instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'The rank order of CB2 mRNA levels in these cells was B-cells > natural killer cells >> monocytes > polymorphonuclear neutrophil cells > T8 cells > T4 cells.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: gababr2 (homo sapiens) (aka gamma-aminobutyric acid type b receptor subunit 2)
B: ckr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
D: corticotropin releasing hormone receptor 2 (homo sapiens) (aka corticotropin releasing hormone receptor 2)
E: cannabinoid receptor 2 (homo sapiens) (aka cannabinoid receptor 2)
F: None of the above. | E |
<Instruct>: Given the context 'The prevailing expression of the CB2 gene in immune tissues was confirmed by Northern-blot analysis.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: corticotropin releasing hormone receptor 2 (homo sapiens) (aka corticotropin releasing hormone receptor 2)
B: cb2 (homo sapiens) (aka cannabinoid receptor 2)
C: neuropeptides b and w receptor 2 (homo sapiens) (aka neuropeptides b and w receptor 2)
D: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
E: gprchr2 (homo sapiens) (aka g protein-coupled receptor 75)
F: None of the above. | B |
<Instruct>: Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: gababr2 (homo sapiens) (aka gamma-aminobutyric acid type b receptor subunit 2)
B: cannabinoid receptor 2 (homo sapiens) (aka cannabinoid receptor 2)
C: corticotropin releasing hormone receptor 2 (homo sapiens) (aka corticotropin releasing hormone receptor 2)
D: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
E: gprchr2 (homo sapiens) (aka g protein-coupled receptor 75)
F: None of the above. | B |
<Instruct>: Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: cannabinoid receptor 2 (homo sapiens) (aka cannabinoid receptor 2)
B: cc-ckr-2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: gababr2 (homo sapiens) (aka gamma-aminobutyric acid type b receptor subunit 2)
D: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
E: neuropeptides b and w receptor 2 (homo sapiens) (aka neuropeptides b and w receptor 2)
F: None of the above. | A |
<Instruct>: Given the context 'In addition, the expression of the CB2 protein was demonstrated by an immunohistological analysis performed on tonsil sections using specific anti-(human CB2) IgG; this experiment showed that CB2 expression was restricted to B-lymphocyte-enriched areas of the mantle of secondary lymphoid follicles.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: cb2 (homo sapiens) (aka cannabinoid receptor 2)
B: neuropeptides b and w receptor 2 (homo sapiens) (aka neuropeptides b and w receptor 2)
C: cc-ckr-2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
E: gprchr2 (homo sapiens) (aka g protein-coupled receptor 75)
F: None of the above. | A |
<Instruct>: Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', select the correct biomedical concept corresponding to 'cb1'. Answer using one of the provided options. | <Options>: A: cb1a (mus musculus) (aka cannabinoid receptor 1)
B: cannabinoid receptor 1 (homo sapiens) (aka cannabinoid receptor 1)
C: cannabinoid receptor 1 (rattus norvegicus) (aka cannabinoid receptor 1)
D: None of the above. | B |
<Instruct>: Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
B: cannabinoid receptor 2 (homo sapiens) (aka cannabinoid receptor 2)
C: cmkbr2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: gababr2 (homo sapiens) (aka gamma-aminobutyric acid type b receptor subunit 2)
E: corticotropin releasing hormone receptor 2 (homo sapiens) (aka corticotropin releasing hormone receptor 2)
F: None of the above. | B |
<Instruct>: Given the context 'These results suggest that (a) CB1 and CB2 can be considered as tissue-selective antigens of the central nervous system and immune system, respectively, and (b) cannabinoids may exert specific receptor-mediated actions on the immune system through the CB2 receptor.', select the correct biomedical concept corresponding to 'cb2'. Answer using one of the provided options. | <Options>: A: gprc2b (homo sapiens) (aka vomeronasal 2 receptor 1 pseudogene)
B: cc-ckr-2 (homo sapiens) (aka c-c motif chemokine receptor 2)
C: gababr2 (homo sapiens) (aka gamma-aminobutyric acid type b receptor subunit 2)
D: cannabinoid receptor 2 (homo sapiens) (aka cannabinoid receptor 2)
E: gprchr2 (homo sapiens) (aka g protein-coupled receptor 75)
F: None of the above. | D |
<Instruct>: Given the context 'Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2.
', select the correct biomedical concept corresponding to 'proteinase-activated receptor 2'. Answer using one of the provided options. | <Options>: A: par-1b (homo sapiens) (aka microtubule affinity regulating kinase 2)
B: f2r like thrombin or trypsin receptor 3 (homo sapiens) (aka f2r like thrombin or trypsin receptor 3)
C: par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens)) (aka f2r like trypsin receptor 1)
D: f2r (homo sapiens) (aka coagulation factor ii thrombin receptor)
E: proteinase-activated receptor 2-like (gallus gallus) (aka proteinase-activated receptor 2-like)
F: None of the above. | C |
<Instruct>: Given the context 'Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2.
', select the correct biomedical concept corresponding to 'proteinase-activated receptor 2'. Answer using one of the provided options. | <Options>: A: proteinase-activated receptor 2-like (gallus gallus) (aka proteinase-activated receptor 2-like)
B: par-1b (homo sapiens) (aka microtubule affinity regulating kinase 2)
C: par3 (homo sapiens) (coagulation factor ii thrombin receptor like 2 (homo sapiens)) (aka coagulation factor ii thrombin receptor like 2)
D: f2r (homo sapiens) (aka coagulation factor ii thrombin receptor)
E: prokr2 (homo sapiens) (aka prokineticin receptor 2)
F: None of the above. | F |
<Instruct>: Given the context 'Since the physiological agonist was unknown, the receptor was named proteinase-activated receptor 2.', select the correct biomedical concept corresponding to 'proteinase-activated receptor 2'. Answer using one of the provided options. | <Options>: A: par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens)) (aka f2r like trypsin receptor 1)
B: f2r like thrombin or trypsin receptor 3 (homo sapiens) (aka f2r like thrombin or trypsin receptor 3)
C: f2r (homo sapiens) (aka coagulation factor ii thrombin receptor)
D: par-1b (homo sapiens) (aka microtubule affinity regulating kinase 2)
E: coagulation factor ii thrombin receptor like 2 (homo sapiens) (aka coagulation factor ii thrombin receptor like 2)
F: None of the above. | A |
<Instruct>: Given the context 'By fluorescence in situ hybridization, the human proteinase-activated receptor 2 gene was mapped to chromosomal region 5q13, where, previously, the related thrombin receptor gene has been located.', select the correct biomedical concept corresponding to 'proteinase-activated receptor 2'. Answer using one of the provided options. | <Options>: A: prokr2 (homo sapiens) (aka prokineticin receptor 2)
B: f2r (homo sapiens) (aka coagulation factor ii thrombin receptor)
C: par-1b (homo sapiens) (aka microtubule affinity regulating kinase 2)
D: par2 (homo sapiens) (f2r like trypsin receptor 1 (homo sapiens)) (aka f2r like trypsin receptor 1)
E: proteinase-activated receptor 2-like (gallus gallus) (aka proteinase-activated receptor 2-like)
F: None of the above. | D |
<Instruct>: Given the context 'We have described a protein (Hep27)', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: es27 (homo sapiens) (aka ribosomal protein s27)
B: ncc27 (homo sapiens) (aka chloride intracellular channel 1)
C: hel-s-27 (homo sapiens) (aka serpin family b member 1)
D: hep27 (mus musculus) (aka dehydrogenase/reductase member 2)
E: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
F: None of the above. | E |
<Instruct>: Given the context 'The synthesis of Hep27 is inhibited in cells that, released from the butyrate block, have resumed DNA synthesis.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hsf-27 (homo sapiens) (aka cdk5 regulatory subunit associated protein 3)
B: hep27 (mus musculus) (aka dehydrogenase/reductase member 2)
C: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
D: gp27 (homo sapiens) (aka cd151 molecule (raph blood group))
E: ncc27 (homo sapiens) (aka chloride intracellular channel 1)
F: None of the above. | C |
<Instruct>: Given the context 'This report describes the cloning and the characterization of the cDNA coding for the Hep27 protein.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hh27 (homo sapiens) (aka nescient helix-loop-helix 2)
B: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
C: lc27 (homo sapiens) (aka lysosomal protein transmembrane 4 beta)
D: hsf-27 (homo sapiens) (aka cdk5 regulatory subunit associated protein 3)
E: hcp27 (homo sapiens) (aka cycs pseudogene 27)
F: None of the above. | B |
<Instruct>: Given the context 'The translation of the Hep27 cDNA predicts an amino acid sequence that can be aligned with those of the known short-chain alcohol dehydrogenase enzymes (SCAD) family.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
B: ncc27 (homo sapiens) (aka chloride intracellular channel 1)
C: hel-s-27 (homo sapiens) (aka serpin family b member 1)
D: hh27 (homo sapiens) (aka nescient helix-loop-helix 2)
E: lc27 (homo sapiens) (aka lysosomal protein transmembrane 4 beta)
F: None of the above. | A |
<Instruct>: Given the context 'In agreement with its nuclear localization Hep27 has a region similar to the bipartite nuclear-targeting sequence.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hcp27 (homo sapiens) (aka cycs pseudogene 27)
B: hep27 (mus musculus) (aka dehydrogenase/reductase member 2)
C: hh27 (homo sapiens) (aka nescient helix-loop-helix 2)
D: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
E: gp27 (homo sapiens) (aka cd151 molecule (raph blood group))
F: None of the above. | D |
<Instruct>: Given the context 'The study of Hep27 mRNA expression and protein synthesis suggests the existence of a regulation at the post-transcriptional level.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
B: gp27 (homo sapiens) (aka cd151 molecule (raph blood group))
C: hep27 (mus musculus) (aka dehydrogenase/reductase member 2)
D: lc27 (homo sapiens) (aka lysosomal protein transmembrane 4 beta)
E: es27 (homo sapiens) (aka ribosomal protein s27)
F: None of the above. | A |
<Instruct>: Given the context 'The possible nuclear role of the Hep27 protein is discussed.', select the correct biomedical concept corresponding to 'hep27'. Answer using one of the provided options. | <Options>: A: hep27 (homo sapiens) (aka dehydrogenase/reductase 2)
B: hep27 (mus musculus) (aka dehydrogenase/reductase member 2)
C: ncc27 (homo sapiens) (aka chloride intracellular channel 1)
D: gp27 (homo sapiens) (aka cd151 molecule (raph blood group))
E: hcp27 (homo sapiens) (aka cycs pseudogene 27)
F: None of the above. | A |
<Instruct>: Given the context 'Human papillomaviruses (HPVs) are associated with the majority of cervical cancers and encode a transforming protein, E6, that interacts with the tumor suppressor protein p53.', select the correct biomedical concept corresponding to 'p53'. Answer using one of the provided options. | <Options>: A: tp53 (homo sapiens) (aka tumor protein p53)
B: p532 (homo sapiens) (aka hect and rld domain containing e3 ubiquitin protein ligase family member 1)
C: ct53 (homo sapiens) (aka zinc finger protein 165)
D: rad53 (homo sapiens) (aka checkpoint kinase 2)
E: tumor protein p73 (homo sapiens) (aka tumor protein p73)
F: None of the above. | A |
<Instruct>: Given the context 'Human papillomaviruses (HPVs) are associated with the majority of cervical cancers and encode a transforming protein, E6, that interacts with the tumor suppressor protein p53.', select the correct biomedical concept corresponding to 'p53'. Answer using one of the provided options. | <Options>: A: tp73 (homo sapiens) (aka tumor protein p73)
B: p53cp (homo sapiens) (aka tumor protein p63)
C: rad53 (homo sapiens) (aka checkpoint kinase 2)
D: p532 (homo sapiens) (aka hect and rld domain containing e3 ubiquitin protein ligase family member 1)
E: ct53 (homo sapiens) (aka zinc finger protein 165)
F: None of the above. | F |
<Instruct>: Given the context 'Because E6 has p53-independent transforming activity, the yeast two-hybrid system was used to search for other E6-binding proteins.', select the correct biomedical concept corresponding to 'p53'. Answer using one of the provided options. | <Options>: A: rad53 (homo sapiens) (aka checkpoint kinase 2)
B: p53cp (homo sapiens) (aka tumor protein p63)
C: tp53 (homo sapiens) (aka tumor protein p53)
D: p532 (homo sapiens) (aka hect and rld domain containing e3 ubiquitin protein ligase family member 1)
E: tp73 (homo sapiens) (aka tumor protein p73)
F: None of the above. | C |
<Instruct>: Given the context 'One such protein, E6BP, interacted with cancer-associated HPV E6 and with bovine papillomavirus type 1 (BPV-1) E6.', select the correct biomedical concept corresponding to 'e6bp'. Answer using one of the provided options. | <Options>: A: e6-ap (homo sapiens) (aka ubiquitin protein ligase e3a)
B: 16e1bp (homo sapiens) (aka thyroid hormone receptor interactor 13)
C: e5 (human papillomavirus 16) (aka transforming protein e5)
D: e6bp (homo sapiens) (aka reticulocalbin 2)
E: e3bp (homo sapiens) (aka pyruvate dehydrogenase complex component x)
F: None of the above. | D |
<Instruct>: Given the context 'The transforming activity of BPV-1 E6 mutants correlated with their E6BP-binding ability.', select the correct biomedical concept corresponding to 'e6bp'. Answer using one of the provided options. | <Options>: A: 16e1bp (homo sapiens) (aka thyroid hormone receptor interactor 13)
B: protein e6*;transforming protein e6 (human papillomavirus 16) (aka protein e6*;transforming protein e6)
C: e3bp (homo sapiens) (aka pyruvate dehydrogenase complex component x)
D: e6bp (homo sapiens) (aka reticulocalbin 2)
E: e5 (human papillomavirus 16) (aka transforming protein e5)
F: None of the above. | D |
<Instruct>: Given the context 'E6BP is identical to a putative calcium-binding protein, ERC-55, that appears to be localized in the endoplasmic reticulum.', select the correct biomedical concept corresponding to 'e6bp'. Answer using one of the provided options. | <Options>: A: ebbp (homo sapiens) (aka tripartite motif containing 16)
B: e6-ap (homo sapiens) (aka ubiquitin protein ligase e3a)
C: ubc6p (homo sapiens) (aka ubiquitin conjugating enzyme e2 j1)
D: 16e1bp (homo sapiens) (aka thyroid hormone receptor interactor 13)
E: e6bp (homo sapiens) (aka reticulocalbin 2)
F: None of the above. | E |
<Instruct>: Given the context 'E6BP is identical to a putative calcium-binding protein, ERC-55, that appears to be localized in the endoplasmic reticulum.', select the correct biomedical concept corresponding to 'erc-55'. Answer using one of the provided options. | <Options>: A: rad55 (saccharomyces cerevisiae s288c) (aka putative dna-dependent atpase rad55)
B: ct55 (homo sapiens) (aka cancer/testis antigen 55)
C: ercc5 (homo sapiens) (aka ercc excision repair 5, endonuclease)
D: testis expressed 55 (homo sapiens) (aka testis expressed 55)
E: erc-55 (homo sapiens) (aka reticulocalbin 2)
F: None of the above. | E |
<Instruct>: Given the context 'A phosphoinositide-3 kinase isotype, p110 gamma, was cloned and characterized.', select the correct biomedical concept corresponding to 'p110 gamma'. Answer using one of the provided options. | <Options>: A: p110-alpha (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha)
B: p110beta (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta)
C: pi3kgamma (mus musculus) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
D: pi3kgamma (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
E: pi3k-c2-gamma (homo sapiens) (aka phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)
F: None of the above. | D |
<Instruct>: Given the context 'The p110 gamma enzyme was activated in vitro by both the alpha and beta gamma subunits of heterotrimeric guanosine triphosphate (GTP)-binding proteins (G proteins) and did not interact with p85.', select the correct biomedical concept corresponding to 'p110 gamma'. Answer using one of the provided options. | <Options>: A: p110gamma (mus musculus) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
B: p110-alpha (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha)
C: p110beta (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta)
D: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
E: pi3k-c2-gamma (homo sapiens) (aka phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)
F: None of the above. | D |
<Instruct>: Given the context 'The p110 gamma isotype may link signaling through G protein-coupled receptors to the generation of phosphoinositide second messengers phosphorylated in the D-3 position.', select the correct biomedical concept corresponding to 'p110 gamma'. Answer using one of the provided options. | <Options>: A: p110beta (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta)
B: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
C: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma (homo sapiens) (aka phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma)
D: p110-alpha (homo sapiens) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha)
E: p110gamma (mus musculus) (aka phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma)
F: None of the above. | B |
<Instruct>: Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', select the correct biomedical concept corresponding to 'znf133'. Answer using one of the provided options. | <Options>: A: rnf133 (homo sapiens) (aka ring finger protein 133)
B: zinc finger protein 132 (homo sapiens) (aka zinc finger protein 132)
C: znf133 (homo sapiens) (aka zinc finger protein 133)
D: bzip133 (glycine max) (aka putative bzip domain class transcription factor)
E: zinc finger protein 136 (homo sapiens) (aka zinc finger protein 136)
F: None of the above. | C |
<Instruct>: Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', select the correct biomedical concept corresponding to 'znf140'. Answer using one of the provided options. | <Options>: A: znf404 (homo sapiens) (aka zinc finger protein 404)
B: znf139 (homo sapiens) (aka zinc finger with krab and scan domains 1)
C: rnf140 (homo sapiens) (aka deltex e3 ubiquitin ligase 1)
D: znf140 (homo sapiens) (aka zinc finger protein 140)
E: znf140l (homo sapiens) (aka zinc finger protein 302)
F: None of the above. | D |
<Instruct>: Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', select the correct biomedical concept corresponding to 'znf140'. Answer using one of the provided options. | <Options>: A: znf404 (homo sapiens) (aka zinc finger protein 404)
B: znf400 (homo sapiens) (aka zdhhc palmitoyltransferase 12)
C: rnf140 (homo sapiens) (aka deltex e3 ubiquitin ligase 1)
D: znf40a (homo sapiens) (aka hivep zinc finger 1)
E: znf140l (homo sapiens) (aka zinc finger protein 302)
F: None of the above. | F |
<Instruct>: Given the context 'ZNF133 and ZNF140 have both the KRAB A- and KRAB B-boxes present at their N-terminus, whereas ZNF136 contains only the KRAB A-box.', select the correct biomedical concept corresponding to 'znf136'. Answer using one of the provided options. | <Options>: A: zinc finger protein 135 (homo sapiens) (aka zinc finger protein 135)
B: cg13612 (drosophila melanogaster) (uncharacterized protein (drosophila melanogaster)) (aka uncharacterized protein)
C: zinc finger protein 136 (homo sapiens) (aka zinc finger protein 136)
D: fam161 homolog famh-136 (caenorhabditis elegans) (aka fam161 homolog famh-136)
E: zinc finger protein 236 (homo sapiens) (aka zinc finger protein 236)
F: None of the above. | C |
<Instruct>: Given the context 'We have previously demonstrated that the KRAB domains derived from ZNF133 and ZNF140 are potent transcriptional repression domains', select the correct biomedical concept corresponding to 'znf133'. Answer using one of the provided options. | <Options>: A: zinc finger protein 132 (homo sapiens) (aka zinc finger protein 132)
B: znf133 (homo sapiens) (aka zinc finger protein 133)
C: bzip133 (glycine max) (aka putative bzip domain class transcription factor)
D: zinc finger protein 195 (homo sapiens) (aka zinc finger protein 195)
E: zinc finger protein 136 (homo sapiens) (aka zinc finger protein 136)
F: None of the above. | B |
<Instruct>: Given the context 'We have previously demonstrated that the KRAB domains derived from ZNF133 and ZNF140 are potent transcriptional repression domains', select the correct biomedical concept corresponding to 'znf140'. Answer using one of the provided options. | <Options>: A: zinc finger protein 140 (homo sapiens) (aka zinc finger protein 140)
B: znf139 (homo sapiens) (aka zinc finger with krab and scan domains 1)
C: znf404 (homo sapiens) (aka zinc finger protein 404)
D: znf40a (homo sapiens) (aka hivep zinc finger 1)
E: znf400 (homo sapiens) (aka zdhhc palmitoyltransferase 12)
F: None of the above. | A |
<Instruct>: Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', select the correct biomedical concept corresponding to 'znf136'. Answer using one of the provided options. | <Options>: A: chromosome 8 c6orf136 homolog (xenopus tropicalis) (aka chromosome 8 c6orf136 homolog)
B: zinc finger protein 236 (homo sapiens) (aka zinc finger protein 236)
C: ct136 (homo sapiens) (aka outer dense fiber of sperm tails 4)
D: znf136 (homo sapiens) (aka zinc finger protein 136)
E: lethal (1) ts136 (drosophila melanogaster) (aka lethal (1) ts136)
F: None of the above. | D |
<Instruct>: Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', select the correct biomedical concept corresponding to 'znf10'. Answer using one of the provided options. | <Options>: A: znf10 (homo sapiens) (aka zinc finger protein 10)
B: zinc finger protein 10-like (glycine max) (aka zinc finger protein 10-like)
C: kox10 (homo sapiens) (aka zinc finger protein 17)
D: zinc finger and btb domain containing 10 (homo sapiens) (aka zinc finger and btb domain containing 10)
E: znf210 (homo sapiens) (aka zinc finger protein 205)
F: None of the above. | A |
<Instruct>: Given the context 'The KRAB domain from ZNF136, containing only subdomain A, is a considerable weaker suppression domain; however, when fused to the heterologous KRAB B subdomain of ZNF10 (KOX1) the two subdomains from a KRAB domain which induces repression as potently as previously reported KRAB domains.', select the correct biomedical concept corresponding to 'kox1'. Answer using one of the provided options. | <Options>: A: kox8 (homo sapiens) (aka zinc finger protein 708)
B: kox7 (homo sapiens) (aka zinc finger protein 44)
C: kox6 (homo sapiens) (aka zinc finger protein 14)
D: kox1 (homo sapiens) (aka zinc finger protein 10)
E: kox3 (homo sapiens) (aka zinc finger protein 12)
F: None of the above. | D |
<Instruct>: Given the context 'One form of hereditary long QT (LQT3) has been linked to a mutation in the gene encoding the human heart voltage-gated sodium-channel alpha-subunit (SCN5A on chromosome 3p21).', select the correct biomedical concept corresponding to 'heart voltage-gated sodium-channel alpha-subunit'. Answer using one of the provided options. | <Options>: A: scn5a (homo sapiens) (sodium voltage-gated channel alpha subunit 5 (homo sapiens)) (aka sodium voltage-gated channel alpha subunit 5)
B: nav1.1 (homo sapiens) (aka sodium voltage-gated channel alpha subunit 1)
C: scnn1a (homo sapiens) (aka sodium channel epithelial 1 subunit alpha)
D: None of the above. | A |
<Instruct>: Given the context 'One form of hereditary long QT (LQT3) has been linked to a mutation in the gene encoding the human heart voltage-gated sodium-channel alpha-subunit (SCN5A on chromosome 3p21).', select the correct biomedical concept corresponding to 'scn5a'. Answer using one of the provided options. | <Options>: A: scn5a (sus scrofa) (aka sodium voltage-gated channel alpha subunit 5)
B: scnn1a (homo sapiens) (aka sodium channel epithelial 1 subunit alpha)
C: scn1a (homo sapiens) (aka sodium voltage-gated channel alpha subunit 1)
D: scn5a (rattus norvegicus) (aka sodium voltage-gated channel alpha subunit 5)
E: nav1.5 (homo sapiens) (aka sodium voltage-gated channel alpha subunit 5)
F: None of the above. | E |
<Instruct>: Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', select the correct biomedical concept corresponding to 'eif-4f'. Answer using one of the provided options. | <Options>: A: eukaryotic translation initiation factor 4h (homo sapiens) (aka eukaryotic translation initiation factor 4h)
B: eif4f (drosophila melanogaster) (eukaryotic translation initiation factor 4e4 (drosophila melanogaster)) (aka eukaryotic translation initiation factor 4e4)
C: eukaryotic translation initiation factor 4e-4 (caenorhabditis elegans) (aka eukaryotic translation initiation factor 4e-4)
D: eif-4e (homo sapiens) (aka eukaryotic translation initiation factor 4e)
E: eukaryotic translation initiation factor 4b (homo sapiens) (aka eukaryotic translation initiation factor 4b)
F: None of the above. | D |
<Instruct>: Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', select the correct biomedical concept corresponding to 'cbp80'. Answer using one of the provided options. | <Options>: A: cbp80 (arabidopsis thaliana) (aka arm repeat superfamily protein)
B: cbp86 (homo sapiens) (aka calcium binding tyrosine phosphorylation regulated)
C: cbp80 (homo sapiens) (aka nuclear cap binding protein subunit 1)
D: cbp80 (drosophila melanogaster) (aka cap binding protein 80)
E: fact80 (homo sapiens) (aka structure specific recognition protein 1)
F: None of the above. | C |
<Instruct>: Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', select the correct biomedical concept corresponding to 'cbp80'. Answer using one of the provided options. | <Options>: A: cbp86 (homo sapiens) (aka calcium binding tyrosine phosphorylation regulated)
B: cbp68 (homo sapiens) (aka annexin a6)
C: cbp80 (saccharomyces cerevisiae s288c) (aka sto1p)
D: cbp80 (mus musculus) (aka nuclear cap binding protein subunit 1)
E: fact80 (homo sapiens) (aka structure specific recognition protein 1)
F: None of the above. | F |
<Instruct>: Given the context 'The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex (CBC) composed of two cap binding proteins, CBP80 and CBP20.', select the correct biomedical concept corresponding to 'cbp20'. Answer using one of the provided options. | <Options>: A: cbp20 (xenopus tropicalis) (aka nuclear cap binding protein subunit 2)
B: cap binding protein 20 (drosophila melanogaster) (aka cap binding protein 20)
C: cbp20 (homo sapiens) (aka nuclear cap binding protein subunit 2)
D: small subunit processome component 20 homolog (xenopus laevis) (aka small subunit processome component 20 homolog)
E: small subunit processome component 20 homolog (glycine max) (aka small subunit processome component 20 homolog)
F: None of the above. | C |
<Instruct>: Given the context 'Antibodies against recombinant CBP20 prevent interaction of CBC with capped RNAs in vitro.', select the correct biomedical concept corresponding to 'cbp20'. Answer using one of the provided options. | <Options>: A: small subunit processome component 20 homolog (xenopus laevis) (aka small subunit processome component 20 homolog)
B: cbp20 (homo sapiens) (aka nuclear cap binding protein subunit 2)
C: cbp20 (saccharomyces cerevisiae s288c) (aka nuclear cap-binding protein subunit cbc2)
D: small subunit processome component 20 homolog (glycine max) (aka small subunit processome component 20 homolog)
E: cbp20 (drosophila melanogaster) (aka cap binding protein 20)
F: None of the above. | B |
<Instruct>: Given the context 'Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
', select the correct biomedical concept corresponding to 'carboxypeptidase e'. Answer using one of the provided options. | <Options>: A: carboxypeptidase e (caenorhabditis elegans) (aka carboxypeptidase e)
B: carboxypeptidase e (mus musculus) (aka carboxypeptidase e)
C: carboxypeptidase e (rattus norvegicus) (aka carboxypeptidase e)
D: carboxypeptidase e (gallus gallus) (aka carboxypeptidase e)
E: carboxypeptidase e (xenopus tropicalis) (aka carboxypeptidase e)
F: None of the above. | B |
<Instruct>: Given the context 'The fat mutation maps to mouse chromosome 8, very close to the gene for carboxypeptidase E (Cpe), which encodes an enzyme (CPE) that processes prohormone intermediates such as proinsulin.', select the correct biomedical concept corresponding to 'carboxypeptidase e'. Answer using one of the provided options. | <Options>: A: carboxypeptidase e (rattus norvegicus) (aka carboxypeptidase e)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: carboxypeptidase e (gallus gallus) (aka carboxypeptidase e)
D: carboxypeptidase e (mus musculus) (aka carboxypeptidase e)
E: carboxypeptidase e (bos taurus) (aka carboxypeptidase e)
F: None of the above. | D |
<Instruct>: Given the context 'The fat mutation maps to mouse chromosome 8, very close to the gene for carboxypeptidase E (Cpe), which encodes an enzyme (CPE) that processes prohormone intermediates such as proinsulin.', select the correct biomedical concept corresponding to 'cpe'. Answer using one of the provided options. | <Options>: A: cpe1 (homo sapiens) (aka cytochrome p450 family 2 subfamily e member 1)
B: cpea (escherichia coli str. k-12 substr. mg1655) (aka exodeoxyribonuclease i)
C: cpeb (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
D: cpepe (drosophila melanogaster) (aka silver)
E: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
F: None of the above. | F |
<Instruct>: Given the context 'The fat mutation maps to mouse chromosome 8, very close to the gene for carboxypeptidase E (Cpe), which encodes an enzyme (CPE) that processes prohormone intermediates such as proinsulin.', select the correct biomedical concept corresponding to 'cpe'. Answer using one of the provided options. | <Options>: A: cpea (escherichia coli str. k-12 substr. mg1655) (aka exodeoxyribonuclease i)
B: cpe1 (homo sapiens) (aka cytochrome p450 family 2 subfamily e member 1)
C: cpe (gallus gallus) (aka carboxypeptidase e)
D: cpeb (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
E: cpepe (drosophila melanogaster) (aka silver)
F: None of the above. | F |
<Instruct>: Given the context 'We now demonstrate a defect in proinsulin processing associated with the virtual absence of CPE activity in extracts of fat/fat pancreatic islets and pituitaries.', select the correct biomedical concept corresponding to 'cpe'. Answer using one of the provided options. | <Options>: A: cpe1 (homo sapiens) (aka cytochrome p450 family 2 subfamily e member 1)
B: carboxypeptidase e (homo sapiens) (aka carboxypeptidase e)
C: cpeb (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
D: cpea (escherichia coli str. k-12 substr. mg1655) (aka exodeoxyribonuclease i)
E: cper (homo sapiens) (aka claudin 4)
F: None of the above. | F |
<Instruct>: Given the context 'A single Ser202Pro mutation distinguishes the mutant Cpe allele, and abolishes enzymatic activity in vitro.', select the correct biomedical concept corresponding to 'cpe'. Answer using one of the provided options. | <Options>: A: cpeb (homo sapiens) (aka cytoplasmic polyadenylation element binding protein 1)
B: cpe (gallus gallus) (aka carboxypeptidase e)
C: cpe (homo sapiens) (aka carboxypeptidase e)
D: cpepe (drosophila melanogaster) (aka silver)
E: carboxypeptidase e (oryctolagus cuniculus) (cpe (oryctolagus cuniculus)) (aka carboxypeptidase e)
F: None of the above. | F |
<Instruct>: Given the context 'A novel gene, Translin, encodes a recombination hotspot binding protein associated with chromosomal translocations.
', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (xenopus tropicalis) (aka translin)
B: translin-like (xenopus tropicalis) (aka translin-like)
C: translin-like (bos taurus) (aka translin-like)
D: translin (homo sapiens) (aka translin)
E: translin (drosophila melanogaster) (aka translin)
F: None of the above. | D |
<Instruct>: Given the context 'We have identified a novel gene, Translin, encoding a protein which specifically binds to consensus sequences at breakpoint junctions of chromosomal translocations in many cases of lymphoid malignancies.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (sus scrofa) (aka translin)
B: translin-like (bos taurus) (aka translin-like)
C: translin (homo sapiens) (aka translin)
D: translin (bos taurus) (aka translin)
E: translin (xenopus tropicalis) (aka translin)
F: None of the above. | C |
<Instruct>: Given the context 'We have identified a novel gene, Translin, encoding a protein which specifically binds to consensus sequences at breakpoint junctions of chromosomal translocations in many cases of lymphoid malignancies.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (sus scrofa) (aka translin)
B: translin (xenopus tropicalis) (aka translin)
C: translin (drosophila melanogaster) (aka translin)
D: translin (glycine max) (aka translin)
E: translin (mus musculus) (aka translin)
F: None of the above. | F |
<Instruct>: Given the context 'The encoded protein, Translin, is a previously undescribed type with no significant similarity to known proteins.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (mus musculus) (aka translin)
B: translin-like (bos taurus) (aka translin-like)
C: translin (homo sapiens) (aka translin)
D: translin (glycine max) (aka translin)
E: translin (danio rerio) (aka translin)
F: None of the above. | C |
<Instruct>: Given the context 'In the native form, Translin polypeptides form a multimeric structure which is responsible for its DNA binding activity.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (glycine max) (aka translin)
B: translin-like (bos taurus) (aka translin-like)
C: translin (bos taurus) (aka translin)
D: translin (homo sapiens) (aka translin)
E: translin (drosophila melanogaster) (aka translin)
F: None of the above. | D |
<Instruct>: Given the context 'Nuclear localization of Translin is limited to lymphoid cell lines, raising the intriguing possibility that nuclear transport of Translin is regulated in a physiologically significant way such that active nuclear transport is associated with the lymphoid specific process known as Ig/TCR gene rearrangement.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (drosophila melanogaster) (aka translin)
B: translin (danio rerio) (aka translin)
C: translin-like (bos taurus) (aka translin-like)
D: translin-like (xenopus tropicalis) (aka translin-like)
E: translin (homo sapiens) (aka translin)
F: None of the above. | E |
<Instruct>: Given the context 'Nuclear localization of Translin is limited to lymphoid cell lines, raising the intriguing possibility that nuclear transport of Translin is regulated in a physiologically significant way such that active nuclear transport is associated with the lymphoid specific process known as Ig/TCR gene rearrangement.', select the correct biomedical concept corresponding to 'translin'. Answer using one of the provided options. | <Options>: A: translin (mus musculus) (aka translin)
B: translin (xenopus tropicalis) (aka translin)
C: translin (homo sapiens) (aka translin)
D: translin (danio rerio) (aka translin)
E: translin (glycine max) (aka translin)
F: None of the above. | C |
<Instruct>: Given the context 'Marked deficiency of muscle adhalin, a 50 kDa sarcolemmal dystrophin-associated glycoprotein, has been reported in severe childhood autosomal recessive muscular dystrophy (SCARMD).', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: adhalin (xenopus tropicalis) (aka sarcoglycan alpha)
B: dystonin (homo sapiens) (aka dystonin)
C: adhalin (homo sapiens) (aka sarcoglycan alpha)
D: anln (homo sapiens) (aka anillin, actin binding protein)
E: arcadlin (homo sapiens) (aka protocadherin 8)
F: None of the above. | C |
<Instruct>: Given the context 'Marked deficiency of muscle adhalin, a 50 kDa sarcolemmal dystrophin-associated glycoprotein, has been reported in severe childhood autosomal recessive muscular dystrophy (SCARMD).', select the correct biomedical concept corresponding to '50 kda sarcolemmal dystrophin-associated glycoprotein'. Answer using one of the provided options. | <Options>: A: 35kda (mus musculus) (sarcoglycan, gamma (dystrophin-associated glycoprotein) (mus musculus)) (aka sarcoglycan, gamma (dystrophin-associated glycoprotein))
B: sarcoglycan, beta (dystrophin-associated glycoprotein) (mus musculus) (aka sarcoglycan, beta (dystrophin-associated glycoprotein))
C: ankyrin repeat domain 50 (mus musculus) (aka ankyrin repeat domain 50)
D: dctn-50 (mus musculus) (aka dynactin 2)
E: 50dag (homo sapiens) (aka sarcoglycan alpha)
F: None of the above. | E |
<Instruct>: Given the context 'Adhalin deficiency has been found in SCARMD patients from North Africa Europe, Brazil, Japan and North America (SLR & KPC, unpublished data).', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: anln (homo sapiens) (aka anillin, actin binding protein)
B: adhalin (xenopus laevis) (aka sarcoglycan alpha l homeolog)
C: adhalin (homo sapiens) (aka sarcoglycan alpha)
D: dystonin (homo sapiens) (aka dystonin)
E: apln (homo sapiens) (aka apelin)
F: None of the above. | C |
<Instruct>: Given the context 'The disease was initially linked to an unidentified gene on chromosome 13 in families from North Africa, and to the adhalin gene itself on chromosome 17q in one French family in which missense mutations were identified.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: anillin, actin binding protein (homo sapiens) (aka anillin, actin binding protein)
B: arcadlin (homo sapiens) (aka protocadherin 8)
C: ankyrin-1-like (danio rerio) (aka ankyrin-1-like)
D: adhalin (homo sapiens) (aka sarcoglycan alpha)
E: adhalin (xenopus tropicalis) (aka sarcoglycan alpha)
F: None of the above. | D |
<Instruct>: Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: dystonin (homo sapiens) (aka dystonin)
B: adhalin (homo sapiens) (aka sarcoglycan alpha)
C: anln (homo sapiens) (aka anillin, actin binding protein)
D: arcadlin (homo sapiens) (aka protocadherin 8)
E: adhalin (xenopus tropicalis) (aka sarcoglycan alpha)
F: None of the above. | B |
<Instruct>: Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: arcadlin (homo sapiens) (aka protocadherin 8)
B: adhalin (xenopus tropicalis) (aka sarcoglycan alpha)
C: dystonin (homo sapiens) (aka dystonin)
D: ankyrin-1-like (danio rerio) (aka ankyrin-1-like)
E: adhalin (homo sapiens) (aka sarcoglycan alpha)
F: None of the above. | E |
<Instruct>: Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: apln (homo sapiens) (aka apelin)
B: anillin, actin binding protein (homo sapiens) (aka anillin, actin binding protein)
C: adn (homo sapiens) (aka complement factor d)
D: dystonin (homo sapiens) (aka dystonin)
E: adhalin (xenopus laevis) (aka sarcoglycan alpha l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Thus there are two kinds of myopathies with adhalin deficiency: one with a primary defect of adhalin (primary adhalinopathies), and one in which absence of adhalin is secondary to a separate gene defect on chromosome 13.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: arcadlin (homo sapiens) (aka protocadherin 8)
B: adn (homo sapiens) (aka complement factor d)
C: dystonin (homo sapiens) (aka dystonin)
D: adhalin (homo sapiens) (aka sarcoglycan alpha)
E: anillin, actin binding protein (homo sapiens) (aka anillin, actin binding protein)
F: None of the above. | D |
<Instruct>: Given the context 'We have examined the importance of primary adhalinopathies among myopathies with adhalin deficiency, and describe several additional mutations (null and missense) in the adhalin gene in 10 new families from Europe and North Africa.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: ankyrin-1-like (danio rerio) (aka ankyrin-1-like)
B: adhalin (xenopus laevis) (aka sarcoglycan alpha l homeolog)
C: adn (homo sapiens) (aka complement factor d)
D: dystonin (homo sapiens) (aka dystonin)
E: adhalin (homo sapiens) (aka sarcoglycan alpha)
F: None of the above. | E |
<Instruct>: Given the context 'We have examined the importance of primary adhalinopathies among myopathies with adhalin deficiency, and describe several additional mutations (null and missense) in the adhalin gene in 10 new families from Europe and North Africa.', select the correct biomedical concept corresponding to 'adhalin'. Answer using one of the provided options. | <Options>: A: adhalin (xenopus laevis) (aka sarcoglycan alpha l homeolog)
B: anln (homo sapiens) (aka anillin, actin binding protein)
C: adhalin (homo sapiens) (aka sarcoglycan alpha)
D: arcadlin (homo sapiens) (aka protocadherin 8)
E: apln (homo sapiens) (aka apelin)
F: None of the above. | C |
<Instruct>: Given the context 'Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.
', select the correct biomedical concept corresponding to 'macrophage inflammatory protein 1 alpha'. Answer using one of the provided options. | <Options>: A: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
B: c-x-c motif chemokine ligand 1 (homo sapiens) (aka c-x-c motif chemokine ligand 1)
C: mcp-1 (homo sapiens) (aka c-c motif chemokine ligand 2)
D: mip1ap (homo sapiens) (aka c-c motif chemokine ligand 3 like 1)
E: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3)
F: None of the above. | F |
<Instruct>: Given the context 'Structure and functional expression of the human macrophage inflammatory protein 1 alpha/RANTES receptor.
', select the correct biomedical concept corresponding to 'rantes receptor'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine receptor 6 (homo sapiens) (aka c-c motif chemokine receptor 6)
B: c-x3-c motif chemokine receptor 1 (homo sapiens) (aka c-x3-c motif chemokine receptor 1)
C: c-c motif chemokine receptor 2 (homo sapiens) (aka c-c motif chemokine receptor 2)
D: c-c motif chemokine receptor 1 (homo sapiens) (aka c-c motif chemokine receptor 1)
E: c-c motif chemokine receptor 3 (homo sapiens) (aka c-c motif chemokine receptor 3)
F: None of the above. | D |
<Instruct>: Given the context 'The chemokine beta family is comprised of at least six distinct cytokines that regulate trafficking of phagocytes and lymphocytes in mammalian species; at least one of these, macrophage inflammatory protein 1 alpha (MIP-1 alpha), also regulates the growth of hematopoietic stem cells.', select the correct biomedical concept corresponding to 'macrophage inflammatory protein 1 alpha'. Answer using one of the provided options. | <Options>: A: c-x-c motif chemokine ligand 1 (homo sapiens) (aka c-x-c motif chemokine ligand 1)
B: mip-3-alpha (homo sapiens) (aka c-c motif chemokine ligand 20)
C: mip1ap (homo sapiens) (aka c-c motif chemokine ligand 3 like 1)
D: mcp-1 (homo sapiens) (aka c-c motif chemokine ligand 2)
E: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
F: None of the above. | F |
<Instruct>: Given the context 'The chemokine beta family is comprised of at least six distinct cytokines that regulate trafficking of phagocytes and lymphocytes in mammalian species; at least one of these, macrophage inflammatory protein 1 alpha (MIP-1 alpha), also regulates the growth of hematopoietic stem cells.', select the correct biomedical concept corresponding to 'mip-1 alpha'. Answer using one of the provided options. | <Options>: A: mip-3a (homo sapiens) (aka c-c motif chemokine ligand 20)
B: mip1b (homo sapiens) (aka c-c motif chemokine ligand 4)
C: mip1ap (homo sapiens) (aka c-c motif chemokine ligand 3 like 1)
D: c-c motif chemokine ligand 1 (homo sapiens) (aka c-c motif chemokine ligand 1)
E: c-x3-c motif chemokine ligand 1 (homo sapiens) (aka c-x3-c motif chemokine ligand 1)
F: None of the above. | F |
<Instruct>: Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', select the correct biomedical concept corresponding to 'mip-1 alpha'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine ligand 1 (homo sapiens) (aka c-c motif chemokine ligand 1)
B: mip-1-alpha (homo sapiens) (aka c-c motif chemokine ligand 3)
C: mip1ap (homo sapiens) (aka c-c motif chemokine ligand 3 like 1)
D: c-x3-c motif chemokine ligand 1 (homo sapiens) (aka c-x3-c motif chemokine ligand 1)
E: mip-1d (homo sapiens) (aka c-c motif chemokine ligand 15)
F: None of the above. | F |
<Instruct>: Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', select the correct biomedical concept corresponding to 'beta chemokine'. Answer using one of the provided options. | <Options>: A: mip-3b (homo sapiens) (aka c-c motif chemokine ligand 19)
B: mip-1-beta (xenopus tropicalis) (aka c-c motif chemokine ligand 4)
C: rantes (homo sapiens) (aka c-c motif chemokine ligand 5)
D: mip-1-beta (homo sapiens) (c-c motif chemokine ligand 4 (homo sapiens)) (aka c-c motif chemokine ligand 4)
E: c-c motif chemokine ligand 2 (homo sapiens) (aka c-c motif chemokine ligand 2)
F: None of the above. | C |
<Instruct>: Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', select the correct biomedical concept corresponding to 'rantes'. Answer using one of the provided options. | <Options>: A: c-c motif chemokine 3 (sus scrofa) (aka c-c motif chemokine 3)
B: rantes (sus scrofa) (aka c-c motif chemokine ligand 5)
C: rantes (xenopus tropicalis) (aka chemokine (c-c motif) ligand 5)
D: scya5 (homo sapiens) (aka c-c motif chemokine ligand 5)
E: scya7 (homo sapiens) (aka c-c motif chemokine ligand 7)
F: None of the above. | D |
<Instruct>: Given the context 'We now show that MIP-1 alpha and the related beta chemokine, RANTES, induce transient alterations in intracellular Ca2+ concentration in polymorphonuclear leukocytes that can be reciprocally and specifically desensitized, suggesting a common receptor.', select the correct biomedical concept corresponding to 'rantes'. Answer using one of the provided options. | <Options>: A: rantes (sus scrofa) (aka c-c motif chemokine ligand 5)
B: mcp-3 (homo sapiens) (aka c-c motif chemokine ligand 7)
C: c-c motif chemokine 3 (sus scrofa) (aka c-c motif chemokine 3)
D: rantes (xenopus tropicalis) (aka chemokine (c-c motif) ligand 5)
E: ccl25 (homo sapiens) (aka c-c motif chemokine ligand 25)
F: None of the above. | F |
<Instruct>: Given the context 'It has approximately 33% amino acid identity with receptors for the alpha chemokine, interleukin 8, and may be the human homologue of the product of US28, an open reading frame of human cytomegalovirus.', select the correct biomedical concept corresponding to 'alpha chemokine'. Answer using one of the provided options. | <Options>: A: groa (homo sapiens) (aka c-x-c motif chemokine ligand 1)
B: ifn-alphaa (homo sapiens) (aka interferon alpha 2)
C: rantes (homo sapiens) (aka c-c motif chemokine ligand 5)
D: ifn-alphac (homo sapiens) (aka interferon alpha 10)
E: c3xkine (homo sapiens) (aka c-x3-c motif chemokine ligand 1)
F: None of the above. | F |
<Instruct>: Given the context 'It has approximately 33% amino acid identity with receptors for the alpha chemokine, interleukin 8, and may be the human homologue of the product of US28, an open reading frame of human cytomegalovirus.', select the correct biomedical concept corresponding to 'interleukin 8'. Answer using one of the provided options. | <Options>: A: fgf-8 (homo sapiens) (aka fibroblast growth factor 8)
B: il18 (homo sapiens) (aka interleukin 18)
C: il-1f8 (homo sapiens) (aka interleukin 36 beta)
D: cxcl8 (homo sapiens) (aka c-x-c motif chemokine ligand 8)
E: ccl8 (homo sapiens) (aka c-c motif chemokine ligand 8)
F: None of the above. | D |
<Instruct>: Given the context 'p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
B: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
C: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
D: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
E: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
F: None of the above. | E |
<Instruct>: Given the context 'p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.
', select the correct biomedical concept corresponding to 'p21cip1'. Answer using one of the provided options. | <Options>: A: cdkn1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1a)
B: inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens) (aka inhibitor of cdk, cyclin a1 interacting protein 1)
C: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
D: p-cip1 (homo sapiens) (aka ras association domain family member 9)
E: p21cip1 (xenopus tropicalis) (aka cyclin-dependent kinase inhibitor 1a)
F: None of the above. | A |
<Instruct>: Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens)) (aka calcium and integrin binding family member 2)
B: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
C: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
D: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
E: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
F: None of the above. | E |
<Instruct>: Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', select the correct biomedical concept corresponding to 'p21cip1'. Answer using one of the provided options. | <Options>: A: cdkn1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1a)
B: inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens) (aka inhibitor of cdk, cyclin a1 interacting protein 1)
C: p21cip1 (xenopus tropicalis) (aka cyclin-dependent kinase inhibitor 1a)
D: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
E: p-cip1 (homo sapiens) (aka ras association domain family member 9)
F: None of the above. | A |
<Instruct>: Given the context 'We describe a new CKI, p57KIP2, which is related to p21CIP1 and p27KIP1.', select the correct biomedical concept corresponding to 'p27kip1'. Answer using one of the provided options. | <Options>: A: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
B: p27kip1 (xenopus tropicalis) (aka cyclin-dependent kinase inhibitor 1b (p27, kip1))
C: cdkn1b (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
D: p27k (homo sapiens) (aka proteasome 20s subunit alpha 6)
E: cyclin dependent kinase inhibitor 1a (homo sapiens) (aka cyclin dependent kinase inhibitor 1a)
F: None of the above. | C |
<Instruct>: Given the context 'p57KIP2 is a potent, tight-binding inhibitor of several G1 cyclin/Cdk complexes, and its binding is cyclin dependent.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
C: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
D: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
E: kish2 (homo sapiens) (aka chromodomain helicase dna binding protein 9)
F: None of the above. | D |
<Instruct>: Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', select the correct biomedical concept corresponding to 'cip1'. Answer using one of the provided options. | <Options>: A: p21cip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1a)
B: ckip-1 (homo sapiens) (aka pleckstrin homology domain containing o1)
C: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
D: cip2a (homo sapiens) (aka cellular inhibitor of pp2a)
E: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
F: None of the above. | A |
<Instruct>: Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: ing2 (homo sapiens) (inhibitor of growth family member 2 (homo sapiens)) (aka inhibitor of growth family member 2)
B: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
C: cdkn2b (homo sapiens) (aka cyclin dependent kinase inhibitor 2b)
D: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
E: kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens)) (aka calcium and integrin binding family member 2)
F: None of the above. | D |
<Instruct>: Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
B: kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens)) (aka calcium and integrin binding family member 2)
C: cyclin dependent kinase inhibitor 2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
D: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
E: cdkn2b (homo sapiens) (aka cyclin dependent kinase inhibitor 2b)
F: None of the above. | F |
<Instruct>: Given the context 'Unlike CIP1, KIP2 is not regulated by p53.', select the correct biomedical concept corresponding to 'p53'. Answer using one of the provided options. | <Options>: A: tp53 (homo sapiens) (aka tumor protein p53)
B: ct53 (homo sapiens) (aka zinc finger protein 165)
C: rad53 (homo sapiens) (aka checkpoint kinase 2)
D: p532 (homo sapiens) (aka hect and rld domain containing e3 ubiquitin protein ligase family member 1)
E: p53cp (homo sapiens) (aka tumor protein p63)
F: None of the above. | A |
<Instruct>: Given the context 'Overexpression of p57KIP2 arrests cells in G1.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: kish2 (homo sapiens) (aka chromodomain helicase dna binding protein 9)
B: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
C: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
D: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
E: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
F: None of the above. | B |
<Instruct>: Given the context 'p57KIP2 proteins have a complex structure.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
B: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
C: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
D: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
E: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
F: None of the above. | B |
<Instruct>: Given the context 'Mouse p57KIP2 consists of four structurally distinct domains: an amino-terminal Cdk inhibitory domain, a proline-rich domain, an acidic-repeat region, and a carboxy-terminal domain conserved with p27KIP1.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
C: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
D: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
E: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
F: None of the above. | D |
<Instruct>: Given the context 'Mouse p57KIP2 consists of four structurally distinct domains: an amino-terminal Cdk inhibitory domain, a proline-rich domain, an acidic-repeat region, and a carboxy-terminal domain conserved with p27KIP1.', select the correct biomedical concept corresponding to 'p27kip1'. Answer using one of the provided options. | <Options>: A: p27k (homo sapiens) (aka proteasome 20s subunit alpha 6)
B: cyclin-dependent kinase inhibitor 1b (p27, kip1) (xenopus tropicalis) (aka cyclin-dependent kinase inhibitor 1b (p27, kip1))
C: cyclin dependent kinase inhibitor 1a (homo sapiens) (aka cyclin dependent kinase inhibitor 1a)
D: kip1 (homo sapiens) (cyclin dependent kinase inhibitor 1b (homo sapiens)) (aka cyclin dependent kinase inhibitor 1b)
E: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
F: None of the above. | D |
<Instruct>: Given the context 'Human p57KIP2 appears to have conserved the amino- and carboxy-terminal domains but has replaced the internal regions with sequences containing proline-alanine repeats.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
C: kish2 (homo sapiens) (aka chromodomain helicase dna binding protein 9)
D: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
E: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
F: None of the above. | B |
<Instruct>: Given the context 'In situ hybridization during mouse embryogenesis revealed that KIP2 mRNA displays a striking pattern of expression during development, showing high level expression in skeletal muscle, brain, heart, lungs, and eye.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
B: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
C: kip2 (homo sapiens) (cyclin dependent kinase inhibitor 1c (homo sapiens)) (aka cyclin dependent kinase inhibitor 1c)
D: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
E: ing2 (homo sapiens) (inhibitor of growth family member 2 (homo sapiens)) (aka inhibitor of growth family member 2)
F: None of the above. | C |
<Instruct>: Given the context 'Most of the KIP2-expressing cells are terminally differentiated, suggesting that p57KIP2 is involved in decisions to exit the cell cycle during development and differentiation.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: cyclin dependent kinase inhibitor 2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: cdkn2b (homo sapiens) (aka cyclin dependent kinase inhibitor 2b)
C: kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens)) (aka calcium and integrin binding family member 2)
D: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
E: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
F: None of the above. | E |
<Instruct>: Given the context 'Most of the KIP2-expressing cells are terminally differentiated, suggesting that p57KIP2 is involved in decisions to exit the cell cycle during development and differentiation.', select the correct biomedical concept corresponding to 'p57kip2'. Answer using one of the provided options. | <Options>: A: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
B: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
C: cdkn2 (homo sapiens) (cyclin dependent kinase 2 (homo sapiens)) (aka cyclin dependent kinase 2)
D: kish2 (homo sapiens) (aka chromodomain helicase dna binding protein 9)
E: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
F: None of the above. | E |
<Instruct>: Given the context 'Human KIP2 is located at 11p15.5, a region implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, a familial cancer syndrome, marking it as a candidate tumor suppressor.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: cip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 3)
C: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
D: p57kip2 (homo sapiens) (aka cyclin dependent kinase inhibitor 1c)
E: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
F: None of the above. | D |
<Instruct>: Given the context 'Human KIP2 is located at 11p15.5, a region implicated in both sporadic cancers and Beckwith-Wiedemann syndrome, a familial cancer syndrome, marking it as a candidate tumor suppressor.', select the correct biomedical concept corresponding to 'kip2'. Answer using one of the provided options. | <Options>: A: cdkn2c (homo sapiens) (aka cyclin dependent kinase inhibitor 2c)
B: kip2 (homo sapiens) (calcium and integrin binding family member 2 (homo sapiens)) (aka calcium and integrin binding family member 2)
C: calcium/calmodulin dependent protein kinase ii inhibitor 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase ii inhibitor 2)
D: p-cip2 (homo sapiens) (aka u2af homology motif kinase 1)
E: ing2 (homo sapiens) (inhibitor of growth family member 2 (homo sapiens)) (aka inhibitor of growth family member 2)
F: None of the above. | F |
<Instruct>: Given the context 'The discovery of a new member of the p21CIP1 inhibitor family with novel structural features and expression patterns suggests a complex role for these proteins in cell cycle control and development.', select the correct biomedical concept corresponding to 'p21cip1'. Answer using one of the provided options. | <Options>: A: inhibitor of cdk, cyclin a1 interacting protein 1 (homo sapiens) (aka inhibitor of cdk, cyclin a1 interacting protein 1)
B: p-cip1 (homo sapiens) (aka ras association domain family member 9)
C: p21cip1 (xenopus tropicalis) (aka cyclin-dependent kinase inhibitor 1a)
D: p27kip1 (homo sapiens) (aka cyclin dependent kinase inhibitor 1b)
E: cip1 (homo sapiens) (cyclin dependent kinase inhibitor 1a (homo sapiens)) (aka cyclin dependent kinase inhibitor 1a)
F: None of the above. | E |
<Instruct>: Given the context 'A novel human protease similar to the interleukin-1 beta converting enzyme induces apoptosis in transfected cells.
', select the correct biomedical concept corresponding to 'interleukin-1 beta converting enzyme'. Answer using one of the provided options. | <Options>: A: casp16 (homo sapiens) (aka caspase 16, pseudogene)
B: casp2 (homo sapiens) (aka caspase 2)
C: casp3 (homo sapiens) (aka caspase 3)
D: caspase 1 (homo sapiens) (aka caspase 1)
E: ice1 (homo sapiens) (aka interactor of little elongation complex ell subunit 1)
F: None of the above. | D |
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