instruction stringlengths 161 2.29k | input stringlengths 80 650 | response stringclasses 6 values |
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<Instruct>: Given the context 'Bacterial tolerance has been suggested as a possible basis for therapeutic failures, particularly in the treatment of infections caused by Staphylococcus aureus with defects in the production of autolysins.', select the correct biomedical concept corresponding to 'staphylococcus aureus'. Answer using one of the provided options. | <Options>: A: staphylococcus aureus col (aka staphylococcus aureus subsp. aureus col)
B: staphylococcus sp. s
C: staphylococcus aureus str. pa (aka staphylococcus aureus pa)
D: staphylococcus pyogenes aureus (aka staphylococcus aureus)
E: aurococcus (aka staphylococcus)
F: None of the above. | D |
<Instruct>: Given the context 'Lorian has also described the formation of numerous aberrant cross-walls by S. faecalis grown in the presence of subinhibitory concentrations of penicillin', select the correct biomedical concept corresponding to 's. faecalis'. Answer using one of the provided options. | <Options>: A: bacteroides faecalis
B: enterococcus gallinarum (streptococcus gallinarum) (aka enterococcus gallinarum)
C: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
D: enterocoque (aka enterococcus faecalis)
E: enterococcus coli (aka escherichia coli)
F: None of the above. | D |
<Instruct>: Given the context 'Lorian has also described the formation of numerous aberrant cross-walls by S. faecalis grown in the presence of subinhibitory concentrations of penicillin', select the correct biomedical concept corresponding to 's. faecalis'. Answer using one of the provided options. | <Options>: A: streptococcus gallinarum (aka enterococcus gallinarum)
B: streptococcus mutans
C: streptococcus cecorum (aka enterococcus cecorum)
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: bacteroides faecalis
F: None of the above. | F |
<Instruct>: Given the context 'MBCs were only slightly higher than MICs for the three S. faecium variants obtained from our patient, and they did not appear to be tolerant strains of S. faecium.', select the correct biomedical concept corresponding to 's. faecium'. Answer using one of the provided options. | <Options>: A: clostridium faecium
B: bacteroides faecium
C: enterenecus faecium (aka candidatus enterenecus faecium)
D: enterococcus florum
E: streptococcus faecium (aka enterococcus faecium)
F: None of the above. | E |
<Instruct>: Given the context 'MBCs were only slightly higher than MICs for the three S. faecium variants obtained from our patient, and they did not appear to be tolerant strains of S. faecium.', select the correct biomedical concept corresponding to 'patient'. Answer using one of the provided options. | <Options>: A: species
B: homo sapiens (human) (aka homo sapiens)
C: genus
D: goes
E: cancer
F: None of the above. | B |
<Instruct>: Given the context 'MBCs were only slightly higher than MICs for the three S. faecium variants obtained from our patient, and they did not appear to be tolerant strains of S. faecium.', select the correct biomedical concept corresponding to 's. faecium'. Answer using one of the provided options. | <Options>: A: enterococcus
B: corynebacterium faecium
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: enterococcus hirae
E: enterococcus faecium e155
F: None of the above. | C |
<Instruct>: Given the context 'Alternatively, a
'Wennersten C, Moellering RC Jr: Mechanism of resistance to penicillin-aminoglycoside synergism in Streptococcus faecium.', select the correct biomedical concept corresponding to 'streptococcus faecium'. Answer using one of the provided options. | <Options>: A: clostridium faecium
B: enterococcus plantarum
C: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
D: corynebacterium faecium
E: bacteroides faecium
F: None of the above. | C |
<Instruct>: Given the context 'In summary, our patient was treated for Streptococcusfaecium endocarditis with both ampicillin and the aminoglycoside antibiotic, tobramycin.', select the correct biomedical concept corresponding to 'patient'. Answer using one of the provided options. | <Options>: A: human (aka homo sapiens)
B: aides
C: data
D: isolate
E: other (aka unidentified)
F: None of the above. | A |
<Instruct>: Given the context 'In summary, our patient was treated for Streptococcusfaecium endocarditis with both ampicillin and the aminoglycoside antibiotic, tobramycin.', select the correct biomedical concept corresponding to 'streptococcusfaecium'. Answer using one of the provided options. | <Options>: A: streptococcus faecavium (aka candidatus streptococcus faecavium)
B: streptococcus durans (aka enterococcus durans)
C: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
D: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
E: 'staphylococcus faecalis' (aka staphylococcus faecalis)
F: None of the above. | D |
<Instruct>: Given the context 'The authors also wish to thank Dr. Howard S. Forster for referring this patient to us, Ms. Mary Murray and Deborah Beauvais for manuscript preparation, and Ms. Gertrude Barden, MT (ASCP), MHS, for technical assistance and advice in evaluation of this patient.
', select the correct biomedical concept corresponding to 'patient'. Answer using one of the provided options. | <Options>: A: probles
B: this
C: homo sapiens (human) (aka homo sapiens)
D: kingdom
E: data
F: None of the above. | C |
<Instruct>: Given the context 'The authors also wish to thank Dr. Howard S. Forster for referring this patient to us, Ms. Mary Murray and Deborah Beauvais for manuscript preparation, and Ms. Gertrude Barden, MT (ASCP), MHS, for technical assistance and advice in evaluation of this patient.
', select the correct biomedical concept corresponding to 'patient'. Answer using one of the provided options. | <Options>: A: other (aka unidentified)
B: cancer
C: proxys
D: human (aka homo sapiens)
E: suborder
F: None of the above. | D |
<Instruct>: Given the context 'Facklam RR: Recognition of group D streptococcal species of human origin by biochemical and
physiological tests.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: eutherian mammals (aka eutheria)
B: probles
C: homo sapiens (human) (aka homo sapiens)
D: birds (aka aves)
E: biota (aka cellular organisms)
F: None of the above. | C |
<Instruct>: Given the context 'Shungu DL, Cornett JB, Shockman GD: Morphological and physiological study of autolytic
defective Streptococcus faecium strains.', select the correct biomedical concept corresponding to 'streptococcus faecium'. Answer using one of the provided options. | <Options>: A: streptococcus faecalis (aka enterococcus faecalis)
B: enterococcus durans (streptococcus durans) (aka enterococcus durans)
C: brachybacterium faecium
D: enterococcus plantarum
E: enterococcus faecium (streptococcus faecium) (aka enterococcus faecium)
F: None of the above. | E |
<Instruct>: Given the context 'Shungu DL, Cornett JB, Shockman GD: Morphological and physiological study of autolytic
defective Streptococcus faecium strains.', select the correct biomedical concept corresponding to 'streptococcus faecium'. Answer using one of the provided options. | <Options>: A: streptococcus avium (aka enterococcus avium)
B: enterococcus durans (streptococcus durans) (aka enterococcus durans)
C: enterenecus faecium (aka candidatus enterenecus faecium)
D: streptococcus faecium subsp. casseliflavus (aka enterococcus casseliflavus)
E: enterococcus plantarum
F: None of the above. | F |
<Instruct>: Given the context 'Moellering RC Jr, Korzeniowski OM, Sande MA, et al: Species-specific resistance to antimicrobial
synergism in Streptococcusfaecium and Streptococcusfaecalis.', select the correct biomedical concept corresponding to 'streptococcusfaecium'. Answer using one of the provided options. | <Options>: A: enterococcus florum
B: streptococcus durans (aka enterococcus durans)
C: streptococcus faecium (aka enterococcus faecium)
D: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
E: clostridium faecium
F: None of the above. | C |
<Instruct>: Given the context 'Moellering RC Jr, Korzeniowski OM, Sande MA, et al: Species-specific resistance to antimicrobial
synergism in Streptococcusfaecium and Streptococcusfaecalis.', select the correct biomedical concept corresponding to 'streptococcusfaecalis'. Answer using one of the provided options. | <Options>: A: streptococcus faecavium (aka candidatus streptococcus faecavium)
B: bacteroides faecalis
C: staphylococcus faecalis ('staphylococcus faecalis') (aka staphylococcus faecalis)
D: streptococcus cecorum (aka enterococcus cecorum)
E: streptococcus faecalis (aka enterococcus faecalis)
F: None of the above. | E |
<Instruct>: Given the context 'Moellering RC Jr, Murray BE, Schoenbaum SC, et al: A novel mechanism of resistance to penicillin
gentamicin synergism in S. faecalis.', select the correct biomedical concept corresponding to 's. faecalis'. Answer using one of the provided options. | <Options>: A: streptococcus faecalis (aka enterococcus faecalis)
B: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
C: streptococcus faecium (aka enterococcus faecium)
D: bacteroides faecalis
E: enterococcus coli (aka escherichia coli)
F: None of the above. | A |
<Instruct>: Given the context 'Krogstad DJ, Korfhagen TR, Moellering RC Jr, et al: Aminoglycoside-inactivating enzymes in
clinical isolates of Streptococcusfaecalis: An explanation for resistance to antibiotic synergism.', select the correct biomedical concept corresponding to 'streptococcusfaecalis'. Answer using one of the provided options. | <Options>: A: streptococcus gallinarum (aka enterococcus gallinarum)
B: enterococcus faecalis (streptococcus glycerinaceus) (aka enterococcus faecalis)
C: streptococcus gallinaceus
D: enterococcus florum
E: streptococcus ovis
F: None of the above. | B |
<Instruct>: Given the context 'J Clin Invest 62:480-486, 1978
S. FAECIUM ENDOCARDITIS 249
12.', select the correct biomedical concept corresponding to 's. faecium'. Answer using one of the provided options. | <Options>: A: sphingobacterium faecium
B: brachybacterium faecium
C: enterenecus faecium (aka candidatus enterenecus faecium)
D: corynebacterium faecium
E: streptococcus faecium (aka enterococcus faecium)
F: None of the above. | E |
<Instruct>: Given the context 'Abstract
A recombinant phage, SpC3, containing a 17 kb genomic DNA insert representing approximately 60% of the 3' portion of the sheep collagen alpha 2 gene, was evaluated by electron microscopic R loop analysis.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis ovis (aka ovis aries)
B: cattle (aka bos)
C: cow (aka bos taurus) (aka bos taurus)
D: dall's sheep (aka ovis dalli)
E: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
F: None of the above. | A |
<Instruct>: Given the context 'Images
Nucleic Acids Research
Structural organization of a 17 KB segment of the a2 collagen gene: evaluation by R loop mapping Millie P.Schafer, Charles D.Boyd, Paul Tolstoshev and Ronald G.Crystal
Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20205, USA
Received 13 February 1980
ABSTRACT
A recombinant phage, SpC3, containing a 17 kb genomic DNA insert rep
resenting approximately 60% of the 3' portion of the sheep collagen a2 gene, was evaluated by electron microscopic R loop analysis.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
C: ovis orientalis aries (aka ovis aries)
D: suidae (pigs (aka suidae))
E: bovidae
F: None of the above. | C |
<Instruct>: Given the context 'The present study further characterizes this portion of the a2
gene by utilizing electron microscopic R loop analysis to map the coding regions (exons) and intervening sequences (introns) contained within the sheep genomic insert of SpC3.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cattle (aka bos)
B: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: lambs (aka ovis aries)
E: ovis dalli (dall's sheep) (aka ovis dalli)
F: None of the above. | D |
<Instruct>: Given the context 'The sheep a2 collagen recombinant clone, SpC3, containing a portion of the sheep a2 gene, was isolated as previously described (2).', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: dall sheep (aka ovis dalli)
B: suidae (pigs (aka suidae))
C: ovis sp.
D: cow (aka bos taurus) (aka bos taurus)
E: ovis aries (ovis orientalis aries) (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'The sheep a2 collagen recombinant clone, SpC3, containing a portion of the sheep a2 gene, was isolated as previously described (2).', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: lambs (aka ovis aries)
B: suidae (pigs (aka suidae))
C: cow (aka bos taurus) (aka bos taurus)
D: cattle (aka bos)
E: bovidae
F: None of the above. | A |
<Instruct>: Given the context 'The sheep a2 collagen recombinant clone, SpC3, containing a portion of the sheep a2 gene, was isolated as previously described (2).', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: suidae (pigs (aka suidae))
B: ovis
C: bovidae
D: cow (aka bos taurus) (aka bos taurus)
E: cattle (aka bos)
F: None of the above. | F |
<Instruct>: Given the context 'Briefly,
high molecular weight fetal sheep liver DNA was extracted by the method of Blin and Stafford (3), and 15-20 kb DNA fragments, resulting from partial Eco RI digestion, were isolated and ligated to the left and right arms of Charon 4A.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis
B: cow (aka bos taurus) (aka bos taurus)
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: ovis sp.
E: ovis ovis (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'The recombinant DNA was then packaged in vitro and the sheep
genomic library amplified (4-6).', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: bovidae
B: cow (aka bos taurus) (aka bos taurus)
C: ovis
D: ovis sp.
E: domestic sheep (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'Screening of the sheep genomic library was
conducted utilizing [32 P]-labeled fetal sheep tendon type I collagen cDNA and
several positive recombinant phages were isolated.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: dall's sheep (aka ovis dalli)
B: suidae (pigs (aka suidae))
C: ovis ammon aries (aka ovis aries)
D: ovis sp.
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | C |
<Instruct>: Given the context 'Screening of the sheep genomic library was
conducted utilizing [32 P]-labeled fetal sheep tendon type I collagen cDNA and
several positive recombinant phages were isolated.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cow (aka bos taurus) (aka bos taurus)
B: suidae (pigs (aka suidae))
C: ovis sp.
D: bovidae
E: lambs (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'One recombinant, containing a 17 kb sheep genomic insert, was demonstrated to have coding sequences corresponding to 60% of the 3' end of a2 mRNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cattle (aka bos)
B: ovis ammon aries (aka ovis aries)
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: cow (aka bos taurus) (aka bos taurus)
E: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
F: None of the above. | B |
<Instruct>: Given the context 'The construction and screening of the sheep genomic library together with amplification of pCg45 and preparation of high titre lysates of chimaeric
Charon 4A were performed under the physical and biological containment levels specified by the NIH guidelines for recombinant DNA research (11).
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cow (aka bos taurus) (aka bos taurus)
B: lambs (aka ovis aries)
C: ovis sp.
D: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
E: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
F: None of the above. | B |
<Instruct>: Given the context 'Hybridization of fetal sheep tendon type I collagen mRNA to SpC3 DNA
yielded a complex R loop pattern in the region where the sheep genomic insert was expected to be ligated to the arms of the lambda vector, Charon 4A.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis aries vignei (aka ovis vignei)
B: bovidae
C: ovis sp.
D: wild sheep (aka ovis aries)
E: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
F: None of the above. | D |
<Instruct>: Given the context 'Hybridization of fetal sheep tendon type I collagen mRNA to SpC3 DNA
yielded a complex R loop pattern in the region where the sheep genomic insert was expected to be ligated to the arms of the lambda vector, Charon 4A.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis dalli (dall's sheep) (aka ovis dalli)
B: cow (aka bos taurus) (aka bos taurus)
C: ovis sp.
D: wild sheep (aka ovis aries)
E: cattle (aka bos)
F: None of the above. | D |
<Instruct>: Given the context 'To
confirm that these hybridization events were restricted to the inserted sheep DNA fragment, duplex DNA strands on both sides of this hybridization area were measured.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis
B: cattle (aka bos)
C: dall sheep (aka ovis dalli)
D: suidae (pigs (aka suidae))
E: ovis ovis (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'Although, by convention, introns are usually sequentially labeled 5' to 3', an opposite order had to be employed in this case as SpC3 does not contain the sequences coding for the 5' end of sheep a2 mRNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis orientalis aries (aka ovis aries)
B: bovidae
C: ovis sp.
D: cow (aka bos taurus) (aka bos taurus)
E: suidae (pigs (aka suidae))
F: None of the above. | A |
<Instruct>: Given the context 'Although, by convention, introns are usually sequentially labeled 5' to 3', an opposite order had to be employed in this case as SpC3 does not contain the sequences coding for the 5' end of sheep a2 mRNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis dalli (dall's sheep) (aka ovis dalli)
B: ovis
C: bovidae
D: cattle (aka bos)
E: cow (aka bos taurus) (aka bos taurus)
F: None of the above. | F |
<Instruct>: Given the context 'A small non-hybridized tail was consistently found in the region where
the right arm of the phage was ligated to the sheep genomic insert (Figure 1).', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis
B: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
C: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
D: cow (aka bos taurus) (aka bos taurus)
E: domestic sheep (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'Electron microscopic visualization of all 17 introns and 18 exons
from hybrid molecules formed between recombinant clone SpC3 DNA and fetal sheep
tendon a2 mRNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: bovidae
B: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
C: sheep (aka ovis aries)
D: suidae (pigs (aka suidae))
E: ovis aries vignei (aka ovis vignei)
F: None of the above. | C |
<Instruct>: Given the context 'Electron microscopic R loop analysis
present in SpC3 DNA1.
of the sheep a2 introns
SpC3 was hybridized to sheep a2 mRNA as described in Materials and Methods; intron lengths were determined by comparison with *X-174 DNA lengths.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: domestic sheep (aka ovis aries)
B: dall's sheep (aka ovis dalli)
C: suidae (pigs (aka suidae))
D: cow (aka bos taurus) (aka bos taurus)
E: ovis sp.
F: None of the above. | A |
<Instruct>: Given the context 'Electron microscopic R loop analysis
present in SpC3 DNA1.
of the sheep a2 introns
SpC3 was hybridized to sheep a2 mRNA as described in Materials and Methods; intron lengths were determined by comparison with *X-174 DNA lengths.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: dall sheep (aka ovis dalli)
B: ovis
C: ovis sp.
D: domestic sheep (aka ovis aries)
E: ovis aries vignei (aka ovis vignei)
F: None of the above. | D |
<Instruct>: Given the context 'Electron microscopic R loop analysis of the sheep a2 exons
present in SpC3 DNA1.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
C: ovis orientalis aries (aka ovis aries)
D: cattle (aka bos)
E: suidae (pigs (aka suidae))
F: None of the above. | C |
<Instruct>: Given the context '36 q5 - _ 33 130?47 r5 r 6 78?36
SpC3 was hybridized to sheep a2 mRNA as described in M4aterials and
Methods; exon lengths were determined by comparison with pBR322 DNA lengths.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
B: bovidae
C: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
D: suidae (pigs (aka suidae))
E: lambs (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'The largest exon, "a", located on the extreme 3' end of the sheep genomic insert, contained
approximately 800 bp.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: dall sheep (aka ovis dalli)
B: ovis ovis (aka ovis aries)
C: bovidae
D: cattle (aka bos)
E: ovis
F: None of the above. | B |
<Instruct>: Given the context 'Exon "a" and exon "b", the two exons situated on either side of intron 1, coded for around 1000 bases of a2 collagen information; these two
exons contained one-third of the mapped 3,014 DNA bases complementary to a2 mRNA Length distribution and organization of the introns and exons in the sheep genomi c i nsert.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: lambs (aka ovis aries)
B: dall sheep (aka ovis dalli)
C: ovis sp.
D: cow (aka bos taurus) (aka bos taurus)
E: suidae (pigs (aka suidae))
F: None of the above. | A |
<Instruct>: Given the context 'Therefore, only 18% of the mapped 17 kb sheep genetic insert actually contained a2 structural information.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cow (aka bos taurus) (aka bos taurus)
B: ovis sp.
C: sheep (aka ovis aries)
D: ovis dalli (dall's sheep) (aka ovis dalli)
E: suidae (pigs (aka suidae))
F: None of the above. | C |
<Instruct>: Given the context 'A minimum of 17 introns interrupt the 3 kb of ca2 genetic information interspersed as 18 exons over 17 kb of sheep DNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: wild sheep (aka ovis aries)
B: bovidae
C: cow (aka bos taurus) (aka bos taurus)
D: suidae (pigs (aka suidae))
E: ovis dalli (dall's sheep) (aka ovis dalli)
F: None of the above. | A |
<Instruct>: Given the context 'A minimum of 17 introns interrupt the 3 kb of ca2 genetic information interspersed as 18 exons over 17 kb of sheep DNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: suidae (pigs (aka suidae))
B: bovidae
C: cattle (aka bos)
D: dall's sheep (aka ovis dalli)
E: ovis sp.
F: None of the above. | F |
<Instruct>: Given the context 'Although the total number of introns present within the 60% 3' portion
of the a2 sheep gene was determined to be 17, variation in the precise number
TRANSRIPTlO
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: cow (aka bos taurus) (aka bos taurus)
B: bovidae
C: domestic sheep (aka ovis aries)
D: ovis
E: dall sheep (aka ovis dalli)
F: None of the above. | C |
<Instruct>: Given the context '5.5 50 4.5 4.0 3.5 3.0 2.5 2.0 1.5 1.0
KILOBASE
Fiue3 Organization of 60% of the 3' end of the sheep a2 collagen gene.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: sheep (aka ovis aries)
B: bovidae
C: suidae (pigs (aka suidae))
D: cattle (aka bos)
E: ovis
F: None of the above. | A |
<Instruct>: Given the context 'Very small introns have been reported for tRNA genes (12,13),
and it will be necessary to sequence these regions of SpC3 to determine if such introns are present within the a2 sheep genome.
', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis nivicola (ovis canadensis nivicola) (aka ovis nivicola)
B: ovis
C: cattle (aka bos)
D: bovidae
E: ovis ovis (aka ovis aries)
F: None of the above. | E |
<Instruct>: Given the context 'The existence of mRNAs comprised of sequences complementary to noncontiguous regions in a DNA genome was first described for adenovirus (14,15) and
simian virus (16,17) genes.', select the correct biomedical concept corresponding to 'adenovirus'. Answer using one of the provided options. | <Options>: A: adenovirus sp.
B: adenovirus type 1 (aka human adenovirus 1)
C: adintoviridae
D: adeno-associated virus clade d
E: adenoviridae
F: None of the above. | E |
<Instruct>: Given the context 'The consistent appearance of a small non-hybridized tail, approximately 100 nucleotides in length, in the region where the right arm of the phage was ligated to the sheep genomic insert of SpC3 very likely corresponded to the
3' poly A sequence of the a2 mRNA.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: dall sheep (aka ovis dalli)
B: ovis aries (ovis orientalis aries) (aka ovis aries)
C: cow (aka bos taurus) (aka bos taurus)
D: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
E: suidae (pigs (aka suidae))
F: None of the above. | B |
<Instruct>: Given the context 'We are also grateful to Margery Sullivan, Laboratory of Molecular Genetics,
National Institute of Child Health and Human Development, for helpful discussions and to Dr. Helga Boedtker, Department of Chemistry, Harvard University, for making available the recombinant plasmid pCg45.
', select the correct biomedical concept corresponding to 'child'. Answer using one of the provided options. | <Options>: A: genus
B: infraclass
C: homo sapiens (human) (aka homo sapiens)
D: proeces
E: avian (aka aves)
F: None of the above. | C |
<Instruct>: Given the context 'We are also grateful to Margery Sullivan, Laboratory of Molecular Genetics,
National Institute of Child Health and Human Development, for helpful discussions and to Dr. Helga Boedtker, Department of Chemistry, Harvard University, for making available the recombinant plasmid pCg45.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: humans (aka homo)
B: placental mammals (aka eutheria)
C: human (aka homo sapiens)
D: species
E: suborder
F: None of the above. | C |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces hansenii (aka debaryomyces hansenii)
B: saccharomycotina (budding yeasts & others) (aka saccharomycotina)
C: brewer's yeast (aka saccharomyces cerevisiae)
D: saccharomyces sp.
E: saccharomyceta
F: None of the above. | C |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
B: saccharomyces hansenii (aka debaryomyces hansenii)
C: saccharomyces sp.
D: saccharomyces cerevisiae or paradoxus (aka saccharomyces cf. cerevisiae/paradoxus)
E: budding yeasts & others (aka saccharomycotina)
F: None of the above. | A |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept corresponding to 'saccharomyces cerevisiae'. Answer using one of the provided options. | <Options>: A: saccharomyces uvarum (saccharomyces bayanus var. uvarum) (aka saccharomyces uvarum)
B: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
C: saccharomyces paradoxus
D: saccharomyces cerevisiae x saccharomyces paradoxus
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | B |
<Instruct>: Given the context 'Scp160p, a multiple KH-domain protein, is a component of mRNP complexes in yeast
Abstract
Scp160p is a 160 kDa protein in the yeast Saccharomyces cerevisiae that contains 14 repeats of the hnRNP K-homology (KH) domain, and demonstrates significant sequence homology to a family of proteins collectively known as vigilins.', select the correct biomedical concept corresponding to 'saccharomyces cerevisiae'. Answer using one of the provided options. | <Options>: A: saccharomyces paradoxus
B: saccharomyces hansenii (aka debaryomyces hansenii)
C: saccharomyces cerevisiae x saccharomyces uvarum
D: saccharomyces albicans (aka candida albicans)
E: saccharomyces cerevisiae x saccharomyces paradoxus
F: None of the above. | F |
<Instruct>: Given the context 'These results demonstrate that Scp160p associates with polyribosome-bound mRNP complexes in vivo, implicating a role for this protein in one or more levels of mRNA metabolism in yeast.
', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces sp.
B: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
C: saccharomyces cerevisiae x saccharomyces mikatae
D: saccharomycotina (budding yeasts & others) (aka saccharomycotina)
E: saccharomyces hansenii (aka debaryomyces hansenii)
F: None of the above. | B |
<Instruct>: Given the context 'INTRODUCTION
Scp160p is a 1222 amino acid Saccharomyces cerevisiae protein that contains 14 copies of the hnRNP K homology (KH) domain, a highly conserved motif found in many proteins involved in RNA metabolism (1).', select the correct biomedical concept corresponding to 'saccharomyces cerevisiae'. Answer using one of the provided options. | <Options>: A: saccharomyces sp.
B: saccharomyces albicans (aka candida albicans)
C: saccharomyces globosus (aka saccharomyces uvarum)
D: saccharomyces cerevisiae x saccharomyces paradoxus
E: brewer's yeast (aka saccharomyces cerevisiae)
F: None of the above. | E |
<Instruct>: Given the context 'KH domain-containing proteins appear to have diverse functions and have been identified in all kingdoms of life, including the ribosomal protein S3 from Escherichia coli (1), Mer1p from S.cerevisiae, a meiosis-specific splicing factor (1), MEX-3 from Caenorhabditis elegans, presumably involved in mRNA localization during development (2), and FMRP, the fragile-X mental retardation protein in humans (3).', select the correct biomedical concept corresponding to 'escherichia coli'. Answer using one of the provided options. | <Options>: A: escherichia phage
B: unspecified coliform bacterium
C: escherichia coli (escherichia/shigella coli) (aka escherichia coli)
D: escherichia coli 1a
E: escherichia
F: None of the above. | C |
<Instruct>: Given the context 'KH domain-containing proteins appear to have diverse functions and have been identified in all kingdoms of life, including the ribosomal protein S3 from Escherichia coli (1), Mer1p from S.cerevisiae, a meiosis-specific splicing factor (1), MEX-3 from Caenorhabditis elegans, presumably involved in mRNA localization during development (2), and FMRP, the fragile-X mental retardation protein in humans (3).', select the correct biomedical concept corresponding to 's.cerevisiae'. Answer using one of the provided options. | <Options>: A: saccharomyces cerevisiae x saccharomyces uvarum
B: saccharomyces paradoxus
C: brewer's yeast (aka saccharomyces cerevisiae)
D: saccharomyces cerevisiae x saccharomyces paradoxus
E: saccharomyces cf. cerevisiae
F: None of the above. | C |
<Instruct>: Given the context 'KH domain-containing proteins appear to have diverse functions and have been identified in all kingdoms of life, including the ribosomal protein S3 from Escherichia coli (1), Mer1p from S.cerevisiae, a meiosis-specific splicing factor (1), MEX-3 from Caenorhabditis elegans, presumably involved in mRNA localization during development (2), and FMRP, the fragile-X mental retardation protein in humans (3).', select the correct biomedical concept corresponding to 'caenorhabditis elegans'. Answer using one of the provided options. | <Options>: A: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
B: rhabditis elegans (aka caenorhabditis elegans)
C: theocolax elegans
D: elegans subgroup (in: flies)
E: elegans subgroup (in: mosquitos)
F: None of the above. | B |
<Instruct>: Given the context 'KH domain-containing proteins appear to have diverse functions and have been identified in all kingdoms of life, including the ribosomal protein S3 from Escherichia coli (1), Mer1p from S.cerevisiae, a meiosis-specific splicing factor (1), MEX-3 from Caenorhabditis elegans, presumably involved in mRNA localization during development (2), and FMRP, the fragile-X mental retardation protein in humans (3).', select the correct biomedical concept corresponding to 'humans'. Answer using one of the provided options. | <Options>: A: humans (aka homo)
B: animals (aka metazoa)
C: macrobiotus sapiens
D: primate (aka primates)
E: homo sapiens (human) (aka homo sapiens)
F: None of the above. | E |
<Instruct>: Given the context 'Deletion of the SCP160 locus in yeast is not lethal, but results in a complex phenotype, including increased DNA content per cell, missegregation of genetic markers during sporulation, and abnormal cell morphology, including increased size and irregular shape (4).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
B: saccharomycodes
C: saccharomyces sp.
D: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
E: saccharomyces hansenii (aka debaryomyces hansenii)
F: None of the above. | A |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'chicken'. Answer using one of the provided options. | <Options>: A: arilus gallus
B: gallus gallus domesticus (aka gallus gallus)
C: turkey (aka meleagris gallopavo)
D: gallus gallus philippensis (aka gallus gallus gallus)
E: gallus
F: None of the above. | B |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: genus
C: avian (aka aves)
D: humans (aka homo)
E: placental mammals (aka eutheria)
F: None of the above. | A |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'xenopus laevis'. Answer using one of the provided options. | <Options>: A: xenopus sp. (clawed frog) (aka xenopus sp.)
B: xenopus laevis laevis (bufo laevis laevis) (aka xenopus laevis laevis)
C: platanna (aka xenopus laevis)
D: xenopus (aka xenopus <genus>)
E: xenopus borealis (xenopus laevis borealis) (aka xenopus borealis)
F: None of the above. | C |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'xenopus laevis'. Answer using one of the provided options. | <Options>: A: xenopus <genus> (xenopus) (aka xenopus <genus>)
B: anabolia laevis
C: xenopus tropicalis x xenopus laevis
D: xenopus laevis laevis (bufo laevis laevis) (aka xenopus laevis laevis)
E: xenopus borealis (xenopus laevis borealis) (aka xenopus borealis)
F: None of the above. | F |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'drosophila melanogaster'. Answer using one of the provided options. | <Options>: A: melanogaster group
B: drosophila <basidiomycete fungi> (drosophila) (aka drosophila <basidiomycete fungi>)
C: flies (aka diptera)
D: drosophila melanogaster (sophophora melanogaster) (aka drosophila melanogaster)
E: bactrocera melanogaster (bactrocera (bactrocera) melanogaster) (aka bactrocera melanogaster)
F: None of the above. | D |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'c.elegans'. Answer using one of the provided options. | <Options>: A: elegans subgroup (in: flies)
B: myzomyia elegans (aka anopheles elegans)
C: caenorhabditis sp.
D: bactris elegans
E: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
F: None of the above. | E |
<Instruct>: Given the context 'First identified in chicken, vigilin homologues have now been found in human (6), Xenopus laevis (7), Drosophila melanogaster (8), C.elegans (5) and Schizosaccharomyces pombe.', select the correct biomedical concept corresponding to 'schizosaccharomyces pombe'. Answer using one of the provided options. | <Options>: A: schizosaccharomyces japonicus (schizosaccharomyces japonicus var. versatilis) (aka schizosaccharomyces japonicus)
B: zygosaccharomyces sp.
C: schizosaccharomyces pombe (schizosaccharomyces malidevorans) (aka schizosaccharomyces pombe)
D: schizosaccharomyces pombe oy26
E: zygosaccharomyces
F: None of the above. | C |
<Instruct>: Given the context 'For example, Kruse and colleagues reported from their work with human cells in culture that vigilin may be involved in the binding and transport of tRNA (9–11).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: primate (aka primates)
B: macrobiotus sapiens
C: homo sapiens (human) (aka homo sapiens)
D: genus
E: mammals (aka mammalia)
F: None of the above. | C |
<Instruct>: Given the context 'The goal of the present study was to begin elucidating the function of Scp160p in yeast by characterizing the subcellular distribution and macromolecular interactions of this protein.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
B: saccharomyceta
C: saccharomyces cerevisiae x saccharomyces mikatae
D: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | D |
<Instruct>: Given the context 'These results indicate a role for Scp160p in mRNA metabolism in yeast, and by extension, support results seen with Xenopus vigilin in its interactions with mRNA.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces cf. cerevisiae/paradoxus (saccharomyces cerevisiae or paradoxus) (aka saccharomyces cf. cerevisiae/paradoxus)
B: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
C: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
D: saccharomyces cerevisiae x saccharomyces mikatae
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | C |
<Instruct>: Given the context 'To our knowledge, the data reported here demonstrate Scp160p to be the first example of a KH-domain protein that functions as a component of polyribosome-associated mRNP complexes in the yeast, S.cerevisiae.
MATERIALS AND METHODS
Plasmids, yeast strains and culture conditions
All recombinant DNA manipulations were performed according to standard techniques and utilized E.coli strain XL1-Blue (Stratagene).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: candida/saccharomycetales (aka candida/saccharomycales clade)
B: saccharomyces cf. cerevisiae
C: saccharomyces cerevisiae or paradoxus (aka saccharomyces cf. cerevisiae/paradoxus)
D: mycoderma cerevisiae (aka saccharomyces cerevisiae)
E: saccharomyces hansenii (aka debaryomyces hansenii)
F: None of the above. | D |
<Instruct>: Given the context 'To our knowledge, the data reported here demonstrate Scp160p to be the first example of a KH-domain protein that functions as a component of polyribosome-associated mRNP complexes in the yeast, S.cerevisiae.
MATERIALS AND METHODS
Plasmids, yeast strains and culture conditions
All recombinant DNA manipulations were performed according to standard techniques and utilized E.coli strain XL1-Blue (Stratagene).', select the correct biomedical concept corresponding to 's.cerevisiae'. Answer using one of the provided options. | <Options>: A: baker's yeast (aka saccharomyces cerevisiae)
B: saccharomyces paradoxus
C: true yeasts (aka saccharomycotina)
D: saccharomyces cerevisiae x saccharomyces uvarum
E: saccharomyceta
F: None of the above. | A |
<Instruct>: Given the context 'To our knowledge, the data reported here demonstrate Scp160p to be the first example of a KH-domain protein that functions as a component of polyribosome-associated mRNP complexes in the yeast, S.cerevisiae.
MATERIALS AND METHODS
Plasmids, yeast strains and culture conditions
All recombinant DNA manipulations were performed according to standard techniques and utilized E.coli strain XL1-Blue (Stratagene).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
B: saccharomyces cerevisiae x saccharomyces mikatae
C: saccharomyces sp.
D: mycoderma cerevisiae (aka saccharomyces cerevisiae)
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | D |
<Instruct>: Given the context 'To our knowledge, the data reported here demonstrate Scp160p to be the first example of a KH-domain protein that functions as a component of polyribosome-associated mRNP complexes in the yeast, S.cerevisiae.
MATERIALS AND METHODS
Plasmids, yeast strains and culture conditions
All recombinant DNA manipulations were performed according to standard techniques and utilized E.coli strain XL1-Blue (Stratagene).', select the correct biomedical concept corresponding to 'e.coli'. Answer using one of the provided options. | <Options>: A: escherichia phage
B: prokaryotes (aka bacteria)
C: escherichia coli k12 (aka escherichia coli k-12)
D: unspecified coliform bacterium
E: e. coli (aka escherichia coli)
F: None of the above. | E |
<Instruct>: Given the context 'To our knowledge, the data reported here demonstrate Scp160p to be the first example of a KH-domain protein that functions as a component of polyribosome-associated mRNP complexes in the yeast, S.cerevisiae.
MATERIALS AND METHODS
Plasmids, yeast strains and culture conditions
All recombinant DNA manipulations were performed according to standard techniques and utilized E.coli strain XL1-Blue (Stratagene).', select the correct biomedical concept corresponding to 'e.coli'. Answer using one of the provided options. | <Options>: A: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
B: escherichia phage
C: escherichia sp.
D: unspecified coliform bacterium
E: enterobacteria (aka enterobacteriaceae)
F: None of the above. | F |
<Instruct>: Given the context 'The yeast strain JFy1511, expressing FLAG–Scp160p, was derived by two-step gene replacement from strain yJJ52 (MATα gal7Δ102 ura3-52 trp1-289 ade1 lys1 leu2-3, 112; generously donated by Drs Mark Parthun and Judith Jaehning, University of Colorado Health Sciences Center), and confirmed by PCR.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyceta
B: saccharomycodes
C: saccharomyces cerevisiae x saccharomyces mikatae
D: brewer's yeast (aka saccharomyces cerevisiae)
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | D |
<Instruct>: Given the context 'The N-terminally HA-tagged allele of BFR1 was generated by PCR-amplifiction of the BFR1 locus from wild-type (W303) yeast genomic DNA using the primers BFR1HAF1 (5′-CCGCGGATCCATGTACC-CATACGACGTCCCAGACTACGCTATGTCCTCCCAAC-AACACAA-3′) and BFR1HINDR1 (5′-CCGCAAGCTTGTCG-ACTATTTCATATGCCACAGGAAACAG-3′), and subcloned into YIPlac211.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: brewer's yeast (aka saccharomyces cerevisiae)
B: saccharomyces hansenii (aka debaryomyces hansenii)
C: saccharomyces cf. cerevisiae
D: saccharomyces sp.
E: saccharomyces albicans (aka candida albicans)
F: None of the above. | A |
<Instruct>: Given the context 'Finally, the HA–BFR1 allele was substituted into the yeast genome in place of the native allele using linearization with SphI and standard two-step gene replacement techniques.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: baker's yeast (aka saccharomyces cerevisiae)
B: saccharomyces lactis (aka kluyveromyces lactis)
C: saccharomyceta
D: saccharomyces cerevisiae x saccharomyces mikatae
E: candida/saccharomycetales (aka candida/saccharomycales clade)
F: None of the above. | A |
<Instruct>: Given the context 'All yeast transformations and culture manipulations were performed according to standard protocols as described elsewhere (19).
', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: candida/saccharomycetales (aka candida/saccharomycales clade)
B: saccharomyces cf. cerevisiae
C: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
D: saccharomyceta
E: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
F: None of the above. | C |
<Instruct>: Given the context 'Confirmation of genomic integrations
All genomic integrations were confirmed by PCR amplifications from purified yeast genomic DNA.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces sp.
B: budding yeasts & others (aka saccharomycotina)
C: saccharomyces cerevisiae x saccharomyces mikatae
D: mycoderma cerevisiae (aka saccharomyces cerevisiae)
E: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
F: None of the above. | D |
<Instruct>: Given the context 'In brief, a 100 ml culture of yeast was grown in either YEPD or Hartwell synthetic medium, to early-log phase (OD600 = 1.0), at which time cyclohexamide (Sigma) was added directly to the culture to a final concentration of 100 µg/ml.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomycodes
B: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
C: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
D: true yeasts (aka saccharomycotina)
E: saccharomyces cf. cerevisiae
F: None of the above. | B |
<Instruct>: Given the context 'The column had been calibrated previously using the following molecular weight standards (Sigma): blue dextran (2000 kDa), thyroglobulin (669 kDa), apoferritin (443 kDa), alcohol dehydrogenase (150 kDa), and bovine serum albumin (66 kDa).', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: cattle (aka bos)
B: domestic cow (aka bos taurus)
C: bos taurus indicus (aka bos indicus)
D: bos taurus x bos indicus (aka bos indicus x bos taurus)
E: bovinae
F: None of the above. | B |
<Instruct>: Given the context 'Yeast were lysed as described for polyribosome analysis, with an additional clarification by passage through a 0.2 µm syringe-tip filter (Acrodisc) and run over the column at a rate of 0.5 ml/min in polyribosome lysis buffer following treatment with the indicated reagents.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces sp.
B: saccharomyces cerevisiae x saccharomyces mikatae
C: candida/saccharomycetales (aka candida/saccharomycales clade)
D: saccharomyces albicans (aka candida albicans)
E: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
F: None of the above. | E |
<Instruct>: Given the context 'α-FLAG affinity chromatography
For most experiments, one liter yeast cultures were grown to early log-phase and harvested by centrifugation.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces lactis (aka kluyveromyces lactis)
B: mycoderma cerevisiae (aka saccharomyces cerevisiae)
C: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
D: saccharomyces sp.
E: saccharomyces albicans (aka candida albicans)
F: None of the above. | B |
<Instruct>: Given the context 'FLAG–Scp160p fusion protein was detected by incubation of the filter with mouse M2 anti-FLAG monoclonal antibody (10 µg/ml final concentration), followed by HRP-conjugated sheep anti-mouse secondary antibody (Amersham), diluted 1:5000 as per the manufacturer’s instructions, and ECL reagent (Amersham), followed by exposure to X-ray film.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: house mouse (aka mus musculus)
C: mus cricetus (aka cricetus cricetus)
D: peromyscus
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | B |
<Instruct>: Given the context 'FLAG–Scp160p fusion protein was detected by incubation of the filter with mouse M2 anti-FLAG monoclonal antibody (10 µg/ml final concentration), followed by HRP-conjugated sheep anti-mouse secondary antibody (Amersham), diluted 1:5000 as per the manufacturer’s instructions, and ECL reagent (Amersham), followed by exposure to X-ray film.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mice (aka mus sp.) (aka mus sp.)
C: peromyscus
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | F |
<Instruct>: Given the context 'FLAG–Scp160p fusion protein was detected by incubation of the filter with mouse M2 anti-FLAG monoclonal antibody (10 µg/ml final concentration), followed by HRP-conjugated sheep anti-mouse secondary antibody (Amersham), diluted 1:5000 as per the manufacturer’s instructions, and ECL reagent (Amersham), followed by exposure to X-ray film.', select the correct biomedical concept corresponding to 'sheep'. Answer using one of the provided options. | <Options>: A: ovis vignei (ovis orientalis vignei) (aka ovis vignei)
B: ovis orientalis aries (aka ovis aries)
C: cattle (aka bos)
D: suidae (pigs (aka suidae))
E: bovidae
F: None of the above. | B |
<Instruct>: Given the context 'FLAG–Scp160p fusion protein was detected by incubation of the filter with mouse M2 anti-FLAG monoclonal antibody (10 µg/ml final concentration), followed by HRP-conjugated sheep anti-mouse secondary antibody (Amersham), diluted 1:5000 as per the manufacturer’s instructions, and ECL reagent (Amersham), followed by exposure to X-ray film.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus molossinus (aka mus musculus molossinus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | A |
<Instruct>: Given the context 'By performing a standard analysis using bovine serum albumin, the stain was able to detect ~15 ng total protein per lane.
', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos taurus indicus (aka bos indicus)
B: bos (cattle) (aka bos)
C: domestic cow (aka bos taurus)
D: bos sp.
E: bovinae
F: None of the above. | C |
<Instruct>: Given the context 'RESULTS
Expression of tagged Scp160p in yeast
An N-terminal FLAG-tagged form of Scp160p was created to facilitate detection of the protein in cells and extracts (Fig. 1A).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces hansenii (aka debaryomyces hansenii)
B: saccharomyces albicans (aka candida albicans)
C: baker's yeast (aka saccharomyces cerevisiae)
D: true yeasts (aka saccharomycotina)
E: saccharomyces cf. cerevisiae
F: None of the above. | C |
<Instruct>: Given the context 'To probe functionality of this fusion protein, we used two-step gene replacement (18) to substitute the modified allele into the SCP160 locus of haploid yeast, and then tested the morphological phenotype of the resultant cells.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces cerevisiae or paradoxus (aka saccharomyces cf. cerevisiae/paradoxus)
B: saccharomyces lactis (aka kluyveromyces lactis)
C: saccharomyces cerevisiae x saccharomyces mikatae
D: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
E: saccharomyces sp.
F: None of the above. | D |
<Instruct>: Given the context 'In all cases, yeast expressing tagged Scp160p in place of the native protein appeared indistinguishable from the corresponding wild-type strains (data not shown).', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomycodes
B: brewer's yeast (aka saccharomyces cerevisiae)
C: saccharomyces sp.
D: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
E: saccharomyces lactis (aka kluyveromyces lactis)
F: None of the above. | B |
<Instruct>: Given the context 'As a negative control, we also deleted almost the entire SCP160 coding region from the genomes of these yeast strains (Fig. 1A), and confirmed the expected mutant phenotype (data not shown).
', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces lactis (aka kluyveromyces lactis)
B: mycoderma cerevisiae (aka saccharomyces cerevisiae)
C: saccharomyceta
D: candida/saccharomycetales (aka candida/saccharomycales clade)
E: saccharomyces cerevisiae x saccharomyces mikatae
F: None of the above. | B |
<Instruct>: Given the context 'Scp160p associates with polyribosomes
To test the hypothesis that Scp160p associates with polyribosomes we used sucrose gradient ultracentrifugation to size-fractionate subcellular components of lysates prepared from yeast expressing the N-terminal FLAG-tagged Scp160p protein.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: mycoderma cerevisiae (aka saccharomyces cerevisiae)
B: budding yeasts & others (aka saccharomycotina)
C: saccharomyces cerevisiae or paradoxus (aka saccharomyces cf. cerevisiae/paradoxus)
D: saccharomyces cf. cerevisiae
E: saccharomyces sp.
F: None of the above. | A |
<Instruct>: Given the context 'A convenient internal control for these gradients was provided by an unknown endogenous yeast cross-reacting protein at ~100 kDa, that exemplified the migration pattern of a free protein, appearing only in the upper fractions of the gradient (Fig.', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces sp.
B: saccharomyces cf. cerevisiae
C: saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883 (aka saccharomyces cerevisiae)
D: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
E: saccharomyces albicans (aka candida albicans)
F: None of the above. | C |
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