instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'With a zoo blot analysis, human Rep-8 DNA hybridized strongly with the monkey DNA, but only weakly with the DNAs of species other than Homo sapiens.', select the correct biomedical concept corresponding to 'rep-8'. Answer using one of the provided options. | <Options>: A: rep8 (homo sapiens) (aka ubx domain protein 8)
B: rep-8 (mus musculus) (aka ubx domain protein 8)
C: rep-1 (homo sapiens) (aka chm rab escort protein)
D: atp-dependent dna helicase rep (escherichia coli str. k-12 substr. mg1655) (aka atp-dependent dna helicase rep)
E: rep8 (xenopus laevis) (aka ubx domain protein 8 l homeolog)
F: None of the above. | A |
<Instruct>: Given the context 'Northern blot analysis showed that it is expressed abundantly in the testis and ovary, suggesting that the Rep-8 gene product may play a role in reproduction.', select the correct biomedical concept corresponding to 'rep-8'. Answer using one of the provided options. | <Options>: A: rep15 (homo sapiens) (aka rab15 effector protein)
B: rep8 (homo sapiens) (aka ubx domain protein 8)
C: rep-1 (homo sapiens) (aka chm rab escort protein)
D: rep8h (mus musculus) (aka ubx domain protein 8)
E: rep8 (xenopus tropicalis) (aka ubx domain protein 8)
F: None of the above. | B |
<Instruct>: Given the context 'Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
B: kit proto-oncogene, receptor tyrosine kinase (sus scrofa) (aka kit proto-oncogene, receptor tyrosine kinase)
C: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
D: kit proto-oncogene, receptor tyrosine kinase (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
E: kitl (homo sapiens) (aka kit ligand)
F: None of the above. | D |
<Instruct>: Given the context 'Sequence analysis of two genomic regions containing the KIT and the FMS receptor tyrosine kinase genes.
', select the correct biomedical concept corresponding to 'fms'. Answer using one of the provided options. | <Options>: A: fms (escherichia coli str. k-12 substr. mg1655) (aka peptide deformylase)
B: fms related receptor tyrosine kinase 3 (homo sapiens) (aka fms related receptor tyrosine kinase 3)
C: flt-1 (homo sapiens) (aka fms related receptor tyrosine kinase 1)
D: colony stimulating factor 1 receptor (homo sapiens) (aka colony stimulating factor 1 receptor)
E: fms related receptor tyrosine kinase 4 (homo sapiens) (aka fms related receptor tyrosine kinase 4)
F: None of the above. | D |
<Instruct>: Given the context 'The KIT and FMS tyrosine kinase receptors, which are implicated in the control of cell growth and differentiation, stem through duplications from a common ancestor.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
B: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
C: kitl (homo sapiens) (aka kit ligand)
D: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
E: cd117 (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'The KIT and FMS tyrosine kinase receptors, which are implicated in the control of cell growth and differentiation, stem through duplications from a common ancestor.', select the correct biomedical concept corresponding to 'fms'. Answer using one of the provided options. | <Options>: A: fms (mus musculus) (aka colony stimulating factor 1 receptor)
B: fms related receptor tyrosine kinase 1 (homo sapiens) (aka fms related receptor tyrosine kinase 1)
C: fms (escherichia coli str. k-12 substr. mg1655) (aka peptide deformylase)
D: fms related receptor tyrosine kinase 3 (homo sapiens) (aka fms related receptor tyrosine kinase 3)
E: csf1r (homo sapiens) (aka colony stimulating factor 1 receptor)
F: None of the above. | E |
<Instruct>: Given the context 'We have conducted a detailed structural analysis of the two loci containing the KIT and FMS genes.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
B: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
C: kit proto-oncogene, receptor tyrosine kinase (sus scrofa) (aka kit proto-oncogene, receptor tyrosine kinase)
D: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
E: c-kit (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
F: None of the above. | E |
<Instruct>: Given the context 'We have conducted a detailed structural analysis of the two loci containing the KIT and FMS genes.', select the correct biomedical concept corresponding to 'fms'. Answer using one of the provided options. | <Options>: A: fms (mus musculus) (aka colony stimulating factor 1 receptor)
B: flt-1 (homo sapiens) (aka fms related receptor tyrosine kinase 1)
C: fms related receptor tyrosine kinase 3 (homo sapiens) (aka fms related receptor tyrosine kinase 3)
D: fms (escherichia coli str. k-12 substr. mg1655) (aka peptide deformylase)
E: fms (homo sapiens) (aka colony stimulating factor 1 receptor)
F: None of the above. | E |
<Instruct>: Given the context 'The sequence of the approximately 90-kb KIT locus reveals the position and size of the 21 introns and of the 5' regulatory region of the KIT gene.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
B: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
C: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
D: c-kit (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
E: kitl (homo sapiens) (aka kit ligand)
F: None of the above. | D |
<Instruct>: Given the context 'The sequence of the approximately 90-kb KIT locus reveals the position and size of the 21 introns and of the 5' regulatory region of the KIT gene.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: kit (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
B: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
C: kit proto-oncogene, receptor tyrosine kinase (sus scrofa) (aka kit proto-oncogene, receptor tyrosine kinase)
D: kit ligand (homo sapiens) (aka kit ligand)
E: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
F: None of the above. | A |
<Instruct>: Given the context 'The sequence of the approximately 90-kb KIT locus reveals the position and size of the 21 introns and of the 5' regulatory region of the KIT gene.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: kitl (homo sapiens) (aka kit ligand)
B: kit proto-oncogene, receptor tyrosine kinase (sus scrofa) (aka kit proto-oncogene, receptor tyrosine kinase)
C: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
D: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
E: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
F: None of the above. | F |
<Instruct>: Given the context 'The introns and the 3'-untranslated parts of KIT and FMS have been analyzed in parallel.', select the correct biomedical concept corresponding to 'kit'. Answer using one of the provided options. | <Options>: A: cd117 (homo sapiens) (aka kit proto-oncogene, receptor tyrosine kinase)
B: kit proto-oncogene, receptor tyrosine kinase (gallus gallus) (aka kit proto-oncogene, receptor tyrosine kinase)
C: kit proto-oncogene, receptor tyrosine kinase (sus scrofa) (aka kit proto-oncogene, receptor tyrosine kinase)
D: kit proto-oncogene receptor tyrosine kinase (mus musculus) (aka kit proto-oncogene receptor tyrosine kinase)
E: cd116 (homo sapiens) (aka colony stimulating factor 2 receptor subunit alpha)
F: None of the above. | A |
<Instruct>: Given the context 'The introns and the 3'-untranslated parts of KIT and FMS have been analyzed in parallel.', select the correct biomedical concept corresponding to 'fms'. Answer using one of the provided options. | <Options>: A: colony stimulating factor 1 receptor (homo sapiens) (aka colony stimulating factor 1 receptor)
B: fms related receptor tyrosine kinase 3 (homo sapiens) (aka fms related receptor tyrosine kinase 3)
C: fms (escherichia coli str. k-12 substr. mg1655) (aka peptide deformylase)
D: flt-1 (homo sapiens) (aka fms related receptor tyrosine kinase 1)
E: fms related receptor tyrosine kinase 4 (homo sapiens) (aka fms related receptor tyrosine kinase 4)
F: None of the above. | A |
<Instruct>: Given the context 'These programs led us to identify a novel gene, designated SMF, immediately downstream of FMS, in the opposite orientation.', select the correct biomedical concept corresponding to 'smf'. Answer using one of the provided options. | <Options>: A: small ribonucleoprotein particle protein smf (drosophila melanogaster) (aka small ribonucleoprotein particle protein smf)
B: sm-f (homo sapiens) (aka small nuclear ribonucleoprotein polypeptide f)
C: ssf1 (mus musculus) (aka peter pan homolog)
D: shf (mus musculus) (aka src homology 2 domain containing f)
E: myhsf (mus musculus) (aka myosin, heavy polypeptide 4, skeletal muscle)
F: None of the above. | F |
<Instruct>: Given the context 'These programs led us to identify a novel gene, designated SMF, immediately downstream of FMS, in the opposite orientation.', select the correct biomedical concept corresponding to 'fms'. Answer using one of the provided options. | <Options>: A: c-fms (homo sapiens) (aka colony stimulating factor 1 receptor)
B: flt-1 (homo sapiens) (aka fms related receptor tyrosine kinase 1)
C: fms (escherichia coli str. k-12 substr. mg1655) (aka peptide deformylase)
D: fms (mus musculus) (aka colony stimulating factor 1 receptor)
E: fms related receptor tyrosine kinase 3 (homo sapiens) (aka fms related receptor tyrosine kinase 3)
F: None of the above. | A |
<Instruct>: Given the context 'We have isolated the full-length human 56 kDa selenium binding protein (hSP56) cDNA clone, which is the human homolog of mouse 56 kDa selenium binding protein.', select the correct biomedical concept corresponding to '56 kda selenium binding protein'. Answer using one of the provided options. | <Options>: A: sbp56 (xenopus laevis) (selenium binding protein 1 l homeolog (xenopus laevis)) (aka selenium binding protein 1 l homeolog)
B: selenium binding protein 1 (homo sapiens) (aka selenium binding protein 1)
C: selenium binding protein 1 (bos taurus) (aka selenium binding protein 1)
D: sp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis)) (aka selenium binding protein 1 s homeolog)
E: selenium binding protein 1 (gallus gallus) (aka selenium binding protein 1)
F: None of the above. | B |
<Instruct>: Given the context 'We have isolated the full-length human 56 kDa selenium binding protein (hSP56) cDNA clone, which is the human homolog of mouse 56 kDa selenium binding protein.', select the correct biomedical concept corresponding to 'hsp56'. Answer using one of the provided options. | <Options>: A: hsp56 (homo sapiens) (aka fkbp prolyl isomerase 4)
B: sp56 (homo sapiens) (aka selenium binding protein 1)
C: hca56 (homo sapiens) (aka eukaryotic translation initiation factor 2d)
D: pp5656 (homo sapiens) (aka large xylosyl- and glucuronyltransferase 2)
E: prss56 (homo sapiens) (aka serine protease 56)
F: None of the above. | B |
<Instruct>: Given the context 'We have isolated the full-length human 56 kDa selenium binding protein (hSP56) cDNA clone, which is the human homolog of mouse 56 kDa selenium binding protein.', select the correct biomedical concept corresponding to '56 kda selenium binding protein'. Answer using one of the provided options. | <Options>: A: selenbp1 (homo sapiens) (aka selenium binding protein 1)
B: selenium binding protein 1 (gallus gallus) (aka selenium binding protein 1)
C: selenium binding protein 1 (xenopus tropicalis) (aka selenium binding protein 1)
D: selenium binding protein 1 (bos taurus) (aka selenium binding protein 1)
E: sbp56 (xenopus laevis) (selenium binding protein 1 l homeolog (xenopus laevis)) (aka selenium binding protein 1 l homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Using Northern blot hybridization, we found that this 56 kDa selenium binding protein is expressed in mouse heart with an intermediate level between those found in liver/lung/kidney and intestine.', select the correct biomedical concept corresponding to '56 kda selenium binding protein'. Answer using one of the provided options. | <Options>: A: selenium binding protein 1 (homo sapiens) (aka selenium binding protein 1)
B: selenium binding protein 1 (gallus gallus) (aka selenium binding protein 1)
C: sbp56 (xenopus laevis) (selenium binding protein 1 s homeolog (xenopus laevis)) (aka selenium binding protein 1 s homeolog)
D: sp56 (xenopus laevis) (selenium binding protein 1 l homeolog (xenopus laevis)) (aka selenium binding protein 1 l homeolog)
E: selenium binding protein 1 (bos taurus) (aka selenium binding protein 1)
F: None of the above. | A |
<Instruct>: Given the context 'We have also successfully expressed hSP56 in Escherichia coli using the expression vector-pAED4.', select the correct biomedical concept corresponding to 'hsp56'. Answer using one of the provided options. | <Options>: A: ppp1r56 (homo sapiens) (aka caspase 9)
B: prss56 (homo sapiens) (aka serine protease 56)
C: sp56 (homo sapiens) (aka selenium binding protein 1)
D: pp5656 (homo sapiens) (aka large xylosyl- and glucuronyltransferase 2)
E: hca56 (homo sapiens) (aka eukaryotic translation initiation factor 2d)
F: None of the above. | C |
<Instruct>: Given the context 'The hSP56 gene is located at human chromosome 1q21-22).', select the correct biomedical concept corresponding to 'hsp56'. Answer using one of the provided options. | <Options>: A: sbp56 (homo sapiens) (aka selenium binding protein 1)
B: hc56 (homo sapiens) (aka gem nuclear organelle associated protein 4)
C: ppp1r56 (homo sapiens) (aka caspase 9)
D: hsp56 (homo sapiens) (aka fkbp prolyl isomerase 4)
E: ss56 (homo sapiens) (aka tripartite motif containing 68)
F: None of the above. | A |
<Instruct>: Given the context 'The hSP56 gene is located at human chromosome 1q21-22).', select the correct biomedical concept corresponding to 'hsp56'. Answer using one of the provided options. | <Options>: A: ppp1r56 (homo sapiens) (aka caspase 9)
B: hsp56 (homo sapiens) (aka fkbp prolyl isomerase 4)
C: spg56 (homo sapiens) (aka cytochrome p450 family 2 subfamily u member 1)
D: hc56 (homo sapiens) (aka gem nuclear organelle associated protein 4)
E: hca56 (homo sapiens) (aka eukaryotic translation initiation factor 2d)
F: None of the above. | F |
<Instruct>: Given the context 'We have cloned a novel serine/threonine protein kinase (PK428) which is highly related (65%) within the kinase domain to the myotonic dystrophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
B: cg32428 (drosophila melanogaster) (aka uncharacterized protein)
C: l(2)k09828 (drosophila melanogaster) (aka mitochondrial trifunctional protein beta subunit)
D: l(2)k05428 (drosophila melanogaster) (aka dribble)
E: su(tor)2-408 (drosophila melanogaster) (aka su(tor)2-408)
F: None of the above. | A |
<Instruct>: Given the context 'We have cloned a novel serine/threonine protein kinase (PK428) which is highly related (65%) within the kinase domain to the myotonic dystrophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).', select the correct biomedical concept corresponding to 'myotonic dystrophy protein kinase'. Answer using one of the provided options. | <Options>: A: dtk (mus musculus) (aka tyro3 protein tyrosine kinase 3)
B: dm1 protein kinase (homo sapiens) (aka dm1 protein kinase)
C: deoxythymidylate kinase (mus musculus) (aka deoxythymidylate kinase)
D: protein kinase d2 (mus musculus) (aka protein kinase d2)
E: dm (mus musculus) (dystrophia myotonica-protein kinase (mus musculus)) (aka dystrophia myotonica-protein kinase)
F: None of the above. | B |
<Instruct>: Given the context 'We have cloned a novel serine/threonine protein kinase (PK428) which is highly related (65%) within the kinase domain to the myotonic dystrophy protein kinase (DM-PK), as well as the cyclic AMP-dependent protein kinase (33%).', select the correct biomedical concept corresponding to 'dm-pk'. Answer using one of the provided options. | <Options>: A: pkm (drosophila melanogaster) (pyruvate kinase (drosophila melanogaster)) (aka pyruvate kinase)
B: dm (mus musculus) (dystrophia myotonica-protein kinase (mus musculus)) (aka dystrophia myotonica-protein kinase)
C: dmk (drosophila melanogaster) (aka kinesin heavy chain)
D: drm-pk-1 (drosophila melanogaster) (aka capability)
E: dmkp (drosophila melanogaster) (aka map kinase-specific phosphatase)
F: None of the above. | F |
<Instruct>: Given the context 'Northern blots demonstrate that PK428 mRNA is distributed widely among tissues and is expressed at the highest levels in pancreas, heart, and skeletal muscle, with lower levels in liver and lung.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: cg42828 (drosophila melanogaster) (aka uncharacterized protein)
B: su(tor)2-408 (drosophila melanogaster) (aka su(tor)2-408)
C: cg43428 (drosophila melanogaster) (aka uncharacterized protein)
D: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
E: l(2)k09828 (drosophila melanogaster) (aka mitochondrial trifunctional protein beta subunit)
F: None of the above. | D |
<Instruct>: Given the context 'Two PK428 mRNAs 10 and 3.8 kilobase pairs in size are seen in a number of cell lines, including hematopoietic and breast cancer cells.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: l(2)k09828 (drosophila melanogaster) (aka mitochondrial trifunctional protein beta subunit)
B: l(2)k04218 (drosophila melanogaster) (aka charlatan)
C: cell-pk42 (drosophila melanogaster) (aka maternal effect cellularisation defect c)
D: cg43428 (drosophila melanogaster) (aka uncharacterized protein)
E: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
F: None of the above. | E |
<Instruct>: Given the context 'Immunoprecipitation of the transiently expressed PK428 protein and incubation with [gamma-32P]ATP demonstrate that it is capable of autophosphorylation.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: cg43428 (drosophila melanogaster) (aka uncharacterized protein)
B: pk428 (rattus norvegicus) (aka cdc42 binding protein kinase alpha)
C: l(2)k04218 (drosophila melanogaster) (aka charlatan)
D: l(2)k05428 (drosophila melanogaster) (aka dribble)
E: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
F: None of the above. | E |
<Instruct>: Given the context 'In addition, immunoprecipitates of the PK428 protein kinase also phosphorylated histone H1 and a peptide encoding a cyclic AMP-dependent protein kinase substrate.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: l(2)k04218 (drosophila melanogaster) (aka charlatan)
B: su(tor)2-408 (drosophila melanogaster) (aka su(tor)2-408)
C: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
D: l(2)k05428 (drosophila melanogaster) (aka dribble)
E: cell-pk42 (drosophila melanogaster) (aka maternal effect cellularisation defect c)
F: None of the above. | C |
<Instruct>: Given the context 'The gene corresponding to the 3.8-kb PK428 mRNA, and its corresponding 65-kDa protein, was isolated by polymerase chain reaction screening of a P1 phage human genomic library.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: pk428 (rattus norvegicus) (aka cdc42 binding protein kinase alpha)
B: l(2)k09828 (drosophila melanogaster) (aka mitochondrial trifunctional protein beta subunit)
C: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
D: cg32428 (drosophila melanogaster) (aka uncharacterized protein)
E: cg42828 (drosophila melanogaster) (aka uncharacterized protein)
F: None of the above. | C |
<Instruct>: Given the context 'Using this P1 phage clone as a probe, the PK428 gene was located on 1q41-42, a possible location for a human senescence gene, a gene associated with Rippling muscle disease, as well as a region associated with genetically acquired mental retardation.', select the correct biomedical concept corresponding to 'pk428'. Answer using one of the provided options. | <Options>: A: su(tor)2-408 (drosophila melanogaster) (aka su(tor)2-408)
B: l(2)k04218 (drosophila melanogaster) (aka charlatan)
C: pk428 (homo sapiens) (aka cdc42 binding protein kinase alpha)
D: l(2)k09828 (drosophila melanogaster) (aka mitochondrial trifunctional protein beta subunit)
E: cg43428 (drosophila melanogaster) (aka uncharacterized protein)
F: None of the above. | C |
<Instruct>: Given the context 'Using this P1 phage clone as a probe, the PK428 gene was located on 1q41-42, a possible location for a human senescence gene, a gene associated with Rippling muscle disease, as well as a region associated with genetically acquired mental retardation.', select the correct biomedical concept corresponding to 'a gene associated with rippling muscle disease'. Answer using one of the provided options. | <Options>: A: arv1 homolog, fatty acid homeostasis modulator (gallus gallus) (aka arv1 homolog, fatty acid homeostasis modulator)
B: ras-related associated with diabetes (mus musculus) (aka ras-related associated with diabetes)
C: reactive intermediate imine deaminase a homolog (mus musculus) (aka reactive intermediate imine deaminase a homolog)
D: rmd1 (homo sapiens) (rippling muscle disease 1 (homo sapiens)) (aka rippling muscle disease 1)
E: reactive intermediate imine deaminase a homolog (gallus gallus) (aka reactive intermediate imine deaminase a homolog)
F: None of the above. | D |
<Instruct>: Given the context 'Using this P1 phage clone as a probe, the PK428 gene was located on 1q41-42, a possible location for a human senescence gene, a gene associated with Rippling muscle disease, as well as a region associated with genetically acquired mental retardation.', select the correct biomedical concept corresponding to 'a gene associated with rippling muscle disease'. Answer using one of the provided options. | <Options>: A: arv1 homolog, fatty acid homeostasis modulator (gallus gallus) (aka arv1 homolog, fatty acid homeostasis modulator)
B: reactive intermediate imine deaminase a homolog (mus musculus) (aka reactive intermediate imine deaminase a homolog)
C: ras-related associated with diabetes (mus musculus) (aka ras-related associated with diabetes)
D: adipose differentiation related protein, pseudogene (mus musculus) (aka adipose differentiation related protein, pseudogene)
E: steroidogenic acute regulatory protein, mitochondrial-like (gallus gallus) (aka steroidogenic acute regulatory protein, mitochondrial-like)
F: None of the above. | F |
<Instruct>: Given the context 'Isolation and characterization of a structural homologue of human PRK2 from rat liver.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
B: pak-2 (homo sapiens) (aka protein kinase n2)
C: prkcb2 (homo sapiens) (aka protein kinase c beta)
D: prkm2 (homo sapiens) (aka mitogen-activated protein kinase 1)
E: pk2 (homo sapiens) (aka prokineticin 2)
F: None of the above. | B |
<Instruct>: Given the context 'A homologue of human protein kinase C (PKC)-related kinase-2, PRK2, which had previously escaped identification in normal mammalian tissues, was isolated from rat liver as the protease-activated kinase (PAK) originally named PAK-2.', select the correct biomedical concept corresponding to 'protein kinase c (pkc)-related kinase-2'. Answer using one of the provided options. | <Options>: A: prkcl2 (homo sapiens) (aka protein kinase n2)
B: calcium/calmodulin dependent protein kinase kinase 2 (homo sapiens) (aka calcium/calmodulin dependent protein kinase kinase 2)
C: serine/threonine-protein kinase prk-2 (caenorhabditis elegans) (aka serine/threonine-protein kinase prk-2)
D: protein kinase c;protein kinase c-like 2 (caenorhabditis elegans) (aka protein kinase c;protein kinase c-like 2)
E: protein kinase c-like 2 (xenopus tropicalis) (aka protein kinase c-like 2)
F: None of the above. | A |
<Instruct>: Given the context 'A homologue of human protein kinase C (PKC)-related kinase-2, PRK2, which had previously escaped identification in normal mammalian tissues, was isolated from rat liver as the protease-activated kinase (PAK) originally named PAK-2.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: prk2 (homo sapiens) (aka protein kinase n2)
B: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
C: pk2 (homo sapiens) (aka prokineticin 2)
D: pkk2 (homo sapiens) (aka ankyrin repeat and kinase domain containing 1)
E: pkc2 (homo sapiens) (aka protein kinase c zeta)
F: None of the above. | A |
<Instruct>: Given the context 'A homologue of human protein kinase C (PKC)-related kinase-2, PRK2, which had previously escaped identification in normal mammalian tissues, was isolated from rat liver as the protease-activated kinase (PAK) originally named PAK-2.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
B: prk2 (homo sapiens) (aka protein kinase n2)
C: pak2 (homo sapiens) (p21 (rac1) activated kinase 2 (homo sapiens)) (aka p21 (rac1) activated kinase 2)
D: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
E: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
F: None of the above. | F |
<Instruct>: Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', select the correct biomedical concept corresponding to 'pak-1'. Answer using one of the provided options. | <Options>: A: p21 (rac1) activated kinase 1 (homo sapiens) (aka p21 (rac1) activated kinase 1)
B: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
C: pak7 (homo sapiens) (aka p21 (rac1) activated kinase 5)
D: pak-5 (homo sapiens) (aka bub1b-pak6 readthrough)
E: pak-1 (homo sapiens) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', select the correct biomedical concept corresponding to 'protein kinase n'. Answer using one of the provided options. | <Options>: A: protein kinase n (drosophila melanogaster) (aka protein kinase n)
B: prkcn (homo sapiens) (aka protein kinase d3)
C: npkc-eta (homo sapiens) (aka protein kinase c eta)
D: ndpkc (homo sapiens) (aka nme/nm23 nucleoside diphosphate kinase 3)
E: pkn (homo sapiens) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', select the correct biomedical concept corresponding to 'pkn'. Answer using one of the provided options. | <Options>: A: pkn1 (homo sapiens) (aka protein kinase n1)
B: prkcn (homo sapiens) (aka protein kinase d3)
C: prkn (homo sapiens) (aka parkin rbr e3 ubiquitin protein ligase)
D: pkn (drosophila melanogaster) (protein kinase n (drosophila melanogaster)) (aka protein kinase n)
E: pkn2 (homo sapiens) (aka protein kinase n2)
F: None of the above. | F |
<Instruct>: Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', select the correct biomedical concept corresponding to '130-kda human pkc-related kinase'. Answer using one of the provided options. | <Options>: A: protein kinase n1 (homo sapiens) (aka protein kinase n1)
B: snf related kinase (homo sapiens) (aka snf related kinase)
C: p90-rsk3 (homo sapiens) (aka ribosomal protein s6 kinase a2)
D: stk7 (homo sapiens) (protein kinase n2 (homo sapiens)) (aka protein kinase n2)
E: rps6kc1 (homo sapiens) (aka ribosomal protein s6 kinase c1)
F: None of the above. | D |
<Instruct>: Given the context 'The 130-kDa cytosolic enzyme was purified to homogeneity and shown by tryptic peptide and reverse transcriptase- polymerase chain reaction (RT-PCR)-amplified rat cDNA sequence analyses to be structurally related to the 116-kDa rat hepatic PAK-1/protein kinase N (PKN) and, even more closely (95% sequence identity) to the 130-kDa human PKC-related kinase, PRK2.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: prkcb2 (homo sapiens) (aka protein kinase c beta)
B: pak-2 (homo sapiens) (aka protein kinase n2)
C: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
D: pkc2 (homo sapiens) (aka protein kinase c zeta)
E: prkg2 (homo sapiens) (aka protein kinase cgmp-dependent 2)
F: None of the above. | B |
<Instruct>: Given the context 'Rat myeloma RNA was used as the RT-PCR template because of its relative abundance in PAK-2/PRK2 mRNA compared with liver and other rat tissues.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
B: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
C: pkn2 (homo sapiens) (aka protein kinase n2)
D: pak2 (homo sapiens) (p21 (rac1) activated kinase 2 (homo sapiens)) (aka p21 (rac1) activated kinase 2)
E: pak-3beta (homo sapiens) (aka p21 (rac1) activated kinase 3)
F: None of the above. | F |
<Instruct>: Given the context 'Rat myeloma RNA was used as the RT-PCR template because of its relative abundance in PAK-2/PRK2 mRNA compared with liver and other rat tissues.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
B: pak2 (homo sapiens) (p21 (rac1) activated kinase 2 (homo sapiens)) (aka p21 (rac1) activated kinase 2)
C: pak-3beta (homo sapiens) (aka p21 (rac1) activated kinase 3)
D: pak2 (homo sapiens) (protein kinase n2 (homo sapiens)) (aka protein kinase n2)
E: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
F: None of the above. | F |
<Instruct>: Given the context 'Rat myeloma RNA was used as the RT-PCR template because of its relative abundance in PAK-2/PRK2 mRNA compared with liver and other rat tissues.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: pkn2 (homo sapiens) (aka protein kinase n2)
B: prkm2 (homo sapiens) (aka mitogen-activated protein kinase 1)
C: pk2 (homo sapiens) (aka prokineticin 2)
D: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
E: prkg2 (homo sapiens) (aka protein kinase cgmp-dependent 2)
F: None of the above. | A |
<Instruct>: Given the context 'The catalytic properties of PAK-2/PRK2 in many respects resembled those of hepatic PAK-1/PKN, but were distinguished by more favorable kinetics with several peptide substrates, and greater sensitivity to PKC pseudosubstrate and polybasic amino acid inhibitors.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
B: pak2 (homo sapiens) (protein kinase n2 (homo sapiens)) (aka protein kinase n2)
C: pak-3beta (homo sapiens) (aka p21 (rac1) activated kinase 3)
D: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
E: p21 (rac1) activated kinase 2 (homo sapiens) (aka p21 (rac1) activated kinase 2)
F: None of the above. | F |
<Instruct>: Given the context 'The catalytic properties of PAK-2/PRK2 in many respects resembled those of hepatic PAK-1/PKN, but were distinguished by more favorable kinetics with several peptide substrates, and greater sensitivity to PKC pseudosubstrate and polybasic amino acid inhibitors.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: pk2 (homo sapiens) (aka prokineticin 2)
B: prkcb2 (homo sapiens) (aka protein kinase c beta)
C: pkn2 (homo sapiens) (aka protein kinase n2)
D: pkk2 (homo sapiens) (aka ankyrin repeat and kinase domain containing 1)
E: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
F: None of the above. | C |
<Instruct>: Given the context 'The catalytic properties of PAK-2/PRK2 in many respects resembled those of hepatic PAK-1/PKN, but were distinguished by more favorable kinetics with several peptide substrates, and greater sensitivity to PKC pseudosubstrate and polybasic amino acid inhibitors.', select the correct biomedical concept corresponding to 'pak-1'. Answer using one of the provided options. | <Options>: A: pak-1 (homo sapiens) (aka protein kinase n1)
B: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
C: pak7 (homo sapiens) (aka p21 (rac1) activated kinase 5)
D: pak-2 (homo sapiens) (aka protein kinase n2)
E: pak-6 (homo sapiens) (aka bub1b-pak6 readthrough)
F: None of the above. | F |
<Instruct>: Given the context 'The catalytic properties of PAK-2/PRK2 in many respects resembled those of hepatic PAK-1/PKN, but were distinguished by more favorable kinetics with several peptide substrates, and greater sensitivity to PKC pseudosubstrate and polybasic amino acid inhibitors.', select the correct biomedical concept corresponding to 'pkn'. Answer using one of the provided options. | <Options>: A: prkcn (homo sapiens) (aka protein kinase d3)
B: prkn (bos taurus) (aka parkin rbr e3 ubiquitin protein ligase)
C: pkn-alpha (homo sapiens) (aka protein kinase n1)
D: pkn (drosophila melanogaster) (uncharacterized protein (drosophila melanogaster)) (aka uncharacterized protein)
E: pkn (mus musculus) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'PAK-2/PRK2 was also activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
B: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
C: pkn2 (homo sapiens) (aka protein kinase n2)
D: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
E: p21 (rac1) activated kinase 2 (homo sapiens) (aka p21 (rac1) activated kinase 2)
F: None of the above. | F |
<Instruct>: Given the context 'PAK-2/PRK2 was also activated by lipids, particularly cardiolipin and to a lesser extent by other acidic phospholipids and unsaturated fatty acids.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: pk2 (homo sapiens) (aka prokineticin 2)
B: prka2 (homo sapiens) (aka palm2 and akap2 fusion)
C: pkk2 (homo sapiens) (aka ankyrin repeat and kinase domain containing 1)
D: prk2 (homo sapiens) (aka protein kinase n2)
E: prkm2 (homo sapiens) (aka mitogen-activated protein kinase 1)
F: None of the above. | D |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'pak-2'. Answer using one of the provided options. | <Options>: A: pak2 (xenopus laevis) (protein kinase n2 s homeolog (xenopus laevis)) (aka protein kinase n2 s homeolog)
B: prk2 (homo sapiens) (aka protein kinase n2)
C: pak2 (homo sapiens) (p21 (rac1) activated kinase 2 (homo sapiens)) (aka p21 (rac1) activated kinase 2)
D: pak-3beta (homo sapiens) (aka p21 (rac1) activated kinase 3)
E: pak2 (drosophila melanogaster) (p21-activated kinase (drosophila melanogaster)) (aka p21-activated kinase)
F: None of the above. | F |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'prk2'. Answer using one of the provided options. | <Options>: A: pk2 (homo sapiens) (aka prokineticin 2)
B: prkg2 (homo sapiens) (aka protein kinase cgmp-dependent 2)
C: pak-2 (homo sapiens) (aka protein kinase n2)
D: prkcb2 (homo sapiens) (aka protein kinase c beta)
E: pkc2 (homo sapiens) (aka protein kinase c zeta)
F: None of the above. | C |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'pak-1'. Answer using one of the provided options. | <Options>: A: p65-pak (homo sapiens) (aka p21 (rac1) activated kinase 1)
B: pak-5 (homo sapiens) (aka bub1b-pak6 readthrough)
C: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
D: pak7 (homo sapiens) (aka p21 (rac1) activated kinase 5)
E: pak-2 (homo sapiens) (aka protein kinase n2)
F: None of the above. | F |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'pak-1'. Answer using one of the provided options. | <Options>: A: alpha-pak (homo sapiens) (aka p21 (rac1) activated kinase 1)
B: beta-pak (homo sapiens) (aka p21 (rac1) activated kinase 3)
C: pak-6 (homo sapiens) (aka bub1b-pak6 readthrough)
D: pak-2 (homo sapiens) (aka protein kinase n2)
E: pak-1 (homo sapiens) (aka protein kinase n1)
F: None of the above. | F |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'pkn'. Answer using one of the provided options. | <Options>: A: pkn2 (homo sapiens) (aka protein kinase n2)
B: prkcn (homo sapiens) (aka protein kinase d3)
C: prkn (bos taurus) (aka parkin rbr e3 ubiquitin protein ligase)
D: pkn (mus musculus) (aka protein kinase n1)
E: pkn (drosophila melanogaster) (uncharacterized protein (drosophila melanogaster)) (aka uncharacterized protein)
F: None of the above. | F |
<Instruct>: Given the context 'It was concluded that PAK-2 is the rat homologue of human PRK2, with biochemical properties distinct from although overlapping those of the PAK-1/PKN/PRK1 isoform.', select the correct biomedical concept corresponding to 'prk1'. Answer using one of the provided options. | <Options>: A: prk (homo sapiens) (aka polo like kinase 3)
B: prka1 (homo sapiens) (aka a-kinase anchoring protein 1)
C: serine/threonine protein kinase prk1 (saccharomyces cerevisiae s288c) (aka serine/threonine protein kinase prk1)
D: pkn1 (homo sapiens) (aka protein kinase n1)
E: prkaa1 (homo sapiens) (aka protein kinase amp-activated catalytic subunit alpha 1)
F: None of the above. | D |
<Instruct>: Given the context 'Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.
Dipeptidyl-peptidase I, a lysosomal cysteine proteinase, is important in intracellular degradation of proteins and appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dppii (homo sapiens) (aka dipeptidyl peptidase 7)
B: dipeptidase 1 (homo sapiens) (aka dipeptidase 1)
C: tripeptidyl peptidase 1 (homo sapiens) (aka tripeptidyl peptidase 1)
D: dipeptidyl peptidase family member 1 (caenorhabditis elegans) (aka dipeptidyl peptidase family member 1)
E: dpp1 (homo sapiens) (aka cathepsin c)
F: None of the above. | E |
<Instruct>: Given the context 'Human dipeptidyl-peptidase I. Gene characterization, localization, and expression.
Dipeptidyl-peptidase I, a lysosomal cysteine proteinase, is important in intracellular degradation of proteins and appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dipeptidyl peptidase family member 1 (caenorhabditis elegans) (aka dipeptidyl peptidase family member 1)
B: dipeptidyl peptidase 3 (homo sapiens) (aka dipeptidyl peptidase 3)
C: dipeptidase 1 (homo sapiens) (aka dipeptidase 1)
D: ii (homo sapiens) (dipeptidyl peptidase 7 (homo sapiens)) (aka dipeptidyl peptidase 7)
E: dpp-i (homo sapiens) (aka cathepsin c)
F: None of the above. | E |
<Instruct>: Given the context 'In the present investigation the gene for dipeptidyl-peptidase I was cloned and characterized.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dppii (homo sapiens) (aka dipeptidyl peptidase 7)
B: dipeptidyl peptidase family member 1 (caenorhabditis elegans) (aka dipeptidyl peptidase family member 1)
C: dipeptidyl peptidase 3 (homo sapiens) (aka dipeptidyl peptidase 3)
D: tripeptidyl peptidase 1 (homo sapiens) (aka tripeptidyl peptidase 1)
E: dpp-i (homo sapiens) (aka cathepsin c)
F: None of the above. | E |
<Instruct>: Given the context 'Northern analyses demonstrated that the dipeptidyl-peptidase I message is expressed at high levels in lung, kidney, and placenta, at moderate to low levels in many organs, and at barely detectable levels in the brain, suggesting tissue-specific regulation.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dipeptidyl peptidase family member 1 (caenorhabditis elegans) (aka dipeptidyl peptidase family member 1)
B: dipeptidyl peptidase 7 (homo sapiens) (aka dipeptidyl peptidase 7)
C: dipeptidase 1 (homo sapiens) (aka dipeptidase 1)
D: tripeptidyl peptidase 1 (homo sapiens) (aka tripeptidyl peptidase 1)
E: dpp-i (homo sapiens) (aka cathepsin c)
F: None of the above. | E |
<Instruct>: Given the context 'Treatment of lymphocytes with interleukin-2 resulted in a significant increase in dipeptidyl-peptidase I mRNA levels, suggesting that this gene is subjected to transcriptional regulation.', select the correct biomedical concept corresponding to 'interleukin-2'. Answer using one of the provided options. | <Options>: A: fgf-2 (homo sapiens) (aka fibroblast growth factor 2)
B: csf2 (homo sapiens) (aka colony stimulating factor 2)
C: il-2 (homo sapiens) (aka interleukin 2)
D: interleukin enhancer binding factor 2 (homo sapiens) (aka interleukin enhancer binding factor 2)
E: il22 (homo sapiens) (aka interleukin 22)
F: None of the above. | C |
<Instruct>: Given the context 'Treatment of lymphocytes with interleukin-2 resulted in a significant increase in dipeptidyl-peptidase I mRNA levels, suggesting that this gene is subjected to transcriptional regulation.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dpp-i (homo sapiens) (aka cathepsin c)
B: dipeptidyl peptidase 3 (homo sapiens) (aka dipeptidyl peptidase 3)
C: dppii (homo sapiens) (aka dipeptidyl peptidase 7)
D: dipeptidase 1 (homo sapiens) (aka dipeptidase 1)
E: tripeptidyl peptidase 1 (homo sapiens) (aka tripeptidyl peptidase 1)
F: None of the above. | A |
<Instruct>: Given the context 'The results provide initial insights into the molecular basis for the regulation of human dipeptidyl-peptidase I.', select the correct biomedical concept corresponding to 'dipeptidyl-peptidase i'. Answer using one of the provided options. | <Options>: A: dipeptidyl peptidase family member 1 (caenorhabditis elegans) (aka dipeptidyl peptidase family member 1)
B: dipeptidyl peptidase 3 (homo sapiens) (aka dipeptidyl peptidase 3)
C: dppii (homo sapiens) (aka dipeptidyl peptidase 7)
D: dipeptidase 1 (homo sapiens) (aka dipeptidase 1)
E: dpp1 (homo sapiens) (aka cathepsin c)
F: None of the above. | E |
<Instruct>: Given the context 'Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
', select the correct biomedical concept corresponding to 'osteoprotegerin'. Answer using one of the provided options. | <Options>: A: gitr (homo sapiens) (aka tnf receptor superfamily member 18)
B: tweakr (homo sapiens) (aka tnf receptor superfamily member 12a)
C: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
D: rankl (homo sapiens) (aka tnf superfamily member 11)
E: opg (rattus norvegicus) (aka tnf receptor superfamily member 11b)
F: None of the above. | C |
<Instruct>: Given the context 'Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
', select the correct biomedical concept corresponding to 'osteoprotegerin'. Answer using one of the provided options. | <Options>: A: rankl (homo sapiens) (aka tnf superfamily member 11)
B: gitrl (homo sapiens) (aka tnf superfamily member 18)
C: trailr-1 (homo sapiens) (aka tnf receptor superfamily member 10a)
D: gitr (homo sapiens) (aka tnf receptor superfamily member 18)
E: tweakr (homo sapiens) (aka tnf receptor superfamily member 12a)
F: None of the above. | F |
<Instruct>: Given the context 'The protein, termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily.', select the correct biomedical concept corresponding to 'osteoprotegerin'. Answer using one of the provided options. | <Options>: A: tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (mus musculus) (aka tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin))
B: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
C: rankl (homo sapiens) (aka tnf superfamily member 11)
D: gitrl (homo sapiens) (aka tnf superfamily member 18)
E: tweakr (homo sapiens) (aka tnf receptor superfamily member 12a)
F: None of the above. | B |
<Instruct>: Given the context 'The protein, termed Osteoprotegerin (OPG), is a novel member of the TNF receptor superfamily.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opgl (rattus norvegicus) (aka tnf superfamily member 11)
B: rankl (homo sapiens) (aka tnf superfamily member 11)
C: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
D: opg (homo sapiens) (basic transcription factor 3 pseudogene 11 (homo sapiens)) (aka basic transcription factor 3 pseudogene 11)
E: opgl (xenopus laevis) (tnf superfamily member 11 l homeolog (xenopus laevis)) (aka tnf superfamily member 11 l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'In vivo, hepatic expression of OPG in transgenic mice results in a profound yet nonlethal osteopetrosis, coincident with a decrease in later stages of osteoclast differentiation.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opgg (escherichia coli str. k-12 substr. mg1655) (aka osmoregulated periplasmic glucans biosynthesis protein g)
B: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b s homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b s homeolog)
C: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b l homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b l homeolog)
D: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
E: opg (rattus norvegicus) (aka tnf receptor superfamily member 11b)
F: None of the above. | D |
<Instruct>: Given the context 'These same effects are observed upon administration of recombinant OPG into normal mice.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opg (rattus norvegicus) (aka tnf receptor superfamily member 11b)
B: opgl (rattus norvegicus) (aka tnf superfamily member 11)
C: opg (homo sapiens) (basic transcription factor 3 pseudogene 11 (homo sapiens)) (aka basic transcription factor 3 pseudogene 11)
D: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b l homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b l homeolog)
E: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
F: None of the above. | E |
<Instruct>: Given the context 'In vitro, osteoclast differentiation from precursor cells is blocked in a dose-dependent manner by recombinant OPG.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opgl (xenopus laevis) (tnf superfamily member 11 l homeolog (xenopus laevis)) (aka tnf superfamily member 11 l homeolog)
B: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
C: opgg (escherichia coli str. k-12 substr. mg1655) (aka osmoregulated periplasmic glucans biosynthesis protein g)
D: opg (homo sapiens) (basic transcription factor 3 pseudogene 11 (homo sapiens)) (aka basic transcription factor 3 pseudogene 11)
E: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b l homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b l homeolog)
F: None of the above. | B |
<Instruct>: Given the context 'Furthermore, OPG blocks ovariectomy-associated bone loss in rats.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opgl (rattus norvegicus) (aka tnf superfamily member 11)
B: rankl (homo sapiens) (aka tnf superfamily member 11)
C: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
D: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b s homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b s homeolog)
E: opgg (escherichia coli str. k-12 substr. mg1655) (aka osmoregulated periplasmic glucans biosynthesis protein g)
F: None of the above. | C |
<Instruct>: Given the context 'These data show that OPG can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opgg (escherichia coli str. k-12 substr. mg1655) (aka osmoregulated periplasmic glucans biosynthesis protein g)
B: opgl (xenopus laevis) (tnf superfamily member 11 l homeolog (xenopus laevis)) (aka tnf superfamily member 11 l homeolog)
C: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
D: opgl (rattus norvegicus) (aka tnf superfamily member 11)
E: opg (homo sapiens) (basic transcription factor 3 pseudogene 11 (homo sapiens)) (aka basic transcription factor 3 pseudogene 11)
F: None of the above. | C |
<Instruct>: Given the context 'These data show that OPG can act as a soluble factor in the regulation of bone mass and imply a utility for OPG in the treatment of osteoporosis associated with increased osteoclast activity.', select the correct biomedical concept corresponding to 'opg'. Answer using one of the provided options. | <Options>: A: opg (xenopus laevis) (tumor necrosis factor receptor superfamily member 11b l homeolog (xenopus laevis)) (aka tumor necrosis factor receptor superfamily member 11b l homeolog)
B: opgl (homo sapiens) (aka tnf superfamily member 11)
C: opg (homo sapiens) (tnf receptor superfamily member 11b (homo sapiens)) (aka tnf receptor superfamily member 11b)
D: opgl (xenopus laevis) (tnf superfamily member 11 l homeolog (xenopus laevis)) (aka tnf superfamily member 11 l homeolog)
E: opgl (rattus norvegicus) (aka tnf superfamily member 11)
F: None of the above. | C |
<Instruct>: Given the context 'Isolation of a novel human cDNA (rhoHP1) homologous to rho genes.
', select the correct biomedical concept corresponding to 'rhohp1'. Answer using one of the provided options. | <Options>: A: rhohp1 (homo sapiens) (aka ras homolog family member d)
B: rho (drosophila melanogaster) (rho1 (drosophila melanogaster)) (aka rho1)
C: rho-1 (drosophila melanogaster) (aka rhomboid)
D: rhoh9 (homo sapiens) (aka ras homolog family member c)
E: rhox homeobox family member 1 (homo sapiens) (aka rhox homeobox family member 1)
F: None of the above. | A |
<Instruct>: Given the context 'In view of its degree of homology to members of the Rho family of molecules (50-54% identical amino acids, 60-63% identical nucleotides within the coding region), the predicted product was designated RhoHP1(Rho-related protein HP1).', select the correct biomedical concept corresponding to 'rhohp1'. Answer using one of the provided options. | <Options>: A: rho1 (drosophila melanogaster) (rhomboid (drosophila melanogaster)) (aka rhomboid)
B: rhpn1 (homo sapiens) (aka rhophilin rho gtpase binding protein 1)
C: rho family gtpase 1 (homo sapiens) (aka rho family gtpase 1)
D: rhohp1 (homo sapiens) (aka ras homolog family member d)
E: rhoh (homo sapiens) (aka ras homolog family member h)
F: None of the above. | D |
<Instruct>: Given the context 'In view of its degree of homology to members of the Rho family of molecules (50-54% identical amino acids, 60-63% identical nucleotides within the coding region), the predicted product was designated RhoHP1(Rho-related protein HP1).', select the correct biomedical concept corresponding to 'rhohp1'. Answer using one of the provided options. | <Options>: A: rhoh9 (homo sapiens) (aka ras homolog family member c)
B: rho family gtpase 1 (homo sapiens) (aka rho family gtpase 1)
C: rhpn1 (homo sapiens) (aka rhophilin rho gtpase binding protein 1)
D: chp/wrch rho-like protein homolog (caenorhabditis elegans) (aka chp/wrch rho-like protein homolog)
E: rhoh (homo sapiens) (aka ras homolog family member h)
F: None of the above. | F |
<Instruct>: Given the context 'In view of its degree of homology to members of the Rho family of molecules (50-54% identical amino acids, 60-63% identical nucleotides within the coding region), the predicted product was designated RhoHP1(Rho-related protein HP1).', select the correct biomedical concept corresponding to 'rho-related protein hp1'. Answer using one of the provided options. | <Options>: A: rhobp (homo sapiens) (aka rhophilin rho gtpase binding protein 2)
B: rhohp1 (homo sapiens) (aka ras homolog family member d)
C: rho family gtpase 2 (homo sapiens) (aka rho family gtpase 2)
D: rhoh9 (homo sapiens) (aka ras homolog family member c)
E: arhp (homo sapiens) (aka dentin matrix acidic phosphoprotein 1)
F: None of the above. | B |
<Instruct>: Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', select the correct biomedical concept corresponding to 'i kappa b epsilon'. Answer using one of the provided options. | <Options>: A: ikb-epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
B: nfkbie (homo sapiens) (aka nfkb inhibitor epsilon)
C: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
D: ikk-e (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
E: i-kappa-b-epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
F: None of the above. | D |
<Instruct>: Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', select the correct biomedical concept corresponding to 'rela'. Answer using one of the provided options. | <Options>: A: rela proto-oncogene, nf-kb subunit (xenopus tropicalis) (aka rela proto-oncogene, nf-kb subunit)
B: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
C: rel proto-oncogene, nf-kb subunit (homo sapiens) (aka rel proto-oncogene, nf-kb subunit)
D: v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis) (aka v-rel avian reticuloendotheliosis viral oncogene homolog)
E: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
F: None of the above. | E |
<Instruct>: Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', select the correct biomedical concept corresponding to 'crel'. Answer using one of the provided options. | <Options>: A: leucine--trna ligase, cytoplasmic-like (glycine max) (aka leucine--trna ligase, cytoplasmic-like)
B: probable catabolite repression protein crec (glycine max) (aka probable catabolite repression protein crec)
C: creg (homo sapiens) (aka cellular repressor of e1a stimulated genes 1)
D: crrl (arabidopsis thaliana) (aka chaperone dnaj-domain superfamily protein)
E: crrl (homo sapiens) (aka dickkopf wnt signaling pathway inhibitor 3)
F: None of the above. | F |
<Instruct>: Given the context 'I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.
', select the correct biomedical concept corresponding to 'nf-kappa b'. Answer using one of the provided options. | <Options>: A: nuclear factor kappa b subunit 1 (homo sapiens) (aka nuclear factor kappa b subunit 1)
B: nf-kb2 (homo sapiens) (aka nuclear factor kappa b subunit 2)
C: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
D: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
E: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
F: None of the above. | A |
<Instruct>: Given the context 'We have isolated a human cDNA which encodes a novel I kappa B family member using a yeast two-hybrid screen for proteins able to interact with the p52 subunit of the transcription factor NF-kappa B.', select the correct biomedical concept corresponding to 'nf-kappa b'. Answer using one of the provided options. | <Options>: A: nf-kappa-b1 (homo sapiens) (aka nuclear factor kappa b subunit 1)
B: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
C: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
D: nf-kb2 (homo sapiens) (aka nuclear factor kappa b subunit 2)
E: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
F: None of the above. | A |
<Instruct>: Given the context 'The protein is found in many cell types and its expression is up-regulated following NF-kappa B activation and during myelopoiesis.', select the correct biomedical concept corresponding to 'nf-kappa b'. Answer using one of the provided options. | <Options>: A: nf-kb2 (homo sapiens) (aka nuclear factor kappa b subunit 2)
B: nf-kappabeta (homo sapiens) (aka nuclear factor kappa b subunit 1)
C: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
D: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
E: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
F: None of the above. | B |
<Instruct>: Given the context 'Consistent with its proposed role as an I kappa B molecule, I kappa B-epsilon is able to inhibit NF-kappa B-directed transactivation via cytoplasmic retention of rel proteins.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: nfkb inhibitor epsilon (homo sapiens) (aka nfkb inhibitor epsilon)
B: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
C: nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
D: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
E: ikk-e (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | E |
<Instruct>: Given the context 'Consistent with its proposed role as an I kappa B molecule, I kappa B-epsilon is able to inhibit NF-kappa B-directed transactivation via cytoplasmic retention of rel proteins.', select the correct biomedical concept corresponding to 'nf-kappa b'. Answer using one of the provided options. | <Options>: A: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
B: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
C: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
D: nf-kb (homo sapiens) (aka nuclear factor kappa b subunit 1)
E: nf-kb2 (homo sapiens) (aka nuclear factor kappa b subunit 2)
F: None of the above. | D |
<Instruct>: Given the context 'I kappa B-epsilon translation initiates from an internal ATG codon to give rise to a protein of 45 kDa, which exists as multiple phosphorylated isoforms in resting cells.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
B: nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
C: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
D: nfkbie (homo sapiens) (aka nfkb inhibitor epsilon)
E: inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | E |
<Instruct>: Given the context 'I kappa B-epsilon translation initiates from an internal ATG codon to give rise to a protein of 45 kDa, which exists as multiple phosphorylated isoforms in resting cells.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
B: nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
C: ikb-epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
D: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
E: nfkb inhibitor epsilon (homo sapiens) (aka nfkb inhibitor epsilon)
F: None of the above. | F |
<Instruct>: Given the context 'Unlike the other inhibitors, it is found almost exclusively in complexes containing RelA and/or cRel.', select the correct biomedical concept corresponding to 'rela'. Answer using one of the provided options. | <Options>: A: rela proto-oncogene, nf-kb subunit (xenopus tropicalis) (aka rela proto-oncogene, nf-kb subunit)
B: rel proto-oncogene, nf-kb subunit (homo sapiens) (aka rel proto-oncogene, nf-kb subunit)
C: rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens) (aka rela proto-oncogene, nf-kb subunit pseudogene)
D: rela (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
E: v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis) (aka v-rel avian reticuloendotheliosis viral oncogene homolog)
F: None of the above. | D |
<Instruct>: Given the context 'Unlike the other inhibitors, it is found almost exclusively in complexes containing RelA and/or cRel.', select the correct biomedical concept corresponding to 'crel'. Answer using one of the provided options. | <Options>: A: cation transport regulator-like protein 2-like (glycine max) (aka cation transport regulator-like protein 2-like)
B: creg (homo sapiens) (aka cellular repressor of e1a stimulated genes 1)
C: light-regulated protein-like (glycine max) (aka light-regulated protein-like)
D: crep (homo sapiens) (aka protein phosphatase 1 regulatory subunit 15b)
E: crrl (homo sapiens) (aka dickkopf wnt signaling pathway inhibitor 3)
F: None of the above. | F |
<Instruct>: Given the context 'Upon activation, I kappa B-epsilon protein is degraded with slow kinetics by a proteasome-dependent mechanism.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: i-kappa-b-epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
B: inhibitor of nuclear factor kappa b kinase subunit epsilon (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
C: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
D: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
E: nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
F: None of the above. | B |
<Instruct>: Given the context 'Similarly to I kappa B-alpha', select the correct biomedical concept corresponding to 'i kappa b-alpha'. Answer using one of the provided options. | <Options>: A: ikkb (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit beta)
B: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
C: nuclear factor kappa b subunit 1 (homo sapiens) (aka nuclear factor kappa b subunit 1)
D: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
E: nfkbia (homo sapiens) (aka nfkb inhibitor alpha)
F: None of the above. | E |
<Instruct>: Given the context 'and I kappa B, I kappa B-epsilon contains multiple ankyrin repeats and two conserved serines which are necessary for signal-induced degradation of the molecule.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: nfkbie (homo sapiens) (aka nfkb inhibitor epsilon)
B: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
C: nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
D: i-kappa-b-epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
E: ikk-e (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | E |
<Instruct>: Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', select the correct biomedical concept corresponding to 'i kappa b- alpha'. Answer using one of the provided options. | <Options>: A: nfkbib (homo sapiens) (aka nfkb inhibitor beta)
B: ikkb (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit beta)
C: nfkbi (homo sapiens) (aka nfkb inhibitor alpha)
D: ikka (homo sapiens) (aka component of inhibitor of nuclear factor kappa b kinase complex)
E: nuclear factor kappa b subunit 1 (homo sapiens) (aka nuclear factor kappa b subunit 1)
F: None of the above. | C |
<Instruct>: Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', select the correct biomedical concept corresponding to 'i kappa b-beta'. Answer using one of the provided options. | <Options>: A: nfkbi (homo sapiens) (aka nfkb inhibitor alpha)
B: nuclear factor kappa b subunit 2 (homo sapiens) (aka nuclear factor kappa b subunit 2)
C: nfi-b (homo sapiens) (aka nuclear factor i b)
D: nfkb inhibitor beta (homo sapiens) (aka nfkb inhibitor beta)
E: ikkb (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit beta)
F: None of the above. | D |
<Instruct>: Given the context 'Unlike I kappa B- alpha and I kappa B-beta, I kappa B-epsilon does not contain a C-terminal PEST-like sequence.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
B: nfkb inhibitor epsilon (homo sapiens) (aka nfkb inhibitor epsilon)
C: nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
D: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
E: ikk-e (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | E |
<Instruct>: Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', select the correct biomedical concept corresponding to 'i kappa b-epsilon'. Answer using one of the provided options. | <Options>: A: nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon (xenopus tropicalis) (aka nuclear factor of kappa light polypeptide gene enhancer in b-cells inhibitor, epsilon)
B: i-kappa-b-epsilon (mus musculus) (aka nuclear factor of kappa light polypeptide gene enhancer in b cells inhibitor, epsilon)
C: inhibitor of kappab kinase epsilon (mus musculus) (aka inhibitor of kappab kinase epsilon)
D: i-kappa-b-zeta (homo sapiens) (aka nfkb inhibitor zeta)
E: ikk-e (homo sapiens) (aka inhibitor of nuclear factor kappa b kinase subunit epsilon)
F: None of the above. | E |
<Instruct>: Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', select the correct biomedical concept corresponding to 'rela'. Answer using one of the provided options. | <Options>: A: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
B: rela proto-oncogene, nf-kb subunit (homo sapiens) (aka rela proto-oncogene, nf-kb subunit)
C: rel proto-oncogene, nf-kb subunit (homo sapiens) (aka rel proto-oncogene, nf-kb subunit)
D: rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens) (aka rela proto-oncogene, nf-kb subunit pseudogene)
E: rela proto-oncogene, nf-kb subunit (xenopus tropicalis) (aka rela proto-oncogene, nf-kb subunit)
F: None of the above. | B |
<Instruct>: Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', select the correct biomedical concept corresponding to 'rela'. Answer using one of the provided options. | <Options>: A: rel proto-oncogene, nf-kb subunit (homo sapiens) (aka rel proto-oncogene, nf-kb subunit)
B: rela proto-oncogene, nf-kb subunit (xenopus tropicalis) (aka rela proto-oncogene, nf-kb subunit)
C: v-rel avian reticuloendotheliosis viral oncogene homolog (xenopus tropicalis) (aka v-rel avian reticuloendotheliosis viral oncogene homolog)
D: rela proto-oncogene, nf-kb subunit pseudogene (homo sapiens) (aka rela proto-oncogene, nf-kb subunit pseudogene)
E: relb proto-oncogene, nf-kb subunit (homo sapiens) (aka relb proto-oncogene, nf-kb subunit)
F: None of the above. | F |
<Instruct>: Given the context 'I kappa B-epsilon would, therefore, appear to regulate a late, transient activation of a subset of genes, regulated by RelA/cRel NF-kappa B complexes, distinct from those regulated by other I kappa B proteins.', select the correct biomedical concept corresponding to 'crel'. Answer using one of the provided options. | <Options>: A: cation transport regulator-like protein 2-like (glycine max) (aka cation transport regulator-like protein 2-like)
B: creg (homo sapiens) (aka cellular repressor of e1a stimulated genes 1)
C: light-regulated protein-like (glycine max) (aka light-regulated protein-like)
D: probable catabolite repression protein crec (glycine max) (aka probable catabolite repression protein crec)
E: creld1 (oryctolagus cuniculus) (aka creld disulfide isomerase 1)
F: None of the above. | F |
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