Answer using one of the provided options. | <Options>: A: couptf1 (homo sapiens) (aka nuclear receptor subfamily 2 group f member 1)
B: coup-tfii (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 2)
C: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
D: coup-tfi (rattus norvegicus) (aka nuclear receptor subfamily 2, group f, member 1)
E: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
F: None of the above. | A |
<Instruct>: Given the context 'Comparison of the amino-acid sequence of COUP-TF with known sequences reveals that it is a member of the steroid/thyroid hormone/vitamin receptor superfamily.', select the correct biomedical concept corresponding to 'coup-tf'. Answer using one of the provided options. | <Options>: A: coup-tfi (xenopus tropicalis) (aka nuclear receptor subfamily 2 group f member 1)
B: couptfb (homo sapiens) (aka nuclear receptor subfamily 2 group f member 2)
C: coup (xenopus laevis) (nuclear receptor subfamily 2, group f, member 5 l homeolog (xenopus laevis)) (aka nuclear receptor subfamily 2, group f, member 5 l homeolog)
D: coup-tfi (bos taurus) (aka nuclear receptor subfamily 2 group f member 1)
E: coup-tfa (xenopus tropicalis) (aka nuclear receptor subfamily 2, group f, member 5)
F: None of the above. | F |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'interleukin-2 receptor beta'. Answer using one of the provided options. | <Options>: A: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
B: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: interleukin 20 receptor subunit beta (homo sapiens) (aka interleukin 20 receptor subunit beta)
E: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
F: None of the above. | C |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'interleukin-2'. Answer using one of the provided options. | <Options>: A: interleukin 2 (homo sapiens) (aka interleukin 2)
B: il22 (homo sapiens) (aka interleukin 22)
C: ilf2 (homo sapiens) (aka interleukin enhancer binding factor 2)
D: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
E: colony stimulating factor 2 (homo sapiens) (aka colony stimulating factor 2)
F: None of the above. | A |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: interleukin 3 (homo sapiens) (aka interleukin 3)
B: interleukin enhancer binding factor 2 (homo sapiens) (aka interleukin enhancer binding factor 2)
C: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
D: interleukin 2 (homo sapiens) (aka interleukin 2)
E: il22 (homo sapiens) (aka interleukin 22)
F: None of the above. | D |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'il-2 receptor alpha'. Answer using one of the provided options. | <Options>: A: il22ra2 (homo sapiens) (aka interleukin 22 receptor subunit alpha 2)
B: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: interleukin 2 receptor subunit alpha (homo sapiens) (aka interleukin 2 receptor subunit alpha)
D: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
E: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
F: None of the above. | C |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'il-2r alpha'. Answer using one of the provided options. | <Options>: A: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
B: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
C: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
D: il2ra (homo sapiens) (aka interleukin 2 receptor subunit alpha)
E: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
F: None of the above. | D |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'p55'. Answer using one of the provided options. | <Options>: A: pp565 (homo sapiens) (aka pp565)
B: d55 (homo sapiens) (aka tpd52 like 3)
C: hp55 (homo sapiens) (aka dna polymerase gamma 2, accessory subunit)
D: p55-r (homo sapiens) (aka tnf receptor superfamily member 1a)
E: p55t (homo sapiens) (aka protein associated with lin7 2, maguk p55 family member)
F: None of the above. | F |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'il-2 receptor beta'. Answer using one of the provided options. | <Options>: A: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
B: interleukin 20 receptor subunit beta (homo sapiens) (aka interleukin 20 receptor subunit beta)
C: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
D: il22r (homo sapiens) (aka interleukin 22 receptor subunit alpha 1)
E: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
F: None of the above. | A |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'il-2r beta'. Answer using one of the provided options. | <Options>: A: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
B: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
D: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
E: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
F: None of the above. | A |
<Instruct>: Given the context 'Interleukin-2 receptor beta chain gene: generation of three receptor forms by cloned human alpha and beta chain cDNA's.
Interleukin-2 (IL-2) binds to two distinct receptor molecules, the IL-2 receptor alpha (IL-2R alpha, p55) chain and the newly identified IL-2 receptor beta (IL-2R beta, p70-75) chain.', select the correct biomedical concept corresponding to 'p70-75'. Answer using one of the provided options. | <Options>: A: pp8875 (homo sapiens) (aka rab, member ras oncogene family like 6)
B: ck-75 (homo sapiens) (aka keratin 75)
C: pp8675 (homo sapiens) (aka pml nuclear body scaffold)
D: rpl7ap75 (homo sapiens) (aka ribosomal protein l7a pseudogene 75)
E: p70-75 (homo sapiens) (aka interleukin 2 receptor subunit beta)
F: None of the above. | E |
<Instruct>: Given the context 'The cDNA encoding the human IL-2R beta chain has now been isolated.', select the correct biomedical concept corresponding to 'il-2r beta'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
B: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
D: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
E: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
F: None of the above. | B |
<Instruct>: Given the context 'The cDNA encoding the human IL-2R beta chain has now been isolated.', select the correct biomedical concept corresponding to 'il-2r beta'. Answer using one of the provided options. | <Options>: A: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
B: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
C: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
D: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
E: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
F: None of the above. | F |
<Instruct>: Given the context 'The overall primary structure of the IL-2R beta chain shows no apparent homology to other known receptors.', select the correct biomedical concept corresponding to 'il-2r beta'. Answer using one of the provided options. | <Options>: A: interleukin 12 receptor subunit beta 2 (homo sapiens) (aka interleukin 12 receptor subunit beta 2)
B: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
E: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
F: None of the above. | C |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept corresponding to 'il-2r alpha'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: il2r (homo sapiens) (aka interleukin 2 receptor subunit alpha)
D: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
E: cd132 (homo sapiens) (aka interleukin 2 receptor subunit gamma)
F: None of the above. | C |
<Instruct>: Given the context 'Unlike the IL-2R alpha chain, the IL-2R beta chain has a large cytoplasmic region in which a functional domain (or domains) mediating an intracellular signal transduction pathway (or pathways) may be embodied.', select the correct biomedical concept corresponding to 'il-2r beta'. Answer using one of the provided options. | <Options>: A: il12rb (homo sapiens) (aka interleukin 12 receptor subunit beta 1)
B: csf2rb2 (homo sapiens) (aka csf2rb pseudogene 1)
C: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: csf2rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
E: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
F: None of the above. | C |
<Instruct>: Given the context 'The cDNA-encoded beta chain binds and internalizes IL-2 when expressed on T lymphoid cells but not fibroblast cells.', select the correct biomedical concept corresponding to 'il-2'. Answer using one of the provided options. | <Options>: A: interleukin 2 (homo sapiens) (aka interleukin 2)
B: interleukin 3 (homo sapiens) (aka interleukin 3)
C: interleukin enhancer binding factor 2 (homo sapiens) (aka interleukin enhancer binding factor 2)
D: il22 (homo sapiens) (aka interleukin 22)
E: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept corresponding to 'il-2 receptor'. Answer using one of the provided options. | <Options>: A: il2rb (homo sapiens) (aka interleukin 2 receptor subunit beta)
B: interleukin 2 receptor subunit gamma (homo sapiens) (aka interleukin 2 receptor subunit gamma)
C: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
D: interleukin 2 receptor subunit alpha (homo sapiens) (aka interleukin 2 receptor subunit alpha)
E: ifn-r-2 (homo sapiens) (aka interferon alpha and beta receptor subunit 2)
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, the cDNA gives rise to the generation of high-affinity IL-2 receptor when co-expressed with the IL-2R alpha chain cDNA.', select the correct biomedical concept corresponding to 'il-2r alpha'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 receptor subunit alpha (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: interleukin 1 receptor type 2 (homo sapiens) (aka interleukin 1 receptor type 2)
D: il-2rg (homo sapiens) (aka interleukin 2 receptor subunit gamma)
E: il2ra (homo sapiens) (aka interleukin 2 receptor subunit alpha)
F: None of the above. | E |
<Instruct>: Given the context 'Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor.
', select the correct biomedical concept corresponding to 'ldl receptor'. Answer using one of the provided options. | <Options>: A: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
B: low density lipoprotein receptor (sus scrofa) (aka low density lipoprotein receptor)
C: low density lipoprotein receptor (homo sapiens) (aka low density lipoprotein receptor)
D: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
E: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
F: None of the above. | C |
<Instruct>: Given the context 'The pathogenesis of Heymann nephritis, a rat model of human membranous glomerulonephritis, depends on the interaction of autoantibodies with a renal glycoprotein (GP330) on glomerular podocytes.', select the correct biomedical concept corresponding to 'gp330'. Answer using one of the provided options. | <Options>: A: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s homeolog (xenopus laevis)) (aka provisional ortholog of zona pellucida glycoprotein 3 s homeolog)
B: gp330 (xenopus laevis) (aka ldl receptor related protein 2 l homeolog)
C: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
D: gp330 (homo sapiens) (aka ldl receptor related protein 2)
E: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Partial complementary DNAs coding for GP330 were isolated and sequenced.', select the correct biomedical concept corresponding to 'gp330'. Answer using one of the provided options. | <Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
B: gp330 (homo sapiens) (aka ldl receptor related protein 2)
C: gp280 (homo sapiens) (aka cubilin)
D: gp330 (xenopus laevis) (aka ldl receptor related protein 2 l homeolog)
E: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
F: None of the above. | B |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept corresponding to 'low density lipoprotein (ldl) receptor'. Answer using one of the provided options. | <Options>: A: low density lipoprotein receptor (sus scrofa) (aka low density lipoprotein receptor)
B: ldlr (homo sapiens) (aka low density lipoprotein receptor)
C: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
D: apolipoprotein b receptor (homo sapiens) (aka apolipoprotein b receptor)
E: lrp1 (homo sapiens) (ldl receptor related protein 1 (homo sapiens)) (aka ldl receptor related protein 1)
F: None of the above. | B |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept corresponding to 'low density lipoprotein (ldl) receptor'. Answer using one of the provided options. | <Options>: A: low density lipoprotein receptor (rattus norvegicus) (aka low density lipoprotein receptor)
B: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
C: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
D: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
E: apolipoprotein b receptor (homo sapiens) (aka apolipoprotein b receptor)
F: None of the above. | F |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept corresponding to 'gp330'. Answer using one of the provided options. | <Options>: A: gp330 (homo sapiens) (aka ldl receptor related protein 2)
B: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s homeolog (xenopus laevis)) (aka provisional ortholog of zona pellucida glycoprotein 3 s homeolog)
C: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
D: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
E: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
F: None of the above. | A |
<Instruct>: Given the context 'The deduced amino acid sequence of this protein contains regions with homology to the human low density lipoprotein (LDL) receptor, an indication that GP330 and the LDL receptor may be members of the same gene family.', select the correct biomedical concept corresponding to 'ldl receptor'. Answer using one of the provided options. | <Options>: A: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
B: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
C: low density lipoprotein receptor (sus scrofa) (aka low density lipoprotein receptor)
D: lrp1 (homo sapiens) (ldl receptor related protein 1 (homo sapiens)) (aka ldl receptor related protein 1)
E: ldlr (homo sapiens) (aka low density lipoprotein receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept corresponding to 'gp330'. Answer using one of the provided options. | <Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
B: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
C: gp330 (mus musculus) (aka low density lipoprotein receptor-related protein 2)
D: gp43 (xenopus laevis) (provisional ortholog of zona pellucida glycoprotein 3 s homeolog (xenopus laevis)) (aka provisional ortholog of zona pellucida glycoprotein 3 s homeolog)
E: gp330 (homo sapiens) (aka ldl receptor related protein 2)
F: None of the above. | E |
<Instruct>: Given the context 'Autoantibodies from the kidneys of rats with Heymann nephritis reacted with a nonglycosylated segment of GP330 that contains cysteine-rich 40-amino acid repeats, which are also features of the LDL receptor.', select the correct biomedical concept corresponding to 'ldl receptor'. Answer using one of the provided options. | <Options>: A: low density lipoprotein receptor (homo sapiens) (aka low density lipoprotein receptor)
B: low density lipoprotein receptor (gallus gallus) (aka low density lipoprotein receptor)
C: very low density lipoprotein receptor (homo sapiens) (aka very low density lipoprotein receptor)
D: oxidized low density lipoprotein receptor 1 (homo sapiens) (aka oxidized low density lipoprotein receptor 1)
E: apolipoprotein b receptor (homo sapiens) (aka apolipoprotein b receptor)
F: None of the above. | A |
<Instruct>: Given the context 'GP330 is also similar in some regions to the mouse epidermal growth factor precursor.', select the correct biomedical concept corresponding to 'gp330'. Answer using one of the provided options. | <Options>: A: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 s homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 s homeolog)
B: gp330 (homo sapiens) (aka ldl receptor related protein 2)
C: gp340 (xenopus laevis) (deleted in malignant brain tumors 1 l homeolog (xenopus laevis)) (aka deleted in malignant brain tumors 1 l homeolog)
D: gp340 (xenopus tropicalis) (aka deleted in malignant brain tumors 1)
E: gp340 (homo sapiens) (aka deleted in malignant brain tumors 1)
F: None of the above. | B |
<Instruct>: Given the context 'Human mRNA polyadenylate binding protein: evolutionary conservation of a nucleic acid binding motif.
', select the correct biomedical concept corresponding to 'mrna polyadenylate binding protein'. Answer using one of the provided options. | <Options>: A: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
B: pabpn1 (homo sapiens) (aka poly(a) binding protein nuclear 1)
C: polyadenylate-binding protein (saccharomyces cerevisiae s288c) (aka polyadenylate-binding protein)
D: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
E: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
F: None of the above. | E |
<Instruct>: Given the context 'We have isolated a full length cDNA (cDNA) coding for the human poly(A) binding protein.', select the correct biomedical concept corresponding to 'poly(a) binding protein'. Answer using one of the provided options. | <Options>: A: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
B: poly(a) binding protein nuclear 1 (homo sapiens) (aka poly(a) binding protein nuclear 1)
C: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
D: poly(a) binding protein, cytoplasmic 1 (xenopus tropicalis) (aka poly(a) binding protein, cytoplasmic 1)
E: poly(a) binding protein cytoplasmic 1 (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
F: None of the above. | E |
<Instruct>: Given the context 'The cDNA derived 73 kd basic translation product has the same Mr, isoelectric point and peptidic map as the poly(A) binding protein.', select the correct biomedical concept corresponding to 'poly(a) binding protein'. Answer using one of the provided options. | <Options>: A: poly(a) binding protein nuclear 1 (homo sapiens) (aka poly(a) binding protein nuclear 1)
B: pabp (xenopus tropicalis) (poly(a) binding protein, cytoplasmic 1 (xenopus tropicalis)) (aka poly(a) binding protein, cytoplasmic 1)
C: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
D: poly(a) binding protein 1 (arabidopsis thaliana) (aka poly(a) binding protein 1)
E: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
F: None of the above. | C |
<Instruct>: Given the context 'The N terminal part, highly homologous to the yeast poly(A) binding protein, is sufficient for poly(A) binding activity.', select the correct biomedical concept corresponding to 'poly(a) binding protein'. Answer using one of the provided options. | <Options>: A: polyadenylate-binding protein 1 (arabidopsis thaliana) (aka polyadenylate-binding protein 1)
B: poly(a) binding protein, cytoplasmic 1 (xenopus tropicalis) (aka poly(a) binding protein, cytoplasmic 1)
C: poly(a) binding protein (drosophila melanogaster) (aka poly(a) binding protein)
D: pabp (homo sapiens) (aka poly(a) binding protein cytoplasmic 1)
E: poly(a)-binding protein (arabidopsis thaliana) (aka poly(a)-binding protein 5)
F: None of the above. | D |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept corresponding to 'c1'. Answer using one of the provided options. | <Options>: A: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
B: c1r (homo sapiens) (aka complement c1r)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: host cell factor c1 (bos taurus) (aka host cell factor c1)
E: hho.c1 (homo sapiens) (aka homeobox b7)
F: None of the above. | E |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept corresponding to 'c1'. Answer using one of the provided options. | <Options>: A: c1r (homo sapiens) (aka complement c1r)
B: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
C: host cell factor c1 (bos taurus) (aka host cell factor c1)
D: c1s (homo sapiens) (aka complement c1s)
E: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
F: None of the above. | F |
<Instruct>: Given the context 'Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development.
', select the correct biomedical concept corresponding to 'c8'. Answer using one of the provided options. | <Options>: A: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
B: g8 (homo sapiens) (aka small nucleolar rna host gene 32)
C: m8 (homo sapiens) (aka prion locus lncrna, testis expressed)
D: homeobox c8 (homo sapiens) (aka homeobox c8)
E: hho.c8 (homo sapiens) (aka homeobox c6)
F: None of the above. | D |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept corresponding to 'hho.c1'. Answer using one of the provided options. | <Options>: A: ch1 (homo sapiens) (aka sun domain containing ossification factor)
B: hho.c1 (homo sapiens) (aka homeobox b7)
C: hc1 (homo sapiens) (aka cycs pseudogene 39)
D: coh1 (homo sapiens) (aka vacuolar protein sorting 13 homolog b)
E: host cell factor c1 (homo sapiens) (aka host cell factor c1)
F: None of the above. | B |
<Instruct>: Given the context 'Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed.', select the correct biomedical concept corresponding to 'hho.c8'. Answer using one of the provided options. | <Options>: A: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: hha8 (homo sapiens) (aka keratin 38)
D: hox8 (homo sapiens) (aka msh homeobox 2)
E: c8c (homo sapiens) (aka complement c8 gamma chain)
F: None of the above. | B |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept corresponding to 'c1'. Answer using one of the provided options. | <Options>: A: c1s (homo sapiens) (aka complement c1s)
B: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
C: hho.c1 (homo sapiens) (aka homeobox b7)
D: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
E: c1in (homo sapiens) (aka serpin family g member 1)
F: None of the above. | C |
<Instruct>: Given the context 'Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development.', select the correct biomedical concept corresponding to 'c8'. Answer using one of the provided options. | <Options>: A: g8 (homo sapiens) (aka small nucleolar rna host gene 32)
B: hho.c8 (homo sapiens) (aka homeobox c6)
C: c8a (homo sapiens) (aka complement c8 alpha chain)
D: homeobox c8 (homo sapiens) (aka homeobox c8)
E: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
F: None of the above. | D |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept corresponding to 'hho.c1'. Answer using one of the provided options. | <Options>: A: hho.c1 (homo sapiens) (aka homeobox b7)
B: hho.c1 (xenopus tropicalis) (aka homeobox b7)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: hc1 (homo sapiens) (aka cycs pseudogene 39)
E: host cell factor c1 (homo sapiens) (aka host cell factor c1)
F: None of the above. | A |
<Instruct>: Given the context 'HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111', select the correct biomedical concept corresponding to 'hho.c8'. Answer using one of the provided options. | <Options>: A: hha8 (homo sapiens) (aka keratin 38)
B: hh8 (homo sapiens) (aka kiss1 receptor)
C: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
D: c8c (homo sapiens) (aka complement c8 gamma chain)
E: homeobox c8 (homo sapiens) (aka homeobox c8)
F: None of the above. | E |
<Instruct>: Given the context 'encodes a 153-amino acid protein containing a homeodomain identical to that of the frog AC1 gene.', select the correct biomedical concept corresponding to 'ac1'. Answer using one of the provided options. | <Options>: A: aconitate decarboxylase 1 (homo sapiens) (aka aconitate decarboxylase 1)
B: acc-1 (homo sapiens) (aka bcl2 related protein a1)
C: an1 (homo sapiens) (aka paired box 6)
D: acc1 (homo sapiens) (acetyl-coa carboxylase alpha (homo sapiens)) (aka acetyl-coa carboxylase alpha)
E: ach1 (homo sapiens) (aka acyl-coa thioesterase 7)
F: None of the above. | F |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept corresponding to 'hho.c1'. Answer using one of the provided options. | <Options>: A: hhc1 (homo sapiens) (aka calcium sensing receptor)
B: hho.c1 (homo sapiens) (aka homeobox b7)
C: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
D: host cell factor c1 (homo sapiens) (aka host cell factor c1)
E: ch1 (homo sapiens) (aka sun domain containing ossification factor)
F: None of the above. | B |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept corresponding to 'hho.c8'. Answer using one of the provided options. | <Options>: A: o8 (homo sapiens) (aka immunoglobulin kappa variable 1d-33)
B: c8c (homo sapiens) (aka complement c8 gamma chain)
C: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
D: hoxc8 (homo sapiens) (aka homeobox c8)
E: hh8 (homo sapiens) (aka kiss1 receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively.', select the correct biomedical concept corresponding to 'hho.c8'. Answer using one of the provided options. | <Options>: A: c8c (homo sapiens) (aka complement c8 gamma chain)
B: o8 (homo sapiens) (aka immunoglobulin kappa variable 1d-33)
C: atoh8 (homo sapiens) (aka atonal bhlh transcription factor 8)
D: hoxc8 (xenopus laevis) (homeobox c8 s homeolog (xenopus laevis)) (aka homeobox c8 s homeolog)
E: hh8 (homo sapiens) (aka kiss1 receptor)
F: None of the above. | F |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.', select the correct biomedical concept corresponding to 'c1'. Answer using one of the provided options. | <Options>: A: a-c1 (homo sapiens) (aka phospholipase a and acyltransferase 1)
B: hho.c1 (homo sapiens) (aka homeobox b7)
C: complement c1r (homo sapiens) (aka complement c1r)
D: c1_c (homo sapiens) (aka endogenous retrovirus group k member 18)
E: c1nh (homo sapiens) (aka serpin family g member 1)
F: None of the above. | B |
<Instruct>: Given the context 'These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes.', select the correct biomedical concept corresponding to 'c8'. Answer using one of the provided options. | <Options>: A: m8 (drosophila melanogaster) (enhancer of split m8, helix-loop-helix (drosophila melanogaster)) (aka enhancer of split m8, helix-loop-helix)
B: homeobox c8 (homo sapiens) (aka homeobox c8)
C: hho.c8 (homo sapiens) (aka homeobox c6)
D: scg8 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 1 inhibitor)
E: g8 (homo sapiens) (aka small nucleolar rna host gene 32)
F: None of the above. | B |
<Instruct>: Given the context 'Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.', select the correct biomedical concept corresponding to 'c1'. Answer using one of the provided options. | <Options>: A: c1s (homo sapiens) (aka complement c1s)
B: host cell factor c1 (bos taurus) (aka host cell factor c1)
C: c1_c (homo sapiens) (aka endogenous retrovirus group k member 18)
D: hho.c1 (homo sapiens) (aka homeobox b7)
E: c1_a (homo sapiens) (aka endogenous retrovirus group k member 1)
F: None of the above. | D |
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