instruction stringlengths 161 2.29k | input stringlengths 80 650 | response stringclasses 6 values |
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<Instruct>: Given the context 'Indeed, Eide and Anderson (7) showed that tandemly repeated duplications in the unc-54 gene of C. elegans revert at high frequencies.', select the correct biomedical concept corresponding to 'c. elegans'. Answer using one of the provided options. | <Options>: A: caenorhabditis vulgaris (aka caenorhabditis remanei)
B: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
C: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
D: bactris elegans
E: elegans subgroup (in: mosquitos)
F: None of the above. | B |
<Instruct>: Given the context 'A more likely explanation for the monomorphic nature of the sequences detected with 33.6 and (AGC)n in C. elegans is selection against sequence variants at these loci.', select the correct biomedical concept corresponding to 'c. elegans'. Answer using one of the provided options. | <Options>: A: urocitellus elegans elegans (spermophilus elegans elegans) (aka urocitellus elegans elegans)
B: bactris elegans
C: caenorhabditis sp.
D: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
E: cyclostrongylus elegans
F: None of the above. | D |
<Instruct>: Given the context 'An important step in understanding this phenomenon will therefore be the isolation and analysis of individual homologous minisatellite and simple sequence loci from a genomic library of C. elegans.
', select the correct biomedical concept corresponding to 'c. elegans'. Answer using one of the provided options. | <Options>: A: drosophila elegans
B: caenorhabditis
C: caenorhabditis elegans (rhabditis elegans) (aka caenorhabditis elegans)
D: uronema elegans
E: caromyxa elegans (aka mutinus elegans)
F: None of the above. | C |
<Instruct>: Given the context 'In the second study, adult (3–6 m) BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus cricetus (aka cricetus cricetus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'In the second study, adult (3–6 m) BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus sp. (mice (aka mus sp.))
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: peromyscus
F: None of the above. | F |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus <genus> (mice (aka mus <genus>))
C: mus cricetus (aka cricetus cricetus)
D: mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | D |
<Instruct>: Given the context 'On the third day, mice were also injected (i.p.) with saline or Escherichia coli LPS (0.33 mg/kg) and behavior (i.e., sickness and anhedonia) and markers of neuroinflammation (i.e., microglia activation and inflammatory cytokines) were determined.', select the correct biomedical concept corresponding to 'escherichia coli'. Answer using one of the provided options. | <Options>: A: enterococcus coli (aka escherichia coli)
B: enterobacteria (aka enterobacteriaceae)
C: 'escherichia faecalis' (aka escherichia faecalis)
D: escherichia phage
E: escherichia coli 1a
F: None of the above. | A |
<Instruct>: Given the context 'In the final study, adult and aged BALB/c mice were treated with the same minocycline and LPS injection regimen and markers of neuroinflammation were determined.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus sp. (mice (aka mus sp.))
D: mouse (aka mus musculus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | D |
<Instruct>: Given the context 'Moreover, minocycline facilitated the recovery from sickness behavior (i.e., anorexia, weight loss, and social withdrawal) and prevented anhedonia in adult mice challenged with LPS.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus castaneus (aka mus musculus castaneus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | A |
<Instruct>: Given the context 'Finally, in aged mice, where exaggerated neuroinflammation was elicited by LPS, minocycline pretreatment was still effective in markedly reducing mRNA levels of IL-1β, TLR2 and IDO in the hippocampus.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mus castaneus (aka mus musculus castaneus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mice (aka mus sp.) (aka mus sp.)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Moreover, in the brain of rats, minocycline abrogates microglial expression of CD11b and MHC II through a protein kinase-c dependent mechanism [45].', select the correct biomedical concept corresponding to 'rats'. Answer using one of the provided options. | <Options>: A: rattus norvegicus albus
B: rattus pyctoris (rattus rattoides) (aka rattus pyctoris)
C: rat (aka rattus) (aka rattus)
D: rattus norvegicus (rats (aka rattus norvegicus))
E: black rat (aka rattus rattus)
F: None of the above. | D |
<Instruct>: Given the context 'Moreover, our data show that minocycline pretreatment attenuated LPS-induced weight loss, social withdrawal, and anhedonia in adult mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: eastern european house mouse (aka mus musculus musculus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | A |
<Instruct>: Given the context 'The attenuation of sickness behavior was paralleled with minocycline dependent decrease in markers of neuroinflammation (IL-1β, TLR2, and IDO) in adult and aged mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mus sp. (mice (aka mus sp.))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | A |
<Instruct>: Given the context 'Methods
Animals
Male BALB/c mice, adults (3 month old) and juvenile (3–4 week old) were purchased from Harlan (Indianapolis, IN).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mouse (aka mus musculus)
D: mus domesticus (aka mus musculus domesticus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | C |
<Instruct>: Given the context 'For age comparisons, male BALB/c mice (3–4 and 20–22 month old) were purchased from the National Institute on Aging specific pathogen free colony.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus domesticus (aka mus musculus domesticus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'For age comparisons, male BALB/c mice (3–4 and 20–22 month old) were purchased from the National Institute on Aging specific pathogen free colony.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus <genus>) (aka mus <genus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: western european house mouse (aka mus musculus domesticus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | F |
<Instruct>: Given the context 'Upon arrival, mice were individually housed in polypropylene cages and maintained at 21°C under a 12 h light: 12 h dark cycle with ad libitum access to water and rodent chow.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus castaneus (aka mus musculus castaneus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'At the end of each study, mice were examined postmortem for gross signs of disease (e.g., splenomeglia or tumors).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: peromyscus
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: house mouse (aka mus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | D |
<Instruct>: Given the context 'Data from mice determined to be unhealthy were excluded from analysis (< 5%).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus domesticus (aka mus musculus domesticus)
C: peromyscus
D: mus cricetus (aka cricetus cricetus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation and whole brains were collected.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mouse (aka mus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | A |
<Instruct>: Given the context 'Sucrose preference
To assess sucrose preference, mice were provided two solutions, water or water supplemented with 2% sucrose, in 50 ml conical tubes with stoppers fitted with ball-type sipper tubes.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus domesticus (aka mus musculus domesticus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | C |
<Instruct>: Given the context 'Prior to testing conditions, all mice were acclimated to the two bottle test choice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: peromyscus
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | A |
<Instruct>: Given the context 'All mice drank both the water and the 2% sucrose solution, but preferred drinking the sucrose over the water (data not shown).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: house mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'On the day of testing, mice were fluid and food deprived for 2 h prior to testing [50].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus castaneus (aka mus musculus castaneus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | A |
<Instruct>: Given the context 'In brief, mice were euthanized by CO2 asphyxiation and blood was collected by cardiac puncture into EDTA coated syringes.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus cricetus (aka cricetus cricetus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: house mouse (aka mus musculus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | D |
<Instruct>: Given the context 'For all mouse studies, minocycline (Sigma, St. Louis, MO) was dissolved in sterile water and sonicated to ensure complete solubilization.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: western european house mouse (aka mus musculus domesticus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus (house mouse) (aka mus musculus)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | D |
<Instruct>: Given the context 'For all mouse studies, minocycline (Sigma, St. Louis, MO) was dissolved in sterile water and sonicated to ensure complete solubilization.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mice (aka mus sp.) (aka mus sp.)
C: mouse (aka mus <genus>)
D: peromyscus
E: mus molossinus (aka mus musculus molossinus)
F: None of the above. | F |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mus sp. (mice (aka mus sp.))
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus molossinus (aka mus musculus molossinus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'In the first mouse study, adult male BALB/c mice received an intraperitoneal (i.p.) injection of vehicle or minocycline (50 mg/kg) for three consecutive days.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus castaneus (aka mus musculus castaneus)
B: mice (aka mus sp.) (aka mus sp.)
C: peromyscus
D: house mouse (aka mus musculus)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | D |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: peromyscus
C: mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | C |
<Instruct>: Given the context 'On the 3rd day, mice were also injected i.p. with saline or Escherichia coli LPS (0.33 mg/kg; serotype 0127:', select the correct biomedical concept corresponding to 'escherichia coli'. Answer using one of the provided options. | <Options>: A: enterobacteriales (aka enterobacterales)
B: unspecified coliform bacterium
C: bacteria (ex cavalier-smith 1987) (aka bacteria)
D: escherichia coli (escherichia/shigella coli) (aka escherichia coli)
E: enterobacteriaceae bacterium
F: None of the above. | D |
<Instruct>: Given the context 'The LPS dosage was selected because it elicits a proinflammatory cytokine response in the brain resulting in mild transient sickness behavior in adult mice [13,53].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mice (aka mus sp.) (aka mus sp.)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | A |
<Instruct>: Given the context 'In the second study, adult male BALB/c mice received an i.p. injection with vehicle or minocycline for three consecutive days.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: house mouse (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: mus (aka mus <genus>) (aka mus <genus>)
E: mus domesticus (aka mus musculus domesticus)
F: None of the above. | B |
<Instruct>: Given the context 'In a related, but separate study, adult mice were treated with minocycline and LPS as described and anhedonia was assessed 24–39 h following i.p. injection of saline or LPS (0.33 mg/kg) (n = 15).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
D: mus sp. (mice (aka mus sp.))
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'In the third study, adult BALB/c mice were treated with minocycline and then LPS as described.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus sp. (mice (aka mus sp.))
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus musculus (house mouse) (aka mus musculus)
E: peromyscus
F: None of the above. | D |
<Instruct>: Given the context 'Mice were euthanized by CO2 asphyxiation 4 later.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: mice (aka mus <genus>) (aka mus <genus>)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | A |
<Instruct>: Given the context 'In a final study, adult (3–4 month old) or aged (20–22 month old) male BALB/c mice were treated with minocycline and LPS as described and euthanized 4 h later.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus cricetus (aka cricetus cricetus)
C: mouse (aka mus <genus>)
D: peromyscus
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'In a final study, adult (3–4 month old) or aged (20–22 month old) male BALB/c mice were treated with minocycline and LPS as described and euthanized 4 h later.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: peromyscus
C: eastern european house mouse (aka mus musculus musculus)
D: mus cricetus (aka cricetus cricetus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | F |
<Instruct>: Given the context 'LPS-induced TLR2 surface expression on microglia is reduced by minocycline
Because minocycline attenuated LPS-induced cytokine secretion and TLR2 mRNA expression in BV-2 cells we next sought to determine if minocycline suppresses markers of microglial activation in the brain of mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: western european house mouse (aka mus musculus domesticus)
F: None of the above. | C |
<Instruct>: Given the context 'Mice were injected i.p.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus sp. (mice (aka mus sp.))
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus cricetus (aka cricetus cricetus)
E: mouse (aka mus <genus>)
F: None of the above. | A |
<Instruct>: Given the context 'In this experiment, adult mice were treated with minocycline and LPS as described.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: peromyscus
D: eastern european house mouse (aka mus musculus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | A |
<Instruct>: Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: eastern european house mouse (aka mus musculus musculus)
B: peromyscus
C: mouse (aka mus musculus)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mouse (aka mus <genus>)
F: None of the above. | C |
<Instruct>: Given the context 'For example, at 8 h post LPS, social exploration was reduced by 35% in minocycline pretreated mice given LPS compared to a 67% reduction in vehicle pretreated mice given LPS (P < 0.001).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: peromyscus
B: house mouse (aka mus musculus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus castaneus (aka mus musculus castaneus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | B |
<Instruct>: Given the context 'While minocycline administration alone reduced food intake and body weight in control mice (P < 0.05, for each), it also protected against LPS-associated anorexia (Mino × LPS interaction, F(1, 60)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: western european house mouse (aka mus musculus domesticus)
C: peromyscus
D: mus <genus> (mice (aka mus <genus>))
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | A |
<Instruct>: Given the context 'In this experiment, mice were subjected to the same minocycline injection regimen and LPS challenge as above and sucrose preference was assessed 24–39 h post LPS injection.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: eastern european house mouse (aka mus musculus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'By 24 h post LPS injection, food and water intake returned to baseline and LPS treated mice still exhibited a marked reduction in sucrose preference from 24–39 h (F(1,59) = 14.3, P < 0.003).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: house mouse (aka mus musculus)
C: mice (aka mus <genus>) (aka mus <genus>)
D: mus <subgenus> (mus (aka mus <subgenus>))
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | B |
<Instruct>: Given the context 'For example, minocycline pretreated mice injected with LPS maintained the same strong preference for sucrose as saline and minocycline controls (i.e., approximately 85% preference).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: house mouse (aka mus musculus)
C: peromyscus
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | B |
<Instruct>: Given the context 'In this experiment, mice were subjected to the minocycline injection regimen and LPS challenge as above and cytokine mRNA levels were determined in the cortex and hippocampus 4 h after LPS injection.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus musculus (house mouse) (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: mus sp. (mice (aka mus sp.))
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'In this experiment, mice were subjected to the minocycline injection regimen and LPS challenge as above and cytokine mRNA levels were determined in the cortex and hippocampus 4 h after LPS injection.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mus castaneus (aka mus musculus castaneus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | F |
<Instruct>: Given the context 'In mice pretreated with vehicle, LPS markedly increased IL-1β mRNA levels in the hippocampus (F(1,31)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus musculus (house mouse) (aka mus musculus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: western european house mouse (aka mus musculus domesticus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | B |
<Instruct>: Given the context 'The LPS-induced IL-1β mRNA expression was reduced in both brain regions in mice receiving minocycline prior to LPS injection: (hippocampus, F(1,31)', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus sp. (mice (aka mus sp.))
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'It is important to note that IDO mRNA was undetected in saline treated mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: peromyscus
C: western european house mouse (aka mus musculus domesticus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | A |
<Instruct>: Given the context 'Therefore, the fold IDO change was relative to the IDO mRNA levels in mice receiving minocycline prior to LPS.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: mouse (aka mus <genus>)
C: mus cricetus (aka cricetus cricetus)
D: mus castaneus (aka mus musculus castaneus)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Minocycline attenuates LPS-induced exaggerated neuroinflammation in aged mice
Aged BALB/c mice (22–24 m) have an exaggerated neuroinflammatory response to LPS injection [10,13,14].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus <subgenus> (mus (aka mus <subgenus>))
B: mouse (aka mus musculus)
C: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus (aka mus <genus>) (aka mus <genus>)
F: None of the above. | B |
<Instruct>: Given the context 'Minocycline attenuates LPS-induced exaggerated neuroinflammation in aged mice
Aged BALB/c mice (22–24 m) have an exaggerated neuroinflammatory response to LPS injection [10,13,14].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
B: mus musculus (house mouse) (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: mus castaneus (aka mus musculus castaneus)
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'Therefore, we next sought to determine if the heightened inflammatory response in the brain of aged mice was reduced by minocycline.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: peromyscus
C: eastern european house mouse (aka mus musculus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | A |
<Instruct>: Given the context 'In this experiment, adult and aged mice were subjected to the minocycline injection regimen and LPS challenge as above.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mouse (aka mus <genus>)
D: mus cricetus (aka cricetus cricetus)
E: mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Moreover, LPS caused a greater increase in TLR2 mRNA in the hippocampus of aged mice compared to adults (LPS × Age interaction, F(1,63) = 12.70, P < 0.01).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus (house mouse) (aka mus musculus)
B: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
C: mus cricetus (aka cricetus cricetus)
D: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
E: peromyscus
F: None of the above. | A |
<Instruct>: Given the context 'Furthermore, minocycline pretreatment attenuated LPS-induced TLR2 mRNA levels in both adult and aged mice (Mino × LPS interaction, F(1,63) = 9.02, P < 0.004).
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <subgenus>) (aka mus <subgenus>)
B: house mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: eastern european house mouse (aka mus musculus musculus)
E: peromyscus
F: None of the above. | B |
<Instruct>: Given the context 'Furthermore, minocycline pretreatment attenuated LPS-induced TLR2 mRNA levels in both adult and aged mice (Mino × LPS interaction, F(1,63) = 9.02, P < 0.004).
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus domesticus (western european house mouse) (aka mus musculus domesticus)
B: mus castaneus (aka mus musculus castaneus)
C: mus <subgenus> (mus (aka mus <subgenus>))
D: mus (aka mus <genus>) (aka mus <genus>)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | F |
<Instruct>: Given the context 'Parallel to the results for TLR2, LPS caused a greater increase in IL-1β and IDO mRNA levels in hippocampus of aged mice compared to adults (Age × LPS, F(1,60) = 8.64, P < 0.01 for IL-1β and F(1,60) = 4.0, P < 0.05 for IDO).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus sp. (mice (aka mus sp.))
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | C |
<Instruct>: Given the context 'While LPS induced higher IL-6 mRNA levels in the hippocampus of both adult and aged mice (F(1,59) = 44.5, P < 0.001), there was not an Age × LPS interaction.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: house mouse (aka mus musculus)
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus cricetus (aka cricetus cricetus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | A |
<Instruct>: Given the context 'Taken together these data indicate that minocycline pretreatment was effective in attenuating the exaggerated neuroinflammation in aged mice.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mus cricetus (aka cricetus cricetus)
C: mus <genus> (mice (aka mus <genus>))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: house mouse (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'We have reported that stimulation of the peripheral immune system in older (20–24 m) BALB/c mice causes exaggerated neuroinflammation that is paralleled by prolonged sickness', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus castaneus (aka mus musculus castaneus)
B: eastern european house mouse (aka mus musculus musculus)
C: mus (aka mus <subgenus>) (aka mus <subgenus>)
D: mus musculus (house mouse) (aka mus musculus)
E: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
F: None of the above. | D |
<Instruct>: Given the context 'Here we show that minocycline treatment reduced LPS-induced TLR2 expression in BV-2 cells and on microglia isolated from adult mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus <genus> (mice (aka mus <genus>))
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mus domesticus (aka mus musculus domesticus)
D: house mouse (aka mus musculus)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | D |
<Instruct>: Given the context 'Moreover, we demonstrate that minocycline was effective in facilitating the recovery from LPS-induced sickness and preventing anhedonia in adult mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus <genus>) (aka mus <genus>)
B: mus (aka mus <subgenus>) (aka mus <subgenus>)
C: mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: peromyscus
F: None of the above. | C |
<Instruct>: Given the context 'Furthermore, we show that minocycline attenuated LPS-induced neuroinflammation in adults and normalized the exaggerated neuroinflammation in aged mice.
', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: western european house mouse (aka mus musculus domesticus)
B: mouse (aka mus musculus)
C: mus cricetus (aka cricetus cricetus)
D: eastern european house mouse (aka mus musculus musculus)
E: mus sp. (mice (aka mus sp.))
F: None of the above. | B |
<Instruct>: Given the context 'We have reported that IDO induction and activity is amplified in the brain of aged mice and is associated with prolonged depressive-like behavior [15].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mice (aka mus sp.) (aka mus sp.)
B: peromyscus
C: mouse (aka mus musculus)
D: western european house mouse (aka mus musculus domesticus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | C |
<Instruct>: Given the context 'Here we show that IDO mRNA induction is blocked by minocycline in the brain of both adult and aged mice (Figs. 5&7).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus castaneus (aka mus musculus castaneus)
C: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
D: mus musculus (house mouse) (aka mus musculus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | D |
<Instruct>: Given the context 'These data are consistent with a recent report showing a causal relationship between IDO activity and acute depressive effects in adult CD-1 mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus castaneus (aka mus musculus castaneus)
B: mice (aka mus sp.) (aka mus sp.)
C: mus musculus (house mouse) (aka mus musculus)
D: mus (aka mus <subgenus>) (aka mus <subgenus>)
E: mouse (aka mus <genus>)
F: None of the above. | C |
<Instruct>: Given the context 'These data are consistent with a recent report showing a causal relationship between IDO activity and acute depressive effects in adult CD-1 mice.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
B: mus <genus> (mice (aka mus <genus>))
C: mus castaneus (aka mus musculus castaneus)
D: mice (aka mus sp.) (aka mus sp.)
E: mus cricetus (aka cricetus cricetus)
F: None of the above. | F |
<Instruct>: Given the context 'Another interesting finding was that while minocycline pretreatment in adult mice attenuated LPS-induced brain IL-1β at 4 h (Fig. 5), it had no effect on plasma IL-1β levels (Fig. 6).', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus cricetus (aka cricetus cricetus)
B: peromyscus
C: mice (aka mus sp.) (aka mus sp.)
D: western european house mouse (aka mus musculus domesticus)
E: mus musculus (house mouse) (aka mus musculus)
F: None of the above. | E |
<Instruct>: Given the context 'Consistent with other aging and neuroinflammation studies, our data show that LPS caused exaggerated neuroinflammation in aged mice compared to adults', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus sp. (mice (aka mus sp.))
B: mus <subgenus> (mus (aka mus <subgenus>))
C: mus cricetus (aka cricetus cricetus)
D: mouse (aka mus musculus)
E: mus <genus> (mice (aka mus <genus>))
F: None of the above. | D |
<Instruct>: Given the context 'It is important to mention that while there was an age-related difference in MHC II expression in the hippocampus of saline treated mice (Fig.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mus cricetus (aka cricetus cricetus)
C: mus musculus (house mouse) (aka mus musculus)
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus castaneus (aka mus musculus castaneus)
F: None of the above. | C |
<Instruct>: Given the context 'These data differ from a previous report using BALB/c mice showing an increase in IL-6 in older mice [70].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus castaneus (aka mus musculus castaneus)
B: mus musculus (house mouse) (aka mus musculus)
C: mus cricetus (aka cricetus cricetus)
D: eastern european house mouse (aka mus musculus musculus)
E: mice (aka mus sp.) (aka mus sp.)
F: None of the above. | B |
<Instruct>: Given the context 'These data differ from a previous report using BALB/c mice showing an increase in IL-6 in older mice [70].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
C: mouse (aka mus musculus)
D: mus castaneus (aka mus musculus castaneus)
E: eastern european house mouse (aka mus musculus musculus)
F: None of the above. | C |
<Instruct>: Given the context 'This may be because the mice used in the present study were approximately 4 months younger than the mice used previously.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus domesticus (aka mus musculus domesticus)
B: mus castaneus (aka mus musculus castaneus)
C: peromyscus
D: house mouse (aka mus musculus)
E: mus <subgenus> (mus (aka mus <subgenus>))
F: None of the above. | D |
<Instruct>: Given the context 'This may be because the mice used in the present study were approximately 4 months younger than the mice used previously.', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: mus (aka mus <genus>) (aka mus <genus>)
B: house mouse (aka mus musculus)
C: mus castaneus (aka mus musculus castaneus)
D: mus cricetus (aka cricetus cricetus)
E: mus (aka mus <subgenus>) (aka mus <subgenus>)
F: None of the above. | B |
<Instruct>: Given the context '[13] and depressive-like behavior exhibited by aged BALB/c mice [15].', select the correct biomedical concept corresponding to 'mice'. Answer using one of the provided options. | <Options>: A: peromyscus
B: mouse (aka mus musculus)
C: mus (aka mus <genus>) (aka mus <genus>)
D: mus castaneus (aka mus musculus castaneus)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | B |
<Instruct>: Given the context 'List of abbreviations
3-Hydroxy-L-Kynuriene (3HK), Allophycocyanin (APC), Analysis of variance (ANOVA), Central Nervous System (CNS), Dulbecco's Modified Eagle's Medium (DMEM), Dimethyl Sulfoxide (DMSO), Experimental Autoimmune Encephalomyelitis (EAE), Enzyme Linked Immmunosorbent Assay (ELISA), Fluorescein Isothiocyanate (FITC), Fetal Bovine Serum (FBS), Hank's Balanced Salt Solution (HBSS), Indoleamine 2, 3 dioxygenase (IDO), Intraperitoneal (i.p.), Intracerebroventricular (i.c.v.), Interleukin (IL), Kynurenine (KYN), Lipopolysaccharide (LPS), Major Histocompatibility Complex class II (MHC II), Mitogen Activated Protein Kinase (MAP-kinase), Nuclear factor kappa B (NFκB), N-methyl-D-aspartate (NMDA), R-Phycoerthrin (PE), Quinolinic acid (QUIN), Statistical Analysis Systems (SAS), Standard Error of the Mean (SEM), Toll-like Receptor-2 (TLR2), and Tryptophan (TRP).
', select the correct biomedical concept corresponding to 'bovine'. Answer using one of the provided options. | <Options>: A: bos sp.
B: bos (cattle) (aka bos)
C: bovinae
D: bos indicus (bos primigenius indicus) (aka bos indicus)
E: dairy cow (aka bos taurus)
F: None of the above. | E |
<Instruct>: Given the context 'The authors affirm that there are no financial, personal or other relationships with other people or organizations that have inappropriately influenced or biased their research.
', select the correct biomedical concept corresponding to 'people'. Answer using one of the provided options. | <Options>: A: other (aka unidentified)
B: birds (aka aves)
C: musculus
D: human (aka homo sapiens)
E: kingdom
F: None of the above. | D |
<Instruct>: Given the context 'The authors affirm that there are no financial, personal or other relationships with other people or organizations that have inappropriately influenced or biased their research.
', select the correct biomedical concept corresponding to 'people'. Answer using one of the provided options. | <Options>: A: other (aka unidentified)
B: species group
C: suborder
D: animals (aka metazoa)
E: biota (aka cellular organisms)
F: None of the above. | F |
<Instruct>: Given the context 'Results
Among 28 human tetraspanin proteins, the TM1-3 sequences display a distinct heptad repeat motif (abcdefg)n.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: this
B: genus
C: birds (aka aves)
D: homo sapiens (human) (aka homo sapiens)
E: probles
F: None of the above. | D |
<Instruct>: Given the context 'Mutations of conserved glycines in human CD9 (Gly25 and Gly32 in TM1; Gly67 and Gly74 in TM2) caused aggregation of mutant proteins inside the cell.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo (humans) (aka homo)
B: homo sapiens (human) (aka homo sapiens)
C: placental mammals (aka eutheria)
D: this
E: genus
F: None of the above. | B |
<Instruct>: Given the context 'There are 32 putative tetraspanin family members in mammals, 37 in Drosophila melanogaster and 20 in Caenorhabditis elegans.', select the correct biomedical concept corresponding to 'drosophila melanogaster'. Answer using one of the provided options. | <Options>: A: melanogaster subgroup
B: hawaiian drosophila
C: drosophila melanogaster (sophophora melanogaster) (aka drosophila melanogaster)
D: drosophila <basidiomycete fungi> (drosophila) (aka drosophila <basidiomycete fungi>)
E: flies (aka diptera)
F: None of the above. | C |
<Instruct>: Given the context 'There are 32 putative tetraspanin family members in mammals, 37 in Drosophila melanogaster and 20 in Caenorhabditis elegans.', select the correct biomedical concept corresponding to 'caenorhabditis elegans'. Answer using one of the provided options. | <Options>: A: cyclostrongylus elegans
B: myzomyia elegans (aka anopheles elegans)
C: caenorhabditis drosophilae (rhabditis drosophilae) (aka caenorhabditis drosophilae)
D: enyo elegans (aka zodarion elegans)
E: rhabditis elegans (aka caenorhabditis elegans)
F: None of the above. | E |
<Instruct>: Given the context 'Mammalian tetraspanins such as CD9, CD63, CD81, CD82, CD151, rds/peripherin, and uroplakins Ia and Ib have been most extensively studied, with mouse knock-out models available for CD9', select the correct biomedical concept corresponding to 'mouse'. Answer using one of the provided options. | <Options>: A: mouse (aka mus <genus>)
B: mouse (aka mus musculus)
C: mus sp. (mice (aka mus sp.))
D: mus musculoides (mus musculoides enclavae) (aka mus musculoides)
E: mus musculus musculus (eastern european house mouse) (aka mus musculus musculus)
F: None of the above. | B |
<Instruct>: Given the context 'In this study, we carried out detailed sequence analysis of human tetraspanin TM domains.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: birds (aka aves)
B: homo sapiens (human) (aka homo sapiens)
C: probles
D: animals (aka metazoa)
E: placental mammals (aka eutheria)
F: None of the above. | B |
<Instruct>: Given the context 'Moreover, by using cysteine cross-linking we map a dimerization interface in the human CD9 protein, and show that conserved heptad motif glycine residues are also important for intermolecular CD9 associations.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: human (aka homo sapiens)
B: animals (aka metazoa)
C: kingdom
D: species
E: this
F: None of the above. | A |
<Instruct>: Given the context 'Results
Sequence analysis of tetraspanin transmembrane domains: presence of the heptad repeat motif
We focused our attention on 28 human tetraspanins identified from the SWISS-PROT and GenBank databases.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: homo sapiens (human) (aka homo sapiens)
B: genus
C: probles
D: primate (aka primates)
E: placental mammals (aka eutheria)
F: None of the above. | A |
<Instruct>: Given the context 'Figures 1 and 2 show a multiple sequence alignment of four TM domains of 28 human tetraspanins.', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: placental mammals (aka eutheria)
B: homo (humans) (aka homo)
C: probles
D: homo sapiens (human) (aka homo sapiens)
E: biota (aka cellular organisms)
F: None of the above. | D |
<Instruct>: Given the context 'No proline residues are found in TM domains 1–3 of human tetraspanins.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: genus
B: primate (aka primates)
C: human (aka homo sapiens)
D: mammals (aka mammalia)
E: homo (humans) (aka homo)
F: None of the above. | C |
<Instruct>: Given the context 'No proline residues are found in TM domains 1–3 of human tetraspanins.
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: genus
B: kingdom
C: species
D: humans (aka homo)
E: cellular organisms (biota) (aka cellular organisms)
F: None of the above. | F |
<Instruct>: Given the context 'For instance, in the leucine zipper of the yeast transcription factor GCN4, positions a and d contain Val and Leu residues, respectively, with an Asn residue in a single a position forming a hydrogen bond across the GCN4 dimer interface', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: saccharomyces hansenii (aka debaryomyces hansenii)
B: saccharomyces cf. cerevisiae
C: saccharomyces cerevisiae (saccharomyces cerevisiae (desm.) meyen ex e.c. hansen, 1883) (aka saccharomyces cerevisiae)
D: saccharomyces lactis (aka kluyveromyces lactis)
E: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
F: None of the above. | C |
<Instruct>: Given the context 'In human rhabdomyosarcoma RD cells, the wild-type fusion protein localized mostly in a reticular, intracellular pattern, without forming any large aggregates (Figure 5, panel A).', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: kingdom
B: probles
C: mammals (aka mammalia)
D: homo sapiens (human) (aka homo sapiens)
E: macrobiotus sapiens
F: None of the above. | D |
<Instruct>: Given the context 'Also, nearly identical results were obtained with human HT1080 cells (data not shown).
', select the correct biomedical concept corresponding to 'human'. Answer using one of the provided options. | <Options>: A: mammals (aka mammalia)
B: human (aka homo sapiens)
C: suborder
D: probles
E: primate (aka primates)
F: None of the above. | B |
<Instruct>: Given the context 'Other membrane proteins that use the GxxxG motif for homo- or heterodimerization include bacteriophage M13 coat proteins', select the correct biomedical concept corresponding to 'bacteriophage m13'. Answer using one of the provided options. | <Options>: A: bacteriophage m11 (aka enterobacteria phage m11)
B: staphylococcus phage m13
C: phage m13 (aka inovirus m13)
D: enterobacteria phage m1 (bacteriophage m1) (aka enterobacteria phage m1)
E: phage m13mp18 (bacteriophage m13mp18) (aka phage m13mp18)
F: None of the above. | C |
<Instruct>: Given the context '[45], yeast alpha factor receptor', select the correct biomedical concept corresponding to 'yeast'. Answer using one of the provided options. | <Options>: A: mycoderma cerevisiae (aka saccharomyces cerevisiae)
B: saccharomyceta
C: saccharomycotina (budding yeasts & others) (aka saccharomycotina)
D: saccharomyces hansenii (aka debaryomyces hansenii)
E: saccharomycetes (hemiascomycetes) (aka saccharomycetes)
F: None of the above. | A |
<Instruct>: Given the context '[59] used asparagine scanning mutagenesis to probe the interface of self-associating polyleucine helices by detecting their enhanced self-interaction in vitro and in the E. coli-based ToxR assay.', select the correct biomedical concept corresponding to 'e. coli'. Answer using one of the provided options. | <Options>: A: escherichia faecalis ('escherichia faecalis') (aka escherichia faecalis)
B: enterobacteriales (aka enterobacterales)
C: enterobacteria (aka enterobacteriaceae)
D: e. coli (aka escherichia coli)
E: escherichia coli b (escherichia coli (strain b)) (aka escherichia coli b)
F: None of the above. | D |
<Instruct>: Given the context '[62], M(3) muscarinic acetylcholine receptor [63], E. coli lactose permease', select the correct biomedical concept corresponding to 'e. coli'. Answer using one of the provided options. | <Options>: A: enterobacterales (enterobacteriaceae and related endosymbionts) (aka enterobacterales)
B: enterobacteria (aka enterobacteriaceae)
C: bacillus coli (aka escherichia coli)
D: escherichia
E: enterobacteriaceae bacterium
F: None of the above. | C |
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