instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', select the correct biomedical concept corresponding to 'mre11'. Answer using one of the provided options. | <Options>: A: mre11 (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
B: mre11 double strand break repair nuclease (homo sapiens) (aka mre11 double strand break repair nuclease)
C: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
D: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
E: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
F: None of the above. | F |
<Instruct>: Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', select the correct biomedical concept corresponding to 'rad50'. Answer using one of the provided options. | <Options>: A: rad50 (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
B: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
C: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
D: rad50 double strand break repair protein (homo sapiens) (aka rad50 double strand break repair protein)
E: rad50 (xenopus laevis) (aka rad50 homolog, double strand break repair protein l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'However, hMre11B does not interact with Mre11, Rad50 and Xrs2.', select the correct biomedical concept corresponding to 'xrs2'. Answer using one of the provided options. | <Options>: A: xrs2 (saccharomyces cerevisiae s288c) (aka xrs2p)
B: xrn2 (homo sapiens) (aka 5'-3' exoribonuclease 2)
C: x-ray repair cross complementing 2 (homo sapiens) (aka x-ray repair cross complementing 2)
D: xrg2 (homo sapiens) (aka xk related x-linked)
E: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
F: None of the above. | A |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'hmre11b'. Answer using one of the provided options. | <Options>: A: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
B: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
C: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
D: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
E: olfactory receptor family 8 subfamily b member 12b (mus musculus) (aka olfactory receptor family 8 subfamily b member 12b)
F: None of the above. | C |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'mre11'. Answer using one of the provided options. | <Options>: A: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
B: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
C: mre11a homolog a, double strand break repair nuclease (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
D: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
E: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
F: None of the above. | F |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'rad50'. Answer using one of the provided options. | <Options>: A: rad50 homolog, double strand break repair protein (xenopus tropicalis) (aka rad50 homolog, double strand break repair protein)
B: dna repair protein rad50-like (xenopus tropicalis) (aka dna repair protein rad50-like)
C: rad50 (saccharomyces cerevisiae s288c) (aka mrx complex dna-binding subunit)
D: rad50 (drosophila melanogaster) (aka rad50)
E: hrad50 (homo sapiens) (aka rad50 double strand break repair protein)
F: None of the above. | C |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'xrs2'. Answer using one of the provided options. | <Options>: A: homolog of x-ray repair cross complementing 2 (arabidopsis thaliana) (aka homolog of x-ray repair cross complementing 2 (xrcc2))
B: dna repair protein xrcc2-like (xenopus tropicalis) (aka dna repair protein xrcc2-like)
C: xrs2 (saccharomyces cerevisiae s288c) (aka xrs2p)
D: xrn2 (saccharomyces cerevisiae s288c) (aka ssrna exonuclease rat1)
E: xrn2 (homo sapiens) (aka 5'-3' exoribonuclease 2)
F: None of the above. | C |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'hmre11b'. Answer using one of the provided options. | <Options>: A: olfactory receptor family 11 subfamily h member 12b (bos taurus) (aka olfactory receptor family 11 subfamily h member 12b)
B: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
C: olfactory receptor family 11 subfamily h member 4b (mus musculus) (aka olfactory receptor family 11 subfamily h member 4b)
D: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
E: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
F: None of the above. | D |
<Instruct>: Given the context 'Hence, the lack of protein-protein interaction between hMre11B and the yeast Mre11, Rad50, and Xrs2 may explain the inability of hMRE11B to complement the yeast mre11 mutants.', select the correct biomedical concept corresponding to 'mre11'. Answer using one of the provided options. | <Options>: A: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
B: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
C: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
D: mre11 (mus musculus) (aka mre11a homolog a, double strand break repair nuclease)
E: mre11 (homo sapiens) (aka mre11 double strand break repair nuclease)
F: None of the above. | F |
<Instruct>: Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', select the correct biomedical concept corresponding to 'hmre11b'. Answer using one of the provided options. | <Options>: A: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
B: olfactory receptor family 11 subfamily h member 4b (mus musculus) (aka olfactory receptor family 11 subfamily h member 4b)
C: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
D: hsd11b (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
E: or9m1b (mus musculus) (aka olfactory receptor family 9 subfamily m member 1b)
F: None of the above. | A |
<Instruct>: Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', select the correct biomedical concept corresponding to 'mre11'. Answer using one of the provided options. | <Options>: A: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
B: mre11 homolog, double strand break repair nuclease (rattus norvegicus) (aka mre11 homolog, double strand break repair nuclease)
C: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
D: mre11 (drosophila melanogaster) (igf-ii mrna-binding protein (drosophila melanogaster)) (aka igf-ii mrna-binding protein)
E: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
F: None of the above. | F |
<Instruct>: Given the context 'We rule out the hypothesis that the lack of interaction and, in turn of complementation, is due to the absence of sequence homology at the C-terminal domain of hMre11B compared to the yeast Mre11.', select the correct biomedical concept corresponding to 'mre11'. Answer using one of the provided options. | <Options>: A: mre11 homolog, double strand break repair nuclease (bos taurus) (aka mre11 homolog, double strand break repair nuclease)
B: mre11 (drosophila melanogaster) (meiotic recombination 11 (drosophila melanogaster)) (aka meiotic recombination 11)
C: mre11 homolog, double strand break repair nuclease (xenopus tropicalis) (aka mre11 homolog, double strand break repair nuclease)
D: mre11 double strand break repair nuclease (homo sapiens) (aka mre11 double strand break repair nuclease)
E: mre11 homolog, double strand break repair nuclease (gallus gallus) (aka mre11 homolog, double strand break repair nuclease)
F: None of the above. | F |
<Instruct>: Given the context 'Instead, we propose that the C-terminus of hMre11B participates in protein-protein interaction and functions in a species-specific manner.', select the correct biomedical concept corresponding to 'hmre11b'. Answer using one of the provided options. | <Options>: A: or2h1b (mus musculus) (aka olfactory receptor family 2 subfamily h member 1b)
B: olfactory receptor family 8 subfamily b member 12b (mus musculus) (aka olfactory receptor family 8 subfamily b member 12b)
C: olfactory receptor family 52 subfamily e member 19b (mus musculus) (aka olfactory receptor family 52 subfamily e member 19b)
D: hmre11b (homo sapiens) (aka mre11 homolog, double strand break repair nuclease pseudogene 1)
E: or4c11b (mus musculus) (aka olfactory receptor family 4 subfamily c member 11b)
F: None of the above. | D |
<Instruct>: Given the context 'XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS.
', select the correct biomedical concept corresponding to 'xce'. Answer using one of the provided options. | <Options>: A: xcel (xenopus tropicalis) (aka carboxyl ester lipase, gene 2)
B: xcca (xenopus laevis) (trna nucleotidyl transferase, cca-adding, 1 s homeolog (xenopus laevis)) (aka trna nucleotidyl transferase, cca-adding, 1 s homeolog)
C: xce (homo sapiens) (x chromosome controlling element (homo sapiens)) (aka x chromosome controlling element)
D: xct (homo sapiens) (aka solute carrier family 7 member 11)
E: xcxcra (xenopus laevis) (aka c-x-c chemokine receptor type a)
F: None of the above. | F |
<Instruct>: Given the context 'The predicted amino-acid sequence of this enzyme, termed XCE, consists of 775 amino-acids with a single putative membrane-spanning region, an N-terminal cytoplasmic domain of 59 residues, and a large luminal domain that contains a characteristic zinc-binding motif.', select the correct biomedical concept corresponding to 'xce'. Answer using one of the provided options. | <Options>: A: xce (mus musculus) (x chromosome inactivation center (mus musculus)) (aka x chromosome inactivation center)
B: xcxcra (xenopus laevis) (aka c-x-c chemokine receptor type a)
C: xce (homo sapiens) (x chromosome inactivation center (homo sapiens)) (aka x chromosome inactivation center)
D: x chromosome controlling element (homo sapiens) (aka x chromosome controlling element)
E: xcenp-e (xenopus laevis) (centromere protein e s homeolog (xenopus laevis)) (aka centromere protein e s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'XCE mRNA was found to be predominantly expressed in the central nervous system, sympathetic ganglia and in uterine subepithelial cells.', select the correct biomedical concept corresponding to 'xce'. Answer using one of the provided options. | <Options>: A: xcel (xenopus tropicalis) (aka carboxyl ester lipase, gene 2)
B: xcxcra (xenopus laevis) (aka c-x-c chemokine receptor type a)
C: xce (homo sapiens) (x chromosome inactivation center (homo sapiens)) (aka x chromosome inactivation center)
D: xce (homo sapiens) (x chromosome controlling element (homo sapiens)) (aka x chromosome controlling element)
E: xce (mus musculus) (x chromosome inactivation center (mus musculus)) (aka x chromosome inactivation center)
F: None of the above. | F |
<Instruct>: Given the context 'Herein we report the cDNA cloning of a human brain 25 kDa lysophospholipid-specific lysophospholipase (hLysoPLA).', select the correct biomedical concept corresponding to 'lysophospholipid-specific lysophospholipase'. Answer using one of the provided options. | <Options>: A: lysophospholipase 2 (xenopus tropicalis) (aka lysophospholipase 2)
B: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
C: lysophospholipase like 1 (homo sapiens) (aka lysophospholipase like 1)
D: patatin like domain 6, lysophospholipase (homo sapiens) (aka patatin like domain 6, lysophospholipase)
E: lysophospholipase 1 (xenopus tropicalis) (aka lysophospholipase 1)
F: None of the above. | B |
<Instruct>: Given the context 'Herein we report the cDNA cloning of a human brain 25 kDa lysophospholipid-specific lysophospholipase (hLysoPLA).', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: spo (homo sapiens) (lactoperoxidase (homo sapiens)) (aka lactoperoxidase)
B: spgyla (homo sapiens) (aka deleted in azoospermia like)
C: hpo (homo sapiens) (aka growth factor, augmenter of liver regeneration)
D: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
E: lpsa (homo sapiens) (aka oncogene liposarcoma (dna segment, single copy, expressed, probes)
F: None of the above. | D |
<Instruct>: Given the context 'The hLysoPLA hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms, and exhibits apparent cooperativity and surface dilution kinetics, but not interfacial activation.', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: spgyla (homo sapiens) (aka deleted in azoospermia like)
B: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
C: ospl (homo sapiens) (aka claudin 10)
D: plosl (homo sapiens) (aka transmembrane immune signaling adaptor tyrobp)
E: lpsa (homo sapiens) (aka oncogene liposarcoma (dna segment, single copy, expressed, probes)
F: None of the above. | B |
<Instruct>: Given the context 'Detailed kinetic analysis indicates that the hLysoPLA binds first to the micellar surface and then to the substrate presented on the surface.', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: plosl (homo sapiens) (aka transmembrane immune signaling adaptor tyrobp)
B: potocki-lupski syndrome (homo sapiens) (aka potocki-lupski syndrome)
C: splash (homo sapiens) (aka phospholipase a2 group iid)
D: spo (homo sapiens) (lactoperoxidase (homo sapiens)) (aka lactoperoxidase)
E: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
F: None of the above. | E |
<Instruct>: Given the context 'The kinetic parameters associated with this surface dilution kinetic model are reported, and it is concluded that hLysoPLA has a single substrate binding site and a surface recognition site.', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: lysopld (homo sapiens) (aka ectonucleotide pyrophosphatase/phosphodiesterase 2)
B: potocki-lupski syndrome (homo sapiens) (aka potocki-lupski syndrome)
C: splash (homo sapiens) (aka phospholipase a2 group iid)
D: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
E: hpo (homo sapiens) (aka growth factor, augmenter of liver regeneration)
F: None of the above. | D |
<Instruct>: Given the context 'In contrast to many non-specific lipolytic enzymes that exhibit lysophospholipase activity, hLysoPLA hydrolyzes only lysophospholipids and has no other significant enzymatic activity.', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: spgyla (homo sapiens) (aka deleted in azoospermia like)
B: plosl (homo sapiens) (aka transmembrane immune signaling adaptor tyrobp)
C: ospl (homo sapiens) (aka claudin 10)
D: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
E: hpo (homo sapiens) (aka growth factor, augmenter of liver regeneration)
F: None of the above. | D |
<Instruct>: Given the context 'Of special interest, hLysoPLA does not act on plasmenylcholine.', select the correct biomedical concept corresponding to 'hlysopla'. Answer using one of the provided options. | <Options>: A: lpsa (homo sapiens) (aka oncogene liposarcoma (dna segment, single copy, expressed, probes)
B: lysopld (homo sapiens) (aka ectonucleotide pyrophosphatase/phosphodiesterase 2)
C: lysophospholipase 1 (homo sapiens) (aka lysophospholipase 1)
D: hpo (homo sapiens) (aka growth factor, augmenter of liver regeneration)
E: splash (homo sapiens) (aka phospholipase a2 group iid)
F: None of the above. | C |
<Instruct>: Given the context 'Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
B: syt1 (homo sapiens) (aka synaptotagmin 1)
C: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
D: synaptoporin (xenopus tropicalis) (aka synaptoporin)
E: syt-vii (homo sapiens) (aka synaptotagmin 7)
F: None of the above. | F |
<Instruct>: Given the context 'Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syt1 (homo sapiens) (aka synaptotagmin 1)
B: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
C: syt1 (xenopus tropicalis) (aka synaptotagmin 1)
D: synaptoporin (xenopus tropicalis) (aka synaptoporin)
E: syt-vii (homo sapiens) (aka synaptotagmin 7)
F: None of the above. | F |
<Instruct>: Given the context 'Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
', select the correct biomedical concept corresponding to 'brm'. Answer using one of the provided options. | <Options>: A: brm (mus musculus) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
B: brms1 like transcriptional repressor (bos taurus) (aka brms1 like transcriptional repressor)
C: brt (mus musculus) (aka tyro3 protein tyrosine kinase 3)
D: brm (drosophila melanogaster) (aka brahma)
E: brm (homo sapiens) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
F: None of the above. | E |
<Instruct>: Given the context 'Functional domains of the SYT and SYT-SSX synovial sarcoma translocation proteins and co-localization with the SNF protein BRM in the nucleus.
', select the correct biomedical concept corresponding to 'brm'. Answer using one of the provided options. | <Options>: A: brm (mus musculus) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
B: brms1 like transcriptional repressor (bos taurus) (aka brms1 like transcriptional repressor)
C: brp (mus musculus) (aka growth differentiation factor 5)
D: brt (mus musculus) (aka tyro3 protein tyrosine kinase 3)
E: brx1, biogenesis of ribosomes (mus musculus) (aka brx1, biogenesis of ribosomes)
F: None of the above. | F |
<Instruct>: Given the context 'The t(X;18)(p11.2;q11.2) chromosomal translocation commonly found in synovial sarcomas fuses the SYT gene on chromosome 18 to either of two similar genes, SSX1 or SSX2, on the X chromosome.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syt1 (xenopus tropicalis) (aka synaptotagmin 1)
B: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
C: syt1 (homo sapiens) (aka synaptotagmin 1)
D: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
E: synaptoporin (xenopus tropicalis) (aka synaptoporin)
F: None of the above. | F |
<Instruct>: Given the context 'The t(X;18)(p11.2;q11.2) chromosomal translocation commonly found in synovial sarcomas fuses the SYT gene on chromosome 18 to either of two similar genes, SSX1 or SSX2, on the X chromosome.', select the correct biomedical concept corresponding to 'ssx1'. Answer using one of the provided options. | <Options>: A: ssg1 (xenopus laevis) (coiled-coil domain containing 80 s homeolog (xenopus laevis)) (aka coiled-coil domain containing 80 s homeolog)
B: ssx1 (homo sapiens) (aka ssx family member 1)
C: ssx3 (homo sapiens) (aka ssx family member 3)
D: ssx5 (homo sapiens) (aka ssx family member 5)
E: ssxp1 (homo sapiens) (aka ssx family member 11, pseudogene)
F: None of the above. | B |
<Instruct>: Given the context 'The t(X;18)(p11.2;q11.2) chromosomal translocation commonly found in synovial sarcomas fuses the SYT gene on chromosome 18 to either of two similar genes, SSX1 or SSX2, on the X chromosome.', select the correct biomedical concept corresponding to 'ssx2'. Answer using one of the provided options. | <Options>: A: ssx2 (homo sapiens) (aka ssx family member 2)
B: sox-2 (xenopus laevis) (sry-box 2 s homeolog (xenopus laevis)) (aka sry-box 2 s homeolog)
C: ssx2b (homo sapiens) (aka ssx family member 2b)
D: ssx2 (saccharomyces cerevisiae s288c) (aka rox3p)
E: protein ssuh2 homolog (xenopus laevis) (aka protein ssuh2 homolog)
F: None of the above. | A |
<Instruct>: Given the context 'The SYT protein appears to act as a transcriptional co-activator and the SSX proteins as co-repressors.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
B: syt-vii (homo sapiens) (aka synaptotagmin 7)
C: syt (xenopus tropicalis) (aka synaptotagmin 1)
D: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
E: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
F: None of the above. | F |
<Instruct>: Given the context 'The SYT protein has a novel conserved 54 amino acid domain at the N-terminus of the protein (the SNH domain) which is found in proteins from a wide variety of species, and a C-terminal domain, rich in glutamine, proline, glycine and tyrosine (the QPGY domain), which contains the transcriptional activator sequences.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syt1 (homo sapiens) (aka synaptotagmin 1)
B: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
C: syt-vii (homo sapiens) (aka synaptotagmin 7)
D: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
E: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'The C-terminal SSX domain present in SYT-SSX translocation protein contributes a transcriptional repressor domain to the protein.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: synaptoporin (xenopus tropicalis) (aka synaptoporin)
B: syt7 (homo sapiens) (aka synaptotagmin 7)
C: syt (xenopus tropicalis) (aka synaptotagmin 1)
D: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
E: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'snf2'. Answer using one of the provided options. | <Options>: A: snf2h (homo sapiens) (aka snf2 related chromatin remodeling atpase 5)
B: smarcf2 (homo sapiens) (aka at-rich interaction domain 1b)
C: snf2l2 (homo sapiens) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
D: swi2 (saccharomyces cerevisiae s288c) (aka swi/snf catalytic subunit snf2)
E: snf2l (homo sapiens) (aka snf2 related chromatin remodeling atpase 1)
F: None of the above. | C |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'brahama'. Answer using one of the provided options. | <Options>: A: nedeba (homo sapiens) (aka atpase h+ transporting v0 subunit a1)
B: bora, aurora kinase a activator (rattus norvegicus) (aka bora, aurora kinase a activator)
C: brd (drosophila melanogaster) (brahma (drosophila melanogaster)) (aka brahma)
D: tmem179ba (danio rerio) (aka transmembrane protein 179ba)
E: bravo (arabidopsis thaliana) (aka myb domain protein 56)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'brm'. Answer using one of the provided options. | <Options>: A: brx1, biogenesis of ribosomes (mus musculus) (aka brx1, biogenesis of ribosomes)
B: brm (homo sapiens) (aka swi/snf related baf chromatin remodeling complex subunit atpase 2)
C: brm1 (mus musculus) (aka brachyury modifier 1)
D: mbr (homo sapiens) (aka translocator protein)
E: brm (drosophila melanogaster) (aka brahma)
F: None of the above. | B |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syt1 (xenopus tropicalis) (aka synaptotagmin 1)
B: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
C: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
D: syt-vii (homo sapiens) (aka synaptotagmin 7)
E: synaptoporin (xenopus tropicalis) (aka synaptoporin)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
B: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
C: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
D: synaptotagmin 1 (xenopus tropicalis) (aka synaptotagmin 1)
E: synaptoporin (xenopus tropicalis) (aka synaptoporin)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
B: syt1 (homo sapiens) (aka synaptotagmin 1)
C: synaptotagmin 1 (xenopus tropicalis) (aka synaptotagmin 1)
D: synaptoporin (xenopus tropicalis) (aka synaptoporin)
E: syt-vii (homo sapiens) (aka synaptotagmin 7)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
B: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
C: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
D: syt-vii (homo sapiens) (aka synaptotagmin 7)
E: synaptoporin (xenopus tropicalis) (aka synaptoporin)
F: None of the above. | F |
<Instruct>: Given the context 'We demonstrate that the human homologue of the SNF2/Brahama protein BRM co-localizes with SYT and SYT-SSX in nuclear speckles, and also interacts with SYT and SYT-SSX proteins in vitro.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syt1 (homo sapiens) (aka synaptotagmin 1)
B: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
C: synaptotagmin 1 (xenopus tropicalis) (aka synaptotagmin 1)
D: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
E: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
F: None of the above. | F |
<Instruct>: Given the context 'This interaction may provide an explanation of how the SYT protein activates gene transcription.', select the correct biomedical concept corresponding to 'syt'. Answer using one of the provided options. | <Options>: A: syn (drosophila melanogaster) (synaptotagmin 1 (drosophila melanogaster)) (aka synaptotagmin 1)
B: syt (xenopus tropicalis) (aka synaptotagmin 1)
C: syt (xenopus laevis) (synaptotagmin 1 s homeolog (xenopus laevis)) (aka synaptotagmin 1 s homeolog)
D: syt-vii (homo sapiens) (aka synaptotagmin 7)
E: synaptotagmin-1 (xenopus tropicalis) (aka synaptotagmin-1)
F: None of the above. | F |
<Instruct>: Given the context 'Identification and expression of delta-isoforms of the multifunctional Ca2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium.
', select the correct biomedical concept corresponding to 'delta-isoforms of the multifunctional ca2+/calmodulin-dependent protein kinase'. Answer using one of the provided options. | <Options>: A: camk2d (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii delta)
B: protein kinase c, delta (mus musculus) (aka protein kinase c, delta)
C: casein kinase 1 delta (homo sapiens) (aka casein kinase 1 delta)
D: protein kinase c delta (xenopus tropicalis) (aka protein kinase c delta)
E: protein kinase c delta (homo sapiens) (aka protein kinase c delta)
F: None of the above. | A |
<Instruct>: Given the context 'In this study, we investigated the spectrum of CaMKII isoforms delta2, delta3, delta4, delta8, and delta9 in human striated muscle tissue.', select the correct biomedical concept corresponding to 'camkii isoforms delta2, delta3, delta4, delta8, and delta9'. Answer using one of the provided options. | <Options>: A: camkiid (drosophila melanogaster) (aka calcium/calmodulin-dependent protein kinase ii)
B: protein kinase c, delta (mus musculus) (aka protein kinase c, delta)
C: camk2d (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii delta)
D: calcium/calmodulin dependent protein kinase ii delta (gallus gallus) (aka calcium/calmodulin dependent protein kinase ii delta)
E: camkiinalpha (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii alpha)
F: None of the above. | C |
<Instruct>: Given the context 'relative to the expression of glyceraldehyde-3-phosphate dehydrogenase in diseased hearts (101. 6+/-11.0% versus 64.9+/-9.9% in the nonfailing group; P < 0.05, n=6).', select the correct biomedical concept corresponding to 'glyceraldehyde-3-phosphate dehydrogenase'. Answer using one of the provided options. | <Options>: A: glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (homo sapiens) (aka glyceraldehyde-3-phosphate dehydrogenase, spermatogenic)
B: gapdh (homo sapiens) (glyceraldehyde-3-phosphate dehydrogenase (homo sapiens)) (aka glyceraldehyde-3-phosphate dehydrogenase)
C: glyceraldehyde-3-phosphate dehydrogenase (sus scrofa) (aka glyceraldehyde-3-phosphate dehydrogenase)
D: glyceraldehyde 3 phosphate dehydrogenase 1 (drosophila melanogaster) (aka glyceraldehyde 3 phosphate dehydrogenase 1)
E: glyceraldehyde-3-phosphate dehydrogenase (xenopus tropicalis) (aka glyceraldehyde-3-phosphate dehydrogenase)
F: None of the above. | B |
<Instruct>: Given the context 'At the protein level, by using a subclass-specific antibody, we observed a similar increase of a delta-CaMKII-specific signal (7.2+/-1.0 versus 3.8+/-0.7 optical density units in the nonfailing group; P < 0.05, n=4 through 6).', select the correct biomedical concept corresponding to 'delta-camkii'. Answer using one of the provided options. | <Options>: A: camkii (drosophila melanogaster) (aka calcium/calmodulin-dependent protein kinase ii)
B: [d]-camkii (mus musculus) (aka calcium/calmodulin-dependent protein kinase ii, delta)
C: camk2 (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)) (aka calcium/calmodulin dependent protein kinase (cam kinase) ii delta)
D: calcium/calmodulin dependent protein kinase ii delta (gallus gallus) (aka calcium/calmodulin dependent protein kinase ii delta)
E: camk2d (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii delta)
F: None of the above. | E |
<Instruct>: Given the context 'Our data characterize for the first time the delta-CaMKII isoform expression pattern in human hearts and demonstrate changes in this expression pattern in heart failure.', select the correct biomedical concept corresponding to 'delta-camkii'. Answer using one of the provided options. | <Options>: A: calcium/calmodulin dependent protein kinase ii delta (gallus gallus) (aka calcium/calmodulin dependent protein kinase ii delta)
B: calcium/calmodulin-dependent protein kinase ii, delta (mus musculus) (aka calcium/calmodulin-dependent protein kinase ii, delta)
C: calcium/calmodulin dependent protein kinase ii delta (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii delta)
D: camkii (drosophila melanogaster) (aka calcium/calmodulin-dependent protein kinase ii)
E: camk2 (xenopus tropicalis) (calcium/calmodulin dependent protein kinase (cam kinase) ii delta (xenopus tropicalis)) (aka calcium/calmodulin dependent protein kinase (cam kinase) ii delta)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
', select the correct biomedical concept corresponding to 'insulin receptor related receptor'. Answer using one of the provided options. | <Options>: A: insulin receptor related receptor (sus scrofa) (aka insulin receptor related receptor)
B: insulin receptor-related receptor (mus musculus) (aka insulin receptor-related receptor)
C: igfir (homo sapiens) (aka insulin like growth factor 1 receptor)
D: insulin receptor related receptor (homo sapiens) (aka insulin receptor related receptor)
E: igf2r (homo sapiens) (aka insulin like growth factor 2 receptor)
F: None of the above. | D |
<Instruct>: Given the context 'Cloning and sequencing of the complete cDNA encoding the human insulin receptor related receptor.
', select the correct biomedical concept corresponding to 'insulin receptor related receptor'. Answer using one of the provided options. | <Options>: A: insr (homo sapiens) (aka insulin receptor)
B: insulin receptor related receptor (xenopus tropicalis) (aka insulin receptor related receptor)
C: igf2r (homo sapiens) (aka insulin like growth factor 2 receptor)
D: insulin receptor-related receptor (rattus norvegicus) (aka insulin receptor-related receptor)
E: insulin receptor related receptor (sus scrofa) (aka insulin receptor related receptor)
F: None of the above. | F |
<Instruct>: Given the context 'The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor with intrinsic tyrosine kinase activity.', select the correct biomedical concept corresponding to 'insulin receptor related receptor'. Answer using one of the provided options. | <Options>: A: insulin receptor related receptor (sus scrofa) (aka insulin receptor related receptor)
B: insulin receptor related receptor (xenopus tropicalis) (aka insulin receptor related receptor)
C: insr (homo sapiens) (aka insulin receptor)
D: insulin receptor-related receptor (rattus norvegicus) (aka insulin receptor-related receptor)
E: insulin receptor related receptor (homo sapiens) (aka insulin receptor related receptor)
F: None of the above. | E |
<Instruct>: Given the context 'The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor with intrinsic tyrosine kinase activity.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: insrr (homo sapiens) (aka insulin receptor related receptor)
B: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
C: insr (homo sapiens) (aka insulin receptor)
D: ifnr (homo sapiens) (aka interferon production regulator)
E: ifngr1 (homo sapiens) (aka interferon gamma receptor 1)
F: None of the above. | A |
<Instruct>: Given the context 'The IRR shares large homology with the insulin and the insulin-like growth factor-1 (IGF-I) receptor with regard to amino acid sequence and protein structure.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: irr (homo sapiens) (aka insulin receptor related receptor)
B: insr (homo sapiens) (aka insulin receptor)
C: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
D: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
E: ifngr (homo sapiens) (aka interferon gamma receptor 1)
F: None of the above. | A |
<Instruct>: Given the context 'So far, only a partial human sequence containing the complete 3' end has been reported, although the full-length human IRR cDNA had been used for transfection studies and functional analysis of the receptor.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
B: insulin receptor related receptor (homo sapiens) (aka insulin receptor related receptor)
C: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
D: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
E: ifngr (homo sapiens) (aka interferon gamma receptor 1)
F: None of the above. | B |
<Instruct>: Given the context 'We have isolated a full-length human IRR cDNA and report on the 5' translated and untranslated region of the human IRR gene.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
B: irr (homo sapiens) (aka insulin receptor related receptor)
C: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
D: ifnr (homo sapiens) (aka interferon production regulator)
E: ifngr (homo sapiens) (aka interferon gamma receptor 1)
F: None of the above. | B |
<Instruct>: Given the context 'We have isolated a full-length human IRR cDNA and report on the 5' translated and untranslated region of the human IRR gene.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: insr (homo sapiens) (aka insulin receptor)
B: ifngr (homo sapiens) (aka interferon gamma receptor 1)
C: insrr (homo sapiens) (aka insulin receptor related receptor)
D: ifnr (homo sapiens) (aka interferon production regulator)
E: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
F: None of the above. | C |
<Instruct>: Given the context 'The full length IRR sequence contains 4150 bases and shares a high degree of homology with the guinea pig IRR cDNA sequence and rat IRR sequences that had been reported earlier on by others.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: ifnr (homo sapiens) (aka interferon production regulator)
B: irr (homo sapiens) (aka insulin receptor related receptor)
C: ifngr1 (homo sapiens) (aka interferon gamma receptor 1)
D: insr (homo sapiens) (aka insulin receptor)
E: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
F: None of the above. | B |
<Instruct>: Given the context 'The full length IRR sequence contains 4150 bases and shares a high degree of homology with the guinea pig IRR cDNA sequence and rat IRR sequences that had been reported earlier on by others.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: ifnr (homo sapiens) (aka interferon production regulator)
B: insr (homo sapiens) (aka insulin receptor)
C: ifngr1 (homo sapiens) (aka interferon gamma receptor 1)
D: insrr (homo sapiens) (aka insulin receptor related receptor)
E: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
F: None of the above. | F |
<Instruct>: Given the context 'The full length IRR sequence contains 4150 bases and shares a high degree of homology with the guinea pig IRR cDNA sequence and rat IRR sequences that had been reported earlier on by others.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: insr (homo sapiens) (aka insulin receptor)
B: ifngr (homo sapiens) (aka interferon gamma receptor 1)
C: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
D: ifnr (homo sapiens) (aka interferon production regulator)
E: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
F: None of the above. | F |
<Instruct>: Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
B: ifnr (homo sapiens) (aka interferon production regulator)
C: insulin receptor related receptor (homo sapiens) (aka insulin receptor related receptor)
D: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
E: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
F: None of the above. | C |
<Instruct>: Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
B: insr (homo sapiens) (aka insulin receptor)
C: ifngr1 (homo sapiens) (aka interferon gamma receptor 1)
D: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
E: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
F: None of the above. | F |
<Instruct>: Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: insr (homo sapiens) (aka insulin receptor)
B: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
C: ifnr (homo sapiens) (aka interferon production regulator)
D: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
E: irr (homo sapiens) (aka insulin receptor related receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Sequencing of the IRR cDNA revealed that the human IRR cDNA contains 341 bases corresponding to the IRR 5' end in addition to the bases that had been reported on before.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
B: insr (homo sapiens) (aka insulin receptor)
C: irr (homo sapiens) (aka insulin receptor related receptor)
D: il1r (homo sapiens) (aka interleukin 1 receptor type 1)
E: ip10-r (homo sapiens) (aka c-x-c motif chemokine receptor 3)
F: None of the above. | C |
<Instruct>: Given the context 'The full length cDNA for the human IRR can now be used for functional expression studies and to elucidate the nature of the ligand for this receptor type.', select the correct biomedical concept corresponding to 'irr'. Answer using one of the provided options. | <Options>: A: insulin receptor related receptor (homo sapiens) (aka insulin receptor related receptor)
B: ifnr (homo sapiens) (aka interferon production regulator)
C: il1r3 (homo sapiens) (aka interleukin 1 receptor accessory protein)
D: ifngr (homo sapiens) (aka interferon gamma receptor 1)
E: insr (homo sapiens) (aka insulin receptor)
F: None of the above. | A |
<Instruct>: Given the context 'The deduced amino acids sequence shows an overall homology of 48% with the human renal NPT1 protein.', select the correct biomedical concept corresponding to 'npt1'. Answer using one of the provided options. | <Options>: A: npt1 (homo sapiens) (aka solute carrier family 17 member 1)
B: npt2 (homo sapiens) (aka solute carrier family 34 member 1)
C: solute carrier family 11 member 1 (homo sapiens) (aka solute carrier family 11 member 1)
D: npat (homo sapiens) (aka nuclear protein, coactivator of histone transcription)
E: solute carrier family 1 member 1 (homo sapiens) (aka solute carrier family 1 member 1)
F: None of the above. | A |
<Instruct>: Given the context 'Thus, this gene may code for intestinal type NPT or closely related proteins.', select the correct biomedical concept corresponding to 'intestinal type npt'. Answer using one of the provided options. | <Options>: A: npt4 (homo sapiens) (aka solute carrier family 17 member 3)
B: nptn-it1 (homo sapiens) (aka nptn intronic transcript 1)
C: npt2 (rattus norvegicus) (aka solute carrier family 34 member 1)
D: npt2 (homo sapiens) (aka solute carrier family 34 member 1)
E: npat (homo sapiens) (aka nuclear protein, coactivator of histone transcription)
F: None of the above. | F |
<Instruct>: Given the context 'Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.
', select the correct biomedical concept corresponding to 'tgf-beta 1'. Answer using one of the provided options. | <Options>: A: transforming growth factor beta 1 (bos taurus) (aka transforming growth factor beta 1)
B: interferon beta 1 (homo sapiens) (aka interferon beta 1)
C: tgfb1 (homo sapiens) (aka transforming growth factor beta 1)
D: transforming growth factor beta receptor 1 (homo sapiens) (aka transforming growth factor beta receptor 1)
E: il1-beta (homo sapiens) (aka interleukin 1 beta)
F: None of the above. | C |
<Instruct>: Given the context 'Cutting edge: immature dendritic cells generated from monocytes in the presence of TGF-beta 1 express functional C-C chemokine receptor 6.
', select the correct biomedical concept corresponding to 'c-c chemokine receptor 6'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor 8 (homo sapiens) (aka c-c motif chemokine receptor 8)
B: c-c motif chemokine receptor 7 (homo sapiens) (aka c-c motif chemokine receptor 7)
C: c-c ckr-6 (homo sapiens) (aka c-c motif chemokine receptor 6)
D: c-x-c motif chemokine receptor 6 (homo sapiens) (aka c-x-c motif chemokine receptor 6)
E: None of the above. | C |
<Instruct>: Given the context 'Although CD34+ progenitor-derived immature dendritic cells (DCs) express CCR6, several recent studies reported that monocyte-derived immature DCs do not do so.', select the correct biomedical concept corresponding to 'ccr6'. Answer using one of the provided options. | <Options>: A: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6)
B: ccr-8 (homo sapiens) (aka c-c motif chemokine receptor 8)
C: cc-ckr-6 (homo sapiens) (aka c-c motif chemokine receptor 6)
D: None of the above. | C |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'gm-csf'. Answer using one of the provided options. | <Options>: A: multi-csf (homo sapiens) (aka interleukin 3)
B: colony stimulating factor 1 (homo sapiens) (aka colony stimulating factor 1)
C: gmcsf (homo sapiens) (aka colony stimulating factor 2)
D: colony stimulating factor 3 (homo sapiens) (aka colony stimulating factor 3)
E: gm-csf (mus musculus) (aka colony stimulating factor 2 (granulocyte-macrophage))
F: None of the above. | C |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'il-4'. Answer using one of the provided options. | <Options>: A: il-4 (bos taurus) (aka interleukin 4)
B: bolf1 (human gammaherpesvirus 4) (aka tegument protein ul37)
C: bllf1 (human gammaherpesvirus 4) (aka glycoprotein 350)
D: bdlf4 (human gammaherpesvirus 4) (aka protein ul92)
E: il4 (homo sapiens) (aka interleukin 4)
F: None of the above. | E |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'il-4'. Answer using one of the provided options. | <Options>: A: bdlf4 (human gammaherpesvirus 4) (aka protein ul92)
B: il4 (bos taurus) (aka interleukin 4)
C: interleukin 5 (homo sapiens) (aka interleukin 5)
D: bolf1 (human gammaherpesvirus 4) (aka tegument protein ul37)
E: bllf1 (human gammaherpesvirus 4) (aka glycoprotein 350)
F: None of the above. | F |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'tgf-beta 1'. Answer using one of the provided options. | <Options>: A: transforming growth factor beta 1 (bos taurus) (aka transforming growth factor beta 1)
B: interferon beta 1 (homo sapiens) (aka interferon beta 1)
C: tgfb1 (homo sapiens) (aka transforming growth factor beta 1)
D: transforming growth factor beta receptor 1 (homo sapiens) (aka transforming growth factor beta receptor 1)
E: transforming growth factor beta 1 (xenopus tropicalis) (aka transforming growth factor beta 1)
F: None of the above. | C |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'liver and activation-regulated chemokine'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine ligand 13 (homo sapiens) (aka c-c motif chemokine ligand 13)
B: rantes (homo sapiens) (aka c-c motif chemokine ligand 5)
C: ccl16 (homo sapiens) (aka c-c motif chemokine ligand 16)
D: 6ckine (homo sapiens) (aka c-c motif chemokine ligand 21)
E: c-x-c motif chemokine ligand 3 (homo sapiens) (aka c-x-c motif chemokine ligand 3)
F: None of the above. | F |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'larc'. Answer using one of the provided options. | <Options>: A: larc (xenopus tropicalis) (aka c-c motif chemokine ligand 20)
B: lnccrla (homo sapiens) (aka myo1d divergent transcript)
C: lnc-rhl (homo sapiens) (aka lncrna regulator of hepatic lineages 1)
D: lar (homo sapiens) (aka protein tyrosine phosphatase receptor type f)
E: larc (homo sapiens) (aka c-c motif chemokine ligand 20)
F: None of the above. | E |
<Instruct>: Given the context 'We observed that DCs generated from monocytes in the presence of GM-CSF, IL-4, and TGF-beta 1 consistently responded to liver and activation-regulated chemokine (LARC, also known as macrophage inflammatory protein-3 alpha).', select the correct biomedical concept corresponding to 'macrophage inflammatory protein-3 alpha'. Answer using one of the provided options. | <Options>: A: mip3 (homo sapiens) (aka c-c motif chemokine ligand 23)
B: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3)
C: c-x-c motif chemokine ligand 3 (homo sapiens) (aka c-x-c motif chemokine ligand 3)
D: mip-3-alpha (homo sapiens) (aka c-c motif chemokine ligand 20)
E: mcp-3 (homo sapiens) (aka c-c motif chemokine ligand 7)
F: None of the above. | D |
<Instruct>: Given the context 'These immature DCs expressed one class of high-affinity binding sites for LARC, and expressed both CCR6 mRNA and protein.', select the correct biomedical concept corresponding to 'larc'. Answer using one of the provided options. | <Options>: A: larc (xenopus tropicalis) (aka c-c motif chemokine ligand 20)
B: larc (homo sapiens) (aka c-c motif chemokine ligand 20)
C: lncarsr (homo sapiens) (aka lncrna regulator of akt signaling associated with hcc and rcc)
D: larc (mus musculus) (aka c-c motif chemokine ligand 20)
E: lard (homo sapiens) (aka tnf receptor superfamily member 25)
F: None of the above. | B |
<Instruct>: Given the context 'These immature DCs expressed one class of high-affinity binding sites for LARC, and expressed both CCR6 mRNA and protein.', select the correct biomedical concept corresponding to 'ccr6'. Answer using one of the provided options. | <Options>: A: cc-ckr-6 (homo sapiens) (aka c-c motif chemokine receptor 6)
B: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6)
C: ccr-8 (homo sapiens) (aka c-c motif chemokine receptor 8)
D: None of the above. | A |
<Instruct>: Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', select the correct biomedical concept corresponding to 'larc'. Answer using one of the provided options. | <Options>: A: lncsrlr (homo sapiens) (aka lncrna sorafenib resistance in renal cell carcinoma associated)
B: lar (homo sapiens) (aka protein tyrosine phosphatase receptor type f)
C: larc (mus musculus) (aka c-c motif chemokine ligand 20)
D: larc (homo sapiens) (aka c-c motif chemokine ligand 20)
E: lnc-rhl (homo sapiens) (aka lncrna regulator of hepatic lineages 1)
F: None of the above. | D |
<Instruct>: Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', select the correct biomedical concept corresponding to 'ccr6'. Answer using one of the provided options. | <Options>: A: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6)
B: cc-ckr-8 (homo sapiens) (aka c-c motif chemokine receptor 8)
C: ccr-6 (homo sapiens) (aka c-c motif chemokine receptor 6)
D: None of the above. | C |
<Instruct>: Given the context 'Therefore, LARC-CCR6 interaction presumably also contributes to the regulation of trafficking of monocyte-derived DCs, and utilization of TGF-beta can potentially provide a ready source of CCR6+ monocyte-derived DCs for therapeutic purposes.', select the correct biomedical concept corresponding to 'ccr6'. Answer using one of the provided options. | <Options>: A: ccr-8 (homo sapiens) (aka c-c motif chemokine receptor 8)
B: cmkbr6 (homo sapiens) (aka c-c motif chemokine receptor 6)
C: cxcr6 (homo sapiens) (aka c-x-c motif chemokine receptor 6)
D: None of the above. | B |
<Instruct>: Given the context 'Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkn-alpha (homo sapiens) (aka protein kinase n1)
B: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
C: protein kinase c beta (bos taurus) (aka protein kinase c beta)
D: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
E: pkbbeta (homo sapiens) (aka akt serine/threonine kinase 2)
F: None of the above. | F |
<Instruct>: Given the context 'Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
C: pkn-alpha (homo sapiens) (aka protein kinase n1)
D: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
E: pkbbeta (homo sapiens) (aka akt serine/threonine kinase 2)
F: None of the above. | F |
<Instruct>: Given the context 'Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
', select the correct biomedical concept corresponding to 'pknalpha'. Answer using one of the provided options. | <Options>: A: pkn-alpha (homo sapiens) (aka protein kinase n1)
B: prkr (homo sapiens) (aka eukaryotic translation initiation factor 2 alpha kinase 2)
C: pkn-alpha (xenopus laevis) (aka protein kinase n1 l homeolog)
D: prkn (homo sapiens) (aka parkin rbr e3 ubiquitin protein ligase)
E: pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster)) (aka protein kinase n)
F: None of the above. | A |
<Instruct>: Given the context 'The cDNA clone encoding a novel isoform of protein kinase PKN, termed PKNbeta, was isolated from a HeLa cDNA library.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
C: pkn-alpha (homo sapiens) (aka protein kinase n1)
D: protein kinase c beta (homo sapiens) (aka protein kinase c beta)
E: pkbb (homo sapiens) (aka akt serine/threonine kinase 2)
F: None of the above. | F |
<Instruct>: Given the context 'PKNbeta had high sequence homology with PKNalpha, originally isolated PKN, especially in the repeats of charged amino acid-rich region with leucine-zipper like sequences (CZ region/HR1), in the carboxyl-terminal catalytic domain, and in approximately 130 amino acid stretch (D region/HR2), located between CZ region/HR1 and the catalytic domain.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
B: pkgb (homo sapiens) (aka junction plakoglobin)
C: pkc-beta (homo sapiens) (aka protein kinase c beta)
D: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
E: pkn-alpha (homo sapiens) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'PKNbeta had high sequence homology with PKNalpha, originally isolated PKN, especially in the repeats of charged amino acid-rich region with leucine-zipper like sequences (CZ region/HR1), in the carboxyl-terminal catalytic domain, and in approximately 130 amino acid stretch (D region/HR2), located between CZ region/HR1 and the catalytic domain.', select the correct biomedical concept corresponding to 'pknalpha'. Answer using one of the provided options. | <Options>: A: pkn1 (homo sapiens) (aka protein kinase n1)
B: pkn-alpha (xenopus tropicalis) (aka protein kinase n1)
C: pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster)) (aka protein kinase n)
D: pku-alpha (homo sapiens) (aka tousled like kinase 2)
E: prkn (homo sapiens) (aka parkin rbr e3 ubiquitin protein ligase)
F: None of the above. | A |
<Instruct>: Given the context 'However, the amino acid sequence of PKNbeta differed from that of PKNalpha in the region immediately amino-terminal to the catalytic domain, which contained two distinct proline-rich sequences consistent with the class II consensus sequence, PXXPXR, for binding to SH3 domain.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: protein kinase c beta (bos taurus) (aka protein kinase c beta)
C: pkn-alpha (homo sapiens) (aka protein kinase n1)
D: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
E: protein kinase c beta (homo sapiens) (aka protein kinase c beta)
F: None of the above. | F |
<Instruct>: Given the context 'However, the amino acid sequence of PKNbeta differed from that of PKNalpha in the region immediately amino-terminal to the catalytic domain, which contained two distinct proline-rich sequences consistent with the class II consensus sequence, PXXPXR, for binding to SH3 domain.', select the correct biomedical concept corresponding to 'pknalpha'. Answer using one of the provided options. | <Options>: A: pku-alpha (homo sapiens) (aka tousled like kinase 2)
B: prkr (homo sapiens) (aka eukaryotic translation initiation factor 2 alpha kinase 2)
C: prkn (homo sapiens) (aka parkin rbr e3 ubiquitin protein ligase)
D: pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster)) (aka protein kinase n)
E: pkn (homo sapiens) (aka protein kinase n1)
F: None of the above. | E |
<Instruct>: Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkbb (homo sapiens) (aka akt serine/threonine kinase 2)
B: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
C: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
D: protein kinase c beta (homo sapiens) (aka protein kinase c beta)
E: protein kinase c beta (bos taurus) (aka protein kinase c beta)
F: None of the above. | F |
<Instruct>: Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', select the correct biomedical concept corresponding to 'pknalpha'. Answer using one of the provided options. | <Options>: A: prkr (homo sapiens) (aka eukaryotic translation initiation factor 2 alpha kinase 2)
B: pkn2 (homo sapiens) (aka protein kinase n2)
C: pkn-alpha (xenopus laevis) (aka protein kinase n1 l homeolog)
D: pkn-alpha (xenopus tropicalis) (aka protein kinase n1)
E: pkn1 (homo sapiens) (aka protein kinase n1)
F: None of the above. | E |
<Instruct>: Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: prkcb (homo sapiens) (aka protein kinase c beta)
C: protein kinase c, beta (rattus norvegicus) (aka protein kinase c, beta)
D: pkbbeta (homo sapiens) (aka akt serine/threonine kinase 2)
E: protein kinase c beta (bos taurus) (aka protein kinase c beta)
F: None of the above. | F |
<Instruct>: Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
C: protein kinase c beta (bos taurus) (aka protein kinase c beta)
D: pkn-alpha (homo sapiens) (aka protein kinase n1)
E: pkc-beta (homo sapiens) (aka protein kinase c beta)
F: None of the above. | F |
<Instruct>: Given the context 'Distribution of PKNbeta differed from that of PKNalpha in the following two respects: (1) Northern blotting indicated that PKNbeta mRNA could not be detected in human adult tissues, but was expressed abundantly in human cancer cell lines; (2) immunochemical analysis indicated that PKNbeta localized in nucleus and perinuclear Golgi apparatus, and was almost absent in cytoplasmic region in NIH3T3 cells.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: pkgb (homo sapiens) (aka junction plakoglobin)
B: pkbb (homo sapiens) (aka akt serine/threonine kinase 2)
C: prkcb (homo sapiens) (aka protein kinase c beta)
D: pkn-alpha (homo sapiens) (aka protein kinase n1)
E: protein kinase c beta (bos taurus) (aka protein kinase c beta)
F: None of the above. | F |
<Instruct>: Given the context 'Recombinant PKNbeta expressed in COS7 cells displayed autophosphorylation and peptide kinase activity, but was found to be significantly less responsive to arachidonic acid than PKNalpha.', select the correct biomedical concept corresponding to 'pknbeta'. Answer using one of the provided options. | <Options>: A: protein kinase c beta (bos taurus) (aka protein kinase c beta)
B: cdc42 binding protein kinase beta (bos taurus) (aka cdc42 binding protein kinase beta)
C: pkbb (homo sapiens) (aka akt serine/threonine kinase 2)
D: pkc-beta (homo sapiens) (aka protein kinase c beta)
E: pkn-alpha (homo sapiens) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'Recombinant PKNbeta expressed in COS7 cells displayed autophosphorylation and peptide kinase activity, but was found to be significantly less responsive to arachidonic acid than PKNalpha.', select the correct biomedical concept corresponding to 'pknalpha'. Answer using one of the provided options. | <Options>: A: prkr (homo sapiens) (aka eukaryotic translation initiation factor 2 alpha kinase 2)
B: prkn (homo sapiens) (aka parkin rbr e3 ubiquitin protein ligase)
C: pkn2 (homo sapiens) (aka protein kinase n2)
D: pkn-alpha (xenopus laevis) (aka protein kinase n1 l homeolog)
E: pkn (homo sapiens) (aka protein kinase n1)
F: None of the above. | E |
<Instruct>: Given the context 'Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.
', select the correct biomedical concept corresponding to 'ndp'. Answer using one of the provided options. | <Options>: A: ndnf (homo sapiens) (aka neuron derived neurotrophic factor)
B: ndc1 transmembrane nucleoporin (homo sapiens) (aka ndc1 transmembrane nucleoporin)
C: norrin cystine knot growth factor ndp (homo sapiens) (aka norrin cystine knot growth factor ndp)
D: ndpp (homo sapiens) (aka caspase recruitment domain family member 8)
E: ndn (homo sapiens) (aka necdin, mage family member)
F: None of the above. | C |
<Instruct>: Given the context 'Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis.
', select the correct biomedical concept corresponding to 'norrin'. Answer using one of the provided options. | <Options>: A: nynrin (rattus norvegicus) (aka nyn domain and retroviral integrase containing)
B: ninein-like (rattus norvegicus) (aka ninein-like)
C: norrin cystine knot growth factor ndp (rattus norvegicus) (aka norrin cystine knot growth factor ndp)
D: norrin cystine knot growth factor ndp (homo sapiens) (aka norrin cystine knot growth factor ndp)
E: norbin (rattus norvegicus) (aka neurochondrin)
F: None of the above. | D |
<Instruct>: Given the context 'Both carried a missense mutation within the NDP gene on chromosome Xp11.2.', select the correct biomedical concept corresponding to 'ndp'. Answer using one of the provided options. | <Options>: A: ndc1 transmembrane nucleoporin (homo sapiens) (aka ndc1 transmembrane nucleoporin)
B: ndpkd (homo sapiens) (aka nme/nm23 nucleoside diphosphate kinase 4)
C: norrin cystine knot growth factor ndp (homo sapiens) (aka norrin cystine knot growth factor ndp)
D: ndn (homo sapiens) (aka necdin, mage family member)
E: ndp (xenopus tropicalis) (aka norrin cystine knot growth factor ndp)
F: None of the above. | C |
<Instruct>: Given the context 'Subsequently analysis of the retinas of nine enucleated eyes from males with Coats' disease demonstrated in one a somatic mutation in the NDP gene which was not present within non-retinal tissue.', select the correct biomedical concept corresponding to 'ndp'. Answer using one of the provided options. | <Options>: A: ndnf (homo sapiens) (aka neuron derived neurotrophic factor)
B: naked cuticle homolog 1 (xenopus tropicalis) (aka naked cuticle homolog 1)
C: ndp (rattus norvegicus) (aka norrin cystine knot growth factor ndp)
D: norrin cystine knot growth factor ndp (homo sapiens) (aka norrin cystine knot growth factor ndp)
E: ndpp (homo sapiens) (aka caspase recruitment domain family member 8)
F: None of the above. | D |
<Instruct>: Given the context 'We suggest that Coats' telangiectasis is secondary to somatic mutation in the NDP gene which results in a deficiency of norrin (the protein product of the NDP gene) within the developing retina.', select the correct biomedical concept corresponding to 'ndp'. Answer using one of the provided options. | <Options>: A: ndn (homo sapiens) (aka necdin, mage family member)
B: ndp (homo sapiens) (aka norrin cystine knot growth factor ndp)
C: ndnf (homo sapiens) (aka neuron derived neurotrophic factor)
D: naked cuticle homolog 1 (xenopus tropicalis) (aka naked cuticle homolog 1)
E: ndp (xenopus tropicalis) (aka norrin cystine knot growth factor ndp)
F: None of the above. | B |
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