question_id stringlengths 1 4 | question stringlengths 26 249 | pos_item_ids listlengths 1 5 | pos_item_contents listlengths 1 5 |
|---|---|---|---|
988 | Pseudoknots are not evolutionarily conserved in most eukaryotes. | [
"3033830"
] | [
"Identification and analysis of ribonuclease P and MRP RNA in a broad range of eukaryotes. RNases P and MRP are ribonucleoprotein complexes involved in tRNA and rRNA processing, respectively. The RNA subunits of these two enzymes are structurally related to each other and play an essential role in the enzymatic rea... |
989 | Pure neural progenitor cell (NPC) populations can only be obtained from cell cultures that undergo passaging, filtration, or other isolation and cell sorting methods. | [
"9988425"
] | [
"Niche-Independent Symmetrical Self-Renewal of a Mammalian Tissue Stem Cell. Pluripotent mouse embryonic stem (ES) cells multiply in simple monoculture by symmetrical divisions. In vivo, however, stem cells are generally thought to depend on specialised cellular microenvironments and to undergo predominantly asymme... |
990 | Pyridostatin decreases telomere fragility in BRCA2-deficient cells. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
992 | Pyridostatin deregulates G2/M progression. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
994 | Pyridostatin encourages proliferation of homologous recombination - defective cells. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
996 | Pyridostatin induces checkpoint activation. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
997 | Pyridostatin induces double-strand breaks accumulation. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
998 | Pyridostatin prevents double-strand breaks accumulation. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
999 | Pyridostatin reduces proliferation of homologous recombination - defective cells. | [
"16472469"
] | [
"Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds. G-quadruplex (G4)-forming genomic sequences, including telomeres, represent natural replication fork barriers. Stalled replication forks can be stabilized and restarted by homologous recombination (HR), which also repairs DNA double-st... |
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