instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (homo sapiens) (aka nerve growth factor)
B: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
C: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
D: ngfb (rattus norvegicus) (aka nerve growth factor)
E: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
F: None of the above. | A |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
B: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
C: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
D: ngfb (bos taurus) (aka nerve growth factor)
E: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
F: None of the above. | F |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
B: ngfb (rattus norvegicus) (aka nerve growth factor)
C: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
D: ngfb (bos taurus) (aka nerve growth factor)
E: beta-ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | E |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
B: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
C: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
D: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
E: beta-ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | F |
<Instruct>: Given the context 'Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
', select the correct biomedical concept corresponding to 'alpha subunit of the rod cgmp-gated channel'. Answer using one of the provided options. | <Options>: A: protein kinase camp-dependent type i regulatory subunit alpha (homo sapiens) (aka protein kinase camp-dependent type i regulatory subunit alpha)
B: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
C: cyclic nucleotide gated channel subunit alpha 1 (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 1)
D: achra (homo sapiens) (aka cholinergic receptor nicotinic alpha 1 subunit)
E: alpha1aar (homo sapiens) (aka adrenoceptor alpha 1a)
F: None of the above. | F |
<Instruct>: Given the context 'Mutations in the genes encoding two proteins of the retinal rod phototransduction cascade, opsin and the beta subunit of rod cGMP phosphodiesterase, cause retinitis pigmentosa (RP) in some families.', select the correct biomedical concept corresponding to 'beta subunit of rod cgmp phosphodiesterase'. Answer using one of the provided options. | <Options>: A: pde1b (homo sapiens) (aka phosphodiesterase 1b)
B: pde8b (homo sapiens) (aka phosphodiesterase 8b)
C: pdeb (homo sapiens) (aka phosphodiesterase 6b)
D: pdeivb (homo sapiens) (aka phosphodiesterase 4b)
E: phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus) (aka phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide)
F: None of the above. | C |
<Instruct>: Given the context 'Mutations in the genes encoding two proteins of the retinal rod phototransduction cascade, opsin and the beta subunit of rod cGMP phosphodiesterase, cause retinitis pigmentosa (RP) in some families.', select the correct biomedical concept corresponding to 'beta subunit of rod cgmp phosphodiesterase'. Answer using one of the provided options. | <Options>: A: pdeivb (homo sapiens) (aka phosphodiesterase 4b)
B: pde8b (homo sapiens) (aka phosphodiesterase 8b)
C: pdes1b (homo sapiens) (aka phosphodiesterase 1b)
D: phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus) (aka phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide)
E: pde3b (homo sapiens) (aka phosphodiesterase 3b)
F: None of the above. | F |
<Instruct>: Given the context 'We screened 94 unrelated patients with autosomal dominant RP and 173 unrelated patients with autosomal recessive RP for mutations in the gene encoding the alpha subunit of the rod cGMP-gated cation channel.', select the correct biomedical concept corresponding to 'alpha subunit of the rod cgmp-gated cation channel'. Answer using one of the provided options. | <Options>: A: cyclic nucleotide gated channel alpha 1 (xenopus tropicalis) (aka cyclic nucleotide gated channel alpha 1)
B: cgmp-gated cation channel alpha-1-like (rattus norvegicus) (aka cgmp-gated cation channel alpha-1-like)
C: cyclic nucleotide gated channel subunit alpha 1 (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 1)
D: cyclic nucleotide gated channel subunit alpha 2 (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 2)
E: achra (homo sapiens) (aka cholinergic receptor nicotinic alpha 1 subunit)
F: None of the above. | F |
<Instruct>: Given the context 'Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
', select the correct biomedical concept corresponding to 'cellular apoptosis susceptibility gene'. Answer using one of the provided options. | <Options>: A: cuta divalent cation tolerance homolog (sus scrofa) (aka cuta divalent cation tolerance homolog)
B: atherosclerosis susceptibility (lipoprotein associated) (homo sapiens) (aka atherosclerosis susceptibility (lipoprotein associated))
C: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
D: hearing loss, cisplatin-induced, susceptibility to (homo sapiens) (aka hearing loss, cisplatin-induced, susceptibility to)
E: cancer susceptibility 11 (homo sapiens) (aka cancer susceptibility 11)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
B: cse-c (homo sapiens) (aka sialic acid acetylesterase)
C: cse1 (homo sapiens) (aka chromosome segregation 1 like)
D: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
E: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
F: None of the above. | E |
<Instruct>: Given the context 'We report here that one of these fragments is an antisense fragment of a gene homologous to the essential yeast chromosome segregation gene CSE1.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
B: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
C: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
D: cse1l (homo sapiens) (aka chromosome segregation 1 like)
E: cse-c (homo sapiens) (aka sialic acid acetylesterase)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
B: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
C: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
D: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
E: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
B: casa (homo sapiens) (aka casein alpha s1)
C: cas (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
D: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
E: cas1 (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cellular apoptosis susceptibility gene'. Answer using one of the provided options. | <Options>: A: cas (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
B: ovarian cancer, epithelial, susceptibility to (homo sapiens) (aka ovarian cancer, epithelial, susceptibility to)
C: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
D: radiation sensitivity/chromosome instability syndrome, autosomal dominant (homo sapiens) (aka radiation sensitivity/chromosome instability syndrome, autosomal dominant)
E: caspr (homo sapiens) (aka contactin associated protein 1)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
B: casa (homo sapiens) (aka casein alpha s1)
C: casr (homo sapiens) (aka calcium sensing receptor)
D: cas (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
E: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
B: cse1 (homo sapiens) (aka chromosome segregation 1 like)
C: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
D: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
E: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
B: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
C: cse-c (homo sapiens) (aka sialic acid acetylesterase)
D: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
E: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
F: None of the above. | D |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: csec (homo sapiens) (aka sialic acid acetylesterase)
B: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
C: cse1 (homo sapiens) (aka chromosome segregation 1 like)
D: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
E: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
F: None of the above. | F |
<Instruct>: Given the context 'The conservation of this gene indicates it has an important function in human cells consistent with the essential role of CSE1 in yeast.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1l (homo sapiens) (aka chromosome segregation 1 like)
B: csec (homo sapiens) (aka sialic acid acetylesterase)
C: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
D: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
E: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
F: None of the above. | C |
<Instruct>: Given the context 'CAS is highly expressed in human tumor cell lines and in human testis and fetal liver, tissues that contain actively dividing cells.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas1 (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
B: casa (homo sapiens) (aka casein alpha s1)
C: casr (homo sapiens) (aka calcium sensing receptor)
D: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
E: bcar1 scaffold protein, cas family member (gallus gallus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | D |
<Instruct>: Given the context 'Furthermore, CAS expression increases when resting human fibroblasts are induced to proliferate and decreases when they are growth-arrested.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas1p (homo sapiens) (aka cas1 domain sialic acid o acetyltransferase 1)
B: bcar1 scaffold protein, cas family member (gallus gallus) (aka bcar1 scaffold protein, cas family member)
C: cas (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
D: casa (homo sapiens) (aka casein alpha s1)
E: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
F: None of the above. | E |
<Instruct>: Given the context 'Thus, CAS appears to play an important role in both toxin and tumor necrosis factor-mediated cell death, as well as in cell proliferation.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: casa (homo sapiens) (aka casein alpha s1)
B: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
C: bcar1 scaffold protein, cas family member (gallus gallus) (aka bcar1 scaffold protein, cas family member)
D: casr (homo sapiens) (aka calcium sensing receptor)
E: bcar1 scaffold protein, cas family member (homo sapiens) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | B |
<Instruct>: Given the context 'They were all located on the long arm of chromosome 17, in loci located between q11 and q21.3, a region known to contain the c-erbB-2 oncogene and the BRCA1 breast carcinomas, and overexpression of three of them was dependent on gene amplification in breast cancer cell lines.', select the correct biomedical concept corresponding to 'c-erbb-2'. Answer using one of the provided options. | <Options>: A: erbb3 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 3)
B: c-erb2 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: None of the above. | B |
<Instruct>: Given the context 'They were all located on the long arm of chromosome 17, in loci located between q11 and q21.3, a region known to contain the c-erbB-2 oncogene and the BRCA1 breast carcinomas, and overexpression of three of them was dependent on gene amplification in breast cancer cell lines.', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
B: brcaa1 (homo sapiens) (aka at-rich interaction domain 4b)
C: brca1 promoter region (homo sapiens) (aka brca1 promoter region)
D: pseudo-brca1 (homo sapiens) (aka brca1 pseudogene 1)
E: brca1 dna repair associated (homo sapiens) (aka brca1 dna repair associated)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.
', select the correct biomedical concept corresponding to 'striatum-enriched phosphatase'. Answer using one of the provided options. | <Options>: A: ptpe (homo sapiens) (aka protein tyrosine phosphatase receptor type e)
B: ctd small phosphatase like (sus scrofa) (aka ctd small phosphatase like)
C: phosphoethanolamine/phosphocholine phosphatase (sus scrofa) (aka phosphoethanolamine/phosphocholine phosphatase)
D: ptpstep (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
E: ec-ptp (homo sapiens) (aka protein tyrosine phosphatase receptor type r)
F: None of the above. | D |
<Instruct>: Given the context 'Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.
', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: try (sus scrofa) (aka serine protease 2)
B: stp-1 (sus scrofa) (aka transition protein 1)
C: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
D: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
E: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
F: None of the above. | C |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step (drosophila melanogaster) (aka steppke)
B: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
C: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
D: try (sus scrofa) (aka serine protease 2)
E: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
F: None of the above. | B |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
B: try (sus scrofa) (aka serine protease 2)
C: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
D: stp-1 (sus scrofa) (aka transition protein 1)
E: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
F: None of the above. | A |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
B: step (drosophila melanogaster) (aka steppke)
C: try (sus scrofa) (aka serine protease 2)
D: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
E: tptep (homo sapiens) (aka tpte2 pseudogene 4)
F: None of the above. | F |
<Instruct>: Given the context 'These are two regions of known conserved synteny, providing further evidence that the human STEP is a true homolog of the murine STEP gene.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
B: try (sus scrofa) (aka serine protease 2)
C: tptep (homo sapiens) (aka tpte2 pseudogene 4)
D: step (drosophila melanogaster) (aka steppke)
E: step61 (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
F: None of the above. | E |
<Instruct>: Given the context 'These are two regions of known conserved synteny, providing further evidence that the human STEP is a true homolog of the murine STEP gene.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
B: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
C: try (sus scrofa) (aka serine protease 2)
D: step (drosophila melanogaster) (aka steppke)
E: tptep (homo sapiens) (aka tpte2 pseudogene 4)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2.
', select the correct biomedical concept corresponding to 'atp synthase oscp subunit'. Answer using one of the provided options. | <Options>: A: atp synthase peripheral stalk subunit oscp (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
B: atp synthase subunit o, mitochondrial (caenorhabditis elegans) (aka atp synthase subunit o, mitochondrial)
C: atp synthase peripheral stalk subunit oscp (oryctolagus cuniculus) (aka atp synthase peripheral stalk subunit oscp)
D: atpo (xenopus laevis) (atp synthase peripheral stalk subunit oscp s homeolog (xenopus laevis)) (aka atp synthase peripheral stalk subunit oscp s homeolog)
E: atp synthase peripheral stalk subunit oscp (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2.
', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5o (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
B: atp5e (homo sapiens) (aka atp synthase f1 subunit epsilon)
C: atp5lp5 (homo sapiens) (aka atp synthase membrane subunit g pseudogene 5)
D: atp5i (homo sapiens) (aka atp synthase membrane subunit e)
E: atp5o (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
F: None of the above. | A |
<Instruct>: Given the context 'We subsequently cloned the full-length human ATP synthase OSCP cDNA (GDB/HGMW approved name ATP50) from infant brain and muscle libraries and determined its nucleotide and deduced amino acid sequence (EMBL/GenBank Accession No. X83218).', select the correct biomedical concept corresponding to 'atp synthase oscp'. Answer using one of the provided options. | <Options>: A: atp synthase peripheral stalk subunit oscp (xenopus tropicalis) (aka atp synthase peripheral stalk subunit oscp)
B: atp synthase peripheral stalk subunit oscp (oryctolagus cuniculus) (aka atp synthase peripheral stalk subunit oscp)
C: oscp (homo sapiens) (atp synthase peripheral stalk subunit oscp (homo sapiens)) (aka atp synthase peripheral stalk subunit oscp)
D: atp5s (oryctolagus cuniculus) (aka distal membrane arm assembly component 2 like)
E: atp synthase subunit o, mitochondrial (caenorhabditis elegans) (aka atp synthase subunit o, mitochondrial)
F: None of the above. | C |
<Instruct>: Given the context 'We subsequently cloned the full-length human ATP synthase OSCP cDNA (GDB/HGMW approved name ATP50) from infant brain and muscle libraries and determined its nucleotide and deduced amino acid sequence (EMBL/GenBank Accession No. X83218).', select the correct biomedical concept corresponding to 'atp50'. Answer using one of the provided options. | <Options>: A: atp20 (saccharomyces cerevisiae s288c) (aka f1f0 atp synthase subunit g)
B: translocase of inner mitochondrial membrane 50 homolog (xenopus tropicalis) (aka translocase of inner mitochondrial membrane 50 homolog)
C: atpa (escherichia coli str. k-12 substr. mg1655) (aka atp synthase f1 complex subunit alpha)
D: atpo (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
E: transmembrane protein 50 homolog (glycine max) (aka transmembrane protein 50 homolog)
F: None of the above. | D |
<Instruct>: Given the context 'The human ATP5O gene is located at 21q22.1-q22.2, just proximal to D21S17, in YACs 860G11 and 838C7 of the Chumakov et al.', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5o (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
B: atp5 (homo sapiens) (aka atp synthase peripheral stalk subunit f6)
C: atp5lp5 (homo sapiens) (aka atp synthase membrane subunit g pseudogene 5)
D: atp5i (homo sapiens) (aka atp synthase membrane subunit e)
E: atp5po (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
F: None of the above. | E |
<Instruct>: Given the context 'This ATP5O subunit is a key structural component of the stalk of the mitochondrial respiratory chain F1F0-ATP synthase and as such may contribute in a gene dosage-dependent manner to the phenotype of Down syndrome (trisomy 21).', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5o (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
B: atp5o (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
C: atp5l (homo sapiens) (aka atp synthase membrane subunit g)
D: atp5 (homo sapiens) (aka atp synthase peripheral stalk subunit f6)
E: atp5lp5 (homo sapiens) (aka atp synthase membrane subunit g pseudogene 5)
F: None of the above. | B |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
B: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
C: ca7.5 (mus musculus) (aka dna segment, ca7.5)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
F: None of the above. | B |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'mitochondrial carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
B: carbonic anhydrase 5a, mitochondrial-like (homo sapiens) (aka carbonic anhydrase 5a, mitochondrial-like)
C: carbonic anhydrase 5a, mitochondrial (mus musculus) (aka carbonic anhydrase 5a, mitochondrial)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
F: None of the above. | E |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'mitochondrial carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5a, mitochondrial (mus musculus) (aka carbonic anhydrase 5a, mitochondrial)
B: carbonic anhydrase vb, mitochondrial (xenopus tropicalis) (aka carbonic anhydrase vb, mitochondrial)
C: ca-xiv (mus musculus) (aka carbonic anhydrase 14)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: carbonic anhydrase 5a, mitochondrial-like (homo sapiens) (aka carbonic anhydrase 5a, mitochondrial-like)
F: None of the above. | F |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
B: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
C: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
D: carbonic anhydrase 5a, mitochondrial-like (homo sapiens) (aka carbonic anhydrase 5a, mitochondrial-like)
E: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
B: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
C: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'It is of interest for its putative roles in providing bicarbonate to carbamoyl phosphate synthetase for ureagenesis and to pyruvate carboxylase for gluconeogenesis and its possible importance in explaining certain inherited metabolic disorders with hyperammonemia and hypoglycemia.', select the correct biomedical concept corresponding to 'pyruvate carboxylase'. Answer using one of the provided options. | <Options>: A: pc (homo sapiens) (pyruvate carboxylase (homo sapiens)) (aka pyruvate carboxylase)
B: pyruvate carboxylase (sus scrofa) (aka pyruvate carboxylase)
C: pc (oryctolagus cuniculus) (pyruvate carboxylase (oryctolagus cuniculus)) (aka pyruvate carboxylase)
D: pyruvate carboxylase 1 (saccharomyces cerevisiae s288c) (aka pyruvate carboxylase 1)
E: pyruvate carboxylase (xenopus tropicalis) (aka pyruvate carboxylase)
F: None of the above. | A |
<Instruct>: Given the context 'Following the recent characterization of the cDNA for human CA V, we report the isolation of the human gene from two lambda genomic libraries and its characterization.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
B: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
C: coagulation factor v (homo sapiens) (aka coagulation factor v)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
F: None of the above. | B |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
B: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
C: cav (homo sapiens) (carbonic anhydrase 5a (homo sapiens)) (aka carbonic anhydrase 5a)
D: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
E: coagulation factor v (homo sapiens) (aka coagulation factor v)
F: None of the above. | C |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
B: ca5d (homo sapiens) (aka carbonic anhydrase 5a)
C: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
D: ca7.5 (mus musculus) (aka dna segment, ca7.5)
E: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
F: None of the above. | B |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca ii'. Answer using one of the provided options. | <Options>: A: caiii (homo sapiens) (aka carbonic anhydrase 3)
B: ca-rp ii (homo sapiens) (aka carbonic anhydrase 11)
C: cai2 (homo sapiens) (aka cyclin dependent kinase inhibitor 2a)
D: carbonic anhydrase 2 (homo sapiens) (aka carbonic anhydrase 2)
E: ca-2 (xenopus laevis) (carbonic anhydrase 2 s homeolog (xenopus laevis)) (aka carbonic anhydrase 2 s homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca iii'. Answer using one of the provided options. | <Options>: A: ac-iii (homo sapiens) (aka adenylate cyclase 3)
B: carbonic anhydrase 3 (homo sapiens) (aka carbonic anhydrase 3)
C: ca(v)3.3 (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 i)
D: carbonic anhydrase i (xenopus tropicalis) (aka carbonic anhydrase i)
E: carbonic anhydrase 3a (gallus gallus) (aka carbonic anhydrase 3a)
F: None of the above. | B |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: ca7 (gallus gallus) (aka carbonic anhydrase 7)
B: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
C: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
D: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
E: ca7 (homo sapiens) (aka carbonic anhydrase 7)
F: None of the above. | E |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: ca7 (gallus gallus) (aka carbonic anhydrase 7)
B: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
C: carbonic anhydrase 7 (homo sapiens) (aka carbonic anhydrase 7)
D: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
E: ca7 (xenopus tropicalis) (aka carbonic anhydrase vii)
F: None of the above. | C |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
B: ca7 (xenopus tropicalis) (aka carbonic anhydrase vii)
C: ca7 (gallus gallus) (aka carbonic anhydrase 7)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
F: None of the above. | F |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
B: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
C: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
D: ca7.5 (mus musculus) (aka dna segment, ca7.5)
E: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
F: None of the above. | C |
<Instruct>: Given the context 'CA5 also contains a 12-bp GT-rich segment beginning 13 bp downstream of the polyadenylation signal in the 3' untranslated region of exon 7.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: ca7.5 (mus musculus) (aka dna segment, ca7.5)
B: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
C: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
D: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
E: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
F: None of the above. | B |
<Instruct>: Given the context 'FISH analysis allowed CA5 to be assigned to chromosome 16q24.3.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
B: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
C: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
D: ca7.5 (mus musculus) (aka dna segment, ca7.5)
E: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
F: None of the above. | B |
<Instruct>: Given the context 'Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21.
', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans) (aka breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1)
B: brcaa1 (homo sapiens) (aka at-rich interaction domain 4b)
C: brca1 (homo sapiens) (aka brca1 dna repair associated)
D: brca1 pseudogene 1 (homo sapiens) (aka brca1 pseudogene 1)
E: brca1 promoter region (homo sapiens) (aka brca1 promoter region)
F: None of the above. | C |
<Instruct>: Given the context 'Fragments corresponding to the broadly expressed gamma-tubulin and Ki antigen genes were identified.', select the correct biomedical concept corresponding to 'ki antigen'. Answer using one of the provided options. | <Options>: A: ki (homo sapiens) (aka proteasome activator subunit 3)
B: marker of proliferation ki-67 (gallus gallus) (aka marker of proliferation ki-67)
C: ki-1 (homo sapiens) (aka tnf receptor superfamily member 8)
D: marker of proliferation ki-67 (xenopus tropicalis) (aka marker of proliferation ki-67)
E: kia (homo sapiens) (aka marker of proliferation ki-67)
F: None of the above. | A |
<Instruct>: Given the context 'A full-length cDNA clone encoding a 117-amino-acid protein homologous to the rat ribosomal protein L34 was isolated.', select the correct biomedical concept corresponding to 'ribosomal protein l34'. Answer using one of the provided options. | <Options>: A: ribosomal protein l34 (gallus gallus) (aka ribosomal protein l34)
B: l34 (drosophila melanogaster) (ribosomal protein l34a (drosophila melanogaster)) (aka ribosomal protein l34a)
C: l34 (xenopus laevis) (ribosomal protein l34 l homeolog (xenopus laevis)) (aka ribosomal protein l34 l homeolog)
D: ribosomal protein l34 (xenopus tropicalis) (aka ribosomal protein l34)
E: ribosomal protein l34 (mus musculus) (aka ribosomal protein l34)
F: None of the above. | F |
<Instruct>: Given the context 'Portions of genes with restricted patterns of expression were also obtained, including the previously characterized HSD17B1.', select the correct biomedical concept corresponding to 'hsd17b1'. Answer using one of the provided options. | <Options>: A: hsd17b1 (sus scrofa) (aka hydroxysteroid 17-beta dehydrogenase 1)
B: hsd11b1 (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
C: hydroxysteroid 17-beta dehydrogenase 1 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 1)
D: hsd17b1p1 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 1 pseudogene 1)
E: hsd17b3 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 3)
F: None of the above. | C |
<Instruct>: Given the context 'A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing.
', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: None of the above. | C |
<Instruct>: Given the context 'We report here a novel K+ channel beta-subunit cloned from human heart, hKv beta 1.3, that has 74-83% overall identity with previously cloned beta-subunits.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: None of the above. | D |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: None of the above. | A |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: None of the above. | D |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 3'. Answer using one of the provided options. | <Options>: A: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: kv-beta-3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 3)
C: slo-beta-3 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 3)
D: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
E: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
F: None of the above. | D |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'rkv beta 1'. Answer using one of the provided options. | <Options>: A: similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)) (rattus norvegicus) (aka similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)))
B: potassium voltage-gated channel subfamily a regulatory beta subunit 1 (rattus norvegicus) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
C: k(vca)beta-1 (rattus norvegicus) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 1)
D: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: potassium channel, voltage gated subfamily a regulatory beta subunit 1 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
F: None of the above. | B |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
D: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: None of the above. | D |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv1.5'. Answer using one of the provided options. | <Options>: A: kv5.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily f member 1)
B: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
C: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 s homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 s homeolog)
D: kv1.5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
E: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: None of the above. | D |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: hkvb3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
E: None of the above. | C |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept corresponding to 'kv1.5'. Answer using one of the provided options. | <Options>: A: kcnk5 (homo sapiens) (aka potassium two pore domain channel subfamily k member 5)
B: kv1.5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
C: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
D: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
E: kv5.1 (homo sapiens) (aka potassium voltage-gated channel modifier subfamily f member 1)
F: None of the above. | B |
<Instruct>: Given the context 'De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III).
', select the correct biomedical concept corresponding to 'myelin p0'. Answer using one of the provided options. | <Options>: A: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
B: ribosomal protein lateral stalk subunit p0 (mus musculus) (aka ribosomal protein lateral stalk subunit p0)
C: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
D: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
E: myelin protein zero (mus musculus) (aka myelin protein zero)
F: None of the above. | D |
<Instruct>: Given the context 'We have investigated the myelin P0 gene on chromosome 1 as a candidate gene in two sporadic cases with Dejerine-Sottas disease or hereditary motor and sensory neuropathy (HMSN) type III.', select the correct biomedical concept corresponding to 'myelin p0'. Answer using one of the provided options. | <Options>: A: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
B: ribosomal protein lateral stalk subunit p0 (mus musculus) (aka ribosomal protein lateral stalk subunit p0)
C: myelin protein zero-like 1 (rattus norvegicus) (aka myelin protein zero-like 1)
D: myelin protein zero (mus musculus) (aka myelin protein zero)
E: myelin protein zero (homo sapiens) (aka myelin protein zero)
F: None of the above. | E |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept corresponding to 'p0'. Answer using one of the provided options. | <Options>: A: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
B: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
C: p0 (mus musculus) (aka myelin protein zero)
D: ribosomal protein, large, p0 (xenopus tropicalis) (aka ribosomal protein, large, p0)
E: ribosomal protein lateral stalk subunit p0 (homo sapiens) (aka ribosomal protein lateral stalk subunit p0)
F: None of the above. | A |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept corresponding to 'p0'. Answer using one of the provided options. | <Options>: A: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
B: ribosomal protein, large, p0 (xenopus tropicalis) (aka ribosomal protein, large, p0)
C: prlp0 (xenopus laevis) (ribosomal protein, large, p0 s homeolog (xenopus laevis)) (aka ribosomal protein, large, p0 s homeolog)
D: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
E: p0 (mus musculus) (aka myelin protein zero)
F: None of the above. | F |
<Instruct>: Given the context 'Human serum biotinidase.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
B: biotinidase (bos taurus) (aka biotinidase)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (homo sapiens) (aka biotinidase)
E: biotinidase (xenopus tropicalis) (aka biotinidase)
F: None of the above. | D |
<Instruct>: Given the context 'cDNA cloning, sequence, and characterization.
Biotinidase (EC 3.5.1.12) catalyzes the hydrolysis of biocytin, the product of biotin-dependent carboxylase degradation, to biotin and lysine.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
B: biotinidase (xenopus tropicalis) (aka biotinidase)
C: biotinase (bos taurus) (aka biotinidase)
D: biotinidase (homo sapiens) (aka biotinidase)
E: biotinidase (oryctolagus cuniculus) (aka biotinidase)
F: None of the above. | D |
<Instruct>: Given the context 'Biotinidase deficiency is an inherited metabolic disorder of biotin recycling that is characterized by neurological and cutaneous abnormalities, and can be successfully treated with biotin supplementation.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (oryctolagus cuniculus) (aka biotinidase)
B: biotinidase (sus scrofa) (aka biotinidase)
C: biotinase (bos taurus) (aka biotinidase)
D: biotinidase (xenopus tropicalis) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | E |
<Instruct>: Given the context 'Sequences of tryptic peptides of the purified human serum enzyme were used to design oligonucleotide primers for polymerase chain reaction amplification from human hepatic total RNA to generate putative biotinidase cDNA fragments.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
C: biotinidase (homo sapiens) (aka biotinidase)
D: biotinidase (bos taurus) (aka biotinidase)
E: biotinidase (xenopus tropicalis) (aka biotinidase)
F: None of the above. | C |
<Instruct>: Given the context 'Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (xenopus tropicalis) (aka biotinidase)
B: biotinidase (rattus norvegicus) (aka biotinidase)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (homo sapiens) (aka biotinidase)
E: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (oryctolagus cuniculus) (aka biotinidase)
B: biotinidase (sus scrofa) (aka biotinidase)
C: biotinidase (rattus norvegicus) (aka biotinidase)
D: biotinidase (xenopus tropicalis) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | E |
<Instruct>: Given the context 'Southern analyses suggested that biotinidase is a single copy gene and revealed that human cDNA probes hybridized to genomic DNA from mammals, but not from chicken or yeast.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (gallus gallus) (aka biotinidase)
B: biotinidase (homo sapiens) (aka biotinidase)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (mus musculus) (aka biotinidase)
E: biotinidase (xenopus tropicalis) (aka biotinidase)
F: None of the above. | B |
<Instruct>: Given the context 'Northern analysis indicated the presence of biotinidase mRNA in human heart, brain, placenta, liver, lung, skeletal muscle, kidney, and pancreas.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (xenopus tropicalis) (aka biotinidase)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | E |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
B: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
C: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
D: c1qg (homo sapiens) (aka complement c1q c chain)
E: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
F: None of the above. | A |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: crk (homo sapiens) (aka crk proto-oncogene, adaptor protein)
B: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
C: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
D: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
E: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
F: None of the above. | A |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
B: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
C: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
D: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
E: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
F: None of the above. | F |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'grb2'. Answer using one of the provided options. | <Options>: A: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
B: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
C: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
D: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
E: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
F: None of the above. | B |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'ash'. Answer using one of the provided options. | <Options>: A: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
B: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
C: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
D: ash (homo sapiens) (aka growth factor receptor bound protein 2)
E: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
F: None of the above. | D |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
B: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
C: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
D: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
E: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
F: None of the above. | D |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'grb2'. Answer using one of the provided options. | <Options>: A: grb2 associated binding protein 2 (homo sapiens) (aka grb2 associated binding protein 2)
B: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
C: egfrbp-grb2 (homo sapiens) (aka growth factor receptor bound protein 2)
D: grb2l (homo sapiens) (aka grb2 related adaptor protein 2)
E: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
F: None of the above. | C |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'ash'. Answer using one of the provided options. | <Options>: A: ash1-related 1 (arabidopsis thaliana) (aka set domain group 37)
B: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
C: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
D: ash (homo sapiens) (aka growth factor receptor bound protein 2)
E: ash (drosophila melanogaster) (aka absent, small, or homeotic discs 1)
F: None of the above. | D |
<Instruct>: Given the context 'Here another guanine nucleotide-releasing protein (GNRP), C3G, has been identified as a CRK SH3-binding protein.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
B: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
C: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
D: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
E: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
F: None of the above. | C |
<Instruct>: Given the context 'Here another guanine nucleotide-releasing protein (GNRP), C3G, has been identified as a CRK SH3-binding protein.', select the correct biomedical concept corresponding to 'crk sh3-binding protein'. Answer using one of the provided options. | <Options>: A: v-crk avian sarcoma virus ct10 oncogene homolog-like (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog-like)
B: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
C: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
D: crk like proto-oncogene, adaptor protein (homo sapiens) (aka crk like proto-oncogene, adaptor protein)
E: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
F: None of the above. | F |
<Instruct>: Given the context 'The nucleotide sequence of a 4.1-kb C3G cDNA contains a 3.2-kb open reading frame encoding a 121-kDa protein, and antibodies against C3G have been shown to detect a protein of 130-140 kDa.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c1qg (homo sapiens) (aka complement c1q c chain)
B: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
C: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
D: c3 (homo sapiens) (aka complement c3)
E: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
F: None of the above. | E |
<Instruct>: Given the context 'The nucleotide sequence of a 4.1-kb C3G cDNA contains a 3.2-kb open reading frame encoding a 121-kDa protein, and antibodies against C3G have been shown to detect a protein of 130-140 kDa.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
B: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
C: c1qg (homo sapiens) (aka complement c1q c chain)
D: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
E: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
F: None of the above. | D |
<Instruct>: Given the context 'The carboxyl terminus of C3G has a peptide sequence homologous to GNRPs for Ras, and the expression of this carboxyl terminus region suppresses the loss of CDC25 function in the yeast Saccharomyces cerevisiae.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c3g (drosophila melanogaster) (c3g guanyl-nucleotide exchange factor (drosophila melanogaster)) (aka c3g guanyl-nucleotide exchange factor)
B: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
C: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
D: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
E: c1qg (homo sapiens) (aka complement c1q c chain)
F: None of the above. | B |
<Instruct>: Given the context 'The carboxyl terminus of C3G has a peptide sequence homologous to GNRPs for Ras, and the expression of this carboxyl terminus region suppresses the loss of CDC25 function in the yeast Saccharomyces cerevisiae.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
B: complement c3 (homo sapiens) (aka complement c3)
C: c1qg (homo sapiens) (aka complement c1q c chain)
D: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
E: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
F: None of the above. | F |
<Instruct>: Given the context 'The carboxyl terminus of C3G has a peptide sequence homologous to GNRPs for Ras, and the expression of this carboxyl terminus region suppresses the loss of CDC25 function in the yeast Saccharomyces cerevisiae.', select the correct biomedical concept corresponding to 'cdc25'. Answer using one of the provided options. | <Options>: A: cdc25d (xenopus laevis) (provisional ortholog of cell division cycle 25c s homeolog (xenopus laevis)) (aka provisional ortholog of cell division cycle 25c s homeolog)
B: cdc25a (homo sapiens) (aka cell division cycle 25a)
C: cdc25 (saccharomyces cerevisiae s288c) (aka ras family guanine nucleotide exchange factor cdc25)
D: cdc25 (xenopus laevis) (cell division cycle 25c l homeolog (xenopus laevis)) (aka cell division cycle 25c l homeolog)
E: cdc25 (homo sapiens) (cell division cycle 25c (homo sapiens)) (aka cell division cycle 25c)
F: None of the above. | C |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: c1qg (homo sapiens) (aka complement c1q c chain)
B: c3g (rattus norvegicus) (aka rap guanine nucleotide exchange factor 1)
C: c3 (homo sapiens) (aka complement c3)
D: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
E: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
F: None of the above. | E |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
B: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
C: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
D: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
E: crk (homo sapiens) (aka crk proto-oncogene, adaptor protein)
F: None of the above. | E |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept corresponding to 'grb2'. Answer using one of the provided options. | <Options>: A: grb2 related adaptor protein (homo sapiens) (aka grb2 related adaptor protein)
B: gab2 (homo sapiens) (aka grb2 associated binding protein 2)
C: grb2 (bos taurus) (aka growth factor receptor bound protein 2)
D: growth factor receptor bound protein 2 (homo sapiens) (aka growth factor receptor bound protein 2)
E: grb2-b (xenopus tropicalis) (aka growth factor receptor bound protein 2)
F: None of the above. | D |
<Instruct>: Given the context 'The C3G protein expressed in Escherichia coli binds to CRK and GRB2/ASH proteins.', select the correct biomedical concept corresponding to 'ash'. Answer using one of the provided options. | <Options>: A: ash1 (absent, small, or homeotic)-like s homeolog (xenopus laevis) (aka ash1 (absent, small, or homeotic)-like s homeolog)
B: ash1 related protein 1 (arabidopsis thaliana) (aka set domain group 26)
C: ashr1 (arabidopsis thaliana) (aka set domain group 37)
D: ash (homo sapiens) (aka growth factor receptor bound protein 2)
E: arabidopsis ash2 relative (arabidopsis thaliana) (aka trauco)
F: None of the above. | D |
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