instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
B: arr2 (homo sapiens) (aka arrestin beta 2)
C: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
D: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
E: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
F: None of the above. | B |
<Instruct>: Given the context 'Confocal microscopy demonstrates the translocation of betaarr2-GFP to more than 15 different ligand-activated GPCRs.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
B: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
C: arb2 (homo sapiens) (arrestin beta 2 (homo sapiens)) (aka arrestin beta 2)
D: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
E: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
F: None of the above. | C |
<Instruct>: Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: arr2 (homo sapiens) (aka arrestin beta 2)
B: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
C: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
D: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
E: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
F: None of the above. | A |
<Instruct>: Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: arrestin, beta 2, pseudogene (rattus norvegicus) (aka arrestin, beta 2, pseudogene)
B: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
C: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
D: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
E: None of the above. | E |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hepatocyte growth factor activator inhibitor type 2'. Answer using one of the provided options. | <Options>: A: serpina2 (homo sapiens) (aka serpin family a member 2 (gene/pseudogene))
B: pai-2 (homo sapiens) (aka serpin family b member 2)
C: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
D: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: serine peptidase inhibitor kazal type 2 (homo sapiens) (aka serine peptidase inhibitor kazal type 2)
F: None of the above. | D |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hepatocyte growth factor (hgf) activator'. Answer using one of the provided options. | <Options>: A: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
B: hgf activator (homo sapiens) (aka hgf activator)
C: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
D: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
E: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
F: None of the above. | B |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
B: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
C: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
D: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
E: hgfa (homo sapiens) (aka hgf activator)
F: None of the above. | B |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
B: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
C: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
D: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
E: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
F: None of the above. | A |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hgfac (homo sapiens) (aka hgf activator)
B: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
C: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
D: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
E: hgf activator (sus scrofa) (aka hgf activator)
F: None of the above. | A |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator inhibitor type 1'. Answer using one of the provided options. | <Options>: A: agti (homo sapiens) (aka agouti signaling protein)
B: hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens) (aka hypoxia inducible factor 1 subunit alpha inhibitor)
C: protein inhibitor of activated stat 1 (homo sapiens) (aka protein inhibitor of activated stat 1)
D: pai-1 (homo sapiens) (aka serpin family e member 1)
E: serine peptidase inhibitor, kunitz type 1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | E |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
B: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
C: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
D: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
E: haik1 (homo sapiens) (aka keratin 23)
F: None of the above. | A |
<Instruct>: Given the context 'HAI-1 is a novel member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
B: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
C: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
D: haik1 (homo sapiens) (aka keratin 23)
E: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | B |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
B: hgfac (homo sapiens) (aka hgf activator)
C: hgf activator (sus scrofa) (aka hgf activator)
D: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
E: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
F: None of the above. | B |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
B: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: serpinf2 (homo sapiens) (aka serpin family f member 2)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
F: None of the above. | B |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: serpinf2 (homo sapiens) (aka serpin family f member 2)
B: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
C: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
D: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
E: iti-hc2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
F: None of the above. | F |
<Instruct>: Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: iti-hc2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
B: serpinf2 (homo sapiens) (aka serpin family f member 2)
C: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
D: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
F: None of the above. | D |
<Instruct>: Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
B: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: itih2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
D: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
E: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
F: None of the above. | B |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: serpinf2 (homo sapiens) (aka serpin family f member 2)
C: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
F: None of the above. | C |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
B: haik1 (homo sapiens) (aka keratin 23)
C: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
D: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
E: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | A |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
B: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: serpinf2 (homo sapiens) (aka serpin family f member 2)
D: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
E: iti-hc2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
F: None of the above. | B |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
B: serpinf2 (homo sapiens) (aka serpin family f member 2)
C: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
D: iti-hc2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
E: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
F: None of the above. | E |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
B: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
C: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
D: haik1 (homo sapiens) (aka keratin 23)
E: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | C |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hgf activator (sus scrofa) (aka hgf activator)
B: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
C: hgf activator (homo sapiens) (aka hgf activator)
D: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
E: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
F: None of the above. | C |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
B: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
C: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
D: hgf activator (homo sapiens) (aka hgf activator)
E: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
F: None of the above. | A |
<Instruct>: Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (gallus gallus) (aka glycogenin 2)
B: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
E: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
F: None of the above. | C |
<Instruct>: Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (sus scrofa) (aka glycogenin 2)
B: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
C: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
D: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
E: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
F: None of the above. | F |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (gallus gallus) (aka glycogenin 2)
B: glycogenin 2 (homo sapiens) (aka glycogenin 2)
C: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
D: glycogenin 2 (sus scrofa) (aka glycogenin 2)
E: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
F: None of the above. | B |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
C: gn2 (homo sapiens) (aka glycogenin 2)
D: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
E: gnl2 (homo sapiens) (aka g protein nucleolar 2)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
B: glycogenin 2 (homo sapiens) (aka glycogenin 2)
C: glycogenin 2 (bos taurus) (aka glycogenin 2)
D: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
E: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2alpha'. Answer using one of the provided options. | <Options>: A: gnb2 (homo sapiens) (aka g protein subunit beta 2)
B: gn2 (homo sapiens) (aka glycogenin 2)
C: gnai2a (homo sapiens) (aka g protein subunit alpha i2 pseudogene 1)
D: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
E: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2beta'. Answer using one of the provided options. | <Options>: A: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
B: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
C: gng2 (homo sapiens) (aka g protein subunit gamma 2)
D: gnl2 (homo sapiens) (aka g protein nucleolar 2)
E: gn2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2gamma'. Answer using one of the provided options. | <Options>: A: gnl2 (homo sapiens) (aka g protein nucleolar 2)
B: guanine nucleotide binding protein (g protein), gamma 2 (xenopus tropicalis) (aka guanine nucleotide binding protein (g protein), gamma 2)
C: g protein subunit gamma transducin 2 (homo sapiens) (aka g protein subunit gamma transducin 2)
D: gn-2 (homo sapiens) (aka glycogenin 2)
E: gng2 (homo sapiens) (aka g protein subunit gamma 2)
F: None of the above. | D |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
C: gng2 (homo sapiens) (aka g protein subunit gamma 2)
D: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
E: gn-2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept corresponding to 'muscle glycogenin'. Answer using one of the provided options. | <Options>: A: glycogenin 1 (gallus gallus) (aka glycogenin 1)
B: glycogenin 1 (homo sapiens) (aka glycogenin 1)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
E: muscle glycogen phosphorylase (mus musculus) (aka muscle glycogen phosphorylase)
F: None of the above. | B |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gng2 (homo sapiens) (aka g protein subunit gamma 2)
B: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
C: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
D: gn-2 (homo sapiens) (aka glycogenin 2)
E: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
F: None of the above. | D |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gnb2 (homo sapiens) (aka g protein subunit beta 2)
B: gng2 (homo sapiens) (aka g protein subunit gamma 2)
C: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
D: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
E: gn2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
B: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
C: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
D: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
E: gng2 (homo sapiens) (aka g protein subunit gamma 2)
F: None of the above. | F |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'skeletal muscle glycogen synthase'. Answer using one of the provided options. | <Options>: A: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
B: glycogen synthase 2 (mus musculus) (aka glycogen synthase 2)
C: glycogenin 1 (mus musculus) (aka glycogenin 1)
D: glycogen synthase 1 (muscle) (gallus gallus) (aka glycogen synthase 1 (muscle))
E: glycogen synthase 1 (xenopus tropicalis) (aka glycogen synthase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Antibodies raised against GN-2 produced in E. coli recognized proteins of Mr approximately 66,000 present in extracts of rat liver and in cultured H4IIEC3 hepatoma cells.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
B: gn2 (homo sapiens) (aka glycogenin 2)
C: gnb2 (homo sapiens) (aka g protein subunit beta 2)
D: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
E: gng2 (homo sapiens) (aka g protein subunit gamma 2)
F: None of the above. | B |
<Instruct>: Given the context 'In H4IIEC3 cells, most of the GN-2 was present as a free protein but some was covalently associated with glycogen fractions and was only released by treatment with alpha-amylase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gn2 (homo sapiens) (aka glycogenin 2)
B: g protein nucleolar 2 (homo sapiens) (aka g protein nucleolar 2)
C: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
D: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
E: gnb2 (homo sapiens) (aka g protein subunit beta 2)
F: None of the above. | A |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept corresponding to 'muscle form of glycogenin'. Answer using one of the provided options. | <Options>: A: glycogenin 1 (homo sapiens) (aka glycogenin 1)
B: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
C: glycogen synthase 1, muscle (mus musculus) (aka glycogen synthase 1, muscle)
D: glycogenin-1 (gallus gallus) (aka glycogenin 1)
E: glycogenin 1 (mus musculus) (aka glycogenin 1)
F: None of the above. | A |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept corresponding to 'glycogenin-1'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (homo sapiens) (aka glycogenin 2)
B: glycogenin 1 (homo sapiens) (aka glycogenin 1)
C: glycogenin 1 (xenopus tropicalis) (aka glycogenin 1)
D: glycogenin-1 (caenorhabditis elegans) (aka glycogenin-1)
E: glycogenin-1 (gallus gallus) (aka glycogenin 1)
F: None of the above. | B |
<Instruct>: Given the context 'hSK4, a member of a novel subfamily of calcium-activated potassium channels.
', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: huk4 (homo sapiens) (aka phospholipase d family member 3)
B: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
C: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
D: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
E: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
F: None of the above. | B |
<Instruct>: Given the context 'The gene for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
B: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
C: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
D: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
E: huk4 (homo sapiens) (aka phospholipase d family member 3)
F: None of the above. | C |
<Instruct>: Given the context 'In physiological saline hSK4 generates a conductance of approximately 12 pS, a value in close agreement with that of other cloned SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
B: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
C: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
D: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
E: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
F: None of the above. | E |
<Instruct>: Given the context 'Like other members of this family, the polypeptide encoded by hSK4 contains a previously unnoted leucine zipper-like domain in its C terminus of unknown function.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
B: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
C: huk4 (homo sapiens) (aka phospholipase d family member 3)
D: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
E: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
F: None of the above. | B |
<Instruct>: Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
B: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
C: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
D: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
E: huk4 (homo sapiens) (aka phospholipase d family member 3)
F: None of the above. | A |
<Instruct>: Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: stk4 (homo sapiens) (aka serine/threonine kinase 4)
B: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
C: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
D: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
E: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
F: None of the above. | F |
<Instruct>: Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
B: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
C: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
D: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
E: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
F: None of the above. | E |
<Instruct>: Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: stk4 (homo sapiens) (aka serine/threonine kinase 4)
B: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
C: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
D: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
E: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
F: None of the above. | B |
<Instruct>: Given the context 'Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.
', select the correct biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
B: il5rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
D: il5r (homo sapiens) (aka interleukin 5 receptor subunit alpha)
E: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
F: None of the above. | B |
<Instruct>: Given the context 'In some cases congenital PAP is associated with hereditary surfactant protein (SP)-B deficiency.', select the correct biomedical concept corresponding to 'surfactant protein (sp)-b'. Answer using one of the provided options. | <Options>: A: sp-b (sus scrofa) (aka surfactant protein b)
B: sp-b (homo sapiens) (aka surfactant protein b)
C: sftp1b (homo sapiens) (surfactant protein a1 (homo sapiens)) (aka surfactant protein a1)
D: surfactant protein c (homo sapiens) (aka surfactant protein c)
E: sftp1b (homo sapiens) (surfactant protein a2 (homo sapiens)) (aka surfactant protein a2)
F: None of the above. | B |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 3 receptor (homo sapiens) (aka colony stimulating factor 3 receptor)
B: colony stimulating factor 2 receptor subunit beta (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
D: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
E: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
F: None of the above. | B |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: betan (homo sapiens) (aka dna polymerase lambda)
B: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
C: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
D: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
E: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
F: None of the above. | F |
<Instruct>: Given the context 'Here, we describe an expression defect of beta c in three of seven pediatric patients with PAP and in one patient with severe lung disease suspected to be PAP.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
B: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
C: casein beta (homo sapiens) (aka casein beta)
D: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
E: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
F: None of the above. | F |
<Instruct>: Given the context 'The patients failed to express normal levels of beta c as shown by flow cytometry.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
B: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
C: betan (homo sapiens) (aka dna polymerase lambda)
D: betacellulin (homo sapiens) (aka betacellulin)
E: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
F: None of the above. | F |
<Instruct>: Given the context 'Strikingly reduced or absent function of beta c was demonstrated by ligand binding studies and progenitor clonogenic assays.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: betan (homo sapiens) (aka dna polymerase lambda)
B: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
C: betacellulin (homo sapiens) (aka betacellulin)
D: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
E: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
F: None of the above. | F |
<Instruct>: Given the context 'Analysis of beta c DNA revealed a point mutation from proline to threonine at codon 602 in one patient.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
B: betan (homo sapiens) (aka dna polymerase lambda)
C: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
D: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
E: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
F: None of the above. | F |
<Instruct>: Given the context 'Analysis of beta c DNA revealed a point mutation from proline to threonine at codon 602 in one patient.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
B: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
C: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
D: casein beta (homo sapiens) (aka casein beta)
E: betan (homo sapiens) (aka dna polymerase lambda)
F: None of the above. | F |
<Instruct>: Given the context 'Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.
', select the correct biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: quinolinate phosphoribosyltransferase (mus musculus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (oryctolagus cuniculus) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | D |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (gallus gallus) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (rattus norvegicus) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (bos taurus) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | B |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
B: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
C: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
E: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | C |
<Instruct>: Given the context 'As the first step to elucidate molecular basis underlying the quinolinate metabolism, the cDNA encoding human brain QPRTase was cloned and characterized.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
B: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
C: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
D: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | D |
<Instruct>: Given the context 'Utilizing partial amino acid sequences obtained from highly purified porcine kidney QPRTase, a human isolog was obtained from a human brain cDNA library.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
C: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
D: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | B |
<Instruct>: Given the context 'To confirm that the cDNA clone encodes human QPRTase, its functional expression was studied in a bacterial host.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
B: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
C: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
D: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
D: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
F: None of the above. | A |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'nadc'. Answer using one of the provided options. | <Options>: A: nadc (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: nadc-1 (oryctolagus cuniculus) (aka solute carrier family 13 member 2)
C: nuclear distribution c, dynein complex regulator (rattus norvegicus) (aka nuclear distribution c, dynein complex regulator)
D: nadc3 (rattus norvegicus) (aka solute carrier family 13 member 3)
E: nedscac (homo sapiens) (aka mediator complex subunit 27)
F: None of the above. | A |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
B: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
C: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
D: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
F: None of the above. | D |
<Instruct>: Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
B: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
E: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
C: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
D: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
E: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.
', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
D: tm4sf3 (homo sapiens) (aka tetraspanin 8)
E: tm4sf5 (sus scrofa) (aka transmembrane 4 l six family member 5)
F: None of the above. | B |
<Instruct>: Given the context 'In a previous large-scale screening for differentially expressed genes in pancreatic cancer, a gene was identified that was highly overexpressed in pancreatic cancer encoding a novel putative tetraspan transmembrane protein highly homologous to the tumour-associated antigen L6.', select the correct biomedical concept corresponding to 'tumour-associated antigen l6'. Answer using one of the provided options. | <Options>: A: cancer/testis antigen family 47 member a6 (homo sapiens) (aka cancer/testis antigen family 47 member a6)
B: ribosomal protein l6 (homo sapiens) (aka ribosomal protein l6)
C: rpl7ap6 (homo sapiens) (aka ribosomal protein l7a pseudogene 6)
D: l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens)) (aka transmembrane 4 l six family member 1)
E: mage family member a6 (homo sapiens) (aka mage family member a6)
F: None of the above. | D |
<Instruct>: Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf6 (homo sapiens) (aka tetraspanin 6)
B: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
C: tm4sf5 (sus scrofa) (aka transmembrane 4 l six family member 5)
D: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
E: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
F: None of the above. | E |
<Instruct>: Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', select the correct biomedical concept corresponding to 'transmembrane 4 superfamily member 5'. Answer using one of the provided options. | <Options>: A: tetraspanin 4 (homo sapiens) (aka tetraspanin 4)
B: transmembrane 4 l six family member 5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: transmembrane 4 superfamily member 4 (mus musculus) (aka transmembrane 4 superfamily member 4)
D: transmembrane 4 l six family member 4 (homo sapiens) (aka transmembrane 4 l six family member 4)
E: tetraspanin 5 (homo sapiens) (aka tetraspanin 5)
F: None of the above. | B |
<Instruct>: Given the context 'The cloned TM4SF5 cDNA has a 32bp 5'-untranslated region (UTR), a 591bp open reading frame (ORF) and a 85bp 3'UTR.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
D: tm4sf6 (homo sapiens) (aka tetraspanin 6)
E: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
F: None of the above. | B |
<Instruct>: Given the context 'The predicted TM4SF5 protein with 197 amino acids contains three NH2-terminal hydrophobic transmembrane regions, followed by an extracellular hydrophilic domain containing two potential N-linked glycosylation sites and a COOH-terminal hydrophobic transmembrane region.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
B: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
C: tm4sf3 (homo sapiens) (aka tetraspanin 8)
D: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
E: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
F: None of the above. | E |
<Instruct>: Given the context 'These structural features are shared by the L6 antigen and a number of related cell surface proteins associated with cell growth.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: adhesion g protein-coupled receptor g6 (homo sapiens) (aka adhesion g protein-coupled receptor g6)
B: h-l6 (homo sapiens) (aka transmembrane 4 l six family member 1)
C: l6 (homo sapiens) (ribosomal protein l6 (homo sapiens)) (aka ribosomal protein l6)
D: lethal (1) l6 (drosophila melanogaster) (aka lethal (1) l6)
E: ribosomal protein l6 pseudogene 6 (homo sapiens) (aka ribosomal protein l6 pseudogene 6)
F: None of the above. | B |
<Instruct>: Given the context 'TM4SF5 was overexpressed in pancreatic cancer tissues as compared to both normal pancreas and chronic pancreatitis tissues, and was detected at high levels in other tumour tissues.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
B: tm4sf6 (homo sapiens) (aka tetraspanin 6)
C: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
D: tm4sf8 (homo sapiens) (aka tetraspanin 3)
E: tm4sf3 (homo sapiens) (aka tetraspanin 8)
F: None of the above. | A |
<Instruct>: Given the context 'Although the precise function of TM4SF5 remains to be elucidated it may be useful in a clinical setting for tumour diagnosis and/or therapy.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
B: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
C: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
D: tm4sf (homo sapiens) (aka tetraspanin 1)
E: tm4sf3 (homo sapiens) (aka tetraspanin 8)
F: None of the above. | A |
<Instruct>: Given the context 'This hypothesis is supported by the strong homology to the L6 antigen, which has proved promising in immunological, therapeutic and diagnostic approaches.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: h-l6 (homo sapiens) (aka transmembrane 4 l six family member 1)
B: adhesion g protein-coupled receptor g6 (homo sapiens) (aka adhesion g protein-coupled receptor g6)
C: l6 (mus musculus) (transmembrane 4 superfamily member 1 (mus musculus)) (aka transmembrane 4 superfamily member 1)
D: l7rn6 (homo sapiens) (aka heat shock protein nuclear import factor hikeshi)
E: ribosomal protein l6 pseudogene 6 (homo sapiens) (aka ribosomal protein l6 pseudogene 6)
F: None of the above. | A |
<Instruct>: Given the context 'This hypothesis is supported by the strong homology to the L6 antigen, which has proved promising in immunological, therapeutic and diagnostic approaches.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: l6 (mus musculus) (transmembrane 4 superfamily member 1 (mus musculus)) (aka transmembrane 4 superfamily member 1)
B: l7rn6 (homo sapiens) (aka heat shock protein nuclear import factor hikeshi)
C: l6 (drosophila melanogaster) (lethal (1) l6 (drosophila melanogaster)) (aka lethal (1) l6)
D: adhesion g protein-coupled receptor g6 (homo sapiens) (aka adhesion g protein-coupled receptor g6)
E: ribosomal protein l6 (homo sapiens) (aka ribosomal protein l6)
F: None of the above. | F |
<Instruct>: Given the context 'Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4).
', select the correct biomedical concept corresponding to 'ribosomal protein l14'. Answer using one of the provided options. | <Options>: A: ribosomal protein l14 (mus musculus) (aka ribosomal protein l14)
B: 50s ribosomal protein l14 (glycine max) (aka 50s ribosomal protein l14)
C: 60s ribosomal protein l14-like (homo sapiens) (aka 60s ribosomal protein l14-like)
D: rpl14 (homo sapiens) (aka ribosomal protein l14)
E: mitochondrial ribosomal protein l14 (homo sapiens) (aka mitochondrial ribosomal protein l14)
F: None of the above. | D |
<Instruct>: Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', select the correct biomedical concept corresponding to 'ribosomal subunit protein l14'. Answer using one of the provided options. | <Options>: A: ribosomal protein l14 (homo sapiens) (aka ribosomal protein l14)
B: 60s ribosomal protein l14-like (homo sapiens) (aka 60s ribosomal protein l14-like)
C: l14 (drosophila melanogaster) (ribosomal protein l14 (drosophila melanogaster)) (aka ribosomal protein l14)
D: mrp-l14 (homo sapiens) (mitochondrial ribosomal protein l14 (homo sapiens)) (aka mitochondrial ribosomal protein l14)
E: ribosomal protein l14 (mus musculus) (aka ribosomal protein l14)
F: None of the above. | A |
<Instruct>: Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', select the correct biomedical concept corresponding to 'hrl14'. Answer using one of the provided options. | <Options>: A: rl14 (homo sapiens) (aka ribosomal protein l14)
B: arl14 (homo sapiens) (aka arf like gtpase 14)
C: ribosomal protein l24-like (drosophila melanogaster) (aka ribosomal protein l24-like)
D: bcl2l14 (homo sapiens) (aka bcl2 like 14)
E: rpl14l (homo sapiens) (aka ribosomal protein l14 pseudogene 1)
F: None of the above. | A |
<Instruct>: Given the context 'A significant identity for hRL14 was observed with rat RL14 (85% identity), with exception of COOH-terminal region, but not with any eukaryote amino acid sequences so far deposited to database.', select the correct biomedical concept corresponding to 'hrl14'. Answer using one of the provided options. | <Options>: A: hmettl14 (homo sapiens) (aka methyltransferase 14, n6-adenosine-methyltransferase non-catalytic subunit)
B: hmgb1l14 (homo sapiens) (aka high mobility group box 1 pseudogene 14)
C: ribosomal protein l24-like (drosophila melanogaster) (aka ribosomal protein l24-like)
D: hrl14 (homo sapiens) (aka ribosomal protein l14)
E: rpl14l (homo sapiens) (aka ribosomal protein l14 pseudogene 1)
F: None of the above. | D |
<Instruct>: Given the context 'A significant identity for hRL14 was observed with rat RL14 (85% identity), with exception of COOH-terminal region, but not with any eukaryote amino acid sequences so far deposited to database.', select the correct biomedical concept corresponding to 'rl14'. Answer using one of the provided options. | <Options>: A: rab14, member ras oncogene family l homeolog (xenopus laevis) (aka rab14, member ras oncogene family l homeolog)
B: protein lurp-one-related 14 (glycine max) (aka protein lurp-one-related 14)
C: rl14 (homo sapiens) (aka ribosomal protein l14)
D: cluster homolog of immunoglobin like receptor like 14 (gallus gallus) (aka cluster homolog of immunoglobin like receptor like 14)
E: ribosomal rna-processing protein 14-c-like (glycine max) (aka ribosomal rna-processing protein 14-c-like)
F: None of the above. | F |
<Instruct>: Given the context 'The typical features of ribosomal proteins were observed in hRL14, as seen in nuclear targeting sequences necessary for the transport from cytoplasm to nucleolus, a bZIP like (basic region-leucine zipper) element for the binding to rRNA, and the internal repeat sequences; the pentapeptide QKA(A/S)X.', select the correct biomedical concept corresponding to 'hrl14'. Answer using one of the provided options. | <Options>: A: bcl2l14 (homo sapiens) (aka bcl2 like 14)
B: rpl14l (homo sapiens) (aka ribosomal protein l14 pseudogene 1)
C: rpl14 (homo sapiens) (aka ribosomal protein l14)
D: hmettl14 (homo sapiens) (aka methyltransferase 14, n6-adenosine-methyltransferase non-catalytic subunit)
E: arl14 (homo sapiens) (aka arf like gtpase 14)
F: None of the above. | C |
<Instruct>: Given the context 'The COOH-terminal region of the transcripts contained fifteen triplet repeats (GCT; alanine) at nucleotide 465 to 509, which is significantly expanded compared to the rat RL14.', select the correct biomedical concept corresponding to 'rl14'. Answer using one of the provided options. | <Options>: A: rpl14 (candida albicans sc5314) (aka ribosomal 60s subunit protein l14b)
B: rpl14 (drosophila melanogaster) (aka ribosomal protein l14)
C: rpl14l (homo sapiens) (aka ribosomal protein l14 pseudogene 1)
D: cluster homolog of immunoglobin like receptor like 14 (gallus gallus) (aka cluster homolog of immunoglobin like receptor like 14)
E: rl14 (homo sapiens) (aka ribosomal protein l14)
F: None of the above. | F |
<Instruct>: Given the context 'Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
D-Dopachrome tautomerase converts 2-carboxy-2,3-dihydroindole-5,6-quinone (D-dopachrome) into 5,6-dihydroxyindole.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: dopachrome tautomerase (mus musculus) (aka dopachrome tautomerase)
B: d-dopachrome tautomerase (bos taurus) (aka d-dopachrome tautomerase)
C: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
D: dopachrome tautomerase (xenopus tropicalis) (aka dopachrome tautomerase)
E: d-dopachrome tautomerase (mus musculus) (aka d-dopachrome tautomerase)
F: None of the above. | C |
<Instruct>: Given the context 'Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
D-Dopachrome tautomerase converts 2-carboxy-2,3-dihydroindole-5,6-quinone (D-dopachrome) into 5,6-dihydroxyindole.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
B: d-dopachrome tautomerase-like (homo sapiens) (aka d-dopachrome tautomerase-like)
C: dopachrome tautomerase (homo sapiens) (aka dopachrome tautomerase)
D: d-dopachrome tautomerase like (homo sapiens) (aka d-dopachrome tautomerase like)
E: dopachrome tautomerase (xenopus tropicalis) (aka dopachrome tautomerase)
F: None of the above. | A |
<Instruct>: Given the context 'This protein has an amino acid sequence that is highly homologous with that of macrophage migration inhibitory factor (MIF), which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation.', select the correct biomedical concept corresponding to 'macrophage migration inhibitory factor'. Answer using one of the provided options. | <Options>: A: mif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens)) (aka macrophage migration inhibitory factor)
B: migration and invasion inhibitory protein (mus musculus) (aka migration and invasion inhibitory protein)
C: macrophage migration inhibitory factor (glycosylation-inhibiting factor) (mus musculus) (aka macrophage migration inhibitory factor (glycosylation-inhibiting factor))
D: macrophage migration inhibitory factor (xenopus tropicalis) (aka macrophage migration inhibitory factor)
E: macrophage migration inhibitory factor (bos taurus) (aka macrophage migration inhibitory factor)
F: None of the above. | A |
<Instruct>: Given the context 'This protein has an amino acid sequence that is highly homologous with that of macrophage migration inhibitory factor (MIF), which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation.', select the correct biomedical concept corresponding to 'macrophage migration inhibitory factor'. Answer using one of the provided options. | <Options>: A: macrophage migration inhibitory factor (caenorhabditis elegans) (aka macrophage migration inhibitory factor)
B: macrophage migration inhibitory factor (bos taurus) (aka macrophage migration inhibitory factor)
C: migration and invasion inhibitory protein (mus musculus) (aka migration and invasion inhibitory protein)
D: migration and invasion inhibitory protein (homo sapiens) (aka migration and invasion inhibitory protein)
E: macrophage migration inhibitory factor (glycosylation-inhibiting factor) (mus musculus) (aka macrophage migration inhibitory factor (glycosylation-inhibiting factor))
F: None of the above. | F |
<Instruct>: Given the context 'This protein has an amino acid sequence that is highly homologous with that of macrophage migration inhibitory factor (MIF), which has the potential to catalyze D-dopachrome to 5,6-dihydroxyindole-2-carboxylic acid and is an important cytokine for T-lymphocyte activation.', select the correct biomedical concept corresponding to 'mif'. Answer using one of the provided options. | <Options>: A: macrophage migration inhibitory factor (xenopus tropicalis) (aka macrophage migration inhibitory factor)
B: macrophage migration inhibitory factor (glycosylation-inhibiting factor) (mus musculus) (aka macrophage migration inhibitory factor (glycosylation-inhibiting factor))
C: mif (homo sapiens) (macrophage migration inhibitory factor (homo sapiens)) (aka macrophage migration inhibitory factor)
D: migration and invasion inhibitory protein (homo sapiens) (aka migration and invasion inhibitory protein)
E: mif1 (homo sapiens) (aka homocysteine inducible er protein with ubiquitin like domain 1)
F: None of the above. | C |
<Instruct>: Given the context 'We isolated and sequenced a 566 bp-long cDNA encoding human D-dopachrome tautomerase.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: d-dopachrome tautomerase like (homo sapiens) (aka d-dopachrome tautomerase like)
B: d-dopachrome tautomerase (mus musculus) (aka d-dopachrome tautomerase)
C: dopachrome tautomerase (mus musculus) (aka dopachrome tautomerase)
D: dopachrome tautomerase (xenopus tropicalis) (aka dopachrome tautomerase)
E: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
F: None of the above. | E |
<Instruct>: Given the context 'Northern blot analysis demonstrated that mRNA of D-dopachrome tautomerase is expressed in a large amount in the liver, and to lesser extent in other organs, including the heart, lung and pancreas.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: d-dopachrome tautomerase (mus musculus) (aka d-dopachrome tautomerase)
B: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
C: d-dopachrome tautomerase (xenopus tropicalis) (aka d-dopachrome tautomerase)
D: d-dopachrome tautomerase like (homo sapiens) (aka d-dopachrome tautomerase like)
E: dopachrome tautomerase (homo sapiens) (aka dopachrome tautomerase)
F: None of the above. | B |
<Instruct>: Given the context 'After purification of D-dopachrome tautomerase expressed in E. coli, we confirmed that the recombinant protein catalyzes the conversion of D-dopachrome to 5,6-dihydroxyindole.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: dopachrome tautomerase (xenopus tropicalis) (aka dopachrome tautomerase)
B: dopachrome tautomerase (homo sapiens) (aka dopachrome tautomerase)
C: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
D: dopachrome tautomerase (bos taurus) (aka dopachrome tautomerase)
E: d-dopachrome tautomerase (bos taurus) (aka d-dopachrome tautomerase)
F: None of the above. | C |
<Instruct>: Given the context 'Although the precise pathophysiological function of D-dopachrome tautomerase remains to be elucidated, the present results could contribute to further understanding of isomerase activity in relation to the immune response.', select the correct biomedical concept corresponding to 'd-dopachrome tautomerase'. Answer using one of the provided options. | <Options>: A: dopachrome tautomerase (xenopus tropicalis) (aka dopachrome tautomerase)
B: d-dopachrome tautomerase (homo sapiens) (aka d-dopachrome tautomerase)
C: d-dopachrome tautomerase (mus musculus) (aka d-dopachrome tautomerase)
D: d-dopachrome tautomerase like (homo sapiens) (aka d-dopachrome tautomerase like)
E: dopachrome tautomerase (homo sapiens) (aka dopachrome tautomerase)
F: None of the above. | B |
<Instruct>: Given the context 'Isolation of full-length cDNA of mouse PAX4 gene and identification of its human homologue.
', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (bos taurus) (aka paired box 4)
B: paired box 4 (gallus gallus) (aka paired box 4)
C: paired box 4 (homo sapiens) (aka paired box 4)
D: pax-4 (xenopus tropicalis) (aka paired box 4)
E: pax-4 (mus musculus) (aka paired box 4)
F: None of the above. | E |
<Instruct>: Given the context 'Recent genetic studies have suggested that PAX4, a member of the paired box (PAX) gene family, is involved in the mechanism regulating the fate of pancreatic islet endocrine progenitor cells.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
B: paired box 4 (bos taurus) (aka paired box 4)
C: pax4 (mus musculus) (aka paired box 4)
D: pax4 (xenopus tropicalis) (aka paired box 4)
E: paired box 4 (gallus gallus) (aka paired box 4)
F: None of the above. | C |
<Instruct>: Given the context 'Murine PAX4 was originally identified by genomic screening and, to date, only a partial sequence of PAX4 has been reported.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax-4 (mus musculus) (aka paired box 4)
B: pax-4 (xenopus tropicalis) (aka paired box 4)
C: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
D: paired box 4 (gallus gallus) (aka paired box 4)
E: pax4 (homo sapiens) (aka paired box 4)
F: None of the above. | A |
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