instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'Murine PAX4 was originally identified by genomic screening and, to date, only a partial sequence of PAX4 has been reported.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax4 (homo sapiens) (aka paired box 4)
B: pax4 (mus musculus) (aka paired box 4)
C: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
D: paired box 4 (bos taurus) (aka paired box 4)
E: pax4 (xenopus tropicalis) (aka paired box 4)
F: None of the above. | B |
<Instruct>: Given the context 'In this study, we cloned the full-length cDNA of mouse PAX4 by RACE (rapid amplification of cDNA ends) using RNA from MIN6 cells, a mouse insulinoma cell line.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (xenopus tropicalis) (aka paired box 4)
B: paired box 4 (homo sapiens) (aka paired box 4)
C: paired box 4 (gallus gallus) (aka paired box 4)
D: pax4 (mus musculus) (aka paired box 4)
E: paired box 4 (bos taurus) (aka paired box 4)
F: None of the above. | D |
<Instruct>: Given the context 'In this study, we cloned the full-length cDNA of mouse PAX4 by RACE (rapid amplification of cDNA ends) using RNA from MIN6 cells, a mouse insulinoma cell line.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (bos taurus) (aka paired box 4)
B: pax4 (homo sapiens) (aka paired box 4)
C: pax-4 (xenopus tropicalis) (aka paired box 4)
D: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
E: paired box 4 (gallus gallus) (aka paired box 4)
F: None of the above. | F |
<Instruct>: Given the context 'The deduced mouse PAX4 protein was 349 amino acids and had the predicted molecular weight of 38 kDa.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (gallus gallus) (aka paired box 4)
B: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
C: pax4 (homo sapiens) (aka paired box 4)
D: paired box 4 (bos taurus) (aka paired box 4)
E: pax-4 (mus musculus) (aka paired box 4)
F: None of the above. | E |
<Instruct>: Given the context 'Two DNA binding motifs, a 128-amino acid paired domain and a 61-amino acid paired-type homeodomain exhibit the highest amino acid homology with PAX6 (71.2%, 65.0%, respectively), another member of the PAX gene family.', select the correct biomedical concept corresponding to 'pax6'. Answer using one of the provided options. | <Options>: A: pax6 (xenopus laevis) (paired box 6 l homeolog (xenopus laevis)) (aka paired box 6 l homeolog)
B: paired box 6 like (xenopus tropicalis) (aka paired box 6 like)
C: paired box 6 (homo sapiens) (aka paired box 6)
D: pax6.2 (xenopus laevis) (paired box 6 like s homeolog (xenopus laevis)) (aka paired box 6 like s homeolog)
E: pax6 (xenopus laevis) (paired box 6 s homeolog (xenopus laevis)) (aka paired box 6 s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'However, the sequence of the C-terminal segment of PAX4 diverged and showed no significant homology with any other known PAX genes.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (gallus gallus) (aka paired box 4)
B: paired box 4 (bos taurus) (aka paired box 4)
C: pax4 (xenopus tropicalis) (aka paired box 4)
D: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
E: pax4 (mus musculus) (aka paired box 4)
F: None of the above. | E |
<Instruct>: Given the context 'As to the genomic DNA, the coding region of the mouse PAX4 gene spanned approximately 5.5 kb and was composed of 10 exons.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax4 (mus musculus) (aka paired box 4)
B: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
C: paired box 4 (xenopus tropicalis) (aka paired box 4)
D: paired box 4 (homo sapiens) (aka paired box 4)
E: paired box 4 (bos taurus) (aka paired box 4)
F: None of the above. | A |
<Instruct>: Given the context 'In the public DNA database, a human cosmid (g1572c264), which was localized on human chromosome 7q31.3, was found to contain a gene homologous to PAX4.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
B: pax4 (xenopus tropicalis) (aka paired box 4)
C: pax4 (homo sapiens) (aka paired box 4)
D: pax-4 (mus musculus) (aka paired box 4)
E: paired box 4 (bos taurus) (aka paired box 4)
F: None of the above. | C |
<Instruct>: Given the context 'The nucleotide and protein sequence homologies between mouse PAX4 and its human homologue were 83.1% and 80.0%, respectively.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box 4 (xenopus tropicalis) (aka paired box 4)
B: paired box 4 (homo sapiens) (aka paired box 4)
C: paired box 4 (gallus gallus) (aka paired box 4)
D: pax-4 (mus musculus) (aka paired box 4)
E: paired box 4 (bos taurus) (aka paired box 4)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', select the correct biomedical concept corresponding to 'arp5'. Answer using one of the provided options. | <Options>: A: actin-related protein 2/3 complex, subunit 5 (drosophila melanogaster) (aka actin-related protein 2/3 complex, subunit 5)
B: arp5 actin related protein 5 homolog (xenopus tropicalis) (aka arp5 actin related protein 5 homolog)
C: arl5ap5 (homo sapiens) (aka arl5a pseudogene 5)
D: actin related protein 5 (homo sapiens) (aka actin related protein 5)
E: arp5 actin related protein 5 homolog s homeolog (xenopus laevis) (aka arp5 actin related protein 5 homolog s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', select the correct biomedical concept corresponding to 'adp-ribosylation factor 5'. Answer using one of the provided options. | <Options>: A: adp ribosylation factor 5 (sus scrofa) (aka adp ribosylation factor 5)
B: adp-ribosylation factor 5 (gallus gallus) (aka adp-ribosylation factor 5)
C: adp-ribosylation factor-like protein 5 (caenorhabditis elegans) (aka adp-ribosylation factor-like protein 5)
D: arf5 (homo sapiens) (aka arf gtpase 5)
E: adp-ribosylation factor-like 5 (drosophila melanogaster) (aka adp-ribosylation factor-like 5)
F: None of the above. | D |
<Instruct>: Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', select the correct biomedical concept corresponding to 'arp5'. Answer using one of the provided options. | <Options>: A: arp5 actin-related protein 5 homolog (gallus gallus) (aka arp5 actin-related protein 5 homolog)
B: arp5 actin related protein 5 homolog (xenopus tropicalis) (aka arp5 actin related protein 5 homolog)
C: arp5 (homo sapiens) (actin related protein 5 (homo sapiens)) (aka actin related protein 5)
D: arl5ap5 (homo sapiens) (aka arl5a pseudogene 5)
E: actin-related protein arp5 (saccharomyces cerevisiae s288c) (aka actin-related protein arp5)
F: None of the above. | F |
<Instruct>: Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax4 (mus musculus) (aka paired box 4)
B: paired box 4 (xenopus tropicalis) (aka paired box 4)
C: paired box 4 (homo sapiens) (aka paired box 4)
D: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
E: paired box 4 (bos taurus) (aka paired box 4)
F: None of the above. | C |
<Instruct>: Given the context 'Interestingly, the ARP5 (ADP-ribosylation factor 5) gene was also found in the same cosmid g1572c264, suggesting the ARP5 gene to be adjacent to the human PAX4 homologue.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax-4 (mus musculus) (aka paired box 4)
B: paired box 4 (gallus gallus) (aka paired box 4)
C: paired box 4 (xenopus tropicalis) (aka paired box 4)
D: paired box 4 (bos taurus) (aka paired box 4)
E: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
F: None of the above. | F |
<Instruct>: Given the context 'The results of this study, i.e. isolation of the full-length cDNA sequence of PAX4 and identification of the homologous human gene, will facilitate further functional and genetic studies of the PAX4 gene.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
B: paired box 4 (gallus gallus) (aka paired box 4)
C: paired box 4 (homo sapiens) (aka paired box 4)
D: pax-4 (xenopus tropicalis) (aka paired box 4)
E: pax4 (mus musculus) (aka paired box 4)
F: None of the above. | E |
<Instruct>: Given the context 'The results of this study, i.e. isolation of the full-length cDNA sequence of PAX4 and identification of the homologous human gene, will facilitate further functional and genetic studies of the PAX4 gene.', select the correct biomedical concept corresponding to 'pax4'. Answer using one of the provided options. | <Options>: A: pax4 (homo sapiens) (aka paired box 4)
B: paired box 4 (gallus gallus) (aka paired box 4)
C: paired box protein pax-4 (xenopus laevis) (aka paired box protein pax-4)
D: pax-4 (mus musculus) (aka paired box 4)
E: paired box 4 (xenopus tropicalis) (aka paired box 4)
F: None of the above. | A |
<Instruct>: Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', select the correct biomedical concept corresponding to 'gsta3'. Answer using one of the provided options. | <Options>: A: gsta3 (gallus gallus) (aka glutathione s-transferase alpha 3)
B: gstm3 (homo sapiens) (aka glutathione s-transferase mu 3)
C: glutathione s-transferase alpha 3 (homo sapiens) (aka glutathione s-transferase alpha 3)
D: gstap3 (homo sapiens) (aka glutathione s-transferase alpha 11, pseudogene)
E: gstm3p (homo sapiens) (aka glutathione s-transferase mu 3 pseudogene 1)
F: None of the above. | C |
<Instruct>: Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', select the correct biomedical concept corresponding to 'gsta4'. Answer using one of the provided options. | <Options>: A: gsta4 (sus scrofa) (aka glutathione s-transferase alpha 4)
B: gstt4 (homo sapiens) (aka glutathione s-transferase theta 4)
C: gstap4 (homo sapiens) (aka glutathione s-transferase alpha 9, pseudogene)
D: gst4 (homo sapiens) (aka glutathione s-transferase mu 2)
E: gsta4 (homo sapiens) (aka glutathione s-transferase alpha 4)
F: None of the above. | E |
<Instruct>: Given the context 'Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.
', select the correct biomedical concept corresponding to 'gsta4-4'. Answer using one of the provided options. | <Options>: A: gsta4 (homo sapiens) (aka glutathione s-transferase alpha 4)
B: gstm4 (homo sapiens) (aka glutathione s-transferase mu 4)
C: gst4 (homo sapiens) (aka glutathione s-transferase mu 2)
D: gsta4-ps4 (rattus norvegicus) (aka glutathione s-transferase alpha 4, pseudogene 4)
E: gsta4-4 (xenopus tropicalis) (aka glutathione s-transferase alpha 4)
F: None of the above. | A |
<Instruct>: Given the context 'An incomplete transcript of the previously described GSTA3 gene was identified in a cDNA library derived from 8-9 week placenta.', select the correct biomedical concept corresponding to 'gsta3'. Answer using one of the provided options. | <Options>: A: gstap3 (homo sapiens) (aka glutathione s-transferase alpha 11, pseudogene)
B: gstm3 (homo sapiens) (aka glutathione s-transferase mu 3)
C: gsta3l (gallus gallus) (aka glutathione s-transferase alpha 4)
D: gst-iii (homo sapiens) (aka microsomal glutathione s-transferase 3)
E: gsta3-3 (homo sapiens) (aka glutathione s-transferase alpha 3)
F: None of the above. | E |
<Instruct>: Given the context 'This indicates that the GSTA3 gene is functional and is possibly under specific developmental regulation.', select the correct biomedical concept corresponding to 'gsta3'. Answer using one of the provided options. | <Options>: A: gsta3l (gallus gallus) (aka glutathione s-transferase alpha 4)
B: gsta3 (gallus gallus) (aka glutathione s-transferase alpha 3)
C: gstap3 (homo sapiens) (aka glutathione s-transferase alpha 11, pseudogene)
D: gstm3 (homo sapiens) (aka glutathione s-transferase mu 3)
E: glutathione s-transferase alpha 3 (homo sapiens) (aka glutathione s-transferase alpha 3)
F: None of the above. | E |
<Instruct>: Given the context 'A second cDNA, termed GSTA4, was identified in a brain cDNA library.', select the correct biomedical concept corresponding to 'gsta4'. Answer using one of the provided options. | <Options>: A: gst4 (homo sapiens) (aka glutathione s-transferase mu 2)
B: gsta4 (sus scrofa) (aka glutathione s-transferase alpha 4)
C: gstt4 (homo sapiens) (aka glutathione s-transferase theta 4)
D: gsta4-4 (homo sapiens) (aka glutathione s-transferase alpha 4)
E: gstap4 (homo sapiens) (aka glutathione s-transferase alpha 9, pseudogene)
F: None of the above. | D |
<Instruct>: Given the context 'The encoded GSTA4-4 enzyme was expressed in Escherichia coli and was found to be immunologically distinct from GSTA1-1 and to have high activity with alk-2-enals.', select the correct biomedical concept corresponding to 'gsta4-4'. Answer using one of the provided options. | <Options>: A: gsta4-ps4 (rattus norvegicus) (aka glutathione s-transferase alpha 4, pseudogene 4)
B: gsta4p (homo sapiens) (aka glutathione s-transferase alpha 9, pseudogene)
C: gstm4 (homo sapiens) (aka glutathione s-transferase mu 4)
D: gsta4 (homo sapiens) (aka glutathione s-transferase alpha 4)
E: gsta4-4 (xenopus tropicalis) (aka glutathione s-transferase alpha 4)
F: None of the above. | D |
<Instruct>: Given the context 'The encoded GSTA4-4 enzyme was expressed in Escherichia coli and was found to be immunologically distinct from GSTA1-1 and to have high activity with alk-2-enals.', select the correct biomedical concept corresponding to 'gsta1-1'. Answer using one of the provided options. | <Options>: A: gsta11p (homo sapiens) (aka glutathione s-transferase alpha 11, pseudogene)
B: gst-1 (homo sapiens) (aka carbohydrate sulfotransferase 1)
C: gsta1 (homo sapiens) (aka glutathione s-transferase alpha 1)
D: gstap1 (homo sapiens) (aka glutathione s-transferase alpha 6, pseudogene)
E: gsts1-1 (homo sapiens) (aka hematopoietic prostaglandin d synthase)
F: None of the above. | C |
<Instruct>: Given the context 'The encoded GSTA4-4 enzyme was expressed in Escherichia coli and was found to be immunologically distinct from GSTA1-1 and to have high activity with alk-2-enals.', select the correct biomedical concept corresponding to 'gsta1-1'. Answer using one of the provided options. | <Options>: A: gsta1-1 (xenopus laevis) (glutathione s-transferase alpha 1 s homeolog (xenopus laevis)) (aka glutathione s-transferase alpha 1 s homeolog)
B: gst-1 (homo sapiens) (aka carbohydrate sulfotransferase 1)
C: gstap1 (homo sapiens) (aka glutathione s-transferase alpha 6, pseudogene)
D: gstm1a-1a (homo sapiens) (aka glutathione s-transferase mu 1)
E: gsta11p (homo sapiens) (aka glutathione s-transferase alpha 11, pseudogene)
F: None of the above. | F |
<Instruct>: Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', select the correct biomedical concept corresponding to 'gsta4-4'. Answer using one of the provided options. | <Options>: A: gsta4-4 (homo sapiens) (aka glutathione s-transferase alpha 4)
B: gstm4-4 (homo sapiens) (aka glutathione s-transferase mu 4)
C: gsta4-4 (xenopus laevis) (aka glutathione s-transferase alpha 4 s homeolog)
D: gstt4 (homo sapiens) (aka glutathione s-transferase theta 4)
E: gst4 (homo sapiens) (aka glutathione s-transferase mu 2)
F: None of the above. | A |
<Instruct>: Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', select the correct biomedical concept corresponding to 'gst5.7'. Answer using one of the provided options. | <Options>: A: gstap5 (homo sapiens) (aka glutathione s-transferase alpha 12, pseudogene)
B: gst-5 (homo sapiens) (aka carbohydrate sulfotransferase 7)
C: gstl5 (glycine max) (aka glutathione s-transferase l3)
D: gst5 (homo sapiens) (aka glutathione s-transferase mu 3)
E: gst5.7 (mus musculus) (aka glutathione s-transferase, alpha 4)
F: None of the above. | E |
<Instruct>: Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', select the correct biomedical concept corresponding to 'gst8-8 alpha'. Answer using one of the provided options. | <Options>: A: gstt4 (homo sapiens) (aka glutathione s-transferase theta 4)
B: gstu8 (glycine max) (aka glutathione s-transferase u17-like)
C: gsta4 (homo sapiens) (aka glutathione s-transferase alpha 4)
D: gsta4p (homo sapiens) (aka glutathione s-transferase alpha 9, pseudogene)
E: glutathione s-transferase gst 8 (glycine max) (aka glutathione s-transferase gst 8)
F: None of the above. | F |
<Instruct>: Given the context 'Although GSTA4-4 appears to be functionally similar to the mouse GST5.7 and rat GST8-8 Alpha class enzymes, sequence comparisons and phylogenetic analysis suggest that GSTA4-4 may be a member of a distinct Alpha class subgroup.', select the correct biomedical concept corresponding to 'gsta4-4'. Answer using one of the provided options. | <Options>: A: gst4 (homo sapiens) (aka glutathione s-transferase mu 2)
B: gsta4-4 (xenopus laevis) (aka glutathione s-transferase alpha 4 s homeolog)
C: gsta4-4 (xenopus tropicalis) (aka glutathione s-transferase alpha 4)
D: gstm4 (homo sapiens) (aka glutathione s-transferase mu 4)
E: gsta4 (homo sapiens) (aka glutathione s-transferase alpha 4)
F: None of the above. | E |
<Instruct>: Given the context 'Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion.
', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actinin alpha 4 (bos taurus) (aka actinin alpha 4)
B: actn4.l (xenopus laevis) (actinin alpha 4 s homeolog (xenopus laevis)) (aka actinin alpha 4 s homeolog)
C: actinin-4 (homo sapiens) (aka actinin alpha 4)
D: actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis)) (aka actinin alpha 4 l homeolog)
E: actinin alpha 4 (mus musculus) (aka actinin alpha 4)
F: None of the above. | C |
<Instruct>: Given the context 'This isoform (designated actinin-4) was concentrated in the cytoplasm where cells were sharply extended and in cells migrating and located at the edge of cell clusters, but was absent from focal adhesion plaques or adherens junctions, where the classic isoform (actinin-1) was concentrated.', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actn4 (mus musculus) (aka actinin alpha 4)
B: actinin alpha 4 (bos taurus) (aka actinin alpha 4)
C: actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis)) (aka actinin alpha 4 l homeolog)
D: actinin alpha 4 (homo sapiens) (aka actinin alpha 4)
E: actinin alpha 4 (xenopus tropicalis) (aka actinin alpha 4)
F: None of the above. | D |
<Instruct>: Given the context 'This isoform (designated actinin-4) was concentrated in the cytoplasm where cells were sharply extended and in cells migrating and located at the edge of cell clusters, but was absent from focal adhesion plaques or adherens junctions, where the classic isoform (actinin-1) was concentrated.', select the correct biomedical concept corresponding to 'actinin-1'. Answer using one of the provided options. | <Options>: A: actinin alpha 3 (homo sapiens) (aka actinin alpha 3)
B: actn1 (homo sapiens) (aka actinin alpha 1)
C: actinin alpha 4 (homo sapiens) (aka actinin alpha 4)
D: actinin (xenopus laevis) (actinin alpha 1 s homeolog (xenopus laevis)) (aka actinin alpha 1 s homeolog)
E: actinin (xenopus laevis) (actinin alpha 1 l homeolog (xenopus laevis)) (aka actinin alpha 1 l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'Actinin-4 shifted steadily from the cytoplasm to the nucleus upon inhibition of phosphatidylinositol 3 kinase or actin depolymerization.', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actinin alpha 4 (homo sapiens) (aka actinin alpha 4)
B: actn4.l (xenopus laevis) (actinin alpha 4 s homeolog (xenopus laevis)) (aka actinin alpha 4 s homeolog)
C: actinin alpha 4 (xenopus tropicalis) (aka actinin alpha 4)
D: actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis)) (aka actinin alpha 4 l homeolog)
E: actin;actin-4 (caenorhabditis elegans) (aka actin;actin-4)
F: None of the above. | A |
<Instruct>: Given the context 'The cytoplasmic localization of actinin-4 was closely associated with an infiltrative histological phenotype and correlated significantly with a poorer prognosis in 61 cases of breast cancer.', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actinin-4 (homo sapiens) (aka actinin alpha 4)
B: actinin alpha 4 (bos taurus) (aka actinin alpha 4)
C: actn4.l (xenopus laevis) (actinin alpha 4 s homeolog (xenopus laevis)) (aka actinin alpha 4 s homeolog)
D: actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis)) (aka actinin alpha 4 l homeolog)
E: actinin alpha 4 (mus musculus) (aka actinin alpha 4)
F: None of the above. | A |
<Instruct>: Given the context 'These findings suggest that cytoplasmic actinin-4 regulates the actin cytoskeleton and increases cellular motility and that its inactivation by transfer to the nucleus abolishes the metastatic potential of human cancers.', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actn4 (mus musculus) (aka actinin alpha 4)
B: actin;actin-4 (caenorhabditis elegans) (aka actin;actin-4)
C: actn4.l (xenopus laevis) (actinin alpha 4 l homeolog (xenopus laevis)) (aka actinin alpha 4 l homeolog)
D: actn4.l (xenopus laevis) (actinin alpha 4 s homeolog (xenopus laevis)) (aka actinin alpha 4 s homeolog)
E: actn4 (homo sapiens) (aka actinin alpha 4)
F: None of the above. | E |
<Instruct>: Given the context 'These findings suggest that cytoplasmic actinin-4 regulates the actin cytoskeleton and increases cellular motility and that its inactivation by transfer to the nucleus abolishes the metastatic potential of human cancers.', select the correct biomedical concept corresponding to 'actinin-4'. Answer using one of the provided options. | <Options>: A: actinin alpha 4 (xenopus tropicalis) (aka actinin alpha 4)
B: actinin alpha 4 (mus musculus) (aka actinin alpha 4)
C: actn4.l (xenopus laevis) (actinin alpha 4 s homeolog (xenopus laevis)) (aka actinin alpha 4 s homeolog)
D: actin;actin-4 (caenorhabditis elegans) (aka actin;actin-4)
E: actinin alpha 4 (bos taurus) (aka actinin alpha 4)
F: None of the above. | F |
<Instruct>: Given the context 'Considering the well established role of nonclassical HLA-G class I molecules in inhibiting natural killer (NK) cell function, the consequence of abnormal HLA-G expression in malignant cells should be the escape of tumors from immunosurveillance.', select the correct biomedical concept corresponding to 'hla-g class i'. Answer using one of the provided options. | <Options>: A: major histocompatibility complex, class i, f (homo sapiens) (aka major histocompatibility complex, class i, f)
B: major histocompatibility complex, class i, g (homo sapiens) (aka major histocompatibility complex, class i, g)
C: mhc class i polypeptide-related sequence g (pseudogene) (homo sapiens) (aka mhc class i polypeptide-related sequence g (pseudogene))
D: major histocompatibility complex, class i, a (homo sapiens) (aka major histocompatibility complex, class i, a)
E: major histocompatibility complex, class i, e (homo sapiens) (aka major histocompatibility complex, class i, e)
F: None of the above. | B |
<Instruct>: Given the context 'Our analysis of three melanoma cell lines and ex vivo biopsy demonstrated that (i) IGR and M74 human melanoma cell lines exhibit a high level of HLA-G transcription with differential HLA-G isoform transcription and protein expression patterns, (ii) a higher level of HLA-G transcription ex vivo is detected in a skin melanoma metastasis biopsy compared with a healthy skin fragment from the same individual, and (iii) HLA-G protein isoforms other than membrane-bound HLA-G1 protect IGR from NK lysis.', select the correct biomedical concept corresponding to 'hla-g1'. Answer using one of the provided options. | <Options>: A: hla-ha1 (homo sapiens) (aka rho gtpase activating protein 45)
B: hla-g (homo sapiens) (aka major histocompatibility complex, class i, g)
C: hla-z1 (homo sapiens) (aka major histocompatibility complex, class i, z (pseudogene))
D: major histocompatibility complex, class i, a (homo sapiens) (aka major histocompatibility complex, class i, a)
E: major histocompatibility complex, class i, c (homo sapiens) (aka major histocompatibility complex, class i, c)
F: None of the above. | B |
<Instruct>: Given the context 'We have now cloned and characterized a third member of the synapsin gene family, synapsin III, from human DNA.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin i (xenopus tropicalis) (aka synapsin i)
B: synapsin-1 (homo sapiens) (aka synapsin-1)
C: synapsin iii (homo sapiens) (aka synapsin iii)
D: synapsin iii (mus musculus) (aka synapsin iii)
E: sytiii (homo sapiens) (aka synaptotagmin 3)
F: None of the above. | C |
<Instruct>: Given the context 'Synapsin III gives rise to at least one protein isoform, designated synapsin IIIa, in several mammalian species.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin ii (xenopus tropicalis) (aka synapsin ii)
B: sytiii (homo sapiens) (aka synaptotagmin 3)
C: synapsin iii (xenopus tropicalis) (aka synapsin iii)
D: synapsin iii (homo sapiens) (aka synapsin iii)
E: synapsin iii (mus musculus) (aka synapsin iii)
F: None of the above. | D |
<Instruct>: Given the context 'Synapsin III gives rise to at least one protein isoform, designated synapsin IIIa, in several mammalian species.', select the correct biomedical concept corresponding to 'synapsin iiia'. Answer using one of the provided options. | <Options>: A: synapsin i (homo sapiens) (aka synapsin i)
B: synapsin iii (homo sapiens) (aka synapsin iii)
C: syniia (xenopus laevis) (synapsin ii s homeolog (xenopus laevis)) (aka synapsin ii s homeolog)
D: synapsin ii (xenopus tropicalis) (aka synapsin ii)
E: synapsin iii (sus scrofa) (aka synapsin iii)
F: None of the above. | B |
<Instruct>: Given the context 'Synapsin IIIa is associated with synaptic vesicles, and its expression appears to be neuron-specific.', select the correct biomedical concept corresponding to 'synapsin iiia'. Answer using one of the provided options. | <Options>: A: syn1 (xenopus tropicalis) (synapsin i (xenopus tropicalis)) (aka synapsin i)
B: synapsin iii (xenopus tropicalis) (aka synapsin iii)
C: synapsin iii (homo sapiens) (aka synapsin iii)
D: synii (xenopus laevis) (synapsin ii s homeolog (xenopus laevis)) (aka synapsin ii s homeolog)
E: synapsin i (homo sapiens) (aka synapsin i)
F: None of the above. | C |
<Instruct>: Given the context 'The primary structure of synapsin IIIa conforms to the domain model previously described for the synapsin family, with domains A, C, and E exhibiting the highest degree of conservation.', select the correct biomedical concept corresponding to 'synapsin iiia'. Answer using one of the provided options. | <Options>: A: synapsin (xenopus laevis) (synapsin i s homeolog (xenopus laevis)) (aka synapsin i s homeolog)
B: synii (xenopus laevis) (synapsin ii s homeolog (xenopus laevis)) (aka synapsin ii s homeolog)
C: synapsin iii (sus scrofa) (aka synapsin iii)
D: synapsin i (homo sapiens) (aka synapsin i)
E: synapsin iii (homo sapiens) (aka synapsin iii)
F: None of the above. | E |
<Instruct>: Given the context 'Synapsin IIIa contains a novel domain, termed domain J, located between domains C and E. The similarities among synapsins I, II, and III in domain organization, neuron-specific expression, and subcellular localization suggest a possible role for synapsin III in the regulation of neurotransmitter release and synaptogenesis.', select the correct biomedical concept corresponding to 'synapsin iiia'. Answer using one of the provided options. | <Options>: A: synapsin iii (homo sapiens) (aka synapsin iii)
B: synapsin i (homo sapiens) (aka synapsin i)
C: synapsin ii (xenopus tropicalis) (aka synapsin ii)
D: synapsin i (xenopus tropicalis) (aka synapsin i)
E: syniia (xenopus laevis) (synapsin ii s homeolog (xenopus laevis)) (aka synapsin ii s homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Synapsin IIIa contains a novel domain, termed domain J, located between domains C and E. The similarities among synapsins I, II, and III in domain organization, neuron-specific expression, and subcellular localization suggest a possible role for synapsin III in the regulation of neurotransmitter release and synaptogenesis.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin iii (homo sapiens) (aka synapsin iii)
B: synapsin i (homo sapiens) (aka synapsin i)
C: synapsin ii (xenopus tropicalis) (aka synapsin ii)
D: synapsin ii (homo sapiens) (aka synapsin ii)
E: synapsin-1 (homo sapiens) (aka synapsin-1)
F: None of the above. | A |
<Instruct>: Given the context 'The human synapsin III gene is located on chromosome 22q12-13, which has been identified as a possible schizophrenia susceptibility locus.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin i (homo sapiens) (aka synapsin i)
B: synapsin iii (xenopus tropicalis) (aka synapsin iii)
C: synapsin iii (homo sapiens) (aka synapsin iii)
D: synapsin ii (xenopus tropicalis) (aka synapsin ii)
E: sytiii (homo sapiens) (aka synaptotagmin 3)
F: None of the above. | C |
<Instruct>: Given the context 'The human synapsin III gene is located on chromosome 22q12-13, which has been identified as a possible schizophrenia susceptibility locus.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin-1 (homo sapiens) (aka synapsin-1)
B: sytiii (homo sapiens) (aka synaptotagmin 3)
C: synapsin ii (homo sapiens) (aka synapsin ii)
D: synapsin iii (sus scrofa) (aka synapsin iii)
E: synapsin i (xenopus tropicalis) (aka synapsin i)
F: None of the above. | F |
<Instruct>: Given the context 'On the basis of this localization and the well established neurobiological roles of the synapsins, synapsin III represents a candidate gene for schizophrenia.', select the correct biomedical concept corresponding to 'synapsin iii'. Answer using one of the provided options. | <Options>: A: synapsin iii (homo sapiens) (aka synapsin iii)
B: synapsin iii (xenopus tropicalis) (aka synapsin iii)
C: synapsin iii (mus musculus) (aka synapsin iii)
D: synapsin i (xenopus tropicalis) (aka synapsin i)
E: synapsin ii (xenopus tropicalis) (aka synapsin ii)
F: None of the above. | A |
<Instruct>: Given the context 'In this study we investigated the effects of eight muscarinic ligands on the rate constants for endocytosis and recycling of m3 muscarinic acetylcholine receptors in human SH-SY5Y neuroblastoma cells.', select the correct biomedical concept corresponding to 'm3 muscarinic acetylcholine receptors'. Answer using one of the provided options. | <Options>: A: cholinergic receptor, muscarinic 3 (xenopus tropicalis) (aka cholinergic receptor, muscarinic 3)
B: m3 (mus musculus) (relaxin 3 (mus musculus)) (aka relaxin 3)
C: chrm3 (gallus gallus) (aka cholinergic receptor muscarinic 3)
D: chrm3 (mus musculus) (aka cholinergic receptor, muscarinic 3, cardiac)
E: chrm3 (homo sapiens) (aka cholinergic receptor muscarinic 3)
F: None of the above. | E |
<Instruct>: Given the context 'Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.
DNA ligase IV in a complex with XRCC4 is responsible for DNA end-joining in repair of DNA double-strand breaks (DSB) and V(D)J recombination.', select the correct biomedical concept corresponding to 'dna ligase iv'. Answer using one of the provided options. | <Options>: A: dna ligase 4 (homo sapiens) (aka dna ligase 4)
B: dna ligase 4-like (xenopus laevis) (aka dna ligase 4-like)
C: ligase iv, dna, atp-dependent (xenopus tropicalis) (aka ligase iv, dna, atp-dependent)
D: ligase iv (drosophila melanogaster) (aka dna ligase 4)
E: dna ligase iv (arabidopsis thaliana) (aka dna ligase iv)
F: None of the above. | A |
<Instruct>: Given the context 'Non-histone chromosomal proteins HMG1 and 2 enhance ligation reaction of DNA double-strand breaks.
DNA ligase IV in a complex with XRCC4 is responsible for DNA end-joining in repair of DNA double-strand breaks (DSB) and V(D)J recombination.', select the correct biomedical concept corresponding to 'xrcc4'. Answer using one of the provided options. | <Options>: A: xrcc4 (homo sapiens) (aka x-ray repair cross complementing 4)
B: homolog of human dna ligase iv-binding protein xrcc4 (arabidopsis thaliana) (aka dna ligase iv-binding protein)
C: xrcc7 (homo sapiens) (aka protein kinase, dna-activated, catalytic subunit)
D: xrcc5 (homo sapiens) (aka x-ray repair cross complementing 5)
E: xrcc6 (homo sapiens) (aka x-ray repair cross complementing 6)
F: None of the above. | A |
<Instruct>: Given the context 'We found that non-histone chromosomal high mobility group (HMG) proteins 1 and 2 enhanced the ligation of linearized pUC119 DNA with DNA ligase IV from rat liver nuclear extract.', select the correct biomedical concept corresponding to 'dna ligase iv'. Answer using one of the provided options. | <Options>: A: ligase iv, dna, atp-dependent (danio rerio) (aka ligase iv, dna, atp-dependent)
B: ligase iv (drosophila melanogaster) (aka dna ligase 4)
C: dna ligase 4-like (xenopus laevis) (aka dna ligase 4-like)
D: dna ligase 4 (homo sapiens) (aka dna ligase 4)
E: ligase iv, dna, atp-dependent (mus musculus) (aka ligase iv, dna, atp-dependent)
F: None of the above. | D |
<Instruct>: Given the context 'Recombinant HMG2-domain A, B, and (A + B) polypeptides were similarly, but non-identically, effective for the stimulation of DSB ligation reaction.', select the correct biomedical concept corresponding to 'hmg2'. Answer using one of the provided options. | <Options>: A: hmg-2a (homo sapiens) (aka high mobility group box 3)
B: hmg2 (homo sapiens) (aka high mobility group box 2)
C: high mobility group at-hook 2 (homo sapiens) (aka high mobility group at-hook 2)
D: hmg2l1 (homo sapiens) (aka hmg-box containing 4)
E: hmgn2 (homo sapiens) (aka high mobility group nucleosomal binding domain 2)
F: None of the above. | B |
<Instruct>: Given the context 'The DNA end-binding Ku protein singly or in combination with the catalytic component of DNA-dependent protein kinase (DNA-PK) as the DNA-PK holoenzyme was ineffective for the ligation of linearized pUC119 DNA.', select the correct biomedical concept corresponding to 'dna-dependent protein kinase'. Answer using one of the provided options. | <Options>: A: dna-pkcs (xenopus laevis) (aka protein kinase, dna-activated, catalytic subunit l homeolog)
B: protein kinase, dna-activated, catalytic subunit (danio rerio) (aka protein kinase, dna-activated, catalytic subunit)
C: protein kinase, dna-activated, catalytic subunit (homo sapiens) (aka protein kinase, dna-activated, catalytic subunit)
D: protein kinase, dna-activated, catalytic subunit (xenopus tropicalis) (aka protein kinase, dna-activated, catalytic subunit)
E: protein kinase, dna-activated, catalytic subunit (rattus norvegicus) (aka protein kinase, dna-activated, catalytic subunit)
F: None of the above. | C |
<Instruct>: Given the context 'The DNA end-binding Ku protein singly or in combination with the catalytic component of DNA-dependent protein kinase (DNA-PK) as the DNA-PK holoenzyme was ineffective for the ligation of linearized pUC119 DNA.', select the correct biomedical concept corresponding to 'dna-pk'. Answer using one of the provided options. | <Options>: A: dna-pkcs (xenopus laevis) (aka protein kinase, dna-activated, catalytic subunit l homeolog)
B: dna-pkcs (xenopus tropicalis) (aka protein kinase, dna-activated, catalytic subunit)
C: dna-pkc (homo sapiens) (aka protein kinase, dna-activated, catalytic subunit)
D: dna-pkcs (mus musculus) (aka protein kinase, dna activated, catalytic polypeptide)
E: chaperone protein dnak (escherichia coli str. k-12 substr. mg1655) (aka chaperone protein dnak)
F: None of the above. | C |
<Instruct>: Given the context 'The DNA end-binding Ku protein singly or in combination with the catalytic component of DNA-dependent protein kinase (DNA-PK) as the DNA-PK holoenzyme was ineffective for the ligation of linearized pUC119 DNA.', select the correct biomedical concept corresponding to 'dna-pk'. Answer using one of the provided options. | <Options>: A: chaperone protein dnak (escherichia coli str. k-12 substr. mg1655) (aka chaperone protein dnak)
B: protein kinase, dna activated, catalytic polypeptide (mus musculus) (aka protein kinase, dna activated, catalytic polypeptide)
C: dna-pkcs (xenopus laevis) (aka protein kinase, dna-activated, catalytic subunit l homeolog)
D: dnapk (homo sapiens) (aka protein kinase, dna-activated, catalytic subunit)
E: dna-pkcs (xenopus tropicalis) (aka protein kinase, dna-activated, catalytic subunit)
F: None of the above. | D |
<Instruct>: Given the context 'Although the stimulatory effect of HMG1 and 2 on ligation of DSB in vitro was not specific to DNA ligase IV, these results suggest that HMG1 and 2 are involved in the final ligation step in DNA end-joining processes of DSB repair and V(D)J recombination.', select the correct biomedical concept corresponding to 'dna ligase iv'. Answer using one of the provided options. | <Options>: A: dna ligase iv (caenorhabditis elegans) (aka dna ligase iv)
B: dna ligase 4-like (xenopus laevis) (aka dna ligase 4-like)
C: dna ligase 4 (homo sapiens) (aka dna ligase 4)
D: lig4 (saccharomyces cerevisiae s288c) (aka dna ligase (atp) dnl4)
E: dna ligase 4 (oryctolagus cuniculus) (aka dna ligase 4)
F: None of the above. | C |
<Instruct>: Given the context 'Although the stimulatory effect of HMG1 and 2 on ligation of DSB in vitro was not specific to DNA ligase IV, these results suggest that HMG1 and 2 are involved in the final ligation step in DNA end-joining processes of DSB repair and V(D)J recombination.', select the correct biomedical concept corresponding to 'dna ligase iv'. Answer using one of the provided options. | <Options>: A: ligase iv, dna, atp-dependent (mus musculus) (aka ligase iv, dna, atp-dependent)
B: dna ligase iv (caenorhabditis elegans) (aka dna ligase iv)
C: lig4 (saccharomyces cerevisiae s288c) (aka dna ligase (atp) dnl4)
D: ligase iv (drosophila melanogaster) (aka dna ligase 4)
E: dna ligase 4-like (xenopus laevis) (aka dna ligase 4-like)
F: None of the above. | F |
<Instruct>: Given the context 'A search of the yeast data base for a protein homologous to Escherichia coli UDP-N-acetylglucosamine pyrophosphorylase yielded UAP1 (UDP-N-acetylglucosamine pyrophosphorylase), the Saccharomyces cerevisiae gene for UDP-N-acetylglucosamine pyrophosphorylase.', select the correct biomedical concept corresponding to 'uap1'. Answer using one of the provided options. | <Options>: A: uap (homo sapiens) (aka ubiquitin associated protein 1)
B: uap1l1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
C: upf1 regulator of nonsense transcripts homolog (xenopus tropicalis) (aka upf1 regulator of nonsense transcripts homolog)
D: upp1 (homo sapiens) (aka uridine phosphorylase 1)
E: uap1 (saccharomyces cerevisiae s288c) (aka udp-n-acetylglucosamine diphosphorylase)
F: None of the above. | E |
<Instruct>: Given the context 'Sequence analysis revealed that the human UAP1 cDNA was identical to previously reported AGX1.', select the correct biomedical concept corresponding to 'uap1'. Answer using one of the provided options. | <Options>: A: upf1 regulator of nonsense transcripts homolog (xenopus tropicalis) (aka upf1 regulator of nonsense transcripts homolog)
B: uap1l1 (xenopus laevis) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1 l homeolog)
C: uap1 (saccharomyces cerevisiae s288c) (aka udp-n-acetylglucosamine diphosphorylase)
D: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
E: uap1l1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
F: None of the above. | D |
<Instruct>: Given the context 'Sequence analysis revealed that the human UAP1 cDNA was identical to previously reported AGX1.', select the correct biomedical concept corresponding to 'agx1'. Answer using one of the provided options. | <Options>: A: agmx1 (homo sapiens) (aka bruton tyrosine kinase)
B: atx1 (arabidopsis thaliana) (homolog of anti-oxidant 1 (arabidopsis thaliana)) (aka homolog of anti-oxidant 1)
C: agx1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
D: agx1 (saccharomyces cerevisiae s288c) (aka alanine--glyoxylate transaminase)
E: agx1 (xenopus laevis) (udp-n-acetylglucosamine pyrophosphorylase 1 l homeolog (xenopus laevis)) (aka udp-n-acetylglucosamine pyrophosphorylase 1 l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'A null mutation of the S. cerevisiae UAP1 (ScUAP1) gene was lethal, and when expressed under the control of ScUAP1 promoter, both C. albicans and Homo sapiens UAP1 (CaUAP1 and HsUAP1) rescued the ScUAP1-deficient S. cerevisiae cells.', select the correct biomedical concept corresponding to 'uap1'. Answer using one of the provided options. | <Options>: A: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
B: upp1 (homo sapiens) (aka uridine phosphorylase 1)
C: uap1 (saccharomyces cerevisiae s288c) (aka udp-n-acetylglucosamine diphosphorylase)
D: uap (homo sapiens) (aka ubiquitin associated protein 1)
E: urp1 (homo sapiens) (aka ferm domain containing kindlin 1)
F: None of the above. | C |
<Instruct>: Given the context 'A null mutation of the S. cerevisiae UAP1 (ScUAP1) gene was lethal, and when expressed under the control of ScUAP1 promoter, both C. albicans and Homo sapiens UAP1 (CaUAP1 and HsUAP1) rescued the ScUAP1-deficient S. cerevisiae cells.', select the correct biomedical concept corresponding to 'scuap1'. Answer using one of the provided options. | <Options>: A: cluap1 (xenopus tropicalis) (aka clusterin associated protein 1)
B: uca1 (homo sapiens) (aka urothelial cancer associated 1)
C: cluap1 (sus scrofa) (aka clusterin associated protein 1)
D: up1a (xenopus laevis) (uroplakin 1a s homeolog (xenopus laevis)) (aka uroplakin 1a s homeolog)
E: cluap1 (homo sapiens) (aka clusterin associated protein 1)
F: None of the above. | F |
<Instruct>: Given the context 'A null mutation of the S. cerevisiae UAP1 (ScUAP1) gene was lethal, and when expressed under the control of ScUAP1 promoter, both C. albicans and Homo sapiens UAP1 (CaUAP1 and HsUAP1) rescued the ScUAP1-deficient S. cerevisiae cells.', select the correct biomedical concept corresponding to 'scuap1'. Answer using one of the provided options. | <Options>: A: uap1 (sus scrofa) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
B: cluap1 (xenopus tropicalis) (aka clusterin associated protein 1)
C: uca1 (homo sapiens) (aka urothelial cancer associated 1)
D: up1a (xenopus laevis) (uroplakin 1a s homeolog (xenopus laevis)) (aka uroplakin 1a s homeolog)
E: clusterin associated protein 1 (sus scrofa) (aka clusterin associated protein 1)
F: None of the above. | F |
<Instruct>: Given the context 'A null mutation of the S. cerevisiae UAP1 (ScUAP1) gene was lethal, and when expressed under the control of ScUAP1 promoter, both C. albicans and Homo sapiens UAP1 (CaUAP1 and HsUAP1) rescued the ScUAP1-deficient S. cerevisiae cells.', select the correct biomedical concept corresponding to 'hsuap1'. Answer using one of the provided options. | <Options>: A: upla1 (homo sapiens) (aka gjd3 antisense rna 1)
B: cluap1 (homo sapiens) (aka clusterin associated protein 1)
C: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
D: upp1 (homo sapiens) (aka uridine phosphorylase 1)
E: ura1 (homo sapiens) (aka dihydroorotate dehydrogenase (quinone))
F: None of the above. | C |
<Instruct>: Given the context 'A null mutation of the S. cerevisiae UAP1 (ScUAP1) gene was lethal, and when expressed under the control of ScUAP1 promoter, both C. albicans and Homo sapiens UAP1 (CaUAP1 and HsUAP1) rescued the ScUAP1-deficient S. cerevisiae cells.', select the correct biomedical concept corresponding to 'scuap1'. Answer using one of the provided options. | <Options>: A: uca1 (homo sapiens) (aka urothelial cancer associated 1)
B: cluap1 (xenopus laevis) (aka clusterin associated protein 1 l homeolog)
C: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
D: up1a (xenopus laevis) (uroplakin 1a s homeolog (xenopus laevis)) (aka uroplakin 1a s homeolog)
E: cluap1 (homo sapiens) (aka clusterin associated protein 1)
F: None of the above. | F |
<Instruct>: Given the context 'All the recombinant ScUap1p, CaUap1p, and HsUap1p possessed UDP-N-acetylglucosamine pyrophosphorylase activities in vitro.', select the correct biomedical concept corresponding to 'scuap1p'. Answer using one of the provided options. | <Options>: A: cluap1 (xenopus laevis) (aka clusterin associated protein 1 l homeolog)
B: cluap1 (sus scrofa) (aka clusterin associated protein 1)
C: upp1 (sus scrofa) (aka uridine phosphorylase 1)
D: uap1l1 (sus scrofa) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
E: aup1 (sus scrofa) (aka aup1 lipid droplet regulating vldl assembly factor)
F: None of the above. | F |
<Instruct>: Given the context 'All the recombinant ScUap1p, CaUap1p, and HsUap1p possessed UDP-N-acetylglucosamine pyrophosphorylase activities in vitro.', select the correct biomedical concept corresponding to 'hsuap1p'. Answer using one of the provided options. | <Options>: A: azu1p1 (homo sapiens) (aka azurocidin 1 pseudogene 1)
B: upf3a pseudogene 1 (homo sapiens) (aka upf3a pseudogene 1)
C: uba5 pseudogene 1 (homo sapiens) (aka uba5 pseudogene 1)
D: uap1 (sus scrofa) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
E: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
F: None of the above. | E |
<Instruct>: Given the context 'All the recombinant ScUap1p, CaUap1p, and HsUap1p possessed UDP-N-acetylglucosamine pyrophosphorylase activities in vitro.', select the correct biomedical concept corresponding to 'hsuap1p'. Answer using one of the provided options. | <Options>: A: usp37 pseudogene 1 (homo sapiens) (aka usp37 pseudogene 1)
B: uap1l1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
C: uba5p1 (homo sapiens) (aka uba5 pseudogene 1)
D: upf3a pseudogene 1 (homo sapiens) (aka upf3a pseudogene 1)
E: azu1p1 (homo sapiens) (aka azurocidin 1 pseudogene 1)
F: None of the above. | F |
<Instruct>: Given the context 'The yeast Uap1p utilized N-acetylglucosamine-1-phosphate as the substrate, and together with Agm1p, it produced UDP-N-acetylglucosamine from N-acetylglucosamine-6-phosphate.', select the correct biomedical concept corresponding to 'uap1p'. Answer using one of the provided options. | <Options>: A: uap1l1 (xenopus laevis) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1 l homeolog)
B: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
C: uap1 (saccharomyces cerevisiae s288c) (aka udp-n-acetylglucosamine diphosphorylase)
D: uap1 (xenopus laevis) (udp-n-acetylglucosamine pyrophosphorylase 1 s homeolog (xenopus laevis)) (aka udp-n-acetylglucosamine pyrophosphorylase 1 s homeolog)
E: uap1 (xenopus tropicalis) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
F: None of the above. | C |
<Instruct>: Given the context 'The yeast Uap1p utilized N-acetylglucosamine-1-phosphate as the substrate, and together with Agm1p, it produced UDP-N-acetylglucosamine from N-acetylglucosamine-6-phosphate.', select the correct biomedical concept corresponding to 'agm1p'. Answer using one of the provided options. | <Options>: A: agp1 (mus musculus) (anti gp70 immune complex 1 (mus musculus)) (aka anti gp70 immune complex 1)
B: agm1 (homo sapiens) (phosphoglucomutase 3 (homo sapiens)) (aka phosphoglucomutase 3)
C: agm1 (saccharomyces cerevisiae s288c) (aka phosphoacetylglucosamine mutase pcm1)
D: ap3m1 (oryctolagus cuniculus) (aka adaptor related protein complex 3 subunit mu 1)
E: apm1p (saccharomyces cerevisiae s288c) (aka apm1p)
F: None of the above. | C |
<Instruct>: Given the context 'These results demonstrate that the UAP1 genes indeed specify eukaryotic UDP-GlcNAc pyrophosphorylase and that phosphomutase reaction precedes uridyltransfer.', select the correct biomedical concept corresponding to 'uap1'. Answer using one of the provided options. | <Options>: A: upp1 (homo sapiens) (aka uridine phosphorylase 1)
B: uap1l1 (xenopus laevis) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1 l homeolog)
C: uap1 (saccharomyces cerevisiae s288c) (aka udp-n-acetylglucosamine diphosphorylase)
D: uap1l1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
E: uap1 (homo sapiens) (aka udp-n-acetylglucosamine pyrophosphorylase 1)
F: None of the above. | E |
<Instruct>: Given the context 'Sequence comparison with other UDP-sugar pyrophosphorylases revealed that amino acid residues, Gly112, Gly114, Thr115, Arg116, Pro122, and Lys123 of ScUap1p are highly conserved in UDP-sugar pyrophosphorylases reported to date.', select the correct biomedical concept corresponding to 'scuap1p'. Answer using one of the provided options. | <Options>: A: uap1l1 (sus scrofa) (aka udp-n-acetylglucosamine pyrophosphorylase 1 like 1)
B: aup1 (sus scrofa) (aka aup1 lipid droplet regulating vldl assembly factor)
C: upp1 (sus scrofa) (aka uridine phosphorylase 1)
D: cluap1 (xenopus laevis) (aka clusterin associated protein 1 l homeolog)
E: cluap1 (sus scrofa) (aka clusterin associated protein 1)
F: None of the above. | F |
<Instruct>: Given the context 'Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.
Mxi1 belongs to the Mad (Mxi1) family of proteins, which function as potent antagonists of Myc oncoproteins.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi1-rs1 (mus musculus) (aka max interacting protein 1, related sequence 1)
B: max interactor 1, dimerization protein (mus musculus) (aka max interactor 1, dimerization protein)
C: mxi (xenopus laevis) (max interactor 1, dimerization protein s homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein s homeolog)
D: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
E: mxi1 (homo sapiens) (aka max interactor 1, dimerization protein)
F: None of the above. | E |
<Instruct>: Given the context 'Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.
Mxi1 belongs to the Mad (Mxi1) family of proteins, which function as potent antagonists of Myc oncoproteins.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi1 (homo sapiens) (aka max interactor 1, dimerization protein)
B: mxi1-rs1 (mus musculus) (aka max interacting protein 1, related sequence 1)
C: mxi (xenopus laevis) (max interactor 1, dimerization protein s homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein s homeolog)
D: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
E: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.
Mxi1 belongs to the Mad (Mxi1) family of proteins, which function as potent antagonists of Myc oncoproteins.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi (homo sapiens) (aka max interactor 1, dimerization protein)
B: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
C: max interactor 1, dimerization protein (mus musculus) (aka max interactor 1, dimerization protein)
D: mx-1 (mus musculus) (aka mx dynamin-like gtpase 1)
E: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Role of Mxi1 in ageing organ systems and the regulation of normal and neoplastic growth.
Mxi1 belongs to the Mad (Mxi1) family of proteins, which function as potent antagonists of Myc oncoproteins.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
B: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
C: mycl proto-oncogene, bhlh transcription factor (homo sapiens) (aka mycl proto-oncogene, bhlh transcription factor)
D: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
E: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
F: None of the above. | A |
<Instruct>: Given the context 'This antagonism relates partly to their ability to compete with Myc for the protein Max and for consensus DNA binding sites and to recruit transcriptional co-repressors.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: myc proto-oncogene, bhlh transcription factor (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
B: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
C: myc-like oncogene, s-myc protein (mus musculus) (aka myc-like oncogene, s-myc protein)
D: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | A |
<Instruct>: Given the context 'This antagonism relates partly to their ability to compete with Myc for the protein Max and for consensus DNA binding sites and to recruit transcriptional co-repressors.', select the correct biomedical concept corresponding to 'max'. Answer using one of the provided options. | <Options>: A: bhlh (glycine max) (aka transcription factor bhlh30)
B: max homolog 1 (xenopus laevis) (aka max homolog 1)
C: max (homo sapiens) (aka myc associated factor x)
D: basic helix-loop-helix (bhlh) dna-binding protein (glycine max) (aka basic helix-loop-helix (bhlh) dna-binding protein)
E: protein max-like (homo sapiens) (aka protein max-like)
F: None of the above. | C |
<Instruct>: Given the context 'This antagonism relates partly to their ability to compete with Myc for the protein Max and for consensus DNA binding sites and to recruit transcriptional co-repressors.', select the correct biomedical concept corresponding to 'max'. Answer using one of the provided options. | <Options>: A: basic helix-loop-helix transcription factor (glycine max) (aka basic helix-loop-helix transcription factor)
B: bhlh (glycine max) (aka transcription factor bhlh30)
C: homeodomain/homeobox transcription factor (glycine max) (aka homeodomain/homeobox transcription factor)
D: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
E: max (drosophila melanogaster) (males absent on the first (drosophila melanogaster)) (aka males absent on the first)
F: None of the above. | F |
<Instruct>: Given the context 'Mad(Mxi1) proteins have been suggested to be essential in cellular growth control and/or in the induction and maintenance of the differentiated state.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi (xenopus laevis) (max interactor 1, dimerization protein s homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein s homeolog)
B: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
C: mxi1-rs1 (mus musculus) (aka max interacting protein 1, related sequence 1)
D: mxi1 (homo sapiens) (aka max interactor 1, dimerization protein)
E: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'Consistent with these roles, mxi1 may be the tumour-suppressor gene that resides at region 24-26 of the long arm of chromosome 10.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi1 (mus musculus) (aka max interactor 1, dimerization protein)
B: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
C: mxi (homo sapiens) (aka max interactor 1, dimerization protein)
D: mx-1 (mus musculus) (aka mx dynamin-like gtpase 1)
E: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
F: None of the above. | C |
<Instruct>: Given the context 'Here we show that mice lacking Mxi1 exhibit progressive, multisystem abnormalities.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi (homo sapiens) (aka max interactor 1, dimerization protein)
B: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
C: mx-1 (mus musculus) (aka mx dynamin-like gtpase 1)
D: mxi (xenopus laevis) (max interactor 1, dimerization protein s homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein s homeolog)
E: mxi1 (mus musculus) (aka max interactor 1, dimerization protein)
F: None of the above. | E |
<Instruct>: Given the context 'These mice also show increased susceptibility to tumorigenesis either following carcinogen treatment or when also deficient in Ink4a.', select the correct biomedical concept corresponding to 'ink4a'. Answer using one of the provided options. | <Options>: A: ink4d (homo sapiens) (aka cyclin dependent kinase inhibitor 2d)
B: p16ink4 (homo sapiens) (aka cyclin dependent kinase inhibitor 2a)
C: ink4b (homo sapiens) (aka cyclin dependent kinase inhibitor 2b)
D: ink4c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
E: cdkn4 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
F: None of the above. | F |
<Instruct>: Given the context 'This cancer-prone phenotype may correlate with the enhanced ability of several mxi1-deficient cell types, including prostatic epithelium, to proliferate.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi1-rs1 (mus musculus) (aka max interacting protein 1, related sequence 1)
B: mx1 (mus musculus) (aka mx dynamin-like gtpase 1)
C: mxi (xenopus laevis) (max interactor 1, dimerization protein s homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein s homeolog)
D: mxi1 (mus musculus) (aka max interactor 1, dimerization protein)
E: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
F: None of the above. | D |
<Instruct>: Given the context 'Our results show that Mxi1 is involved in the homeostasis of differentiated organ systems, acts as a tumour suppressor in vivo, and engages the Myc network in a functionally relevant manner.', select the correct biomedical concept corresponding to 'mxi1'. Answer using one of the provided options. | <Options>: A: mxi (homo sapiens) (aka max interactor 1, dimerization protein)
B: max interactor 1, dimerization protein (mus musculus) (aka max interactor 1, dimerization protein)
C: mxi (xenopus laevis) (max interactor 1, dimerization protein l homeolog (xenopus laevis)) (aka max interactor 1, dimerization protein l homeolog)
D: mxi1-rs1 (mus musculus) (aka max interacting protein 1, related sequence 1)
E: mx1 (homo sapiens) (aka mx dynamin like gtpase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Our results show that Mxi1 is involved in the homeostasis of differentiated organ systems, acts as a tumour suppressor in vivo, and engages the Myc network in a functionally relevant manner.', select the correct biomedical concept corresponding to 'myc'. Answer using one of the provided options. | <Options>: A: v-myc avian myelocytomatosis viral oncogene homolog (gallus gallus) (aka v-myc avian myelocytomatosis viral oncogene homolog)
B: c-myc (homo sapiens) (aka myc proto-oncogene, bhlh transcription factor)
C: myc (mus musculus) (myelocytomatosis oncogene (mus musculus)) (aka myelocytomatosis oncogene)
D: c-myc-binding protein homolog (glycine max) (aka c-myc-binding protein homolog)
E: v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (mus musculus) (aka v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived)
F: None of the above. | B |
<Instruct>: Given the context 'DNA sequence and muscle-specific expression of human sarcosin transcripts.
', select the correct biomedical concept corresponding to 'sarcosin'. Answer using one of the provided options. | <Options>: A: sarcosin (homo sapiens) (aka kelch like family member 41)
B: sarcospan (bos taurus) (aka sarcospan)
C: sarcc (homo sapiens) (aka purinergic receptor p2y1)
D: sarcosin (rattus norvegicus) (aka kelch-like family member 41)
E: sarcosinemia autosomal recessive (mus musculus) (aka sarcosinemia autosomal recessive)
F: None of the above. | A |
<Instruct>: Given the context 'Consequently, we have termed this novel human sequence sarcosin.', select the correct biomedical concept corresponding to 'sarcosin'. Answer using one of the provided options. | <Options>: A: sarcosin (rattus norvegicus) (aka kelch-like family member 41)
B: sarcospan (homo sapiens) (aka sarcospan)
C: sarcospan (bos taurus) (aka sarcospan)
D: sarcospan (mus musculus) (aka sarcospan)
E: sarcosin (homo sapiens) (aka kelch like family member 41)
F: None of the above. | E |
<Instruct>: Given the context 'Although novel, Southern hybridization analysis demonstrated that the sarcosin sequence has been conserved in several mammalian species.', select the correct biomedical concept corresponding to 'sarcosin'. Answer using one of the provided options. | <Options>: A: sarcosinemia autosomal recessive (mus musculus) (aka sarcosinemia autosomal recessive)
B: sarcc (homo sapiens) (aka purinergic receptor p2y1)
C: sarcosin (danio rerio) (aka kelch-like family member 41b)
D: sarcosin (homo sapiens) (aka kelch like family member 41)
E: sarcospan (homo sapiens) (aka sarcospan)
F: None of the above. | D |
<Instruct>: Given the context 'Although novel, Southern hybridization analysis demonstrated that the sarcosin sequence has been conserved in several mammalian species.', select the correct biomedical concept corresponding to 'sarcosin'. Answer using one of the provided options. | <Options>: A: sarcosin (danio rerio) (aka kelch-like family member 41b)
B: sarcc (homo sapiens) (aka purinergic receptor p2y1)
C: sarcospan (homo sapiens) (aka sarcospan)
D: sarcosin (xenopus tropicalis) (aka kelch like family member 41)
E: sarcospan (mus musculus) (aka sarcospan)
F: None of the above. | F |
<Instruct>: Given the context 'Best macular dystrophy (BMD), also known as vitelliform macular dystrophy (VMD2; OMIM 153700), is an autosomal dominant form of macular degeneration characterized by an abnormal accumulation of lipofuscin within and beneath the retinal pigment epithelium cells.', select the correct biomedical concept corresponding to 'vmd2'. Answer using one of the provided options. | <Options>: A: vm2 (drosophila melanogaster) (aka visible mutation-2)
B: vmd2 (homo sapiens) (aka bestrophin 1)
C: vmd2l3 (homo sapiens) (aka bestrophin 3)
D: vmd4 (homo sapiens) (aka interphotoreceptor matrix proteoglycan 1)
E: vmd2l1 (homo sapiens) (aka bestrophin 2)
F: None of the above. | B |
<Instruct>: Given the context 'In pursuit of the disease gene, we limited the minimum genetic region by recombination breakpoint analysis and mapped to this region a novel retina-specific gene (VMD2).', select the correct biomedical concept corresponding to 'vmd2'. Answer using one of the provided options. | <Options>: A: vm2 (drosophila melanogaster) (aka visible mutation-2)
B: vmd2 (homo sapiens) (aka bestrophin 1)
C: vmd1 (homo sapiens) (aka vitelliform macular dystrophy, atypical)
D: vmd2 (mus musculus) (aka bestrophin 1)
E: vmd4 (homo sapiens) (aka interphotoreceptor matrix proteoglycan 1)
F: None of the above. | B |
<Instruct>: Given the context 'The 3' UTR of the candidate gene contains a region of antisense complementarity to the 3' UTR of the ferritin heavy-chain gene (FTH1), indicating the possibility of antisense interaction between VMD2 and FTH1 transcripts.', select the correct biomedical concept corresponding to 'fth1'. Answer using one of the provided options. | <Options>: A: fthp1 (homo sapiens) (aka ferritin heavy chain 1 pseudogene 5)
B: ft1a (homo sapiens) (aka fucosyltransferase 6)
C: fer1 (drosophila melanogaster) (ferritin 1 heavy chain homologue (drosophila melanogaster)) (aka ferritin 1 heavy chain homologue)
D: fth1p1 (homo sapiens) (aka ferritin heavy chain 1 pseudogene 1)
E: fth (homo sapiens) (aka ferritin heavy chain 1)
F: None of the above. | E |
<Instruct>: Given the context 'The 3' UTR of the candidate gene contains a region of antisense complementarity to the 3' UTR of the ferritin heavy-chain gene (FTH1), indicating the possibility of antisense interaction between VMD2 and FTH1 transcripts.', select the correct biomedical concept corresponding to 'vmd2'. Answer using one of the provided options. | <Options>: A: vmd2 (homo sapiens) (aka bestrophin 1)
B: vmd2 (mus musculus) (aka bestrophin 1)
C: vmd2l2 (homo sapiens) (aka bestrophin 4)
D: vmd1 (homo sapiens) (aka vitelliform macular dystrophy, atypical)
E: mvcd2 (homo sapiens) (aka erythropoietin)
F: None of the above. | A |
<Instruct>: Given the context 'The 3' UTR of the candidate gene contains a region of antisense complementarity to the 3' UTR of the ferritin heavy-chain gene (FTH1), indicating the possibility of antisense interaction between VMD2 and FTH1 transcripts.', select the correct biomedical concept corresponding to 'fth1'. Answer using one of the provided options. | <Options>: A: ft1a (homo sapiens) (aka fucosyltransferase 6)
B: fth1 (homo sapiens) (aka ferritin heavy chain 1)
C: fer1 (drosophila melanogaster) (ferritin 1 heavy chain homologue (drosophila melanogaster)) (aka ferritin 1 heavy chain homologue)
D: fthl1 (homo sapiens) (aka ferritin heavy chain 1 pseudogene 1)
E: fthfd (homo sapiens) (aka aldehyde dehydrogenase 1 family member l1)
F: None of the above. | B |
<Instruct>: Given the context 'BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
The breast cancer specific tumour suppressor protein, BRCA1 (refs 1,2), activates transcription when linked with a DNA-binding domain and is a component of the RNA polymerase II (Pol II) holoenzyme.', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
B: breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans) (aka breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1)
C: brca1 promoter region (homo sapiens) (aka brca1 promoter region)
D: pseudo-brca1 (homo sapiens) (aka brca1 pseudogene 1)
E: brca1 dna repair associated (homo sapiens) (aka brca1 dna repair associated)
F: None of the above. | E |
<Instruct>: Given the context 'BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
The breast cancer specific tumour suppressor protein, BRCA1 (refs 1,2), activates transcription when linked with a DNA-binding domain and is a component of the RNA polymerase II (Pol II) holoenzyme.', select the correct biomedical concept corresponding to 'rna helicase a'. Answer using one of the provided options. | <Options>: A: dexd-box helicase 39a (homo sapiens) (aka dexd-box helicase 39a)
B: swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a containing dead/h box 1 homolog (caenorhabditis elegans) (aka swi/snf-related matrix-associated actin-dependent regulator of chromatin subfamily a containing dead/h box 1 homolog)
C: dead-box helicase 1 (homo sapiens) (aka dead-box helicase 1)
D: ras homolog family member a (homo sapiens) (aka ras homolog family member a)
E: dexh-box helicase 9 (homo sapiens) (aka dexh-box helicase 9)
F: None of the above. | E |
<Instruct>: Given the context 'BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
The breast cancer specific tumour suppressor protein, BRCA1 (refs 1,2), activates transcription when linked with a DNA-binding domain and is a component of the RNA polymerase II (Pol II) holoenzyme.', select the correct biomedical concept corresponding to 'breast cancer specific tumour suppressor protein'. Answer using one of the provided options. | <Options>: A: brcaa1 (homo sapiens) (aka at-rich interaction domain 4b)
B: pseudo-brca1 (homo sapiens) (aka brca1 pseudogene 1)
C: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
D: brca1 (homo sapiens) (aka brca1 dna repair associated)
E: bcds1 (homo sapiens) (cancer, familial, with in vitro radioresistance (homo sapiens)) (aka cancer, familial, with in vitro radioresistance)
F: None of the above. | D |
<Instruct>: Given the context 'BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
The breast cancer specific tumour suppressor protein, BRCA1 (refs 1,2), activates transcription when linked with a DNA-binding domain and is a component of the RNA polymerase II (Pol II) holoenzyme.', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: brisc and brca1 a complex member 1 (homo sapiens) (aka brisc and brca1 a complex member 1)
B: brca1 dna repair associated (homo sapiens) (aka brca1 dna repair associated)
C: breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1 (caenorhabditis elegans) (aka breast cancer type 1 susceptibility protein homolog;ring-type e3 ubiquitin transferase brca1)
D: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
E: pseudo-brca1 (homo sapiens) (aka brca1 pseudogene 1)
F: None of the above. | B |
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