instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
|---|---|---|
<Instruct>: Given the context 'This finding also confirms the presence of a larger linkage group on chromosome 19, including now the loci for apoE, Le, C3, LW, Lu, Se, H, PEPD, myotonic dystrophy (DM), neurofibromatosis (NF) and familial hypercholesterolemia (FHC).', select the correct biomedical concept corresponding to 'fhc'. Answer using one of the provided options. | <Options>: A: fh (homo sapiens) (complement factor h (homo sapiens)) (aka complement factor h)
B: fhdc1 (homo sapiens) (aka fh2 domain containing 1)
C: fhh (homo sapiens) (aka calcium sensing receptor)
D: fh3 (homo sapiens) (aka proprotein convertase subtilisin/kexin type 9)
E: fhf1 (homo sapiens) (aka fibroblast growth factor 12)
F: None of the above. | F |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'lw'. Answer using one of the provided options. | <Options>: A: lvwm (homo sapiens) (aka eukaryotic translation initiation factor 2b subunit epsilon)
B: lws (homo sapiens) (aka rna, u4atac small nuclear)
C: gwl (bos taurus) (aka microtubule associated serine/threonine kinase like)
D: lwr (drosophila melanogaster) (aka lesswright)
E: lw (homo sapiens) (aka intercellular adhesion molecule 4 (landsteiner-wiener blood group))
F: None of the above. | E |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'lewis blood group'. Answer using one of the provided options. | <Options>: A: selectin e (bos taurus) (aka selectin e)
B: selectin l (bos taurus) (aka selectin l)
C: ly6e (bos taurus) (aka lymphocyte antigen 6 family member e)
D: lectin, galactoside-binding-like l homeolog (xenopus laevis) (aka lectin, galactoside-binding-like l homeolog)
E: basal cell adhesion molecule (lutheran blood group) l homeolog (xenopus laevis) (aka basal cell adhesion molecule (lutheran blood group) l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'lw'. Answer using one of the provided options. | <Options>: A: lw (drosophila melanogaster) (aka long wing)
B: lw (homo sapiens) (aka intercellular adhesion molecule 4 (landsteiner-wiener blood group))
C: lvwm (homo sapiens) (aka eukaryotic translation initiation factor 2b subunit epsilon)
D: lw-1 (homo sapiens) (aka heat shock transcription factor family, x-linked 1)
E: opn1lw (homo sapiens) (aka opsin 1, long wave sensitive)
F: None of the above. | B |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'le'. Answer using one of the provided options. | <Options>: A: les (homo sapiens) (aka fucosyltransferase 3 (lewis blood group))
B: lipase, endothelial l homeolog (xenopus laevis) (aka lipase, endothelial l homeolog)
C: le (mus musculus) (aka hps4, biogenesis of lysosomal organelles complex 3 subunit 2)
D: leo1 homolog, paf1/rna polymerase ii complex component s homeolog (xenopus laevis) (aka leo1 homolog, paf1/rna polymerase ii complex component s homeolog)
E: leo1 homolog, paf1/rna polymerase ii complex component l homeolog (xenopus laevis) (aka leo1 homolog, paf1/rna polymerase ii complex component l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'le'. Answer using one of the provided options. | <Options>: A: les (homo sapiens) (aka fucosyltransferase 3 (lewis blood group))
B: le (mus musculus) (aka hps4, biogenesis of lysosomal organelles complex 3 subunit 2)
C: leo1 homolog, paf1/rna polymerase ii complex component (xenopus tropicalis) (aka leo1 homolog, paf1/rna polymerase ii complex component)
D: lipase, endothelial l homeolog (xenopus laevis) (aka lipase, endothelial l homeolog)
E: leb (homo sapiens) (aka mucin 5ac, oligomeric mucus/gel-forming)
F: None of the above. | A |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'c3'. Answer using one of the provided options. | <Options>: A: complement component 3 precursor pseudogene (homo sapiens) (aka complement component 3 precursor pseudogene)
B: complement c3 (homo sapiens) (aka complement c3)
C: apolipoprotein c3 (homo sapiens) (aka apolipoprotein c3)
D: complement component 3 (gallus gallus) (aka complement component 3)
E: c3 (bos taurus) (aka complement c3)
F: None of the above. | B |
<Instruct>: Given the context 'Linkage of LW with the Lewis blood group locus could not be definitely established by the present family data, but small positive scores between LW and Le suggest that the Le locus is situated outside the C3-LW region.', select the correct biomedical concept corresponding to 'lw'. Answer using one of the provided options. | <Options>: A: lw (homo sapiens) (aka intercellular adhesion molecule 4 (landsteiner-wiener blood group))
B: lw-1 (homo sapiens) (aka heat shock transcription factor family, x-linked 1)
C: wd repeat-containing protein lwd2-like (glycine max) (aka wd repeat-containing protein lwd2-like)
D: lwr (drosophila melanogaster) (aka lesswright)
E: gwl (bos taurus) (aka microtubule associated serine/threonine kinase like)
F: None of the above. | A |
<Instruct>: Given the context 'Human beta-nerve growth factor gene sequence highly homologous to that of mouse.
', select the correct biomedical concept corresponding to 'beta-nerve growth factor'. Answer using one of the provided options. | <Options>: A: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
B: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
C: nerve growth factor b (beta polypeptide) (danio rerio) (aka nerve growth factor b (beta polypeptide))
D: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
E: ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | E |
<Instruct>: Given the context 'Even so, beta-NGF comprises only approximately 0.1% of the protein in this small gland, which has made the study of this polypeptide difficult.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
B: ngfb (bos taurus) (aka nerve growth factor)
C: beta-ngf (homo sapiens) (aka nerve growth factor)
D: beta-ngf (rattus norvegicus) (aka nerve growth factor)
E: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
F: None of the above. | C |
<Instruct>: Given the context 'The amino acid sequence of the mouse NGF beta-chain has been determined and some information has been obtained regarding the size of a mouse precursor molecule, pro-beta-NGF, but little was known about the structure and relatedness of beta-NGF from other vertebrates.', select the correct biomedical concept corresponding to 'ngf beta'. Answer using one of the provided options. | <Options>: A: neuropeptide b (rattus norvegicus) (aka neuropeptide b)
B: ngfb (bos taurus) (aka nerve growth factor)
C: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
D: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
E: neuromedin b (rattus norvegicus) (aka neuromedin b)
F: None of the above. | F |
<Instruct>: Given the context 'The amino acid sequence of the mouse NGF beta-chain has been determined and some information has been obtained regarding the size of a mouse precursor molecule, pro-beta-NGF, but little was known about the structure and relatedness of beta-NGF from other vertebrates.', select the correct biomedical concept corresponding to 'ngf beta'. Answer using one of the provided options. | <Options>: A: lymphotoxin beta (homo sapiens) (aka lymphotoxin beta)
B: lymphotoxin beta (rattus norvegicus) (aka lymphotoxin beta)
C: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
D: ngfb (bos taurus) (aka nerve growth factor)
E: beta-ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | F |
<Instruct>: Given the context 'The amino acid sequence of the mouse NGF beta-chain has been determined and some information has been obtained regarding the size of a mouse precursor molecule, pro-beta-NGF, but little was known about the structure and relatedness of beta-NGF from other vertebrates.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (rattus norvegicus) (aka nerve growth factor)
B: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
C: ngf (homo sapiens) (aka nerve growth factor)
D: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
E: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
F: None of the above. | C |
<Instruct>: Given the context 'The amino acid sequence of the mouse NGF beta-chain has been determined and some information has been obtained regarding the size of a mouse precursor molecule, pro-beta-NGF, but little was known about the structure and relatedness of beta-NGF from other vertebrates.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
B: ngfb (rattus norvegicus) (aka nerve growth factor)
C: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
D: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
E: ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | E |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: ngf (homo sapiens) (aka nerve growth factor)
B: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
C: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
D: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
E: ngfb (bos taurus) (aka nerve growth factor)
F: None of the above. | F |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: ngf (homo sapiens) (aka nerve growth factor)
B: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
C: beta-ngf (rattus norvegicus) (aka nerve growth factor)
D: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
E: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
F: None of the above. | A |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
B: ngf (homo sapiens) (aka nerve growth factor)
C: ngfb (rattus norvegicus) (aka nerve growth factor)
D: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
E: brain derived neurotrophic factor (homo sapiens) (aka brain derived neurotrophic factor)
F: None of the above. | B |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: beta-ngf (rattus norvegicus) (aka nerve growth factor)
B: ngfb (bos taurus) (aka nerve growth factor)
C: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
D: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
E: neurotrophin 6 beta (pseudogene) (homo sapiens) (aka neurotrophin 6 beta (pseudogene))
F: None of the above. | F |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
B: ngfb (bos taurus) (aka nerve growth factor)
C: beta-ngf (rattus norvegicus) (aka nerve growth factor)
D: beta-ngf (xenopus tropicalis) (aka nerve growth factor)
E: ngf (homo sapiens) (aka nerve growth factor)
F: None of the above. | E |
<Instruct>: Given the context 'Here we describe the isolation of mouse beta-NGF complementary DNA (cDNA) and present its nucleotide sequence, which predicts a prepro-beta-NGF molecule of Mr 27,000 (27K) and a pro-beta-NGF molecule of Mr 25K. We have used the mouse beta-NGF cDNA clone to isolate the human beta-NGF gene, the coding regions of which are highly homologous to the mouse prepro-beta-NGF nucleotide and amino acid sequences.', select the correct biomedical concept corresponding to 'beta-ngf'. Answer using one of the provided options. | <Options>: A: brain-derived neurotrophic factor (rattus norvegicus) (aka brain-derived neurotrophic factor)
B: beta-ngf (homo sapiens) (aka nerve growth factor)
C: ngfb (rattus norvegicus) (aka nerve growth factor)
D: ngfib (homo sapiens) (aka nuclear receptor subfamily 4 group a member 1)
E: ngfb (bos taurus) (aka nerve growth factor)
F: None of the above. | F |
<Instruct>: Given the context 'Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa.
', select the correct biomedical concept corresponding to 'alpha subunit of the rod cgmp-gated channel'. Answer using one of the provided options. | <Options>: A: achra (homo sapiens) (aka cholinergic receptor nicotinic alpha 1 subunit)
B: alpha1aar (homo sapiens) (aka adrenoceptor alpha 1a)
C: cyclic nucleotide gated channel subunit alpha 1 (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 1)
D: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
E: protein kinase camp-dependent type i regulatory subunit alpha (homo sapiens) (aka protein kinase camp-dependent type i regulatory subunit alpha)
F: None of the above. | F |
<Instruct>: Given the context 'Mutations in the genes encoding two proteins of the retinal rod phototransduction cascade, opsin and the beta subunit of rod cGMP phosphodiesterase, cause retinitis pigmentosa (RP) in some families.', select the correct biomedical concept corresponding to 'beta subunit of rod cgmp phosphodiesterase'. Answer using one of the provided options. | <Options>: A: pdeivb (homo sapiens) (aka phosphodiesterase 4b)
B: pde3b (homo sapiens) (aka phosphodiesterase 3b)
C: pde8b (homo sapiens) (aka phosphodiesterase 8b)
D: gmp-pdebeta (homo sapiens) (aka phosphodiesterase 6b)
E: phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus) (aka phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide)
F: None of the above. | D |
<Instruct>: Given the context 'Mutations in the genes encoding two proteins of the retinal rod phototransduction cascade, opsin and the beta subunit of rod cGMP phosphodiesterase, cause retinitis pigmentosa (RP) in some families.', select the correct biomedical concept corresponding to 'beta subunit of rod cgmp phosphodiesterase'. Answer using one of the provided options. | <Options>: A: pde1b (homo sapiens) (aka phosphodiesterase 1b)
B: pdeivb (homo sapiens) (aka phosphodiesterase 4b)
C: pde8b (homo sapiens) (aka phosphodiesterase 8b)
D: pde3b (homo sapiens) (aka phosphodiesterase 3b)
E: phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide (mus musculus) (aka phosphodiesterase 6b, cgmp, rod receptor, beta polypeptide)
F: None of the above. | F |
<Instruct>: Given the context 'We screened 94 unrelated patients with autosomal dominant RP and 173 unrelated patients with autosomal recessive RP for mutations in the gene encoding the alpha subunit of the rod cGMP-gated cation channel.', select the correct biomedical concept corresponding to 'alpha subunit of the rod cgmp-gated cation channel'. Answer using one of the provided options. | <Options>: A: protein kinase camp-dependent type i regulatory subunit alpha (homo sapiens) (aka protein kinase camp-dependent type i regulatory subunit alpha)
B: cyclic nucleotide gated channel alpha 1 (xenopus tropicalis) (aka cyclic nucleotide gated channel alpha 1)
C: rcncalpha (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 1)
D: cyclic nucleotide gated channel subunit alpha 2 (homo sapiens) (aka cyclic nucleotide gated channel subunit alpha 2)
E: calcium voltage-gated channel subunit alpha1 a (homo sapiens) (aka calcium voltage-gated channel subunit alpha1 a)
F: None of the above. | F |
<Instruct>: Given the context 'Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
', select the correct biomedical concept corresponding to 'cellular apoptosis susceptibility gene'. Answer using one of the provided options. | <Options>: A: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
B: ovarian cancer, epithelial, susceptibility to (homo sapiens) (aka ovarian cancer, epithelial, susceptibility to)
C: cuta divalent cation tolerance homolog (sus scrofa) (aka cuta divalent cation tolerance homolog)
D: caspr (homo sapiens) (aka contactin associated protein 1)
E: cas (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and characterization of a cellular apoptosis susceptibility gene, the human homologue to the yeast chromosome segregation gene CSE1.
', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
B: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
C: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
D: csec (homo sapiens) (aka sialic acid acetylesterase)
E: cse1l (homo sapiens) (aka chromosome segregation 1 like)
F: None of the above. | B |
<Instruct>: Given the context 'We report here that one of these fragments is an antisense fragment of a gene homologous to the essential yeast chromosome segregation gene CSE1.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
B: cse-c (homo sapiens) (aka sialic acid acetylesterase)
C: cse1 (homo sapiens) (aka chromosome segregation 1 like)
D: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
E: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
F: None of the above. | A |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
B: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
C: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
D: csec (homo sapiens) (aka sialic acid acetylesterase)
E: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
B: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
C: cas1p (homo sapiens) (aka cas1 domain sialic acid o acetyltransferase 1)
D: cas1 (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
E: casr (homo sapiens) (aka calcium sensing receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cellular apoptosis susceptibility gene'. Answer using one of the provided options. | <Options>: A: cancer susceptibility 11 (homo sapiens) (aka cancer susceptibility 11)
B: hearing loss, cisplatin-induced, susceptibility to (homo sapiens) (aka hearing loss, cisplatin-induced, susceptibility to)
C: atherosclerosis susceptibility (lipoprotein associated) (homo sapiens) (aka atherosclerosis susceptibility (lipoprotein associated))
D: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
E: caspr (homo sapiens) (aka contactin associated protein 1)
F: None of the above. | D |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: bcar1 scaffold protein, cas family member (gallus gallus) (aka bcar1 scaffold protein, cas family member)
B: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
C: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
D: casa (homo sapiens) (aka casein alpha s1)
E: casr (homo sapiens) (aka calcium sensing receptor)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 (escherichia coli str. k-12 substr. mg1655) (aka type i-e crispr system cascade subunit casa)
B: cse1l (homo sapiens) (aka chromosome segregation 1 like)
C: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
D: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
E: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
B: cse1l (homo sapiens) (aka chromosome segregation 1 like)
C: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
D: csec (homo sapiens) (aka sialic acid acetylesterase)
E: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning and analysis of the full-length cDNA of the human CSE1 homologue, which we name CAS for cellular apoptosis susceptibility gene, reveals a protein coding region with similar length (971 amino acids for CAS, 960 amino acids for CSE1) and 59% overall protein homology to the yeast CSE1 protein.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
B: cse1 chromosome segregation 1-like s homeolog (xenopus laevis) (aka cse1 chromosome segregation 1-like s homeolog)
C: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
D: csec (homo sapiens) (aka sialic acid acetylesterase)
E: cse1l (homo sapiens) (aka chromosome segregation 1 like)
F: None of the above. | F |
<Instruct>: Given the context 'The conservation of this gene indicates it has an important function in human cells consistent with the essential role of CSE1 in yeast.', select the correct biomedical concept corresponding to 'cse1'. Answer using one of the provided options. | <Options>: A: cse1 (saccharomyces cerevisiae s288c) (aka importin-alpha export receptor)
B: cse1 chromosome segregation 1-like (xenopus tropicalis) (aka cse1 chromosome segregation 1-like)
C: csen (homo sapiens) (aka potassium voltage-gated channel interacting protein 3)
D: cse-c (homo sapiens) (aka sialic acid acetylesterase)
E: cse (drosophila melanogaster) (chromosome segregation 1 (drosophila melanogaster)) (aka chromosome segregation 1)
F: None of the above. | A |
<Instruct>: Given the context 'CAS is highly expressed in human tumor cell lines and in human testis and fetal liver, tissues that contain actively dividing cells.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
B: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
C: casr (homo sapiens) (aka calcium sensing receptor)
D: cas (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
E: cas1p (homo sapiens) (aka cas1 domain sialic acid o acetyltransferase 1)
F: None of the above. | B |
<Instruct>: Given the context 'Furthermore, CAS expression increases when resting human fibroblasts are induced to proliferate and decreases when they are growth-arrested.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
B: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
C: casa (homo sapiens) (aka casein alpha s1)
D: cas1p (homo sapiens) (aka cas1 domain sialic acid o acetyltransferase 1)
E: bcar1 scaffold protein, cas family member (gallus gallus) (aka bcar1 scaffold protein, cas family member)
F: None of the above. | B |
<Instruct>: Given the context 'Thus, CAS appears to play an important role in both toxin and tumor necrosis factor-mediated cell death, as well as in cell proliferation.', select the correct biomedical concept corresponding to 'cas'. Answer using one of the provided options. | <Options>: A: cas (homo sapiens) (bcar1 scaffold protein, cas family member (homo sapiens)) (aka bcar1 scaffold protein, cas family member)
B: cas3 (homo sapiens) (aka embryonal fyn-associated substrate)
C: casr (homo sapiens) (aka calcium sensing receptor)
D: cas1p (homo sapiens) (aka cas1 domain sialic acid o acetyltransferase 1)
E: cas (homo sapiens) (chromosome segregation 1 like (homo sapiens)) (aka chromosome segregation 1 like)
F: None of the above. | E |
<Instruct>: Given the context 'They were all located on the long arm of chromosome 17, in loci located between q11 and q21.3, a region known to contain the c-erbB-2 oncogene and the BRCA1 breast carcinomas, and overexpression of three of them was dependent on gene amplification in breast cancer cell lines.', select the correct biomedical concept corresponding to 'c-erbb-2'. Answer using one of the provided options. | <Options>: A: erb-b2 receptor tyrosine kinase 3 (homo sapiens) (aka erb-b2 receptor tyrosine kinase 3)
B: her-2/neu (homo sapiens) (aka erb-b2 receptor tyrosine kinase 2)
C: None of the above. | B |
<Instruct>: Given the context 'They were all located on the long arm of chromosome 17, in loci located between q11 and q21.3, a region known to contain the c-erbB-2 oncogene and the BRCA1 breast carcinomas, and overexpression of three of them was dependent on gene amplification in breast cancer cell lines.', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
B: brca1 dna repair associated (homo sapiens) (aka brca1 dna repair associated)
C: brca1 promoter region (homo sapiens) (aka brca1 promoter region)
D: brca1p1 (homo sapiens) (aka brca1 pseudogene 1)
E: brisc and brca1 a complex member 1 (homo sapiens) (aka brisc and brca1 a complex member 1)
F: None of the above. | B |
<Instruct>: Given the context 'Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.
', select the correct biomedical concept corresponding to 'striatum-enriched phosphatase'. Answer using one of the provided options. | <Options>: A: phosphoethanolamine/phosphocholine phosphatase (sus scrofa) (aka phosphoethanolamine/phosphocholine phosphatase)
B: ec-ptp (homo sapiens) (aka protein tyrosine phosphatase receptor type r)
C: ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like (sus scrofa) (aka ectonucleotide pyrophosphatase/phosphodiesterase family member 7-like)
D: o-sialoglycoprotein endopeptidase (sus scrofa) (aka o-sialoglycoprotein endopeptidase)
E: ptpstep (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
F: None of the above. | E |
<Instruct>: Given the context 'Molecular cloning of the human homolog of a striatum-enriched phosphatase (STEP) gene and chromosomal mapping of the human and murine loci.
', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
B: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
C: stp-1 (sus scrofa) (aka transition protein 1)
D: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
E: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
F: None of the above. | E |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
B: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
C: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
D: try (sus scrofa) (aka serine protease 2)
E: step (drosophila melanogaster) (aka steppke)
F: None of the above. | B |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
B: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
C: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
D: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
E: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
F: None of the above. | B |
<Instruct>: Given the context 'By using a combination of somatic cell hybrid analysis and fluorescence in situ hybridization, we have mapped the human STEP locus to chromosome 11p15.2-p15.1 and the murine STEP gene to chromosome 7B3-B5.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
B: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
C: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
D: step (drosophila melanogaster) (aka steppke)
E: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
F: None of the above. | F |
<Instruct>: Given the context 'These are two regions of known conserved synteny, providing further evidence that the human STEP is a true homolog of the murine STEP gene.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: step1 (arabidopsis thaliana) (aka 31-kda rna binding protein)
B: step (drosophila melanogaster) (aka steppke)
C: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
D: stp-1 (sus scrofa) (aka transition protein 1)
E: stepp (homo sapiens) (aka peroxisomal testis enriched protein 1)
F: None of the above. | C |
<Instruct>: Given the context 'These are two regions of known conserved synteny, providing further evidence that the human STEP is a true homolog of the murine STEP gene.', select the correct biomedical concept corresponding to 'step'. Answer using one of the provided options. | <Options>: A: try (sus scrofa) (aka serine protease 2)
B: tppp (sus scrofa) (aka tubulin polymerization promoting protein)
C: step (mus musculus) (aka protein tyrosine phosphatase, non-receptor type 5)
D: step (homo sapiens) (aka protein tyrosine phosphatase non-receptor type 5)
E: tptep (homo sapiens) (aka tpte2 pseudogene 4)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2.
', select the correct biomedical concept corresponding to 'atp synthase oscp subunit'. Answer using one of the provided options. | <Options>: A: atp synthase peripheral stalk subunit oscp (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
B: atp synthase peripheral stalk subunit oscp (oryctolagus cuniculus) (aka atp synthase peripheral stalk subunit oscp)
C: atp synthase subunit o, mitochondrial (caenorhabditis elegans) (aka atp synthase subunit o, mitochondrial)
D: atp synthase peripheral stalk subunit oscp (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
E: atp synthase peripheral stalk subunit oscp (sus scrofa) (aka atp synthase peripheral stalk subunit oscp)
F: None of the above. | D |
<Instruct>: Given the context 'Cloning of the cDNA for the human ATP synthase OSCP subunit (ATP5O) by exon trapping and mapping to chromosome 21q22.1-q22.2.
', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5po (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
B: atp5lp5 (homo sapiens) (aka atp synthase membrane subunit g pseudogene 5)
C: atp5i (homo sapiens) (aka atp synthase membrane subunit e)
D: atp5h (homo sapiens) (aka atp synthase peripheral stalk subunit d)
E: atp5o (mus musculus) (aka atp synthase peripheral stalk subunit oscp)
F: None of the above. | A |
<Instruct>: Given the context 'We subsequently cloned the full-length human ATP synthase OSCP cDNA (GDB/HGMW approved name ATP50) from infant brain and muscle libraries and determined its nucleotide and deduced amino acid sequence (EMBL/GenBank Accession No. X83218).', select the correct biomedical concept corresponding to 'atp synthase oscp'. Answer using one of the provided options. | <Options>: A: atp synthase peripheral stalk subunit oscp (xenopus tropicalis) (aka atp synthase peripheral stalk subunit oscp)
B: atpo (xenopus laevis) (atp synthase peripheral stalk subunit oscp s homeolog (xenopus laevis)) (aka atp synthase peripheral stalk subunit oscp s homeolog)
C: atp synthase subunit o, mitochondrial (caenorhabditis elegans) (aka atp synthase subunit o, mitochondrial)
D: atp synthase peripheral stalk subunit oscp (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
E: atp5s (oryctolagus cuniculus) (aka distal membrane arm assembly component 2 like)
F: None of the above. | D |
<Instruct>: Given the context 'We subsequently cloned the full-length human ATP synthase OSCP cDNA (GDB/HGMW approved name ATP50) from infant brain and muscle libraries and determined its nucleotide and deduced amino acid sequence (EMBL/GenBank Accession No. X83218).', select the correct biomedical concept corresponding to 'atp50'. Answer using one of the provided options. | <Options>: A: atpo (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
B: atpase (homo sapiens) (aka dynein axonemal heavy chain 8)
C: transmembrane protein 50 homolog (glycine max) (aka transmembrane protein 50 homolog)
D: atpl (homo sapiens) (aka atpase h+ transporting v0 subunit c)
E: atp20 (saccharomyces cerevisiae s288c) (aka f1f0 atp synthase subunit g)
F: None of the above. | A |
<Instruct>: Given the context 'The human ATP5O gene is located at 21q22.1-q22.2, just proximal to D21S17, in YACs 860G11 and 838C7 of the Chumakov et al.', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5l (homo sapiens) (aka atp synthase membrane subunit g)
B: atp5o (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
C: atp5i (homo sapiens) (aka atp synthase membrane subunit e)
D: atp5h (homo sapiens) (aka atp synthase peripheral stalk subunit d)
E: atp5e (homo sapiens) (aka atp synthase f1 subunit epsilon)
F: None of the above. | B |
<Instruct>: Given the context 'This ATP5O subunit is a key structural component of the stalk of the mitochondrial respiratory chain F1F0-ATP synthase and as such may contribute in a gene dosage-dependent manner to the phenotype of Down syndrome (trisomy 21).', select the correct biomedical concept corresponding to 'atp5o'. Answer using one of the provided options. | <Options>: A: atp5i (homo sapiens) (aka atp synthase membrane subunit e)
B: atp5 (homo sapiens) (aka atp synthase peripheral stalk subunit f6)
C: atp5po (homo sapiens) (aka atp synthase peripheral stalk subunit oscp)
D: atp5lp5 (homo sapiens) (aka atp synthase membrane subunit g pseudogene 5)
E: atp5l (homo sapiens) (aka atp synthase membrane subunit g)
F: None of the above. | C |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
B: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
C: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
D: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
E: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
F: None of the above. | A |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'mitochondrial carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 4 (homo sapiens) (aka carbonic anhydrase 4)
B: ca-xiv (mus musculus) (aka carbonic anhydrase 14)
C: carbonic anhydrase vb, mitochondrial (xenopus tropicalis) (aka carbonic anhydrase vb, mitochondrial)
D: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
E: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
F: None of the above. | D |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'mitochondrial carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5a, mitochondrial-like (homo sapiens) (aka carbonic anhydrase 5a, mitochondrial-like)
B: carbonic anhydrase vb, mitochondrial (xenopus tropicalis) (aka carbonic anhydrase vb, mitochondrial)
C: ca-xiv (mus musculus) (aka carbonic anhydrase 14)
D: carbonic anhydrase 5a, mitochondrial (mus musculus) (aka carbonic anhydrase 5a, mitochondrial)
E: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
F: None of the above. | F |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'carbonic anhydrase v'. Answer using one of the provided options. | <Options>: A: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
B: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
C: carbonic anhydrase 7 (homo sapiens) (aka carbonic anhydrase 7)
D: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
E: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
F: None of the above. | B |
<Instruct>: Given the context 'Genomic organization of the human gene (CA5) and pseudogene for mitochondrial carbonic anhydrase V and their localization to chromosomes 16q and 16p.
Carbonic anhydrase V (CA V) is expressed in mitochondrial matrix in liver and several other tissues.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
B: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
C: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
D: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
E: coagulation factor v (homo sapiens) (aka coagulation factor v)
F: None of the above. | B |
<Instruct>: Given the context 'It is of interest for its putative roles in providing bicarbonate to carbamoyl phosphate synthetase for ureagenesis and to pyruvate carboxylase for gluconeogenesis and its possible importance in explaining certain inherited metabolic disorders with hyperammonemia and hypoglycemia.', select the correct biomedical concept corresponding to 'pyruvate carboxylase'. Answer using one of the provided options. | <Options>: A: phosphoenolpyruvate carboxykinase 1 (homo sapiens) (aka phosphoenolpyruvate carboxykinase 1)
B: pyruvate carboxylase (bos taurus) (aka pyruvate carboxylase)
C: pyruvate carboxylase (homo sapiens) (aka pyruvate carboxylase)
D: pyruvate carboxylase (oryctolagus cuniculus) (aka pyruvate carboxylase)
E: pyruvate carboxylase 1 (saccharomyces cerevisiae s288c) (aka pyruvate carboxylase 1)
F: None of the above. | C |
<Instruct>: Given the context 'Following the recent characterization of the cDNA for human CA V, we report the isolation of the human gene from two lambda genomic libraries and its characterization.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: coagulation factor v (homo sapiens) (aka coagulation factor v)
B: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
C: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
D: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
E: ca5b (xenopus laevis) (aka carbonic anhydrase vb, mitochondrial l homeolog)
F: None of the above. | D |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept corresponding to 'ca v'. Answer using one of the provided options. | <Options>: A: ca5 (gallus gallus) (aka carbonic anhydrase 5a)
B: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
C: ca5a (homo sapiens) (aka carbonic anhydrase 5a)
D: coagulation factor v (homo sapiens) (aka coagulation factor v)
E: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
F: None of the above. | C |
<Instruct>: Given the context 'The CA V gene (CA5) is approximately 50 kb long and contains 7 exons and 6 introns.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
B: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
C: ca7.5 (mus musculus) (aka dna segment, ca7.5)
D: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
E: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
F: None of the above. | E |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca ii'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 2 (homo sapiens) (aka carbonic anhydrase 2)
B: ca-i (homo sapiens) (aka carbonic anhydrase 1)
C: ca-2 (xenopus laevis) (carbonic anhydrase 2 s homeolog (xenopus laevis)) (aka carbonic anhydrase 2 s homeolog)
D: caxiii (homo sapiens) (aka carbonic anhydrase 13)
E: caiii (homo sapiens) (aka carbonic anhydrase 3)
F: None of the above. | A |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca iii'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 3 (bos taurus) (aka carbonic anhydrase 3)
B: carbonic anhydrase 3 (homo sapiens) (aka carbonic anhydrase 3)
C: carbonic anhydrase iii (xenopus tropicalis) (aka carbonic anhydrase iii)
D: ac-iii (homo sapiens) (aka adenylate cyclase 3)
E: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
F: None of the above. | B |
<Instruct>: Given the context 'The exon-intron boundaries are found in positions identical to those determined for the previously described CA II, CA III, and CA VII genes.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: ca-vii (homo sapiens) (aka carbonic anhydrase 7)
B: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
C: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
D: carbonic anhydrase vii s homeolog (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
E: ca7 (gallus gallus) (aka carbonic anhydrase 7)
F: None of the above. | A |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
B: ca7 (gallus gallus) (aka carbonic anhydrase 7)
C: carbonic anhydrase 7 (homo sapiens) (aka carbonic anhydrase 7)
D: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
E: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
F: None of the above. | C |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca vii'. Answer using one of the provided options. | <Options>: A: ca-viii (homo sapiens) (aka carbonic anhydrase 8)
B: carbonic anhydrase vii (xenopus tropicalis) (aka carbonic anhydrase vii)
C: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
D: ca7 (gallus gallus) (aka carbonic anhydrase 7)
E: ca7.s (xenopus laevis) (aka carbonic anhydrase vii s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Like the CA VII gene, CA5 does not contain typical TATA and CAAT promoter elements in the 5' flanking region but does contain a TTTAA sequence 147 nucleotides upstream of the initiation codon.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5b (homo sapiens) (aka carbonic anhydrase 5b)
B: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
C: ca7.5 (mus musculus) (aka dna segment, ca7.5)
D: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
E: ca5d (homo sapiens) (aka carbonic anhydrase 5a)
F: None of the above. | E |
<Instruct>: Given the context 'CA5 also contains a 12-bp GT-rich segment beginning 13 bp downstream of the polyadenylation signal in the 3' untranslated region of exon 7.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: ca5p (homo sapiens) (aka carbonic anhydrase 5a pseudogene 1)
B: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
C: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
D: ca5d (homo sapiens) (aka carbonic anhydrase 5a)
E: ca7.5 (mus musculus) (aka dna segment, ca7.5)
F: None of the above. | D |
<Instruct>: Given the context 'FISH analysis allowed CA5 to be assigned to chromosome 16q24.3.', select the correct biomedical concept corresponding to 'ca5'. Answer using one of the provided options. | <Options>: A: carbonic anhydrase 5a (homo sapiens) (aka carbonic anhydrase 5a)
B: ca5b (homo sapiens) (aka carbonic anhydrase 5b)
C: putative carbonic anhydrase 5 (caenorhabditis elegans) (aka putative carbonic anhydrase 5)
D: ca7.5 (mus musculus) (aka dna segment, ca7.5)
E: ca-vi (homo sapiens) (aka carbonic anhydrase 6)
F: None of the above. | A |
<Instruct>: Given the context 'Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21.
', select the correct biomedical concept corresponding to 'brca1'. Answer using one of the provided options. | <Options>: A: pseudo-brca1 (homo sapiens) (aka brca1 pseudogene 1)
B: brca1 promoter region (homo sapiens) (aka brca1 promoter region)
C: brcaa1 (homo sapiens) (aka at-rich interaction domain 4b)
D: brca1 associated protein (homo sapiens) (aka brca1 associated protein)
E: brca1 (homo sapiens) (aka brca1 dna repair associated)
F: None of the above. | E |
<Instruct>: Given the context 'Fragments corresponding to the broadly expressed gamma-tubulin and Ki antigen genes were identified.', select the correct biomedical concept corresponding to 'ki antigen'. Answer using one of the provided options. | <Options>: A: marker of proliferation ki-67 (bos taurus) (aka marker of proliferation ki-67)
B: ki-1 (homo sapiens) (aka tnf receptor superfamily member 8)
C: marker of proliferation ki-67 (xenopus tropicalis) (aka marker of proliferation ki-67)
D: ki (homo sapiens) (aka proteasome activator subunit 3)
E: antigen identified by monoclonal antibody ki 67 (mus musculus) (aka antigen identified by monoclonal antibody ki 67)
F: None of the above. | D |
<Instruct>: Given the context 'A full-length cDNA clone encoding a 117-amino-acid protein homologous to the rat ribosomal protein L34 was isolated.', select the correct biomedical concept corresponding to 'ribosomal protein l34'. Answer using one of the provided options. | <Options>: A: ribosomal protein l34 (mus musculus) (aka ribosomal protein l34)
B: ribosomal protein l34 (bos taurus) (aka ribosomal protein l34)
C: l34 (xenopus laevis) (ribosomal protein l34 l homeolog (xenopus laevis)) (aka ribosomal protein l34 l homeolog)
D: ribosomal protein l34 (xenopus tropicalis) (aka ribosomal protein l34)
E: ribosomal protein l24 (homo sapiens) (aka ribosomal protein l24)
F: None of the above. | F |
<Instruct>: Given the context 'Portions of genes with restricted patterns of expression were also obtained, including the previously characterized HSD17B1.', select the correct biomedical concept corresponding to 'hsd17b1'. Answer using one of the provided options. | <Options>: A: hsd11b1 (homo sapiens) (aka hydroxysteroid 11-beta dehydrogenase 1)
B: hsd17b2 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 2)
C: hydroxysteroid 17-beta dehydrogenase 1 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 1)
D: hsd17b1 promoter (homo sapiens) (aka hsd17b1 promoter)
E: hsd17b3 (homo sapiens) (aka hydroxysteroid 17-beta dehydrogenase 3)
F: None of the above. | C |
<Instruct>: Given the context 'A novel K+ channel beta-subunit (hKv beta 1.3) is produced via alternative mRNA splicing.
', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
C: hkvbeta3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
D: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
E: None of the above. | C |
<Instruct>: Given the context 'We report here a novel K+ channel beta-subunit cloned from human heart, hKv beta 1.3, that has 74-83% overall identity with previously cloned beta-subunits.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
B: hkvbeta3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
C: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
D: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
E: None of the above. | B |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: None of the above. | D |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: hkvbeta2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
B: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: None of the above. | D |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'hkv beta 3'. Answer using one of the provided options. | <Options>: A: hkvbeta2.2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
B: kv-beta-3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 3)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: k(vca)beta-3 (homo sapiens) (aka potassium calcium-activated channel subfamily m regulatory beta subunit 3)
E: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
F: None of the above. | C |
<Instruct>: Given the context 'Comparison of hKv beta 1.3 with the previously cloned hKv beta 3 and rKv beta 1 proteins indicates that the carboxyl-terminal 328 amino acids are identical, while unique variable length amino termini exist.', select the correct biomedical concept corresponding to 'rkv beta 1'. Answer using one of the provided options. | <Options>: A: potassium voltage-gated channel subfamily a regulatory beta subunit 1 (rattus norvegicus) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)) (rattus norvegicus) (aka similar to rt1 class ii histocompatibility antigen, b-1 beta chain precursor (rt1.b-beta(1)))
C: rvb1 (homo sapiens) (aka ruvb like aaa atpase 1)
D: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
E: potassium channel, voltage gated subfamily a regulatory beta subunit 1 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
F: None of the above. | A |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
C: hkvbeta2.1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
D: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
E: None of the above. | B |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv1.5'. Answer using one of the provided options. | <Options>: A: task-5 (homo sapiens) (aka potassium two pore domain channel subfamily k member 15)
B: potassium voltage-gated channel subfamily a member 5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
C: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
D: potassium channel, subfamily v, member 1 (mus musculus) (aka potassium channel, subfamily v, member 1)
E: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
F: None of the above. | B |
<Instruct>: Given the context 'Co-expression of hKv beta 1.3 in Xenopus oocytes with the delayed rectifier hKv1.5 indicated that hKv beta 1.3 has unique functional effects.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvb1.3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
B: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
C: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
D: kv-beta-2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: None of the above. | A |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept corresponding to 'hkv beta 1.3'. Answer using one of the provided options. | <Options>: A: kvbeta1.3 (xenopus tropicalis) (aka potassium channel, voltage gated subfamily a regulatory beta subunit 1)
B: kv-beta-1 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 1)
C: kv-beta-3 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 3)
D: kv-beta-2 (homo sapiens) (aka potassium voltage-gated channel subfamily a regulatory beta subunit 2)
E: None of the above. | B |
<Instruct>: Given the context 'Most notably, hKv beta 1.3 converted the Kv1.5 outwardly rectifying current voltage relationship to one showing strong inward rectification.', select the correct biomedical concept corresponding to 'kv1.5'. Answer using one of the provided options. | <Options>: A: k(v)1.5 (xenopus laevis) (potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog (xenopus laevis)) (aka potassium channel, voltage gated shaker related subfamily a, member 5 l homeolog)
B: potassium voltage-gated channel subfamily a member 5 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 5)
C: kv7.5 (homo sapiens) (aka potassium voltage-gated channel subfamily q member 5)
D: kcnh5 (homo sapiens) (aka potassium voltage-gated channel subfamily h member 5)
E: task-5 (homo sapiens) (aka potassium two pore domain channel subfamily k member 15)
F: None of the above. | B |
<Instruct>: Given the context 'De novo mutation of the myelin P0 gene in Dejerine-Sottas disease (hereditary motor and sensory neuropathy type III).
', select the correct biomedical concept corresponding to 'myelin p0'. Answer using one of the provided options. | <Options>: A: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
B: myelin protein zero-like 1 (rattus norvegicus) (aka myelin protein zero-like 1)
C: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
D: ribosomal protein lateral stalk subunit p0 (mus musculus) (aka ribosomal protein lateral stalk subunit p0)
E: myelin protein zero (rattus norvegicus) (aka myelin protein zero)
F: None of the above. | A |
<Instruct>: Given the context 'We have investigated the myelin P0 gene on chromosome 1 as a candidate gene in two sporadic cases with Dejerine-Sottas disease or hereditary motor and sensory neuropathy (HMSN) type III.', select the correct biomedical concept corresponding to 'myelin p0'. Answer using one of the provided options. | <Options>: A: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
B: p0 (rattus norvegicus) (aka myelin protein zero)
C: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
D: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
E: ribosomal protein lateral stalk subunit p0 (mus musculus) (aka ribosomal protein lateral stalk subunit p0)
F: None of the above. | D |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept corresponding to 'p0'. Answer using one of the provided options. | <Options>: A: p0 (mus musculus) (aka myelin protein zero)
B: prlp0 (xenopus laevis) (ribosomal protein, large, p0 s homeolog (xenopus laevis)) (aka ribosomal protein, large, p0 s homeolog)
C: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
D: ribosomal protein lateral stalk subunit p0 (homo sapiens) (aka ribosomal protein lateral stalk subunit p0)
E: p0 (homo sapiens) (myelin protein zero (homo sapiens)) (aka myelin protein zero)
F: None of the above. | E |
<Instruct>: Given the context 'The results strongly suggest that a de novo dominant mutation of the P0 gene is responsible for at least some sporadic cases of Dejerine-Sottas disease.', select the correct biomedical concept corresponding to 'p0'. Answer using one of the provided options. | <Options>: A: ribosomal protein lateral stalk subunit p0 (rattus norvegicus) (aka ribosomal protein lateral stalk subunit p0)
B: p0 (mus musculus) (aka myelin protein zero)
C: lp0 (xenopus laevis) (ribosomal protein, large, p0 s homeolog (xenopus laevis)) (aka ribosomal protein, large, p0 s homeolog)
D: p0 (rattus norvegicus) (aka myelin protein zero)
E: p0 (drosophila melanogaster) (aka ribosomal protein lp0)
F: None of the above. | F |
<Instruct>: Given the context 'Human serum biotinidase.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (gallus gallus) (aka biotinidase)
B: biotinidase (sus scrofa) (aka biotinidase)
C: biotinidase (homo sapiens) (aka biotinidase)
D: biotinidase (oryctolagus cuniculus) (aka biotinidase)
E: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'cDNA cloning, sequence, and characterization.
Biotinidase (EC 3.5.1.12) catalyzes the hydrolysis of biocytin, the product of biotin-dependent carboxylase degradation, to biotin and lysine.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (mus musculus) (aka biotinidase)
B: biotinidase (homo sapiens) (aka biotinidase)
C: biotinidase (oryctolagus cuniculus) (aka biotinidase)
D: biotinidase (xenopus tropicalis) (aka biotinidase)
E: biotinidase (rattus norvegicus) (aka biotinidase)
F: None of the above. | B |
<Instruct>: Given the context 'Biotinidase deficiency is an inherited metabolic disorder of biotin recycling that is characterized by neurological and cutaneous abnormalities, and can be successfully treated with biotin supplementation.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
C: biotinidase (homo sapiens) (aka biotinidase)
D: biotinidase (rattus norvegicus) (aka biotinidase)
E: biotinidase (gallus gallus) (aka biotinidase)
F: None of the above. | C |
<Instruct>: Given the context 'Sequences of tryptic peptides of the purified human serum enzyme were used to design oligonucleotide primers for polymerase chain reaction amplification from human hepatic total RNA to generate putative biotinidase cDNA fragments.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (oryctolagus cuniculus) (aka biotinidase)
B: biotinidase (sus scrofa) (aka biotinidase)
C: biotinidase (homo sapiens) (aka biotinidase)
D: biotinidase (mus musculus) (aka biotinidase)
E: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (gallus gallus) (aka biotinidase)
B: biotinase (bos taurus) (aka biotinidase)
C: biotinidase (homo sapiens) (aka biotinidase)
D: biotinidase (rattus norvegicus) (aka biotinidase)
E: biotinidase (oryctolagus cuniculus) (aka biotinidase)
F: None of the above. | C |
<Instruct>: Given the context 'Comparison of the open reading frame with the known biotinidase tryptic peptides and recognition of the expressed protein encoded by this cDNA by monoclonal antibodies prepared against purified biotinidase demonstrated the identity of this cDNA.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (oryctolagus cuniculus) (aka biotinidase)
B: biotinidase (xenopus tropicalis) (aka biotinidase)
C: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
D: biotinidase (sus scrofa) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | E |
<Instruct>: Given the context 'Southern analyses suggested that biotinidase is a single copy gene and revealed that human cDNA probes hybridized to genomic DNA from mammals, but not from chicken or yeast.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinidase (sus scrofa) (aka biotinidase)
B: biotinidase (homo sapiens) (aka biotinidase)
C: biotinidase (gallus gallus) (aka biotinidase)
D: biotinidase (xenopus tropicalis) (aka biotinidase)
E: biotinidase (mus musculus) (aka biotinidase)
F: None of the above. | B |
<Instruct>: Given the context 'Northern analysis indicated the presence of biotinidase mRNA in human heart, brain, placenta, liver, lung, skeletal muscle, kidney, and pancreas.', select the correct biomedical concept corresponding to 'biotinidase'. Answer using one of the provided options. | <Options>: A: biotinase (bos taurus) (aka biotinidase)
B: biotinidase (xenopus laevis) (aka biotinidase l homeolog)
C: biotinidase (xenopus tropicalis) (aka biotinidase)
D: biotinidase (mus musculus) (aka biotinidase)
E: biotinidase (homo sapiens) (aka biotinidase)
F: None of the above. | E |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'c3g'. Answer using one of the provided options. | <Options>: A: complement c8 gamma chain (homo sapiens) (aka complement c8 gamma chain)
B: c3g (homo sapiens) (aka rap guanine nucleotide exchange factor 1)
C: c3g (mus musculus) (aka rap guanine nucleotide exchange factor (gef) 1)
D: c1qg (homo sapiens) (aka complement c1q c chain)
E: c3g (drosophila melanogaster) (crossover suppressor on 3 of gowen (drosophila melanogaster)) (aka crossover suppressor on 3 of gowen)
F: None of the above. | B |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
B: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
C: crk (drosophila melanogaster) (crk oncogene (drosophila melanogaster)) (aka crk oncogene)
D: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
E: crkii (homo sapiens) (aka crk proto-oncogene, adaptor protein)
F: None of the above. | E |
<Instruct>: Given the context 'C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins.
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases.', select the correct biomedical concept corresponding to 'crk'. Answer using one of the provided options. | <Options>: A: crk7 (homo sapiens) (aka cyclin dependent kinase 12)
B: crkii (xenopus laevis) (v-crk avian sarcoma virus ct10 oncogene homolog s homeolog (xenopus laevis)) (aka v-crk avian sarcoma virus ct10 oncogene homolog s homeolog)
C: crk (gallus gallus) (aka crk proto-oncogene, adaptor protein)
D: v-crk avian sarcoma virus ct10 oncogene homolog (xenopus tropicalis) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
E: v-crk avian sarcoma virus ct10 oncogene homolog (mus musculus) (aka v-crk avian sarcoma virus ct10 oncogene homolog)
F: None of the above. | F |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.