instruction stringlengths 169 712 | input stringlengths 140 808 | response stringclasses 6 values |
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<Instruct>: Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.
', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
B: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
C: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
D: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
F: None of the above. | E |
<Instruct>: Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.
', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
B: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
C: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
D: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
E: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
F: None of the above. | B |
<Instruct>: Given the context 'cDNA cloning, expression and chromosome mapping of the human STAT4 gene: both STAT4 and STAT1 genes are mapped to 2q32.2-->q32.3.
', select the correct biomedical concept corresponding to 'stat1'. Answer using one of the provided options. | <Options>: A: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
B: signal transducer and activator of transcription 1 (homo sapiens) (aka signal transducer and activator of transcription 1)
C: stat2 (homo sapiens) (aka signal transducer and activator of transcription 2)
D: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
E: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
F: None of the above. | B |
<Instruct>: Given the context 'STAT4 is phosphorylated following interleukin (IL)-12 stimulation and is essential for IL-12 signal transduction.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
B: cis4 (homo sapiens) (aka suppressor of cytokine signaling 6)
C: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
D: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
E: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
F: None of the above. | D |
<Instruct>: Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
B: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
C: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
D: cis4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
F: None of the above. | E |
<Instruct>: Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
B: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
C: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
D: cis-4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
F: None of the above. | C |
<Instruct>: Given the context 'The human STAT4 cDNA was cloned, and both STAT4 and STAT1 genes were mapped to human chromosome bands 2q32.2-->q32.3 by fluorescence in situ hybridization.', select the correct biomedical concept corresponding to 'stat1'. Answer using one of the provided options. | <Options>: A: stat2 (homo sapiens) (aka signal transducer and activator of transcription 2)
B: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
C: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
D: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
E: signal transducer and activator of transcription 1 (homo sapiens) (aka signal transducer and activator of transcription 1)
F: None of the above. | E |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
B: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
C: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
D: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
E: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
F: None of the above. | D |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
B: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
C: stat4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
D: stat4 (bos taurus) (aka signal transducer and activator of transcription 4)
E: None of the above. | E |
<Instruct>: Given the context 'These results suggest that STAT4 and STAT1 may have arisen via a tandem gene duplication.', select the correct biomedical concept corresponding to 'stat1'. Answer using one of the provided options. | <Options>: A: signal transducer and activator of transcription 5a (homo sapiens) (aka signal transducer and activator of transcription 5a)
B: isgf-3 (homo sapiens) (signal transducer and activator of transcription 1 (homo sapiens)) (aka signal transducer and activator of transcription 1)
C: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
D: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
E: stat2 (homo sapiens) (aka signal transducer and activator of transcription 2)
F: None of the above. | B |
<Instruct>: Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', select the correct biomedical concept corresponding to 'stat1'. Answer using one of the provided options. | <Options>: A: stat91 (homo sapiens) (aka signal transducer and activator of transcription 1)
B: signal transducer and activator of transcription 4 (homo sapiens) (aka signal transducer and activator of transcription 4)
C: stat3 (homo sapiens) (aka signal transducer and activator of transcription 3)
D: signal transducer and activator of transcription 1 (xenopus tropicalis) (aka signal transducer and activator of transcription 1)
E: signal transducer and activator of transcription 2 (homo sapiens) (aka signal transducer and activator of transcription 2)
F: None of the above. | A |
<Instruct>: Given the context 'However, human STAT1 is expressed ubiquitously, whereas human STAT4 is expressed in several tissues including spleen, heart, brain, peripheral blood cells, and testis.', select the correct biomedical concept corresponding to 'stat4'. Answer using one of the provided options. | <Options>: A: il-4-statb (homo sapiens) (aka signal transducer and activator of transcription 6)
B: stat4 (homo sapiens) (aka signal transducer and activator of transcription 4)
C: signal transducer and activator of transcription 4 (bos taurus) (aka signal transducer and activator of transcription 4)
D: stati4 (homo sapiens) (aka suppressor of cytokine signaling 6)
E: signal transducer and activator of transcription 4 (xenopus tropicalis) (aka signal transducer and activator of transcription 4)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning and chromosome assignment to 1q32 of a human cDNA (RAB7L1) encoding a small GTP-binding protein, a member of the RAS superfamily.
', select the correct biomedical concept corresponding to 'rab7l1'. Answer using one of the provided options. | <Options>: A: rab7l (xenopus laevis) (aka rab29, member ras oncogene family s homeolog)
B: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
C: rab7l (xenopus tropicalis) (aka rab29, member ras oncogene family)
D: rab7, member ras oncogene family-like 1 (gallus gallus) (aka rab7, member ras oncogene family-like 1)
E: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
F: None of the above. | E |
<Instruct>: Given the context 'A full-length cDNA homologous to RAB7, a member of the RAB-related GTP-binding protein subfamily, was isolated from a human placenta cDNA library.', select the correct biomedical concept corresponding to 'rab7'. Answer using one of the provided options. | <Options>: A: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
B: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
C: rab7b (homo sapiens) (aka rab7b, member ras oncogene family)
D: rab7 (homo sapiens) (rab7a, member ras oncogene family (homo sapiens)) (aka rab7a, member ras oncogene family)
E: rab-7 (drosophila melanogaster) (aka rab7)
F: None of the above. | D |
<Instruct>: Given the context 'This cDNA, designated RAB7L1, has an open reading frame of 609 nucleotides encoding 203 amino acids.', select the correct biomedical concept corresponding to 'rab7l1'. Answer using one of the provided options. | <Options>: A: rab7, member ras oncogene family-like 1 (gallus gallus) (aka rab7, member ras oncogene family-like 1)
B: rab7l (xenopus tropicalis) (aka rab29, member ras oncogene family)
C: rab7l (homo sapiens) (aka rab29, member ras oncogene family)
D: rab7l (xenopus laevis) (aka rab29, member ras oncogene family s homeolog)
E: rab7 (xenopus laevis) (rab7a, member ras oncogene family l homeolog (xenopus laevis)) (aka rab7a, member ras oncogene family l homeolog)
F: None of the above. | C |
<Instruct>: Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', select the correct biomedical concept corresponding to 'beta-arrestin2'. Answer using one of the provided options. | <Options>: A: arrestin 2 (drosophila melanogaster) (aka arrestin 2)
B: arrestin beta 2 (bos taurus) (aka arrestin beta 2)
C: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
D: arrestin beta 2 (homo sapiens) (aka arrestin beta 2)
E: arrestin beta 1 (homo sapiens) (aka arrestin beta 1)
F: None of the above. | D |
<Instruct>: Given the context 'In this work we provide a novel approach to this problem using a beta-arrestin2/green fluorescent protein conjugate (betaarr2-GFP).', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
B: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
C: arrestin beta 2 (homo sapiens) (aka arrestin beta 2)
D: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
E: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
F: None of the above. | C |
<Instruct>: Given the context 'Confocal microscopy demonstrates the translocation of betaarr2-GFP to more than 15 different ligand-activated GPCRs.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: adrb2r (homo sapiens) (aka adrenoceptor beta 2)
B: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
C: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
D: arrb2 (rattus norvegicus) (arrestin, beta 2, pseudogene (rattus norvegicus)) (aka arrestin, beta 2, pseudogene)
E: arrb2 (homo sapiens) (aka arrestin beta 2)
F: None of the above. | E |
<Instruct>: Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
B: arr2 (homo sapiens) (aka arrestin beta 2)
C: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
D: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
E: arrestin, beta 2, pseudogene (rattus norvegicus) (aka arrestin, beta 2, pseudogene)
F: None of the above. | B |
<Instruct>: Given the context 'The use of betaarr2-GFP as a biosensor to recognize the activation of pharmacologically distinct GPCRs should accelerate the identification of orphan receptors and permit the optical study of their signal transduction biology intractable to ordinary biochemical methods.', select the correct biomedical concept corresponding to 'betaarr2'. Answer using one of the provided options. | <Options>: A: arb2 (homo sapiens) (adrenoceptor beta 2 (homo sapiens)) (aka adrenoceptor beta 2)
B: grin2b (homo sapiens) (aka glutamate ionotropic receptor nmda type subunit 2b)
C: betaarr2 (xenopus tropicalis) (aka arrestin beta 2)
D: arrestin, beta 2, pseudogene (rattus norvegicus) (aka arrestin, beta 2, pseudogene)
E: None of the above. | E |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hepatocyte growth factor activator inhibitor type 2'. Answer using one of the provided options. | <Options>: A: serine peptidase inhibitor kazal type 2 (homo sapiens) (aka serine peptidase inhibitor kazal type 2)
B: serpin family i member 2 (homo sapiens) (aka serpin family i member 2)
C: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
D: pai2 (homo sapiens) (aka serpin family b member 2)
E: serpina2 (homo sapiens) (aka serpin family a member 2 (gene/pseudogene))
F: None of the above. | C |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hepatocyte growth factor (hgf) activator'. Answer using one of the provided options. | <Options>: A: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
B: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
C: hgf activator (xenopus tropicalis) (aka hgf activator)
D: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
E: hgfa (homo sapiens) (aka hgf activator)
F: None of the above. | E |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
B: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
C: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
D: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
E: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
F: None of the above. | A |
<Instruct>: Given the context 'Purification and cloning of hepatocyte growth factor activator inhibitor type 2, a Kunitz-type serine protease inhibitor.
Hepatocyte growth factor (HGF) activator is a serine protease responsible for proteolytic activation of HGF in response to tissue injury and thus plays an important role in the regulation of biological functions of HGF in regenerating tissue.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hgf (homo sapiens) (hepatocyte growth factor (homo sapiens)) (aka hepatocyte growth factor)
B: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
C: hgf5 (homo sapiens) (aka re1 silencing transcription factor)
D: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
E: hgf2 (homo sapiens) (aka gingival fibromatosis, hereditary, 2)
F: None of the above. | A |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hgf activator (homo sapiens) (aka hgf activator)
B: hgf activator (rattus norvegicus) (aka hgf activator)
C: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
D: hgf activator (sus scrofa) (aka hgf activator)
E: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
F: None of the above. | A |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator inhibitor type 1'. Answer using one of the provided options. | <Options>: A: agti (homo sapiens) (aka agouti signaling protein)
B: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
C: antizyme inhibitor 1 (homo sapiens) (aka antizyme inhibitor 1)
D: pai-1 (homo sapiens) (aka serpin family e member 1)
E: hypoxia inducible factor 1 subunit alpha inhibitor (homo sapiens) (aka hypoxia inducible factor 1 subunit alpha inhibitor)
F: None of the above. | B |
<Instruct>: Given the context 'We previously purified an inhibitor of HGF activator (HGF activator inhibitor type 1, HAI-1) from the conditioned medium of a human stomach carcinoma cell line MKN45 and cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
B: hai2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
D: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
E: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
F: None of the above. | A |
<Instruct>: Given the context 'HAI-1 is a novel member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: haik1 (homo sapiens) (aka keratin 23)
B: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
C: hai-1 (sus scrofa) (aka serine peptidase inhibitor, kunitz type 1)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | D |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
B: hgf activator (sus scrofa) (aka hgf activator)
C: hgf activator (homo sapiens) (aka hgf activator)
D: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
E: hgfal (homo sapiens) (aka hyaluronan binding protein 2)
F: None of the above. | C |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
C: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
D: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: serpinf2 (homo sapiens) (aka serpin family f member 2)
F: None of the above. | D |
<Instruct>: Given the context 'In the present study, we purified a second type of HGF activator inhibitor (HAI-2) from the conditioned medium of MKN45 cells and molecularly cloned its cDNA.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: itih2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
C: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: serpinf2 (homo sapiens) (aka serpin family f member 2)
F: None of the above. | F |
<Instruct>: Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
B: inter-alpha-trypsin inhibitor heavy chain 2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
C: serpinf2 (homo sapiens) (aka serpin family f member 2)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
F: None of the above. | E |
<Instruct>: Given the context 'The cDNA sequence revealed that HAI-2 is derived from a precursor protein of 252 amino acids and contains two Kunitz domains, indicating that HAI-2 is also a member of the Kunitz family of serine protease inhibitors.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
B: serpinf2 (homo sapiens) (aka serpin family f member 2)
C: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
D: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: itih2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
F: None of the above. | D |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
B: itih2 (homo sapiens) (aka inter-alpha-trypsin inhibitor heavy chain 2)
C: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
D: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
E: serpinf2 (homo sapiens) (aka serpin family f member 2)
F: None of the above. | C |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hai-1 (xenopus tropicalis) (aka serine peptidase inhibitor, kunitz type 1)
B: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
C: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
D: haik1 (homo sapiens) (aka keratin 23)
E: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
F: None of the above. | C |
<Instruct>: Given the context 'The primary translation product of HAI-2 has a hydrophobic sequence in the COOH-terminal region, suggesting that, like HAI-1, HAI-2 is produced in a membrane-associated form and secreted in a proteolytically truncated form.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
B: hai-2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
C: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
D: serpinf2 (homo sapiens) (aka serpin family f member 2)
E: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
F: None of the above. | B |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hai-2'. Answer using one of the provided options. | <Options>: A: hai1 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 1)
B: tfpi-2 (homo sapiens) (aka tissue factor pathway inhibitor 2)
C: serpinf2 (homo sapiens) (aka serpin family f member 2)
D: serine peptidase inhibitor, kunitz type 2 (homo sapiens) (aka serine peptidase inhibitor, kunitz type 2)
E: hcinf2 (homo sapiens) (aka solute carrier family 34 member 1)
F: None of the above. | D |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hai-1'. Answer using one of the provided options. | <Options>: A: hcinf1 (homo sapiens) (aka cytochrome p450 family 24 subfamily a member 1)
B: hai (homo sapiens) (serine peptidase inhibitor, kunitz type 1 (homo sapiens)) (aka serine peptidase inhibitor, kunitz type 1)
C: hait1 (homo sapiens) (aka solute carrier family 71 member 1)
D: haip1 (homo sapiens) (aka baculoviral iap repeat containing 3)
E: haik1 (homo sapiens) (aka keratin 23)
F: None of the above. | B |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hgf activator'. Answer using one of the provided options. | <Options>: A: hgf activator (sus scrofa) (aka hgf activator)
B: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
C: hgf activator (rattus norvegicus) (aka hgf activator)
D: hepatocyte growth factor activator (mus musculus) (aka hepatocyte growth factor activator)
E: hgfac (homo sapiens) (aka hgf activator)
F: None of the above. | E |
<Instruct>: Given the context 'Because HAI-2 and HAI-1 are potent inhibitors specific for HGF activator, they may be involved in regulation of proteolytic activation of HGF in injured tissues.', select the correct biomedical concept corresponding to 'hgf'. Answer using one of the provided options. | <Options>: A: hepatocyte growth factor (homo sapiens) (aka hepatocyte growth factor)
B: hgfa (homo sapiens) (aka hgf activator)
C: hgf3 (homo sapiens) (aka gingival fibromatosis, hereditary, 3)
D: hgf (homo sapiens) (interleukin 6 (homo sapiens)) (aka interleukin 6)
E: hgfl (homo sapiens) (macrophage stimulating 1 (homo sapiens)) (aka macrophage stimulating 1)
F: None of the above. | A |
<Instruct>: Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
B: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
C: glycogenin 2 (sus scrofa) (aka glycogenin 2)
D: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
E: glycogenin 2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Glycogenin-2, a novel self-glucosylating protein involved in liver glycogen biosynthesis.
', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 2 (xenopus tropicalis) (aka glycogenin 2)
B: glycogenin 2 (bos taurus) (aka glycogenin 2)
C: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
D: glycogenin 1 (homo sapiens) (aka glycogenin 1)
E: glycogenin 2 (sus scrofa) (aka glycogenin 2)
F: None of the above. | F |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogenin 1 pseudogene 2 (homo sapiens) (aka glycogenin 1 pseudogene 2)
B: glycogenin 2 (bos taurus) (aka glycogenin 2)
C: glycogenin 2 (gallus gallus) (aka glycogenin 2)
D: glycogenin 1 (homo sapiens) (aka glycogenin 1)
E: glycogenin 2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'We describe the characterization of novel forms of glycogenin, designated glycogenin-2 (GN-2), encoded by a second gene that is expressed preferentially in certain tissues, including liver, heart, and pancreas.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gng2 (homo sapiens) (aka g protein subunit gamma 2)
B: gnb2 (homo sapiens) (aka g protein subunit beta 2)
C: gn-2 (homo sapiens) (aka glycogenin 2)
D: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
E: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'glycogenin-2'. Answer using one of the provided options. | <Options>: A: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
B: glycogen synthase 2 (xenopus tropicalis) (aka glycogen synthase 2)
C: glycogenin 2 (sus scrofa) (aka glycogenin 2)
D: glycogenin 2 pseudogene 2 (homo sapiens) (aka glycogenin 2 pseudogene 2)
E: glycogenin 2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2alpha'. Answer using one of the provided options. | <Options>: A: gnat2 (homo sapiens) (aka g protein subunit alpha transducin 2)
B: gn-2 (homo sapiens) (aka glycogenin 2)
C: gnl2 (homo sapiens) (aka g protein nucleolar 2)
D: gnai2 (homo sapiens) (aka g protein subunit alpha i2)
E: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
F: None of the above. | B |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2beta'. Answer using one of the provided options. | <Options>: A: gng5b (homo sapiens) (aka g protein subunit gamma 5b)
B: gng2 (homo sapiens) (aka g protein subunit gamma 2)
C: gn2 (homo sapiens) (aka glycogenin 2)
D: gnb2 (homo sapiens) (aka g protein subunit beta 2)
E: gnat2 (homo sapiens) (aka g protein subunit alpha transducin 2)
F: None of the above. | C |
<Instruct>: Given the context 'Cloning of cDNAs encoding glycogenin-2 indicated the existence of multiple species, including three liver forms (GN-2alpha, GN-2beta, and GN-2gamma) generated in part by alternative splicing.', select the correct biomedical concept corresponding to 'gn-2gamma'. Answer using one of the provided options. | <Options>: A: guanine nucleotide-binding protein subunit gamma 2-like (glycine max) (aka guanine nucleotide-binding protein subunit gamma 2-like)
B: gnl2 (homo sapiens) (aka g protein nucleolar 2)
C: gn-2 (homo sapiens) (aka glycogenin 2)
D: guanine nucleotide binding protein (g protein), gamma 2 (xenopus tropicalis) (aka guanine nucleotide binding protein (g protein), gamma 2)
E: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
F: None of the above. | C |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gn-2 (homo sapiens) (aka glycogenin 2)
B: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
C: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
D: gnb2 (homo sapiens) (aka g protein subunit beta 2)
E: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
F: None of the above. | A |
<Instruct>: Given the context 'Overall, GN-2 has 40-45% identity to muscle glycogenin but is 72% identical over a 200-residue segment thought to contain the catalytic domain.', select the correct biomedical concept corresponding to 'muscle glycogenin'. Answer using one of the provided options. | <Options>: A: brain glycogen phosphorylase (mus musculus) (aka brain glycogen phosphorylase)
B: glycogenin 2 (homo sapiens) (aka glycogenin 2)
C: glycogenin 1 (homo sapiens) (aka glycogenin 1)
D: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
E: muscle glycogen phosphorylase (mus musculus) (aka muscle glycogen phosphorylase)
F: None of the above. | C |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gnt2 (homo sapiens) (aka alpha-1,6-mannosyl-glycoprotein 2-beta-n-acetylglucosaminyltransferase)
B: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
C: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
D: gn-2 (homo sapiens) (aka glycogenin 2)
E: gnl2 (homo sapiens) (aka g protein nucleolar 2)
F: None of the above. | D |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gng2 (homo sapiens) (aka g protein subunit gamma 2)
B: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
C: gn-2 (homo sapiens) (aka glycogenin 2)
D: gnl2 (homo sapiens) (aka g protein nucleolar 2)
E: gnb2 (homo sapiens) (aka g protein subunit beta 2)
F: None of the above. | C |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: gnp2 (homo sapiens) (aka glucosamine-6-phosphate deaminase 2)
C: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
D: gng2 (homo sapiens) (aka g protein subunit gamma 2)
E: gnl2 (homo sapiens) (aka g protein nucleolar 2)
F: None of the above. | F |
<Instruct>: Given the context 'GN-2 expressed in Escherichia coli or COS cells is active in self-glucosylation assays, and self-glucosylated GN-2 can be elongated by skeletal muscle glycogen synthase.', select the correct biomedical concept corresponding to 'skeletal muscle glycogen synthase'. Answer using one of the provided options. | <Options>: A: glycogen synthase 2 (homo sapiens) (aka glycogen synthase 2)
B: muscle glycogen phosphorylase (mus musculus) (aka muscle glycogen phosphorylase)
C: lgs (mus musculus) (glycogen synthase 2 (mus musculus)) (aka glycogen synthase 2)
D: glycogen synthase 1 (muscle) (gallus gallus) (aka glycogen synthase 1 (muscle))
E: glycogen synthase 1 (homo sapiens) (aka glycogen synthase 1)
F: None of the above. | E |
<Instruct>: Given the context 'Antibodies raised against GN-2 produced in E. coli recognized proteins of Mr approximately 66,000 present in extracts of rat liver and in cultured H4IIEC3 hepatoma cells.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
B: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
C: gnb2 (homo sapiens) (aka g protein subunit beta 2)
D: gnl2 (homo sapiens) (aka g protein nucleolar 2)
E: gn2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | E |
<Instruct>: Given the context 'In H4IIEC3 cells, most of the GN-2 was present as a free protein but some was covalently associated with glycogen fractions and was only released by treatment with alpha-amylase.', select the correct biomedical concept corresponding to 'gn-2'. Answer using one of the provided options. | <Options>: A: gng2 (homo sapiens) (aka g protein subunit gamma 2)
B: gn-2 (homo sapiens) (aka glycogenin 2)
C: gna-2 (caenorhabditis elegans) (aka glucosamine-phosphate n-acetyltransferase)
D: gngt2 (homo sapiens) (aka g protein subunit gamma transducin 2)
E: gnb2 (homo sapiens) (aka g protein subunit beta 2)
F: None of the above. | B |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept corresponding to 'muscle form of glycogenin'. Answer using one of the provided options. | <Options>: A: glycogenin 1 (homo sapiens) (aka glycogenin 1)
B: glycogenin 1 (mus musculus) (aka glycogenin 1)
C: glycogenin 2 (homo sapiens) (aka glycogenin 2)
D: glycogenin-1 (caenorhabditis elegans) (aka glycogenin-1)
E: liver glycogen phosphorylase (mus musculus) (aka liver glycogen phosphorylase)
F: None of the above. | A |
<Instruct>: Given the context 'H4IIEC3 cells also expressed the muscle form of glycogenin (glycogenin-1), which was attached to a chromatographically separable glycogen fraction.', select the correct biomedical concept corresponding to 'glycogenin-1'. Answer using one of the provided options. | <Options>: A: glycogenin 1 (rattus norvegicus) (aka glycogenin 1)
B: glycogenin 1 (mus musculus) (aka glycogenin 1)
C: glycogenin 1 (homo sapiens) (aka glycogenin 1)
D: glycogenin-1 (gallus gallus) (aka glycogenin 1)
E: glycogenin 2 (homo sapiens) (aka glycogenin 2)
F: None of the above. | C |
<Instruct>: Given the context 'hSK4, a member of a novel subfamily of calcium-activated potassium channels.
', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
B: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
C: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
D: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
E: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
F: None of the above. | E |
<Instruct>: Given the context 'The gene for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has been identified and expressed in Chinese hamster ovary cells.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
B: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
C: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
D: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
E: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
F: None of the above. | B |
<Instruct>: Given the context 'In physiological saline hSK4 generates a conductance of approximately 12 pS, a value in close agreement with that of other cloned SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: huk4 (homo sapiens) (aka phospholipase d family member 3)
B: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
C: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
D: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
E: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
F: None of the above. | C |
<Instruct>: Given the context 'Like other members of this family, the polypeptide encoded by hSK4 contains a previously unnoted leucine zipper-like domain in its C terminus of unknown function.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
B: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
C: huk4 (homo sapiens) (aka phospholipase d family member 3)
D: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
E: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
F: None of the above. | A |
<Instruct>: Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
B: serine/threonine kinase 4 (homo sapiens) (aka serine/threonine kinase 4)
C: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
D: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
E: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
F: None of the above. | D |
<Instruct>: Given the context 'hSK4 appears unique, however, in its very high affinity for Ca2+ (EC50 of 95 nM) and its predominant expression in nonexcitable tissues of adult animals.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: map4k4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase kinase 4)
B: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
C: mapkk4 (homo sapiens) (aka mitogen-activated protein kinase kinase 4)
D: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
E: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
F: None of the above. | F |
<Instruct>: Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
B: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
C: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
D: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
E: stk4 (homo sapiens) (aka serine/threonine kinase 4)
F: None of the above. | D |
<Instruct>: Given the context 'Together with the relatively low homology of hSK4 to other SK channel polypeptides (approximately 40% identical), these data suggest that hSK4 belongs to a novel subfamily of SK channels.', select the correct biomedical concept corresponding to 'hsk4'. Answer using one of the provided options. | <Options>: A: ssk4 (saccharomyces cerevisiae s288c) (aka mitogen-activated protein kinase kinase pbs2)
B: hbk4 (homo sapiens) (aka potassium voltage-gated channel subfamily a member 4)
C: hsk4 (homo sapiens) (aka potassium calcium-activated channel subfamily n member 4)
D: mekk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 4)
E: ysk4 (homo sapiens) (aka mitogen-activated protein kinase kinase kinase 19)
F: None of the above. | C |
<Instruct>: Given the context 'Human pulmonary alveolar proteinosis associated with a defect in GM-CSF/IL-3/IL-5 receptor common beta chain expression.
', select the correct biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'. Answer using one of the provided options. | <Options>: A: il5r (homo sapiens) (aka interleukin 5 receptor subunit alpha)
B: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
C: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
D: il3rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
E: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
F: None of the above. | D |
<Instruct>: Given the context 'In some cases congenital PAP is associated with hereditary surfactant protein (SP)-B deficiency.', select the correct biomedical concept corresponding to 'surfactant protein (sp)-b'. Answer using one of the provided options. | <Options>: A: sp-b (sus scrofa) (aka surfactant protein b)
B: surfactant protein b (bos taurus) (aka surfactant protein b)
C: sftp1b (homo sapiens) (surfactant protein a1 (homo sapiens)) (aka surfactant protein a1)
D: sftp1b (homo sapiens) (surfactant protein a2 (homo sapiens)) (aka surfactant protein a2)
E: surfactant protein b (homo sapiens) (aka surfactant protein b)
F: None of the above. | E |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept corresponding to 'gm-csf/il-3/il-5 receptor common beta chain'. Answer using one of the provided options. | <Options>: A: csf3r (homo sapiens) (aka colony stimulating factor 3 receptor)
B: il3rb (homo sapiens) (aka colony stimulating factor 2 receptor subunit beta)
C: colony stimulating factor 2 receptor subunit beta (sus scrofa) (aka colony stimulating factor 2 receptor subunit beta)
D: colony stimulating factor 2 receptor subunit beta (bos taurus) (aka colony stimulating factor 2 receptor subunit beta)
E: interleukin 2 receptor subunit beta (homo sapiens) (aka interleukin 2 receptor subunit beta)
F: None of the above. | B |
<Instruct>: Given the context 'In mice, PAP has been generated by targeted deletion of the genes for either the GM-CSF/IL-3/IL-5 receptor common beta chain (beta c) or GM-CSF.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
B: casein beta (homo sapiens) (aka casein beta)
C: betacellulin (homo sapiens) (aka betacellulin)
D: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
E: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
F: None of the above. | F |
<Instruct>: Given the context 'Here, we describe an expression defect of beta c in three of seven pediatric patients with PAP and in one patient with severe lung disease suspected to be PAP.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
B: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
C: casein beta (homo sapiens) (aka casein beta)
D: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
E: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
F: None of the above. | F |
<Instruct>: Given the context 'The patients failed to express normal levels of beta c as shown by flow cytometry.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
B: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
C: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
D: casein beta (homo sapiens) (aka casein beta)
E: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
F: None of the above. | F |
<Instruct>: Given the context 'Strikingly reduced or absent function of beta c was demonstrated by ligand binding studies and progenitor clonogenic assays.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
B: beta3b (homo sapiens) (aka basic helix-loop-helix family member e23)
C: betacellulin (homo sapiens) (aka betacellulin)
D: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
E: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
F: None of the above. | F |
<Instruct>: Given the context 'Analysis of beta c DNA revealed a point mutation from proline to threonine at codon 602 in one patient.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
B: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
C: inhibin subunit beta c (homo sapiens) (aka inhibin subunit beta c)
D: betacellulin (homo sapiens) (aka betacellulin)
E: beta3 (homo sapiens) (aka basic helix-loop-helix family member e22)
F: None of the above. | F |
<Instruct>: Given the context 'Analysis of beta c DNA revealed a point mutation from proline to threonine at codon 602 in one patient.', select the correct biomedical concept corresponding to 'beta c'. Answer using one of the provided options. | <Options>: A: propionyl-coa carboxylase subunit beta (homo sapiens) (aka propionyl-coa carboxylase subunit beta)
B: g protein subunit beta 3 (homo sapiens) (aka g protein subunit beta 3)
C: beta-3 (homo sapiens) (aka eukaryotic translation elongation factor 1 beta 2 pseudogene 2)
D: beta-5 (homo sapiens) (aka tubulin beta 4a class iva)
E: betan (homo sapiens) (aka dna polymerase lambda)
F: None of the above. | F |
<Instruct>: Given the context 'Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase.
', select the correct biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (rattus norvegicus) (aka quinolinate phosphoribosyltransferase)
C: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
D: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (mus musculus) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | A |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept corresponding to 'quinolinate phosphoribosyltransferase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
C: quinolinate phosphoribosyltransferase (mus musculus) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (bos taurus) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | D |
<Instruct>: Given the context 'Mammalian quinolinate phosphoribosyltransferase (QPRTase) (EC 2.4.2.19) is a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide (NAD) pathway.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
B: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
C: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
E: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
F: None of the above. | C |
<Instruct>: Given the context 'As the first step to elucidate molecular basis underlying the quinolinate metabolism, the cDNA encoding human brain QPRTase was cloned and characterized.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
C: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
D: qprt (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | A |
<Instruct>: Given the context 'Utilizing partial amino acid sequences obtained from highly purified porcine kidney QPRTase, a human isolog was obtained from a human brain cDNA library.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
B: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
C: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
E: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | E |
<Instruct>: Given the context 'To confirm that the cDNA clone encodes human QPRTase, its functional expression was studied in a bacterial host.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
B: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
C: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
D: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
F: None of the above. | A |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
B: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
C: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
D: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
F: None of the above. | E |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'nadc'. Answer using one of the provided options. | <Options>: A: nadc (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: nadc-1 (homo sapiens) (aka solute carrier family 13 member 2)
C: nadc3 (homo sapiens) (aka solute carrier family 13 member 3)
D: nadc-1 (oryctolagus cuniculus) (aka solute carrier family 13 member 2)
E: nad1 (saccharomyces cerevisiae s288c) (aka 40s ribosomal protein rack1 asc1)
F: None of the above. | A |
<Instruct>: Given the context 'Introduction of the human cDNA into a QPRTase defective (nadC) E. coli strain brought about an abrupt increase in QPRTase activity and allowed the cells to grow in the absence of nicotinic acid.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
B: glnq (escherichia coli str. k-12 substr. mg1655) (aka l-glutamine abc transporter atp binding subunit)
C: quinolinate phosphoribosyltransferase (homo sapiens) (aka quinolinate phosphoribosyltransferase)
D: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
E: quinolinate phosphoribosyltransferase (xenopus tropicalis) (aka quinolinate phosphoribosyltransferase)
F: None of the above. | C |
<Instruct>: Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprt (homo sapiens) (aka quinolinate phosphoribosyltransferase)
B: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
C: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
D: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
E: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
F: None of the above. | A |
<Instruct>: Given the context 'It is concluded that the cloned cDNA encodes human QPRTase which is functional beyond the phylogenic boundary.', select the correct biomedical concept corresponding to 'qprtase'. Answer using one of the provided options. | <Options>: A: qprt (xenopus laevis) (aka quinolinate phosphoribosyltransferase l homeolog)
B: quinolinate phosphoribosyltransferase (sus scrofa) (aka quinolinate phosphoribosyltransferase)
C: qprtase (mus musculus) (aka quinolinate phosphoribosyltransferase)
D: quinolinate phosphoribosyltransferase (decarboxylating) (escherichia coli str. k-12 substr. mg1655) (aka quinolinate phosphoribosyltransferase (decarboxylating))
E: prophage antitermination protein q homolog quud (escherichia coli str. k-12 substr. mg1655) (aka prophage antitermination protein q homolog quud)
F: None of the above. | F |
<Instruct>: Given the context 'Identification of a new tumour-associated antigen TM4SF5 and its expression in human cancer.
', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf3 (homo sapiens) (aka tetraspanin 8)
B: tm4sf6 (homo sapiens) (aka tetraspanin 6)
C: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
D: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
E: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
F: None of the above. | D |
<Instruct>: Given the context 'In a previous large-scale screening for differentially expressed genes in pancreatic cancer, a gene was identified that was highly overexpressed in pancreatic cancer encoding a novel putative tetraspan transmembrane protein highly homologous to the tumour-associated antigen L6.', select the correct biomedical concept corresponding to 'tumour-associated antigen l6'. Answer using one of the provided options. | <Options>: A: cancer/testis antigen family 47 member a6 (homo sapiens) (aka cancer/testis antigen family 47 member a6)
B: l6 (homo sapiens) (transmembrane 4 l six family member 1 (homo sapiens)) (aka transmembrane 4 l six family member 1)
C: mage family member a6 (homo sapiens) (aka mage family member a6)
D: paraneoplastic antigen-like protein 6a (homo sapiens) (aka paraneoplastic antigen-like protein 6a)
E: ribosomal protein l6 (homo sapiens) (aka ribosomal protein l6)
F: None of the above. | B |
<Instruct>: Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
B: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
C: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
D: tm4sf6 (homo sapiens) (aka tetraspanin 6)
E: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
F: None of the above. | E |
<Instruct>: Given the context 'Using a radiation hybrid panel the identified human gene named TM4SF5 (transmembrane 4 superfamily member 5) was localized to chromosome 17 in the region 17p13.3.', select the correct biomedical concept corresponding to 'transmembrane 4 superfamily member 5'. Answer using one of the provided options. | <Options>: A: tetraspanin 5 (homo sapiens) (aka tetraspanin 5)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4-a (homo sapiens) (aka tetraspanin 3)
D: transmembrane 4 l six family member 5 (sus scrofa) (aka transmembrane 4 l six family member 5)
E: tm4sf4 (homo sapiens) (aka transmembrane 4 l six family member 4)
F: None of the above. | B |
<Instruct>: Given the context 'The cloned TM4SF5 cDNA has a 32bp 5'-untranslated region (UTR), a 591bp open reading frame (ORF) and a 85bp 3'UTR.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (mus musculus) (aka transmembrane 4 superfamily member 5)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4sf3 (homo sapiens) (aka tetraspanin 8)
D: tm4sf8 (homo sapiens) (aka tetraspanin 3)
E: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
F: None of the above. | B |
<Instruct>: Given the context 'The predicted TM4SF5 protein with 197 amino acids contains three NH2-terminal hydrophobic transmembrane regions, followed by an extracellular hydrophilic domain containing two potential N-linked glycosylation sites and a COOH-terminal hydrophobic transmembrane region.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf8 (homo sapiens) (aka tetraspanin 3)
B: tm4sf (homo sapiens) (aka tetraspanin 1)
C: tm4sf5 (xenopus tropicalis) (aka transmembrane 4 l six family member 5)
D: tm4sf5 (sus scrofa) (aka transmembrane 4 l six family member 5)
E: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
F: None of the above. | E |
<Instruct>: Given the context 'These structural features are shared by the L6 antigen and a number of related cell surface proteins associated with cell growth.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: ribosomal protein l6 pseudogene 6 (homo sapiens) (aka ribosomal protein l6 pseudogene 6)
B: l6 (homo sapiens) (ribosomal protein l6 (homo sapiens)) (aka ribosomal protein l6)
C: h-l6 (homo sapiens) (aka transmembrane 4 l six family member 1)
D: l7rn6 (homo sapiens) (aka heat shock protein nuclear import factor hikeshi)
E: adhesion g protein-coupled receptor g6 (homo sapiens) (aka adhesion g protein-coupled receptor g6)
F: None of the above. | C |
<Instruct>: Given the context 'TM4SF5 was overexpressed in pancreatic cancer tissues as compared to both normal pancreas and chronic pancreatitis tissues, and was detected at high levels in other tumour tissues.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf5 (sus scrofa) (aka transmembrane 4 l six family member 5)
B: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
C: tm4sf3 (homo sapiens) (aka tetraspanin 8)
D: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
E: tm4sf8 (homo sapiens) (aka tetraspanin 3)
F: None of the above. | B |
<Instruct>: Given the context 'Although the precise function of TM4SF5 remains to be elucidated it may be useful in a clinical setting for tumour diagnosis and/or therapy.', select the correct biomedical concept corresponding to 'tm4sf5'. Answer using one of the provided options. | <Options>: A: tm4sf (homo sapiens) (aka tetraspanin 1)
B: tm4sf10 (homo sapiens) (aka transmembrane protein 47)
C: tm4sf5 (homo sapiens) (aka transmembrane 4 l six family member 5)
D: tm4sf3 (homo sapiens) (aka tetraspanin 8)
E: tm4sf6 (homo sapiens) (aka tetraspanin 6)
F: None of the above. | C |
<Instruct>: Given the context 'This hypothesis is supported by the strong homology to the L6 antigen, which has proved promising in immunological, therapeutic and diagnostic approaches.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: l6 (mus musculus) (transmembrane 4 superfamily member 1 (mus musculus)) (aka transmembrane 4 superfamily member 1)
B: ribosomal protein l6 pseudogene 6 (homo sapiens) (aka ribosomal protein l6 pseudogene 6)
C: h-l6 (homo sapiens) (aka transmembrane 4 l six family member 1)
D: ribosomal protein l6 (homo sapiens) (aka ribosomal protein l6)
E: l6 (drosophila melanogaster) (lethal (1) l6 (drosophila melanogaster)) (aka lethal (1) l6)
F: None of the above. | C |
<Instruct>: Given the context 'This hypothesis is supported by the strong homology to the L6 antigen, which has proved promising in immunological, therapeutic and diagnostic approaches.', select the correct biomedical concept corresponding to 'l6 antigen'. Answer using one of the provided options. | <Options>: A: ribosomal protein l6 pseudogene 6 (homo sapiens) (aka ribosomal protein l6 pseudogene 6)
B: l7rn6 (homo sapiens) (aka heat shock protein nuclear import factor hikeshi)
C: adhesion g protein-coupled receptor g6 (homo sapiens) (aka adhesion g protein-coupled receptor g6)
D: ribosomal protein l6 (homo sapiens) (aka ribosomal protein l6)
E: l6 (mus musculus) (transmembrane 4 superfamily member 1 (mus musculus)) (aka transmembrane 4 superfamily member 1)
F: None of the above. | F |
<Instruct>: Given the context 'Triplet repeat-containing ribosomal protein L14 gene in immortalized human endothelial cell line (t-HUE4).
', select the correct biomedical concept corresponding to 'ribosomal protein l14'. Answer using one of the provided options. | <Options>: A: 50s ribosomal protein l14 (glycine max) (aka 50s ribosomal protein l14)
B: 60s ribosomal protein l14-like (homo sapiens) (aka 60s ribosomal protein l14-like)
C: ribosomal protein l14 (homo sapiens) (aka ribosomal protein l14)
D: l14 (drosophila melanogaster) (ribosomal protein l14 (drosophila melanogaster)) (aka ribosomal protein l14)
E: mitochondrial ribosomal protein l14 (homo sapiens) (aka mitochondrial ribosomal protein l14)
F: None of the above. | C |
<Instruct>: Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', select the correct biomedical concept corresponding to 'ribosomal subunit protein l14'. Answer using one of the provided options. | <Options>: A: 50s ribosomal protein l14 (glycine max) (aka 50s ribosomal protein l14)
B: ribosomal protein l14 (mus musculus) (aka ribosomal protein l14)
C: l14 (homo sapiens) (ribosomal protein l14 (homo sapiens)) (aka ribosomal protein l14)
D: 60s ribosomal protein l14-like (homo sapiens) (aka 60s ribosomal protein l14-like)
E: ribosomal protein l14 pseudogene (homo sapiens) (aka ribosomal protein l14 pseudogene)
F: None of the above. | C |
<Instruct>: Given the context 'A cDNA encoding human 60S ribosomal subunit protein L14 (hRL14) was isolated from a human immortal endothelial cell line, t-HUE4.', select the correct biomedical concept corresponding to 'hrl14'. Answer using one of the provided options. | <Options>: A: hrl14 (homo sapiens) (aka ribosomal protein l14)
B: bcl2l14 (homo sapiens) (aka bcl2 like 14)
C: arl14 (homo sapiens) (aka arf like gtpase 14)
D: rpl14l (homo sapiens) (aka ribosomal protein l14 pseudogene 1)
E: hmgb1l14 (homo sapiens) (aka high mobility group box 1 pseudogene 14)
F: None of the above. | A |
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